JOURNAL OF

Volume 66 April 1992 No. 4

MINIREVIEW Protective Immune Response against Foot-and-Mouth Kenneth C. McCullough, Franco 1835-1840 Disease De Simone, Emiliana Brocchi, Lorenzo Capucci, John R. Crowther, and Ulrich Kihm ANIMAL Repair and Mutagenesis of the of a Deletion Cheri A. Koetzner, Monica M. 1841-1848 Mutant of the Coronavirus Mouse Hepatitis by Parker, Cynthia S. Ricard, Targeted RNA Recombination Lawrence S. Sturman, and Paul S. Masters trans-Dominant Inhibition of Human Immunodeficiency Thomas J. Hope, Nicola P. Klein, 1849-1855 Virus Type 1 Rev Occurs through Formation of Inactive Melissa E. Elder, and Tristram G. Complexes Parslow Gag of the Highly Replicative MN Strain of Human Louis E. Henderson, Michelle A. 1856-1865 Immunodeficiency Virus Type 1: Posttranslational Bowers, Raymond C. Sowder II, Modifications, Proteolytic Processings, and Complete Amino Stefan A. Serabyn, Donald G. Acid Sequences Johnson, Julian W. Bess, Jr., Larry 0. Arthur, Duncan K. Bryant, and Catherine Fenselau Mutations in the Principal Neutralization Determinant of Raymond J. Grimaila, Barbara A. 1875-1883 Human Immunodeficiency Virus Type 1 Affect Syncytium Fuller, Paul D. Rennert, M. Bud Formation, Virus Infectivity, Growth Kinetics, and Nelson, Marie-Louise Neutralization Hammarskjold, Barbara Potts, Michael Murray, Scott D. Putney, and Gary Gray Subacute Sclerosing Panencephalitis Virus Dominantly Akiko Hirano 1891-1898 Interferes with Replication of Wild-Type Measles Virus in a Mixed Infection: Implication for Viral Persistence BHRF1 of Epstein-Barr Virus, Which Is Homologous to May-Ann Lee and John L. Yates 1899-1906 Human Proto- bcl2, Is Not Essential for Transformation of B Cells or for Virus Replication In Vitro The Hantaan Vius M-Segment Glycoproteins Gl and G2 Michael N. Pensiero and John Hay 1907-1914 Can Be Expressed Independently The Sequence Context of the Initiation Codon in the Monique V. Davies and Randal J. 1924-1932 Encephalomyocarditis Virus Leader Modulates Efficiency Kaufman of Internal Translation Initiation Spacing Is Crucial for Coordination of Domain Functions Ramon Parsons and Peter 1933-1942 within the Simian Virus 40 Core Origin of Replication Tegtmeyer CArG, CCAAT, and CCAAT-Like Protein Binding Sites in Karen R. Zachow and Kathleen F. 1959-1970 Avian Enhancers Conklin Gliotoxin: Inhibitor of Poliovirus RNA Synthesis That Pedro L. Rodriguez and Luis 1971-1976 Blocks the Viral RNA Polymerase 3DI°o Carrasco Inhibition of Poliovirus RNA Synthesis by Brefeldin A Laurie A. Maynell, Karla 1985-1994 Kirkegaard, and Michael W. Klymkowsky v-Src Enhances Phosphorylation at Ser-282 of the Rous Steven R. Mumm, Robert Horton, 1995-1999 Sarcoma Virus and Duane P. Grandgenett Inhibition of Human Immunodeficiency Virus Type 1 Tat Richard Carroll, B. Matija Peterlin, 2000-2007 Activity by Coexpression of Heterologous trans Activators and David Derse

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Functional Comparison of the Basic Domains of the Tat B. Elangovan, T. Subramanian, 2031-2036 Proteins of Human Immunodeficiency Virus Types 1 and 2 and G. Chinnadurai in trans Activation Molecular Variants of Human Papillomavirus Type 16 from Shih-Yen Chan, Lisa Ho, 2057-2066 Four Continents Suggest Ancient Pandemic Spread of the Chi-Keong Ong, Vincent Chow, Virus and Its Coevolution with Humankind Bernd Drescher, Matthias Durst, Jan ter Meulen, Luisa Villa, Jeff Luande, Hans N. Mgaya, and Hans-Ulrich Bernard Random Mutagenesis of the Thymidine Kinase of Tatsuo Suzutani, Simon F. Lacey, 2118-2124 Varicella-Zoster Virus Kenneth L. Powell, Dorothy J. M. Purifoy, and Robert W. Honess Three-Dimensional Structure of Single-Shelled Bluetongue B. V. Venkataram Prasad, S. 2135-2142 Virus Yamaguchi, and P. Roy Quantitation of a Lentivirus in Its Natural Host: Simian Susanne Hartung, Klaus Boller, 2143-2149 Immunodeficiency Virus in African Green Monkeys Klaus Cichutek, Stephen G. Norley, and Reinhard Kurth Reovirus Polypeptide or3 and N-Terminal Myristoylation of Lucia Tillotson and Aaron J. 2180-2186 Polypeptide ,ul Are Required for Site-Specific Cleavage to Shatkin ,u1C in Transfected Cells A Deletion in the Simian Virus 40 Large T Impairs Catharina Maulbecker, Ian Mohr, 2195-2207 Lytic Replication in Monkey Cells In Vivo but Enhances Yakov Gluzman, James DNA Replication In Vitro: New Complementation Function Bartholomew, and Michael of T Antigen Botchan Antigenic Structure of Human Hepatitis A Virus Defined by Li-Hua Ping and Stanley M. 2208-2216 Analysis of Escape Mutants Selected against Murine Lemon Monoclonal Detection of Replication-Competent and Pseudotyped Jaculyn Kimpton and Michael 2232-2239 Human Immunodeficiency Virus with a Sensitive Line Emerman on the Basis of Activation of an Integrated 13-Galactosidase Gene A Novel Glycoprotein, gL, Forms a L. Hutchinson, H. Browne, V. 2240-2250 Complex with Glycoprotein H (gH) and Affects Normal Wargent, N. Davis-Poynter, S. Folding and Surface Expression of gH Primorac, K. Goldsmith, A. C. Minson, and D. C. Johnson VPg Gene Amplification Correlates with Infective Particle Matthias M. Falk, Francisco 2251-2260 Formation in Foot-and-Mouth Disease Virus Sobrino, and Ewald Beck Identification of Dominant-Negative Mutants of the Herpes Peter C. Weber and Brian Wigdahl 2261-2267 Simplex Virus Type 1 Immediate-Early Protein ICPO Detection of Receptor-Specific Murine Virus Michael J. Kadan, Sabine Sturm, 2281-2287 Binding to Cells by Immunofluorescence Analysis W. French Anderson, and Martin A. Eglitis Low Degree of Human T-Cell Leukemia/ Virus Antoine Gessain, Robert C. Gallo, 2288-2295 Type I Genetic Drift In Vivo as a Means of Monitoring and Genoveffa Franchini V'iral Transmission and Movement of Ancient Human Populations Human Immunodeficiency Virus Type 1 Glycoprotein Bruce Crise and John K. Rose 2296-2301 Precursor Retains a CD4-p56kk Complex in the Endoplasmic Reticulum Assembly of Hepatitis Delta Virus Particles Wang-Shick Ryu, Manfred , 2310-2315 and John Taylor Replication of Nodamura Virus after of Viral L. Andrew Ball, Joseph M. 2326-2334 RNA into Mammalian Cells in Culture Amann, and Bonnie K. Garrett Cellular Expression of a Functional Nodavirus RNA L. Andrew Ball 2335-2345 Replicon from Vaccinia Virus Vectors

