UXT Antibody

CATALOG NUMBER: 30-715

Antibody used in WB on Human HepG2 at 2.5 ug/ml.

Specifications SPECIES REACTIVITY: Dog, Human TESTED APPLICATIONS: ELISA, WB APPLICATIONS: UXT antibody can be used for detection of UXT by ELISA at 1:312500. UXT antibody can be used for detection of UXT by western blot at 2.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. USER NOTE: Optimal dilutions for each application to be determined by the researcher. POSITIVE CONTROL: 1) Cat. No. 1211 - HepG2 Cell Lysate PREDICTED MOLECULAR 19 kDa, 18 kDa WEIGHT: IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UXT. HOST SPECIES: Rabbit

Properties PURIFICATION: Antibody is purified by protein A chromatography method. PHYSICAL STATE: Lyophilized BUFFER: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 uL of distilled water. Final antibody concentration is 1 mg/mL. CONCENTRATION: 1 mg/ml STORAGE CONDITIONS: For short periods of storage (days) store at 4˚C. For longer periods of storage, store UXT antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. CLONALITY: Polyclonal CONJUGATE: Unconjugated

Additional Info ALTERNATE NAMES: UXT, ART-27, STAP1 ACCESSION NO.: NP_705582 PROTEIN GI NO.: 24041018 OFFICIAL SYMBOL: UXT GENE ID: 8409

Background BACKGROUND: UXT is a novel protein which is highly conserved in mouse. It interacts with the N-terminus of the androgen receptor and plays a role in facilitating receptor-induced transcriptional activation. It is also likely to be involved in tumorigenesis as it is abundantly expressed in tumor tissues.This gene encodes a novel protein which is highly conserved in mouse. It interacts with the N-terminus of the androgen receptor and plays a role in facilitating receptor-induced transcriptional activation. It is also likely to be involved in tumorigenesis as it is abundantly expressed in tumor tissues. This gene is part of a gene cluster on chromosome Xp11.23. Alternative splicing results in 2 transcript variants encoding different isoforms. REFERENCES: 1) Zhao, H., (2005) Mol. Biol. Cell 16 (12), 5857-5865.

FOR RESEARCH USE ONLY

December 12, 2016