Sample test questions

INTEGRATED TEST EXAM “Krok 1” Pharmacy

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Аналiтична хiмiя 2

1. What titrimetric method of analysis A. Rotation angle of a polarized light beam requires the use of both external and B. Refractive index internal indicators? C. Absorption coefficient of a polarized light beam in the solution A. Nitritometry D. Light beam dispersion in the solution B. Alkalimetry E. Optical density of the solution C. Complexometric titration D. Permanganatometry 7. Concentration of ethyl alcohol in tinctures E. Argentometry and some other dosage forms can be determined by means of refractometry. 2. A solution contains calcium, barium, For this purpose the following should be aluminium, potassium, and sodium cations. measured: Into this solution a small amount of ammonium hydroxide and alizarin solution A. Solution refractive index was added, which resulted in production of B. Rotation angle of a light polarization red precipitate. What ion was detected as plane the result of this reaction? C. Angle of total internal reflection of a light beam A. Aluminium D. Light beam incidence angle B. Calcium E. Light beam refraction angle C. Barium D. Potassium 8. Ammonium thiocyanate solution was E. Sodium added into the solution being studied. The resulting solution colored red. This 3. Select an indicator for argentometric analytical effect indicates the presence of determination of chloride ions using the the following cation: Mohr method: A. Iron(III) A. Potassium chromate B. Mercury(II) B. Diphenylcarbazone C. Silver C. Eosin D. Mercury(I) D. Fluorescein E. Lead(II) E. Methyl red 9. What reference electrode should be 4. Quantitative determination of copper used for potentiometric determination in a salts by means of photometric titration solution that contains ammonia and sodium should be conducted according to the hydroxide? calibration graph that is built within the following coordinates: A. Glass B. Platinum A. Optical density - concentration C. Silver B. Optical density - temperature D. Silver chloride C. Optical density - liquid layer thickness E. Zinc D. Light absorption intensity - wavelength E. Optical density - wavelength 10. When barium chloride solution was added into the solution being studied, it 5. 2M solution of HCl was added into resulted in a white precipitate that was acid- the solution being studied, which resulted and alkali-insoluble, which indicates that in formation of white precipitate that this solution contains: turned black when processed with ammonia solution. What cation is present in this A. Sulfate ions solution? B. Chloride ions C. Nitrate ions 2+ A. Hg2 D. Permanganate ions B. Ag+ E. Iron(II) ions C. Pb2+ D. Ba2+ 11. What laboratory glassware is used in E. Mg2+ titrimetric methods of analysis to measure out a precise volume of a titrant? 6. What should be measured during quantitative determination of glucose by A. Burette means of polarimetry? B. Pipette C. Volumetric flask D. Measuring cylinder E. Measuring glass 12. Quantitative content of oxalic Аналiтична хiмiя 3 acid can be determined by means of in potentiometric analysis of a medicinal permanganatometry. How to determine the substance? equivalence point for this kind of titration? A. Silver chloride A. When titrate changes its color after B. Glass another drop of working solution is added C. Quinhydrone B. With redox indicator diphenylamine D. Antimony C. With pH indicator E. Zinc D. With specific indicator E. With adsorption indicator 18. Why is there no group reagent for the cations of the 1st analytical group (acid-base 13. Specify what method of redox titration cassification)? requires the use of specific indicator - starch -tofix the end point: A. Most of their salts are water-soluble B. They have close ionic radii A. Iodometry C. They have large ionic radii B. Permanganatometry D. They can form soluble bases C. Nitritometry E. They belong to biologically important D. Cerimetry elements E. Bromatometry 19. What working solutions (titrants) are 14. To separate cations of the 6th used in Volhard method (precipitation analytical group from cations of the 5th titration)? analytical group (acid-base classification), the following is used: A. AgNO3 and NH4SCN B. H2SO4 and NaOH A. Excess ammonia solution C. Na S O and K[I ] B. Excess sodium hydroxide solution 2 2 3 3 D. KMnO4 and KBrO3 C. Excess sulfuric acid solution E. HClO and KOH D. Acetic acid solution 4 E. Silver nitrate solution 20. The third analitycal group of cations (acid-base classification) includes Ca2+, 15. To determine mass-volume fraction 2+ 2+ of ammonia in a solution, the following Sr , Ba . What acid can function as a solution should be used: precipitator agent (group reagent) for these cations? A. Hydrochloric acid B. Sulfuric acid A. H2SO4 C. Potassium permanganate B. HNO3 D. Iodine C. HCI E. Sodium hydroxide D. CH3COOH E. HCIO4 16. Pharmacopoeia reaction to determine benzoate ions requires interaction with the 21. Reaction of sodium ions with potassium solution of: hexahydroxoantimonate(V) in neutral medium produces precipitate. Specify the A. Iron(III) chloride colorofthisprecipitate: B. Potassium chloride C. Resorcin A. White D. Acetic anhydride B. Red E. Diphenylamine C. Yellow D. Green 17. What reference electrode can be used E. Blue Органiчна хiмiя 4

