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Theorem 1.1. There exist no non-trivial block-transitive t-(n,k,λ)q designs for 2 6 t The proof of Theorem 1.1 relies on work of Bamberg and Penttila [3, Theorem 3.1], who determined all linear groups having orders with certain divisors. Their result in turn relies on Guralnick et al. [13], who make use the Aschbacher classification of maximal subgroups of clas- sical groups [1], and the classification of finite simple groups. We consider in Section 3 each of the cases determined by [3, Theorem 3.1] in order to obtain Theorem 1.1. The majority of cases involve a simple analysis, with the exception of those treated separately in Section 2 . In particular, the case treated in Lemma 2.5 involves an exhaustive computer search. In Section 1.1 we introduce notation and preliminary results for subspace designs. In Sec- tion 1.2 we discuss the concept of a primitive divisor and set up the application of [3]. Section 2 deals with several specific cases. Finally, in Section 3 we prove Theorem 1.1. 1.1 Subspace designs n In analogy with the binomial coefficient k we define the q-binomial coefficient, − n (qn − 1) ··· (qn k+1 − 1) = k . kq (q − 1) ··· (q − 1) The q-binomial coefficient is also sometimes referred to as the Gaussian coefficient. Similarly, N this time in analogy with the set k of all k-subsets of a set N, we denote the set of all k- dimensional subspaces of a vector space over F by V . V q k q Definition 1.2. Given integers n, k, t, and λ, with 1 6 t