9th EDITION 2017 CONFERENCE PROGRAMME www.ineip.org

ORGANISED BY A JOINT COLLABORATION WITH CONFERENCE PROGRAMME 2017 VENUE FLOOR PLAN 9th EDITION

VENUE Austria Trend FLOOR PLAN

Hotel Savoyen

WIEN Prinz von Savoyen Restaurant Restaurant TURIN Prinz von Savoyen Prinz von ROOM

P ROOM Wien aris Turin

1st floor

1st FLOORAustria Trend Hotel Savoyen

ground floor Atrium

Restaurant Prinz

von Savoyen

Bar Soissons

SPEAKERS'

ROOM

Laura Mancini

Lobby

REGISTRATION DESKS REGISTRATION

DESKS EXHIBITION & CATERING AREA

Foyer Mancini

FOYER MANCINI

Olympia Mancini 1A

POSTER AREA MANCINI & HOW TO HALL 1 SESSIONS

MANCINIOlympia Mancini 2 Olympia Olympia Mancini 1B Mancini MANCINI HALL 2

HALL 3A

3 A

Olympia MANCINIMancini

HALL 3B 3 B

CONFERENCE PROGRAMME 2017 TABLE OF CONTENTS 1 9th EDITION

TABLE OF CONTENTS

Page

Word of Welcome 3

Educational Highlights 4

Scientific Programme at a Glance 5

Conference General Information and Information for Speakers 12

Oral and Poster Presenters 13

Attendee Services 14

Discover Vienna 17

Supporting Organisations and Partners 18

Continuing Medical Education (CME) and Session Evaluations 23

Thursday 7th December: Sessions 25

Friday 8th December: Sessions 33

Saturday 9th December: Sessions 42

Professional Development Sessions from the Leadership Foundation for Higher Education 45

2nd Life Course Immunisation Focus Group - Friday 8th December 47

Abstracts 51

Speakers and Authors’ Index 119 CELEBRATING 10 YEARS OF EXCELLENCE IN PEDIATRICS Now in its 10th edition - December 2018

BLOCK 6-8 DECEMBER 2018 IN YOUR DIARY

1st 2nd 3rd 4th 5th 6th 7th 8th 9th EDITION EDITION EDITION EDITION EDITION EDITION EDITION EDITION EDITION 2009 2010 2011 2012 2013 2014 2015 2016 2017 FLORENCE LONDON ISTANBUL MADRID QATAR DUBAI LONDON LONDON VIENNA

Celebrating EIP’s 10th Edition Join us next December at this dynamic and interactive international pediatric Conference and help improve child health globally. Designed to equip healthcare professionals with the latest research, updates and best practice advice, helping you to improve your everyday practice. Remaining in Europe in 2018 and attracting hundreds of delegates from over 90 countries Over 90 internationally renowned speakers delivering 100+ sessions Plenary keynotes, classes, controversies debates and workshops Covering a broad range of topics across Neonatology, Pediatrics and Adolescent Medicine

ORGANISED BY Improving Child Health Globally CONFERENCE PROGRAMME 2017 WELCOME FROM CONFERENCE CHAIRS 3 9th EDITION

WELCOME FROM THE 2017 CONFERENCE CHAIRS

Dear Colleagues and Friends,

Welcome to the 9th Edition of the Annual Excellence in Pediatrics (EiP) Conference and thank you for joining us for what promises to be our most successful meeting to-date. For the first time in EIP’s history we are delighted to be in the beautiful city of Vienna. Please make the most of your inspiring surroundings and connect with your fellow delegates and colleagues from 85+ countries around the world.

TERENCE STEPHENSON As ever, we are very thankful that over 90+ of the leading experts in pediatrics, Chair of the General Medical neonatology, and adolescent health have agreed to present their latest research Council (GMC) in the UK and over the next 3 days in an eclectic mix of practical-learning sessions, lectures, Nuffield Professor of Child Health workshops, InFocus sessions, and masterclasses. We have never had such at the Institute of Child Health at a large conference faculty, so please make the most of their expertise and University College London, UK experience at every opportunity possible.

Collaboration is key to EIP and the 9th Edition is once again a truly collaborative effort held in conjunction with the Health Behaviour in School-aged Children (HBSC): WHO Collaborative Study, the WHO Collaborating Centre for International Child and Adolescent Health Policy based at the University of St Andrews School of Medicine, the Leadership Foundation for Higher Education and a host of other partners and supporters. We are very grateful to all our partners for their help and support in creating such an inspiring and practical conference programme.

In addition to the main conference, it’s great to see that 150+ abstracts have been accepted and EIP 2017 will feature over 100 posters and 9 hours of oral presentations. New research is critical for improving standards of care and we JOAN-CARLES SURIS would encourage you to view the posters located in Hall Mancini 3A during Institute of Social and Preventive the coffee and lunchbreaks and attend as many oral presentation sessions as Medicine and Department of possible. As well as being included in this onsite brochure, all accepted abstracts Pediatrics Lausanne University have been published by Cogent Medicine online as the final, definitive and Hospital, Switzerland citable version of the book of abstracts.

In parallel to the main conference sessions and oral presentations, EiP are also hosting the 2nd Life Course Immunisation Focus Group Meeting on Friday 8th December from 10:15-14:15 in the Wien Room on the first floor. This is an open meeting tasked with overcoming vaccine hesitancy across Europe and we would encourage you to join to help improve vaccinations rates across Europe. The full Focus Group agenda is available on pages 47-48.

Thank you for attending and we all hope that you enjoy EIP 2017 and look forward to meeting and working with you over the coming 3 days in Vienna and continuing to collaborate with you into 2018 and beyond.

JO INCHLEY HBSC International Coordinator, University of St Andrews, School of Medicine, UK

Improving Child Health Globally CONFERENCE PROGRAMME 2017 EDUCATIONAL HIGHLIGHTS 4 9th EDITION

EDUCATIONAL HIGHLIGHTS OF THE 2017 CONFERENCE

n 95+ scientific sessions across 5 parallel tracks in an inspiring mix of interactive Dear Conference Delegates, formats and workshop learnings, allowing you to tailor-make the conference to your needs. It gives me huge pleasure to introduce the 2017 scientific program for the 9th edition of the Excellence in Pediatrics n 20 conference sub-sections covering the latest trends and practice changes in Conference in Vienna. pediatrics (12 red sections), adolescent medicine (4 blue sections) and neonatology (2 green sections). As you will see the program follows the same overall structure adopted for the past 2 editions and there are n Presentations from over 90+ internationally renowned speakers, leading experts in pediatrics, neonatology, adolescent health, leadership and professional development. 20 sub-sections (groups of 3-4 presentations) over the 3 conference days covering the latest developments, trends n 10 practical workshops (purple sessions) providing hands-on advice that puts you at and practice changes in pediatrics (12 red sections), the centre of the interactive learning sessions. adolescent medicine (4 blue sections) and neonatology (2 green sections). In addition to the 20 subsections n 5 Spot the Early Signs Trainings – focused on spotting the signs of metabolic listed above, there are also 10 workshops, 7 professional disorders this year - with all recorded sessions, along with 20+ recorded webinars development sessions, 5 Spot the Early Signs training available online at: http://metabolic.diseases.spot-early-signs.org/ after the conference. courses, 3 briefings, a Masterclass and an InFocus n Two inspiring free-to-attend 120-minute Leadership Workshops session.  (dark green on the program) delivered by the Leadership Foundation for Higher Education, designed to improve the way you lead both as an individual and within your healthcare team. The colour coding and design of the program allows you to pick and choose the most relevant sections and sessions to n A free-to-attend 120 minute InFocus Session on the Influence of Microbiota on allow you create your own personalised conference agenda aspects on child health designed to provide a practical overview and update on the from over 80 hours of conference content. To help you latest developments. choose the right session for your needs, each one has a clear set of 3 learning objectives that are detailed in the full n An excellent new 90 minute Presentation Skills for Healthcare Professionals version of the program on pages 24-48. These objectives Workshop looking at how You can lecture an audience to knowledge (sometimes), but will allow you to have a much better understanding of you must inspire it to think! what you will glean from each session. In addition, you n A free-to-attend 120 minute Masterclass on the Essentials of Invasive and Non- will be asked to evaluate each session through delegate invasive ventilation in Newborns designed to cater for pediatricians looking to gain a evaluation cards that will help EiP to constantly improve deeper understanding. the quality of the sessions and build and improve the conference for the 10th edition next year. n Two free-to-attend 60-minute Publishing and Writing Scientific Papers Professional Developments sessions designed to improve your chances of getting I would encourage you to actively participate and your paper published. interactive with over 90+ global expert speakers and the n The 2nd Life Course Immunisation Focus Group taking place on day two (8th many hundreds of your fellow delegates from around the December) from 10:15 – 14:15 tasked with overcoming vaccination hesitancy across world. Please make the most of what promises to be our Europe. Delegates are welcome to attend. most inspiring scientific programme to-date that combines applied medicine and interactive learning to improve the n Every session has 3 clear learning objectives, instantly deployable in your every-day way you practice. practice-allowing you to know what you will learn from each session before you decide to attend. G.Syrogiannopoulos 2017 Scientific Program Coordinator n Over 150 accepted abstracts, 100 poster displays and 9 hours of new science and Professor and Chairman of Pediatrics at the School research in 5 oral presentations sections taking place across first two days of the of Medicine, University of Thessaly conference. CONFERENCE PROGRAMME 2017 programme THURSday, 7 December 2017 5 9th EDITION

PROGRAMME

DAY 1: THURSDAY, 7 DECEMBER 2017 | MORNING SESSIONS

08:00 REGISTRATION DESK OPENS

08:30 09:30 COFFEE START (Foyer Mancini 3A)

09:30 10:45 OPENING CEREMONY & PLENARY ADDRESSES Conference Chairs´ Welcome: TERENCE STEPHENSON JO INCHLEY JOAN-CARLES SURIS Nuffield Professor of Child Health, Institute of Child HBSC International Coordinator, Institute of Social and Preventive Medicine and Department Health, UCL, Chair General Medical Council (UK) 2015- University of St Andrews School of Pediatrics Lausanne University Hospital, 2018, Former Chair, UK Academy of Medical Royal of Medicine, SWITZERLAND Colleges 2012-2014, Past President, Royal College UNITED KINGDOM of Paediatrics and Child Health 2009-2012, UNITED KINGDOM

2017 Plenary Addresses from the Co-Chairs • Obesity and Physical Activity: The Next Generation JO INCHLEY HBSC International Coordinator, University of St Andrews School of Medicine, UNITED KINGDOM • Sex Drugs and a Bit of Acne: Today's Adolescents JOAN-CARLES SURIS Institute of Social and Preventive Medicine and Department of Pediatrics Lausanne University Hospital, SWITZERLAND Scientific Programme Scientific 11:00 - 13:00 | Mancini 2 Hall 11:00 - 13:00 | Mancini 1 Hall 11:00 - 13:00 | Mancini 3B Hall 11:00 - 13:00 | Wien Room 11:00 - 13:00 | Turin PE1: PEDIATRICS AD1: ADOLESCENT MEDICINE INF1: INFOCUS SESSION NE1: NEONATOLOGY & Room Also available through EIP Online Also available through EIP Online EARLY LIFE PEDIATRICS Section on Section on INFLUENCE OF Section on OP1: ORAL GENERAL PEDIATRICS ADOLESCENT MICROBIOTA ON ASPECTS NEONATOLOGY PRESENTATIONS WELLBEING OF CHILD HEALTH 3 Sessions 3 Sessions 3 Sessions 3 Sessions 12 Presentations Presentations - Q&A Session Presentations - Q&A Session Presentations - Q&A Session Presentations - Q&A Session Q&A Session Moderator: ANDREW RIORDAN Moderator: CURT HAGQUIST Chair: SIMON KROLL Moderator: ROY K. PHILIP Moderator: JUDIT VILLOSLADA • General Practice - Febrile • Teen Health Week: • Part A - Gastrointestinal • Neonatal Outbreaks: General Pediatrics Children in Primary Care - Advocating for Young Microbiota in Neonates and Approaching with Evidence Consultant, Hopital de The Latest Practical Advice People as a Clinician Necrotizing Enterocolitis and Effectiveness l’Enfance, Lausanne, for Frontline Paediatricians LAURA OFFUTT SIMON KROLL ROY K. PHILIP Centre Hospitalier GIJS ELSHOUT Founder and Creator Teen Health Professor of Paediatrics and Consultant Paediatrician and Universitaire Vaudoise, General Practitioner, Assistant Week, USA Molecular Infectious Diseases, Neonatologist, Adjunct Clinical SWITZERLAND Professor, Department of General Imperial College and St Mary’s Professor of Neonatology, University Practice. Erasmus MC University • Adolescents Well-being in Hospital, UNITED KINGDOM Maternity Hospital Limerick & GEMS, Medical Center Rotterdam, THE Romania: Linking Data and University of Limerick, IRELAND NETHERLANDS Practice • Part B - Evolution of ADRIANA BABAN Respiratory Tract • Diagnosing Neonatal • Pyrexia of Unknown Origin Principal Investigator HBSC, Microbiota and its Relation Respiratory Distress ANDREW RIORDAN Department of Psychology, to Respiratory Health in Syndrome (RDS): An Update for Consultant in Paediatric Infectious Babes-Bolyai University, Children Pediatricians Diseases and Immunology at Alder ROMANIA DEBBY BOGAERT Hey Children’s Hospital, UNITED FRANCESCO RAIMONDI Professor of Paediatric Infectious Chief, Division of Neonatology, KINGDOM • Consequences for Diseases and Honorary Everyday Life of Mental Section of Pediatrics Dept of • Functional Abdominal Pain Consultant in paediatric Translational Medical Sciences, Health Problems Among infectious diseases, Center Università "Federico II" di Napoli, MARK BEATTIE Adolescents for Inflammation Research, ITALY Professor, Consultant Paediatric University of Edinburgh, UNITED Gastroenterologist, University CURT HAGQUIST KINGDOM Professor of Public Health, • Integrative Prenatal Diagnostic Hospital Southampton, UNITED and Postnatal Management KINGDOM Director and founder of the • Part C - Modulating the Gut Centre for Research on Child for Congenital Malformation - and Adolescent Mental Health Microbiome in Early Life – Vesico-ureteral Reflux (CFBUPH) at Karlstad University, Impact on Future Health? SWEDEN SEBASTIAN IONESCU STEPHEN ALLEN Profesor of Pediatric Surgery, Clinica Professor of Paediatrics de Chirurgie Pediatrică, Spitalul and Honorary Consultant Clinic de Urgenţă pentru Copii Maria Paediatrician, Liverpool School Sklodowska Curie, ROMANIA of Tropical Medicine, UNITED KINGDOM

13:00 - 14:00 LUNCH BREAK (Mancini 3A and Foyer)

13:00 - 14:00 POSTER VIEWINGS (Lunchtime Viewing Groups & Guided Tours) - Hall: Mancini 3A - Group 1, 2 , 3 - JOAN-CARLES SURIS, JUDIT VILLOSLADA, CHRISTINA AKRE CONFERENCE PROGRAMME 2017 programme THURSday, 7 December 2017 6 9th EDITION

DAY 1: THURSDAY, 7 DECEMBER 2017 | AFTERNOON SESSIONS 14:00 - 16:00 | Mancini 2 Hall 14:00 - 16:00 | Mancini 1 Hall 14:00 - 14:40 | Mancini 3B 14:00 - 14:40 | Wien Room 14:00 - 16:00 | Turin Room PE2: PEDIATRICS PE3: PEDIATRICS WS1: WORKSHOP WS2: WORKSHOP Also available through Also available through EIP Online EIP Online Section on Section on NEPHROTIC SYNDROME CHILD & ADOLESCENT OP2: ORAL ENDOCRINOLOGY & CHILDHOOD OBESITY MENTAL HEALTH PRESENTATIONS GROWTH 4 Sessions 4 Sessions 1 Tutor 1 Tutor 13 Presentations Presentations - Q&A Session Presentations - Q&A Session Briefing with Q&A Audience Response Session Q&A Session Moderator: TIM CHEETHAM EAROC Section - Obesity: A Topic • Management of Childhood • Diagnosis and Management Moderator: for the Paediatrician? A Multisystem Nephrotic Syndrome of Autism & ADHD JOAN-CARLES SURIS • Thyroid Disorders in the Approach to Tackling Childhood NICK WEBB MICHAEL FITZGERALD Young – What to do? Institute of Social and Obesity Honorary Professor of Paediatric Professor of Child and Adolescent Preventive Medicine and TIM CHEETHAM Nephrology, University of Psychiatry, IRELAND Chair: KURT WIDHALM Department of Pediatrics University Reader and Consultant Manchester and Consultant Lausanne University Hospital, Paediatric Endocrinologist, Paediatric Nephrologist, Royal SWITZERLAND Newcastle University, Newcastle • Policies, Politics and Manchester Children’s Hospital, upon Tyne Hospitals NHS Prevention of Pediatric Manchester, UNITED KINGDOM Foundation Trust, UNITED Obesity in Denmark KINGDOM INGE LISSAU Associate Professor, Senior 14:40 - 15:20 | Mancini 3B 14:40 - 15:20 | Wien Room Scientific Programme • Growth - Normal and Research Scientist at Clinical WS3: WORKSHOP WS4: WORKSHOP Abnormal Research Unit, Copenhagen ALAN D. ROGOL University Hospital, Hvidovre, Professor Emeritus, Pediatrics DENMARK and Department of VACCINE HESITANCY RESPIRATORY and Pharmacology, University of Child Health, Skane University Virginia, USA Hospital, Malmö, SWEDEN 1 Tutor 1 Tutor Audience Response Session Audience Response Session • Congenital Combined • Family/Systemic Therapy in Pituitary Hormone Treating Childhood Obesity • Overcoming Vaccine • Pediatric Bronchoscopy - Deficiency Hesitancy Indications for Rigid and CARL-ERIC FLODMARK Flexible Bronchoscopy JERZY B. STARZYK Medical Officer at Swedish ROY K. PHILIP Professor, Head of the Department National Board of Health and Consultant Paediatrician and SUSANNE LAU of Pediatric and Adolescent Welfare and Associated Professor Neonatologist, Adjunct Clinical Prof. Charité-Universitätsmedizin Endocrinology, Jagiellonian at Lund University, Malmö, Professor of Neonatology, Berlin, Department of Pediatric University, Medical College, SWEDEN University Maternity Hospital Pneumonology and Immunology, Faculty of Medicine, Institute of Limerick & GEMS, University of GERMANY Pediatrics, University Children’s • Sedentary Behaviours in Limerick, IRELAND Hospital in Krakow, POLAND Children LUIS MORENO AZNAR 15:20-16:00 | Mancini 3B Hall 15:20 - 16:00 | Wien Room • Translational Research in Full Professor at the University of Pediatric Growth Disorders Zaragoza, President of the Spanish PD1: PROFESSIONAL WS5: WORKSHOP FARASAT ZAMAN Nutrition Society, SPAIN DEVELOPMENT Assistant Professor, Department Also available through of Women's and Children's Health, • Early-life Nutrition and EIP Online Karolinska Institutet, SWEDEN Future Health: Will They be Giants? PUBLISHING WORKSHOP CYSTINOSIS ANGELO PIETROBELLI Professor of Pediatric and GETTING RESEARCH Nutrition at Pediatric Unit of PUBLISHED 1 Tutor Verona University Medical School, Audience Response Session Adjunct Associate Professor at 1 Tutor Pennington Biomedical Research Interactive Workshop • Spotting the Early Signs of Center Baton Rouge LA – USA, Cystinosis Associate Editor International MARK BEATTIE Journal of Obesity, Senior Editor in Chief, Archives of Disease NICK WEBB Physician at Pediatric Clinic, ITALY in Childhood, BMJ Publishing Honorary Professor of Paediatric group, UNITED KINGDOM Nephrology, University of Manchester and Consultant Paediatric Nephrologist, Royal Manchester Children’s Hospital, Manchester, UNITED KINGDOM

16:00 - 16:30 COFFEE BREAK (Foyer & Mancini 3A) CONFERENCE PROGRAMME 2017 programme THURSday, 7 December 2017 7 9th EDITION

DAY 1: THURSDAY, 7 DECEMBER 2017 | AFTERNOON SESSIONS 16:30 - 18:30 | Mancini 2 Hall 16:30 - 18:30 | Mancini 1 Hall 16:30-17:30 | Mancini 3B Hall 16:30 - 18:00 | Wien Room 16:30 - 18:30 | Turin PE4: PEDIATRICS AD2: ADOLESCENT MEDICINE WS6: WORKSHOP WS7: WORKSHOP Room Also available through EIP Online OP3: ORAL PRESENTATIONS Section on Section on COMMUNITY MANAGEMENT OF 12 Presentations - GASTROENTEROLOGY ADOLESCENT HEALTH PEDIATRICS SPORTS INJURIES Q&A Session COMMUNICATION Moderator: 4 Sessions 3 Sessions 1 Tutor 2 Tutors CHRISTINA AKRE Presentations - Q&A Session Presentations - Q&A Session Hands on Session • The Goshen Project: A Research manager Lausanne University Moderator: KURT WIDHALM Moderator: GERALD HUMPHRIS Model for Implementing Moderator: BOB SALLIS Hospital, Institute Comprehensive of Social and • Genetics and treatment of • The Emotional Cues and Community Pediatrics • Essentials of the Knee Preventive Medicine, lipoprotein disorders - PART 1 - Concerns Expressed by Exam BASIL PORTER SWITZERLAND Familial hypercholesterolemia Oncology Paediatric Patients Emeritus Professor, Faculty of BOB SALLIS – state of the art and the 17 Different Ways that Health Sciences, Ben Gurion Clinical Professor of Family KURT WIDHALM Health Providers Respond University of the Negev, Medicine, UC Riverside School President of the Austrian Academic GERALD HUMPHRIS Beersheva, ISRAEL of Medicine, USA, Co-Director, Institute for Clinical Nutrition, Chair in Health Psychology at Sports Medicine Fellowship, Professor (Em.) at the Medical University of St Andrews, Director of Kaiser Permanente, Chair, University Vienna, AUSTRIA MSc Health Psychology course and Exercise is Medicine, USA Co Director of the WHO Collaborating • Genetics and Treatment of Centre in International Child and • Essentials of sports- related back pain in Lipoprotein Disorders - PART 2 Adolescent Health, UNITED KINGDOM 17:30-18:30 | Mancini 3B - Novel exciting treatments of children severe forms • Health Literacy Assessment in WS8: WORKSHOP COURTNEY KIPPS CLAUDIA STEFANUTTI, MD, PhD 13- to 17-year old Austrians: Principal Clinical Teaching Fellow Professor, Head of Extracorporeal Results and Measurement and Consultant in Sport and Therapeutic Techniques Unit, Lipid Problems BREASTFEEDING Exercise Medicine The Institute Clinic and Atherosclerosis Prevention of Sport, Exercise & Health UCL, ROSEMARIE FELDER-PUIG UNITED KINGDOM Centre, Regional Centre for Rare Principal Investigator, Institute 1 Tutor Diseases Department of Molecular for Health Promotion and Disease Audience Response Session Medicine, ‘Sapienza’ University of Prevention, HBSC AUSTRIA Rome and ‘Umberto I’ Hospital, ITALY • Teaching Mothers How to • Seizing Golden Communication Breastfeed • Epidemiology, Diagnosis and Opportunities in Pediatric

Tutor: IOANNA GRIVEA, Programme Scientific Management of Inflammatory Consultations Associate Professor of Pediatrics Bowel Disease - Recent TORUN MARIE VATNE and Neonatology at the University Advances Frambu Resource Center for Rare of Thessaly, GREECE MARK BEATTIE Disorders, NORWAY Professor, Consultant Paediatric Gastroenterologist, University Hospital Southampton, UNITED KINGDOM • Microbiome and Feacal Transplant AZIZ KOLEILAT Associate Professor, Makassed University General hospital Gastroenterology & Asthma, Vice General Secretary (PASPGHAN) foreign affairs, Pan Arab Society Pediatric Gastroenterology,Hepatology & Nutrition, LEBANON

18:30 WELCOME RECEPTION - Foyer (Outside Mancini Halls 1 & 2) - All Delegates Invited CONFERENCE PROGRAMME 2017 programme friday, 8 December 2017 8 9th EDITION

