SNRNP200 Antibody Cat. No.: 19-992
SNRNP200 Antibody
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human
Recombinant fusion protein containing a sequence corresponding to amino acids IMMUNOGEN: 1947-2136 of human SNRNP200 (NP_054733.2).
TESTED APPLICATIONS: WB
APPLICATIONS: WB: ,1:500 - 1:2000
POSITIVE CONTROL: 1) Jurkat
2) A-431
3) HepG2
PREDICTED MOLECULAR Observed: 244kDa WEIGHT:
Properties
PURIFICATION: Affinity purification
CLONALITY: Polyclonal
ISOTYPE: IgG
September 26, 2021 1 https://www.prosci-inc.com/snrnp200-antibody-19-992.html CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: SNRNP200
ASCC3L1, BRR2, HELIC2, RP33, U5-200KD, U5 small nuclear ribonucleoprotein 200 kDa helicase, BRR2 homolog, U5 snRNP-specific 200 kDa protein, activating signal cointegrator ALTERNATE NAMES: 1 complex subunit 3-like 1, bad response to refrigeration 2 homolog, small nuclear ribonucleoprotein 200kDa (U5), small nuclear ribonucleoprotein, U5 200kDa subunit
GENE ID: 23020
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs BACKGROUND: to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full- length nature of these variants has not been determined.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 26, 2021 2 https://www.prosci-inc.com/snrnp200-antibody-19-992.html