Human CCL17,TARC ELISA Kit

Product Datasheet

Catalog No: #EK5273

Orders: [email protected] Description Support: [email protected]

Product Name Human CCL17,TARC ELISA Kit

Specificity Human

Crossing Reactivity There is no detectable cross-reactivity with other relevant proteins.

Immunogen Type E.coli,A24-S94

Other Names C-C motif chemokine 17; CC chemokine TARC; Small-inducible cytokine A17; Thymus and

activation-regulated chemokine; CCL17; SCYA17, TARC;

Accession No. Q92583

Cell Localization Secreted.

Application Details

sensitivity:1pg mlDetect Range:31.2pg ml-2000pg mlsample_type:cell culture supernates cell lysates tissue homogenates serum and plasma (heparin

EDTA).capture_antibody:monoclonal antibody from mousedetection_antibody:polyclonal antibody from goatgene_name:CCL17protein_name:C-C motif

chemokine 17gene_full_name:C-C motif chemokine 17tissue_specificity: Expressed at high levels in thymus and at lowlevels in the lung colon and small

intestine.sequence_similarities:Belongs to the intercrine beta (chemokine CC) family. tmb_incubation:20-25minresearch_category:immunology|innate

Product Description

Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human CCL17,TARC

Background

protein_function: Chemotactic factor for T-lymphocytes but not monocytesor granulocytes. May play a role in T-cell development in thymusand in trafficking and activation of mature T-cells. Binds toCCR4..Chemokine(C-C motif) ligand 17(CCL17) is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine(TARC). CCL17 is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells.1 This chemokine specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4.1,2The gene for CCL17 is located on chromosome 16, in humans, along with other chemokines called CCL22 and CX3CL1.3,4 The standard used in this kit is recombinant human CCL17, consisting of 71 amino acids with the molecular weight of 8Kda.

Note: This product is for in vitro research use only and is not intended for use in humans or animals.

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