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The Bovine Papillomavirus Constitutive Enhancer Is Scott B. Vande Pol and Peter M. 2346-2358 Essential for Viral Transformation, DNA Replication, and Howley the Maintenance of Latency Both Substrate and Target Oligonucleotide Sequences Affect Andrew D. Leavitt, Robert B. 2359-2368 In Vitro Integration Mediated by Human Immunodeficiency Rose, and Harold E. Varmus Virus Type 1 Integrase Protein Produced in Saccharomyces cerevisiae Role of the Apical Stem in Maintaining the Structure and Kenneth H. Mellits, Tsafrira 2369-2377 Function of Adenovirus Virus-Associated RNA Pe'ery, and Michael B. Mathews Homologous Recombination of Copackaged Retrovirus Heidi Stuhlmann and Paul Berg 2378-2388 during Reverse Transcription Target Cell-Specific Determinants of Membrane Fusion Louise Bergeron, Nancy Sullivan, 2389-2397 within the Human Immunodeficiency Virus Type 1 gpl20 and Joseph Sodroski Third Variable Region and gp4l Amino Terminus Studies on the Fusion Peptide of a Paramyxovirus Fusion Curt M. Horvath and Robert A. 2443-2455 Glycoprotein: Roles of Conserved Residues in Lamb Interaction between Retroviral U5 RNA and the T*C Loop Ashok Aiyar, David Cobrinik, 2464-2472 of the tRNATrP Primer Is Required for Efficient Initiation of Zheng Ge, H.-J. Kung, and Reverse Transcription Jonathan Leis Inhibition of Human Immunodeficiency Virus Type 1 Rev Satoshi Kubota, Rika Furuta, 2510-2513 Function by a Rev Mutant Which Interferes with Masatoshi Maki, and Masakazu Nuclear/Nucleolar Localization of Rev Hatanaka Probing Protein-DNA Interactions at the Long Terminal Francesca Demarchi, Pierlanfranco 2514-2518 Repeat of Human Immunodeficiency Virus Type 1 by In D'Agaro, Arturo Falaschi, and Vivo Footprinting Mauro Giacca Evolutionary Insights on the Origin of Human T-Cell Michael P. Sherman, Nitin K. 2556-2563 Lymphoma/Leukemia Virus Type I (HTLV-I) Derived from Saksena, Dipak K. Dube, Richard Sequence Analysis of a New HTLV-I Variant from Papua Yanagihara, and Bernard J. Poiesz New Guinea Definition of the Human Immunodeficiency Virus Type 1 Irene Weichselbraun, G. King 2583-2587 Rev and Human T-Cell Leukemia Virus Type I Rex Protein Farrington, James R. Rusche, Activation Domain by Functional Exchange Ernst Bohnlein, and Joachim Hauber VIRUS-CELL INTERACTIONS Induced Expression of the Endogenous Beta Interferon Gene Ulrich Nielsch, Richard Pine, 1884-1890 in Adenovirus Type 5-Transformed Rat Fibroblasts Stephen G. Zimmer, and Lee E. Babiss Expression of Intracisternal A-Particle-Related Retroviral Frank U. Reuss 1915-1923 Element-Encoded Envelope Proteins Detected in Cell Lines The Vaccinia Virus K3L Gene Product Potentiates Monique V. Davies, Orna 1943-1950 Translation by Inhibiting Double-Stranded-RNA-Activated Elroy-Stein, Rosemary Jagus, Protein Kinase and Phosphorylation of the Alpha Subunit of Bernard Moss, and Randal J. Eukaryotic Initiation Factor 2 Kaufman Class I Major Histocompatibility Proteins Are an Essential Walter C. Breau, Walter J. 2037-2045 Component of the Simian Virus 40 Receptor Atwood, and Leonard C. Norkin An Orthopoxvirus Serpinlike Gene Controls the Ability of Peter C. Turner and Richard W. 2076-2085 Infected Cells To Fuse Moyer Novel Human Endogenous Sequences Related to Human M. S. Horwitz, M. T. 2170-2179 Immunodeficiency Virus Type 1 Boyce-Jacino, and A. J. Faras Differentiation-Dependent Human Immunodeficiency Virus Steven L. Zeichner, Gabor Hirka, 2268-2273 Long Terminal Repeat Regulatory Elements Active in Peter W. Andrews, and James C. Human Teratocarcinoma Cells Alwine

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An AP-1 Binding Site Is the Predominant cis-Acting Erik J. Wade, Kevin M. Klucher, 2407-2417 Regulatory Element in the 1.2-Kilobase Early RNA and Deborah H. Spector of Human Cytomegalovirus Heterogeneity of the Mutation Rates of Influenza A Viruses: Paula Suairez, Juan Valcaircel, and 2491-2494 Isolation of Mutator Mutants Juan Ortin Human Immunodeficiency Virus Type 1 Entry into T Cells: Shan Lu, Scott D. Putney, and 2547-2550 More-Rapid Escape from an Anti-V3 Loop Than from an Harriet L. Robinson Antireceptor Simian Virus 40 Small t Antigen trans Activates the Mary R. Loeken 2551-2555 Adenovirus E2A Promoter by Using Mechanisms Distinct from Those Used by Adenovirus ElA Human and Mouse Mx Proteins Inhibit Different Steps of Jovan Pavlovic, Otto Haller, and 2564-2569 the Influenza Virus Multiplication Cycle Peter Staeheli Macrophage Tropism Determinants of Human Peter Westervelt, David B. 2577-2582 Immunodeficiency Virus Type 1 In Vivo Trowbridge, Leon G. Epstein, Benjamin M. Blumberg, Yuexia Li, Beatrice H. Hahn, George M. Shaw, Richard W. Price, and Lee Ratner Human Immunodeficiency Virus Type 1 Tropism for Brain Norman E. Sharpless, William A. 2588-2593 Microglial Cells Is Determined by a Region of the O'Brien, Eric Verdin, Conrad V. Glycoprotein That Also Controls Macrophage Tropism Kufta, Irvin S. Y. Chen, and Monique Dubois-Dalcq

VIRAL AND CELLULAR Mutations in the SH3 Domain of the src Oncogene Which David S. Wages, Jeffrey Keefer, 1866-1874 Decrease Association of Phosphatidylinositol 3'-Kinase Thomas B. Rall, and Michael J. Activity with pp60v" and Alter Cellular Morphology Weber Immortalization of Primary Epithelial Cells Requires First- Margaret P. Quinlan and Janet L. 2020-2030 and Second-Exon Functions of Adenovirus Type 5 12S Douglas The E6 and E7 of Human Papillomavirus Type 6 Christine L. Halbert, G. William 2125-2134 Have Weak Immortalizing Activity in Human Epithelial Demers, and Denise A. Galloway Cells Overexpression of the E1B 55-Kilodalton (482R) Protein of Shiyun Zhang, Stanley Mak, and 2302-2309 Human Adenovirus Type 12 Appears To Permit Efficient Philip E. Branton Transformation of Primary Baby Rat Kidney Cells in the Absence of the E1B 19-Kilodalton Protein Structure-Function Analysis of the Human Papillomavirus William C. Phelps, Karl Munger, 2418-2427 Type 16 E7 Oncoprotein Carole L. Yee, Julie A. Barnes, and Peter M. Howley Transformation by Hamster Polyomavirus: Identification Laurence Goutebroze and Jean 2495-2504 and Functional Analysis of the Early Genes Feunteun Mouse Mammary Tumor Gene int-3: a Member of the notch Joan Robbins, Bruno J. Blondel, 2594-2599 Gene Family Transforms Mammary Epithelial Cells Daniel Gallahan, and Robert Callahan BACTERIAL VIRUSES Ar+ Plasma-Induced Damage to DNA in A. Elliot C. Mendelson, William W. 2226-2231 Implications for the Arrangement of DNA in the Phage Newcomb, and Jay C. Brown Head Reversion of Q,B RNA Phage Mutants by Homologous RNA Kampan Palasingam and Patrick 2435-2442 Recombination N. Shaklee