1. Which compound of those listed below 4. Salts and esters of oxalic acid are called: is a condensed arene? A. Oxalates A. B. Adipates C. Succinates D. Malonates E. Urates B. 5. What test is used for identification of uric acid and other compounds with purine nucleus?

C. A. Murexide reaction B. Silver mirror reaction C. Lucas reagent D. Fehling reagent E. Copper mirror reaction D. 6. Select the compound with both pyrrole and pyridine nitrogen atoms from those given below: E. A. Theophylline

2. Specify the Wurtz reaction among those given below: B. 2-Aminopyridine A.

B. C. Pteridine

C.

D. Pyrimidine

D.

E. E. Pyridazine

3. Select the formula of diazonium salt: A. 7. What reagent allows distinguishing between maltose (a reducing disaccharide) and sucrose (a non-reducing disaccharide)? A. Tollens reagent B. B. NaOH C. FeCl3 D. Br2 E. K4[Fe(CN6)]

C. C6H5 − N = O 8. Specify the name of the alkene given D. C6H5 − NH − C(O) − CH3 below according to the IUPAC substitutive E. (CH3)2N − N = O nomenclature: Органiчна хiмiя 5

− − − CH3 CH CH=C CH3 A. | |

C2H5 CH3

A. 2,4-Dimethyl-2-hexene B. 4-Ethyl-2-methyl-2-pentene B. C. 2-Ethyl-4-methyl-3-pentene D. 3,5-Dimethyl-4-hexene E. 4-Ethyl-2-methyl-3-pentene

9. Cellulose hydrolysis produces the C. following disaccharide: A. Cellobiose B. Maltose C. Sucrose D. Glucose D. E. Lactose

10. Transformation C2H4 (alkene) −→ C2H6 (alkane) occurs during the following reaction:

A. Hydrogenation E. B. Dehydrogenation C. Dehydration D. Hydration E. Dimerization 11. What type of bonds participates in creation of both linear and cyclic carboxylic 15. Which of the compounds given below is acid associates in the form of dimers? an aromatic one? A.

A. Hydrogen bonds B. Ionic bonds B. C. Polar covalent bonds D. Nonpolar covalent bonds E. Donor-acceptor bonds 12. The end-product of heating bromoethane with aqueous solution of potassium C. hydroxide is:

H2O H3C − CH2 − Br + KOH −−−→ ? A. Ethanol D. B. Ethane C. Ethene D. Ethanoic acid E. Diethyl ether 13. Name the product of starch hydrolysis: A. Glucose E. B. Fructose C. Mannose D. Ribose E. Galactose 16. Which of the listed monosaccharides is a 14. What is the formula of salicylic acid? ketose? Органiчна хiмiя 6

A. Fructose A. Benzimidazole B. Mannose B. Benzene C. Glucose C. Thiazole D. Galactose D. Pyridine E. Ribose E. Pyrimidine 17. Fructose is a monosaccharide, glucose 19. Which formula corresponds with β-D- isomer. In medicine it is used in treatment glucopyranose? of hepatic disorders and as a part of special diets. Which formula corresponds with D- A. fructose? A.

B.

B. C.

C. D.

D. E.

20. What compound is synthesized by means E. of beta-picoline oxidation?

A. Nicotinic acid B. Benzoic acid 18. Dibazol (Bendazol) is a hypotensive C. Uric acid antispasmodic drug. Its mechanism D. Barbituric acid of action is based on its ability to E. Ascorbic acid block phosphodiesterase type 4 enzyme 21. What compound will be produced as activity. This drug contains the following the result of toluene chlorination in the heterocyclic compound: presence of FeCl3 catalyst? Органiчна хiмiя 7

A.

B.

C.

D.