DAY 2: FRIDAY, 8 DECEMBER 2017 | MORNING SESSIONS

08:00 - 09:00 COFFEE START (Foyer & Mancini 3A) 09:00 - 11:00 | Mancini 2 Hall 09:00 - 11:00 | Mancini 1 Hall 09:00 - 11:00 | Mancini 3B Hall 09:00 - 11:00 | Turin Room PE5: PEDIATRICS PE6: PEDIATRICS AD3: ADOLESCENT 10:15 - 14:15 | Wien Room PD2: PROFESSIONAL MEDICINE DEVELOPMENT 1 Available through EIP Online FG1: HEALTH POLICY & Section on RARE DISEASES Section on ORAL Section on ADVOCACY LEADERSHIP HEALTH TRANSITION TO ADULT & TEAM 4 Sessions CARE DEVELOPMENT Presentations - Q&A Session 3 Sessions 3 Sessions LIFE COURSE 2 Tutors Moderator: UMA RAMASWAMI Presentations - Q&A Session Presentations - Q&A Session IMMUNISATION Interactive Workshop Moderator: RICHARD WIDMER Moderator: JOAN-CARLES SURIS Focus Group Meeting • Transforming Rarity into Knowledge to Care for and Cure Children with Rare Diseases • Important "First Aid" • The MOCHA Project - • 2nd Life Course ALISON JOHNS FRANCESC PALAU for Oro-Facial Injuries in Appraising the Differing Immunisation Focus Chief Executive of the Director of the Institute for Pediatric Rare Diseases (IPER) Children Models of Child Health Group - Open to All Leadership Foundation and Head of the Genetics Department, Sant Joan de Déu that are Used Across Coffee and Lunch Served for Higher Education, Children's Hospital. CSIC Research Professor and Visiting RICHARD WIDMER UNITED KINGDOM Head of Department & Senior Europe During the Meeting Professor Pediatrics, University of Barcelona, SPAIN DOUG PARKIN Staff Specialist, Paediatric MITCH BLAIR Dentistry, Children’s Hospital at Co-Chairs: Programme Director, • Emergency Management, Inherited Professor of Paediatrics Leadership Foundation Westmead , Sydney Childern’s and Child Public Health; TERENCE STEPHENSON

Scientific Programme Metabolic Disorders Hospital Network. AUSTRALIA Nuffield Professor of Child for Higher Education, Principal Investigator, UNITED UNITED KINGDOM UMA RAMASWAMI KINGDOM Health, Institute of Child Health, Consultant in Inherited Metabolic Disorders, • The Front End of UCL, Chair General Medical Lysosomal Disorders Unit, Royal Free Hospital, Paediatrics: Oral Health • The Transition for Council (UK) 2015-2018, London, UNITED KINGDOM and Nutrition Endocrine Complex Former Chair, UK Academy of Medical Royal Colleges 2012- • Ehlers Danlos Syndrome - The New COLIN MICHIE Diseases 2014, Past President, Royal 2017 Classification. A Clinical Guide for Consultant Paediatrician, LUISA DESANCTIS College of Paediatrics and Child Paediatricians Royal National Orthopaedics University of Turin, ITALY Health 2009-2012, UNITED Hospitals, Imperial and KINGDOM GLENDA SOBEY University College, UNITED • Six Core Elements of Head of Ehlers-Danlos Syndrome National Diagnostic KINGDOM DAPHNE HOLT Service, Sheffield Children’s Hospital, Sheffield, Health Care Transition: Acting Chair Coalition for UNITED KINGDOM • Oral Health and the A Quality Improvement Life-course Immunisation, Implications for Systemic Approach for Primary Former Vice President, • Vitamin-Dependent Encephalopathies - Health and Specialty Care Confederation of Meningitis Cerebral Folate Deficiency - An Update Organisations, FRANCE RICHARD WIDMER PEGGY McMANUS ROBERT STEINFELD Head of Department & Senior Got Transition and The DAVID SALISBURY National Alliance to Advance Associate Fellow, Centre on Coordinator of expert centre - Clinical expert Staff Specialist, Paediatric Dentistry, Children’s Hospital at Adolescent Health, USA Global Health Security, Royal - Responsible for diagnostic of lysosomal and Institute for International neurometabolic disorders Centre for rare pediatric Westmead , Sydney Childern’s Hospital Network. AUSTRALIA Affairs, Chatham House, neurological diseases (GoRare) University Medical UNITED KINGDOM Centre Göttingen, GERMANY

11:00 - 11:30 COFFEE BREAK (Mancini 3A and Foyer) 11:30 - 13:30 | Mancini 2 Hall 11:30 - 13:30 | Mancini 1 Hall 11:30 - 13:30 | Mancini 3B Hall • POLICY 11:30 - 13:30 | Turin Room PE7: PEDIATRICS PE8: PEDIATRICS PE9: PEDIATRICS Setting the Scene - Overview of Vaccines Also available through EIP Online Also available through EIP Online Policies, Changes Made Section on DIET & Section on NEUROLOGY Section on and Steps Taken in the OP4: ORAL ALLERGIES DERMATOLOGY last 12 months PRESENTATIONS • PLANNED ACTIONS 4 Sessions 4 Sessions 2 Tutors Introducing the 12 Presentations - Presentations - Q&A Session Presentations - Q&A Session Audience Response Session Coalition for Life Course Q&A Session Moderator: LEANNE GOH Moderator: BOB SALLIS Immunisation (CLCI) • Practical Advice for Children • Management of Headaches INTERACTIVE PEDIATRIC • Working Group A on Moderator: with Cow’s Milk Allergy KENNETH J. MACK DERMATOLOGY CASES Advocacy CHRISTINA AKRE YVAN VANDENPLAS Professor, President Child Neurology Society, Mayo Improving the Advocacy Research manager Professor, Head of Department Clinic, Child and Adolescent Neurology, USA • Test Yourself in Pediatric of all Healthcare Lausanne University of Paediatrics, Universitair Dermatology. An Professionals Hospital, Institute of Ziekenhuis Brussel, BELGIUM • What is Concussion and How to Interactive Case-oriented Social and Preventive Manage it? Workshop - PART 1 • Working Group B on Medicine, SWITZERLAND • Elimination Diets as a COURTNEY KIPPS DIRK VAN GYSEL Vaccine Hesitancy Diagnostic Tool Principal Clinical Teaching Fellow and Head of the Department of Overcoming Vaccine SOPHIA KALLIS Consultant in Sport and Exercise Medicine Pediatrics, O.L Vrouw Hospital Hesitancy Specialist Paediatric Allergy Dietitian The Institute of Sport, Exercise & Health UCL, Aalst. Board member and at University College London UNITED KINGDOM former Treasurer of the ESPD, • Working Group C on Hospital, UNITED KINGDOM BELGIUM a Europe-wide Life • Update on Concussions: Why the Hysteria Course Immunisation • Interactive Case Studies in Around the Injury May be a Threat to Health • Test Yourself in Strategy Paediatric Allergy BOB SALLIS Pediatric Dermatology. A Europe-wide life course PENNY SALT Clinical Professor of Family Medicine, UC Riverside An Interactive Case- immunisation strategy Consultant Paediatrician and School of Medicine, USA, Co-Director, Sports oriented Workshop - Allergist, University College London Medicine Fellowship, Kaiser Permanente, Chair, PART 2 • Conclusions and Close Hospital, UNITED KINGDOM Exercise is Medicine, USA BARBARA KUNZ Specialist Dermatologist, • Anaphylaxis • Different Therapeutic Approaches in Direction of Paediatric LEANNE GOH the Treatment of Cerebral Palsy dermatology, Dermatologikum Consultant in General Paediatrics SVETISLAV POLOVINA Hamburg, Board member and Paediatric Allergy University Specialist Physical Medicine and Rehabilitation, of the European Society College London Hospital, UNITED Polyclinic for Physical Medicine and of Pediatric Dermatology KINGDOM Rehabilitation, CROATIA (ESPD), GERMANY CONFERENCE PROGRAMME 2017 programme friday, 8 December 2017 9 9th EDITION

DAY 2: FRIDAY, 8 DECEMBER 2017 | AFTERNOON SESSIONS

13:30 - 14:30 LUNCH BREAK | POSTER VIEWINGS 2 (Lunchtime Viewing Groups & Guided Tours) - Hall: Mancini 3A - Group 1, 2 , 3 - JOAN-CARLES SURIS, JUDIT VILLOSLADA, CHRISTINA AKRE

13:30 - 14:30 PRACTICAL HOW TO... DEMONSTRATION SESSIONS (delivered by the Conference Faculty) 15 minutes each - Hall: Mancini 3A - Seating for 25 PENNY SALT, SOPHIA KALLIS, LEANNE GOH, Consultant Paediatrician and Allergist, Specialist Paediatric Allergy Dietitian at Consultant in General Paediatrics and Paediatric University College London Hospital, University College London Hospital, Allergy University College London Hospital, UNITED KINGDOM UNITED KINGDOM UNITED KINGDOM

• Basic eczema skin care • Milk alternative • Adrenaline autoinjectors › Avoiding triggers › Review of hypoallergenic formulas and › Educating patients on how to recognise anaphylaxis › Bathing the child with eczema dairy free milks › Adrenaline autoinjector technique › Effective application of emollients › Practical tips for the successful introduction › Written allergy action plans of milk alternatives › Creative use of milk alternatives in cooking

14:30 - 16:30 | Mancini 2 14:30 - 16:30 | Mancini 1 Hall 14:30 - 16:30 | Mancini 3B Hall 14:30 - 15:10 | Wien Room 14:30 - 15:30 | Turin Room Hall NE2: NEONATOLOGY SΕS1: SPOT THE EARLY SIGNS BR1: BRIEFING PD3: PROFESSIONAL PE10: PEDIATRICS DEVELOPMENT Also available through EIP Online Section on Section on PART OF THE SPOT THE EARLY PREBIOTICS & WRITING SCIENTIFIC INFECTIOUS DISEASES NEONATOLOGY SIGNS WEBINAR SERIES PROBIOTICS PAPERS 4 Sessions 2 Sessions 4 Tutors Presentation - Q&A Session 1 Tutors Presentations - Q&A Presentations - Q&A Session Training Course Interactive Workshop • Prebiotics and Session IMTI CHOONARA Moderator: FRANCESCO Moderator: UMA RAMASWAMI Probiotics - An Update Editor in Chief of BMJ Moderator: ANDREW RAIMONDI for the General Paediatrics Open, RIORDAN SES - Metabolic Disorders Training 1 Paediatrician BMJ Publishers and RCPCH,

YVAN VANDENPLAS London, UNITED KINGDOM Programme Scientific • Should We Use • Normal Motor • Gaucher Disease: Spot the Early Professor, Head of Antipyretics Before Development in the First Signs in the Pediatric Population Department of Paediatrics, Vaccination? Year of Life GIOVANNI CIANA Universitair Ziekenhuis ANDREW RIORDAN ANDREA POLOVINA Regional Coordinating Centre for Brussel, BELGIUM Consultant in Paediatric Specialist Physical Medicine Rare Diseases, Azienda Ospedaliero- Infectious Diseases and and Rehabilitation, Polyclinic Universitaria”S.Maria della Misericordia”, Immunology at Alder Hey for Physical Medicine and Udine, ITALY Children’s Hospital, UNITED Rehabilitation, CROATIA 15:10 - 15:50 | Wien Room KINGDOM SES - Metabolic Disorders Training 2 WS9: WORKSHOP • Neonatal • The Impact of Routine Hyperbilirubinemia in • Fabry Disease - Do We Need Better 15:30 - 16:30 | Turin Room National Immunization 2017: An Update for Biomarkers in Lysosomal Storage PD4: PROFESSIONAL Programmes on Disorders? CHILD & ADOLESCENT Pediatric HCPs MENTAL HEALTH DEVELOPMENT Antibiotics Throughout FRANCESCO RAIMONDI PATRICIO AGUIAR Europe Chief, Division of Neonatology, Inherited Metabolic Disorders Adult Clinic, 1 Tutor SOCIAL MEDIA: CATHERINE WEIL-OLIVIER Section of Pediatrics Dept Reference Center in Inherited Metabolic Presentation - Q&A Session KNOWLEDGE Honorary Professor of of Translational Medical Disorders. Centro Hospitalar Lisboa TRANSLATION IN THE Pediatrics and Independent Sciences, Università Norte (Hospital de Santa Maria), Lisbon, PORTUGAL • Early Intervention for 21ST CENTURY Expert, FRANCE "Federico II" di Napoli, ITALY Eating Disorders 1 Tutor • Have our expectations SES - Metabolic Disorders Training 3 DASHA NICHOLLS Consultant Child and Workshop been attained by • Spotting the Signs of Lysosomal pneumococcal Adolescent Psychiatrist, DAMIAN ROLAND Storage Diseases in Order to Make Great Ormond Street Hospital, Consultant and Honorary conjugate vaccines? an Early Diagnosis UNITED KINGDOM Associate Professor in GEORGE FRANCOIS EYSKENS, Professor, CEMA- Paediatric Emergency SYROGIANNOPOULOS Centrum Erfelijke Metabole Aandoeningen, 15:50 -16:30 | Wien Room Medicine, University of Professor and Chairman of BELGIUM Leicester and Leicester Paediatrics at the University WS10: WORKSHOP Hospitals, UNITED KINGDOM of Thessaly, School of SES - Metabolic Disorders Training 4 Medicine in Larissa, GREECE HEPATITIS C • Spot the Early Signs of • European Attitudes Mucopolysaccharidoses - One 1 Tutor to Vaccination and Disease with Many Faces Briefing with Q&A Meningitis - A Combined Approach SUSANNE KIRCHER LSD metabolism screening and genetic • Treatment of Hepatitis ELENA MOYA counseling, Medizinische Universität Wien, C Virus Infection in Co-ordinator for Europe and Zentrum für Pathobiochemie und Genetik, Children Africa - COMO Institut für Medizinische Chemie und GIUSEPPE INDOLFI CATHERINE WEIL-OLIVIER Pathobiochemie, Institut für Medizinische Consultant Paediatric Honorary Professor of Genetik, Wien, AUSTRIA and Liver Unit Azienda Pediatrics and Independent Ospedaliero-Universitaria Expert, FRANCE Meyer, Florence, ITALY

16:30 - 17:00 COFFEE BREAK (Foyer & Mancini 3A) CONFERENCE PROGRAMME 2017 programme friday, 8 December 2017 10 9th EDITION

DAY 2: FRIDAY, 8 DECEMBER 2017 | AFTERNOON SESSIONS 17:00 - 18:30 | Mancini 2 Hall 17:00 - 17:45 | Mancini 1 Hall 17:00 - 18:30 | Mancini 3B Hall 17:00 - 18:00 | Wien Room 17:00-18:30 | Turin Room PE11: PEDIATRICS BR2: BRIEFING PD5: PROFESSIONAL SES2: SPOT THE EARLY OP5: ORAL Also available through EIP Online DEVELOPMENT SIGNS PRESENTATIONS Section on RESPIRATORY PRESENTATION SPOT THE EARLY 10 Presentations - Q&A ENDOCRINOLOGY SKILLS FOR SIGNS Session Presentation - Q&A Session HEALTHCARE Moderator: 3 Sessions PROFESSIONALS 1 Tutor JOAN-CARLES SURIS Presentations - Q&A Session • Better Management of Paediatric Training Course Airway Disease: Lessons from 2 Tutors Institute of Social and Moderator: TIM CHEETHAM the Progress in Cystic Fibrosis Interactive Workshop Moderator: UMA Preventive Medicine and ANDREW BUSH RAMASWAMI Department of Pediatrics • Cranial Diabetes Insipidus – ALISON JOHNS Lausanne University Professor of Paediatrics and Head of Chief Executive of the Lessons Learned Section (Paediatrics), Imperial College, Hospital, SWITZERLAND Leadership Foundation for SES - Metabolic Disorders TIM CHEETHAM Professor of Paediatric Respirology, Higher Education, UNITED University Reader and Consultant National Heart and Lung Institute, KINGDOM Training 5 UNITED KINGDOM Paediatric Endocrinologist, Newcastle DOUG PARKIN • Case Studies in University, Newcastle upon Tyne Hospitals Programme Director, NHS Foundation Trust, UNITED KINGDOM Clinical Genetics: Leadership Foundation for Hints and Pitfalls Higher Education, UNITED for Undiagnosed • Abnormal Puberty as a First 17:45 - 18:30 | Mancini 1 Hall KINGDOM Symptom of Disorders/Differences Lysosomal Storage of Sex Development (DSD) BR3: BRIEFING Disorders

Scientific Programme MARIA SZARRAS-CZAPNIK PRIMARY VASILICA PLAIASU Consultant Endocrinologist, The Children’s Clinical Geneticist, Memorial Health Institute, Warsaw, IMMUNODEFICIENCIES Regional Center of Medical POLAND Genetics Bucharest, INSMC Presentation - Q&A Session Alessandrescu-Rusescu, • Side Effects of Glucocorticoids Pediatrics Department, with an Emphasis on Topical • How to Recognise Primary Bucharest, ROMANIA Administration Immunodeficiencies ALAN D. ROGOL JUTTE VAN DER WERFF TEN BOSCH Professor Emeritus, Pediatrics and Professor of Pediatric Hematology, Pharmacology, University of Virginia, USA Oncology and Immunology, Paola Childrens Hospital, Antwerpen, BELGIUM

18:30 CLOSE OF DAY 2 CONFERENCE PROGRAMME 2017 programme Saturday, 9 December 2017 11 9th EDITION

DAY 3: SATURDAY, 9 DECEMBER 2017 | MORNING SESSIONS

08:30 - 09:30 COFFEE START (Foyer & Mancini 3A) 09:00-11:30 | Mancini 3B Hall MC1: MASTERCLASS 09:30-11:30 | Mancini 2 Hall 09:30-11:30 | Mancini 1 Hall 09:30-11:30 | Wien Room 09:30-11:00 | Turin Room PE12: PEDIATRICS AD4: ADOLESCENT PD6: PROFESSIONAL PD7: PROFESSIONAL Also available through EIP Online MEDICINE DEVELOPMENT DEVELOPMENT Section on Section on NEONATOLOGY LEADING CHANGE PROFESSIONAL CLINICAL PRACTICE IMPROVING FAMILY IN A COMPLEX DEVELOPMENT CVs, HEALTH 2 Tutors ENVIRONMENT GRANTS & PAPERS 3 Sessions Audience Response Session Presentations - Q&A Session 2 Sessions - Coffee served in room from 2 Tutors 1 Tutor Presentations - Q&A Session Interactive Workshop Audience Response Session Moderator: TERENCE STEPHENSON 10:00-10:30 • Essentials of Invasive and • Do we use Medicines Rationally? • Adolescent Mental Non-invasive Ventilation • Leading Change in a • Academic Survival: What Should be Considered When Health: Supporting Young in Newborns Complex Environment How to Write Your CV, Prescribing? People with Caregiving ROLAND HENTSCHEL ALISON JOHNS Grant Applications and IMTI CHOONARA Responsibilities and Their Professor, Head of Division Chief Executive of the Papers Emeritus Professor in Child Health, Families Neonatology/Pediatric Intensive Leadership Foundation for ANDREW BUSH Academic Division of Child Health AAGJE IEVEN Care at Department Pediatrics, Higher Education, UNITED Professor of Paediatrics and (), The Medical Secretary General, EUFAMI, University Hospital Freiburg, KINGDOM Head of Section (Paediatrics), School, Derbyshire Children’s Hospital, BELGIUM GERMANY DOUG PARKIN Imperial College, UNITED KINGDOM TORSTEN UHLIG Programme Director, Professor of Paediatric JOY LADURNER Respirology, National Heart HPE AUSTRIA Head of Department of Leadership Foundation for • Decision Making in Paediatric Pediatrics, Klinikum Rosenheim Higher Education, UNITED and Lung Institute, UNITED Care: Are we Training Staff • The Family as a & Lecturer in Pediatrics at LMU KINGDOM KINGDOM Effectively? Protective Health University Munich, GERMANY DAMIAN ROLAND and Paracelsus University Asset for Adolescents’ Salzburg, AUSTRIA Consultant and Honorary Associate Development: Insights Professor in Paediatric Emergency from the HBSC Study Medicine, University of Leicester and PART 1 Essentials of CPAP and Leicester Hospitals, UNITED KINGDOM ELLEN KLEMERA High flow-nasal cannula. Senior Research Fellow in PART 2 Essentials of invasive • Paediatric High Dependency Care Adolescent, Child and Family Programme Scientific (Paediatric Critical Care Levels I & Health Team, University of ventilation (incl. HFOV). II): Role and Value Globally Hertfordshire, HBSC England, PART 3 Essentials of non- UNITED KINGDOM ROY K. PHILIP invasive ventilation. Consultant Paediatrician and PART 4 Essentials of surfactant Neonatologist, Adjunct Clinical Professor treatment and nitric oxide (NO). of Neonatology, University Maternity Hospital Limerick & GEMS, University of Limerick, IRELAND

11:30 - 12:00

PLENARY CLOSING LECTURE (Mancini 2 Hall) • Five Papers Which Changed My Practice TERENCE STEPHENSON Nuffield Professor of Child Health, Institute of Child Health, UCL, Chair General Medical Council (UK) 2015-2018, Former Chair, UK Academy of Medical Royal Colleges 2012-2014, Past President, Royal College of Paediatrics and Child Health 2009-2012, UNITED KINGDOM

12:00 - 12:30

CONFERENCE CLOSING REMARKS (Mancini 2 Hall) CONFERENCE CHAIRS: TERENCE STEPHENSON, JOAN-CARLES SURIS, JO INCHLEY CONFERENCE PROGRAMME 2017 Conference General Information 12 9th EDITION

CONFERENCE GENERAL INFORMATION INFORMATION FOR SPEAKERS

Official Language Certificate of Attendance Speaker Ready Room

The official language of the Conference All registered delegates are entitled to The Speakers’ Ready Room (SRR) is is English. a Certificate of Attendance. Certificates the Laura Mancini Room and is located can be collected from the Conference on the Ground Floor of the hotel to the Badges & Conference Material Secretariat from the afternoon of 8 left of the lobby after entering the venue. December. The certificates will be It will be operating from 20:00 - 21:30 on Name Badges and Conference provided on site upon completion of a the 6th December, from 08:00 to 18:00 Material will be provided on-site to all Conference feedback form. on the 7th December and 8th December. registered delegates at the Conference The SRR will not be operating on the Registration Desks, from 07 December 9th December and speakers presenting to 09 December. Badges are to be Programme Changes on the 9th should either upload their worn at all times, for reasons of Due to circumstances beyond the control presentation in the SRR on the 6th/7th security and identification. You will not of the Conference Organisers, last or 8th or bring it to the room they are be permitted to enter any room without minute changes to the programme may presenting in on the 9th. your badge. be unavoidable. All information included in this programme is accurate as at the Speakers are kindly requested to day of printing, 17 November 2017. Abstracts book part of the final hand in their presentation (USB-key, programme CD-ROM, DVD) at least two (2) hours Abstracts of oral and poster before their scheduled presentation presentations will be distributed to all time. If your presentation is scheduled registered delegates. Abstracts will early in the morning, you are kindly also be published in the online library requested to hand in your presentation accessible through the EiP Institute’s at the Speakers’ Ready Room the day website (www.ineip.org). All accepted before. All versions of MS PowerPoint contributions for the 9th Excellence in are accepted, including Mac. If you Pediatrics Conference will be included are using embedded video clips in in the printed publications of the EIP your presentation, please remember 2017 Final Conference Program. to submit video files separately. The The abstract book (including all following audiovisual equipment will be accepted abstracts) will be published by available for all presenters: Cogent Medicine and made available on the Cogent Medicine website as well • PC as on the EIP Conference website and • Data video projector EIP Institute websites. In addition, all (PowerPoint presentations) abstracts will be uploaded and available • Laser Pointer through the Institute’s online library. • Microphones. Cogent Medicine is a multidisciplinary open access journal, publishing experimental, translational & clinical approaches in all areas of the biomedical sciences and clinical research and practice. The journal is the official publishing partner of the 9th Edition of the EIP Conference. CONFERENCE PROGRAMME 2017 oral and poster presenters 13 9th EDITION

ORAL AND POSTER PRESENTERS

Oral Presentations Poster Presentations

If you are presenting an oral podium Two poster-viewing sessions are For Posters to be exhibited, please presentation, you are kindly requested included in the conference program, note the following: to observe the following points: one for each of the first two days of the conference. 1. The necessary material for • Your presentation should last a displaying the posters will be maximum of 8 minutes. 1. If you are included in the 1st Poster available in the poster area. Viewing Session, please post on the • Speakers are kindly requested to first day of the conference from 09.00 2. Poster numbers will be displayed at hand in their presentation (USB- - 11.00 and remove / dismantle by the the top of the panels. key) at least one (1) hour before their end of the day from 17.00 - 18.00 scheduled presentation time. 3. The corresponding poster panel 2. If you are included in the 2nd Poster number for each poster presented • All versions of MS PowerPoint are Viewing Session, please post on the has been provided by the accepted, including Mac. If you are second day of the conference from Conference Organisers, along with using embedded video clips in your 09.00 - 11.00 and remove / dismantle abstract presentation guidelines. presentation, please remember to by the end of the day from 17.00 - 18.00 submit video files separately. The 4. Mounting and dismantling of posters following audiovisual equipment will If you are presenting a poster, you will be done as specified in the be available for all presenters: PC, are kindly requested to observe the information already sent to poster Data video projector (PowerPoint following points: presenters by the Conference presentations), Laser Pointer, Organisers. Microphones 1. English is the official language of the Conference. 5. Please note that posters should be • Please declare any conflicts of a maximum of 150cm high x120cm interest at the beginning of your 2. Each presenting author should be wide (portrait layout). presentation. present on the time and date of his/ her presentation in the poster area. 6. As a courtesy to other presenters, • Please speak slowly and clearly. participants are kindly requested not English is the working language of 3. You are expected to be standing in to move or remove poster numbers the Conference, but not necessarily front of your poster for the duration or change the order of the assigned the native language of the delegates. of the poster session. poster boards. 4. During the poster session, a 7. It is essential that presenters clear moderator will lead Poster Walk their poster board promptly and Presentations around all of the within the scheduled time. Material posters at that session. left on a poster board after the removal deadline will be discarded. 5. When the moderator visits your poster, you will be given 4 minutes to 8. The Conference Organisers are present the key points of your poster. not responsible for materials left behind or for any stolen or damaged materials. CONFERENCE PROGRAMME 2017 Attendee Services 14 9th EDITION

ATTENDEE SERVICES

All services are open daily and located at the Secretariat area in the entrance of the Photos, Video recordings Venue. There will be an authorised photographer Help at the Conference appointed by the Conference Organisers AT THE SECRETARIAT: Please contact the organiser’s staff at the registration area who will record all aspects of the event. during these operating times: These photographs will be uploaded • Thursday 7 December: 08:00 - 19:00 on the social media pages of the EiP Attendee Services • Friday 8 December: 08:00 - 19:00 Institute daily during the Conference. • Saturday 9 December: 08:00 - 13:00 Most Sessions will also be video IN PERSON: Find the friendly staff wearing the EIP’s badge in the halls and the recorded, which will be uploaded to exhibition area or visit the desks in the registration area located on the Ground Floor. the EiP Institute’s website after the Conference and available for viewing BY EMAIL: Send an email to [email protected] both by those who could not attend In the event of an Emergency the Conference and also those who attended and wish to review any For all emergencies at the Austria Trend Hotel Savoyen - fire, police and medical - contact the Conference Secretariat or any Co-ordinator of the Venue. Session.