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VIRAL PATHOGENESIS AND IMMUNITY A Single Base Deletion in the 5' Noncoding Region of A. E. Pritchard, M. A. Calenoff, S. 1951-1958 Theiler's Virus Attenuates Neurovirulence Simpson, K. Jensen, and H. L. Lipton Gamma Interferon-Dependent Clearance of Cytomegalovirus Pero Lucin, Ivica Pavic, Bojan 1977-1984 Infection in Salivary Glands Polic, Stipan Jonjic, and Ulrich H. Koszinowski Human Antibodies Recognize Multiple Distinct Type-Specific Nobuo Yaegashi, Steven A. 2008-2019 and Cross-Reactive Regions of the Minor Capsid Proteins of Jenison, Maneesh Batra, and Human Papillomavirus Types 6 and 11 Denise A. Galloway Stimulation of Lymphokines in Jurkat Cells Persistently Kathleen A. Stellrecht, Kirk 2046-2050 Infected with Vaccinia Virus Sperber, and Beatriz G.-T. Pogo Activation of the Human Immunodeficiency Virus Type 1 Kathleen A. Stellrecht, Kirk 2051-2056 Long Terminal Repeat by Vaccinia Virus Sperber, and Beatriz G.-T. Pogo Complex Determinants of Macrophage Tropism in env of Kazuyasu Mori, Douglas J. 2067-2075 Simian Immunodeficiency Virus Ringler, Toshiaki Kodama, and Ronald C. Desrosiers High-Level Expression of the Tick-Borne Encephalitis Virus S. C. Jacobs, J. R. Stephenson, 2086-2095 NS1 Protein by Using an Adenovirus-Based Vector: and G. W. G. Wilkinson Protection Elicited in a Murine Model Biochemical and Physical Properties of the Prion Protein Richard A. Bessen and Richard F. 2096-2101 from Two Strains of the Transmissible Mink Marsh Encephalopathy Agent Human Cytotoxic T Cells Stimulated by Antigen on Anne H. Cherrie, Kevin Anderson, 2102-2110 Dendritic Cells Recognize the N, SH, F, M, 22K, and lb Gail W. Wertz, and Peter J. M. Proteins of Respiratory Syncytial Virus Openshaw Effects of Hydrostatic Pressure on a Membrane-Enveloped Jerson L. Silva, Peng Luan, 2111-2117 Virus: High Immunogenicity of the Pressure-Inactivated Michael Glaser, Edward W. Voss, Virus and Gregorio Weber Rapid In Vivo Reactivation of Herpes Simplex Virus in N. M. Sawtell and R. L. 2150-2156 Latently Infected Murine Ganglionic Neurons after Thompson Transient Hyperthermia Herpes Simplex Virus Type 1 Latency-Associated N. M. Sawtell and R. L. 2157-2169 Transcription Unit Promotes Anatomical Site-Dependent Thompson Establishment and Reactivation from Latency Cross-Reactive and Serotype-Specific Antibodies against T. R. Doel, C. M. F. A. Doel, 2187-2194 Foot-and-Mouth Disease Virus Generated by Different R. F. Staple, and R. DiMarchi Regions of the Same Synthetic Peptide Induction of Interleukin-1 and Tumor Necrosis Factor Jean E. Merrill, Yoshio Koyanagi, 2217-2225 Alpha in Brain Cultures by Human Immunodeficiency Virus Jerome Zack, Lisa Thomas, Type 1 Fredricka Martin, and Irvin S. Y. Chen Vaccinia Virus-Specific Human CD4+ Cytotoxic Rebecca A. Littaua, Akira Takeda, 2274-2280 T-Lymphocyte Clones John Cruz, and Francis A. Ennis Glycoprotein gI of Pseudorabies Virus Promotes Cell Fusion Laszlo Zsak, Federico 2316-2325 and Virus Spread via Direct Cell-to-Cell Transmission Zuckermann, Nancy Sugg, and Tamar Ben-Porat Susceptibility of Inbred Strains of Mice to Murine AIDS Ming Huang, Carole Simard, and 2398-2406 (MAIDS) Correlates with Target Cell Expansion and High Paul Jolicoeur Expression of Defective MAIDS Virus

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Efficacy of Oral Administration of Live Herpes Simplex Hiroshi Irie, Yusuke Harada, 2428-2434 Virus Type 1 as a Vaccine Motoyuki Kataoka, Masahiro Nagamuta, Yoichiro Moriya, Mitsuaki Handa, Motoo Saito, Shuzou Matsubara, Kana Kojima, and Yutaka Sugawara Multiple Isolates and Characteristics of Human T-Cell William W. Hall, Hidehiro 2456-2463 Leukemia Virus Type II Takahashi, Chunren Liu, Mark H. Kaplan, Olaf Scheewind, Shinji Ijichi, Kazuo Nagashima, and Robert C. Gallo Influence of Carbohydrate Moieties on the Immunogenicity Abdelaziz Benjouad, Jean-Claude 2473-2483 of Human Immunodeficiency Virus Type 1 Recombinant Gluckman, Herve Rochat, Luc gpl60 Montagnier, and Elmostafa Bahraoui Characterization of Dexamethasone-Induced Reactivation of D. Rock, J. Lokensgard, T. Lewis, 2484-2490 Latent Bovine Herpesvirus 1 and G. Kutish Expression of Herpes Simplex Virus Type 1 Glycoprotein I Homayon Ghiasi, Ravi Kaiwar, 2505-2509 in Baculovirus: Preliminary Biochemical Characterization Anthony B. Nesburn, and Steven and Protection Studies L. Wechsler Mechanism of Interferon Action: Alpha and Gamma Daniel C. Thomis and Charles E. 2519-2522 Interferons Differentially Affect mRNA Levels of the Samuel Catalytic Subunit of Protein Kinase A and Protein Mx in Human Cells A Chimeric Poliovirus/CD4 Receptor Confers Susceptibility Hans-Christoph Selinka, Andree 2523-2526 to Poliovirus on Mouse Cells Zibert, and Eckard Wimmer Diversity of T-Cell Receptors in Virus-Specific Cytotoxic T Yusuke Yanagi, Antoinette Tishon, 2527-2531 Lymphocytes Recognizing Three Distinct Viral Epitopes Hanna Lewicki, Beatrice A. Restricted by a Single Major Histocompatibility Complex Cubitt, and Michael B. A. Molecule Oldstone Generation of "Natural Killer Cell-Escape" Variants of Mauricio Vargas-Cortes, Carey L. 2532-2535 Pichinde Virus during Acute and Persistent Infections O'Donnell, Joseph W. Maciaszek, and Raymond M. Welsh Autopresentation of Virus Envelope by Carlo Ferrari, Massimo Pilli, 2536-2540 T Cells Amalia Penna, Antonio Bertoletti, Antonietta Valli, Albertina Cavalli, Giancarlo Pasetti, and Franco Fiaccadori A Cluster of Dispensable Genes within the Human Thomas R. Jones and Viera P. 2541-2546 Cytomegalovirus Genome Short Component: IRS1, US1 Muzithras through US5, and the US6 Family Human Immunodeficiency Virus Type 1 Major Neutralizing K. Schlienger, M. Mancini, Y. 2570-2576 Determinant Exposed on Hepatitis B Surface Antigen Riviere, D. Dormont, P. Tiollais, Particles Is Highly Immunogenic in Primates and M.-L. Michel JOURNAL OF VIROLOGY

Volume 66 May 1992 No. 5

ANIMAL VIRUSES Expression of the Marek's Disease Virus (MDV) Homolog of Masahiro Niikura, Yoshiharu 2631-2638 Glycoprotein B of Herpes Simplex Virus by a Recombinant Matsuura, Daiji Endoh, Misao Baculovirus and Its Identification as the B Antigen (gplOO, Onuma, and Takeshi Mikami gp6O, gp49) of MDV Bovine Immunodeficiency-Like Virus Encodes Factors Luke A. Pallansch, Carol S. 2647-2652 Which trans Activate the Long Terminal Repeat Lackman-Smith, and Matthew A. Gonda Identification and Characterization of the Herpes Simplex David S. McNabb and Richard J. 2653-2663 Virus Type 1 Virion Protein Encoded by the UL35 Open Courtney Reading Frame Association of ICPO but Not ICP27 with Purified Virions of Feng Yao and Richard J. Courtney 2709-2716 Herpes Simplex Virus Type 1 The Vaccinia Virus BlR Gene Product Is a Siqi Lin, Wen Chen, and Steven S. 2717-2723 Serine/Threonine Protein Kinase Broyles Nucleotide 880 Splice Donor Site Required for Efficient Narasimhaswamy S. Belaguli, 2724-2730 Transformation and RNA Accumulation by Human Mary M. Pater, and Alan Pater Papillomavirus Type 16 E7 Gene Structural and Functional Characterization of the Poliovirus Kurt Bienz, Denise Egger, Thomas 2740-2747 Replication Complex Pfister, and Monica Troxler Stable Rescue of a Glycoprotein gII Deletion Mutant of Annegret Kopp and Thomas C. 2754-2762 Pseudorabies Virus by Glycoprotein gI of Bovine Mettenleiter Herpesvirus 1 Immediate-Early RNA 2.9 and Early RNA 2.6 of Bovine Urs V. Wirtht Cornel Fraefel, 2763-2772 Herpesvirus 1 Are 3' Coterminal and Encode a Putative Bernd Vogt, Cestmir Vlcek, Zinc Finger Transactivator Protein Vaclav Paces, and Martin Schwyzer Formation of Heterotrimers between the Carola Schmidt, Jurgen Grunberg, 2792-2797 Membrane-Integrated and the Soluble Glycoproteins of and Joachim Kruppa Vesicular Stomatitis Virus Leads to Their Intracellular Cotransport A Second Origin of DNA Plus-Strand Synthesis Is Required Pierre Chameau, Marc Alizon, and 2814-2820 for Optimal Human Immunodeficiency Virus Replication Frangois Clavel Duck Hepatitis B Virus Infection of Hepatocytes Is Not Richard James Rigg and Heinz 2829-2836 Dependent on Low pH Schaller Regulation of the Epstein-Barr Virus DNA Polymerase Gene Frank B. Furnari, Melissa D. 2837-2845 Adams, and Joseph S. Pagano Identification of Critical cis Elements Involved in Mediating Xian W. Jin and Samuel H. Speck 2846-2852 Epstein-Barr Virus Nuclear Antigen 2-Dependent Activity of an Enhancer Located Upstream of the Viral BamHI C Promoter Functional Study of Hepatitis Delta Virus Large Antigen in Pei-Jer Chen, Fu-Lin Chang, 2853-2859 Packaging and Replication Inhibition: Role of the Chuan-Jen Wang, Chien-Ju Lin, Amino-Terminal Leucine Zipper Shian-Ying Sung, and Ding-Shinn Chen Use of Second-Site Homologous Recombination To Blake Tomkinson and Elliott Kieff 2893-2903 Demonstrate That Epstein-Barr Virus Nuclear Protein 3B Is Not Important for Lymphocyte Infection or Growth Transformation In Vitro