E. Фiзична та колоїдна хiмiя 8

1. What value determines the degree A. Vapour condensation and solvent of influence that foreign ions have on the substitution potential of an ion-selective electrode? B. Chemical condensation and peptization C. Dispergation and peptization A. Selectivity coefficient D. Ultrafiltration and peptization B. Diffusion coefficient E. Ultrafiltration and vapour condensation C. Activity coefficient D. Electrical conductivity coefficient 8. If in the process of molecular adsorption E. Osmotic coefficient the solute is being adsorbed more than the solvent, then the following occurs: 2. Name the process of spontaneous adhesion of drops in an emulsion to each A. Positive adsorption other: B. Negative adsorption C. No adsorption A. Coalescence D. Selective adsorption B. Flocculation E. Ion adsorption C. Sedimentation D. Flotation 9. What device is used to measure surface E. Coagulation tension of a liquid? 3. Enzymes are widely used as drugs in A. Stalagmometer pharmacy. What is the main difference B. Areometer that separates enzymes from non-biological C. Viscometer catalysts? D. Calorimeter E. Nephelometer A. High specificity and selectivity B. High universality 10. Sedimentation is characteristic of the C. Low universality following systems: D. High dispersion E. High homogeneity A. Suspensions B. Solutions of high-molecular compounds 4. Name the structural unit of a colloidal C. Nonelectrolyte solutions solution of a medicinal substance: D. Electrolyte solutions E. Foams A. Micelle B. Molecule 11. Under certain conditions, solutions of C. Atom high-molecular substances can lose their D. Ion flowability, meaning that the bonds begin E. Zwitterion to form between macromolecules, leading to the formation of a spatial grid. Name this 5. Surfactants and high-molecular process: compounds are added into concentrated emulsions to stabilize them. These A. Gel formation substances are: B. Coacervation C. Condensation A. Emulsifiers D. Coagulation B. Activators E. Peptization C. Catalysts D. Solvents 12. Collagen, gelatin, keratin, and myosin E. Absorbents are the proteins that are formed with peptide bonds and resemble long threads 6. Specify the order of acetone breakdown in shape. Name this type of proteins: reaction: A. Fibrillar proteins CH3COCH3 = C2H4 + H2 + CO B. Globular proteins C. Chain proteins A. First D. Structured proteins B. Second E. - C. Third D. Zero 13. Name the ability of high-molecular E. Fractional compounds to prevent precipitation of lyophobic sols and deposition of cholesterol 7. What two methods of obtaining a disperse plaques on the vessel walls: system can be characterized as physical condensation? Фiзична та колоїдна хiмiя 9

A. Colloid protection 16. Name the process of removing one or B. Coacervation several substances from a complex system C. Sedimentation by means of a selective solvent: D. Coagulation E. Thixotropy A. Extraction B. Evaporation 14. Saline solution with 0.9% of NaCl in C. Crystallization relation to blood serum can be characterized D. Dispersion as: E. Condensation A. Isotonic 17. In medical and pharmaceutical practice B. Hypotonic the phenomena of adsorption, wetting, and C. Hypertonic adhesion are regularly observed. Name this D. Colloidal group of phenomena: E. - A. Surface phenomena 15. Helmholtz energy is a direction criterion B. Electrokinetic phenomena of a spontaneous process at a constant: C. Molecular-kinetic phenomena D. Optical phenomena A. Temperature and volume E. Physico-chemical phenomena B. Temperature and pressure C. Entropy and volume D. Internal energy and volume E. Entropy and pressure Патологiчна фiзiологiя 10