Liability & Insurance There will also be opportunities to give Delegates are advised to arrange health and accident insurance before travelling interviews to the dedicated team at to the Conference. The Conference Organisers cannot accept liability for the Conference, in order to give your personal injury or loss/ damage to property and belongings of delegates during own testimonial of your Conference the Conference or their stay in Vienna. Please refrain from leaving your personal experience. Videos of these interviews belongings unattended in any Conference area. will also be uploaded on EiP Institute’s Mobile Phones website and social media pages after the Delegates are kindly requested to switch off their mobile phones during the close of the Conference. Conference sessions. Internet Αccess There is free Wi-Fi access in all areas of the Austria Trend Hotel Savoyen. Please log on to the Hotel’s guest network. Secretariat Operating Hours The Secretariat registration desks will be open for the duration of the Conference, please note opening times below: • Thursday 7 December: 08:00 - 19:00 • Friday 8 December: 08:00 - 19:00 • Saturday 9 December: 08:00 - 13:00 CONFERENCE PROGRAMME 2017 Attendee Services 15 9th EDITION

Social Media

Like Us: https://www.facebook.com/EIPinstitute/ Follow Us: https://twitter.com/EIP_Institute Link with Us: https://www.linkedin.com/groups/4440556

Lunches, Coffee and Social Events Offering a break from intensive learning during the programme Sessions, the coffee and lunch breaks also provide an excellent opportunity for meeting and networking with faculty members and peers from all over the world.

Lunch Breaks:

Thursday 7 December, 13:00 - 14:00 in Foyer and Mancini 3A Attendee Services Friday 8 December, 13:30 - 14:30 in Foyer and Mancini 3A

Coffee Starts and Coffee Breaks: Thursday 7 December, 08.30 - 09:30 in the Foyer and Hall: Mancini 3A Thursday 7 December, 16:00 - 16:30 in the Foyer and Hall: Mancini 3A Friday 8 December, 08:00 - 09:00 in the Foyer and Hall: Mancini 3A Friday 8 December, 11:00 - 11:30 in the Foyer and Hall: Mancini 3A Friday 8 December, 16:30 - 17:00 in the Foyer and Hall: Mancini 3A Saturday 9 December, 08:30 - 09:30 in the Foyer and Hall: Mancini 3A

Welcome reception: Thursday 7 December, 18:30 - 19:15 in the Foyer (Outside Mancini Halls 1 & 2) CONFERENCE PROGRAMME 2017 Attendee Services 16 9th EDITION

ATTENDEE SERVICES

The Venue Attendee Services

Hotel Savoyen: Located in the heart named after key milestones in the life of the embassy district, close to the of Prince Eugene of Savoy. Belvedere Palace and Botanical An impressive mixture of classic and Gardens. modernity defines the design of the Austria Trend Hotel Savoyen Vienna. A conference at the Hotel Savoyen Surrounded by historical buildings the Vienna is bound to be unforgettable – Austria Trend Hotel Savoyen Vienna just like its namesake, Prince Eugene constitutes the perfect starting point for of Savoy. The hotel effortlessly excursions around Vienna and serves Underground combines old and new, occupying as an upscale backdrop for business Nearest stations: a revitalised building that was once meetings. The nearest station to the venue home to the imperial Austrian state is Wien Rennweg Bahnhof. From and court print works. From the Austria Trend Hotel Savoyen Rennweg 16, 1030 Wien, Austria the station walk south on Rechte outside, the heritage-protected Bahngasse towards Rennweg. After traditional Viennese facade casts its Visit the venue’s website: 25m turn right onto Rennweg and spell on visitors, while indoors light, https://www.austria-trend.at/en/hotels/ continue for 36m. Turn left towards modern architecture, the highest levels savoyen Rennweg and right onto Rennweg and of comfort and contemporary facilities Rechte Bahngasse the Venue is on your left. await. Function rooms have been

Linke Bahngasse

Rechte Bahngasse

Reisnerstrasse Rennweg

Ungargasse Wien Rennweg Bahnhof Savoyen Trend Hotel Rennweg

Fasangasse CONFERENCE PROGRAMME 2017 Discover VIENNA 17 9th EDITION

DISCOVER VIENNA

Surrounded by some of Vienna’s best-known sights, you can explore the nearby Belvedere Palace and its Botanical Garden with banana palms and lemon trees growing in the picturesque pavilion guarding its entrance. You will feel yourself start to blossom as you enjoy a leisurely stroll among countless varieties of exotic flora in the heart of Vienna. In fact, it will seem for all the world like a holiday within a holiday. Admission to the Botanical Garden is completely free of charge. Useful Links:

Airport to City Centre (options) Attendee Services Like the Belvedere, the famous 21er https://www.wien.info/en/travel-info/to-and-around/airport-to-center Haus planned by the visionary architect Karl Schwanzer is just a stone’s throw Vienna Public Transport away from the hotel. Built in 1958 as https://www.wien.gv.at/english/transportation-urbanplanning/public-transport/ the Austrian pavilion for Expo 58 in Getting to and from Airport using various means Brussels, it was reconstructed in Vienna https://www.rome2rio.com/s/Vienna-Airport-VIE/Austria-Trend-Hotel-Savoyen- in 1962 and has provided a space for Vienna contemporary art to thrive ever since. Museums and Exhibitions https://www.wien.info/en/sightseeing/museums-exhibitions With excellent public transport links on our doorstep, Vienna’s historic city centre Need Assistance in Vienna/Useful Numbers: is only a matter of minutes away http://www.vienna4u.at/assistance.html Christmas Markets and Opening Hours: Here you will find the Ringstrasse https://www.austria.info/uk/things-to-do/skiing-and-winter/christmas-markets/ Boulevard Kärntnerstrasse and christmas-markets-in-vienna Mariahilfer shopping streets. Vienna’s Christmas in Vienna – Shops, Choirs, new main station, the Hauptbahnhof is just a couple of minutes’ walk from the http://www.visitingvienna.com/entertainment/christmas-in-vienna/#lights hotel. If you want to unwind after a busy Events in Vienna day or experience the capital’s nightlife, https://events.wien.info/en/ two urban hotspots – Karlsplatz and the Museums Quartier are right around the corner from the hotel. Contemporary outdoor spaces set the scene for some serious people watching. There are always new galleries, bars and clubs to discover in this part of town. CONFERENCE PROGRAMME 2017 Supporting Organisations 18 9th EDITION

SUPPORTING ORGANISATIONS Attendee Services The World Health Organisation medicine, epidemiology, biology, key players in the adolescent health (WHO) designated the University of pediatrics, pedagogy, psychology, field to access and discuss international St Andrews’ School of Medicine as its public health, public policy, and research findings on adolescent health, Collaborating Centre for International sociology. The study has therefore to consider current challenges and Child and Adolescent Health Policy involved cross-fertilization of a range opportunities within pediatric clinical (WHO CC) in October 2013. This of perspectives that has resulted in an practice, and to find solutions to some prestigious appointment endorses innovative scientific framework which of the most pressing issues facing the international research and policy- captures the contextual environment young people today. influencing work of the School’s in which young people live thus leading researchers in the field of allowing us to gain an insight into population and behavioural health determinants and possible mediators sciences. The WHO CC has several and moderators of young people’s strands of work related to social health. As such, HBSC has earned a determinants of health and prevention reputation as a unique provider of key of health inequalities, reduction of internationally comparable statistics youth violence, and prevention of of the health and health-related risk behaviours such as drug use. behaviours of young people. Additionally, it seeks to use research to inform policy and practice aimed This conference is the third of its at improving young people’s health, kind to bring together the Health well-being, health behaviours, and Behaviour in School-aged Children supportive social contexts. In this study, the Excellence in Pediatrics regard, the WHO CC works closely Institute and the WHO Collaborating with key stakeholders including the Centre for International Child and Health Behaviour in School-Aged Adolescent Health Policy to build Children (HBSC) study to increase knowledge, foster dialogue and its policy impact and knowledge progress innovation in research and exchange efforts. practice within the field of children and adolescent health. The HBSC The HBSC is an international alliance study provides secular trends across of researchers that collaborate on countries for a wide variety of key the WHO collaborative cross-national measures within adolescent health. survey of school students, Health Pediatricians are in a unique position Behaviour in School-aged Children. to critically examine this data, Initiated in the early 1980’s, the study contextualise it, and use it to support collects data every four years on and promote healthy behaviours in 11-, 13- and 15-year-old boys’ and the young people they care for. The girls’ health and well-being, social WHO CC advocates on a number of environments and health behaviours. adolescent health issues and The research venture dates back to policy recommendations aimed at 1982 and shortly thereafter it was national and international bodies. All adopted by the WHO Regional Office in all, it will be an excellent opportunity for Europe as a collaborative study. to make research and data relevant HBSC now includes 48 countries and to practitioners, as well as to better regions across Europe and North familiarise researchers with the America. This collaboration brings challenges and opportunities of pediatric in individuals with a wide range of clinical practice. This event will provide expertise in areas such as clinical a unique collaborative opportunity for CONFERENCE PROGRAMME 2017 Supporting Organisations 19 9th EDITION

The Leadership Foundation is The Confederation of Meningitis Along with World Meningitis Day, a membership organisation that Organisations (CoMO), is an CoMO is involved in a number delivers leadership development international not-for-profit member of other projects. In April 2015, and consultancy advice to higher organisation working to reduce the CoMO launched the Life Course education institutions in the UK incidence and impact of meningitis Immunisation initiative, which and around the world. The focus of and septicaemia worldwide. CoMO aims to increase awareness of the Leadership Foundation’s work was founded in September 2004 at vaccine inequalities and the need is to improve the management the World Conference of Meningitis for immunisation throughout life by Attendee Services and leadership skills of existing Organisations when delegates from working with vaccine advocates, other and future leaders of higher across the globe agreed to work civil society organisations, healthcare education. The services provided together in the fight against meningitis. professionals and policy makers. include consultancy, leadership Bringing people together is an development programmes and essential part of what we do. CoMO If you are interested in learning events, including a major series brings together patient groups, health more about the work we do, please of events for governors. This work professionals and organisations, contact [email protected]. is supported by a highly regarded meningitis survivors and families research and development from more than 25 countries to help programme that underpins prevent meningitis worldwide. the leadership development programmes and stimulates Our member organisations are innovation. charities and individuals that share the aims of raising awareness, educating, The Leadership Foundation has supporting families and advocating a small team of experienced for the use of vaccines to prevent leadership and organisational meningitis. We connect our members, development professionals drawn providing resources to a strong global from higher education, other parts network so that they can share their of the public sector, and also from experiences to strengthen one another the private sector. Much of the and to deliver their objectives in the Leadership Foundation’s work is communities that they serve. All year delivered in partnership with the round we strive to raise awareness of higher education sector and other the signs and symptoms of meningitis partner organisations. and septicaemia, how to prevent its www.lfhe.ac.uk occurrence by vaccination, and the devastating effects it can have on a person and their loved ones. World Meningitis Day on April 24 each year is one of our most important activities and when we and our members work to bring meningitis to the top of the agenda. There is much work to be done to ensure vaccines to prevent meningitis and septicaemia are freely available worldwide. CoMO advocates for these vaccines to be available and supports its members in their efforts to do the same. CONFERENCE PROGRAMME 2017 MEDICAL BOOKSHOP 20 9th EDITION

MEDICAL PUBLISHING BOOKSHOP PARTNER Attendee Services Wisepress Medical Bookshop A home for scientifically sound, 15 Lyon Road, Merton fully open access and peer- London, SW19 2RL, UK reviewed health research, Cogent Contact: Ben Powell, Bookshop Medicine offers authors a fast and Manager affordable option for the publication Phone: +44 20 8715 1812 of their work. The journal publishes Fax: +44 20 8715 1722 experimental, translational and [email protected] clinical approaches across all areas www.wisepress.com of biomedical sciences and clinical research and practice. Wisepress.com, Europe’s leading conference bookseller, has a Cogent Medicine hosts supporting complete range of books and journals supplementary material and data relevant to the themes of the meeting. files via the online repository figshare Books can be purchased at the stand and article level metrics are available or, if you would rather not carry them, on all articles and offer a complete posted to you – Wisepress will deliver overview of how people are engaging worldwide. In addition to attending with research. All articles published 200 conferences per year, Wisepress in the journal are freely available to has a comprehensive medical and access online. scientific bookshop online with great offers. As part of Taylor & Francis Group we are building on solid foundations and maintain the traditional values and high standards of an organization with more than 200 years of experience serving the research community. 2017 9th EDITION

CONFERENCE PROGRAMME SCIENTIFIC PROGRAMME AND DAILY SCHEDULE ScientificProgramme and Daily Schedule CONNECT & LEARN WITH EIP THROUGHOUT THE YEAR INTRODUCING FREE-TO-VIEW WEBINARS FROM EIP Hosted and Promoted Every Month to 45,000 Pediatric Healthcare Professionals Across the Globe.

Taking the education and learning outside the conference halls. Update your skills and Knowledge from anywhere at anytime. Register for free for upcoming webinars throughout 2018. Select the webinar that are of interest to you.

• All online sessions are led by one of EiP’s expert speakers covering the latest developments and practical advice in pediatrics. • Plus, as a 2017 Conference attendee you are given free access to all EIP Online recorded sessions from the Conference from Vienna, The EIP Spot the Early Signs Webinars, The Influenza Knowledge Transfer Series on Seasonal Flu Vaccines and Past the Conference Presentation Library. http://eip-pediatrics-community.ineip.org/upcoming_webinars

ORGANISED BY Improving Child Health www.ineip.org Globally Globally Child Health Improving internationalcme atwww.ama-assn.org/go/ found be can credit AMA to credit EACCME convert to process the on Information 1Credits™. Category PRA AMA of number equivalent an to credits EACCME may convert physicians Association, Medical American the and Specialists ofMedical Union European the between agreement an Through educational activity. the in spent actually he/she that credit of hours those only claim should specialist medical Each certificate. attendance your on mentioned be will credits CME external European of hours designated exact The www.uems.net. (UEMS), Specialists Medical of Union European ofthe institution an is EACCME The specialists. medical for activity CME provide to (EACCME) for Continuing Education Medical Council Accreditation European by the accredited is Conference 2017 Pediatrics in Excellence The 17 amountconferencecredits AND SESSION EVALUATIONS CONTINUING MEDICAL EDUCATION (CME) European CMEcredits (ECMEC®s) 9th Excellence in Pediatrics Conference 2017 has beenaccredited 17 2017 9 th th EDITION . Continuing MedicalEducation (EACCME®) European Accreditation Council for

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Scientific Programme and Daily Schedule CONFERENCE PROGRAMME 2017 DAILY PROGRAMME THURSDAY, 07 DECEMBER 2017 24 9th EDITION

DAILY PROGRAMME

08:00 REGISTRATION DESK OPENING

Scientific Programme and Daily Schedule Daily and Programme Scientific 08:30-09:30 COFFEE START (Foyer and Hall: Mancini 3A)

09:30-10:45 OPENING CEREMONY & PLENARY ADDRESSES

Conference Chairs’ Welcome:

TERENCE STEPHENSON JO INCHLEY JOAN-CARLES SURIS Nuffield Professor of Child HBSC International Institute of Social and Health, Institute of Child Health, Coordinator, University of St Preventive Medicine and UCL, Chair General Medical Andrews School Department Council (UK) 2015-2018, Former of Medicine, of Pediatrics Lausanne Chair, UK Academy of Medical United Kingdom University Hospital, Royal Colleges 2012-2014, Past Switzerland President, Royal College of Paediatrics and Child Health 2009-2012, United Kingdom

2017 Plenary Addresses from the Co-Chairs

Obesity and Physical Activity: The Next Generation JO INCHLEY HBSC International Coordinator, University of St Andrews School of Medicine, United Kingdom

Learning Objectives • Review global trends in child and adolescent obesity • Examine key risk factors for overweight and obesity and how these have changed in recent years • Consider the evidence for effective approaches to obesity prevention in children and adolescents

Sex Drugs and a Bit of Acne: Today’s Adolescents JOAN-CARLES SURIS Institute of Social and Preventive Medicine and Department of Pediatrics Lausanne University Hospital, Switzerland

Learning Objectives • Recognize the changes in adolescent health priorities over the last 30 years • Identify the current challenges in adolescent health • Acknowledge the importance of integrating youth’s opinions in policy making DAY 1 DAY Presentation1> Presentation1> Presentation3> Presentation2> Presentation3> Presentation2> 11:00-13:00 11:00-13:00

2017 9 th th EDITION THURSDAY, 07DECEMBER2017 ADOLESCENT MEDICINE Karlstad University and Adolescent MentalHealth(CFBUPH)at founder oftheCentreforResearchon Child Professor ofPublicHealth,Directorand Psychology, Babes-BolyaiUniversity Principal InvestigatorHBSC,Departmentof Founder andCreator Teen HealthWeek Southampton Gastroenterologist, UniversityHospital Professor, ConsultantPaediatric Hospital and Immunologyat Alder HeyChildren’s Consultant inPaediatricInfectiousDiseases MC UniversityMedicalCenterRotterdam Department ofGeneralPractice.Erasmus General Practitioner, Assistant Professor, GIJS ELSHOUT, The Netherlands for FrontlinePaediatricians General Practice-FebrileChildreninPrimaryCareTheLatestPractical CURT HAGQUIST, Sweden Consequences forEveryday LifeofMentalHealthProblems Among Adolescents ADRIANA BABAN,Romania Adolescents Well-being inRomania:LinkingDataandPractice LAURA OFFUTT, USA Teen HealthWeek: Advocating for Young PeopleasaClinician Moderator: CURTHAGQUIST AD1: Sectionon ADOLESCENT WELLBEING MARK BEATTIE, UnitedKingdom Functional Abdominal Pain ANDREW RIORDAN,UnitedKingdom Pyrexia ofUnknownOrigin Moderator: PE1: SectiononGENERAL PEDIATRICS PART 1 PEDIATRICS ANDREW RIORDAN CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: problems Consider howcontextual conditionsaffect theimpactsofadolescents’ mentalhealth Elucidate genderdifferences in impactsofmentalhealthproblemsamongadolescents and perceivedconsequences Understand therelationshipbetweenadolescents’ self-reported mentalhealthproblems Highlight preventiveinterventionsthatcounteractriskfactors Outline theimpactofadversitiesonadolescentswell-being Understand thesocialcontextofadolescents’ healthinRomania youth healthinyourcommunities Consider waystoparticipateandpromote Teen HealthWeek asameanstoimprove engagement, aswelladvocacyforyouthhealthissues Discuss how Teen HealthWeek canbeanopportunityforyouthhealtheducationand Week Learn about Teen HealthWeek: history, whatitis,andwhywehaveGlobal Teen Health Consider apracticalapproachinthechildwithrecurrentabdominalpain based managementandoutcome Review thebiophyschosocialmodeloffunctionalpain-including:riskfactors,evidence Understand theepidemiology, classificationandaetiologyofrecurrent AbdominalPain Know whichtestmayhelpdiagnosechildrenwithPUO Know thecommoncausesofPUOinchildren Know thedifference betweenPUOand“Feverwithoutsource” Using safety-nettingeffectively infebrilechildren Providing toolstoadequatelyassessafebrilechild Gaining knowledgeabouttheepidemiologyofvariouscausesfeverinchildren |MORNINGSESSIONS THURSDA Y , 07 DECEMBER 2017 , 07 DECEMBER Advice Also availablethrough EIP Online Mancini 2Hall Mancini 1Hall 25

