THIS DOCUMENT IS IN DRAFT FORM, INCOMPLETE AND SUBJECT TO CHANGE AND THAT THE INFORMATION MUST BE READ IN CONJUNCTION WITH THE SECTION HEADED “WARNING” ON THE COVER OF THIS DOCUMENT. SUBSTANTIAL SHAREHOLDERS

SUBSTANTIAL SHAREHOLDERS

So far as our Directors are aware, immediately following completion of the [REDACTED] and assuming the [REDACTED] is not exercised, the following persons will have interests and/or short positions in the Shares or underlying shares of our Company which would fall to be disclosed pursuant to the provisions of Divisions 2 and 3 of Part XV of the SFO:

Approximate Approximate percentage of Approximate percentage of shareholding in percentage of shareholding in the total share shareholding in the total share capital of our the relevant capital of Number and Company as of class of Shares our Company Name of class of Shares the date of this after the after the Shareholder Nature of Interest held (1) Document [REDACTED](1) [REDACTED] (%) (%) (%)

Dr. Zheng(2) Beneficial owner 88,278,594 24.52 [REDACTED][REDACTED] Domestic Shares Interest in controlled 34,729,562 9.65 [REDACTED] corporations Domestic Shares

Hangzhou Yantai(2) Beneficial owner 19,031,297 5.29 [REDACTED][REDACTED] Domestic Shares

Hangzhou Hengtai(2) Beneficial owner 15,698,265 4.36 [REDACTED][REDACTED] Domestic Shares

QM32 Limited(3) Beneficial owner 34,071,947 9.46 [REDACTED][REDACTED] Unlisted Foreign Shares

Zhejiang Jiuren Interest in controlled 28,027,046 7.79 [REDACTED][REDACTED] Capital corporations Domestic Shares Management Co., Ltd. (浙江九仁資 本管理有限公 司)(4)

LAV Evergreen Beneficial owner 25,637,520 7.12 [REDACTED][REDACTED] () Co., Unlisted Foreign Limited(5) Shares

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Approximate Approximate percentage of Approximate percentage of shareholding in percentage of shareholding in the total share shareholding in the total share capital of our the relevant capital of Number and Company as of class of Shares our Company Name of class of Shares the date of this after the after the Shareholder Nature of Interest held (1) Document [REDACTED](1) [REDACTED] (%) (%) (%)

Jiangsu Jiequan Beneficial owner 23,517,076 6.53 [REDACTED][REDACTED] Lize Health Domestic Shares Industry Venture Capital Fund () (江蘇疌泉醴澤健 康產業創業投資基 金(有限合夥))(6)

Shanghai Liyao Interest in controlled 21,776,804 6.05 [REDACTED][REDACTED] Investment corporations Domestic Shares Management Co., Ltd. (上海禮曜投 資管理有限公 司)(7)

Suzhou Qiming Beneficial owner 16,055,165 4.46 [REDACTED][REDACTED] Ronghe Venture Domestic Shares Capital Partnership (Limited Partnership) (蘇州 啟明融合創業投 資合夥企業(有限 合夥)) (“ Qiming”)(8)

Power SUM Beneficial owner 6,958,131 1.93 [REDACTED][REDACTED] Limited(9) Unlisted Foreign Shares

QM153 Limited(10) Beneficial owner 6,858,828 1.91 [REDACTED][REDACTED] Unlisted Foreign Shares

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Notes: (1) As the Unlisted Foreign Shares held by QM32 Limited, LAV Evergreen (Hong Kong) Co., Limited, Power SUM Limited and QM153 Limited will not be converted into H Shares upon [REDACTED], the calculation is based on the total number of 286,473,574 Domestic Shares in issue, 73,526,426 Unlisted Foreign Shares in issue and [REDACTED] H Shares in issue immediately after completion of the [REDACTED], and assuming that the [REDACTED] is not exercised.

(2) Immediately after completion of the [REDACTED] and assuming the [REDACTED] is not exercised, Dr. Zheng beneficially owns 88,278,594 Domestic Shares of our Company. Dr. Zheng, being the sole general partner, controls Hangzhou Yantai and Hangzhou Hengtai, both of which are Employee Incentive Platforms. Therefore, under the SFO, in addition to his direct shareholding, Dr. Zheng is also deemed to be interested in the 19,031,297 Domestic Shares of our Company through Hangzhou Yantai and the 15,698,265 Domestic Shares of our Company through Hangzhou Hengtai, respectively.

(3) QM32 Limited is held as to 96.99% by Qiming Venture Partners V, L.P., which is managed by Qiming GP V, L.P., which is in turn managed by Qiming Corporate GP V, Ltd. Therefore, Qiming Venture Partners V, L.P., Qiming GP V, L.P. and Qiming Corporate GP V, Ltd. are deemed to be interested in the interest of QM32 Limited under the SFO.