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Herpes Simplex Virus Type 1 ICPO Regulates Expression of Weizhong Cai and Priscilla A. 2904-2915 Immediate-Early, Early, and Late Genes in Productively Schaffer Infected Cells Herpes Simplex Viruses with Mutations in the Gene Jianxing Chen and Saul Silverstein 2916-2927 Encoding ICPO Are Defective in Gene Expression Regulated Expression of Foreign Genes in Vaccinia Virus William A. Alexander, Bernard 2934-2942 under the Control of Bacteriophage T7 RNA Polymerase Moss, and Thomas R. Fuerst and the Escherichia coli lac Repressor Relationship of Eukaryotic Initiation Factor 3 to Elizabeth E. Wyckoff, Richard E. 2943-2951 Poliovirus-Induced p220 Cleavage Activity Lloyd, and Ellie Ehrenfeld Viral and Host Cellular Transcription in Autographa David Guzo, Harold Rathburn, 2966-2972 californica Nuclear Polyhedrosis Virus-Infected Gypsy Moth Kim Guthrie, and Edward Cell Lines Dougherty Effect of Genomic Location on Expression of Sheryl A. Goodart, John F. 2973-2981 13-Galactosidase mRNA Controlled by the Herpes Simplex Guzowski, Marcia K. Rice, and Virus Type 1 UL38 Promoter Edward K. Wagner Ternary Complex Formation by Vaccinia Virus RNA Jeremiah Hagler and Stewart 2982-2989 Polymerase at an Early Viral Promoter: Analysis by Native Shuman Gel Electrophoresis Characterization of a 7-Kilodalton Subunit of Vaccinia Virus Bernard Y. Amegadzie, 3003-3010 DNA-Dependent RNA Polymerase with Structural Byung-Yoon Ahn, and Bernard Similarities to the Smallest Subunit of Eukaryotic RNA Moss Polymerase II Conserved Nucleotides in the TAR RNA Stem of Human Ulrike Delling, Lorne S. Reid, 3018-3025 Immunodeficiency Virus Type 1 Are Critical for Tat Binding Richard W. Barnett, Michael Y.-X. and trans Activation: Model for TAR RNA Tertiary Ma, Shane Climie, Martin Structure Sumner-Smith, and Nahum Sonenberg Identification and Characterization of Pseudorabies Virus Barbara G. Klupp, Nico Visser, 3048-3055 Glycoprotein H and Thomas C. Mettenleiter Expression of Aleutian Mink Disease Parvovirus Capsid Dahn L. Clemens, James B. 3077-3085 Proteins by a Recombinant Vaccinia Virus: Self-Assembly of Wolfinbarger, Shiro Mori, Bradley Capsid Proteins into Particles D. Berry, Stanley F. Hayes, and Marshall E. Bloom Characterization of Hepatitis B Virus Capsid Particle Siliang Zhou, Shu Qing Yang, and 3086-3092 Assembly in Xenopus Oocytes David N. Standring 5-Azacytidine and RNA Secondary Structure Increase the Vinay K. Pathak and Howard M. 3093-3100 Retrovirus Mutation Rate Temin Defective Synthesis of Early Region 4 mRNAs during David Ross and Edward Ziff 3110-3117 Abortive Adenovirus Infections in Monkey Cells Mapping Genetic Determinants for Human William A. O'Brien, Irvin S. Y. 3125-3130 Immunodeficiency Virus Type 1 Resistance to Soluble CD4 Chen, David D. Ho, and Eric S. Daar Poliovirus Chimeras Expressing Sequences from the Jean-Fran,ois Dedieu, Jorge 3161-3167 Principal Neutralization Domain of Human Ronco, Sylvie van der Werf, James Immunodeficiency Virus Type 1 M. Hogle, Yvette Henin, and Marc Girard Evidence for Zinc Binding by Two Structural Proteins of C. Joel Funk and Richard A. 3168-3171 Plodia interpunctella Granulosis Virus Consigli Human Papillomavirus Type 33 in a Tonsillar Carcinoma Peter J. F. Snijders, Adriaan J. C. 3172-3178 Generates Its Putative E7 mRNA via Two E6* Transcript van den Brule, Henri F. J. Species Which Are Terminated at Different Early Region Schrijnemakers, Petra M. C. Poly(A) Sites Raaphorst, Chris J. L. M. Meijer, and Jan M. M. Walboomers

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Reverse Transcriptase of Human Immunodeficiency Virus Zdenek Hostomsky, Zuzana 3179-3182 Type 1: Functionality of Subunits of the Heterodimer in Hostomska, Tie-Bo Fu, and John DNA Synthesis Taylor A Block in Release of Progeny Virus and a High Martha Brown, Heather L. 3198-3205 Particle-to-Infectious Unit Ratio Contribute to Poor Growth Wilson-Friesen, and Frances of Enteric Adenovirus Types 40 and 41 in Doane Crossover Site Selection during Recombination of Huy Khang Vu, Louis Delbecchi, 3210-3213 Polyomavirus Replicons Manon Quevillon, Elizabeth Herring-Gillam, and Pierre Bourgaux A Selectable Marker Allows Investigation of a Andrew Marchini, Jeffrey I. 3214-3219 Nontransforming Epstein-Barr Virus Mutant Cohen, Fred Wang, and Elliott Kieff Expression and Extracellular Release of Human Monique Royer, Saw-See Hong, 3230-3235 Immunodeficiency Virus Type 1 Gag Precursors by Bernard Gay, Martine Cerutti, and Recombinant Baculovirus-Infected Cells Pierre Boulanger Transactivation of Human Immunodeficiency Virus Type 1 Ann Hwee Lee, Ki Jeong Lee, 3236-3240 Long Terminal Repeat-Directed Gene Expression by the Sunyoung Kim, and Young Chul Human Foamy Virus bell Protein Requires a Specific DNA Sung Sequence Functional Analysis of the True Late Human Alison S. Depto and Richard M. 3241-3246 Cytomegalovirus pp28 Upstream Promoter: cis-Acting Stenberg Elements and Viral trans-Acting Proteins Necessary for Promoter Activation