Scientific Programme and Daily Schedule

26 esico- Turin Room Turin Wien Room Mancini 3B Hall EIP Online EIP Also available through , 07 DECEMBER, 07 2017 Y THURSDA | MORNING SESSIONS | MORNING Understand the progression of the gut microbiome in healthy infants and young children microbiome development Review factors that affect Consider what interventions are available to modify the developing microbiome and have evidence of health benefits An understanding of Vesico Ureteric Reflux (VUR) - an anatomic and functional disorder Ureteric Reflux (VUR) - An understanding of Vesico that must be diagnosed as soon as possible after birth hydronephrosis, UTI and Reviewing how VUR present in 3 main distinct groups: advanced reflux nephropathy current treatment options An overview of the standard imaging tests to use and and renal failure What must be done to prevent the kidney damage Understand the normal development of the gastrointestinal microbiota after birth Understand the impact that the gastrointestinal microbiota can have in modulating the health of premature infants Appreciate the place that probiotics may have in reducing the risk of necrotizing enterocolitis Understand basic aspects of human microbiome function in paediatric heath Consider broader context of microbial influences on respiratory health and disease, including those of residential commensals Consider complex microbial interactions instead of one pathogen one disease concept as basis for respiratory infection Vigilance, surveillance, containment and control in relation an outbreak. surveillance, Vigilance, evidence based interventions and resource allocations. and Effective Learning from the event and already reported outbreaks. of neonatal RDS Understand the epidemiology and the clinical relevance a problem in daily practice Review the topics in neonatal RDS that still can represent Consider old and new RDS diagnostic strategies Learning Objectives: • • • Moderator: JUDIT VILLOSLADA Learning Objectives: • • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • DAILY PROGRAMME DAILY CONFERENCE PROGRAMME NEONATOLOGY & EARLY LIFE PEDIATRICS EARLY & NEONATOLOGY Part C - Modulating the Gut Microbiome in Early Life – Impact on Future Health? ALLEN, United Kingdom STEPHEN Part B - Evolution of Respiratory Tract Microbiota and its Relation to Respiratory Health in Children Part B - Evolution of Respiratory Tract United Kingdom BOGAERT, DEBBY INF1: INFLUENCE OF MICROBIOTA ON ASPECTS OF CHILD HEALTH ON INF1: INFLUENCE OF MICROBIOTA Chair: SIMON KROLL - Gastrointestinal Microbiota in Neonates and Necrotizing Enterocolitis A Part SIMON KROLL, United Kingdom Integrative Prenatal Diagnostic and Postnatal Management for Congenital Malformation - V Integrative Prenatal Diagnostic and Postnatal ureteral Reflux SEBASTIAN IONESCU, Romania Diagnosing Neonatal Respiratory Distress Syndrome (RDS): An Update for Pediatricians Syndrome (RDS): Diagnosing Neonatal Respiratory Distress FRANCESCO RAIMONDI, Italy ROY PHILIP Moderator: ROY and Effectiveness Approaching with Evidence Neonatal Outbreaks: Ireland K. PHILIP, ROY NE1: Section on NEONATOLOGY NE1: Section on OP1: ORAL PRESENTATIONS OP1: ORAL Professor of Paediatrics and Honorary Consultant Paediatrician, Liverpool School of Medicine Tropical Profesor of Pediatric Surgery, Clinica de Profesor of Pediatric Surgery, Chirurgie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii Maria Sklodowska Curie Professor of Paediatrics and Molecular Infectious Diseases, Imperial College and St Hospital Mary’s Professor of Paediatric Infectious Diseases and Honorary Consultant in paediatric infectious diseases, Center for Inflammation Research, University of Edinburgh Consultant Paediatrician and Neonatologist,Consultant Paediatrician and of Neonatology, Adjunct Clinical Professor University Maternity Hospital Limerick & GEMS, University of Limerick Section of Chief, Division of Neonatology, Medical Translational Pediatrics Dept of Sciences, Università «Federico II» di Napoli INFOCUS SESSION THURSDAY, 07 DECEMBER 2017 07 DECEMBER THURSDAY, EDITION th 9 2017

11:00-13:00 11:00-13:00 11:00-13:00 Presentation 2> Presentation 3> Presentation 2> Presentation 3> Presentation 1> Presentation 1> DAY 1

Scientific Programme and Daily Schedule DAY 1 DAY Presentation1> Presentation4> Presentation3> Presentation2> 13:00-14:00 13:00-14:00 14:00-16:00

2017 9 th th EDITION THURSDAY, 07DECEMBER2017 and Children’s Health,KarolinskaInstitutet Assistant Professor, DepartmentofWomen’s University Children’s Hospital inKrakow Faculty ofMedicine,InstitutePediatrics, Jagiellonian University, MedicalCollege, Pediatric and Adolescent Endocrinology, Professor, HeadoftheDepartment Pharmacology, UniversityofVirginia Professor Emeritus,Pediatricsand TrustFoundation Newcastle upon Tyne HospitalsNHS Endocrinologist, NewcastleUniversity, University ReaderandConsultantPaediatric FARASAT ZAMAN,Sweden Translational ResearchinPediatricGrowthDisorders JERZY B.STARZYK, Poland Congenital CombinedPituitaryHormoneDeficiency ALAN D.ROGOL,USA Growth -Normaland Abnormal TIM CHEETHAM,UnitedKingdom Thyroid Disordersinthe Young –Whattodo? JOAN-CARLES SURIS,JUDIT VILLOSLADA,CHRISTINA AKRE POSTER VIEWINGS LUNCH BREAK Moderator: TIMCHEETHAM PE2: SectiononENDOCRINOLOGY &GROWTH PEDIATRICS CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME (Mancini3A andFoyer) (LunchtimeViewing Groups&Guided Tours) -Hall:Mancini3A -Group1,2,3 • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: experimental model Which experimentalmethodtochoose?Usingasimpleandfeasiblepreclinical biopsies models ,boneorganculturesmodels,howtousehumangrowthplatebiopsies orbone Methods oftranslationalresearchinpaediatricgrowthdisorders-existingpre-clinical successes/failures andtimeframe From BenchtoBedBench;translationalresearchinpaediatrics–thelimitations, multihormonal replacementtherapyaswelladjustthehydrocortisonedoses Follow-up thepossibleconsecutiveCPHDappearingsignsandoutcomeof clinical manifestationsandhypothalamo-pituitarymagneticresonanceimaging Consider CPHDdiagnosisinpatientsatdifferent agesonthebasisofnon-specific acute life-threateningorchronicconsequences Understand theaetiologyofCongenitalPituitaryHormoneDeficiency(CPHD)andits inhibiting conditions Understand theproperuseofvariousgrowth-promotingagentsforgrowth- Produce adifferential diagnosisforagrowthretardedchild Understand theuseofgrowthchartsinevaluationchildhooddisorders ways ofaddressingthis Reflect onthefactthatmanythyroxinetabletsnevermakeitpastlipsandconsider concentration Develop astrategyforinvestigatingandmanagingthechildwithanelevated interpreting thyroidfunctiontests Understand thesignificanceoflocalreferencerangesandpotentialpitfallswhen | AFTERNOON SESSIONS THURSDA Y , 07 DECEMBER 2017 , 07 DECEMBER Also availablethrough EIP Online Mancini 2Hall TSH 27

Scientific Programme and Daily Schedule

28 Mancini 1 Hall Mancini 3B Hall EIP Online EIP Also available through , 07 DECEMBER, 07 2017 Y THURSDA | AFTERNOON SESSIONS | Discussing the role of nutrition in the first 1,000 days as the window for life style changes and ultimately childhood obesity prevention Understanding the importance of early prevention, even pre-conception, in term to reduce risk in adulthood Bring together specialists to look at the same results: Prevent early risks - reduce later risks - improve adult health Understand the presenting features – how to spot the child with nephrotic syndrome Review recent clinical trials relating to the initial corticosteroid regimen in the child presenting with nephrotic syndrome Outline the management of relapsing disease Learn the importance of having a National Action plan against obesity approved by a National Learn the importance of having Government political actions including daily physical Get insight how a national plan may affect activity in schools and other institutions have a written Appreciate the importance that school, kindergarten policy on diet and physical activity using psychological techniques Understand the basis of a professional conversation in childhood obesity effective Review appropriate literature in medicine and psychology therapy in childhood obesity Consider ways of learning and training conversational Latest Learning Objectives: at: http://eip-pediatrics-conference.ineip.org/ Available Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • DAILY PROGRAMME DAILY CONFERENCE PROGRAMME PEDIATRICS PE3: Section on CHILDHOOD OBESITY PE3: Section on Chair: KURT WIDHALM Obesity Childhood to Tackling Approach Multisystem A for the Paediatrician? Topic A EAROC Section - Obesity: NEPHROTIC SYNDROME: Management of Childhood Nephrotic Syndrome Briefing with Q&A NICK WEBB, United Kingdom Early-life Nutrition and Future Health: Will They be Giants? Will Early-life Nutrition and Future Health: ANGELO PIETROBELLI, Italy Sedentary Behaviours in Children AZNAR, Spain LUIS MORENO CARL-ERIC FLODMARK, Sweden Family/Systemic Therapy in Treating Childhood Obesity Childhood Family/Systemic Therapy in Treating Policies, Politics and Prevention of Pediatric Obesity in Denmark Prevention of Pediatric Obesity in Policies, Politics and INGE LISSAU, Sweden Full Professor at the University of Zaragoza, President of the Spanish Nutrition Society Professor of Pediatric and Nutrition at University Medical Pediatric Unit of Verona Associate Professor at Adjunct School, Pennington Biomedical Research Center Associate Editor – USA, Baton Rouge LA Senior International Journal of Obesity, Physician at Pediatric Clinic Honorary Professor of Paediatric University of Manchester and Nephrology, Consultant Paediatric Nephrologist, Royal Hospital, Manchester Manchester Children’s Associate Professor, Senior Research Associate Professor, Scientist at Clinical Research Unit, Copenhagen University Hospital, Hvidovre, DENMARK and Department of Child Health, Skane University Hospital, Malmø Medical Officer at Swedish National Board of professor Associated and Welfare and Health Malmö at Lund University, WORKSHOP 1: WORKSHOP THURSDAY, 07 DECEMBER 2017 07 DECEMBER THURSDAY, EDITION th 9 2017

14:00-16:00 14:00-14:40 Presentation 4> Presentation 2> Presentation 3> Presentation 1> DAY 1

Scientific Programme and Daily Schedule DAY 1 DAY 14:40-15:20 15:20-16:00 14:00-16:00 15:20-16:00 14:40-15:20 14:00-14:40

2017 9 th th EDITION THURSDAY, 07DECEMBER2017 WORKSHOP 3: PROFESSIONAL DEVELOPMENT Manchester Children’s Hospital,Manchester Consultant PaediatricNephrologist,Royal Nephrology, UniversityofManchesterand Honorary ProfessorofPaediatric Childhood, BMJPublishinggroup Editor inChief, Archives ofDiseasein Immunology Department ofPediatricPneumonologyand Prof. Charité-UniversitätsmedizinBerlin, GEMS, UniversityofLimerick University MaternityHospitalLimerick& Adjunct ClinicalProfessorofNeonatology, Consultant PaediatricianandNeonatologist, Professor ofChildand Adolescent Psychiatry MICHAEL FITZGERALD,Ireland Audience ResponseSession CHILD & ADOLESCENT MENTAL HEALTH: DiagnosisandManagement of Autism & ADHD NICK WEBB,UnitedKingdom Audience ResponseSession CYSTINOSIS: SpottingtheEarlySignsofCystinosis MARK BEATTIE, UnitedKingdom Interactive Workshop PD1: PUBLISHINGWORKSHOP:GETTINGRESEARCHPUBLISHED SUSANNE LAU,Germany Audience ResponseSession RESPIRATORY: PediatricBronchoscopy-Indications forRigidandFlexibleBronchoscopy ROY K.PHILIP, Ireland Audience ResponseSession VACCINE HESITANCY: OvercomingVaccine Hesitancy OP2: ORAL PRESENTATIONS WORKSHOP 2: WORKSHOP 5: WORKSHOP 4: CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME Moderator: JOAN-CARLES SURIS • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: Review theextrarenalcomplicationsand long-termoutcome. Review currenttreatmentoptions,including renaltransplantation Understand thecommonpresentingfeatures ofcystinosis Participate ina‘mock’ editorialcommitteeselectingpapersforpublication Discuss howtowriteforthereader-gettingyourmessageacross Discuss theprocessbywhichjournalsselectpapersforpublication approaches To understandtherisks,disadvantagesandtechnicalrequirementsofdifferent To understandtheadvantagesandpotentialsofoneorotherapproach To reviewthedifferent indicationsforrigidandflexiblebronchoscopies adopt moderndigitalcommunicationstrategies. Promote andsustainexcellentvaccinationcoveragethevaccinecommunityshould How toconverttheresultsofvaccineresearchintoasuccessfulvaccinationprogrammes. building, maintainingandenhancingtrustinvaccination. Measures topromotevaccinationawarenessandhighlightproactiveapproachesfor Understand thespectrumconceptinchildpsychiatry Understand thenewneurodevelopmentalparadigminchildpsychiatry neurodevelopmental disorders Understand thediagnosisandoverlapbetween Autism, ADHD andother | AFTERNOON SESSIONS THURSDA Y , 07 DECEMBER 2017 , 07 DECEMBER Mancini 3BHall Mancini 3BHall Wien Room Wien Room Wien Room Turin Room 29

Scientific Programme and Daily Schedule

30 Mancini 2 Hall EIP Online EIP Also available through , 07 DECEMBER, 07 2017 Y THURSDA | AFTERNOON SESSIONS AFTERNOON | Review the epidemiology, classification and aetiology of Inflammatory Bowel Disease in classification Review the epidemiology, children Discuss the clinical features, investigation, and diagnosis Review the recent advances in management Overview of the microbiota in humans of microbiota in health and disease Effect Evaluating fecal transplant as a future therapy for difficult diseases Learning Objectives: • • • Learning Objectives: • • • Latest Learning Objectives: at: http://eip-pediatrics-conference.ineip.org/ Available Latest Learning Objectives: at: http://eip-pediatrics-conference.ineip.org/ Available

DAILY PROGRAMME DAILY CONFERENCE PROGRAMME COFFEE BREAK (Foyer & Mancini 3A) Microbiome and Feacal Transplant Lebanon AZIZ KOLEILAT, Epidemiology, Diagnosis and Management of Inflammatory Bowel Disease - Recent Advances of Inflammatory Bowel Disease - Recent Diagnosis and Management Epidemiology, United Kingdom MARK BEATTIE, CLAUDIA STEFANUTTI, Italy STEFANUTTI, CLAUDIA KURT WIDHALM, Austria WIDHALM, KURT 2 - Novel exciting treatments of severe forms - PART of Lipoprotein Disorders Genetics and Treatment PE4: Section on GASTROENTEROLOGY PE4: Section on Moderator: KURT WIDHALM – state of the art 1 - Familial hypercholesterolemia of lipoprotein disorders - PART Genetics and treatment Professor, Consultant Paediatric Professor, Gastroenterologist, University Hospital Southampton Associate Professor Makassed University Asthma, & Gastroenterology hospital General General Secretary (PASPGHAN) Vice Arab Society Pediatric Pan foreign affairs, & Nutrition Gastroenterology,Hepatology President of the Austrian Academic Institute Austrian President of the for Clinical Nutrition, Professor (Em.) at the Medical University Vienna MD, PhD Head of Extracorporeal Professor, Unit, Lipid Clinic and Techniques Therapeutic Atherosclerosis Prevention Centre Regional Centre for Rare Diseases Department of Molecular Medicine, ‘Sapienza’ Hospital University of Rome and ‘Umberto I’ PEDIATRICS THURSDAY, 07 DECEMBER 2017 07 THURSDAY, EDITION th 9 2017 16:00-16:30 16:30-18:30 Presentation 4> Presentation 2> Presentation 3> Presentation 1> 1 DAY

Scientific Programme and Daily Schedule DAY 1 Presentation2> Presentation1> Presentation3> 16:30-18:30 16:30-17:30 2017 9 th th EDITION THURSDAY, 07DECEMBER2017 ADOLESCENT MEDICINE WORKSHOP 6: Negev, Beersheva Sciences, BenGurionUniversityofthe Emeritus Professor, FacultyofHealth Frambu ResourceCenterforRareDisorders Promotion andDiseasePrevention Principal Investigator, InstituteforHealth Child and Adolescent Health WHO CollaboratingCentreinInternational Psychology courseandCoDirectorofthe of St Andrews, DirectorofMScHealth Chair inHealthPsychologyatUniversity GERALD HUMPHRIS,UnitedKingdom Ways thatHealthProvidersRespond The EmotionalCuesandConcernsExpressedbyOncologyPaediatricPatientsthe17Different Moderator: GERALDHUMPHRIS AD2: Sectionon ADOLESCENT HEALTH COMMUNICATION BASIL PORTER, Israel Comprehensive CommunityPediatrics COMMUNITY PEDIATRICS: TheGoshenProject: A ModelforImplementing TORUN MARIEVATNE, Norway Seizing GoldenCommunicationOpportunitiesinPediatricConsultations Austria ROSEMARIE FELDER-PUIG,HBSC Health Literacy Assessment in13-to17-yearold Austrians: ResultsandMeasurementProblems CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME • • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: ensure comprehensivecarefortheirpediatricpopulationandfamilies Understand theneedtoworkwithothersfromfieldsofeducationand welfare to national level Understand theneedforpediatricianstobeadvocateschildhealthat localand to showthecentralityandimportanceofhighqualitycommunity-basedpediatric care Use theknowledgeandtoolsacquiredtoeffect thechangerequired inpediatricsettings regarding developmentalandbehavioralissues Understand thedeficienciesinclinicalfieldofCommunityPediatrics, particularly Understand howtorespondchildrenandadolescentsconcernsinamedicalsetting Understand howchildrenandadolescentsexpressemotionsduringconsultations Understand howtoenablechildrenandadolescentsreportsymptoms forward literacy inadolescentshasgainedgeneralacceptanceandproposepotentialpaths Reflect onthefactthatsofarnoneofsuggestedconceptsformeasuringhealth health literacyskillsmaysupportinformedhealth-seekinglifestyles Consider thatduringadolescence,lifelonghealthbehavioursandhabitsdevelop, disease preventionandmanagement Discuss howhealthliteracyhasbecomeanimportantconceptinpromotion, during healthprovider/patientinteractions Learn ataxonomyofclinicianrespondingbasedupon‘providing’ or‘reducing’ space expression duringclinicalencounters Discover thedifferences betweenadultandpaediatricpresentationofemotional Confirm howtorecognisehiddenemotionsinyoungoncologypatients | AFTERNOON SESSIONS THURSDA Y , 07 DECEMBER 2017 , 07 DECEMBER Mancini 3BHall Mancini 1Hall 31

Scientific Programme and Daily Schedule 32 Turin Room Turin Wien Room Mancini 3B Hall ER 2017 B , 07 DECEM, 07 Y THURSDA | AFTERNOON SESSIONS AFTERNOON | Promote breastfeeding as the norm for infant feeding of lactation Become Knowledgeable in the principles and management Develop skills necessary for assessing the adequacy of breastfeeding steps to successful breastfeeding Ten List the key components of the history and examination of the knee List the key components maneuvers Demonstrate proper technique for key examination on the history and exam findings Determine the likely diagnosis of an injured knee based spinal injuries among children and Review the causes of back pain and sports-related adolescents pain and sports-related spinal Understand the possible management options of back when to refer for investigations or injuries among children and adolescents including specialist opinion assessing back pain and sports- Demonstrate the key examination techniques when related spinal injuries among children and adolescents Learning Objectives: • • • • AKRE Moderator: CHRISTINA Learning Objectives: • • • Learning Objectives: • • • BOB SALLIS - Foyer (Outside Mancini Halls 1 & 2) - All Delegates Invited - Foyer (Outside Mancini Halls 1 & 2) - DAILY PROGRAMME DAILY CONFERENCE PROGRAMME WORKSHOP 7: WORKSHOP OP3: ORAL PRESENTATIONS OP3: ORAL WELCOME RECEPTION BREASTFEEDING: Teaching Mothers How to Breastfeed BREASTFEEDING: Teaching GRIVEA, Greece IOANNA COURTNEY KIPPS, United Kingdom COURTNEY MANAGEMENT OF SPORTS INJURIES MANAGEMENT OF Hands on Session • Moderator: BOB SALLIS, USA Associate Professor of Pediatrics and Thessaly Neonatology at the University of Clinical Professor of Family Medicine, Clinical Professor of Family USA, UC Riverside School of Medicine, Sports Medicine Fellowship, Co-Director, Exercise is Kaiser Permanente, Chair, Medicine Fellow and Teaching Principal Clinical Consultant in Sport and Exercise Medicine UCL Health & Exercise Sport, of Institute The WORKSHOP 8: WORKSHOP Essentials of sports-related back pain in children Essentials of sports-related back pain Essentials of the Knee Exam Essentials of the Knee THURSDAY, 07 DECEMBER 2017 07 THURSDAY, EDITION th 9 2017 18:30 16:30-18:00 16:30-18:30 17:30-18:30 Presentation 1> Presentation 2> 1 DAY

Scientific Programme and Daily Schedule DAY 2 DAY Presentation1> Presentation4> Presentation3> Presentation2> 08:00-09:00 09:00-11:00

2017 9 th th EDITION FRIDAY, 08DECEMBER2017 University MedicalCentreGöttingen pediatric neurologicaldiseases(GoRare) and neurometabolicdisordersCentreforrare - Responsiblefordiagnosticoflysosomal Coordinator ofexpertcentre-Clinical Hospital, Sheffield,UnitedKingdom. Diagnostic Service,SheffieldChildren’s Head ofEhlers-DanlosSyndromeNational Hospital, London Lysosomal DisordersUnit,RoyalFree Consultant inInheritedMetabolicDisorders, Barcelona Visiting ProfessorPediatrics,Universityof Hospital. CSICResearchProfessorand Department, SantJoandeDéuChildren’s Diseases (IPER)andHeadoftheGenetics Director oftheInstituteforPediatricRare PEDIATRICS FRANCESC PALAU, Spain Transforming RarityintoKnowledgetoCareforandCureChildrenwithRareDiseases Moderator: UMA RAMASWAMI PE5: SectiononRAREDISEASES ROBERT STEINFELD,Germany Vitamin-Dependent Encephalopathies-CerebralFolateDeficiency AnUpdate GLENDA SOBEY, UnitedKingdom Ehlers DanlosSyndrome-TheNew2017Classification. A ClinicalGuideforPaediatricians UMA RAMASWAMI, UnitedKingdom Emergency Management,InheritedMetabolicDisorders COFFEE START (Foyer&Mancini3A Hall) CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME

|MORNINGSESSIONS • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: dependent encephalopathiesinanearlystageofthedisease Consider diagnosticprocedurestoobtainevidenceandconfirmationofvitamin- encephalopathies Review thesignsandsymptomsaswelltherapeuticoptionsforvitamin-dependent cerebral folatedeficiency Understand thebasicconceptsofvitamin-dependentencephalopathies,inparticular Familiarity withtheclinicalsignsofdifferent typesofEDSinpaediatrics Update onthegenetictestingavailableinthisgroupofconditions Awareness ofthenew2017ClassificationEhlers-DanlosSyndromes First linemanagementandtreatments Basic metabolicemergencyinvestigations When tosuspectaninheritedmetabolicdisorderinasickchild common diseases Rarity asawaytounderstandthecontinuumofpathophysiologybetweenrareand Contextualizing thediagnosisofrarediseasesineragenomicsandgenetictesting Understanding theconceptofrareandundiagnoseddiseasesbeyondprevalence FRIDA Y , 08 DECEM , 08 B ER 2017 ER Mancini 2Hall 33 Harvey Goodwin Hall Harvey Goodwin