1. I.I.Mechnikov, when studying polycyclic aromatic hydrocarbon) was daily inflammatory process, described a certain applied to a dehaired patch of skin of the order that is characteristic of leukocyte animal. What method is used for tumor migration to the inflammation focus. The modelling in this case? cells emigrate to the focus in the following order: A. Induction B. Transplantation A. Neutrophilic granulocytes, monocytes, C. Explantation lymphocytes D. Ionizing radiation B. Monocytes, lymphocytes, neutrophilic E. Hormone administration granulocytes C. Neutrophilic granulocytes, lymphocytes, 7. After a surgery the patient presented with monocytes a severe pain syndrome. What change in the D. Monocytes, neutrophilic granulocytes, patient’s hormonal status is most likely in lymphocytes this case? E. Lymphocytes, monocytes, neutrophilic granulocytes A. Increased catecholamine production B. Insulin hypersecretion 2. A patient has developed anuria. Blood C. Decreased ACTH production pressure is 50/20 mm Hg. What process D. Decreased production of glucocorticoids of uropoiesis caused acute decrease of E. Decreased production of urination? mineralocorticoids A. Glomerular filtration 8. A 9-year-old child due to acute bronchitis Obligatory reabsorption developed elevated body temperature up to B. o C. Facultative reabsorption 38.5 C that lasted for a week and was then D. Tubular secretion followed by a drop in the temperature down o E. - to 37.0 C. What mechanism is leading at the 3rd stage of fever? 3. During lancing an abscess in the oral cavity, it produces a yellow-green A. Peripheral vasodilation discharge. What cells are always present and B. Increased heat production predominant in the purulent exudate? C. Development of chills D. Increased diuresis A. Neutrophils E. Increased respiration rate B. Eosinophils C. Basophils 9. One hour after a child took polyvitamins D. Lymphocytes in the dosage form of a syrup, the child E. Erythrocytes developed a markedly itching urticaria-type rash all over the body. What type of allergic 4. People, who were in the building during a response can be characterized by this sign? fire, suffer from carbon monoxide poisoning. What type of hypoxia can be observed in this A. Anaphylactic case? B. Immune complex C. Cytotoxic A. Hemic D. Delayed-type hypersensitivity B. Circulatory E. Autoallergic C. Hypoxic D. Respiratory 10. A patient develops prolonged E. Tissue hemorrhages and hemorrhages into the muscles and joints as a result of any 5. A 42-year-old patient presents with microtraumas. In the blood there is a skin pallor, weakness, and enlarged lymph deficiency of the VIII plasma factor of blood nodes. In peripheral blood: leukocytosis, coagulation. What disease of blood system no intermediate forms of leukocytes is observed in this patient? (”leukemic hiatus”), accelerated ESR. What disease can be suspected in this case? A. Hemophilia A B. B12 and folate deficiency anemia A. Acute leukemia C. Iron-deficiency anemia B. Chronic leukemia D. Thrombocytopenic purpura C. Erythromyelosis E. Vaquez disease (polycythemia vera) D. Neutrophilic leukocytosis E. Leukemoid reaction 11. A man received a radiation dose of 30 Gy. He presents with necrotic angina, 6. To reproduce Ehrlich carcinoma in a disorders of the gastrointestinal tract. Blood rabbit, a certain amount of benzpyrene (a tests revealed anemia, leukopenia and Патологiчна фiзiологiя 11 thrombocytopenia. What stage of acute 15. What is the mechanism of indirect action radiation sickness is observed in the patient? of ionizing radiation on cells? A. Manifest illness stage A. Formation of large amount of free radicals B. Prodromal stage B. Chromosome rupture C. Latent stage C. Damage to the cytoplasmic membrane D. Recovery D. Swelling of organelles E. - E. Activation of protein biosynthesis 12. A 54-year-old man requested a 16. A couple came to the genetic pharmacist’s advice on drug prescription. consultation for their newborn child to The patient has 4-year-long history of be examined. Karyotype test detects an chronic glomerulonephritis and 2-year-long additional chromosome in the 21 pair. What history of persistent hypertension. What diagnosis can be made? substance synthesized in the kidneys has important role in development of arterial A. Down syndrome hypertension? B. Edwards syndrome C. Patau syndrome A. Renin D. Turner syndrome B. Nitric oxide E. Klinefelter syndrome C. Aldosterone D. Histamine 17. After a physical exertion a person E. Catecholamines develops extra (premature) cardiac contractions. What type of arrhythmia is it? 13. Examination of a 45-year-old man, who for a long time kept to a vegetarian plant- A. Extrasystole based diet, revealed him to have negative B. Sinus tachycardia nitrogen balance. What peculiarity of his C. Sinus bradycardia diet has caused such developments? D. Ventricular fibrillation E. Paroxysmal tachycardia A. Insufficient protein content B. Insufficient fat content 18. A 55-year-old man came to a doctor C. Insufficient vitamin content with complaints of acute pain in his big toes. D. Excessive water content Meat and wine are always present in his diet. E. Excessive carbohydrate content The doctor suspects gout. What substance must be measured in the patient’s blood to 14. A 23-year-old man came to the infectious confirm this diagnosis? diseases department with complaints of abdominal distension and diarrhea. He was A. Uric acid diagnosed with lambliasis. What type of B. Urea leukocytosis is characteristic of this disease? C. Lactate D. Bilirubin A. Eosinophilic E. Ketone bodies B. Neutrophilic C. Basophilic D. Lymphocytic E. Monocytic Бiологiчна хiмiя 12

