OSCAR (NM 206818) Human Tagged ORF Clone Product Data

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for RG216426

OSCAR (NM_206818) Human Tagged ORF Clone Product data:

Product Type: Expression Plasmids Product Name: OSCAR (NM_206818) Human Tagged ORF Clone Tag: TurboGFP Symbol: OSCAR Synonyms: PIgR-3; PIGR3 Vector: pCMV6-AC-GFP (PS100010) E. coli Selection: Ampicillin (100 ug/mL) Cell Selection: Neomycin ORF Nucleotide >RG216426 representing NM_206818 Sequence: Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC

ATGGCCCTGGTGCTGATCCTCCAGCTGCTGACCCTCTGGCCTCTGTGTCACACAGACATCACTCCGTCTG TGGCCATTATAGTCCCCCCAGCTTCATACCACCCTAAGCCATGGCTGGGAGCTCAGCCGGCTACAGTTGT GACCCCTGGGGTCAACGTGACCTTGAGATGCCGGGCACCCCAACCCGCTTGGAGATTTGGACTTTTCAAG CCTGGAGAGATCGCTCCCCTTCTCTTCCGGGATGTGTCCTCCGAGCTGGCAGAATTCTTTCTGGAGGAGG TGACTCCAGCCCAAGGGGGAATTTACCGCTGCTGCTACCGAAGGCCAGACTGGGGGCCGGGTGTCTGGTC CCAGCCCAGCGATGTCCTGGAGCTGCTGGTGACAGAGGAGCTGCCGCGGCCGTCGCTGGTGGCGCTGCCC GGGCCGGTGGTGGGTCCTGGCGCCAACGTGAGCCTGCGCTGCGCGGGCCGCCTGCGGAACATGAGCTTCG TGCTGTACCGCGAGGGCGTGGCGGCCCCGCTGCAGTACCGCCACTCCGCGCAGCCCTGGGCCGACTTCAC GCTGCTGGGCGCCCGCGCCCCCGGCACCTACAGCTGCTACTATCACACGCCCTCCGCGCCCTACGTGCTG TCGCAGCGCAGCGAGGTGCTGGTCATCAGCTGGGAAGGTGAGGGCCCTGAGGCCCGGCCCGCCTCCTCCG CCCCAGGAATGCAGGCCCCAGGACCTCCGCCCTCAGACCCAGGAGCCCAGGCCCCCAGCCTCTCCTCCTT CAGACCCAGGGGTCTAGTCCTGCAGCCCCTCCTCCCTCAGACCCAGGATTCCTGGGACCCAGCCCCTCCT CCCTCAGATCCAGGAGTC

ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 3 OSCAR (NM_206818) Human Tagged ORF Clone – RG216426

Protein Sequence: >RG216426 representing NM_206818 Red=Cloning site Green=Tags(s)

MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFK PGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALP GPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVL SQRSEVLVISWEGEGPEARPASSAPGMQAPGPPPSDPGAQAPSLSSFRPRGLVLQPLLPQTQDSWDPAPP PSDPGV

TRTRPLE - GFP Tag - V

Restriction Sites: SgfI-MluI Cloning Scheme:

Plasmid Map:

ACCN: NM_206818 ORF Size: 858 bp

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 3 OSCAR (NM_206818) Human Tagged ORF Clone – RG216426

OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

RefSeq: NM_206818.1, NP_996554.1 RefSeq Size: 1946 bp RefSeq ORF: 861 bp Locus ID: 126014 UniProt ID: Q8IYS5, A0A087WV17 Protein Families: Druggable Genome Gene Summary: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]