VIRUS-CELL INTERACTIONS Molecular and Expression of a Murine Homolog of Mary E. Morrison and Vincent R. 2807-2813 the Human Poliovirus Receptor Gene Racaniello Transformation-Dependent Expression of Interleukin Genes S. J. Russell, A. Brandenburger, 2821-2828 Delivered by a Recombinant Parvovirus C. L. Flemming, M. K. L. Collins, and J. Rommelaere Driving Adenovirus Type 12-Transformed BALB/c Mouse Silvia Soddu and Andrew M. 2875-2884 Cells To Express High Levels of Class I Major Lewis, Jr. Histocompatibility Complex Proteins Enhances, Rather Than Abrogates, Their Tumorigenicity Modification of Some Biological Properties of HeLa Cells Christian Walz and Jorg R. 2990-3002 Containing Adeno-Associated Virus DNA Integrated into Schlehofer 17 Spleen Necrosis Virus, an Avian Immunosuppressive Vineet N. KewalRamani, Antonito 3026-3031 Retrovirus, Shares a Receptor with the Type D Simian T. Panganiban, and Michael Emerman Infection of HeLa Cells with Poliovirus Results in Sheryl J. Rubinstein, Thomas 3062-3068 Modification of a Complex That Binds to the rRNA Hammerle, Eckard Wimmer, and Promoter Asim Dasgupta Specific Interactions of HeLa Cell Proteins with Proposed John R. Gebhard and Ellie 3101-3109 Translation Domains of the Poliovirus 5' Noncoding Region Ehrenfeld Nuclear Factor I Is Specifically Targeted to Discrete Julia Bosher, Angela Dawson, and 3140-3150 Subnuclear Sites in Adenovirus Type 2-Infected Cells Ronald T. Hay Theiler's Virus Replication in Brain Macrophages Cultured Martine Levy, Christine Aubert, 3188-3193 In Vitro and Michel Brahic Replication of Plasmid-Derived Human Papillomavirus Type Salvatore Mungal, Bettie M. 3220-3224 11 DNA in Cultured Keratinocytes Steinberg, and Lome B. Taichman Nuclear Entry and Nucleolar Localization of the Newcastle Mark E. Peeples, Can Wang, 3263-3269 Disease Virus (NDV) Matrix Protein Occur Early in Kailash C. Gupta, and Natalie Infection and Do Not Require Other NDV Proteins Coleman

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VIRAL AND CELLULAR ONCOGENES Mutations within the 5' Half of the Avian Retrovirus MC29 Steven F. Farina, Janice L. Huff, 2698-2708 v-myc Gene Alter or Abolish Transformation of Chicken and J. Thomas Parsons Embryo Fibroblasts and Macrophages Transformation of a Continuous Rat Embryo Fibroblast Cell Jiyue Zhu, Philip W. Rice, Lisa 2780-2791 Line Requires Three Separate Domains of Simian Virus 40 Gorsch, Marina Abate, and Large T Antigen Charles N. Cole Insertional Mutagenesis offlvi-2 in Tumors Induced by Laura S. Levy and Patricia A. 2885-2892 Infection with LC-FeLV, a myc-Containing Strain of Feline Lobelle-Rich Leukemia Virus Transactivation of Erythroid GATA-1 Rosemarie E. Aurigemma, Donald 3056-3061 by a myb-ets-Containing Retrovirus G. Blair, and Sandra K. Ruscetti

BACTERIAL VIRUSES Heterologous Recombination in the Double-Stranded RNA Leonard Mindich, Xueying Qiao, 2605-2610 Bacteriophage +6 Shiroh Onodera, Paul Gottlieb, and Jeffrey Strassman In Vitro Packaging and Replication of Individual Genomic Paul Gottlieb, Jeffrey Strassman, 2611-2616 Segments of Bacteriophage +6 RNA Xueying Qiao, Mikko Frilander, Avra Frucht, and Leonard Mindich The Insertion Site of the Temperate Phage HB-746 Is Alicia Romero, Rubens Lopez, and 2860-2864 Located near the Phage Remnant in the Pneumococcal Host Pedro Garcia Chromosome

PLANT VIRUSES Coding Capacity Determines In Vivo Accumulation of a K. Andrew White, J. B. Bancroft, 3069-3076 Defective RNA of Clover Yellow Mosaic Virus and George A. Mackie The Full-Length Transcript of a Caulimovirus Is a Herman B. Scholthof, Siddarame 3131-3139 Polycistronic mRNA Whose Genes Are trans Activated by Gowda, Fang C. Wu, and Robert the Product of Gene VI J. Shepherd VIRAL PATHOGENESIS AND IMMUNITY Sickness and Recovery of Dogs Challenged with a Street Makonnen Fekadu, John W. 2601-2604 Rabies Virus after Vaccination with a Vaccinia Virus Sumner, John H. Shaddock, Dane Recombinant Expressing Rabies Virus N Protein W. Sanderlin, and George M. Baer Molecular Attenuation of Vaccinia Virus: Mutant Moon Soo Lee, J. Michael Roos, 2617-2630 Generation and Animal Characterization Laura C. McGuigan, Kenneth A. Smith, Nancy Cormier, Lawrence K. Cohen, Bryan E. Roberts, and Lendon G. Payne tsl, a Temperature-Sensitive Mutant of Moloney Murine Kunal Saha and P. K. Y. Wong 2639-2646 Leukemia Virus TB, Can Infect both CD4+ and CD8+ T Cells but Requires CD4+ T Cells in Order To Cause Paralysis and Immunodeficiency Specific Lysis of Targets Expressing Varicella-Zoster Virus Z. Huang, A. Vafai, J. Lee, R. 2664-2669 gpl or gplV by CD4+ Human T-Cell Clones Mahalingam, and A. R. Hayward Hepatitis B Virus (HBV)-Specific Cytotoxic T-Cell Response Stephane Guilhot, Patricia Fowler, 2670-2678 in Humans: Production of Target Cells by Stable Expression Gloria Portillo, Robert F. of HBV-Encoded Proteins in Immortalized Human B-Cell Margolskee, Carlo Ferrari, Antonio Lines Bertoletti, and Francis V. Chisari Ovine Lentivirus Is Macrophagetropic and Does Not Mark D. Gorrell, Malcolm R. 2679-2688 Replicate Productively in T Lymphocytes Brandon, Darlene Sheffer, Robert J. Adams, and Opendra Narayan

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Epstein-Barr Virus Latent Gene Transcription in L. Brooks, Q. Y. Yao, A. B. 2689-2697 Cells: Coexpression of EBNA1, Rickinson, and L. S. Young LMP1, and LMP2 Transcripts Human Immunodeficiency Virus Vectors for Inducible Gary L. Buchschacher, Jr., and 2731-2739 Expression of Foreign Genes Antonito T. Panganiban Recombinant Vaccine for Canine Parvovirus in Dogs Jose Angel L6pez de Turiso, Elena 2748-2753 Cortes, Concepci6n Martinez, Rocio Ruiz de Ybaiiez, Isabel Simarro, Carmen Vela, and Ignacio Casal Establishment and Functional Characterization of Human Yoshihiro Yakushijin, Masaki 2773-2779 Herpesvirus 6-Specific CD4+ Human T-Cell Clones Yasukawa, and Yuzuru Kobayashi Molecular Characterization of a Neuropathogenic and Michiaki Masuda, Mary P. 2798-2806 Nonerythroleukemogenic Variant of Friend Murine Remington, Paul M. Hoffman, Leukemia Virus PVC-211 and Sandra K. Ruscetti Hemagglutinin-Esterase-Specific Monoclonal Antibodies Kyoko Yokomori, Susan C. Baker, 2865-2874 Alter the Neuropathogenicity of Mouse Hepatitis Virus Stephen A. Stohlman, and Michael M. C. Lai Target Epitope in the Tax Protein of Human T-Cell Mari Kannagi, Hisatoshi Shida, 2928-2933 Leukemia Virus Type I Recognized by Class I Major Hisanaga Igarashi, Kazuo Kuruma, Histocompatibility Complex-Restricted Cytotoxic T Cells Hitoshi Murai, Yuko Aono, Ikuro Maruyama, Mitsuhiro Osame, Toshio Hattori, Hidetoshi Inoko, and Shinji Harada Cytotoxicity of a Replication-Defective Mutant of Herpes Paul A. Johnson, Atsushi 2952-2965 Simplex Virus Type 1 Miyanohara, Fred Levine, Tim Cahill, and Theodore Friedmann An Early Event in Murine Cytomegalovirus Replication Ann E. Campbell, Jacquelyn S. 3011-3017 Inhibits Presentation of Cellular Antigens to Cytotoxic T Slater, Victoria J. Cavanaugh, and Lymphocytes Richard M. Stenberg Pseudorabies Virus Envelope Glycoprotein gI Influences J. P. Card, M. E. Whealy, A. K. 3032-3041 both Neurotropism and Virulence during Infection of the Robbins, and L. W. Enquist Rat Visual System Identification of T-Helper Epitopes in the VP1 Capsid M. Kutubuddin, J. Simons, and M. 3042-3047 Protein of Poliovirus Chow The Pathogenesis of Infection with Minute Virus of Mice David G. Brownstein, Abigail L. 3118-3124 Depends on Expression of the Small Nonstructural Protein Smith, Elizabeth A. Johnson, NS2 and on the Genotype of the Allotropic Determinants David J. Pintel, Lisa Kay Naeger, VP1 and VP2 and Peter Tattersall Mutation of Human Immunodeficiency Virus Type 1 at Li Chen Dai, Kim West, Rebecca 3151-3154 Amino Acid 585 on gp41 Results in Loss of Killing by CD8+ Littaua, Kazuo Takahashi, and A24-Restricted Cytotoxic T Lymphocytes Francis A. Ennis Viral Infection of the Thymus Chwan-Chuen King, Beth D. 3155-3160 Jamieson, Kiran Reddy, Neeraj Bali, Rita J. Concepcion, and Rafi Ahmed -Associated Sequence Variation in the Third Ron A. M. Fouchier, Martijn 3183-3187 Variable Domain of the Human Immunodeficiency Virus Groenink, Neeltje A. Kootstra, Type 1 gp120 Molecule Matthijs Tersmette, Han G. Huisman, Frank Miedema, and Hanneke Schuitemaker A Mutation Present in the Amino Terminus of Sabin 3 Joanne M. Tatem, Carolyn 3194-3197 Poliovirus VP1 Protein Is Attenuating Weeks-Levy, Alice Georgiu, Susan J. DiMichele, Edward J. Gorgacz, Vincent R. Racaniello, Francis R. Cano, and Steven J. Mento

