Annual Report 2012 amfAR,The Foundation for AIDS Research Contents

amfAR in 2012: Program Highlights 04

Grants, Fellowships, and Awards 07

Research Grants

TREAT Asia Awards

GMT Initiative Awards

Public Policy Awards

Message from the Treasurer and the Chair of the Finance and Budget Committee 13

Financial Highlights 14

Leadership and Advisory Committees 16

Board of Trustees

Scientific Advisory Committee

Program Advisory Council

Management Group

amfAR, The Foundation for AIDS Research, is dedicated to ending the global AIDS epidemic through innovative research.

2 From the Chairman and the CEO Dear Friends and Supporters,

An amfAR grant awarded at the tail end of scal year 2012 contributed to one of the biggest HIV research breakthroughs of recent years. The grant, made under the auspices of our amfAR Research Consortium on HIV Eradication (ARCHE), enabled a team of scientists to establish a research collaboratory to explore and document possible pediatric HIV cure cases. It was through their coordinated efforts that the historic rst case of a child being cured of HIV was veri ed and subsequently reported in March 2013.

The case appears to hinge on the fact that this “Mississippi child” was treated with a cocktail of antiretroviral drugs soon after birth. While the child continues to be monitored and the case has yet to be replicated, it adds to a growing body of knowledge about a potential HIV cure, much of it being generated by scientists working collaboratively under amfAR’s three-year old ARCHE program.

This exciting development capped a productive year in which we awarded 34 new research grants and fellowships, and amfAR-funded investigators published more than 40 research papers in leading scienti c journals.

Research continues to drive our international programs, too, as we strive to resolve unanswered questions, ll gaps in data, and determine which interventions are most effective for particular populations. Through our policy program, we continue to work with elected of cials to ensure that AIDS-related public policies are informed by the science and that critical programs are adequately resourced.

As always, none of this important work would be possible without your generous support, and we thank you for playing your part in our collective progress toward an AIDS-free future.

Kenneth Cole Kevin Robert Frost Chairman of the Board Chief Executive Of cer

3 amfAR in 2012: Program Highlights

Research • amfAR played a prominent role in research-focused programming at the 2012 International AIDS Conference. Vice • In June 2012, a think tank organized President and Director of Research Dr. Rowena Johnston by amfAR in brought participated in a two-day pre-conference cure symposium— together 12 scientists involved in titled “Towards and HIV Cure”—co-chaired by Nobel prize- various aspects of HIV cure research, winning scientist Dr. Françoise Barré-Sinoussi and Dr. Steven along with two bioethicists, to explore Deeks. Dr. Johnston also co-chaired a conference session the potential for an HIV cure in infants titled “Gender and Science: Shifting the Paradigm in HIV and children. As a result, amfAR Research.” awarded a grant to Drs. Deborah • Research studies make the greatest impact on the AIDS Persaud of Johns Hopkins Children’s eld and on the broader scienti c community when they are Center and Katherine Luzuriaga of published in scienti c journals. In 2012, more than 40 scienti c the University of Massachusetts publications resulted from amfAR-funded research. to establish a pediatric research collaboratory to investigate possible cases of an HIV cure in children. TREAT Asia Shortly thereafter, the researchers were able to document the historic rst case • TREAT Asia (Therapeutics Research, Education, and AIDS of a child being cured of HIV (reported Training in Asia) is a network of clinics, hospitals, and research in March 2013). institutions working with civil society to ensure the safe and amfAR grantees Dr. effective delivery of HIV/AIDS treatments throughout Asia • amfAR awarded more than $5 million Deborah Persaud and the Paci c. Facilitated by amfAR, TREAT Asia seeks to of Johns Hopkins in grants and fellowships to support strengthen HIV/AIDS care, treatment, and management skills 34 research projects in 2012. Many of Children’s Center (top) and Dr. among health care professionals through education and these awards were for cure-focused Katherine Luzuriaga training programs developed by experts in the region. studies aimed at answering critical of the University questions such as how, where, and of Massachusetts • In December 2011, ViiV Healthcare continued its productive why does HIV persist in infected played a central role in partnership with TREAT Asia by awarding a new grant to people—even while they are on documenting the rst address the healthcare challenges HIV-positive children face case of a child being as they age into adolescence. Research supported by this antiretroviral therapy (ART). Five of the cured of HIV. recipients were junior investigators who funding is focusing on integrating reproductive healthcare, received Mathilde Krim Fellowships in treatment adherence among teenagers, and studying the risk Basic Biomedical Research. of bone damage due to lifelong ART. • amfAR continues to advance cure research through its amfAR • With support from Merck, TREAT Asia organized educational Research Consortium on HIV Eradication (ARCHE). In 2012, activities in advance of a “test and treat” pilot study with more than $1.5 million in funding went to seven collaborative men who have sex with men (MSM) and transgender women teams of researchers working in areas considered central (TG) conducted by the Thai Red Cross AIDS Research to HIV eradication: pinpointing the location of all the viral Centre in three provinces in . As part of a community reservoirs where HIV hides in the body; determining how these preparedness and consultation component leading up to the reservoirs are formed and why they persist despite antiretroviral project, TREAT Asia held a forum in Bangkok in May 2012 therapy; finding more accurate ways of measuring the size of the reservoirs; and nding a way to eliminate the reservoirs altogether. • ARCHE grantees continue to build on previous progress made with amfAR funding. Dr. Sarah Palmer is researching virus clones, seeking to understand how they arise and what they mean for efforts to rid the body of HIV. Dr. Robert Siliciano’s prior ARCHE research identi ed a drug that reactivates dormant virus so that it can be treated with antiretroviral therapy. Continuing with this line of study, Dr. Siliciano is determined to understand the mechanism behind HIV’s ability to remain latent and the important rami cations it has for the design of future cure strategies. And Dr. David Margolis aims to develop an ultra-sensitive method of detecting virus, which could be used in a laboratory as well as clinical setting. Nurses and counselors from Lampang Hospital, Thailand, attended a “test and treat” workshop organized by TREAT Asia in June, 2012.

4 4 to gauge MSM/TG • At the International AIDS Conference, amfAR released community leaders’ an “Action Agenda to End AIDS,” developed with AVAC interest in “test and to identify ve major short-term priorities for global AIDS treat” and discuss programs together with realistic, annual targets that must the potential bene ts be achieved through 2015. The report was the focus of and limitations of the a satellite session at the conference titled “Getting Real strategy. About Getting to the End of AIDS.” A panel discussion moderated by renowned journalist Charlayne Hunter-Gault • In 2012, TREAT included Anthony Fauci, M.D., director of the National Asia was awarded Institute for Allergy and Infectious Diseases; Mike Cohen, a new grant from M.D., professor of epidemiology at the University of North the U.S. National An HIV-positive child getting a check-up from Carolina; Helen Rees, M.D., executive director of the Wits Institutes of Health a physician in a Cambodian clinic. Reproductive Health and HIV Institute in ; (NIH) to study human Mitchell Warren, executive director of AVAC; Chris Collins, papillomavirus, the cause of cervical and anal cancer, in amfAR vice president and director of public policy; and perinatally HIV-infected female and male adolescents in other leading AIDS experts. Thailand and Vietnam. The grant builds on earlier research conducted with the Thai Red Cross AIDS Research Centre. • amfAR also produced a range of informative reports and This innovative study reects TREAT Asia’s growing issue briefs in FY2012, covering topics such as The Effect commitment to better understanding the long-term impact of of Budget Sequestration on Global Health, Ending the HIV on adolescents growing up with the infection. HIV Epidemic Among Gay Men in the , and Estimating the Human Impact of Global Health Funding in • In 2011, the NIH renewed a major research grant to support the President’s Fiscal Year 2013 Budget Proposal. TREAT Asia’s work in the Asia-Paci c region for a second ve- year period. As the regional representative of the International Epidemiology Databases to Evaluate AIDS (IeDEA) since 2006, TREAT Asia has been contributing data from its adult and pediatric observational cohorts to a global database that allows researchers to address key questions about ART outcomes and how best to optimize treatment approaches.

