ATP6V0E1 (NM 003945) Human Untagged Clone – SC111093 | Origene

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for SC111093

ATP6V0E1 (NM_003945) Human Untagged Clone Product data:

Product Type: Expression Plasmids Product Name: ATP6V0E1 (NM_003945) Human Untagged Clone Tag: Tag Free Symbol: ATP6V0E1 Synonyms: ATP6H; ATP6V0E; M9.2; Vma21; Vma21p Vector: pCMV6-XL5 E. coli Selection: Ampicillin (100 ug/mL) Cell Selection: None Fully Sequenced ORF: >OriGene ORF within SC111093 sequence for NM_003945 edited (data generated by NextGen Sequencing) ATGGCGTATCACGGCCTCACTGTGCCTCTCATTGTGATGAGCGTGTTCTGGGGCTTCGTC GGCTTCTTGGTGCCTTGGTTCATCCCTAAGGGTCCTAACCGGGGAGTTATCATTACCATG TTGGTGACCTGTTCAGTTTGCTGCTATCTCTTTTGGCTGATTGCAATTCTGGCCCAACTC AACCCTCTCTTTGGACCGCAATTGAAAAATGAAACCATCTGGTATCTGAAGTATCATTGG CCTTGA

Clone variation with respect to NM_003945.3 5' Read Nucleotide >OriGene 5' read for NM_003945 unedited Sequence: GCACGAGGGCCGACCATGGTCGTATCACGGCCTCACTGTGCCTCTCATTGTGATGAGCGT GTTCTGGGGCTTCGTCGGCTTCTTGGTGCCTTGGTTCATCCCTAAGGGTCCTAACCGGGG AGTTATCATTACCATGTTGGTGACCTGTTCAGTTTGCTGCTATCTCTTTTGGCTGATTGC AATTCTGGCCCAACTCAACCCTCTCTTTGGACCGCAATTGAAAAATGAAACCATCTGGTA TCTGAAGTATCATTGGCCTTGAGGAAGAAGACATGCTCTACAGTGCTCAGTCTTTGAGGT CACGAGAAGAGAATGCCTTCTAGATGCAAAATCACCTCCAAACCAGACCACTTTTCTTGA CTTGCCTGTTTTGGCCATTAGCTGCCTTAAACGTTAACAGCACATTTGAATGCCTTATTC TACAATGCAGCGTGTTTTCCTTTGCCTTTTTTGCACTTTGGTGAATTACGTGCCTCCATA ACCTGAACTGTGCCGACTCCACAAAACGATTATGTACTCTTCTGAGATAGAAGATGCTGT TCTTCTGAGAGATACGTTACTCTCTCCTTGGAATCTGTGGATTTGAAGATGGCTCCTGCC TTCTCACGTGGGAATCAGTGAAGTGTTTAGAAACTGCTGCAAGACAAACAAGACTCCAGT GNGGTGGTCAGTAGGAGAGCACGTTCAGAGGGAA

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 3 ATP6V0E1 (NM_003945) Human Untagged Clone – SC111093

3' Read Nucleotide >OriGene 3' read for NM_003945 unedited Sequence: TTGAACGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTCCATAAAAAGGAGGAAAATATTTATTCCAAAAGAATGGCAAAAAAAAAAAAT TCATCCTGAAAGTATAGTTGGGGGCGATTCTGTTGAAATGGCTTTTCCTTTTGAACGTGC TTTCCTACTGACCACCCCACTGGAGTCTTGTTTGTCTTGCAGCAGTTTCTAAACACTTCA CTGATTCCCACGTGAAAAGGCAGGAGCCATTTTCAAATCCACAGATTCCAAGGAAAGAGT AACGTATTTTTCAAAAAAACAGCATTTTTTATTTCAAAAAAGTACATAATCGTTTTGGGG AGTCGGCACAGTTCAGGTTATGGAGGCACGTAATTCACCAAAGTGCAAAAAAGGCAAAGG AAAACACCCTGCATTGTAAAATAAGGCATTCAAATGTGCTGTTAACGTTTAAGGCAGCTA ATGGCCAAAACAGGCAAGTCAAAAAAAGTGGTCTGGTTTGGAGGTGATTTTGCATCTAAA AGGCATTCTCTTCTCGTGACCTCAAAAACTGACCACTGTAAAGCATGTCTTCTTCCTCAA GGCCAATGATACTTCAAATACCAAATGGTTTCATTTTTCAATTGCGGTCCAAAGAGAGGG TTGAGTTGGGCCAAAATTGCAATCAGCCAAAAGAGATAGCAGCAAACTGAACAGGTCACC AACATGGTAATGATAACTCCCCGGTTAGGACCCTTAGGGATGAACCAGGCACCAAGAAGC CGACGAAGCCCCAGACACGCTCATCACAATGAGAGGCCAGTGAGGCCGTGATCGCATGGT CGCCTCGTGCCGATTCCGGCCGCCTATAGTGAGTCGTATACAAAATCTGACGTTCACTAA CGAGCTTGCTTAT

Restriction Sites: NotI-NotI ACCN: NM_003945 Insert Size: 880 bp OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). RefSeq: NM_003945.3, NP_003936.1 RefSeq Size: 894 bp RefSeq ORF: 246 bp Locus ID: 8992 UniProt ID: O15342 Protein Families: Transmembrane Protein Pathways: Epithelial cell signaling in Helicobacter pylori infection, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 3 ATP6V0E1 (NM_003945) Human Untagged Clone – SC111093

Gene Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V- ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is possibly part of the V0 subunit. Since two nontranscribed pseudogenes have been found in dog, it is possible that the localization to chromosome 2 for this gene by radiation hybrid mapping is representing a pseudogene. Genomic mapping puts the chromosomal location on 5q35.3. [provided by RefSeq, Jul 2008]