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Human Herpesvirus 7 Is a Constitutive Inhabitant of Adult Linda S. Wyatt and Niza Frenkel 3206-3209 Human Saliva Virus (HCV) Circulates as a Population of Maria Martell, Juan I. Esteban, 3225-3229 Different but Closel Related : Quasispecies Nature Josep Quer, Joan Genesca, Amy of HCV Genome Distribution Weiner, Rafael Esteban, Jaume Guardia, and Jordi Gomez Transmembrane Protein Oligomers of Caprine Travis C. McGuire, Donald P. 3247-3250 Arthritis-Encephalitis Lentivirus Are Immunodominant in Knowles, Jr., William C. Davis, Goats with Progressive Arthritis Alberta L. Brassfield, Theresa A. Stem, and William P. Cheevers Cytolytic T Lymphocytes Specific for Tumors and Infected Jennifer G. Erbe, Kathy A. Green, 3251-3256 Cells from Mice with a Retrovirus-Induced Karen M. Crassi, Herbert C. Immunodeficiency Syndrome Morse III, and William R. Green Consistent Transcription of the Epstein-Barr Virus LMP2 Pierre Busson, Rachel McCoy, 3257-3262 Gene in Nasopharyngeal Carcinoma Robert Sadler, Kevin Gilligan, Thomas Tursz, and Nancy Raab-Traub JOURNAL OF VIROLOGY

Volume 66 June 1992 No. 6

ANIMAL VIRUSES Effects of Deletions in the Cytoplasmic Domain on Biological Dana H. Gabuzda, Andrew Lever, 3306-3315 Functions of Human Immunodeficiency Virus Type 1 Ernest Terwilliger, and Joseph Envelope Glycoproteins Sodroski A Structural Polypeptide of the Baculovirus Autographa Marc Whitford and Peter Faulkner 3324-3329 californica Nuclear Polyhedrosis Virus Contains O-Linked N-Acetylglucosamine Determinants of Substrate Recognition by Poliovirus 2A Christopher U. T. Hellen, 3330-3338 Proteinase Chong-Kyo Lee, and Eckard Wimmer Mechanism of Coronavirus Transcription: Duration of Yong Seok Jeong and Shinji 3339-3346 Primary Transcription Initiation Activity and Effects of Makino Subgenomic RNA Transcription on RNA Replication Simian Virus 40 T Antigen Activates the Late Promoter by Evelyne May, Francis Omilli, 3347-3354 Modulating the Activity of Negative Regulatory Elements Janine Borde, and Patrick Scieller Binding of EBNA-1 to DNA Creates a Protease-Resistant Waris A. Shah, Richard F. 3355-3362 Domain That Encompasses the DNA Recognition and Ambinder, Gary S. Hayward, and Dimerization Functions S. Diane Hayward Interaction of Rotavirus Particles with Liposomes P. Nandi, A. Charpilienne, and J. 3363-3367 Cohen Boundaries and Structure of Human Cytomegalovirus David G. Anders, Marilyn A. 3373-3384 oriLyt, a Complex Origin for Lytic-Phase DNA Replication Kacica, Gregory Pari, and Suzanne M. Punturieri Appropriate In Vivo Expression of a Muscle-Specific Christos J. Petropoulos, William 3391-3397 Promoter by Using Avian Retroviral Vectors for Gene Payne, Donald W. Salter, and Transfer Stephen H. Hughes Two Amino Acid Substitutions within the Capsid Are Lisa J. Ball-Goodrich and Peter 3415-3423 Coordinately Required for Acquisition of Fibrotropism by Tattersall the Lymphotropic Strain of Minute Virus of Mice Equine Infectious Anemia Virus Gene Expression: R. Louis Schiltz, Ding S. Shih, 3455-3465 Characterization of the RNA Splicing Pattern and the Siyamak Rasty, Ronald C. Protein Products Encoded by Open Reading Frames S1 Montelaro, and Keith E. Rushlow and S2 Mutations within the env Gene of Mason-Pfizer Monkey Brian A. Brody and Eric Hunter 3466-3475 Virus: Effects on Protein Transport and SU-TM Association Late Promoter of Human Papillomavirus Type 8 and Its Frank Stubenrauch, Jacek 3485-3493 Regulation Malejczyk, Pawel G. Fuchs, and Herbert Pfister Conformational Alteration of Sindbis Virion Glycoproteins William J. Meyer, Susan Gidwitz, 3504-3513 Induced by Heat, Reducing Agents, or Low pH Virginia K. Ayers, Randal J. Schoepp, and Robert E. Johnston Role of N-Linked Oligosaccharides in Processing and Zhiyong Qiu, Tom C. Hobman, 3514-3521 Intracellular Transport of E2 Glycoprotein of Rubella Virus Helen L. McDonald, Nina 0. L. Seto, and Shirley Gillam Identification and Characterization of a Coronavirus Jennifer A. Fosmire, Kyongmin 3522-3530 Packaging Signal Hwang, and Shinji Makino

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Transient Expression and Mutational Analysis of the John A. Taylor, Janice C. Meyer, 3566-3572 Rotavirus Intracellular Receptor: the C-Terminal Margaret A. Legge, Judith A. Methionine Residue Is Essential for Ligand Binding O'Brien, Jeanette E. Street, Vivienne J. Lord, Cornelia C. Bergmann, and A. Richard Bellamy Localization of cis-Acting Sequence Requirements in the Adrian H. Batchelor and Peter 3573-3582 Promoter of the Latency-Associated Transcript of Herpes O'Hare Simplex Virus Type 1 Required for Cell-Type-Specific Activity Human Immunodeficiency Virus Type 1 Integration Protein: Paula A. Sherman, Matthew L. 3593-3601 DNA Sequence Requirements for Cleaving and Joining Dickson, and James A. Fyfe Reactions Structural and Functional Analysis of the Visna Virus Laurence S. Tiley and Bryan R. 3609-3615 Rev-Response Element Cullen The Herpes Simplex Virus 1 RNA Binding Protein Usll Is a Richard J. Roller and Bernard 3624-3632 Virion Component and Associates with Ribosomal 60S Roizman Subunits The 11,600-Mw Protein Encoded by Region E3 of Ann E. Tollefson, Abraham Scaria, 3633-3642 Adenovirus Is Expressed Early but Is Greatly Amplified Sankar K. Saha, and William S. M. at Late Stages of Infection Wold Receptor Properties of Two Varicella-Zoster Virus Virginia Litwin, Wallen Jackson, 3643-3651 Glycoproteins, gpl and gpIV, Homologous to Herpes and Charles Grose Simplex Virus gE and gI Direct Determination of the Point Mutation Rate of a Raymond J. Monk, Frank G. 3683-3689 Murine Retrovirus Malik, David Stokesberry, and Leonard H. Evans Transcription from Varicella-Zoster Virus Gene 67 Paul Ling, Paul R. Kinchington, 3690-3698 (Glycoprotein IV) Majid Sadeghi-Zadeh, William T. Ruyechan, and John Hay A Specific Sequence with a Bulged Guanosine Residue(s) in Steven M. Holland, Margarita 3699-3706 a Stem-Bulge-Stem Structure of Rev-Responsive Element Chavez, Susan Gerstberger, and RNA Is Required for trans Activation by Human Sundararajan Venkatesan Immunodeficiency Virus Type 1 Rev A New Retrovirus Packaging Cell for Gene Transfer Yoshiyuki Takahara, Kumiko 3725-3732 Constructed from Amplified Long Terminal Repeat-Free Hamada, and David E. Housman Chimeric Proviral Genes Regulation of Delayed-Early Gene Transcription by Dual Linda A. Guarino and Melinda 3733-3739 TATA Boxes Smith Determination of the Poliovirus RNA Polymerase Error Carol D. Ward and James B. 3784-3793 Frequency at Eight Sites in the Viral Genome Flanegan Herpes Simplex Virus Infection Selectively Stimulates Joseph D. Mosca, Paula M. Pitha, 3811-3822 Accumulation of 18-Interferon Reporter Gene mRNA by a and Gary S. Hayward Posttranscriptional Mechanism Neutralization of Influenza Virus by Low Concentrations of S. J. Armstrong and N. J. 3823-3832 Hemagglutinin-Specific Polymeric Immunoglobulin A Dimmock Inhibits Viral Fusion Activity, but Activation of the Ribonucleoprotein Is also Inhibited Functional Diversity of ElA Gene Autoregulation among Joy D. Cogan, Stephen N. Jones, 3833-3845 Human Adenoviruses Robert K. Hall, and Clark Tibbetts Complementation Studies with Rous Sarcoma Virus gag and Suzanne Oertle, Neil Bowles, and 3873-3878 gag- Polyprotein Mutants Pierre-Francois Spahr Specific NF-KB Subunits Act in Concert with Tat To Jinsong Liu, Neil D. Perkins, 3883-3887 Stimulate Human Immunodeficiency Virus Type 1 Roland M. Schmid, and Gary J. Transcription Nabel