Scientific Programme and Daily Schedule

34 Mancini 1 Hall Mancini 3B Hall EIP Online EIP Also available through ER 2017 B , 08 DECEM Y FRIDA Review Clinical Report on Transition and Quality Improvement Model (Six Core Transition Review Clinical Report on Transition) Elements of Health Care Approaches in Primary Care, Children’s Discuss Examples of Six Core Elements Hospitals, School-based Care, Behavioral Health, and Public Health Measures and Results Transition Summarize New Review oro-facial development with special reference to the timing of the development Review oro-facial development with special reference of the dentition through childhood to adulthood and Re visit the recognition of healthy oro-facial tissues their importance in general health interface through infancy to Illustrate the diagnostic importance of the dental/ medical adolescence Appraised) project (Models of Child Health Outline the aims and methods of the EU MOCHA Describe the key findings from the study around access to care, health professional communications (consultation and information) , and transition issues in those with complex care needs People Young Contextualise these with their own practice and WHO Strategy for Children and Understand that the transition from pediatric to adult care could represents a critical issue for patient with chronic and rare disease an example of transition care for diabetes type I Offer an example of transition care for a endocrine rare and severe disease Offer Review the epidemiology of Oro-facial Injuries Review the epidemiology Outline the classification of Oro-facial Injuries of Oro-facial Injuries in the primary Illustrate the short-term and long-term management and permanent Dentition routine physical examination of a child Examination of the oral cavity is a crucial part of the disease Dental decay is the most common chronic paediatric behavioural modifications Dental decay is largely preventable by nutritional and Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • | MORNING SESSIONS | MORNING DAILY PROGRAMME DAILY CONFERENCE PROGRAMME PEGGY McMANUS, USA PEGGY LUISA DESANCTIS, Italy DESANCTIS, LUISA Approach for Primary and Quality Improvement A Six Core Elements of Health Care Transition: Specialty Care The Transition for Endocrine Complex Diseases The Transition AD3: Section on TRANSITION TO ADULT CARE ADULT AD3: Section on TRANSITION TO Moderator: JOAN-CARLES SURIS Across Europe Appraising the Differing Models of Child Health that are Used Project - The MOCHA MITCH BLAIR, United Kingdom Oral Health and the Implications for Systemic Health Oral Health and the Implications for Systemic Australia RICHARD WIDMER, The Front End of Paediatrics: Oral Health and Nutrition The Front End of Paediatrics: Oral Health COLIN MICHIE, United Kingdom PE6: Section on ORAL HEALTH ORAL PE6: Section on Moderator: RICHARD WIDMER for Oro-Facial Injuries in Children Aid” Important “First Australia RICHARD WIDMER, Got Transition and The National Alliance to The National and Transition Got Advance Adolescent Health Head of Department & Senior Staff Head of Department & Senior Staff Children’s Specialist, Paediatric Dentistry, , Sydney Childern’s Hospital at Westmead Hospital Network Professor of Paediatrics and Child Public Health; Principal Investigator University of Turin Head of Department & Senior Staff Staff Head of Department & Senior Children’s Specialist, Paediatric Dentistry, , Sydney Childern’s Hospital at Westmead Hospital Network Consultant Paediatrician, Royal National Orthopaedics Hospitals, Imperial and University College ADOLESCENT MEDICINE PEDIATRICS FRIDAY, 08 DECEMBER 2017 08 DECEMBER FRIDAY, EDITION th 9 2017

09:00-11:00 09:00-11:00 Presentation 2> Presentation 3> Presentation 2> Presentation 3> Presentation 1> Presentation 1> DAY 2

Scientific Programme and Daily Schedule DAY 2 DAY Presentation1> Presentation4> Presentation3> Presentation2> 10:15-14:15 11:30-13:30 09:00-11:00 11:00-11:30

2017 9 th th EDITION FRIDAY, 08DECEMBER2017 COFFEE BREAK(Mancini3A andFoyer) PEDIATRICS Hospital Paediatric Allergy UniversityCollegeLondon Consultant inGeneralPaediatricsand University CollegeLondonHospital Consultant Paediatricianand Allergist, University CollegeLondonHospital Specialist Paediatric Allergy Dietitianat Paediatrics, UniversitairZiekenhuisBrussel Professor, HeadofDepartment • • • • Learning Objectives: Chief ExecutiveoftheLeadershipFoundationforHigherEducation ALISON JOHNS,UnitedKingdom PROFESSIONAL DEVELOPMENT Interactive Workshop PD2: LEADERSHIP &TEAMDEVELOPMENT Lunch ServedDuringtheMeeting- Agenda availableonpage47-48 2nd LifeCourseImmunisationFocusGroup-Opento All -Coffee and LIFE COURSEIMMUNISATION LEANNE GOH,UnitedKingdom Anaphylaxis PENNY SALT, UnitedKingdom Interactive CaseStudiesinPaediatric Allergy SOPHIA KALLIS,UnitedKingdom Elimination DietsasaDiagnosticTool YVAN VANDENPLAS, Belgium Practical Advice forChildrenwithCow’s Milk Allergy Moderator: LEANNEGOH PE7: SectiononDIET& ALLERGIES HEALTH POLICY & ADVOCACY FOCUSGROUP MEETING And howcanyoupromoteandempowercollaborativeteamwork? What arethecharacteristicsofbothhighperforminganddysfunctionalteams? What areyourstrengths,passions,blindspotsandaspirationsfordevelopment? What sortofleaderdoyouwanttobe? CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME |MORNINGSESSIONS • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: Can wepredictwho isatriskoffatalanaphylaxis? What istheriskandimpact? histories.) What isanaphylaxis?(Focusonfood triggered anaphylaxis,illustratedwithrealcase Using realcasestudies Interactive discussionsonmanagement Common paediatricallergypresentations Consider theimpactofmultiplefoodeliminations Practical implementationofelimination–reintroductionsequence Understand theroleofeliminationdietsindiagnosingfoodallergy Know aboutthemanagementoptions Better understandhowtodiagnosecow’s milkallergy Know thesymptomsofcow’s milkallergyandhowtodiagnoseit Programme Director, LeadershipFoundationforHigherEducation DOUG PARKIN, UnitedKingdom FRIDA Y , 08 DECEM , 08 B ER 2017 ER Also availablethrough EIP Online Mancini 2Hall Wien Room Turin Room 35

Scientific Programme and Daily Schedule

36 Turin Room Turin Mancini 1 Hall Mancini 3B Hall EIP Online EIP Also available through ER 2017 B JOAN-CARLES SURIS, , 08 DECEM Y FRIDA

Improve your knowledge on systematic skin examinations diagnoses of a selection of relevant Recognize the clinical features and differential pediatric skin affections Be prepared to initiate the adequate first step diagnostic approaches Understand the first line treatment and management of these skin problems Define the signs and symptoms of sports related concussion Define the signs and symptoms of sports related Summarize the true risks of repeated concussions related concussions Design an evidence based strategy for managing sports approaches in the treatment of cerebral palsy therapeutic Review different of cerebral palsy Discuss the lack of guidelines in the rehabilitation/treatment Stress the importance of further research Improve your knowledge on systematic skin examinations diagnoses of a selection of relevant Recognize the clinical features and differential pediatric skin affections Be prepared to initiate the adequate first step diagnostic approaches Understand the first line treatment and management of these skin problems Understand common headache presentations in childhood Understand common headache trials in headache treatment Review recent large prospective lifestyle and medication approaches Consider holistic treatment strategies involving both concussion among children and Review the signs and symptoms of sports-related adolescents concussion among children and Understand the management options of sports-related adolescents opinion in managing sports-related Explain when to refer for investigations or specialist concussion among children and adolescents Learning Objectives: • • • • AKRE Moderator: CHRISTINA Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • • Learning Objectives: • • • Learning Objectives: • • • | MORNING SESSIONS | MORNING DAILY PROGRAMME DAILY CONFERENCE PROGRAMME LUNCH BREAK | POSTER VIEWINGS 2 (Lunchtime Viewing Groups & Guided Tours) - Hall: Mancini 3A - Group 1, 2 , 3 - - Hall: Mancini 3A Tours) Groups & Guided (Lunchtime Viewing CHRISTINA AKRE VILLOSLADA, CHRISTINA JUDIT Test Yourself in Pediatric Dermatology. An Interactive Case-oriented Workshop - PART 2 - PART An Interactive Case-oriented Workshop in Pediatric Dermatology. Yourself Test KUNZ, Germany BARBARA Audience Response Session 1 - PART An Interactive Case-oriented Workshop in Pediatric Dermatology. Yourself Test GYSEL, Belgium DIRK VAN PE9: Section on DERMATOLOGY: INTERACTIVE PEDIATRIC DERMATOLOGY CASES DERMATOLOGY INTERACTIVE PEDIATRIC PE9: Section on DERMATOLOGY: Different Therapeutic Approaches in the Treatment of Cerebral Palsy Approaches in the Treatment Different Therapeutic POLOVINA, Croatia SVETISLAV Update on Concussions: Why the Hysteria Around the Injury May be a Threat to Health Around the Injury May be a Threat Update on Concussions: Why the Hysteria BOB SALLIS, USA What is Concussion and How to Manage it? What is Concussion and How to Manage KIPPS, United Kingdom COURTNEY PE8: Section on NEUROLOGY PE8: Section on Moderator: BOB SALLIS Management of Headaches KENNETH J. MACK, USA OP4: ORAL PRESENTATIONS OP4: ORAL Specialist Dermatologist, Direction of Dermatologikum Paediatric dermatology, Hamburg, Board member of the European Society of Pediatric Dermatology (ESPD) Clinical Professor of Family Medicine, UC Riverside School of Medicine, USA, Sports Medicine Fellowship, Kaiser Co-Director, Exercise is Medicine Permanente, Chair, Specialist Physical Medicine and Rehabilitation, Polyclinic for Physical Medicine and Rehabilitation Head of the Department of Pediatrics, O.L Aalst. Board member and Hospital Vrouw of the ESPD Treasurer former Professor, President Child Neurology President Professor, Adolescent Mayo Clinic, Child and Society, Neurology Fellow and Teaching Principal Clinical Consultant in Sport and Exercise Medicine UCL Health & Exercise Sport, of Institute The PEDIATRICS PEDIATRICS FRIDAY, 08 DECEMBER 2017 08 DECEMBER FRIDAY, EDITION th 9 2017

11:30-13:30 11:30-13:30 11:30-13:30 13:30-14:30 Presentation 4> Presentation 2> Presentation 2> Presentation 3> Presentation 1> Presentation 1> DAY 2

Scientific Programme and Daily Schedule DAY 2 DAY Presentation1> Presentation3> Presentation2> Presentation 4> 14:30-16:30 13:30-14:30

2017 9 th th EDITION FRIDAY, 08DECEMBER2017 • • • Basic eczemaskincare University CollegeLondonHospital Consultant Paediatricianand Allergist, PENNY SALT, UnitedKingdom PEDIATRICS in Larissa University of Thessaly, SchoolofMedicine Professor andChairmanofPaediatricsatthe Independent Expert Honorary ProfessorofPediatricsand Hospital and Immunologyat Alder HeyChildren’s Consultant inPaediatricInfectiousDiseases • • • Learning Objectives: Organisations (CoMO) Co-ordinator forEuropeand Africa,Confederation ofMeningitis ELENA MOYA, Spain (delivered bytheConferenceFaculty)15minuteseach-Seatingfor25 PRACTICAL HOWTO... DEMONSTRATION SESSIONS European Attitudes toVaccination andMeningitis- A Combined Approach GEORGE SYROGIANNOPOULOS,Greece Have ourexpectationsbeenattainedbypneumococcalconjugatevaccines? CATHERINE WEIL-OLIVIER,France The ImpactofRoutineNationalImmunizationProgrammeson Antibiotics ThroughoutEurope ANDREW RIORDAN,UnitedKingdom Should We Use Antipyretics BeforeVaccination? Moderator: PE10: SectiononINFECTIOUSDISEASES Effective applicationofemollients Bathing thechildwitheczema Avoiding triggers Identify differences inlevelsofmeningitisawareness inadolescentsacrossEurope Importance ofacombinedapproachto healthcommunication:valueandperspectives Consider theattitudestovaccinationin adolescentsacrossEuropeancountries ANDREW RIORDAN CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME • • • Milk alternatives College LondonHospital Specialist Paediatric Allergy DietitianatUniversity SOPHIA KALLIS,UnitedKingdom Creative useofmilkalternativesincooking alternatives Practical tipsforthesuccessfulintroductionofmilk Review of hypoallergenic formulas and dairy free milks | AFTERNOON SESSIONS • • • • Learning Objectives: • • • Learning Objectives: • • • • Learning Objectives: Evaluate thereplacementphenomenon health amongdifferent countries Explore thedifferences intheimpactofpneumococcalconjugatevaccines onpublic populations Understand theextentofreductionpneumoniaandotitismediainpaediatric Learn theremainingburdenofpneumococcalinvasivedisease Identify thepointsofresidualhurdlesacrossEurope antibiotics prescription Importance ofanapproachcombininglargevaccinationcoverageandgoodpracticesin Consider theglobalimpactofroutinenationalimmunizationacrossEuropeancountries Don’t giveibuprofenbeforeimmunisation–itdoesn’twork Do giveparacetamoloribuprofentorelievepainanddistressafterimmunisation Don’t routinelygiveparacetamolbeforevaccines,excepttoinfantsBexsero At theendofsessionattendeeswillknow“do’s anddon’ts” Honorary ProfessorofPediatricsandIndependentExpert CATHERINE WEIL-OLIVIER, France FRIDA Y , 08 DECEM , 08 • • • Adrenaline autoinjectors London Hospital Paediatric Allergy UniversityCollege Consultant inGeneralPaediatricsand LEANNE GOH,UnitedKingdom Written allergyactionplans Adrenaline autoinjectortechnique anaphylaxis Educating patientsonhowtorecognise B ER 2017 ER Also availablethrough EIP Online Mancini 3A Hall Mancini 2Hall 37

Scientific Programme and Daily Schedule Metabolic Diseases Metabolic 38 Mancini 1 Hall Early diagnosis can make a difference. Early diagnosis can make Spot the Early Signs Spot Education Program Education Mancini 3B Hall ER 2017 B , 08 DECEM Y FRIDA Reviewing the signs that should raise a high suspicion of Gaucher disease Reviewing the signs that should raise a high suspicion diagnosis of the three clinical phenotypes Differential When to start treatment? What are biomarkers and why do we need them? Are there reliable biomarkers for diagnosis, early identification of organ involvement and prognosis of lysosomal storage disorders? What tool scan we use to identify new biomarkers? of inborn errors Storage Disorders (LSDs) are a large group Understand how Lysosomal of metabolism characterized by specific accumulated metabolites; Review how clinical manifestations are broad, usually involve multiple organs, and have disease groups: overlap between different Explore how neurological manifestations are the most common presentation: LSDs diagnosis of neurological regression, epilepsy should be considered in the differential skeletal abnormalities, and/or multisystem disease (dysmorphism,hepatosplenomegaly, cardiac disease,….) Examining Urine oligosaccharides and glycosaminoglycan (GAG) screening as useful tools to identify LSDs-Definitive diagnosis can be made by enzyme and/or molecular analysis; Concluding that most of LSDs are inheritable diseases and a proper diagnosis is important in order to provide appropriate genetic counseling. Understand the dynamics of normal motor development –demonstration Understand the dynamics qualitative aspects of normal motor in quantitative and Consider differences development normal motor development Emphasize the importance of recognizing and understanding in motor development in order to spot out the children with abnormalities metabolism Understand the pathophysiology of neonatal bilirubin in daily practice Review the topics that still can represent a problem Consider the available strategies to solve current issues Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • • • Learning Objectives: • • • Learning Objectives: • • • | AFTERNOON SESSIONS | DAILY PROGRAMME DAILY CONFERENCE PROGRAMME FRANCOIS EYSKENS, Belgium PATRICIO AGUIAR, Portugal PATRICIO 3 SES - Metabolic Disorders Training an Early Diagnosis Storage Diseases in Order to Make Spotting the Signs of Lysosomal SES - Metabolic Disorders Training 2 SES - Metabolic Disorders Training Storage Disorders? Need Better Biomarkers in Lysosomal Fabry Disease - Do We SES1: PART OF THE SPOT THE EARLY SIGNS WEBINAR SERIES SIGNS WEBINAR EARLY OF THE SPOT THE SES1: PART RAMASWAMI Moderator: UMA 1 SES - Metabolic Disorders Training in the Pediatric Population Gaucher Disease: Spot the Early Signs Italy CIANA, GIOVANNI Neonatal Hyperbilirubinemia in 2017: An Update for Pediatric HCPs Neonatal Hyperbilirubinemia in 2017: FRANCESCO RAIMONDI, Italy NE2: Section on NEONATOLOGY NE2: Section on Moderator: FRANCESCO RAIMONDI of Life Year in the First Normal Motor Development POLOVINA, Croatia ANDREA Regional Coordinating Centre for Azienda Ospedaliero- Rare Diseases, Universitaria”S.Maria della Misericordia”, Udine Adult Clinic, Inherited Metabolic Disorders Reference Center in Inherited Metabolic Disorders. Centro Hospitalar Lisboa Norte (Hospital de Santa Maria), Lisbon Professor, CEMA-Centrum Erfelijke Metabole Erfelijke CEMA-Centrum Professor, Aandoeningen Specialist Physical Medicine and Specialist Physical Medicine Rehabilitation, Polyclinic for Physical Medicine and Rehabilitation Section of Chief, Division of Neonatology, Medical Translational Pediatrics Dept of Sciences, Università “Federico II” di Napoli SPOT THE EARLY SIGNS SPOT THE EARLY NEONATOLOGY FRIDAY, 08 DECEMBER 2017 08 DECEMBER FRIDAY, EDITION th 9 2017

14:30-16:30 14:30-16:30 Presentation 1> Presentation 2> Presentation 2> Presentation 3> DAY 2

Scientific Programme and Daily Schedule DAY 2 DAY Presentation4> 14:30-15:30 15:50-16:30 15:10-15:50 14:30-15:10

2017 9 th th EDITION FRIDAY, 08DECEMBER2017 BMJ PublishersandRCPCH,London, UK Editor inChiefofBMJPaediatricsOpen, Ospedaliero-Universitaria Meyer, Florence Consultant PaediatricandLiverUnit Azienda Psychiatrist, GreatOrmondStreetHospital Consultant Childand Adolescent Paediatrics, UniversitairZiekenhuisBrussel Professor, HeadofDepartment Genetik, Wien Pathobiochemie, InstitutfürMedizinische Institut fürMedizinischeChemieund Zentrum fürPathobiochemieundGenetik, counseling, MedizinischeUniversitätWien, LSD metabolismscreeningandgenetic SUSANNE KIRCHER, Austria Spot theEarlySignsofMucopolysaccharidoses-OneDiseasewithManyFaces SES -MetabolicDisordersTraining 4 IMTI CHOONARA,UnitedKingdom Interactive Workshop PD3: WRITINGSCIENTIFICPAPERS GIUSEPPE INDOLFI,Italy Briefing withQ&A HEPATITIS C:Treatment ofHepatitisCVirus InfectioninChildren DASHA NICHOLLS,UnitedKingdom CHILD & ADOLESCENT MENTAL HEALTH: EarlyInterventionforEatingDisorders YVAN VANDENPLAS, Belgium Prebiotics andProbiotics- An Update for theGeneralPaediatrician BR1: PREBIOTICS&PROBIOTICS PROFESSIONAL DEVELOPMENT BRIEFING WORKSHOP 10: WORKSHOP 9: CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME | AFTERNOON SESSIONS • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: Understand howtochoosetherightjournal foryourpaper comments Understand howtorespondreviewer’s Understand howtoprepareapaperfor submission Have anoverviewoftherapeuticoptionsinthepipelinedevelopment Understand indicationsandcontraindicationstotreatment hepatitis Cvirusinfection Know thetreatmentoptionscurrentlyavailableforofchildrenwith chronic Differentiate earlyinterventionneedsbasedondiagnosisandrisk Explain theearlyinterventionapproachesinthispatientgroup disorders Understand theimportanceandsignificanceofearlyinterventionforoutcomeineating Understand theevidencebasedindicationofprobioticsintreatmentandprevention Understand thatnotallprobioticsproductsarecomparable in contentandmechanismsofactionpre-probiotics Understand thedifference betweenbreastfeedingand(unsupplemented)infantformula Consider possibleopportunitiesfortherapywhichdependonMPS-typeandage be done Recognize betterthedifferences ofthespecificfirstsymptomsandwhichtestsshould mucopolysaccharidosis Understand thepathophysiologyandrecognizedifferent typesof FRIDA Y , 08 DECEM , 08 B ER 2017 ER Wien Room Wien Room Wien Room Turin Room 39

Scientific Programme and Daily Schedule

40 ferently Turin Room Turin Mancini 2 Hall Mancini 1 Hall EIP Online EIP Also available through ER 2017 B , 08 DECEM Y FRIDA Review the dramatic changes in the understanding of cystic fibrosis and how this has translated into modern approaches Contrast progress in cystic fibrosis with the stagnation in other airway diseases, and bronchiolitis especially ‘asthma’ Understand how this may be remedied by the new approach to airway disease proposed by the Lancet commission on asthma Appreciate the factors that point towards pathology as opposed to physiology in the child Appreciate the factors that point towards pathology with polydipsia and polyuria piece of a much bigger jigsaw Understand why the water deprivation test is only one when attempting to make a diagnosis safely – doctors have Consider how best to manage cranial diabetes insipidus hyponatraemic traditionally been very good at rendering some patients and disorders of sex differentiation Understand the process of sex determination and development / atypical sex development (DSD) Review DSD where presentation is delayed until teenage or young adulthood and mainly characterized by atypical or incomplete signs of puberty Consider DSD diagnostic procedures in a patient who goes through puberty dif the hypothalamic-pituitary-adrenal axis Understand how topical glucocorticoids may affect potencies of the various topical glucocorticoid therapeutic agents Understand the differential Understand how the diagnosis of secondary adrenal insufficiency is made To appreciate to increasing role of social media in medical education and evidence appreciate to increasing role of social media in medical To based medicine highlight examples of good practice in paediatrics To of Social Media demonstrate the challenges To than the average child Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • Learning Objectives: • • • | AFTERNOON SESSIONS | ) Foyer & Mancini 3A DAILY PROGRAMME DAILY CONFERENCE PROGRAMME COFFEE BREAK ( PEDIATRICS PROFESSIONAL DEVELOPMENT PROFESSIONAL ANDREW BUSH, United Kingdom BR2: RESPIRATORY Airway Disease: Lessons from the Progress in Cystic Fibrosis Better Management of Paediatric Side Effects of Glucocorticoids with an Emphasis on Topical Administration Side Effects of Glucocorticoids with an Emphasis on Topical ALAN D. ROGOL, USA MARIA SZARRAS-CZAPNIK , Poland MARIA Abnormal Puberty as a First Symptom of Disorders/Differences of Sex Development (DSD) Abnormal Puberty as a First Symptom PE11: Section on ENDOCRINOLOGY PE11: Moderator: TIM CHEETHAM Learned Cranial Diabetes Insipidus – Lessons TIM CHEETHAM, United Kingdom PD4: SOCIAL MEDIA: KNOWLEDGE TRANSLATION IN THE 21ST CENTURY TRANSLATION MEDIA: KNOWLEDGE PD4: SOCIAL Interactive Workshop Kingdom DAMIAN ROLAND, United Professor of Paediatrics and Head of Section (Paediatrics), Imperial College,Professor of National Heart and Paediatric Respirology, Lung Institute University Reader and Consultant Paediatric Endocrinologist, Newcastle University, Hospitals NHS Tyne Newcastle upon Foundation Trust Professor Emeritus, Pediatrics and University of Virginia Pharmacology, Consultant and Honorary Associate Consultant and Honorary Medicine, Professor in Paediatric Emergency Leicester University of Leicester and Hospitals The Children’s Consultant Endocrinologist, Memorial Health Institute, Warsaw BRIEFING FRIDAY, 08 DECEMBER 2017 08 DECEMBER FRIDAY, EDITION th 9 2017

16:30-17:00 17:00-18:30 15:30-16:30 17:00-17:45 Presentation 2> Presentation 3> Presentation 1> DAY 2

Scientific Programme and Daily Schedule DAY 2 DAY 17:00-18:30 17:45-18:30 17:00-18:30 17:00-18:00

18:30 2017 9 th th EDITION FRIDAY, 08DECEMBER2017 • • • DAY CLOSING PROFESSIONAL DEVELOPMENT BRIEFING Department, Bucharest Alessandrescu-Rusescu, Pediatrics Medical GeneticsBucharest,INSMC Clinical Geneticist,RegionalCenterof Antwerpen and Immunology, PaolaChildrensHospital, Professor ofPediatricHematology, Oncology • • Learning Objectives: Chief ExecutiveoftheLeadershipFoundationforHigherEducation ALISON JOHNS,UnitedKingdom BOSCH, Belgium JUTTE VAN DERWERFF TEN How toRecognisePrimaryImmunodeficiencies BR3: PRIMARY IMMUNODEFICIENCIES VASILICA PLAIASU,Romania Case StudiesinClinicalGenetics:HintsandPitfallsforUndiagnosedL SES -MetabolicDisordersTraining 5 Moderator: UMA RAMASWAMI SES2: SPOTTHEEARLY SIGNS Interactive Workshop PD5: PRESENTATION SKILLSFORHEALTHCARE PROFESSIONALS OP5: ORAL PRESENTATIONS SPOT THEEARLY SIGNS Begin andendapresentationwithimpactauthority Manage nervousnessandothernegativepre-presentationfeelings Communicate aclearmessage,projectenthusiasmandmaintaininterest Define thepurposeandobjectivesofapresentation,anticipateneedsaudiencedevelopsimpleef Speak togroupswithconfidence,professionalismandcommitment CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME | AFTERNOON SESSIONS Moderator: JOAN-CARLESSURIS • • • Learning Objectives: • • • • Learning Objectives: genetic counsellingissues disease progression,genotype/phenotypecorrelation,familyhistoryandpedigree, in ageofpresentation,broadheterogeneityclinicalpresentations,variable rateof Provide commonandparticularLSDswithexamplesofpitfallsintermsvariability imaging, biochemical,molecular)withimportanthints Describe diagnosticproceduresandlaboratorytestsusedtodiagnoseLSDs (clinical, An overviewofvariousclassificationsLSDs What canIdomyselftostartthework-up How torecognizeanImmunologicalemergency How torecognizeachildwithanimmunodeficiency A practicalandveryshortrecapitulation ofthefunctionimmunesystem Programme Director, LeadershipFoundationforHigherEducation DOUG PARKIN, UnitedKingdom FRIDA Y , 08 DECEM , 08 ysosomal StorageDisorders B ER 2017 ER Mancini 3BHall Education Program Spot theEarlySigns Early diagnosiscanmake adifference. fective structure Mancini 1Hall Wien Room Turin Room 41 Metabolic Diseases