Public Policy • Through its public policy office in Washington, D.C., amfAR educates policy makers, the media, and the public about evidence-based policies to address HIV/AIDS in the U.S. and around the world. In 2012, amfAR continued to promote rational AIDS-related policies based on the most current scienti c knowledge. Chris Collins, amfAR’s vice president and director of public policy (far left) • In June 2012, amfAR held a Capitol Hill briefing in Washington, participated in a panel during the 2012 International AIDS Conference in Washington, D.C. D.C., bringing together researchers at the cutting edge of scienti c discovery to discuss a range of novel approaches being explored in the search for a cure for HIV/AIDS. The GMT Initiative (formerly MSM Initiative) highly informative panel discussion covered topics such as stem cells, gene therapy, medications, and immune response • Since 2007, amfAR has been serving the HIV-related needs modi cations such as therapeutic vaccines. The event also of gay men, other men who have sex with men (MSM), featured an engrossing conversation between renowned and transgender individuals (collectively, GMT) throughout broadcast journalist Judy Woodruff and Timothy Brown, the the developing world through its MSM Initiative. The “Berlin Patient,” the rst and only person known to be cured of program was recently renamed The GMT Initiative to better HIV. reect the diversity of the people it serves. Through small, targeted grants to grassroots groups, amfAR helps expand • Other Capitol Hill briefings in 2012 focused on combination access to HIV education and prevention services; supports prevention approaches and the research agenda needed to advocacy aimed at increasing funding for prevention end the HIV epidemic, with participants including U.S. Global and treatment services; and works to end the stigma, AIDS Coordinator Dr. Eric Goosby and Dr. Chris Beyrer of the discrimination, and violence that threaten the lives of GMT Johns Hopkins Center for Public Health and Human Rights. and fuel the spread of HIV/AIDS.

5 • In 2012, amfAR made community awards totaling more than • Led by Director Kent Klindera, the GMT Initiative was well- $650,000 to 39 organizations throughout its five target regions: represented in several sessions at the 2012 International AIDS Africa, Asia-Paci c, the Caribbean, Eastern Europe and Conference, with community partners presenting data from Central Asia, and Latin America. The awards support the work amfAR-supported projects. Highlights included a presentation on of grassroots groups working to reduce the spread and impact sustainable funding during a Global Forum on MSM and HIV pre- of HIV among GMT in hard hit regions of the developing world. conference meeting, and a skills-building session on community engagement in GMT-related research.

Public Information • amfAR continued to work closely with the media in 2012 to raise the pro le of HIV/AIDS, both domestically and internationally, and to help ensure the accuracy of AIDS press coverage. Articles and reports involving amfAR were carried in numerous media outlets, including , , The Washington Post, the , Reuters, , and The Members of the Kenyan community-based organization and amfAR Huffington Post. grantee, HOYMAS, light candles in remembrance of those who have • Major news outlets died of HIV/AIDS. including The Wall Street Journal, • The GMT Initiative also made five awards as part of its the Associated Advocacy in Action program, which supports GMT-led Press, Bloomberg community-based organizations that wish to influence policies News, and Reuters of governments and external donors, and six awards for sought commentary its Evidence in Action program, which funds and evaluates from amfAR’s community-led programs for scale-up, utilizing the science of leadership during the combination strategies. The awards for these two programs in International AIDS 2012 totaled more than $180,000. Conference in July • With the Johns Hopkins Bloomberg School of Public Health, 2012. amfAR published Achieving an AIDS-Free Generation for • amfAR has long Gay Men and Other MSM, a new report providing the most bene ted from the comprehensive analysis to date of HIV-related funding and voices and the visibility programming for this population. of a wide range of amfAR Chairman and prominent public Global Fundraising Chairman Sharon • In November 2011, amfAR published a Fundraising Toolkit Stone help keep the ght against AIDS for GMT-led advocacy in low- and middle-income countries, gures. In 2012, in the public eye. offering general tips on fundraising and information about these supporters who is funding GMT groups. The toolkit is available in English, included amfAR’s Russian, and Spanish. Global Fundraising Chairman , amfAR ambassadors Cheyenne Jackson, Janet Jackson, Milla Jovovich, Liza Minnelli, and Michelle Yeoh, as well as Sarah Jessica Parker, Heidi Klum, Alan Cumming, John Benjamin Hickey, Janelle Monáe, Jennifer Hudson, Elizabeth Hurley, Debbie Harry, Diane Kruger, Kylie Minogue, fun., Jessie J, Theophilus London, Chris Tucker, Adrien Brody, Dita Von Teese, Stanley Tucci, Chelsea Handler, and Katy Perry, among many others. • amfAR publishes a wide range of educational materials, program reports, and periodicals in an effort to communicate the Foundation’s message and the need for AIDS research. Periodicals produced in both print and electronic formats in 2012 included: Innovations, amfAR’s newsletter; the TREAT Asia Report, Members of SOMOSGAY, a GMT Initiative grantee, meet at their distributed widely to an international audience; and a monthly community center to discuss HIV prevention for Paraguay’s LGBT email newsletter distributed to more than 54,000 subscribers. population.

6 2012 RESEARCH Quantifying HIV persistence under early HAART RESEARCH FELLOWSHIPS in children FELLOWSHIPS, GRANTS, Principal Investigator: Deborah Persaud, M.D. Pursuing HIV Eradication AND AWARDS Johns Hopkins University Baltimore, MD Impact of TLR ligands mediated IL-10 production Co-Investigator: Katherine Luzuriaga, M.D. on HIV persistence All projects listed below were awarded University of Massachusetts Medical School Franck Dupuy, Ph.D. amfAR funding during the period October 1, Worcester, MA Vaccine and Gene Therapy Institute of Florida $383,155 Port St. Lucie, FL 2011, through September 30, 2012. $125,000 Identi cation of drugs that promote the death of amfAR RESEARCH CONSORTIUM ON HIV latently infected cells An atlas of HIV-1 reservoirs, compartments and drug resistant sanctuaries ERADICATION (ARCHE) Principal Investigator: Robert Siliciano, M.D., Ph.D. John Hopkins University Richard Fox, Ph.D. University of Washington HIV persistence after successful CCR5-depleted Baltimore, MD Seattle, WA stem cell transplantation $120,000 $125,000 Principal Investigator: Steven Deeks, M.D. Reactivation of latent HIV-1 through a novel University of California, San Francisco pathway Ex vivo modeling of viral reactivation in virally San Francisco, CA Principal Investigator: Robert Siliciano, M.D., Ph.D. suppressed subjects $47,410 Johns Hopkins University Rémi Fromentin, PharmD., Ph.D. Vaccine and Gene Therapy Institute of Florida Short-term disul ram administration to reverse Baltimore, MD Port St. Lucie, FL latent HIV infection $120,000 $125,000 Principal Investigator: Julian Elliott, Ph.D. Analysis of non-induced provirus as a barrier to Monash University HIV eradication Purging HIV proviral transcription by targeting Clayton, Principal Investigator: Robert Siliciano, M.D., Ph.D. activation of P-TEFb Co-Investigator: Steven Deeks, M.D. Johns Hopkins University Uri Mbonye, Ph.D. University of California, San Francisco Baltimore, MD Case Western Reserve University $312,070 $120,000 Cleveland, OH $125,000 HIV-1 reservoir reduction following allogeneic stem cell transplantation Brain HIV reservoirs: their role in cognitive Principal Investigator: Timothy Henrich, M.D. MATHILDE KRIM FELLOWS IN BASIC impairment in the ART era The Brigham and Women’s Hospital, Inc. BIOMEDICAL RESEARCH Katherine Thompson, Ph.D. Boston, MA Monash University $105,160 Preventing HIV Transmission Clayton, Australia $124,995 Detection and measurement of the HIV reservoir Regulation of epitope-speci c antibodies against Principal Investigator: HIV-1 Env Joseph M. McCune, M.D., Ph.D. Mattias Forsell, Ph.D. University of California, San Francisco Karolinska Institutet RESEARCH GRANTS San Francisco, CA Stockholm, Sweden $119,926 $125,000 Pursuing HIV Eradication Monitoring the levels of total and integrated HIV Discovery of antisense-encoded proteins as novel Ongoing replication in anatomical niches in DNA after ART AIDS vaccine targets the face of ART Principal Investigator: Una O’Doherty, M.D., Ph.D. Nicholas Maness, Ph.D. David Baltimore, Ph.D. University of Pennsylvania Tulane University California Institute of Technology Philadelphia, PA New Orleans, LA Pasadena, CA $96,000 $80,000 (Phase II) $249,600 Identifying the T-cell clonotypes producing The role of dendritic cells in HIV-1 latency persistent virus Optimizing Treatment Paul Cameron, Ph.D. Principal Investigator: Sarah Palmer, Ph.D. SAMHD1-mediated restriction of HIV-1 infection Monash University Swedish Institute for Infectious Disease Control of myeloid cells Melbourne, Australia and Karolinska Institutet Katarzyna Hrecka, Ph.D. $120,000 Solna, Sweden Case Western Reserve University Co-Investigator: Reactivation of HIV transcription via PKC Cleveland, OH agonists and HDACs Daniel Douek, M.D., M.R.C.P., Ph.D. $124,962 Vaccine Research Center, NIAID, NIH Koh Fujinaga, Ph.D. Bethesda, MD Identi cation of novel RNA-protein interactions in University of California, San Francisco Co-Investigator: Frederick Hecht, M.D. HIV-1 particle genesis San Francisco, CA University of California, San Francisco Sebla Bulent Kutluay, Ph.D. $120,000 San Francisco, CA Aaron Diamond AIDS Research Center Administration of an ACE-inhibitor to decrease $164,743 New York, NY the latent reservoir $125,000 Identifying HIV-infected T cell clonotypes Hiroyu Hatano, M.D. by single-cell sequencing Lentiviral resistance to Tetherin/BST-2 University of California, San Francisco Principal Investigator: Sarah Palmer, Ph.D. Ruth Serra-Moreno, Ph.D. San Francisco, CA Swedish Institute for Infectious Disease Control New England Primate Research Center $120,000 and Karolinska Institutet Harvard Medical School Identi cation of cellular factors required to Solna, Sweden Southborough, MA maintain HIV latency Co-Investigator: $125,000 Jonathan Karn, Ph.D. Daniel Douek, M.D., M.R.C.P., Ph.D. Case Western Reserve University Vaccine Research Center, NIAID, NIH Cleveland, OH Bethesda, MD $250,000 CoInvestigator: Frederick Hecht, M.D. University of California, San Francisco San Francisco, CA $239,599

