ATAGENIX LABORATORIES
Catalog Number:ATAP01668 Recombinant Human BMPR1A protein
Product Details
Summary
English name Recombinant Human BMPR1A protein
Purity >90% as determined by SDS-PAGE
Endotoxin level Please contact with the lab for this information.
Construction A DNA sequence encoding the human BMPR1A (Gln24-Arg152) was fused with
His tag
Accession # P36894
Host E.coli
Species Homo sapiens (Human)
Predicted Molecular Mass 15.57 kDa
Formulation Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are
shipped out with dry ice/blue ice unless customers require otherwise.
Stability &Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitution Reconstitute in sterile water for a stock solution.A copy of datasheet will be
provided with the products, please refer to it for details.
Background
Background Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser
/Thr protein kinase family and TGFB receptor subfamily, including the type I
receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a
single-pass type I membrane protein and highly expressed in skeletal muscle.
BMPR1A contains one GS domain and one protein protein kinase domain.
BMPR1A is necessary for the extracellular matrix depostition by osteoblasts.
BMPR1A can activate SMAD transcriptional regulators, binding with ligands.
Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease
Web:www.atagenix.com E-mail: [email protected] Tel: 027-87433958 ATAGENIX LABORATORIES
Catalog Number:ATAP01668 Recombinant Human BMPR1A protein
and hereditary mixed polyposis syndrome 2 (HMPS2).
Alternative Names Bone morphogenetic protein receptor type-1A,Short name:BMP type-1A receptor,
Short name:BMPR-1A,Activin receptor-like kinase 3,Short name:ALK-3,Serine
/threonine-protein kinase receptor R5,Short name:SKR5,CD_antigen: CD292.
Web:www.atagenix.com E-mail: [email protected] Tel: 027-87433958