Scientific Programme and Daily Schedule Harvey Goodwin Hall

42 health, ferences in

Mancini 1 Hall Mancini 2 Hall alue Globally ER 2017 Austria B EIP Online EIP Also available through , 9 DECEM Y SATURDA | MORNING SESSIONS | MORNING life satisfaction and health behaviours Consider the role of family communication and support as a protective factor against engaging in risk behaviours: smoking, drinking, using cannabis, early sexual or suicidal behaviours and self-harm Describe the family social context; Growing up unequal: socioeconomic dif health and well-being. young people’s Explore the association of parental communication and support with adolescents’ What is PHDU care (Paediatric Critical Care Levels 1 & 11)? How to develop and sustain 1 & 11)? What is PHDU care (Paediatric Critical Care Levels quality of care in a PHDU? and health economic value? Who should be cared for in a PHDU and the clinical in acute care of infants and children Regional and National models of PHDU and the role globally Understand the importance of parental mental ill health as a risk factor for adolescent mental ill health and the various pathways through which the former influences the latter Review existing support and prevention programmes for young people caring for a parent with mental ill health, including practice examples from Understand the concept of rational prescribing Be aware of examples of irrational prescribing children Be aware of tools to assess rational prescribing in Review recent evidence on decision making in medicine decision making in acute paediatrics Understand how cognitive processes affect making in students and junior Review how we can optimise training to improve decision health professionals Discuss what professionals (pediatrists, GP’s, nurses,..) can do to “detect” and support Discuss what professionals (pediatrists, GP’s, adolescent carers for a parent with mental ill health • • Learning Objectives: • Learning Objectives: • • • Learning Objectives: • • Learning Objectives: • • • Learning Objectives: • • • • DAILY PROGRAMME DAILY CONFERENCE PROGRAMME COFFEE START (Foyer & Mancini 3A) COFFEE START The Family as a Protective Health Asset for Adolescents’ Development: Insights from the Adolescents’ Asset for The Family as a Protective Health HBSC Study ELLEN KLEMERA, United Kingdom AAGJE IEVEN, Belgium LADURNER JOY HPE Austria AD4: Section on IMPROVING FAMILY HEALTH AD4: Section on IMPROVING FAMILY with Caregiving Responsibilities and Their People Young Adolescent Mental Health: Supporting Families ROY K. PHILIP, Ireland K. PHILIP, ROY DAMIAN ROLAND, United Kingdom Associate Professor Consultant and Honorary in Paediatric Emergency Medicine, University of Leicester and Leicester Hospitals Critical Care Levels I & II): Role and V Paediatric High Dependency Care (Paediatric IMTI CHOONARA, United Kingdom Staff Effectively? Are we Training Decision Making in Paediatric Care: PE12: Section on CLINICAL PRACTICE CLINICAL PE12: Section on Moderator: TERENCE STEPHENSON When Prescribing? Rationally? What Should be Considered Do we use Medicines Senior Research Fellow in Adolescent, Senior Research Fellow in University of Team, Child and Family Health Hertfordshire, HBSC England Consultant Paediatrician and Neonatologist, Adjunct Clinical Professor of Neonatology, University Maternity Hospital Limerick & GEMS, University of Limerick, IRELAND Emeritus Professor in Child Health, Academic Division of Child Health (University The Medical School, of Nottingham), Hospital Derbyshire Children’s ADOLESCENT MEDICINE PEDIATRICS Secretary General, EUFAMI SATURDAY, 9 DECEMBER 2017 9 SATURDAY, EDITION th 9 2017

09:30-11:30 09:30-11:30 08:30-09:30 Presentation 2> Presentation 2> Presentation 1> Presentation 3> Presentation 1> DAY 3

Scientific Programme and Daily Schedule DAY 3 DAY 09:00-11:30 09:30-11:30

2017 9 th th EDITION SATURDAY, 9DECEMBER2017 Essentials ofInvasiveandNon-invasiveVentilation inNewborns PART 4Essentialsofsurfactanttreatmentandnitricoxide(NO) PART 3Essentialsofnon-invasiveventilation PART 2Essentialsofinvasiveventilation(incl.HFOV) PART 1EssentialsofCPAP andHighflow-nasalcannula Department Pediatrics,UniversityHospitalFreiburg Professor, IntensiveCareat Head of Division Neonatology/Pediatric ROLAND HENTSCHEL,Germany Audience ResponseSession-Coffeeservedinroomfrom10:00-10:30 MC1: NEONATOLOGY MASTERCLASS for HigherEducation Programme Director, LeadershipFoundation DOUG PARKIN, UnitedKingdom Foundation forHigherEducation Chief ExecutiveoftheLeadership ALISON JOHNS,UnitedKingdom Leading ChangeinaComplexEnvironment Interactive Workshop PD6: LEADINGCHANGEIN A COMPLEXENVIRONMENT • • • • • • • • • • • • Learning Objectives: PROFESSIONAL DEVELOPMENT Consider SurfactantandiNOasprophylactictherapeuticaidindifferent respiratorydiseases Review thecurativepotentialofSurfactantandiNOtreatmentasanadjuncttomechanicalventilationinrespiratorydiseasesnewborn Understand thephysiologicalbasisandsignificanceofSurfactantiNOtreatmentinneonatalintensivecaremedicine ESSENTIALS OFSURFACTANT TREATMENT AND NITRICOXIDE(iNO) Consider benefitsandcomplicationsofNIPPV Review indicationsforNIPPVindifferent clinicalsettingsbasedonstudyresults Understand anddefinebasicprinciplesofnoninvasivepositivepressureventilationinneonates ESSENTIALS OFNON-INVASIVE VENTILATION Consider HFOVorconventionalmechanicalventilationasdifferential approachesforventilatorysupport Review individualpatientsfortheirneedsofactualventilationsupportatdifferent stagesofdisease Understand modernconceptsofneonatalventilationbasedonpatient-triggeredvolume-adoptedlung-protectivestrategies ESSENTIALS OFINVASIVE VENTILATION (incl.HFOV) Consider advantagesandlimitationsofbothformsneonatalrespiratorysupport Identify patientswhoareselectedfororexcludedfromtheuseofCPAP andhigh-flownasalcannulaindailypracticeNICU Understand anddefinethemodeofactionCPAP andhigh-flownasalcannulabasedonphysiologicalprinciples ESSENTIALS OFCPAP AND HIGH-FLOWNASAL CANNULA CONFERENCE PROGRAMME CONFERENCE DAILY PROGRAMME • • • • Learning Objectives: And whatistherelationshipbetweenculture,strategyandchange? with this? What doweunderstandbyuser-centeredchangeandwhatarethevaluesassociated How canyouinspirecollectivecommitmentaroundtheneedforchange? What arethedriversforchangesurroundingcontextinwhichyoulead? |MORNINGSESSIONS Salzburg in PediatricsatLMUUniversityMunichandParacelsus Head ofDepartmentPediatrics,KlinikumRosenheim&Lecturer TORSTEN UHLIG,Germany, Austria SATURDA Y , 9DECEM B ER 2017 ER Mancini 3BHall Wien Room 43

Scientific Programme and Daily Schedule 44 , UK Turin Room Turin ER 2017 B , 9 DECEM Y SATURDA ferent ways of answering areas of clinical uncertainty | MORNING SESSIONS | MORNING Understand the differences in emphasis needed when writing CVs for different positions writing CVs for different in emphasis needed when Understand the differences research posts such as clinical and academic needed for writing successful grant applications and strategies Realise the different publishable papers responses so as to maximise Structure a scientific paper and deal with reviewers chances of ultimate acceptance Learning Objectives: • • • (Mancini 2 Hall) JO INCHLEY TERENCE STEPHENSON, JOAN-CARLES SURIS, DAILY PROGRAMME DAILY CONFERENCE PROGRAMME The first objective is for you to consider whether you should change your practice too in the light of these? The first objective is for you to consider whether you familiar with the dif The second objective is to consider whether you are The third objective is to consider whether you can critically assess the papers which you read and the talks which you hear The third objective is to consider whether you can CONFERENCE CLOSING REMARKS PROFESSIONAL DEVELOPMENT PROFESSIONAL PD7: PROFESSIONAL DEVELOPMENT CVs, GRANTS & PAPERS DEVELOPMENT CVs, GRANTS PD7: PROFESSIONAL Session Audience Response Kingdom ANDREW BUSH, United PLENARY CLOSING LECTURE PLENARY Five Papers Which Changed My Practice CONFERENCE CHAIRS: TERENCE STEPHENSON, United Kingdom Health, UCL, Chair General Medical Council (UK) 2015-2018, Former Chair Nuffield Professor of Child Health, Institute of Child Academy of Medical Royal Colleges 2012-2014, Past President, Royal College of Paediatrics and Child Health 2009-2012 Academy of Medical Royal Colleges 2012-2014, Past Learning Objectives: • • Professor of Paediatrics and Head of Section Professor of Paediatrics and (Paediatrics), Imperial College, Professor of National Heart and Paediatric Respirology, Lung Institute • Academic Survival: How to Write Your CV, Grant Applications and Papers Applications Grant CV, Your How to Write Academic Survival: SATURDAY, 9 DECEMBER 2017 9 SATURDAY, EDITION th 9 2017

09:30-11:00 11:30-12:00 12:00-12:30 DAY 3

Scientific Programme and Daily Schedule CONFERENCE PROGRAMME 2017 SCIENTIFIC PROGRAMME AND DAILY SCHEDULE 45 9th EDITION

FROM THE LEADERSHIP FOUNDATION FOR HIGHER EDUCATION

Turin Room FRIDAY 8th DEC PROFESSIONAL DEVELOPMENT 09:00-11:00 Workshop: Discovering Leadership - to engage, develop and transform Interactive Session

Module 1 - Leadership and Team Development

There is nothing greater than great leadership, not for what it is in itself but for what it enables others to achieve, create and become. This session will be an opportunity to develop your understanding of leadership, particularly team leadership and team development. It will encourage you to consider afresh the question “what sort of leader do I want to be?” and to explore this through some contemporary perspectives such as transformational leadership and collective leadership. Within this we will consider the characteristics of high-performing teams and the leader’s role in supporting teams to develop and flourish. This session will explore: — What sort of leader do you want to be? — What are your strengths, passions, blind spots and aspirations for development? — What are the characteristics of both high performing and dysfunctional teams? — And how can you promote and empower collaborative teamwork?

Facilitators: ALISON JOHNS, United Kingdom Chief Executive of the Leadership Foundation for Higher Education ScientificProgramme and Daily Schedule DOUG PARKIN, United Kingdom Programme Director of the Leadership Foundation for Higher Education

Wien Room FRIDAY 8th DEC PROFESSIONAL DEVELOPMENT 17:00-18:30 Workshop: Presentation Skills for Healthcare Professionals. You can lecture an audience to knowledge (sometimes), but you must inspire it to think!

This highly engaging and practical session will help you to speak so that others want to listen and to prepare and deliver presentations that get your message across with energy and confidence. Whether presenting to a large audience, sitting around a table or to a group of colleagues, the ideas and techniques covered in this session will help you to use these opportunities to make a powerful and memorable impact. This session will explore how to: — Speak to groups with confidence, professionalism and commitment — Define the purpose and objectives of a presentation, anticipate the needs of the audience, and develop a simple and effective structure — Communicate a clear message, project enthusiasm and maintain interest — Manage nervousness and other negative pre-presentation feelings — Begin and end a presentation with impact and authority.

Facilitators: ALISON JOHNS, United Kingdom Chief Executive of the Leadership Foundation for Higher Education DOUG PARKIN, United Kingdom Programme Director of the Leadership Foundation for Higher Education CONFERENCE PROGRAMME 2017 SCIENTIFIC PROGRAMME AND DAILY SCHEDULE 46 9th EDITION

Wien Hall SATURDAY 9th DEC PROFESSIONAL DEVELOPMENT 09:30-11:30 Workshop: Discovering Leadership - to engage, develop and transform Interactive Session

Module 2 - Leading Change in a Complex Environment

“Today, the most important question for any organization is this: are we changing as fast as the world around us?” (Gary Hamel, 2012, What Matters Now). Gary Hamel’s insightful quote is as important for healthcare organisations as for any other large public or corporate organisation. And where there is high complexity, whether arising from user needs, service enhancement and diversification, or external expectations the uncertainties about change become magnified. This session will be an opportunity to explore the drivers for change that are most critical in your context and their implications for you as a leader. It will also stimulate discussion and ideas about creating collective commitment around the need for change and building a sense of shared purpose and mutual accountability. Scientific Programme and Daily Schedule Daily and Programme Scientific This session will explore: — What are the drivers for change surrounding the context in which you lead? — How can you inspire collective commitment around the need for change? — What do we understand by user-centred change and what are the values associated with this? — And what is the relationship between culture, strategy and change?

Facilitators: ALISON JOHNS, United Kingdom Chief Executive of the Leadership Foundation for Higher Education DOUG PARKIN, United Kingdom Programme Director of the Leadership Foundation for Higher Education CONFERENCE PROGRAMME 2017 SCIENTIFIC PROGRAMME AND DAILY SCHEDULE 47 9th EDITION

2ND LIFECOURSE IMMUNISATION FOCUS GROUP - INCREASING VACCINATION RATES ACROSS EUROPE

The 2nd Life Course Immunisation Focus Group

After the very successful 2016 Life Course Immunisation Focus Group at the Excellence in Paediatrics Conference in London, EIP are once again collaboration with the Confederation of Meningitis Organisations (CoMO), the Coalition for Life Course Immunisation (CLCI) and a host of partners for the 2nd Life Course Immunisation Focus Group.

The 2nd Life Course Immunisation Focus Group is taking place on Friday 8th December 2017 in the Wien Room from 10:15-14:15 and is tasked with aligning strategies to increase vaccination rates and overcome vaccine hesitancy across Europe. The meeting puts you as a frontline HCP at the centre of immunisation strategy. This is an open meeting and we would encourage you to join to help improve vaccinations rates across Europe.

Date & Time Friday 8th December 2017, 10:15 - 14:15 (coffee/lunch provided in the room)

Location Hotel Savoyen, Vienna, Austria

Room During EIP Conference, Wien Hall

The Agenda of the meeting is detailed below and we look forward to welcoming you on Friday 8th December.

Section Section Type/Time Section Title Section Overview, Scope & Speakers

Introduction to the Focus Group from the Chairs - Purpose of ScientificProgramme and Daily Schedule 10:15-10:30 Welcome meeting, structure, desired outcomes - Introduction to Co-Chairs - Terence Stephenson, Daphne Holt & David Salisbury.

An overview of current vaccines policies across Europe (Updates Setting the Scene - from the European Commission, and Countries). Examining Overview of Vaccines changes made and positive steps taken on vaccination policies POLICY Policies, Changes across Europe (and within European countries) during 2017. Made and Steps Taken Outlining Vaccination priorities in 2018, reviewing surveillance data in the last 12 months and current population coverage. Section Chaired by: Prof David Salisbury

Surveillance & Population Coverage Across Europe 10:30-10:45 Overview Speaker: Pier Luigi Lopalco (via video link)

Vaccination Update – policies, progress and priorities in Spain 10:45-11:00 Spain Part 1 - Speaker: Francisco Gimenez Sanchez 10:15 -12:15 - Vaccination Update - policies, progress and priorities in the Coffee Served 11:00 -11:15 The Netherlands Netherlands Speaker: Elisabeth Sanders in Room Communication and information dissemination during a pandemic 11:15 -11:30 Ireland Results and experiences from the 2016 Irish Citizen Consultation Speakers: Peggy Maguire/Vanessa Moore

Vaccination Update - policies, progress and priorities in Greece 11:30 -11:45 Greece Speaker: George Syrogiannopoulos

Update on progress and Joint Action 11:45 -12:00 European Commission Speaker: Michael Sulzner

• Reviewing the changes made in individual countries and within the decision-making bodies of the European Union. • Policy changes mapping for European countries present 12:00 - 12:15 Open Forum • Group will conclude if during the last year positive changes have been made towards the target of universal immunity against vaccine preventable diseases. CONFERENCE PROGRAMME 2017 SCIENTIFIC PROGRAMME AND DAILY SCHEDULE 48 9th EDITION

Introducing the Coordination and alignment of the planned actions of CLCI PLANNED Coalition for Life members and all stakeholders involved in the promotions of ACTIONS Course Immunisation vaccinations across Europe. Section Chaired by: Daphne Holt (CLCI)

• Part 2 Overview from the Coalition for Life Course Immunisation (CLCI) business meeting held 12:15 - 13:00 earlier in the day – Malcolm Taylor – 10 minutes • Selected presentations from CLCI members to hear about activities that individual 12:15 -13:00 members are already planning/implementing – 4 x 7 minutes – 28 minutes in total

• Networking and working for a common cause - examining overlaps and combined actions to create greater outreach – Gertraud Daye – 10 minutes

Break 13:00-13:10 Break and Lunch Served (Please return to assigned Focus Groups for Working Lunch)

Scientific Programme and Daily Schedule Daily and Programme Scientific Introduction to focus groups, procedures, outcomes and reporting Intro to Part 3 13:10-13:15 Section Chaired by: Terence Stephenson

13:15-13:50 Focus Group A

Improving the What should be done to improve advocacy of vaccines by HCPs Working Group Advocacy of both to the families they support and to their colleagues? on Advocacy all Healthcare Led by EiP Professionals

Part 3 13:15-13:50 Focus Group B 13:10 -13:50 - What should be done to overcome vaccine hesitancy? Strategies to Working Group on Overcoming Vaccine Lunch served, deal with the anti-vaccine lobby, firefighting or proactivity Vaccine Hesitancy Hesitancy but as part of a Led by EIWH working lunch 13:15-13:50 Focus Group C

Working Group Designing a Europe-wide life course immunization strategy – blue on a Europe- A Europe-wide life sky thinking. What would it look like, what are the criteria, what are wide Life Course course immunization the economics? Is it feasible and desirable at this point in time? Immunization strategy Led by CLCI Strategy

Conclusions Outlining of Ideas and Future Actions and Close Part 4 13:50 - 14:15 13:50-14:05 Spokesperson for each Focus Group to report back to Group

14:05-14:15 Co-Chairs' Summary and Close CONFERENCE PROGRAMME ABSTRACT BOOK Abstracts 50

ABSTRACTS CONFERENCE PROGRAMME CONFERENCE

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Rue des Vignerons 1B, Case Postale 359, 1110 Morges 1 (VD), Switzerland 359, 1110 1B, Case Postale Rue des Vignerons Consultant Paediatrician and Allergist, University College London Hospital, UK Consultant Paediatrician and George Syrogiannopoulos School of Medicine in Thessaly, Professor and Chairman of Paediatrics at the University of Larissa, Greece Bosch Ten Jutte van der Werff Paola Childrens Hospital, Oncology and Immunology, Professor of Pediatric Hematology, Antwerpen, Belgium Excellence in Pediatrics Institute Consultant and Honorary Associate Professor in Paediatric Emergency Medicine, University Consultant and Honorary of Leicester and Leicester Hospitals, UK Bob Sallis Clinical Professor of Family Medicine, UC Riverside School of Medicine, USA, Co-Director, Exercise is Medicine, USA Sports Medicine Fellowship, Kaiser Permanente, Chair, Penny Salt Consultant Paediatrician and Neonatologist, Adjunct Clinical Professor of Neonatology, Adjunct Clinical Professor of Neonatology, Consultant Paediatrician and Neonatologist, University Maternity Hospital Limerick & GEMS, University of Limerick, Ireland Alan D. Rogol USA University of Virginia, Professor Emeritus, Pediatrics and Pharmacology, Damian Roland Imperial and UniversityConsultant Paediatrician, Royal National OrthopaedicsHospitals, College, UK Francesc Palau (IPER) and Head of the GeneticsDirector of the Institute for Pediatric Rare Diseases Research Professor and Visiting Hospital. CSIC Department, Sant Joan de Déu Children’s SPAIN Professor Pediatrics, University of Barcelona, Roy K. Philip Consultant in General Paediatrics and Paediatric Allergy, University College London Allergy, Consultant in General Paediatrics and Paediatric Hospital, UK Dirk van Gysel and formerAalst. Board member Hospital Vrouw Head of the Department of Pediatrics, O.L ESPD, Belgium of the Treasurer Kenneth J. Mack Neurology, Adolescent Mayo Clinic, Child and Neurology Society, President Child Professor, USA Colin Michie Professor, Consultant Paediatric Gastroenterologist, University Hospital Southampton, UK Consultant Paediatric Professor, Alberto Borraccino and Torino Department of Public Health and Paediatrics, University of Assistant Professor, HBSC Italy Michael Fitzgerald Ireland Adolescent Psychiatry, Professor of Child and Leanne Goh Abstracts Reviewers Abstracts Aleman-Diaz Y Aixa Adolescent Health Child and WHO Collaborative Centre for International Advisor, Policy UK and HBSC ScotlandAndrews, of St University Policy, Mark Beattie ABSTRACTS