1. A patient suffers from diarrhea, 7. Primary structure of nucleic acids is a dermatitis, and dementia. What vitamin is polynucleotide chain that has a certain likely to be deficient in this patient, causing composition and order of the nucleotides. the patient’s condition? What bonds stabilize this structure? A. Nicotinic acid A. 3
, 5
-phosphodiester B. Vitamin K B. Peptide C. Vitamin D C. Glycosidic D. Tocopherol D. Disulfide E. Retinol E. Amide 2. An unconscious patient was brought into 8. Gout develops when purine nucleotide the intensive care unit. Acetone breath, metabolism is disturbed. A doctor acute hyperglycemia, and ketonemia are prescribed the patient allopurinol that is a detected. What complication of diabetes competitive inhibitor of: mellitus occurred in this case? A. Xanthine oxidase A. Diabetic coma B. Succinate dehydrogenase B. Hypoglycemic coma C. Alcohol dehydrogenase C. Cataract D. Lactate dehydrogenase D. Acute acetone poisoning E. Hexokinase E. Nephritis 9. Cocarboxylase is used in medicine as a 3. Serum total protein is one of metabolic pharmaceutical preparation for treatment indicators. What reaction is usually used in of myocardial dystrophy and conditions that clinical laboratories to measure this value? affect muscles and peripheral CNS. What vitamin is a component of this preparation? A. Biuret B. Ninhydrin A. B1 C. Xanthoproteic B. B2 D. Fohl C. B6 E. Nitroprusside D. C E. B12 4. Thyroid gland produces a hormone that regulates Ca2+ levels in blood, which 10. A patient complains of polyuria. Urine facilitates mineralization of bone tissue. test detects no pathologic components, but What hormone has such an effect? urine specific gravity is abnormally low. What hormone secretion is likely to be A. Thyrocalcitonin disturbed in this patient? B. Thyroxin C. Triiodothyronine A. Vasopressin D. Dopamine B. Somatotropin E. Adrenaline C. Thyrotropin D. Insulin 5. A patient is diagnosed with acute E. Cortisol pancreatitis. For diagnostic purpose it is necessary to measure the activity of the 11. A patient with hyperproduction of following enzyme in the patient’s blood: thyroid hormones has been prescribed Merkazolilum. This drug inhibits the A. Amylase following enzyme participating in B. Aldolase iodothyronine synthesis: C. LDH D. Creatine kinase A. Iodide peroxidase E. Pepsin B. Aromatase C. Reductase 6. What enzyme allows for synthesis of D. Decarboxylase various genes from template-RNA to E. Aminotransferase DNA in genetic engineering (this enzyme catalyzes the process discovered in RNA- 12. Ascorutin vitamin preparation is used viruses)? for treatment of bleeding gums and punctate hemorrhages. What vitamin does this A. Reverse transcriptase preparation contain? B. Exonuclease C. DNA-ligase D. Helicase E. Endonuclease Бiологiчна хiмiя 13

A. C A. Histidine B. K B. Glycine C. D C. Asparagine D. A D. Ty r o s i n e E. E E. Alanine 13. A man developed high plasma iron levels 16. Cholesterol synthesis inhibitors are used due to intensified hemolysis of erythrocytes. as antiatherosclerotic drugs. Select one such What plasma protein transports iron? drug from the list: A. Transferrin A. Lovastatin B. Interferon B. Sulfanilamide C. Ceruloplasmin C. Benzylpenicillin D. Albumin D. Pancreatin E. Histone E. Chloramphenicol 14. In case of hypovitaminosis of a certain 17. Aspartame is used as a sweetener and in vitamin, disturbed proliferation of epithelial treatment of diabetes mellitus. What amino and connective tissue can be observed. acid does it contain? Patients with this type of hypovitaminosis usually present with impaired vision and A. Aspartic acid spatial orientation. Name this vitamin: B. Glutamic acid C. Valine A. Retinol D. Leucine B. Cholecalciferol E. Methionine C. Tocopherol D. Riboflavin 18. Hemoglobin break-up begins in the E. Pyridoxine cells of reticuloendothelial system. What enzyme catalyzes the reduction reaction of 15. Antihistamines are used in treatment biliverdine into bilirubin? of allergic responses, because histamine functions as an allergic response mediator. A. Biliverdine reductase Name the amino acid from which histamine B. Beta-glucuronidase is produced: C. Xanthine oxidase D. Heme oxygenase E. Hexokinase Фармацевтична ботанiка 14

