HOMER3 (Human) Recombinant Protein (P01)

Catalog # : H00009454-P01 規格 : [ 10 ug ] [ 25 ug ] List All

Specification Application Image

Product Human HOMER3 full-length ORF ( NP_004829.2, 1 a.a. - 361 a.a.) Enzyme-linked Immunoabsorbent Assay Description: recombinant protein with GST-tag at N-terminal. Western Blot (Recombinant Sequence: MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRII protein) SIGGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLT QFAEKFQEVKEAARLAREKSQDGGELTSPALGLASHQVPPSPLVSANG Antibody Production PGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSN NKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTP Protein Array TGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREE TQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLD VRLFELSELREGLARLAEAAP

Host: Wheat Germ (in vitro)

Theoretical MW 66.3 (kDa):

Preparation in vitro wheat germ expression system Method:

Purification: Glutathione Sepharose 4 Fast Flow

Quality Control 12.5% SDS-PAGE Stained with Coomassie Blue. Testing:

Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Storage Store at -80°C. Aliquot to avoid repeated freezing and thawing. Instruction:

Note: Best use within three months from the date of receipt of this protein.

MSDS: Download

Datasheet: Download

Applications

Enzyme-linked Immunoabsorbent Assay

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Antibody Production

Protein Array

Gene Information

Entrez GeneID: 9454

GeneBank NM_004838.2 Accession#:

Protein NP_004829.2 Accession#:

Gene Name: HOMER3

Gene Alias: HOMER-3

Gene homer homolog 3 (Drosophila) Description:

Omim ID: 604800

Gene Ontology: Hyperlink

Gene Summary: This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants

Other Homer, neuronal immediate early gene, 3,Homer-3D protein Designations:

Related Disease Schizophrenia Schizophrenia

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