7 T memory stem cells: a new cellular reservoir 2012 TREAT ASIA GRANTS Oon Tek Ng, M.B.B.S., M.R.C.P. for HIV-1 Tan Tock Seng Hospital Mathias Lichterfeld, M.D. AND AWARDS , Singapore Massachusetts General Hospital $16,000* Boston, MA $250,000 Shinichi Oka, M.D., Ph.D. *Supported with funds from the National Institute National Center for Global Health and Medicine Eliminating the latent reservoir through self- of Allergy and Infectious Diseases of the National Shinjuku, speci c antibodies Institutes of Health under award number $16,000* Douglas Nixon, M.D. U01AI069907. University of California, San Francisco Praphan Phanuphak, M.D., Ph.D. San Francisco, CA HIV-NAT / Thai Red Cross AIDS Research Center $120,000 ADULT RESEARCH Bangkok, Thailand $20,000* Biomarkers of virologic control in early-treated TREAT ASIA HIV OBSERVATIONAL DATABASE Sanjay Pujari, M.D. HIV-seronegative children (TAHOD) Deborah Persaud, M.D. Institute of Infectious Diseases Pune, Johns Hopkins University Romanee Chaiwarith, M.D., M.H.S. $20,000* Baltimore, MD Chiang Mai University $120,000 Chiang Mai, Thailand Winai Ratanasuwan, M.D. $20,000* Characterization and inhibition of the macrophage Siriraj Hospital, Mahidol University Bangkok, Thailand reservoir of HIV-1 Yi-Ming Chen, M.D., Sc.D. $7,850 Quentin Sattentau, Ph.D. National Yang-Ming University University of Oxford Taipei, Pham Thi Thanh Thuy, M.D. Oxford, $20,000* Bach Mai Hospital $120,000 Hanoi, Vietnam Jun Yong Choi, M.D., Ph.D. $20,000* CD4+ T cell subsets: targets for HIV infection Yonsei University College of Medicine and latency Seoul, Saphonn Vonthanak, M.D., Ph.D. John Tilton, M.D. $16,500* National Center for HIV/AIDS, Dermatology & Case Western Reserve University STDS / Cambodia National Institute of Public Rossana Ditangco, M.D. Cleveland, OH Health Asian Foundation for Tropical Medicine, Inc. as $120,000 Phnom Penh, Cambodia intermediary for the Research Institute of Tropical $20,000* Size of the HIV reservoir and ongoing replication Medicine (RITM) in de ned patient cohorts Muntinlupa City, Evy Yunihastuti, M.D., Ph.D. Linos Vandekerckhove, M.D., Ph.D. $20,000* Cipto Mangunkusumo General Hospital Ghent University Hospital Jakarta, Indonesia Adeeba Kamarulzaman, M.B.B.S., F.R.A.C.P. Ghent, Belgium $20,000* $249,600 University of Malaya Kuala Lumpur, Malaysia Fujie Zhang, M.D. Sulfonation-dependent reactivation in primary $20,000* Beijing Ditan Hospital, Capital Medical University T cell models of HIV latency Beijing, China Pacharee Kantipong, M.D. John Young, Ph.D. $16,000* The Salk Institute for Biological Studies Chiangrai Prachanukroh Hospital La Jolla, CA Chiang Rai, Thailand $120,000 $15,500 TAHOD STUDY ON THE SOCIO-ECONOMIC Sasisopin Kiertiburanakul, M.D., M.H.S. DETERMINANTS OF TUBERCULOSIS IN ASIA Ramathibodi Hospital, Mahidol University RESEARCH AWARDS Bangkok, Thailand Rossana Ditangco, M.D. $20,000* Asian Foundation for Tropical Medicine, Inc. as Optimizing Treatment intermediary for the Research Institute of Tropical Nguyen Van Kinh, M.D., Ph.D. Medicine (RITM) National Hospital of Tropical Diseases Assessing the impact of HIV/AIDS service delivery Muntinlupa City, Philippines Hanoi, Vietnam in Malawi: Zomba District ART observational $15,114* cohort study $20,000* Sumeet Sodhi, M.D., M.P.H. Adeeba Kamarulzaman, M.B.B.S., F.R.A.C.P. Nagalingeswaran Kumarasamy, M.D., M.B.B.S., Dignitas International University of Malaya Ph.D. Toronto, Kuala Lumpur, Malaysia YRG Centre for AIDS Research and Education, $125,000 $10,164* VHS Chennai, India Sasisopin Kiertiburanakul, M.D., M.H.S. $20,000* Ramathibodi Hospital, Mahidol University Bangkok, Thailand Christopher Lee, M.B.B.S., M.R.C.P. $8,702* Sungai Buloh Hospital Sungai Buloh, Malaysia Patrick Li, M.B.B.S. $15,000* Queen Elizabeth Hospital , China Patrick Li, M.B.B.S. $3,000* Queen Elizabeth Hospital Hong Kong, China Tuti Parwati Merati, M.D., Ph.D. $20,000* Udayana University Denpasar, Indonesia Tuti Parwati Merati, M.D., Ph.D. $24,274* Udayana University School of Medicine Denpasar, Indonesia Oon Tek Ng, M.B.B.S., M.R.C.P. $20,000* Tan Tock Seng Hospital Singapore, Singapore $8,250*

