SNRNP200 Antibody Cat. No.: 19-992

SNRNP200 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY:

Recombinant fusion protein containing a sequence corresponding to amino acids IMMUNOGEN: 1947-2136 of human SNRNP200 (NP_054733.2).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:500 - 1:2000

POSITIVE CONTROL: 1) Jurkat

2) A-431

3) HepG2

PREDICTED MOLECULAR Observed: 244kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

September 26, 2021 1 https://www.prosci-inc.com/snrnp200-antibody-19-992.html CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: SNRNP200

ASCC3L1, BRR2, HELIC2, RP33, U5-200KD, U5 small nuclear ribonucleoprotein 200 kDa helicase, BRR2 homolog, U5 snRNP-specific 200 kDa protein, activating signal cointegrator ALTERNATE NAMES: 1 complex subunit 3-like 1, bad response to refrigeration 2 homolog, small nuclear ribonucleoprotein 200kDa (U5), small nuclear ribonucleoprotein, U5 200kDa subunit

GENE ID: 23020

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins () U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This encodes one of the U5 snRNP-specific proteins. This protein belongs BACKGROUND: to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant . Alternatively spliced transcript variants encoding different isoforms have been found, but the full- length nature of these variants has not been determined.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 26, 2021 2 https://www.prosci-inc.com/snrnp200-antibody-19-992.html