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Altered Cell Tropism and Cytopathicity of Feline Kenzo Tokunaga, Yoshii Nishino, 3893-3898 Immunodeficiency Viruses in Two Different Feline Hiroshi Oikawa, Chiaki Ishihara, CD4-Positive, CD8-Negative Cell Lines Takeshi Mikami, and Kazuyoshi Ikuta Characterization of Regulatory Functions of the Pascale Jackers, Patricia 3899-3903 Varicella-Zoster Virus Gene 63-Encoded Protein Defechereux, Laurence Baudoux, Charles Lambert, Marc Massaer, Marie-Paule Merville-Louis, Bernard Rentier, and Jacques Piette Gene for the Major Antigenic Structural Protein (pl00) of Frank Neipel, Klaus Ellinger, and 3918-3924 Human Herpesvirus 6 Bernhard Fleckenstein Synergistic Activation of the Human Immunodeficiency James Kamine and G. Chinnadurai 3932-3936 Virus Type 1 Promoter by the Viral Tat Protein and Cellular Transcription Factor Spl New Member of the Multigene Family of Complement Jens-Christian Albrecht and 3937-3940 Control Proteins in Herpesvirus Saimiri Bernhard Fleckenstein Mechanism of Action of the Papillomavirus E2 Repressor: James Barsoum, S. S. Prakash, 3941-3945 Repression in the Absence of DNA Binding Paula Han, and Elliot J. Androphy Activation of the Human Immunodeficiency Virus Type 1 David M. Markovitz, Mark C. 3961-3965 Enhancer Is Not Dependent on NFAT-1 Hannibal, Michael J. Smith, Ronald Cossman, and Gary J. Nabel Cytoplasmic Domain Truncation Enhances Fusion Activity Mark J. Mulligan, Galina V. 3971-3975 by the Exterior Glycoprotein Complex of Human Yamshchikov, G. Douglas Ritter, Immunodeficiency Virus Type 2 in Selected Cell Types Jr., Feng Gao, Mojun J. Jin, Clinton D. Nail, Claus Peter Spies, Beatrice H. Hahn, and Richard W. Compans

VIRUS-CELL INTERACTIONS Epstein-Barr Virus Enters B Cells and Epithelial Cells by Nancimae Miller and Lindsey M. 3409-3414 Different Routes Hutt-Fletcher Characterization of a Herpes Simplex Virus Sequence Which Louise McCormick, Richard J. 3435-3447 Binds a Cellular Protein as Either a Single-Stranded or Roller, and Bernard Roizman Double-Stranded DNA or RNA Reticuloendotheliosis Type C and Primate Type D Han-Mo Koo, Jie Gu, Alfredo 3448-3454 Oncoretroviruses Are Members of the Same Receptor Varela-Echavarria, Yacov Ron, Interference Group and Joseph P. Dougherty In Vitro Transactivation of Baculovirus Early Genes by Barbara Glocker, Richard R. 3476-3484 Nuclear Extracts from Autographa californica Nuclear Hoopes, Jr., and George F. Polyhedrosis Virus-Infected Spodoptera frugiperda Cells Rohrmann Differential Factor Binding at the Promoter of Early Ralf Krappa, Annett Behn-Krappa, 3494-3503 Baculovirus Gene PE38 during Viral Infection: GATA Motif Felicitas Jahnel, Walter Doerfler, Is Recognized by an Insect Protein and Dagmar Knebel-Morsdorf Human Immunodeficiency Virus Type 2 Infection and Paul R. Clapham, Aine McKnight, 3531-3537 Fusion of CD4-Negative Human Cell Lines: Induction and and Robin A. Weiss Enhancement by Soluble CD4 Herpes Simplex Virus Type 1-Mediated Induction of Human Jaromir Vlach and Paula M. Pitha 3616-3623 Immunodeficiency Virus Type 1 Provirus Correlates with Binding of Nuclear Proteins to the NF-ucB Enhancer and Leader Sequence Identification of a Putative Receptor for Subgroup A Feline Ananta K. Ghosh, Michael H. 3707-3714 Leukemia Virus on Feline T Cells Bachmann, Edward A. Hoover, and James I. Mullins

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Epstein-Barr Virus Latent Gene Expression in Uncultured Lirong Qu and David T. Rowe 3715-3724 Peripheral Blood Lymphocytes Two API Sites Binding JunB Are Essential for Human Franc,oise Thierry, Giannis Spyrou, 3740-3748 Papillomavirus Type 18 Transcription in Keratinocytes Moshe Yaniv, and Peter Howley p105, the NF-KB p50 Precursor Protein, Is One of the Anthony J. Capobianco, David 3758-3767 Cellular Proteins Complexed with the v-Rel Oncoprotein in Chang, George Mosialos, and Transformed Chicken Spleen Cells Thomas D. Gilmore The GC Box and TATA Transcription Control Elements in Jeong K. Ahn, Zachary W. Pitluk, 3776-3783 the P38 Promoter of the Minute Virus of Mice Are and David C. Ward Necessary and Sufficient for Transactivation by the Nonstructural Protein NS1 A Cellular Function Is Required for Pseudorabies Virus M. E. Whealy, A. K. Robbins, F. 3803-3810 Envelope Glycoprotein Processing and Virus Egress Tufaro, and L. W. Enquist Glycoprotein H of Pseudorabies Virus Is Essential for Entry Ben Peeters, Niels de Wind, Rene 3888-3892 and Cell-to-Cell Spread of the Virus Broer, Arno Gielkens, and Rob Moormann Dual Regulation of Silent and Productive Infection in Peter Westervelt, Timothy Henkel, 3925-3931 Monocytes by Distinct Human Immunodeficiency Virus David B. Trowbridge, Jan Type 1 Determinants Orenstein, John Heuser, Howard E. Gendelman, and Lee Ratner The Bel-1 Protein of Human Foamy Virus Activates Human Andreas Keller, Elizabeth D. *3946-3949 Immunodeficiency Virus Type 1 Gene Expression via a Garrett, and Bryan R. Cullen Novel DNA Target Site VIRAL AND CELLULAR ONCOGENES

% Alterations of the p53 Gene in Nasopharyngeal Carcinoma P. Effert, R. McCoy, M. 3768-3775 Abdel-Hamid, K. Flynn, Q. Zhang, P. Busson, T. Tursz, E. Liu, and N. Raab-Traub Species-Specific Phosphorylation of Mouse and Rat p53 in Tilo Patschinsky, Uwe 3846-3859 Simian Virus 40-Transformed Cells Knippschild, and Wolfgang Deppert

PLANT VIRUSES A cDNA Clone of Tomato Mosaic Virus Is Infectious in Hans Weber, Petra Haeckel, and 3909-3912 Plants Artur J. P. Pfitzner