8 Praphan Phanuphak, M.D., Ph.D. Tim Read Incorporating high resolution anoscopy in AIN HIV-NAT / Thai Red Cross AIDS Research Center Melbourne Sexual Health Centre screening and treatment programs for MSM in Bangkok, Thailand Carlton, Australia Indonesia, Malaysia, and Thailand $8,244* $6,525* Nittaya Phanuphak, M.D. HIV-NAT / Thai Red Cross AIDS Research Center Pham Thi Thanh Thuy, M.D. Norman Roth, M.B.B.S., FA.Ch.S.H.M. Bangkok, Thailand Bach Mai Hospital Prahran Market Clinic Pty Ltd. $175,000 Hanoi, Vietnam South Yarra, Australia $13,740* $6,450* Study on anal human papillomavirus infection and anal intraepithelial neoplasia among MSM in Nguyen Van Kinh, M.D., Ph.D. Darren Russell, M.D. Indonesia, Malaysia, and Thailand National Hospital of Tropical Diseases Cairns Sexual Health Service Nittaya Phanuphak, M.D., Ph.D. Hanoi, Vietnam Cairns, Australia HIV-NAT / Thai Red Cross AIDS Research Center $18,320* $6,225* Bangkok, Thailand Fujie Zhang, M.D. Nathan Ryder, M.D. $200,000 Beijing Ditan Hospital, Capital Medical University Northern Territory Dept of Health & Community Asia Paci c HIV Research Collaboration: Beijing, China Services, Sexual Health & Blood Borne Virus Cancer Studies $8,244* Program Matthew G. Law, Ph.D. Darwin, Australia University of New South Wales $1,350 Sydney, Australia ASIA PACIFIC HIV RESEARCH David Smith $38,202* COLLABORATION: TAHOD, TB, HCV Sexual Health and AIDS Services (SHAIDS) Asia Paci c HIV Research Collaboration: Lismore, Australia Data Harmonization Matthew G. Law, Ph.D. $6,900* University of New South Wales Matthew G. Law, Ph.D. Sydney, Australia David Sowden, M.B.B.S University of New South Wales $182,029* Nambour General Hospital Sydney, Australia Nambour, Australia $36,719* $7,500* A Cambodian clinical research network for HIV AUSTRALIA HIV OBSERVATIONAL DATABASE Sharon Taylor, C.N.C. and TB (AHOD) Hunter New England Health, Clinic 468, Sok Thim, M.D. and Anne Goldfeld, M.D. Tamworth Sexual Health Service Global Health Committee, Inc. Debbie Allen, M.B.Ch.B., Dip. Tamworth, Australia Boston, MA Central Coast Local Health District $975 $297,750* Holden Street Clinic Gosford, Australia David Templeton, Ph.D. A randomized open-label study of $1,800 RPA Sexual Health Clinic second-line ART Camperdown, Australia David Cooper, M.D. Katherine Brown, M.D. $600 University of New South Wales Illawarra Shoalhaven Local Health District Sydney, Australia Wollongong, Australia Rick Varma, MRCP $100,000 $1,800 Nepean Sexual Health Clinic Kingswood, Australia Teman-Teman, Indonesia Andrew Carr, M.D. $900 Jintanat Ananworanich, M.D., Ph.D. St. Vincent’s Hospital Thai Red Cross AIDS Research Center, SEARCH Darlinghurst, Australia Ian Woolley, M.B.B.S., F.R.A.C.P. Bangkok, Thailand $7,350* Southern Health $2,991 Monash Medical Centre - Clayton William Donohue, M.B.B.S. Melbourne, Australia O’Brien Street Practice $4,725 Adelaide, Australia PEDIATRIC RESEARCH $2,025 Lynne Wray, M.B.B.S. Sydney Sexual Health Centre, Sydney Hospital TREAT ASIA PEDIATRIC HIV OBSERVATIONAL Jennifer Hoy, M.B.B.S. Sydney, Australia DATABASE (TApHOD) Victorian HIV Service, Infectious Diseases $5,175* Department, The Alfred Hospital Jintanat Ananworanich, M.D. Melbourne, Australia HIV-NAT / Thai Red Cross AIDS Research Center $6,300* Bangkok, Thailand (Individual projects) $18,680 Eva Jackson, M.B.B.S. Blue Mountains Sexual Health and HIV Clinic Asia Paci c HIV Research Collaboration: Kulkanya Chokephaibulkit, M.D. Katoomba, Australia AHOD, Suicide Study Siriraj Hospital, Mahidol University $1,350 Matthew G. Law, Ph.D. Bangkok, Thailand University of New South Wales $23,435 Mark Kelly, M.B.B.S. Sydney, Australia Prince Charles Hospital, Brisbane Sexual Health $212,770* Rawiwan Hansudewechakul, M.D. and HIV Service ChiangraiTrương H ữPrachanukrohu Khanh, M.D. Hospital Brisbane, Australia Identifying Biomarkers of Anal Intraepithelial Chiangrai, Thailand $7,125* Neoplasia in Thai MSM $25,780 Nittaya Phanuphak, M.D. David Nolan HIV-NAT / Thai Red Cross AIDS Research Center Royal Perth Hospital Bangkok, Thailand Children’s Hospital 1 Perth, Australia $100,000* Ho Chi Minh City, Vietnam $5,550* $29,280 Nagalingeswaran Kumarasamy, M.D., M.B.B.S. YRG Centre for AIDS Research and Education, VHS Chennai, India $18,575

9 Trương Hữu Khanh, M.D.

Nia Kurniati, M.D. Trương Hữu Khanh, M.D. Treatment response of chronic viral hepatitis B to Cipto Mangunkusumo General Hospital Children’s Hospital 1 tenofovir and lamivudine-containing antiretroviral Jakarta, Indonesia Ho Chi Minh City, Vietnam regimens in HIV-infected adolescents $15,325 $24,500 Linda Aurpibul, M.D. Chiang Mai University Nguyen Van Lam, M.D. Pope Kosalaraksa, M.D. Chiang Mai, Thailand National Hospital of Pediatrics Khon Kaen University $9,433* / $8,603 Hanoi, Vietnam Khon Kaen, Thailand $27,530 $18,500 Social Support for Children and Adolescents with HIV Pagakrong Lumbiganon, M.D. Nia Kurniati, M.D. Fong Siew Moy, M.D. Khon Kaen University Cipto Mangunkusumo General Hospital Hospital Likas Khon Kaen, Thailand Jakarta, Indonesia Kota Kinabalu, Malaysia $20,597 $18,500 $10,000 Fong Siew Moy, M.D. Nguyen Van Lam, M.D., MSC Interventions to Promote Retention in Formal Hospital Likas National Hospital of Pediatrics School System Kota Kinabalu, Malaysia Hanoi, Vietnam Jintanat Ananworanich, M.D. $2,695 $12,860 (year 1) / $23,500 (year 2) HIV-NAT / Thai Red Cross AIDS Research Center Revathy Nallusamy, M.B.B.S. Virat Sirisanthana, M.D. Bangkok, Thailand Penang Hospital Chiang Mai University-Research Institute for $10,922 Georgetown, Malaysia Health Sciences Providing knowledge about HIV and sex $3,535 Chiang Mai, Thailand education for HIV positive and disclosed $16,500 Kamarul Razali, M.D. adolescents and their caregivers in Pediatric Institute, Hospital Kuala Lumpur Do Chau Viet, M.D. Ho Chi Minh City Kuala Lumpur, Malaysia Children’s Hospital 2 Le Ngoc Oanh, M.D. $9,450 Ho Chi Minh City, Vietnam Worldwide Orphans Foundation $23,500 Maplewood, NJ Virat Sirisanthana, M.D. $2,000 Chiang Mai University-Research Institute for Health Sciences Plan for supportive discussion groups for Chiang Mai, Thailand (Individual projects) adolescents from below 10 to 15 years of age $21,570 Do Chau Viet, M.D. Optimizing HIV Treatment for Children In Asia: Children’s Hospital 2 Do Chau Viet, M.D. Developing Strategies for Lifelong Care Ho Chi Minh City, Vietnam Children’s Hospital 2 Praphan Phanuphak, M.D., Ph.D. $2,000 Ho Chi Minh City, Vietnam HIV-NAT / Thai Red Cross AIDS Research Center $19,280 Bangkok, Thailand Monkey Meeting $4,000 (supplement to funding for previous year) John Tucker Saphonn Vonthanak, M.D. $147,273 New Hope for Cambodian Children National Center for HIV/AIDS, Dermatology & Killeen, TX STDS / Cambodia National Institute of Effect of socioeconomic factors on cognition, $2,000 Public Health adaptive function and school status Phnom Penh, Cambodia Jintanat Ananworanich, M.D., P.h.D. Reinforcing on HIV disclosure and follow-up of $32,055 HIV Netherlands Australia Thailand Research HIV infected children and adolescents in National Collaboration (HIV-NAT) Pediatric Hospital Ketut Dewi Kumara Wati, M.D. Bangkok, Thailand Ung Vibol, M.D. Udayana University School of Medicine $50,000 National Pediatric Hospital Denpasar, Indonesia Phnom Penh, Cambodia $5,560 Study of atazavanir/ritonavir-based HAART in Thai $2,000 HIV-infected children Nik Khairulddin Nik Yusoff, M.D. Torsak Bunupuradah, M.D. Psychosocial support for children and Hospital Raja Perempuan Zainab II HIV-NAT / Thai Red Cross AIDS Research Center adolescents living with HIV/AIDS Kota Bharu, Malaysia Bangkok, Thailand Nia Kurniati, M.D. $10,260 $42,342 Cipto Mangunkusumo General Hospital Jakarta, Indonesia Understanding adherence, stigma, and behavioral $2,000 risk factors of adolescents in TApHOD using audio ASIA PACIFIC HIV RESEARCH Our Village COLLABORATION: TAPHOD computer assisted self-interview (ACASI) Wasana Prasitsuebsai, M.D., M.P.H. John Tucker New Hope for Cambodian Children Matthew G. Law, Ph.D. HIV-NAT / Thai Red Cross AIDS Research Center Bangkok, Thailand Killeen, TX University of New South Wales $175,004 Sydney, Australia $12,000* $255,991* Bone Mineral Density Among HIV-Infected Adolescents Kulkanya Chokephaibulkit, M.D. TREAT ASIA STUDIES TO EVALUATE Siriraj Hospital, Mahidol University RESISTANCE – PEDIATRICS (TASER-P) Bangkok, Thailand $10,000* Jintanat Ananworanich, M.D. HIV-NAT / Thai Red Cross AIDS Research Center Cardiovascular abnormalities and carotid intima- Bangkok, Thailand media thickness among HIV-infected adolescents $23,500 in Thailand Kulkanya Chokephaibulkit, M.D. Kulkanya Chokephaibulkit, M.D. Siriraj Hospital, Mahidol University Siriraj Hospital, Mahidol University Bangkok, Thailand Bangkok, Thailand $42,726 $12,500