Scientific Programme and Daily Schedule ABSTRACTS TECHNOLOGY ORAL PRESENTATIONS antibiotics during pregnancy and lactation. Previous studies showed that risks related to the presence of antimicrobials in food are multiple multiple are food in antimicrobials of presence the to related risks that showed studies Previous lactation. and pregnancy during antibiotics habits. dietary maternal the with associated not was milk human in quinolones or lactams beta of presence The after. 12 and positive beta-lactams for (85.5%) positive were samples milk human 83 of 71 out delivery. after 7days maximum treatment, antibiotic area and low birth weight, associated with wasted children. wasted with associated weight, birth low and area analysis. multivariate with continue and significance the determine to test exact Fischer or Chi-Square the using analysis complete to task easy an not is It persons. older and woman, lactating and pregnant, girls, adolescent of needs nutritional the address and age end all form of malnutrition including achieving by 2025 the internationally agreed targets on stunting and wasting children under five years of of years five under children wasting and stunting on targets agreed internationally the 2025 by achieving including malnutrition of form all end 2030 by is target the of one which agriculture sustainable promote and nutrition improved and security, food achieve hunger, (SDGs) end to Presentations questionnaires previously validated, including sociodemographic data, characteristic of mother and children, infant feeding practice data. data. practice feeding infant children, and mother of characteristic data, sociodemographic including validated, previously questionnaires goals development sustainable achieve to agenda aworld is It malnutrition. and hunger by caused is year per death 5million over claims 1 samples for polymyxine, one sample for sulfonamide, two positive samples for tobramycine have been noted. There are no differences differences no are There noted. been have tobramycine for samples positive two sulfonamide, for sample one polymyxine, for samples 4positive cefuroxime, for samples 5positive basitrasin, for 2positive (14.5%). amphenicol, for quinolones for samples Twosamples positive study. this supported has Grant Research University Osmangazi Eskisehir The toxins. some and residues CHILDREN UNDERFIVE YEARS OLDINGORONTALO RURAL AREA 2016 Presentation Oral association investigate and years five under children to feeding complement nutritious and breastfeeding, exclusive and initiation early as such Presentation Oral Investigator™ system (Randox, UK), which is a multi-array biochip, semi- automated system, designed for research for evaluation of antibiotic antibiotic of evaluation for research for designed system, automated semi- biochip, amulti-array is which UK), (Randox, system Investigator™ multivariate analysis p 0.00 (OR 15.58 CI95% 2.00 – 121.32). it is also statistically significant relationship between complementary feeding feeding complementary between relationship significant –121.32). 2.00 statistically (OR 15.58 CI95% p0.00 also is it analysis multivariate SCREENING OF30 ANTIBIOTIC RESIDUESINHUMANMILKWITHMULTI-RESIDUE METHODBASEDONCHIP Conclusions: status. nutritional child with Conclusion: received have and mothers 18 cephalosporin) generation (first prophylaxis antibiotic dose one received been have 31 mothers C-section, prophylaxis with cefazoline sodium during labor has been noted. Human milk antibiotic residues have been evaluated with the Evidence Evidence the with evaluated been have residues antibiotic milk Human noted. been has labor during sodium cefazoline with prophylaxis practice and nutritional status p 0.00 (OR 6.52, CI95% 1.76--24,14) and in multivariate analysis p 0.02 (OR 4.76, p0.02 1.24-18,23). CI95% 1.76--24,14) CI95% analysis (OR 6.52, p0.00 status multivariate in and nutritional and practice Faculty of Medicine, Department of Pediatric Neurology, Turkey; Neurology, [email protected] Pediatric of Department Medicine, of Faculty Paguyaman Primary Health Care; [email protected] Health Primary Paguyaman Results: old days 7-90 have who mothers from taken samples milk human in residues antibiotic of levels the study to planned we study, this In Purpose: milk. human in levels residue antibiotic milk human the about information no is there knowledge, literature baby. our of Tothe best the Results: practice feeding infant of implementation the and children, and mothers of characteristic investigate to is study the of objectives The Purpose: to needed is status nutritional with associated factors other and practice feeding infant analysing Therefore, prevalence. wasted high has that Ruslyaraz Hospital, Turkey; Hospital, Nutritional status has been plotted using WHO 2006 and PRIMA devices. Analysis was done by univariate analysis for descriptive and bivariate bivariate and descriptive for analysis univariate by done was Analysis devices. PRIMA and 2006 WHO using plotted been has status Nutritional FatimahSania Methods: Meltem Dinleyici Meltem Methods: INAPPROPRIATE INFANT FEEDINGPRACTICE AND LOWBIRTHWEIGHT ASSOCIATED WITHNUTRITIONAL STATUS Introduction: ID: 178 /OP1:ID: 2 Introduction: /OP1: 154 ID: 1 between the positive antibiotic residues (for beta-lactams and quinolones) between mother received or not received antibiotics during labor and and labor during antibiotics received not or received mother between quinolones) and beta-lactams (for residues antibiotic positive the between Turkey. in babies, be evaluated. be Indonesia in cities the of one is Gorontalo Indonesia. like country developing in especially, evaluation, goals development Millennium on based █ Eskisehir Osmangazi University Faculty of Medicine, Department of Social Pediatrics, Turkey; Pediatrics, Social of Department Medicine, of Faculty University Osmangazi Eskisehir █ Time: OP1: PRESENTATIONS: ORAL 1 SESSION 83 mothers aged between 17 to 41 years (mean age 29.7 ± 6.2 years), have been enrolled. 56.6% of pregnant women have been been have women pregnant of 56.6% 17 enrolled. years), 29.7 been have 41 to ±6.2 age (mean between years aged mothers 83 There is a statistically significant relationship between low birth weight and wasted p 0.03 (OR 5.33, CI 95% CI 5.33, 1.08—26.11) (OR p 0.03 wasted and weight in birth and low between relationship significant astatistically is There Pregnant women who have been received antibiotic treatment during pregnancy were excluded. The presence of antibiotic antibiotic of presence The excluded. were pregnancy during treatment antibiotic received been have who women Pregnant An observational analytic cross sectional design was used to mothers of 6 – 59 month children. It is 92 extracted data data extracted 92 is It children. month 6–59 of mothers to used was design sectional cross analytic observational An 20 9 Thursday, 07/Dec/2017: 11:00am - 1:00pm • Location: Turin Hall •Location: -1:00pm 11:00am 07/Dec/2017: Thursday, t h We found that majority of human milk samples includes beta-lactams or quinolones, while mothers did not receive these these receive not did mothers while quinolones, or beta-lactams includes samples milk human of majority that We found

E It is important to identify as well as other undesirable toxins and metabolites that may be present in the human milk and pass to to pass and milk human the in present be may that metabolites and toxins undesirable other as well as identify to important is It Malnutrition is a significant factor associated with more than half children mortality in the world. Food agricultural organization organization agricultural Food world. the in mortality children half than more with associated factor asignificant is Malnutrition Inappropriate infant feeding practices, in this case an introduction to complementary feeding after 6 month in Gorontalo Rural Rural Gorontalo in 6month after feeding complementary to introduction an case this in practices, feeding infant Inappropriate D I T 1 , I O Yun Istatik, Istatik, Yun 7 3 1 Eskisehir Osmangazi University Faculty of Medicine, Division of Neonatology, Turkey; Neonatology, of Division Medicine, of Faculty University Osmangazi Eskisehir N , Gonca Kilic Yildirim Kilic , Gonca Topics: Topics: Nutrition & Diets, Neonatal Nutrition Neonatal &Diets, Nutrition &Diets Nutrition Pediatrics, General Ikhwanuliman Putera, Putera, Ikhwanuliman CONFERENCE PROGRAMME ABSTRACTS 2 , Ozge Aydemir , Ozge Dwi Mulia, Mulia, Dwi 3 , Tugba Barsan Kaya , Tugba Barsan

VaniaTryanni, 2 , Yasar Bildirici , Yasar Daeng Fachrianzy, Daeng ORAL PRESENTATIONSORAL 2 Eskisehir Maternity and Children Children and Maternity Eskisehir 2 , Kursat Bora Carman Bora , Kursat 4 SyandriagusRizky, Eskisehir Osmangazi University University Osmangazi Eskisehir ISSN 2297-9360 4 Ruslyaraz 51

Abstracts , 5 52 U.O. 7 , Massimo Agosti Massimo , 4 Servicio de Pediatria- 3 , Antonio Muñoz Antonio , 3 Azienda Ospedaliera - Polo Universitario 5 ORAL PRESENTATIONS ,Rocio Porcel 2 ,Kelly A Mulder

Jefe de Servicio de Pediatría, Hospital Universitario Reina Sofia, 2 8 8 Danone Nutricia Research, Utrecht, The Netherlands; 2 HettyBouritius , 2 , Juan Navero L. P. 7 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE Hospital Clinico Universitario San Cecilio, Granada, Spain; 4 , Thomas Ludwig Thomas , 1 Nutrition & Diets, Allergy, Immunology & Pulmonology General Pediatrics, Gastroenterology & Metabolism SC Neonatologia Intensiva – Terapia Neonatale, Istituti Clinici di Perfezionamento, Milan, Italy; 6 Topics: Topics: N 7 O I , Luigi Tommaso Corvaglia , Angelo Pietrobelli, Giulia Paiola,Giorgio Piacentini, Laura Tenero 1 T 6 I D 3 specific components of wheat have importance in wheat allergy:γ, ώ isoforms), a gliadin gliadin a β, Lipid(α, 19), subunit a (Tri A partly fermented (LactofidusTM process) infant formula(IF) combined with short-chain galacto-oligosaccharides(scGOS) and E

In this study, investigators reported fewer cases of infantile colic in infants AEs) (as receiving a partly fermented IF combined Wheat allergy belongs to the group of gluten-related immune disorders, which also includes celiac disease and gluten sensitivity. h t 9 20 investigators reported infantile colic less compared frequently to the in the control active (P=0.020, group group (8.7%) (1.1%) Fisher’s OP1: ORAL PRESENTATIONS: SESSION 1 ORAL PRESENTATIONS: OP1: Instituto Hispalense d Pediatria Seville, (IHP), Spain; Introduction: ID: 290 3 / OP1: Introduction: / OP1: 4 ID: / OP1: 218 infant). Given the different pathogenesis, in the context of wheat allergy and the riskof anaphylaxis, it is important to have a proper diagnostic introduced to the formula after one week of age. long-chain fructo-oligosaccharides (lcFOS) has previously been reported to reduce infantile colic (derived from parent-reported crying duration) INVESTIGATOR-REPORTED INFANTILE COLIC IN HEALTHY TERM-BORN INFANTS COLIC IN HEALTHY INFANTILE INVESTIGATOR-REPORTED Materials and Methods: Healthy IF fed infants aged ≤ 28 days (n=200) were randomised to receive an IF combining 30% of a fermented Neonatal Intensive Care Unit, University Hospital, Bologna, Italy; Luca Pecoraro tests have little specificity. It is necessary to use the determination of sIgE against wheat allergen(RAST) and its components(ImmunoCAP), Hospital Quiron, Barcelona, Spain; the described symptomatology, skin and laboratory tests and resolution of symptoms after wheat-free diet, the pathogenesis can be referred to to mediated IgE reactions are seen about hours 1-2 after the introduction of the food) and the early age of onset of symptoms (the patient is an Results: Purpose: In this new randomised controlled trial, we further investigated in detail the effect of an IF combining a partly fermented IF with formula (derived from an unique fermentation process, LactofidusTM) with scGOS/lcFOS(active) or a (0.8g/100ml,non-fermented 9:1) IF framework, which leads to appropriate therapy, represented by the use of a wheat protein-free diet and adrenaline (when needed) with a plan of 2.2), and 0.9 (0.4-1.8) h/d at 5 weeks of and age2.2), for 0.9 (0.4-1.8) the active, control, and breastfed groups, respectively. Preliminary post hoc analyses revealed that F. Del Ponte, Varese, Italy; F. pregnancy and lactation are needed. GianlucaLista which have low specificity but a high diagnostic sensitivity.Positivity of a single molecular component is required to diagnose wheat allergy. Case Report: S. is a 6-month-old infantwithout noteworthy anamnestic elements. 2 hours after the introduction of the semolina, onset of Córdoba, Spain; [email protected] Córdoba,Spain; wheat and ImmunoCap for wheat components: kUA/L. 3.69 sIgE: kUa/L; 2,33 kUA/L; a 14: gliadin: 0.10 Tri 0.36 a 19 kUa /L; Tri Conclusion: wheat allergy; specifically(3, 14 69 Tri a kAa / l) and gliadin(0.36 kUaDifferential / l). diagnosis should be made with(Food FPIES protein-induced urticaria, edema ofthe ear pads, repeated vomiting, with spontaneous resolution. Subsequently, food prick tests were performed with positive without scGOS/lcFOS (control) weeks until of age. An 17 exclusively breastfed reference was also group included. (n=100) The incidence of Conclusion: with scGOS/lcFOS. Additional analyses of daily crying duration also demonstrated a lower incidence of excessive crying in infants that were reactions, not at risk of anaphylaxis. In the suspect of wheat allergy, skin prick tests and prick-by-prick represent first-level tests; both however, response only for wheat. Prick by prick with semolina was negative. After a month of weaning with diet excluding the food, a new dose of University of Verona, Pediatrics, Italy; [email protected] Oral Presentation received human milk with or without antibiotic residues. Further strategies including the food safety and appropriate antibiotic use policy during IF. The interventionIF. effect was not significantly different in the group of infants that started on study product before one week of age. semolina was given: after 4 hours after intake, pallor, asthenia, in association, repeated vomiting, resolved about 1 hour after the onset of the symptoms. Afterwards, he continued weaning and diet without grain and derivatives, withoutclinical symptoms. the At RAST age for of 1 year, significant difference between study product groups(P>0.05, Mann-Whitney with U test), the highest1.3(0.5- 1.3 (0.5-2.3),median (Q1-Q3) of scGOS/lcFOS on gastrointestinal related (GI) parameters collected daily throughout the intervention period. Oral Presentation 1 of the gliadin are associated wheat a 19 and Tri with severe allergic reactions and risk of anaphylaxis; is implicated a 14 Tri in mild allergic on early maintenance of intestinal microbiota composition. plan We to perform intestinal microbiota composition of newborn infants whom crying behaviour was impacted by the age of study product introduction. In the group of infants that received the study product for the first time oats, corn, rice, millet, sage, quinoa, buckwheat are excellent substitutesof wheat proteins and have a very high degree of tolerability. enterocolitis syndrome) for 2 reasons: the onset of symptoms 4 hours after the second introduction of the semolina (clinical symptoms attributable WHEAT AND IMMUNE SYSTEM: IS ALWAYS CELIAC DISEASE? ALWAYS AND IMMUNE SYSTEM: IS WHEAT exact and test), was reported of infants for 1.0% in the breastfed reference group. Daily total crying duration was highly variable with no statistically allergies in humans and possible development of antibiotic-resistant bacterial strains. Antibiotic residues in human milk might have an effect adverse events (AE) (including infantile colic) was reported by study investigators. Crying duration and frequency data were collected daily witha modified Baby Day Diary for the entire intervention period. after one week of age, there was a lower incidence of excessive crying (>3h/d) for infants who received the active IF when compared to the control at 4 weeks of age and soften stools in healthy IF-fed infants. action. The purpose of the treatment should be represented by an adequate growth of the infant affected by allergy to wheat proteins; specifically, Alfonso Rodriguez-Herrera Alfonso A PARTLY FERMENTED INFANT FORMULA COMBINED WITH SCGOS/LCFOS RESULTED IN A LOWER INCIDENCE OF A IN WITH SCGOS/LCFOS RESULTED COMBINED FORMULA FERMENTED INFANT PARTLY A Transfer Protein (Tri a 14). There is an association ProteinTransfer a 14). (Tri between these recombinants and clinical symptoms: specifically, the specific components There is no correlation between these pathologies because IgA of celiac disease and sIgE of wheat allergy share different epitopes. Starting from

Abstracts Table 1: Jorge Cancela Jorge & Medical Writing, Merck KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany; Germany; Darmstadt, Str. 64293 250, Frankfurter KGaA, Merck Writing, & Medical adherence category (Figure 1). The patients with the highest adherence had the highest mean number of data transmissions (10.80 [SD 22.8]) (10.80 [SD 22.8]) transmissions data of number mean highest the had adherence highest the with 1). (Figure patients The category adherence Overall, Results: collected. also were ratio’) (‘non-usage prescribed amount total target the to easypod™) by (as recorded injected actually of r-hGH ratio the and Connect easypod™ to transmissions data of number The [HCPs]). team care the by defined settings easypod™ per as away at the age of 7 month due to uncontrolled bleeding in spite of conservative therapy. conservative of spite in bleeding uncontrolled to due 7month of age away the at ultrasound abdominal acids), (amino screen metabolic her as well as normal was screen virology Her thrive. to failure to due feeding NG and east and Arab region. This Syndrome needs more attention in order to provide suitable management and precisely parental counselling in in counselling parental precisely and management suitable provide to order in attention more needs Syndrome This region. Arab and east eHealth platform easypod™ Connect in 33 countries were analysed. Only data after the 10th injection registered on easypod™ was analysed, analysed, was easypod™ on registered injection 10th the after data Only analysed. were countries 33 in Connect easypod™ platform eHealth compared with the lower adherence groups (intermediate 5.78 [8.35] and low adherence 3.10 [SD 4.30], respectively) and also had the lowest lowest the had also and 3.10 respectively) [SD adherence 4.30], low and 5.78 [8.35] (intermediate groups adherence lower the with compared cause. She was found to have on examination horizontal nystagmus, jaundice and hepatomegaly that was progressive with time. Given the the Given time. with progressive was that hepatomegaly and jaundice nystagmus, horizontal examination on have to found was She cause. 1 Presentation Oral middle the in uncommon but countries few in reported is that acondition mutation gene DGOUK involvement; hepatocerebral with syndrome CAN REAL-WORLDDATA FROMTHEEASYPOD™CONNECTEHEALTH PLATFORM BEUSEDTO PROVIDEINSIGHTS Presentation Oral showed hepatomegaly with normal kidneys. MRI brain was normal, Liver biopsy showed non specific change with evidence of giant cell cell giant of evidence with change specific non showed biopsy Liver normal, was brain MRI kidneys. normal with hepatomegaly showed in challenges and experience our share to is aim Our regions. other from reported cases similar to compared mutation gene DGOUK of result managing this case and to compare the clinical, laboratory and radiographic findings of similar reported cases from other regions. other from cases reported similar of findings radiographic and laboratory clinical, the compare to and case this managing non-usage ratio (0.048 [high adherence] vs. 0.259 [intermediate] and 0.601 [low]). A similar trend was reported at each of the study time points. time study the of each at reported was trend Asimilar [low]). 0.601 and [intermediate] 0.259 vs. adherence] [high (0.048 ratio non-usage with the eHealth platform easypod™ Connect, to allow healthcare professionals to access adherence data. adherence access to professionals healthcare allow to Connect, easypod™ platform eHealth the with Conclusion: We report this 3-month-old female Arab infant who presented to us with jaundice that began in the second day of life, fever and and fever life, of day second the in began that jaundice with us to presented who infant Arab female 3-month-old this We report Report: Case vomiting. She was the second offspring of a first-degree cousin couple who had history of a baby who died at the age of 3 days due to unknown unknown to due days of 3 age the at died who baby of a history had who couple cousin afirst-degree of offspring second the was She vomiting. period. For each individual, patient adherence was calculated as mg of Saizenâ injected vs mg of Saizenâ prescribed, (dosage and frequency frequency and (dosage prescribed, Saizenâ of mg vs injected Saizenâ of mg as calculated was adherence patient individual, each For period. KING ABDULLAZIZ UNIVERSITY HOSPITAL: A CASEREPORT HEPATOCEREBRAL INVOLVEMENT IN AN ARAB INFANT WITHMITOCHONDRIAL DNA DEPLETIONSYNDROMEIN 8813 patients recorded >10 injections: 6410 (72.7%) in the high-adherence category, 1827 (21%) in the intermediate and 576 (6.5%) low- and 1827 the in (21%) category, intermediate the in 6410 >10 high-adherence (72.7%) the in injections: recorded 8813 patients future pregnancies. frequently hereditary, which is uncommon in the Middle East and Arab region. We report an Arab infant with hepatocerebral form of (MDS) as a a (MDS) of as form hepatocerebral with infant Arab an We report region. Arab and East Middle the in uncommon is which hereditary, frequently time and dose injected for patients receiving recombinant human growth hormone (r-hGH; Saizen hormone growth human recombinant receiving patients for injected dose and time to exclude test/training injections. The recorded data period varied, according to the duration of each individual’s treatment within the study study the within treatment individual’s each of duration the to according varied, period data recorded The injections. test/training exclude to 1, over 12 6, 24, 3, easypod™ and via administered therapy, r-hGH to adherence real-world evaluate to was analysis this of aim The Purpose: King AbdullAziz University Hospital, Saudi Arabia; [email protected] Arabia; Saudi Hospital, University AbdullAziz King KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany; [email protected] Germany; Darmstadt, Str. 64293 250, Frankfurter KGaA, Shatha Mohammed Albokhari Mohammed Shatha 36 and 48 months and categorised as high (≥85%), intermediate (>56%–84%) or low adherence (≤56%). adherence low or (>56%–84%) (≥85%), intermediate high as categorised and months 48 and 36 The records of 9022 patients prescribed r-hGH using the easypod™ autoinjector and transmitting their data to the the to data their transmitting and autoinjector easypod™ the using r-hGH prescribed patients 9022 of records The methods: and Materials INTO GROWTH HORMONETREATMENT ADHERENCE? ID: 220 /OP1: 6 220 ID: Introduction: ID: 160 /OP1: 160 5 ID: Introduction: hepatitis. Genetic analysis for DGOUK gene mutation with homozygous variant of uncertain significance c.427T>C (p.Ser143Pro). She passed (p.Ser143Pro).c.427T>Cpassed She significance uncertain of variant homozygous with mutation gene DGOUK for analysis Genetic hepatitis. management conservative of 1) (table spite In time with worse getting was which coagulation, including function liver infant The disturbed markedly had consideration. in was disorders Genetic/Metabolic of possibility the sibling, aprevious of death neonatal and consanguinity of history Medical Devices & Services, Merck KgaA, Route de la Verrerie 6, 1267 Coinsins, Switzerland; Switzerland; 1267 6, Coinsins, Verrerie la de Route KgaA, Merck &Services, Devices Medical Abdominal ultrasonography Alanine aminotransferase Aspartate aminotransferase Alphafetoprotein Gamma-glutamyl transferase Partial thromboplastintime Prothrombin time(PT) Radiographic findings: Direct bilirubin Liver biopsy Lactic acid Laboratory findings: Brain MRI OP1: PRESENTATIONS: ORAL 1 SESSION Patient characteristic baseline 20 9 t h This report describes the clinical, laboratory and radiographic findings of our 3-month-old infant with mitochondrial DNA depletion depletion DNA mitochondrial with infant 3-month-old our of findings radiographic and laboratory clinical, the describes report This

E Mitochondrial DNA depletion Syndrome (MDS) with hepatocerebral involvement is a Autosomal Recessive disorder that is is that disorder Recessive aAutosomal is involvement hepatocerebral (MDS) with Syndrome depletion DNA Mitochondrial The easypod™ electromechanical injection device is unique in electronically transmitting accurate, objective records of the date, date, the of records objective accurate, transmitting electronically in unique is device injection electromechanical easypod™ The D I 1 T 1 , Sandra Guedes , Sandra I O 7 N Topics: Topics: (ALT) (PTT) (AST) (GGT) Endocrinology &Growth Endocrinology Gastroenterology &Metabolism Gastroenterology 2 , Ekaterina Koledova , Ekaterina CONFERENCE PROGRAMME ABSTRACTS 79.5 sec 72 mmol/L Giant cellneonatalhepatitis 228 IU/L 25.7 sec 28319 ng/mL 369 IU/L Normal Bilateral echogenickidneyswithmildfullness 9.8 mmol/L 596 IU/L 3 0.4-2.0 mmol/L Normal level <150 ng/mL 0-5 mmol/L 29- 40sec 11–14 sec 12-78 U/L 15-37 U/L 5- 85U/L

3 Endocrinology Global Medical, Safety & CMO, Merck Merck &CMO, Safety Medical, Global Endocrinology

ORAL PRESENTATIONSORAL ® ) to treat growth disorders. The device works works device The disorders. growth treat ) to 2 R&D Global Biostatistics, Epidemiology Epidemiology Biostatistics, R&D Global 53

Abstracts 54 2 ORAL PRESENTATIONS , Ibrahim Unsal 2 Acıbadem University School of Medicine Department of 2 Department of Emergency Medicine, Cork University Hospital, Cork, 2

, Aysel Ozpinar 2 2 , Mustafa Serteser 2 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE Figure Adherence 1: over 48months Endocrinology & Growth Endocrinology & Growth , Comfort Adedokun 1 , Muhittin Serdar 1 Topics: Topics: N 7 O I 1 T I D Hypercalcemia is anuncommon metabolic disorder in children. Clinical features of hypercalcemia may be nonspecific in Humans obtain >80% of their vitamin D via exposure to the UV-B component of sunlight. Vitamin levels show significant E

