Table S2; Full Gene List Based on Need for Mechanical Ventilation Before 2.5 Log Cut-Off

Table S2; Full Gene List based on Need for Mechanical Ventilation before 2.5 log cut-off.

Gene Probe Set ID p-value Median fold change HLA-DQA1/DQA2 Major histocompatibility complex, class II, DQ alpha 1/2 212671_s_at 0,00000 -2,84819 TRIB2 Tribbles homolog 2 (Drosophila) 202478_at 0,00000 -2,18414 NR4A2 Nuclear receptor subfamily 4, group A, member 2 204622_x_at 0,00000 -2,02076 NR4A2 Nuclear receptor subfamily 4, group A, member 2 216248_s_at 0,00000 -1,95761 MUC13 Mucin 13 218687_s_at 0,00002 -3,40989 TNFSF10 Tumor necrosis factor superfamily, member 10 202688_at 0,00002 -2,49353 MXRA5 Matrix-remodelling associated 5 209596_at 0,00002 -2,02161 GZMA Granzyme A 205488_at 0,00003 -2,70209 CFB Complement factor B 202357_s_at 0,00003 -2,53650 LGALS3BP Lectin, galactoside-binding, soluble, 3 binding protein 200923_at 0,00003 -1,91567 UBD Ubiquitin D 205890_s_at 0,00004 -3,54059 MSP β-microseminoprotein 210297_s_at 0,00005 -2,91614 GBP1 Guanylate binding protein 1 202270_at 0,00007 -1,78777 AKR1C1 Aldo-keto reductase family 1, member C1 216594_x_at 0,00009 -2,49039 CLEC5A C-type lectin domain family 5, member A 219890_at 0,00010 2,36898 AKR1C2 Aldo-keto reductase family 1, member C2 209699_x_at 0,00011 -2,89072 AKR1C1 Aldo-keto reductase family 1, member C1 204151_x_at 0,00011 -2,61119 SPINK1 Serine peptidase inhibitor, Kazal type 1 206239_s_at 0,00011 2,32174 MSP β-microseminoprotein 207430_s_at 0,00013 -2,73207 GZMB Granzyme B 210164_at 0,00015 -2,70688 AQP3 Aquaporin 3 39248_at 0,00018 -2,95154 TFF1 Trefoil factor 1 205009_at 0,00019 -2,53729 GNLY Granulysin 37145_at 0,00022 -1,93698 Unannotated n/a 235229_at 0,00023 -2,20729 SYTL2 Synaptotagmin-like 2 232914_s_at 0,00026 -2,04847 UPK1B Uroplakin 1B 210065_s_at 0,00030 -2,31083 SAA1, SAA2 Serum amyloid A1, serum amyloid A2 214456_x_at 0,00035 -2,34207 ALDH1A1 Aldehyde dehydrogenase 1 family, member A1 212224_at 0,00043 -2,41902 NCOA7 Nuclear receptor coactivator 7 225344_at 0,00046 -2,08015 CCL7 Chemokine ligand 7 208075_s_at 0,00061 2,70079 HMGN3 High mobility group nucleosomal binding domain 3 209377_s_at 0,00068 -1,79715 TOX3 TOX high mobility group box family member 3 214774_x_at 0,00072 -2,19080 GALNT12 Polypeptide GalNAc transferase 12 218885_s_at 0,00072 -1,79081 WFDC2 WAP four-disulfide core domain 2 203892_at 0,00073 -1,94166