10 2012 GMT INITIATIVE AWARDS Caribbean Community Based VCT on HIV among MSM Population in Belgrade as an Additional Working Together to Enhance the MSM Measurement for HIV Prevention Community in Antigua and Barbuda Safe Pulse of Youth (SPY) GMT INITIATIVE COMMUNITY AWARDS Antigua Resilience Collective Inc. (ARC) Belgrade, Serbia St. John’s, Antigua and Barbuda $8,000 Africa $10,000 Accessible, Quality and Reliability, on Equal Terms MSM Participation in the response against AIDS Scaling Up the Quality and Quantity of Life of NGO Equal Opportunities in Burundi MSM Living with HIV in Belize Dushanbe, Tajikistan Reseau National Des Jeunes Engages Dans La Collaborative Network of Persons Living with HIV $20,000 Lutte Contre Le VIH/SIDA (C-NET+) Bujumbura, Burundi Belize City, Belize Increasing Access to HIV Prevention, Care and $12,080 $19,697 Support for MSM in Prisons Nikolaev Regional Public Youth Movement Awareness, Capacity Building and Treatment/Care Empowering Male Sex Workers and Transgender Penitentiary Initiative Health Options For Young Men on HIV, AIDS Populations in San Pedro de Macoris Nikolaev, Ukraine and STIs Grupo Este Amor $15,000 Nairobi, Kenya La Romana, Dominican Republic $20,100 $19,908 Medical and Social Support, HIV Prevention among Gay Men and MSM Evidence Based Target HIV Prevention Project Deepening Outreach to Hearing Impaired MSM in Public Youth Organization Self Help Club Life + Centre for the Development of People Jamaica Odessa, Ukraine Lilongwe, Malawi Jamaica AIDS Support for Life (JASL) $20,000 $20,000 Kingston, Jamaica $20,000 Breaking Down the Taboos and Raising Awareness amongst MSM on HIV and AIDS Fight the Hate: Mitigating Risks and Enabling Safe Latin America WhyCantWeGetMarried.Com West Africa Chapter Spaces for LGBT Jamaicans Jamaica Forum for Lesbians, All-Sexuals & Gays Acceso Universal para población Trans que se Freetown, Sierra Leone dedica al trabajo Sexual $10,173 (J-FLAG) Kingston, Jamaica Mesa De Trabajo Nacional See It, Sign It, Share It! Using Arts to Build Deaf $20,000 Cochabamba, Bolivia MSM/TG Leadership on HIV Prevention in $20,000 Leadership Development and Social Support for South Africa Incidencia en los tomadores de decisiones para Gay and Lesbian Memory in Action Tertiary LGBT in Jamaica PRIDE In Action la mejora de los presupuestos y políticas públicas Johannesburg, South Africa de prevención en VIH/SIDA en gays, trans y $15,000 Kingston, Jamaica $12,495 otros HSH en Chile Ahoefa – The House of Peace CES / MUMS Movimiento Por la Diversidad Sexual Espoir Vie–Togo Challenging Self Stigma and Discrimination While Santiago, Chile Lomé, Togo Raising Awareness $20,000 $17,456 United and Strong Inc. Gros Islet, Saint Lucia Análisis de las Trans y los factores en aumento del Icebreakers Uganda MSM Initiative $10,000 VIH y Discriminación Spectrum Uganda Initiatives Asociación Silueta X Kampala, Uganda Homophobia Causes AIDS. Organizing Can End It Guayaquil, Ecuador $12,500 Coalition Advocating for Inclusion of Sexual $19,920 Orientation (CAISO) Port of Spain, Trinidad and Tobago Atención Médica, Psicológica y Prevención del $10,000 VIH-Sida para HSH Asia-Paci c Asociación ALFIL Improving the Service Delivery Model for GLBT, Quito, Ecuador PCA , Empowerment, Advocacy: Improve the MSM/TG & Male Sex Workers in Trinidad & $19,530 Living Status of TG in Chengdu, China Tobago Chengdu Tongle Counseling and Service Center Friends For Life Proyecto Abriendo Caminos Chengdu, China Port-of-Spain, Trinidad and Tobago Asociación Solidaria Para Impulsar El Desarrollo $19,970 $15,000 Humano (ASPI-DH ARCO IRIS) San Salvador, El Salvador Internet-based Advocacy and Empowerment of $20,000 Sexual Health Rights for MSM Youth GZTZ.ORG Eastern Europe and Central Asia Increased participation of trans people in public Guangzhou, China policies on HIV and AIDS $12,000 Access to HIV-Related Services for Transgender Fundacion Llanto, Valor y Esfuerzo (LLAVES) Individuals in the South Caucasus San Pedro Sula, Honduras HIV Intervention in Male Massage Centers Center for Information and Counseling on $19,450 Name withheld by request Reproductive Health–Tanadgoma Sri Lanka Tbilisi, Georgia Sensibilizando a hombres jóvenes indígenas $15,567 $19,970 mayas que tienen sexo con otros hombres Centro de Desarrollo e Investigación sobre Supporting Burmese MSM Migrant Workers in Bringing Safety and Security for the Local GBT Juventud, A.C. Southern Thailand Year 2 Community Campeche, The Human Rights Education Institute of Burma Public Association Kyrgyz Indigo $15,615 (HREIB) Bishkek, Kyrgyzstan Chiang Mai, Thailand $19,663 Atención Integral para Gays y HSH en la Region $19,958 Metropolitana de Panamá Organizational and Educational Work with Third Grupo Génesis Panamá Positivo (GGP+) Age MSM: Our Response to HIV/AIDS Panama, Panama GENDERDOC-M Information Centre $20,000 Chisinau, Republic of Moldova $19,975