1. Plants that grow in moderately A. Raphides humid conditions belong to the following B. Druses ecological group: C. Styloids D. Twinned crystals A. Mesophytes E. Crystalline sand B. Hydrophytes C. Hygrophytes 7. Name the male gametophyte of flowering D. Xerophytes plants: E. Succulents A. Pollen grains 2. Among the trees of Fabaceae family there B. Carpel is an early-flowering melliferous plant with C. Embryo sac pinnately compound leaves, spine-shaped D. Ovule stipules, and white fragrant flowers arranged E. Nucellus in hanging racemes. Name this plant: 8. A gastric tea contains small oval brown A. Robinia pseudoacacia lignified cone-shaped plant parts up to 1.5 B. Armeniaca vulgaris cm in length that can be identified as: C. Aesculus hippocastanum D. Aronia melanocarpa A. Aggregate fruits of alnus E. Quercus robur B. Larch cones C. Cypress cones 3. Select a Brassicaceae family plant that D. Berry-like juniper cones contains glycosides similar in action to those E. Platycladus orientalis cones obtained from foxglove: 9. A diagnostic feature important for A. Erysimum canescens correct identification of pine species is the B. Arctostaphylos uva-ursi number of needles on the short shoots C. Urtica dioica (brachyblasts). Pinus sylvestris has the D. Polygonum aviculare following number of needles on its short E. Primula officinalis shoots: 4. Among harvested plants there was A. 2 Capsella bursa-pastoris, which can be B. 5 characterized as follows: C. 3 D. 8 A. Annual plant, basal leaves - pinnatisected E. Many or pinnatipartite, fruit - small triangular heart-shaped silique 10. In pharmaceutical manufacturing, rutin B. Biennial plant, basal leaves - pinnatilobate, and quercetin are obtained from the flowers fruit - small round silique of a certain Fabaceae family plant. Name C. Perennial plant, basal leaves - entire-kind, this plant: fruit - cylindric silique D. Annual plant, basal leaves - compound, A. Styphnolobium japonicum fruit - segmented silique B. Robinia pseudoacacia E. Biennial plant, basal leaves - membranous, C. Caragana arborescens fruit - small winged heart-shaped silique D. Astragalus piletocladus E. Acacia dealbata 5. Berberis vulgaris has spines that are modifications of: 11. A cough tea contains comminuted roots of a plant. The roots are colored bright A. Leaves yellow and taste sweet. They were identified B. Stipules as roots of the following plant: C. Petioles D. Stems A. Glycyrrhiza glabra E. Rachises B. Althaea officinalis C. Acorus calamus 6. In monocotyledonous plants metabolism D. Va l e r i a n a o fficinalis end-products are often represented by E. Sanguisorba officinalis multiple needle crystals of calcium oxalate arranged in clusters. Name these structures: 12. Nuciform fruits include a certain type of one-seeded fruit that does not burst when ripe. Its base is enclosed in a cup-shaped cupule formed by the broad part of the peduncle to which the flower was attached. Name this type of fruit: Фармацевтична ботанiка 15

A. Acorn 15. One of the important diagnostic features B. Nut of garden sage and motherwort is their C. Nutlet shape of corolla. Their flowers have the D. Samara following type of corolla: E. Caryopsis A. Bilabiate 13. Plantago major inflorescence grows at B. Thimble-shaped the apex, its rachis is long, with sessile C. Funnelform flowers. Name this type of inflorescence: D. Pseudoligulate E. Ligulate A. Spike B. Panicle 16. Rhizome of an Asteraceae family C. Spadix species is polycephalous, succulent, has D. Capitulum lysigenous cavities, accumulates inulin. Such E. Thyrse underground organ is characterisic of: 14. Upon examination of a flower it is A. Inula helenium determined to have one pistil made up of B. Hyoscyamus niger single free carpel. Therefore, this gynoecium C. Digitalis grandiflora can be identified as: D. Sorbus aucuparia E. Helianthus annuus A. Monocarpous B. Apocarpous C. Lysicarpous D. Paracarpous E. Syncarpous Мiкробiологiя 16