CLIC5 Chloride intracellular channel 5 213317_at 0,00075 -2,26771 WDR78 WD repeat domain 78 1554140_at 0,00082 -2,56061 SAA1, SAA2 Serum amyloid A1, serum amyloid A2 208607_s_at 0,00090 -2,33414 LOC100506582 n/a 238720_at 0,00104 -3,27600 ADH1C Alcohol dehydrogenase 1C (class I) 206262_at 0,00107 -2,43114 C21orf63 n/a 227188_at 0,00107 -1,63502 Unannotated n/a 237009_at 0,00121 -2,17973 TMC5 Transmembrane channel-like 5 219580_s_at 0,00147 -1,67413 TOX3 TOX high mobility group box family member 3 216623_x_at 0,00151 -2,17008 TSPAN8 Tetraspanin 8 203824_at 0,00157 -2,81420 NCRNA00263 Non-protein coding RNA 263 225457_s_at 0,00159 -2,16607 SLC6A14 Solute carrier family 6, member 14 219795_at 0,00164 -2,16607 PROM1 Prominin 1 204304_s_at 0,00178 -2,23263 C20orf114 n/a 226067_at 0,00184 -2,81622 PIGR Polymeric immunoglobulin receptor 226147_s_at 0,00192 -2,37475 EPCAM Epithelial cell adhesion molecule 201839_s_at 0,00209 -1,72765 CD69 CD69 molecule 209795_at 0,00211 -1,99673 SELENBP1 Selenium binding protein 1 214433_s_at 0,00216 -2,46250 IDO1 Indoleamine 2,3-dioxygenase 1 210029_at 0,00222 -2,27200 Unannotated n/a 239979_at 0,00236 -2,06713 EPSTI1 Epithelial stromal interaction 1 235276_at 0,00252 -1,99738 SLC26A4 Solute carrier family 26, member 4 206529_x_at 0,00264 -4,05345 NR2F2 Nuclear receptor subfamily 2, group F, member 2 209120_at 0,00271 -2,17448 EFHC1 EF-hand domain containing 1 219833_s_at 0,00278 -2,14801 LAMP3 Lysosomal-associated membrane protein 3 205569_at 0,00280 -2,25157 GBP1 Guanylate binding protein 1 202269_x_at 0,00317 -2,20274 CLIC6 Chloride intracellular channel 6 227742_at 0,00326 -1,96962 PTPRK Protein tyrosine phosphatase, receptor type, K 203038_at 0,00343 -1,90518 MECOM MDS1 and EVI1 complex locus 226420_at 0,00348 -1,54776 PRSS23 Protease, serine, 23 202458_at 0,00353 -2,38698 SPINK7 Serine peptidase inhibitor, Kazal type 7 223720_at 0,00397 1,84453 GBP1 Guanylate binding protein 1 231578_at 0,00416 -3,99393 PLUNC Palate, lung and nasal epithelium associated 220542_s_at 0,00463 -2,83308 C9orf135 n/a 243610_at 0,00469 -1,98283 ABCA13 ATP-binding cassette, sub-family A, member 13 1553605_a_at 0,00483 -1,92088 C9orf24 n/a 229012_at 0,00484 -2,75439 MUC5AC Mucin 5AC 214385_s_at 0,00497 -2,61658 CXCL10 Chemokine ligand 10 204533_at 0,00512 -2,66733 CXCL11 Chemokine ligand 11 211122_s_at 0,00513 -3,36876 IFI44 Interferon-induced protein 44 214059_at 0,00518 -1,84566 PRSS23 Protease, serine, 23 226279_at 0,00526 -2,98035 C11orf70 n/a 224463_s_at 0,00787 -2,86397 SOX2 SRY-box 2 228038_at 0,00808 -2,24204 SNTN Sentan, cilia apical structure protein 239150_at 0,00828 -2,76349 IFIT1 Interferon-induced protein with tetratricopeptide repeats 1 203153_at 0,00834 -1,62830 RDH10 Retinol dehydrogenase 10 226021_at 0,00863 -1,98464 CXCL11 Chemokine ligand 11 210163_at 0,00944 -2,70538 CRNDE Colorectal neoplasia differentially expressed 238021_s_at 0,00989 -2,30644 SERPINB3 Serpin peptidase inhibitor, clade B, member 3 209719_x_at 0,01044 -2,27181 HLA-DRB4 Major histocompatibility complex, class II, DR beta 4 209728_at 0,01098 -4,24281 CYP4B1 Cytochrome P450, family 4, subfamily B, polypeptide 1 210096_at 0,01099 -2,27502 RARRES1 Retinoic acid receptor responder 1 221872_at 0,01201 -3,18906 CP Ceruloplasmin 227253_at 0,01253 -2,43459 RARRES1 Retinoic acid receptor responder 1 206392_s_at 0,01308 -2,94252 IFI44L Interferon-induced protein 44-like 204439_at 0,01372 -1,56537 LEP Leptin 207092_at 0,01649 1,78763 LRP11 Low density lipoprotein receptor-related protein 11 225060_at 0,01968 -1,23345 CDC20B Cell division cycle 20 homolog B 240161_s_at 0,02499 -2,06883 Major histocompatibility complex, class II, DQ alpha 1 213831_at 0,03911 -2,03014 HLA-DQA1