11 Centro Fijo y Movil de Consejeria y Testeo Contributing to the increment of men who have Pre-conference programs: AIDS 2012 Voluntario en Asuncion sex with men (MSM) who attend voluntarily to Phill Wilson Asociación Civil SOMOSGAY take HIV testing with pre and post counseling Black AIDS Institute Asuncion, Paraguay Asociación De Hombres Y Mujeres Nuevos De , CA $20,000 Panamá $75,000 Panama, Panama Alma Chalaca: Innovative Workshops by and for $24,000 We Can! We Will! End AIDS! MSM/Transgender PEPs in Lima/Callao, Peru Paul Zeitz, D.O., M.P.H. Asociacion Civil Impacta Salud y Educacion Iguales/Equals/Ñande Joja The End of AIDS, Inc. Lima, Peru SOMOSGAY Wilmington, DE $10,985 Asunción, Paraguay $125,000 $24,000 Concertando Diversidades Para la Prevencion del VIH y Derechos Humanos Para HSH en la Region PULSAR. Power of Evidence San Martin-Peru 2011-2012 The Center for Health and Social Support (SIBALT) GLOBAL ADVOCACY CORPS AWARDS Asociación Diversidad San Martinense Omsk, Russia Tarapoto, Peru $24,000 Strengthening the capacity of CSOs to monitor $20,000 and inuence health, HIV and TB budgets and expenditures in Zimbabwe HSH, población transgénero, VIH y los servicios Nhlanhla Ndlovu de salud en Uruguay GMT INITIATIVE AWARDS Centre for Economic Governance and AIDS in Colectivo Ovejas Negras Africa Montevideo, Uruguay Increasing Access to high-quality, integrated STI/ Cape Town, South Africa $14,500 HIV services for men who have sex with men in $60,555 Bali, Indonesia Yayasan Kasih Suwitno (YKS) Beginning to end AIDS: civil society advocacy to Jakarta, Indonesia scale up high impact prevention and treatment ADVOCACY IN ACTION AWARDS $25,000 interventions in Malawi Rodney Chalera Advocacy in Action Program – China 2012 A health sector intervention to increase the Centre for the Development of People (CEDEP) Beijing Ark of Love PLWHA Supporting Group as competence and sensitivity of health care services Lilongwe, Malawi sponsor for Nanjing Joyful Life Group for gay men and other MSM in Malawi $16,200 Beijing, China Fenway Community Health Center, Inc. $17,000 Boston, MA $25,000 Advocacy in Action – Lao PDR Lao Positive Health Association (LaoPHA) Vientiane, Lao PDR $6,000 Advocacy in Action – Nepal 2012 PUBLIC POLICY GRANTS Blue Diamond Society Kathmandu, Nepal AND AWARDS $14,250

Advocacy in Action Program – Thailand 2012 Northeast Florida AIDS Network Health and Opportunity Network (HON) Donna M. Fuchs T-Nongpue-Banglamoong, Thailand Northeast Florida AIDS Network $6,000 Jacksonville, FL Advocacy In Action – Vietnam: Supplement for $2,000 Project Completion Syringe Exchange in the US, 2011-2012: Institute for Studies of Society, Economy and Assessing Services in a Financially Environment (iSEE) Challenging Environment Hanoi, Vietnam Don C. Des Jarlais, Ph.D. $1,481 Beth Medical Center - Edmond de Rothschild Chemical Dependency Institute New York, NY EVIDENCE IN ACTION AWARDS $90,000 Barriers to Reason: Laws Impacting HIV Access to HIV Services Prevention Efforts among IDUs in the Bandhu Social Welfare Society (BSWS) United States Dhaka, Bangladesh Don C. Des Jarlais, Ph.D. $23,919 Beth Israel Medical Center Screening Project New York, NY Alternatives-Cameroun $90,000 Douala, Cameroon National Minority AIDS Council – 25th Anniversary $24,000 Paul Kawata Promoting Universal Access, behavioural change National Minority AIDS Council and community building for MSM in Grenada Washington, DC GrenCHAP Inc. $25,000 St. George, Grenada A training program for HIV research among MSM $24,000 in developing world settings Ronald D. Stall, Ph.D., M.P.H. University of Pittsburgh Pittsburgh, PA $125,000

12 Message from the Treasurer and the Chair of the Finance and Budget Committee

We are pleased to present the audited nancial statements of amfAR, The Foundation for AIDS Research, for the scal year ending September 30, 2012.

Public support and revenue increased by 4.1 percent over the previous year, to $28.3 million. Due mainly to an increase of $1.2 million in research spending, however, amfAR ended the year with a modest operating deficit of $687,981. amfAR’s operational ef ciency during 2012 is illustrated by a low supporting services ratio—the ratio of fundraising and management expenses to total support and revenue— of 24.7 percent. And of every dollar spent, 75.9 percent was invested directly in critical program activities, demonstrating effective use of donor contributions.

The Foundation’s steady growth in 2012 was accompanied by important programmatic advances. For example, new grants were awarded to collaborative teams of senior scientists pursuing a cure for AIDS through the amfAR Research Consortium on HIV Eradication (ARCHE). In year three of ARCHE, grantees made impressive progress.

In 2012, amfAR again met the stringent requirements of governance and nancial accountability demanded by the Better Business Bureau’s Wise Giving Alliance and was designated a four-star charity—the highest possible rating—by Charity Navigator. The Foundation also met the strict requirements of the federal government’s workplace fundraising program, the Combined Federal Campaign, as well as many state employee workplace giving campaigns.

A copy of the complete audited nancial statements, prepared in accordance with generally accepted accounting principles for not-for-profit organizations as established by the American Institute of Certi ed Public Accountants, is available upon request from amfAR at 120 Wall Street, 13th Floor, New York, NY 10005, and can be accessed by visiting www.amfar.org.

Wallace Sheft, C.P.A. Michael J. Klingensmith Treasurer Chair, Finance and Budget Committee

13 Financial Highlights For the year ended September 30, 2012

Public Support and Revenue Public support $ 6,780,112 Special events 11,606,820 Planned giving 2,862,378 Government funding 5,008,478 Investment income and other revenue 2,021,109 Total public support and revenue $ 28,278,897

Expenses Research $ 8,725,334 TREAT Asia 5,740,985 GMT Initiative 2,046,655 Public Policy 2,317,793 Public Information 3,159,567 Total program services $ 21,990,334

Fundraising 4,754,301 Management and general 2,222,243 Total supporting services $ 6,976,544

Total expenses $ 28,966,878

Change in net assets (687,981) Net assets, beginning of year 31,440,085

Net assets, end of year $ 30,752,104

Statement of Financial Position

Assets Cash and investments $ 29,362,802 Pledges and receivables 8,162,387 Prepaid expenses and other assets 974,399 Furniture, equipment, and leasehold improvements 1,888,607 Total Assets $ 40,388,195

Liabilities Accounts payable and accrued expenses $ 1,732,740 Grants and fellowships payable, net 1,713,122 Deferred support and refundable advances 5,428,345 Other long-term liabilities 761,884 Total liabilities $ 9,636,091

Total net assets 30,752,104

Total liabilities and net assets $ 40,388,195

14 Expenses

Fundraising $ 4,754,301 Management and general 2,222,243 Program 21,990,334

Total $ 28,966,878

Program Expenses

Research $ 8,725,334 TREAT Asia 5,740,985 GMT Initiative 2,046,655 Public Policy 2,317,793 Public Information 3,159,567