1. To obtain bacterial exotoxins, A. Vector-borne transmission microorganisms are cultivated in a liquid B. Vertical transmission nutrient medum, into which the toxins C. Airborne droplet transmission are being discharged. What method allows D. Fecal-oral transmission clearing the medium of microorganisms, so E. Parenteral transmission that only pure exotoxins will remain in the medium? 6. A chemotherapeutic agent has bactericidal effect against streptococci, A. Filtration through bacterial filters staphylococci, bacilli, and clostridia. B. Boiling According to its action spectrum this drug C. Autoclaving belongs to the following group: D. Ultraviolet irradiation E. Application of disinfectants (Chloramine) A. Broad spectrum antibacterial agents B. Narrow spectrum antibacterial agents 2. In the course of bacteriological C. Broad spectrum antifungal agents examination of the feces of a patient with D. Antiviral agents diarrhea, a pure culture of slightly curved E. Antituberculous agents bacilli was obtained. In the microslide these microorganisms were arranged in clusters 7. It is known, that HIV infection leads resembling schools of fish. Cultivation in the to severe immunologic disturbances in alkaline medium (alkaline peptone water) the body that result in the development in six hours resulted in formation of a blue- of AIDS (acquired immune deficiency tinged film. These features are characteristic syndrome). What cells of the human body of the following causative agent: are the most susceptible to HIV infection? A. Vibrio cholerae A. T helper cells B. Colibacilli B. Hepatocytes C. Salmonellae C. Suppressor T cells D. Spirochetes D. Endotheliocytes E. Mycobacteria E. B lymphocytes 3. One day after eating meatballs in the 8. Microbe survival within environment is school canteen, several students came to the facilitated by spore formation. What genus nurse’s office complaining of stomachache, of microorganisms can be characterized as vomiting, high body temperature, and spore formers: diarrhea. One of the students was hospitalized in a severe condition. What A. Clostridium microorganisms can be the cause of this food B. Bacteroides toxicoinfection? C. Staphylococcus D. Peptococcus A. Salmonellae E. Peptostreptococcus B. Streptococci C. Clostridiae 9. To induce an artificially acquired active D. Shigellae immunity,a three-month-old child was given E. Meningococci orally a Sabin strain-based live cultural vaccine. This vaccine is used for prevention 4. For tetanus prevention a certain toxin of: is used. For 4 weeks this toxin is being A. Poliomyelitis neutralized with formaldehyde (0.4%) o B. Tuberculosis under the temperature of 39 C.Namethe C. Measles resulting preparation: D. Rubella A. Anatoxin E. Parotitis B. Immunoglobulin 10. After examination the child was C. Antitoxic serum diagnosed with scarlet fever. What D. Adjuvant microorganism is a causative agent of this E. Inactivated vaccine disease? 5. After examination the patient was A. Streptococcus diagnosed with tick-borne encephalitis. B. Staphylococcus What route of transmission is characteristic C. Meningococcus of this disease? D. Klebsiella E. Actinomycete 11. A ready-made drug was inoculated on Sabouraud’s agar and incubated under 22oC Мiкробiологiя 17 for 5 days. This nutrient medium was used arranged separately and in groups. What to determine the following: microorganisms were detected? A. Number of mold and yeast fungi A. Micobacterium tuberculosis B. Total number of bacteria B. Bacillus anthracis C. Presence of E. coli C. Salmonella typhi D. Presence of S. aureus D. Staphylococcus aureus E. Presence of Salmonella E. Bordetella pertussis 12. Seitz filters are widely used in laboratory 16. Sanitary-microbiological assessment of practice. What is their purpose? water quality in the water supply system conducted by the sanitary-epidemiological A. Sterilization by means of filtration station detected microorganisms indicative B. Disinfection of solutions of fecal contamination of water. What C. Measurement of water contamination microorganisms were detected? D. Growing of bacteriophages E. Virus destruction A. Escherichia coli B. Streptococcus agalactiae 13. Thermolabile medicinal preparation C. Haemophilus influenzae o for extemporal use was heated to 65 C D. Neisseria sicca thrice with intervals of one day between the E. Staphylococcus aureus heatings. What method of sterilization was used in this case? 17. Air contamination with pathological microorganisms can be anticipated by the A. Tyndallization presence of indicator bacteria. Specify B. Pasteurization the bacteria that indicate immediate C. Koch’s steam sterilization epidemiologic danger: D. Calcination E. Filtration A. Hemolytic streptococci B. Sarcinae 14. Many serological reactions require C. Mold fungi strictly aseptic conditions. What method of D. Yeast fungi sterilization is optimal for decontamination E. Micrococci of laboratory glassware? 18. It can be safely assumed that the infants A. Dry heat born from the mothers with the history of B. Tyndallization measles will not be affected by the measles C. Pasteurization outbreak during their stay in the maternity D. Filtration ward. What classes of antibodies provide the E. Calcination infants with the resistance to this disease? 15. During microscopy of a smear A. IgG made from the sputum sample and B. IgA stained according to the Ziehl-Neelsen C. IgD technique, the medical laboratory scientist D. IgM detected bright red acid-fast bacilli E. IgE Фармакологiя 18