(4) Zhejiang Jiuren Capital Management Co., Ltd. manages Hangzhou Jiuyao Equity Investment Partnership (Limited Partnership) (杭州九珧股權投資合夥企業(有限合夥)) (“Hangzhou Jiuyao”), Hangzhou Jiufu Equity Investment Partnership (Limited Partnership) (杭州九賦股權投資合夥企業(有限合夥)) (“Hangzhou Jiufu”), Hangzhou Yunbo Investment Partnership (Limited Partnership) (杭州雲帛投資合夥企業(有限合夥)) (“Hangzhou Yunbo”) and Hangzhou Jiuge Equity Investment Partnership (LimitedPartnership) (杭州九歌股 權投資合夥企業(有限合夥)) (“Hangzhou Jiuge”) in its capacity as the fund manager of these funds. Therefore, under SFO, Zhejiang Jiuren Capital Management Co., Ltd. is deemed to be interested in (i) the 10,683,565 Domestic Shares held by Hangzhou Jiuyao, (ii) the 10,683,565 Domestic Shares held by Hangzhou Jiufu, (iii) the 3,804,018 Domestic Shares held by Hangzhou Yunbo and (iv) the 2,855,898 Domestic Shares held by Hangzhou Jiuge.

(5) LAV Evergreen (Hong Kong) Co., Limited is wholly-owned by Lilly Asia Ventures Fund II, L.P., which is managed by Lilly Asia Ventures Fund GP, L.P., which in turn is managed by LAV Corporate GP, Ltd., a company wholly-owned by Mr. Shi Yi. Therefore, Lilly Asia Ventures Fund II, L.P., Lilly Asia Ventures Fund GP, L.P., LAV Corporate GP, Ltd. and Yi Shi are deemed to be interested in the 25,637,520 Unlisted Foreign Shares held by LAV Evergreen (Hong Kong) Co., Limited under the SFO.

(6) Jiangsu Jiequan Lize Health Industry Venture Capital Fund (Limited Partnership) is managed by Jiangsu Lize Investment Management Co., Ltd. (江蘇醴澤投資管理有限公司), a company wholly-owned by Mr. Zhu Yong. Therefore, Jiangsu Lize Investment Management Co., Ltd. and Mr. Zhu Yong are deemed to be interested in the 23,517,076 Domestic Shares held by Jiangsu Jiequan Lize Health Industry Venture Capital Fund (Limited Partnership) under the SFO.

(7) Li’an Venture Capital Center (Limited Partnership) and Suzhou Likang Equity Investment Center (Limited Partnership) are both managed by Shanghai Liyi Investment Management Partnership (Limited Partnership) (上海禮頤投資管理合夥企業(有限合夥)), which in turn is managed by Shanghai Liyao Investment Management Co., Ltd. Shanghai Liyao Investment Management Co., Ltd. is wholly-owned by Mr. Chen Fei (陳飛). Therefore, Mr. Chen Fei, Shanghai Liyi Investment Management Partnership (Limited Partnership) and Shanghai Liyao Investment Management Co., Ltd. are deemed to be interested in (i) the 11,983,877 Domestic Shares held by Shanghai Li’an Venture Capital Center (Limited Partnership) and (ii) the 9,792,927 Domestic Shares held by Suzhou Likang Equity Investment Center (Limited Partnership) under the SFO.

(8) Suzhou Qiming is managed by Suzhou Qicheng Investment Management Partnership (Limited Partnership) (蘇 州啟承投資管理合夥企業(有限合夥)), which is in turn managed by Shanghai Qichang Investment Consulting Co., Ltd. (上海啟昌投資諮詢有限公司), a company held as to 50% and 50% by Mr. Hu Xubo, a non-executive Director of our Company, and Ms. Yu Jia (于佳), respectively. Therefore, Suzhou Qicheng Investment Management Partnership (Limited Partnership), Shanghai Qichang Investment Consulting Co., Ltd., Mr. Hu Xubo and Ms. Yu Jia are deemed to be interested in the 16,055,165 Domestic Shares held by Suzhou Qiming under the SFO.

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(9) Power SUM Limited is wholly-owned by Master Summer Limited, which is controlled by CDBI Partners Fund I, L.P., a limited partnership with CDBI Partners GP, Ltd being its general partner and is turn controlled by Mr. Tan Ching (談慶). Therefore, Master Summer Limited, CDBI Partners Fund I, L.P., CDBI Partners GP, Ltd and Mr. Tan Ching are deemed to be interested in the 6,958,131 Unlisted Foreign Shares held by Power SUM Limited under the SFO.

(10) QM153 Limited is held as to 99.09% by Qiming Venture Partners VII, L.P., whose sole general partner is Qiming GP VII, LLC. Therefore, Qiming Venture Partners VII, L.P. and Qiming GP VII, LLC are deemed to be interested in the 6,858,828 Unlisted Foreign Shares held by QM153 Limited under the SFO.

For details of the substantial shareholders who will be, directly or indirectly, interested in 10% or more of the value of any class of Shares varying rights to vote in all circumstances at general meetings of any member of our Group, see “Appendix VI—Statutory and General Information—Further Information about our Directors, Supervisors, Senior Management and Substantial Shareholders—2. Substantial Shareholders.”

Save as disclosed herein, our Directors are not aware of any persons who will, immediately following completion of the [REDACTED] (assuming the [REDACTED]isnot exercised), have interests and/or short positions in Shares or underlying shares which would fall to be disclosed under the provisions of Divisions 2 and 3 of Part XV of the SFO.

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