Total $ 21,990,334

15 T. Ryan Greenawalt TRUSTEES EMERITI BOARD OF TRUSTEES President/Founder Fiscal Year 2012 Harrison Street Productions Arthur J. Ammann, M.D. New York, NY President, Global Strategies for HIV Prevention Clinical Professor of Pediatrics Chairman of the Board Regan Hofmann University of California, San Francisco Kenneth Cole Global Health Consultant Medical Center Chairman Ringoes, NJ San Rafael, CA Kenneth Cole Productions New York, NY Michael J. Klingensmith Arnold W. Klein, M.D. CEO and Publisher Professor of Medicine/Dermatology Founding Chairman Minneapolis Star Tribune University of California, Los Angeles Mathilde Krim, Ph.D. Minneapolis, MN Beverly Hills, CA Adjunct Professor Mailman School of Public Health Michele V. McNeill, Pharm.D. Columbia University Long Boat Key, FL New York, NY Edward L. Milstein HONORARY TRUSTEES Vice Chairman Co-Chairman Patricia J. Matson Milstein Brothers Capital Partners Mouna E. Ayoub Senior Vice President, Communications (ret.) New York, NY Paris, France ABC, Inc. Cindy D. Rachofsky New York, NY John F. Breglio, Esq. Philanthropist Paul, Weiss, Rifkind, Wharton & Garrison Vice Chairman Dallas, TX New York, NY John C. Simons Vincent A. Roberti Robert L. Burkett Managing Partner Chairman, Roberti+White Corporate Fuel Partners, LLC The Carmen Group Washington, D.C. Washington, D.C. New York, NY CEO Treasurer Palisades Media Corp. Michael Fuchs Wallace Sheft, C.P.A. New York, NY New York, NY Partner (ret.) Bill Roedy Sandra Hernández, M.D. Wurmband, Lerner & Sheft London, UK Chief Executive Of cer Westbury, NY The San Francisco Foundation Raymond F. Schinazi, Ph.D., D.Sc. San Francisco, CA Secretary Frances Winship Walters Professor Mervyn F. Silverman, M.D., M.P.H. Director, Laboratory of Biochemical Pharmacology Sherry Lansing Crockett, CA Emory University Chief Executive Of cer/Founder Decatur, GA The Sherry Lansing Foundation Los Angeles, CA Alan D. Schwartz TRUSTEES Executive Chairman Jane F. Nathanson Guggenheim Partners LLC Psychologist Arlen H. Andelson New York, NY Chair, Jane & Marc Nathanson Andelson Properties Community Foundation Diana L. Taylor Los Angeles, CA Los Angeles, CA Managing Director Wolfensohn & Co. LLC The Rev. Dr. Randolph Nugent President New York, NY General Secretary (ret.) General Board of Global Ministries Belafonte Enterprises, Inc. Kevin Wendle New York, NY United Methodist Church Entrepreneur New York, NY David Bohnett Paris, France Chairman Leonard Rabinowitz President Beverly Hills, CA Studio CL ADJUNCT TRUSTEES Los Angeles, CA Zev Braun President and CEO David E. Bloom, Ph.D. Michael D. Shriver Braun Entertainment Group, Inc. Dept. of Global Health and Population Co-Director, AIDS Policy Research Center Beverly Hills, CA Harvard School of Public Health AIDS Research Institute Boston, MA University of California, San Francisco Jonathan S. Canno San Francisco, CA New York, NY Mario Stevenson, Ph.D. Professor of Medicine Donald A. Capoccia Chief, Division of Infectious Diseases Managing Principal Leonard M. Miller School of Medicine IN MEMORIAM BFC Partners University of Miami Brooklyn, NY Miami, FL Sheldon W. Andelson, Esq. Mrs. Albert D. Lasker R. Martin Chavez, Ph.D. Jonathan M. Mann, M.D., M.P.H. Managing Director Maxine Mesinger Goldman, Sachs & Co. Pauline Phillips New York, NY Natasha Richardson Jane B. Eisner Allan Rosen eld, M.D. Bel Air, CA Peter Scott, Esq. Tom Stoddard Joel D. Weisman, D.O.

16 Founding International Chairman SCIENTIFIC ADVISORY *Dame Bryan Richard Cullen, Ph.D. COMMITTEE Professor *Deceased March 23, 2011 Department of Genetics Duke University Medical Center Mario Stevenson, Ph.D. (Chair) Susanna Cunningham-Rundles, Ph.D. Professor of Immunology SPECIAL APPOINTMENT Professor of Medicine Chief, Division of Infectious Diseases Department of Pediatrics Leonard M. Miller School of Medicine Cornell University Medical College Global Fundraising Chairman University of Miami Sharon Stone Richard Thomas D’Aquila, M.D. Jintanat Ananworanich, M.D. Director, Northwestern HIV Translational Professor Research Center HIV-NAT / Thai Red Cross AIDS Research Center The Howard Taylor Rickets Professor of Medicine, amfAR AMBASSADORS Division of Infectious Diseases, Department of Deborah Anderson, Ph.D. Medicine Northwestern University Cheyenne Jackson Professor and Director Janet Jackson Division of Reproductive Biology Boston University School of Medicine Steven Deeks, M.D. Milla Jovovich Professor in Residence Liza Minnelli Warren A. Andiman, M.D. School of Medicine Michelle Yeou Professor of Pediatrics, Epidemiology University of California, San Francisco and Public Health San Francisco, CA Department of Pediatrics Yale University School of Medicine Sherry Deren, Ph.D. BOARD COMMITTEES Director Michael Betts, Ph.D. Center for Drug Use and HIV Research Executive Committee Assistant Professor College of Nursing Kenneth Cole, Chair Department of Microbiology University of Pennsylvania School of Medicine Roger Detels, M.D., M.S. Michael J. Klingensmith Professor of Epidemiology Mathilde Krim, Ph.D. Jason Brenchley, Ph.D. School of Public Health Patricia J. Matson Investigator University of California, Los Angeles Vincent A. Roberti Vaccine Research Center Wallace Sheft, C.P.A. National Institute of Allergy and Infectious Carl W. Dieffenbach, Ph.D. Mervyn F. Silverman, M.D., M.P.H. Diseases Director John C. Simons National Institutes of Health Division of AIDS (DAIDS) National Institute of Allergy and Infectious Audit Committee Dennis R. Burton, Ph.D. Diseases Wallace Sheft, C.P.A., Chair Professor National Institutes of Health R. Martin Chavez, Ph.D. Department of Immunology John C. Simons The Scripps Research Institute Daniel C. Douek, M.D., Ph.D. Chief, Human Immunology Section Board Development Committee Salvatore T. Butera, D.V.M., Ph.D Vaccine Research Center John C. Simons, Chair Chief Science Of cer National Institute of Allergy and Infectious David Bohnett Scipps CHAVI-ID Diseases Mathilde Krim, Ph.D. The Scripps Research Institute National Institutes of Health Patricia J. Matson Mervyn F. Silverman, M.D., M.P.H. Edward Campbell, Ph.D. D. Peter Drotman, M.D., M.P.H. Assistant Professor Editor in-Chief Compensation and Organizational Development School of Medicine Emerging Infectious Diseases Committee Loyola University at Centers for Disease Control and Prevention John C. Simons, Chair Michael J. Klingensmith Alex Carballo-Dieguez, Ph.D. Anke A. Ehrhardt, Ph.D. Director and Professor Finance & Budget Committee Research Scientist and Associate Professor of Clinical Psychology Department of Psychiatry Michael J. Klingensmith, Chair HIV Center, NYS Psychiatric Institute Columbia University, NY State Psychiatric Institute Vincent A. Roberti Columbia University John C. Simons Jacob D. Estes, Ph.D. Tae-Wook Chun, Ph.D. Head, Tissue Analysis Core Fund Development Committee The AIDS and Cancer Virus Program Vincent A. Roberti, Chair Staff Scientist National Institute of Allergy and Infectious National Cancer Institute-Frederick Jonathan S. Canno Diseases National Institutes of Health Edward L. Milstein National Institutes of Health Homayoon Farzadegan, Ph.D. Investment Committee David B. Clifford, M.D. Professor Michael J. Klingensmith, Chair Department of Epidemiology R. Martin Chavez, Ph.D. Professor Department of Neurology The Johns Hopkins University Edward L. Milstein Washington University School of Medicine Vincent A. Roberti Dianne M. Finkelstein, Ph.D. Wallace Sheft, C.P.A. C. Budd Colby, Ph.D. Director of Biostatistics John C. Simons Principal Cancer Center Biostatistics Colby Biomedical Consultants Massachusetts General Hospital and Harvard Medical School Grant Colfax, M.D. Director of HIV Prevention and Research Diana Finzi, M.P.H., Ph.D. San Francisco Department of Public Health Chief Pathogenesis and Basic Research Branch Deborah Jean Cotton, M.D., M.P.H. National Institute of Allergy and Infectious Professor of Medicine Diseases Department of Medicine National Institutes of Health Boston University School of Medicine

17 Gerald Herbert Friedland, M.D. Michael Lederman, M.D. Jay A. Nelson, Ph.D. Professor and Director, AIDS Program Director, Center for AIDS Research Professor and Director Department of Internal Medicine Professor of Medicine Division of Pathobiology and Immunology Yale School of Medicine Case Western Reserve University Oregon Health Sciences University