1. During a surgery, tubocurarin chloride A. Nitroglycerine was used as a muscle relaxant. What B. Digoxin antagonist should the patient be given to C. Amiodarone restore spontaneous breathing? D. Lisinopril E. Corglycon A. Proserin (Neostigmine) B. Dithylin (Suxamethonium) 7. Name the ability of a drug to accumulate C. Cytitone (Cytisine) within the patient’s body: D. Aethimizole (Methylamide) A. Cumulation E. Benzohexonium (Hexamethonium) B. Antagonism C. Synergism 2. A patient, who has been taking D. Habituation phenazepam for a month, came to the E. Allergy pharmacy. He insists that he needs to buy two more packages of this drug, because 8. You work in the pharmacy located at the without it he feels unwell. The side-effect of premises of the dermatovenerologic clinic. this drug that can be observed in this patient Consult an intern what antibiotic is a drug is based on the development of: of choice for treatment of syphilis: A. Addiction A. Benzylpenicillin sodium salt B. Idiosyncrasy B. Lincomycin hydrochloride C. After-effect C. Levorin sodium salt D. Cumulation D. Streptomycin sulfate E. To l e r a n c e E. Polymyxin M sulfate 3. Select the halogenated antiseptic that 9. A doctor has prescribed a nonsteroidal would be preferable for a child to pack in anti-inflammatory drug to relieve the first aid kit, when going to a summer inflammation and pain syndrome. Name this camp: drug: A. Iodine alcoholic solution A. Diclofenac sodium B. Brilliant green B. Glibenclamide C. Copper sulfate C. Loratadine D. Methylene blue D. Prednisolone E. Formaldehyde solution E. Calcium chloride 4. A medical student needs to choose 10. What is the most common side-effect of an adrenergic drug for treatment of inhaled corticosteroids? anaphylactic shock. What would you recommend? A. Oropharyngeal candidiasis B. Increased body mass A. Adrenaline hydrochloride C. Osteoporosis B. Clophelin (Clonidine) D. Subcapsular cataract C. Galazolin (Xylometazoline) E. Arterial hypertension D. Fenoterol E. Izadrin (Isoprenaline) 11. Treatment with sodium bromide resulted in development of bromism in the 5. What is the main mechanism of patient: rhinitis, cough, conjunctivitis, and benzylpenicillin bactericidal action on the skin rashes. What should the patient be coccal flora? prescribed to treat this condition? A. Disturbed synthesis of microbial cell wall A. Sodium chloride B. Inhibition of protein synthesis B. Potassium chloride C. Disturbed cytoplasmic membrane C. Sodium iodide permeability D. Calcium chloride D. Activation of macroorganism immune E. Sodium sulfate system E. Increased phagocytic activity of leukocytes 12. A patient with allergic rhinitis was prescribed loratadine. This drug belongs to 6. What drug can quickly stop an angina the following group of antiallergic agents: pectoris attack, when taken sublingually? A. H1-antagonists B. H2-antagonists C. Glucocorticoids D. Membrane stabilizers E. Leukotriene receptor antagonists Фармакологiя 19

13. A patient suffers from intense cough A. Aciclovir with production of viscous sputum. What B. Nystatin drug can thin the sputum and facilitate C. Atropine expectoration? D. Ranitidine E. Rifampicin A. Acetylcysteine B. Prenoxdiazine 18. Forced diuresis needs to be induced in C. Codeine phosphate a patient with acute medication poisoning. D. Glaucine What drug must be used for this purpose? E. Butamirate A. Furosemide 14. A patient with myocardial infarction was B. Strophantin receiving heparin as a part of the complex C. Progesterone therapy. With time the patient developed D. Bisacodil hematuria. What drug should be given as an E. Diphenhydramine antidote in this case? 19. Caffeine is one of the alkaloids contained A. Protamine sulfate in tea and coffee. Caffeine is contraindicated B. Aminocaproic acid in case of: C. Vicasol (Menadione) D. Fibrinogen A. Essential hypertension E. Neodicumarin B. Fatigue C. Hypotension 15. A patient with tracheitis was prescribed D. Depression of nervous activity a centrally acting antitussive drug that does E. Migraine not depress respiration, causes no addiction, and lowers blood pressure. Name this drug: 20. To quickly relieve the state of acute psychosis, the patient was prescribed a A. Glaucine hydrochloride rapid/short-acting psychotropic drug. Name B. Codeine phosphate this drug: C. Morphine hydrochloride D. Acetylcysteine A. Droperidol E. Prenoxdiazine B. Valerian extract C. Piracetam 16. What drug is used for treatment of D. Amitriptyline organophosphate poisoning? E. Caffeine and sodium benzoate A. Atropine sulfate 21. After ishemic stroke the patient was B. Aciclovir prescribed a drug to improve his intellectual C. Platyphylline functioning and memory. What drug should D. Metronidazole he obtain from the pharmacy? E. Izoniazid A. Piracetam 17. Select the drug with anti-herpesvirus B. Metoclopramide activity that can be used for prevention and C. Tabex (Cytisine) treatment of herpetic lesions on skin and D. Diphenin (Phenytoin) mucosa: E. -