PROTOZOAN AND FUNGAL VIRUSES Ribosomal Frameshifting Efficiency and gagigag-pol Ratio Jonathan D. Dinman and Reed B. 3669-3676 Are Critical for Yeast M1 Double-Stranded RNA Virus Wickner Propagation

VIRAL PATHOGENESIS AND IMMUNITY Role and Specificity of T-Cell Subsets in Spontaneous Michael N. Robertson, Gerald J. 3271-3277 Recovery from Friend Virus-Induced Leukemia in Mice Spangrude, Kim Hasenkrug, Linda Perry, Jane Nishio, Kathy Wehrly, and Bruce Chesebro Organ- and Age-Specific Replication of Polyomavirus in Julia J. Wirth, Andrea Amalfitano, 3278-3286 Mice Robin Gross, Michael B. A. Oldstone, and Michele M. Fluck Enhancer Dependence of Polyomavirus Persistence in Mouse Rosemary Rochford, Juan P. 3287-3297 Kidneys Moreno, Meredith L. Peake, and Luis P. Villarreal

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Murine Retrovirus-Induced Spongiform Markus Czub, Frank J. McAtee, 3298-3305 Encephalomyelopathy: Host and Viral Factors Which and John L. Portis Determine the Length of the Incubation Period Preventive Effects of Early Anti-CD4 or Anti-CD8 Lothar Stitz, Martin Sobbe, and 3316-3323 Treatment on Borna Disease in Rats Thomas Bilzer Modification of Foot-and-Mouth Disease Virus 01 Caseros Elizabeth Rieder Rojas, Elisa 3368-3372 after Serial Passages in the Presence of Antiviral Polyclonal Carrillo, M6nica Schiappacassi, Sera and Rodolfo Campos Enhancement of the Antibody Response to Flavivirus B-Cell John T. Roehrig, Alison J. 3385-3390 Epitopes by Using Homologous or Heterologous T-Cell Johnson, Ann R. Hunt, Barry J. Epitopes Beaty, and James H. Mathews Efficacy of Inactivated Whole-Virus and Subunit Vaccines in C. J. Issel, D. W. Horohov, D. F. 3398-3408 Preventing Infection and Disease Caused by Equine Lea, W. V. Adams, Jr., S. D. Infectious Anemia Virus Hagius, J. M. McManus, A. C. Allison, and R. C. Montelaro Protection of Mice and Swine from Pseudorabies Virus Michel Riviere, James Tartaglia, 3424-3434 Conferred by Vaccinia Virus-Based Recombinants Marion E. Perkus, Elizabeth K. Norton, Cathy Molnar Bongermino, Francois Lacoste, Christiane Duret, Philippe Desmettre, and Enzo Paoletti Pathogenesis of Feline Leukemia Virus T17: Contrasting Anne Terry, Ruth Fulton, Monica 3538-3549 Fates of Helper, v-myc, and v-tcr Proviruses in Secondary Stewart, David E. Onions, and Tumors James C. Neil Derivation of Neurotropic Simian Immunodeficiency Virus D. P. Sharma, M. C. Zink, M. 3550-3556 from Exclusively Lymphocytetropic Parental Virus: Anderson, R. Adams, J. E. Pathogenesis of Infection in Macaques Clements, S. V. Joag, and 0. Narayan Evolution of the Capsid Protein Genes of Foot-and-Mouth M. A. Martinez, J. Dopazo, J. 3557-3565 Disease Virus: Antigenic Variation without Accumulation of Hernandez, M. G. Mateu, F. Amino Acid Substitutions over Six Decades Sobrino, E. Domingo, and N. J. Knowles Analysis of Murine Major Histocompatibility Complex Class A. B. Kulkarni, A. Mullbacher, 3583-3592 II-Restricted T-Cell Responses to the Flavivirus Kunjin by C. R. Parrish, E. G. Westaway, Using Vaccinia Virus Expression G. Coia, and R. V. Blanden Cross-Neutralization of Human Immunodeficiency Virus Marjorie Robert-Guroff, Kristine 3602-3608 Type 1 and 2 and Simian Immunodeficiency Virus Isolates Aldrich, Rebecca Muldoon, Theodore L. Stern, Geetha P. Bansal, Thomas J. Matthews, Phillip D. Markham, Robert C. Gallo, and Genoveffa Franchini Mutations in the env Gene of Friend Spleen Focus-Forming Manas K. Majumdar, Chung-Lung 3652-3660 Virus Overcome Fv-2'-Mediated Resistance to Friend Cho, Mary T. Fox, Kristine L. Virus-Induced Erythroleukemia Eckner, Sue Kozak, David Kabat, and Roy W. Geib Suppression of Virus-Specific Antibody Production by CD8+ Demetrius Moskophidis, Hanspeter 3661-3668 Class I-Restricted Antiviral Cytotoxic T Cells In Vivo Pircher, Ilja Ciernik, Bernhard Odermatt, Hans Hengartner, and Rolf M. Zinkernagel A Second Envelope Glycoprotein Meditaes Neutralization of Emilie Weiland, Reinhard Ahl, 3677-3682 a Pestivirus, Hog Cholera Virus Robert Stark, Frank Weiland, and Heinz-Jurgen Thiel Disulfide-Bonded Discontinuous Epitopes on the Pablo R. Grigera, Walter Keil, and 3749-3757 Glycoprotein of Vesicular Stomatitis Virus (New Jersey Robert R. Wagner Serotype)

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Cytomegalovirus Determinant of Replication in Salivary William C. Manning, Cheryl A. 3794-3802 Glands Stoddart, Laurel A. Lagenaur, Gerardo B. Abenes, and Edward S. Mocarski Amino Acid Sequence and Structural Properties of Protein Antonio Alcami, Ana Angulo, 3860-3868 p12, an African Swine Fever Virus Attachment Protein Carlos Lopez-Otin, Maribel Munioz, Jose M. P. Freije, Angel L. Carrascosa, and Eladio Vifnuela Comparison of the Sequence of the Gene Encoding African Ana Angulo, Eladio Vinluela, and 3869-3872 Swine Fever Virus Attachment Protein p12 from Field Virus Antonio Alcami Isolates and Viruses Passaged in Tissue Culture Genomic Variation and Segregation of Equine Infectious Carol H. Kim and James W. Casey 3879-3882 Anemia Virus during Acute Infection Efficient Production of Human Immunodeficiency Virus Paul Jolicoeur, Andre Laperriere, 3904-3908 Proteins in Transgenic Mice and Normand Beaulieu Predominant Use of a T-Cell Receptor V13 Gene Family in Zheng W. Chen, Hiroshi 3913-3917 Simian Immunodeficiency Virus Gag-Specific Cytotoxic T Yamamoto, David I. Watkins, Lymphocytes in a Rhesus Monkey Gene Levinson, and Norman L. Letvin Protection of Macaques against Infection with Simian Type Brian A. Brody, Eric Hunter, John 3950-3954 D Retrovirus (SRV-1) by Immunization with Recombinant D. Kluge, Rick Lasarow, Murray Vaccinia Virus Expressing the Envelope Glycoproteins of Gardner, and Preston A. Marx Either SRV-1 or Mason-Pfizer Monkey Virus (SRV-3) Tumor Necrosis Factor Alpha Negatively Regulates Hepatitis Patrick N. Gilles, Georg Fey, and 3955-3960 B Virus Gene Expression in Transgenic Mice Francis V. Chisari Differential Human Immunodeficiency Virus Expression in A. Chapel, A. Bensussan, E. 3966-3970 CD4+ Cloned Lymphocytes: from Viral Latency to Vilmer, and D. Dormont Replication ERRATUM Recombination between Feline Leukemia Virus Subgroup B Rakesh Pandey, Ananta K. Ghosh, 3976 or C and Endogenous env Elements Alters the In Vitro D. Vinod Kumar, Barbara A. Biological Activities of the Viruses Bachman, Darryl Shibata, and Pradip Roy-Burman AUTHORS' CORRECTIONS The Position of Heterologous Epitopes Inserted in Hepatitis Florian Schodel, Ann M. Moriarty, 3977 B Virus Core Particles Determines Their Immunogenicity Darrell L. Peterson, Jian Zheng, Janice L. Hughes, Hans Will, Didier J. Leturcq, Juli S. McGhee, and David R. Milich Turnip Yellow Mosaic Virus RNAs with Anticodon Loop Ching-Hsui Tsai and Theo W. 3977 Substitutions That Result in Decreased Valylation Fail To Dreher Replicate Efficiently