Howard E. Gendelman, M.D. Tun-Hou Lee, D.Sc. Nancy Padian, Ph.D., M.P.H. David T. Purtilo Professor of Pathology and Professor of Virology Executive Director Microbiology Department of Immunology and Infectious Women’s Global Health Imperative Department of Pathology and Microbiology Diseases RTI International University of Nebraska Medical Center Harvard School of Public Health Professor, Department of Obstetrics, Gynecology and Reproductive Sciences Nancy L. Haigwood, Ph.D. Michael J. Leibowitz, M.D., Ph.D. and Department of Epidemiology and Biostatistics Director and Senior Scientist Professor University of California, San Francisco Division of Pathobiology and Immunology Department of Molecular Genetics and Oregon National Primate Research Center Microbiology Savita Pahwa, M.D. University of Medicine and Dentistry of New Director Daria Hazuda, Ph.D. Jersey-Robert Wood Johnson Medical School Microbiology and Immunology Vice President of Virus and Cell Biology Leonard M. Miller School of Medicine Department of Antiretroviral Research, Molecular Robert J. Levine, M.D. University of Miami Endocrinology, Virus and Cell Support, and Professor of Medicine Medicinal Chemistry Center for Interdisciplinary Research on AIDS Tristram G. Parslow, M.D., Ph.D. Merck Research Laboratories Yale University William Patterson Timmie Professor and Chair Department of Pathology and Laboratory Medicine Charles H. Hinkin, Ph.D. Mathias Lichterfeld, M.D. Emory University School of Medicine Associate Professor Assistant Professor of Medicine Department of Psychiatry and Biobehavioral Department of Medicine Deborah Persaud, M.D. Science Massachusetts General Hospital Associate Professor and Director University of California School of Medicine Infectious Disease Fellowship Program Judy Lieberman, M.D., Ph.D. Department of Pediatrics David Ho, M.D. Senior Investigator The Johns Hopkins University Scienti c Director, Chief Executive Of cer Immune Disease Institute Aaron Diamond AIDS Research Center Professor of Pediatics Matija Peterlin, M.D. Harvard Medical School Professor of Medicine, Microbiology and Thomas J. Hope, Ph.D. Immunology Professor H. Kim Lyerly, M.D. Department of Medicine Department of Cell and Molecular Biology Professor in Surgery, Immunology, Pathology University of California, San Francisco Northwestern University Duke Comprehensive Cancer Institute Feinberg School of Medicine Duke University Medical Center Vicente Planelles, Ph.D. Professor Shiu-Lok Hu, Ph.D. Frank Maldarelli, M.D., Ph.D. Department of Pathology, Microbiology and Professor Investigator Immunology School of Pharmacy HIV DRP Host-Virus Interactions Branch University of Utah University of Washington National Cancer Institute National Institutes of Health Lynn Pulliam, Ph.D. Jonathan Karn, Ph.D. Professor Reinberger Professor, Chair David M. Margolis, M.D. Department of Laboratory Medicine and Medicine Molecular Biology and Microbiology Professor of Microbiology, Medicine and Public University of California, San Francisco Case Western Reserve University Health Veterans Affairs Medical Center School of Medicine Fatah Kashanchi, Ph.D. University of North Carolina at Chapel Hill Lee Ratner, M.D., Ph.D. Director of Research Professor National Center for Biodefense and Infectious Martin H. Markowitz, M.D. Department of Medicine Diseases Staff Investigator Washington University School of Medicine George Mason University Aaron Diamond AIDS Research Center Andrew Rice, Ph.D. Vineet KewalRamani, Ph.D. Elena Martinelli, Ph.D. Professor Chief, Model Development Section Senior Research Investigator Department of Molecular Virology and HIV Drug Resistance Program HIV and AIDS Program USA Microbiology National Cancer Institute Population Council Baylor College of Medicine National Institutes of Health Kenneth Hugh Mayer, M.D. Melissa Robbiani, Ph.D. Richard Kornbluth, M.D., Ph.D. Infectious Disease Attending & Director of HIV Senior Scientist and Director of Biomedical HIV President and Chief Scienti c Of cer Prevention Research Research Multimeric Biotherapeutics, Inc. Beth Israel Deaconess Medical Center Center for Biomedical Research Professor of Medicine Population Council Richard A. Koup, M.D. Harvard Medical School Chief, Immunology Laboratory Medical Research Director, Co-Chair Ruth M. Ruprecht, M.D., Ph.D. Vaccine Research Center The Fenway Institute/Fenway Health Professor of Medicine National Institute of Allergy and Infectious Department of Cancer Immunology and AIDS Diseases Joseph M. McCune, M.D., Ph.D. Dana-Farber Cancer Institute and National Institutes of Health Professor of Medicine Harvard Medical School Division of Experimental Medicine Nathaniel R. Landau, Ph.D. University of California, San Francisco Karl Salzwedel, Ph.D. Professor Program Of cer Department of Microbiology Donna Mildvan, M.D. Pathogenesis and Basic Research Branch, New York University School of Medicine Chief, Division of Infectious Diseases Basic Sciences Program, Division of AIDS Department of Medicine National Institute of Allergy and Infectious Alan L. Landay, Ph.D. Beth Israel Medical Center Diseases Professor and Associate Chairman National Institutes of Health Department of Immunology and Microbiology Rush-Presbyterian-St.Lukes’s Medical Center

18 Frederick A. Schmitt, Ph.D. PROGRAM ADVISORY Rowena Johnston, Ph.D. Associate Professor Vice President and Director, Research Departments of Neurology, Psychiatry and COUNCIL Psychology Jeffrey Laurence, M.D. University of Kentucky Medical Center Senior Scienti c Consultant for Programs

Gerald Schochetman, Ph.D. Mervyn F. Silverman, M.D., M.P.H. (Chairman) John F. Logan, Ph.D., J.D. Director, AIDS Research and Retrovirus Discovery President Vice President and General Counsel Abbott Laboratories Mervyn F. Silverman Associates, Inc. AnnMari Shannahan Vice President, Public Information Robert Turner Schooley, M.D. David E. Bloom, Ph.D. (Co-Chairman) Academic Vice Chair Department of Global Health and Population Annette Sohn, M.D. Professor and Head Harvard School of Public Health Vice President and Director, TREAT Asia Department of Medicine/Division of Infectious Diseases University of California, San Diego Mario Stevenson, Ph.D. (Co-Chairman) Janet Siliciano, Ph.D. Assistant Professor Professor of Medicine School of Medicine Chief, Division of Infectious Diseases The Johns Hopkins University Leonard M. Miller School of Medicine University of Miami Robert Siliciano, M.D., Ph.D. Professor of Medicine, Molecular Biology, and Tim Brown, Ph.D. Genetics Senior Fellow School of Medicine The East-West Center The Johns Hopkins University Daria J. Hazuda, Ph.D. Gail Skowron, M.D. Vice President of Scienti c Affairs for Associate Professor of Medicine Infectious Disease Department of Medicine, Division of Infectious Merck & Company, Inc. Diseases Roger Williams Medical Center Kenneth H. Mayer, M.D. Infectious Disease Attending & Director Leonidas Stamatatos, Ph.D. of HIV Prevention Research Full Member and Director of Viral Vaccines Program Beth Israel Deaconess Medical Center Seattle Biomedical Research Institute Visiting Professor of Medicine Harvard Medical School Klaus Strebel, Ph.D Medical Research Director Chief The Fenway Institute/Fenway Health Viral Biochemistry Section, Laboratory of Molecular Microbiology Jeffrey L. Sturchio, Ph.D. National Institute of Allergy and Infectious Senior Partner Diseases, National Institutes of Health Rabin Martin Visiting Scholar Ernest F. Terwilliger, Ph.D. The Institute for Applied Economics, Assistant Professor Global Health and the Study of Business Beth Israel Deaconess Medical Center Enterprise, Johns Hopkins University Member of The Council on Foreign Relations Barbara Visscher, M.D., Dr.P.H. Professor of Epidemiology Phill Wilson Department of Epidemiology Chief Executive Of cer and President University of California, Los Angeles The Black AIDS Institute David Vlahov, Ph.D. Director Center for Urban Epidemiologic Studies New York Academy of Medicine

David J. Volsky, Ph.D. MANAGEMENT GROUP Professor and Director Department of Pathology and Medicine St. Luke’s-Roosevelt Hospital Center and Columbia University Kevin Robert Frost Chief Executive Of cer Steven S. Witkin, Ph.D. Professor and Director Anthony Ancona Department of Obstetrics and Gynecology Vice President and Director, Human Resources Weill Medical College of Cornell University Susan J. Blumenthal, M.D., M.P.A. Peter R. Wolfe, M.D. Senior Policy and Medical Advisor Associate Clinical Professor University of California, Los Angeles Gregory Boroff, C.A.E., C.F.R.E. Vice President and Director, Development Richard T. Wyatt, Ph.D. Chris Collins, M.P.P. Professor of Immunology Vice President and Director, Public Policy IAVI Center for Neutralizing Antibodies The Scripps Research Institute Bradley Jensen Chief Financial Of cer

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