Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management Advances in Neurobiology

Advances in Neurobiology 24 M. Mohamed Essa M. Walid Qoron eh Editors Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management Advances in Neurobiology Volume 24 Series Editor Arne Schousboe, Department of Drug Design & Pharmacology, University of Copenhagen, Copenhagen, Denmark More information about this series at http://www.springer.com/series/8787 M. Mohamed Essa • M. Walid Qoronfleh Editors Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management Editors M. Mohamed Essa M. Walid Qoronfleh Food Science and Nutrition, CAMS World Innovation Summit for Health WISH Sultan Qaboos University Qatar Foundation Muscat, Oman Doha, Qatar ISSN 2190-5215 ISSN 2190-5223 (electronic) Advances in Neurobiology ISBN 978-3-030-30401-0 ISBN 978-3-030-30402-7 (eBook) https://doi.org/10.1007/978-3-030-30402-7 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland Foreword by Brian J. Wilkinson It is a great pleasure to write a foreword for the book Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management edited by Drs. Mohamed Essa and M. Walid Qoronfleh, who have gained extensive experience in their respec- tive scientific fields, including natural compounds and their potential beneficial effects on brain diseases and human health. It is highly commendable for these two scientists to author this book at this time when people are looking for something that would give them a good perspective on autism and the impact of food natural products on this disease spectrum. Nowadays, there is great interest in investigations of food ingredients for their potential health benefits among the people suffering from autism spectrum disorder (ASD). We frequently fail to recognize the real benefit of traditional medicines and food natural ingredients despite the fact that they have been used for many centuries and are still being used widely in all cultures across the globe. This book provides a compelling perspective on the potential benefits of many edible items, including natural compounds, herbs, vegetables, fruits, grains, seeds, and nuts, for which sub- stantial evidence now exist in the literature of their effectiveness against ASD. The individual chapters that are covered and written by experienced authors in their fields provide an additional value to the reader. The chapters are organized under three parts, covering the following: (1) Autism Spectrum Disorder from Background to Interplay of Genetic, Epigenetic, Environmental Risk Factors and Nutraceuticals, (2) Specific Foods and Nutrient Qualities in Autism, and (3) Food and Dietary Intervention and Therapy in Autism. This organization provides the reader a better basic understanding of pharmacological constituents, including their potential benefits against ASD. Why this book is timely? Firstly, a greater proportion of the population in most developing and developed countries have become open-minded for the use of food ingredients and traditional medicines in spite of the use of allopathic medicines for treatment of diseases. Secondly, there is a huge increase in the prevalence of ASD globally, and until now, there are no proper medications to deal with symptoms or effectively manage comorbidities, behavior, performance, and food intolerances. Thirdly, misunderstanding and confusion exist among the parents of an ASD v vi Foreword by Brian J. Wilkinson individual and their caregivers, and this book provides up-to-date clarification to the public. Another notable factor in this book is that several chapters provide a better understanding of the mechanisms of the effects of various phytochemical constituents, such as sulforaphane, curcumin polyphenols (resveratrol), and flavonoids (luteolin). For instance, there is now an extensive literature on omega-3 fatty acids from nuts, showing they function as precursors for anti-inflammatory agents such as neuroprotectin D1 and resolvins, which might exert significant benefits on many neurological disorders including ASD. In conclusion, I appreciate the efforts of the editors to publish this book, which is a great resource of composite information on food and autism. It should also be a good resource for parents with ASD children, dieticians, nutritionists, nutrition researchers, and other readers with interests in human health. Brian J. Wilkinson School of Biological Sciences Illinois State University Normal, IL, USA Foreword by Magid Abou-Gharbia I was delighted when I received a request from Dr. M. Walid Qoronfleh to write a brief foreword for his book. I have known Dr. Qoronfleh for many years, and I have been impressed by his accomplishments in the biomedical field. During the last decade, Dr. Qoronfleh and I were among the team of Arab Expatiate Scientists (AES) who worked with Qatar Foundation to help in promoting Qatar research culture. In the process, we embarked on several new research initiatives in several important research areas. In the biomedical area, we also worked together on put- ting together and writing the planning document that was used to establish Qatar Biomedical Research Institute (QBRI), where significant biomedical research is currently being conducted today. As a drug discovery researcher for over three decades in the pharmaceutical industry and academia, my research teams have always explored innovative approaches for design and synthesis of novel therapeutics for treatment of many diseases including central nervous system (CNS) disorders. We successfully discov- ered ten marketed drugs. Examples of CNS disorder drugs include the antidepres- sants Effexor® and Pristiq®, the sedative Sonata®, and the analgesic Dezocine®. While pursuing our drug discovery research, we were conscious of the importance of natural products therapeutic potential as well as the role of nutrition in preventing and ameliorating disease symptoms. Our efforts led to the discovery of natural products drugs like Mylotarg® and Toresil®. I am pleased to provide a foreword to Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management. Having such book is a good step in the direction toward increasing public awareness of the benefit of nutrition in preventing neurological diseases such as autism. I believe this book will serve as a good introduction to the benefit of personalized food in disease prevention and disease therapy. Magid Abou-Gharbia Moulder Center for Drug Discovery Research School of Pharmacy, Temple University Philadelphia, PA, USA vii Foreword by Theodore DeFrank Having known Dr. Qoronfleh for many years, it is an honor to submit a foreword for the book Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management. I worked with Dr. Qoronfleh during our years together at Pierce Biotechnology, where he was the Director of R&D, developing new technologies and reagents for proteomics research. He was instrumental in positioning Pierce to be a leader in this emerging field in the advent of creating personalized medicine as an approach to therapeutic treatment. After I moved to Active Motif, a life science research company specializing in epigenetics, we continued our dialog on how environmental factors affect gene expression and hence one’s health. The book edited by Drs. Mohamed Essa and M. Walid Qoronfleh further advances this topic to the field of autism spectrum disorders. Theodore DeFrank Active Motif Inc. Carlsbad, CA, USA ix Preface Synopsis of the Book Nature has bestowed on mankind an overabundance of edible vegetables, fruits, nuts, and seeds. The availability of a variety of nutrients and bioactive compounds in these natural products play a crucial role in the health and disease status of human beings. Hippocrates said “Let food be thy medicine and medicine be thy food.” Awareness and specific interest in natural medicine have substantially increased and continue to rise. The practice has taken hold in our society, and this wide acceptance emphasizes an integrative health approach that addresses body, mind, and spirit. Food and its active phytochemicals are used in prevention, cure, and/or management of various neurological disorders, neurodevelopmental

Load more