Traditionally, treatment of hypercalcaemia involves hyperhydration, loop diuretics, glucocorticoids and low calcium diet. This is thefirst analysis of adherence in a real-world clinical setting using easypod™ Connect.We showed an association h t 9 20 OP1: ORAL PRESENTATIONS: SESSION 1 ORAL PRESENTATIONS: OP1: Department of Paediatrics, Cork University Hospital, Cork, Ireland; Acıbadem University School Of Medicine, Department of Pediatrics, Turkey; between high adherence and high easypod™ data transmission rates. Despite a decreased number of patients in the high-adherence group / OP1: 7 / OP1: ID: 142 higher than the upper limit of normal. Extreme values were excluded by Studentized procedure leaving male test female 47928 and 42118 / OP1: 8 ID: / OP1: 162 hyperparathyroidism underwent parathyroidectomy for solitaryadenoma. All cases were managed on low calcium diet. Bilateral medullary Introduction: hypercalcaemia on routine work up of an unstable neonatein 1 case. They presented with a median corrected serum calcium level of 3.4 (2.96 hypercalcaemia Hypercalciuria (IIH) 4/8 (50%). was evident in 1 case. All cases received intravenous fluids and loop diuretic(furosemide). 4/8 insights into patient behaviours. Introduction: levels were measured by mass spectrometry method and by electrochemiluminescence immunoassay, respectively. As part of routine tests Bisphonates use is gaining more recognition in Paediatrics. It restored normocalcaemia in half of the cases with recalcitrant hypercalcaemia. Medical Biochemistry;Medical [email protected] Materials and Methods: Our study population included 90046 children, male subjects. female 47928 and 42118 Serum 25(OH)D and PTH Kene Ebuka Maduemem Purpose: This study was performed to evaluate the seasonal 25(OH) vitamin D levels and its associations with parathyroid hormone (PTH) of for PTH and vitamin D with correlation analysis. variation in the circulating levels of25-hydroxyvitamin D3 in nonequatorial regions. The normal vitamin D levels are considered to vary for Case Report: describe We the diagnosis, treatment and outcome of8 children males, (2 6 females) with hypercalcaemia seen in a Conclusion: underlying disease. underlying Conclusion: neonates and infants, and is often discovered when a chemistry panel is obtained to evaluate failure-to-thrive. The differential diagnosis is non-usage ratio, quantifying this ratio could help to track drug lost or discarded over time. Further analysis of these data will provide additional Serum 25(OH)D concentrations were measured by Agilent Rapid Res system 1200 LC and Agilent 6460 triple quadruple mass spectrometer nmol/L) L may be insufficient and nmol/L)deficient(4).<20 ng/mL(37.5 Determination of(OH)D 25 levels in children and accurate diagnosis SEASONAL VITAMIN D LEVELS AND PARATHYROID HORMONE VARIATIONS OF 90046 CHILDREN LIVING IN A A LIVING IN OF 90046 CHILDREN HORMONE VARIATIONS AND PARATHYROID D LEVELS VITAMIN SEASONAL CLIMATE SUBTROPICAL nephrocalcinosis was the most common complication Long-term (87%). in 7/8 follow up showed normalised serum calcium with persistent nephrocalcinosis. Ireland; [email protected] Ireland; regional paediatric centre. This cohort has a median years. Presenting age of 0.99 – 14.70) (0.07 features were failure to thrive in 4/8 (50%) Oral Presentation results eligible for vitamin female and D, male 1798 and test 1727 results eligible for PTH data analysis. 3525 pediatric data sets were evaluated Oral Presentation Ozlem Naciye Sahin serum concentrations of predefined tests at Acýbadem LABMED Clinical Laboratories had been (Turkey) performed, between 2005 and 2015. 1 1 different biological needs but >50nmol ) is currently ng.mL L-(>30 -1 considered optimal whilst 25-(OH)D between 20 and 30 ng/mL (37.5-50 complex and varies with age at presentation. includes Treatment hyperhydration, loop diuretic, steroids, bisphosphonates and treatment of cases, incidental renal ultrasound finding post urinary tract infection abdominal in 3/8(37%), symptoms in 1 case and incidental severe over time, after 2 years of follow-up the proportion of high-adherence patients was still high. As high adherence is associated with the lowest of deficiency may involve methodological and clinical challenges due variationsto in season, body mass index(BMI) In and gender(5,6,7,8,9). (Agilent Technologies, Santa Clara, PTH concentrations CA). were determined by an electrochemiluminescence immunoassay with Elecsys (50%) received(50%) oral prednisolone for median a duration days. of 40 Intravenous (7 - 120) pamidronate was used in 4/8. The case of primary analyzer (Roche Diagnostics, Mannheim, Germany). For PTH, values greater than 200 pg/mL were excluded for it corresponds to three-fold addition to these variances different populations may show a different threshold for PTH activation at different vitamin D cut off levels. TREATMENT OF HYPERCALCAEMIA: A CASE SERIES A OF HYPERCALCAEMIA: TREATMENT Turkish children at all pediatric ages and to assess the critical diagnostic threshold level for 25(OH)D deficiency in our pediatric population. - 4.3) mmol/L.- 4.3) The aetiology comprised Williams-Beuren syndrome primary (WBS) 3/8 (37%), hyperparathyroidism idiopathic infantile (12%), 1/8

Abstracts ATOPIC DERMATITIS: CAUSEORCONSEQUENCEOF ALLERGEN SENSITIZATION? AD, sensitization to food and aeroallergens and development of food allergy, asthma and allergic rhinitis were analyzed. were rhinitis allergic and asthma allergy, food of development and aeroallergens and food to AD, sensitization AD, as postulated by the “atopic march” theory. Regarding to respiratory allergy, we consider the follow-up period of our study too short to to short too study our of period follow-up the weconsider allergy, respiratory to Regarding theory. march” “atopic the by postulated AD, as at age18 (15ng/mL, IQR:16).PTH levels were statistically increased, concomitantly with the gradual decrease of 25(OH)D from age one one age from 25(OH)D of decrease gradual the with concomitantly increased, age18at IQR:16).PTH statistically (15ng/mL, were levels and school children, preschool children had significantly higher vitamin D levels than that of school children 25(OH)D (mean 25.31±15.52), 25(OH)D (mean children school of that than levels D vitamin higher significantly had children preschool children, school and and high fidelity simulation. Although the feedback was positive there was a request for smaller groups and more practical experience. Thus, Thus, experience. practical more and groups smaller for request a was there positive was feedback the Although simulation. fidelity high and allergy was made in 12 patients (48%) at a median age of 16 months (range:6-36): egg (10/12), egg (range:6-36): (4/12), 16 of age months (48%) cow´s proteins (3/12), 12 amedian at in milk nuts fruits patients made was fresh allergy (6/25:24%) were diagnosed with respiratory allergy at a median age of 5 years (range:3-6): asthma (5/6) and allergic rhinitis (5/6); all of them (5/6); them of all rhinitis allergic (5/6) and asthma (range:3-6): 5years of age amedian at allergy respiratory with (6/25:24%) diagnosed were patients Six allergies. food multiple (5/12:42%)patients presented (2/12), (2/12) fish (2/12),(1/12). and allergic seafood vegetables these of Five (16/18), (13/18), cow´s proteins milk (4/18), nuts (2/18), fish (1/18), seafood (1/18),fruits fresh (1/18) soya vegetables and (1/18).food of egg Diagnosis (range:3-14), 7months included of age which amedian at sensitization allergen food documented (72%) had (range: 1-7). patients Eighteen caregivers should be set. be should caregivers confidence were collected. A paired T-test was performed to explore statistical significance. statistical to explore performed was paired T-test A collected. were confidence consultation was 8 months (range: 4-12). Median time of follow-up was 4,6 years (range: 2,2-6,4). Twenty patients (80%) had first-degree family family first-degree (80%) had Twenty patients (range: 2,2-6,4). 4,6 years was follow-up (range: of 4-12). time 8months was Median consultation divided into groups of 4 and rotated around 6 workshops, each 30 minutes long. Feedback and pre- and post-course questionnaires exploring exploring questionnaires post-course and pre- and Feedback long. minutes 30 each 6workshops, around rotated 4and of groups into divided 1 Presentation Oral SD, ± ng/L, D (mean vitamin for subjects male to compared when SD, ± 32.7± levels (mean PTH accordingly 16.8) increased significantly sensitized to dust mites. dust to sensitized reliant on first year doctors, known as Foundation Year 1 (Fy1) doctors, to cannulate, perform phlebotomy and assess children with no previous previous no with children assess and phlebotomy perform cannulate, to 1 (Fy1)Year Foundation as doctors, known doctors, year first on reliant Presentation Oral diseases. allergic subsequent march and July, April and July, and July and November revealed an significant difference as their p values were as p<0.023, p<0,032, p<0,032, p<0.023, as were p values their as difference significant an revealed November and July July, and and July, April and march march” theory suggests that early onset and moderate to severe AD may lead to subsequent allergic diseases, probably related to a skin askin to related probably diseases, allergic subsequent to lead may AD severe to moderate and onset early that suggests theory march” GENERAL HOSPITAL INTHEUK Conclusion: between levels PTH of Comparison December. in levels lower to decrease a and August, in peak a June, in increase asignificant with we adapted the course for July 2017 to address these issues for which 24 new doctors attended. After 2 interactive lectures, participants were were participants lectures, 2interactive After attended. doctors 24 new which for issues these 2017 July address for to course the adapted we Cátia Pereira Conclusions: pediatric subjects and highest levels of 25 (OH)D was observed in first year (33 ng/mL, IQR:13.4) and the lowest level was observed observed was level IQR:13.4) lowest the ng/mL, and (33 year first in observed was (OH)D 25 of levels highest and subjects pediatric p<0.033 respectively. Vitamin D levels were significantly lower in female subjects (mean ± SD, 22.3 ng/L, ±14.02) while females had had ±14.02)females ng/L, while SD,22.3 ± (mean subjects female in lower significantly were Dlevels Vitamin respectively. p<0.033 PAEDIATRIC PRACTICAL STUDY DAY FORNEWLY QUALIFIEDDOCTORS, AN EXPERIENCEFROM A DISTRICT PTH activation at different vitamin D cut off levels should be documented and public policies regarding sun exposure rights of children with their their with children of rights exposure sun regarding policies public and documented be should levels off Dcut vitamin different at activation PTH pattern, sinusoidal aseasonal demonstrated levels hormone PTH and 25(OH)D of 31.83±16.06) (mean PTH Analysis (Fig.2). (p<0,0001), Princess Alexandra Hospital NHS Trust, United Kingdom; [email protected] Kingdom; Trust, United NHS Hospital Alexandra Princess Pediatric Allergy Department, between January 2011 and December 2015. Demographic data, risk factors for allergic disease, age of onset of of onset of age disease, allergic for factors risk data, 2015. Demographic 2011 December and January between Department, Allergy Pediatric 25.25±13.4) and PTH levels (mean ± SD, 31.04± 16.3) (p<0.0001). Age dependence of 25(OH)D and PTH levels were examined in 90046 90046 in examined were levels PTH and 25(OH)D of ±SD, (mean 31.04± levels dependence 25.25±13.4) 16.3) Age PTH (p<0.0001). and 85% of cases, before allergic disease develops. Etiology remains unknown and the role of food and aeroallergens is controversial. The “atopic “atopic The controversial. is aeroallergens and food of role the and unknown remains Etiology develops. disease allergic before cases, of 85% through age 18. age through for those starting on paediatrics. Indeed, a number of specialities at Princess Alexandra Hospital, a district general hospital in the UK, are are UK, the in hospital general adistrict Hospital, Alexandra Princess at specialities of anumber Indeed, paediatrics. on starting those for Erin Butterworth Erin Results: The feedback from the course was very positive. very was course the from feedback The Feedback: and Results skills. practical and teaching hands-on on emphasis the with day Fy1 training a Paediatric created we Thus, training. Results: patients. these in allergy respiratory and food of development the assess to and AD severe to moderate with children of acohort To characterize Purpose: Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain; [email protected] Spain; Barcelona, Barcelona, de Universitat Déu, de Joan Sant Hospital take conclusions. More studies are needed to assess the impact of treatment of AD in the prevention of sensitization and development of of development and sensitization of prevention the in AD of treatment of impact the assess to needed are studies More conclusions. take 31.83±16.06) that belong to 3525 of the study population revealed a sinusoidal pattern (Fig.1). Considering vitamin D levels in preschool preschool in Dlevels vitamin (Fig.1). pattern Considering asinusoidal revealed population study the of 3525 to 31.83±16.06) belong that María Teresa Giner Method: Retrospective review of medical records of children admitted for moderate to severe AD from birth to 12 months, in a a in 12 to months, birth from AD severe to moderate for admitted children of records medical of review Retrospective Methods: and Material ID: 232 /OP1: 9 232 ID: Introduction: Becoming a qualified doctor remains a daunting task for the majority of final year medical students (1) particularly students particularly (1) medical year final of majority the for task daunting a remains doctor aqualified Becoming Purpose: and Introduction history of atopy. Median age of onset of AD was 2 months (range:1-5). Fifteen patients (60%) were breastfed until the median age of 5 months 5months of age median the until breastfed (60%) were patients (range:1-5). Fifteen 2months was AD of onset of age atopy. of Median history ID: 176ID: /OP1: 10 barrier dysfunction. Department of Pediatrics, Hospital Santa Maria (CHLN), Lisbon, Portugal; Portugal; (CHLN), Lisbon, Maria Santa Hospital Pediatrics, of Department OP1: PRESENTATIONS: ORAL 1 SESSION We hosted a pilot course in July 2016 and 25 new Fy1s attended. Our initial format involved lectures, large group practical procedures procedures practical group large lectures, involved format initial Our Fy1s new 2016 25 attended. July and in course apilot We hosted Twenty-five patients with diagnosis of moderate to severe AD were included. Fourteen patients were male (56%). Median age at first first at age (56%).Median male were patients Fourteen included. AD were severe to moderate of diagnosis with patients Twenty-five The correlation analysis of 90046 serum 25(OH) D levels (Mean:±SD, 25.31±15.52) and parathyroid hormone levels (Mean:±SD, (Mean:±SD, levels hormone 25.31±15.52) (Mean:±SD, Dlevels 25(OH) parathyroid serum and 90046 of analysis correlation The 20 9 t h Taking into account the global health burden of vitamin D deficiency and its complications, even in sunny countries, threshold for for threshold countries, sunny in even complications, its and Ddeficiency vitamin of burden health global the account Taking into

E Atopic dermatitis (AD) is a chronic inflammatory disease, affecting 10% of children. Onset occurs during the first year of life in life of year first the during occurs Onset children. of 10% affecting disease, inflammatory (AD) achronic is dermatitis Atopic 1 Our results revealed that food allergy, namely egg allergy, is very frequent in patients with early onset and moderate to severe severe to moderate and onset early with patients in frequent very is allergy, egg namely allergy, food that revealed results Our D , Montserrat Álvaro I T 1 I O 7 Andrew Foster, Nickolaos Cholidis Foster, Andrew Solanki, , Pratik N 2 Topics: Topics: , Mònica Piquer , Mònica Allergy, Immunology &Pulmonology Immunology Allergy, General Pediatrics General 2 , Carmen Riggioni CONFERENCE PROGRAMME ABSTRACTS 2 , Ana María Plaza Martín Plaza María , Ana 2 , Yadira Gordon Yadira , 2

2 , Jaime Lozano Jaime , 2 Pediatric Allergy and Clinical Immunology Department, Department, Immunology Clinical and Allergy Pediatric ORAL PRESENTATIONSORAL 2 , Adrianna Machinena 2 , Maria del Mar Folqué Mar del Maria , 55 2 ,

Abstracts 56 P=0.012 P<0.0001 P<0.0001 P<0.0001 P-value ORAL PRESENTATIONS 0.71 (14%) Increase in confidence 1.38 (28%) 1.62 (32%) 1.32 (26%) 51 52 56 taping (cm) Forced ekspiration Forced ®

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 Mode 4 3.61 3.44 3.56 Post-course score 4.00 55 59 54

After Kinesio Deep inspirationDeep 5 5 Mode Mean 4.85 4.85 4.65 4.65 4.9 4.9 4 4.25 4.5 4.65 4.8 4.8 4.75 4.8 4.35 4.5 52 56 49,5 3.29 Pre-course score 2.24 2.24 1.82 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE taping (cm) ® Mean Delivery Delivery Delivery Delivery Delivery Delivery Delivery Delivery Content Content Content Content Content Content Content Content Forced ekspiration Forced 4.7 4.7

General Pediatrics TAPING APPLICATION ON CHEST EXPANSION IN A CHILD WITH JOINT HYPERMOBILITY A IN ON CHEST EXPANSION APPLICATION TAPING ® 52 55 59 Topics: Before Kinesio N 7 O I 1 T Deep inspirationDeep I , Hülya Nilgün Gürses, Kamer Unal Eren, Busra Kepenek Varol D Joint Hypermobility Syndrome refers (JHS) to the increased passive or active movement of a joint beyond its normal range. E

We believe We that such courses are highly valued by newly qualified doctors and will help in their adjustment to working life, However there was no difference between axillary and epigastric regions measurements following the application the of KT, h t 9 20 Chest circumferential measurements Chest OP1: ORAL PRESENTATIONS: SESSION 1 ORAL PRESENTATIONS: OP1: Breaking Bad News workshop Managing unwell children Subcostal Epigastric Sick Child Lecture Safeguarding Lecture Prescribing workshop ENT Examination workshop ENT Safeguarding workshop Sepsis high-fidelity Simulation Practical Skills Prescribing for children Overall Delivery Overall Quality Confidence in…. Axillary Talking to children and their parents to children and their Talking Taking blood from a child Taking Introduction: In regards to the pre- and post-course questionnaires: ID: 286 11 / OP1: increasing balance and functional capacity by supporting joint stability. The aim of this case report is to examine the acute effects of KT on Bezmialem Vakif University, [email protected] Turkey; Scale from 1 (not confident) (veryto 5 confident) Deniz Tuncer Kinesio (KT) Taping is a relatively new therapeutic approach applied for improving muscle function and circulation, decreasing pain, and Feedback scale: 5= Very good; 4= Good;3= Poor 2= Average; Poor; 1=Very Results for individual stations: the acute effect of KT applied to the respiratory muscles of our case with JHS showed an increasing in the rib cage expansion. KT applications Physiotherapy and Rehabilitation was evaluated. A clinical and physical history was obtained, pulmonary function test (PFT) and chest- Rectus Abdominus, M. Obliqus Internus / Externus and M. Transversus Abdominis with muscle facilitation technique. Thoracic expansion was EFFECT OF KINESIO Case Report: A 7-year-old girl with joint hypermobility syndrome with a Beighton score of 8, who was referred to the Department of Pediatric Conclusion: Conclusion: making deep inspirationand forced expiration. The results of the chest circumferential measurements taken from axillary, epigastric, and the SYNDROME measurements from subcostal region increased in deep inspiration and forced expiration. As a result of the findings obtained from the case; subcostal regions,as well as deep inspiration and forced expiration, are shown 1. in Table Oral Presentation stated funding will be made available for future events. circumference measurements were performed. The patient had moderate-severe restrictive type respiratory limitation, which restricts the chest expansion in a child with JHS. expansion of the thorax according to the previous KT were PFT. applied to M. Diaphragmaticus, M. Sternocleidomasteideus, M. Scalenus, M. evaluated form axillar, epigastric and subcostal region with a tape measure before and after taping. The measurements were performed while especially in unfamiliar specialities like paediatrics. This project has been discussed with the East of England Deanery for Paediatrics who Table 1: Table

Abstracts 13 on 15 patients with average 6.9 score (0-10 scale): 10 patients used pharmacological therapy, 4 pharmacological and non-pharmacological non-pharmacological and 4pharmacological therapy, pharmacological (0-10 used 10 scale): score 6.9 patients average with 13 15 on patients 1,00,000 to 1 in 100,000. MAS is caused by a post-zygotic somatic activating mutation of GNAS gene resulting in an increased GSα protein protein GSα increased an in resulting gene GNAS of mutation activating somatic apost-zygotic by caused is MAS 100,000. 1in to 1,00,000 The mean duration of hospitalization was 12.5 days and the mean length of ICU stay was 5.6 days. Infectious/parasitic diseases, congenital congenital diseases, Infectious/parasitic days. 5.6 was stay ICU of length mean the 12.5 and was days hospitalization of duration mean The Yu-Jun Chang Yu-Jun

and immunity disorders were more common in adolescents than school-aged children and young aged children (p < 0.001). Diseases of the the of <0.001). (p Diseases children aged young and children school-aged than adolescents in common more were disorders immunity and < (p adolescents than children young-aged in common more were period perinatal the in originating complications certain and abnormalities, age (<=5 years), school age (>5 years to up to 12 years), and adolescent (>12 18 to 12 to years). years up to adolescent years), years and (>5 age years), school (<=5 age (13/15 patients) are most compromise areas. Quality of life is defined very good from 1, good from 5, acceptable from 7, poor from 2 patients. patients. 2 from from poor 7, acceptable 5, from from good 1, good very defined is life of Quality areas. compromise (13/15 most are patients) (range from 18 to 58). All patients have poliostotic fibrous dysplasia, 10 patients previous peripheral precocious puberty, 3 hyperthyroidism, 1 3 hyperthyroidism, puberty, precocious peripheral previous patients 10 dysplasia, fibrous poliostotic have 18 patients 58). to from All (range emotional and sexual bonds, clinical assistance, social and psychological support. psychological and social assistance, clinical bonds, sexual and emotional etiologies of various age groups. age various of etiologies Presentations conducted in a tertiary medical center during the 5-year study period. All patients transferred to the ICU from the ED were included without without included ED were the from ICU the to transferred patients All period. study 5-year the during center medical atertiary in conducted diseases was respiratory distress syndrome in neonates (13.6%) followed by bacterial pneumonia (9.6%) and status epilepticus (6.9%). There (6.9%). There epilepticus (9.6%) status and pneumonia (13.6%) bacterial by neonates in followed syndrome distress respiratory was diseases decision-making on intensive care unit (ICU) admission. (ICU) unit care intensive on decision-making distinction. Etiologies of the ICU admissions were analyzed by various age groups. Children were divided into 3 groups according to age: young age: to young according 3groups into divided were Children groups. age various by analyzed were admissions ICU the of Etiologies distinction. 1 QUALITY OFLIFE AND HEALTH NEEDS ABOUT TRANSITIONAL CARESFROMPAEDIATRIC TO ADULT AGE IN strengthen management in this age, expanding clinical and patient networks. patient and clinical expanding age, this in management strengthen signaling leading to a scattered hyperfunction of bone cells and endocrine tissues with a wide phenotypic spectrum. phenotypic awide with tissues endocrine and cells bone of hyperfunction ascattered to leading signaling Presentation Oral Presentation Oral GH hypersecretion and 3 patients hypophosphatemic ricket. 13 of 15 patients (86%) continued to receive health cares during adult age: 8 from age: 8from adult during cares health receive to (86%) 13 continued 15 of ricket. patients hypophosphatemic 3 patients and hypersecretion GH Understanding of the epidemiologic data of critically ill children presenting at the ED may help expedite accurate clinical assessments and and assessments clinical accurate expedite ED help may the at presenting children ill critically of data epidemiologic the of Understanding ICU admission. Syndrome) mailing list to MAS patients over 18 years old. We analyze data about clinical manifestations, comorbidities, professional occupation, occupation, professional comorbidities, manifestations, clinical about data We analyze old. 18 over years patients MAS to list mailing Syndrome) musculoskeletal system and connective tissue were more predominant in the school-aged children (p < 0.05). Moreover, the most common of of common most the <0.05). (p Moreover, children school-aged the in predominant more were tissue connective and system musculoskeletal the of diseases and system, respiratory the of diseases system, digestive the of diseases disorders, mental organs, sense and system nervous Conclusion: which display the effects of KT on chest expansion in children with JHS are needed. There is no conflict of interest. of conflict no is There needed. are JHS with children in expansion chest on KT of effects the display which studies, sample larger finding this of light the In flexibility. wall chest of development the for beneficial be may it that suggest physiotherapy with Conclusions: <0.001). (p female than predominant more was Male mortality. with patients ill critically pediatric 289 were urgent clinical condition requiring critical care. The outcome of ICU treatment is also related to the adequacy of the initial ED management. ED management. initial the of adequacy the to related also is treatment ICU of outcome The care. critical requiring condition clinical urgent Changhua Christian Hospital, Taiwan; [email protected] Hospital, Christian Changhua patients have walking impairment, 3 visual defects, 1 hearing deficit, 4 aesthetic problems due to craniofacial fibrous dysplasia. Pain affected affected Pain dysplasia. fibrous craniofacial to due problems aesthetic 4 deficit, 1hearing defects, 3visual impairment, 13 walking have patients endocrinologists. adult from 3case in only neurosurgeons; paediatric 3from orthopaedics, paediatric 2from endocrinologist, paediatric Only 8 (53%) declare to have relevant clinical and psychological support at evaluation-time. at support psychological and clinical relevant have to 8(53%) declare Only PEDIATRIC CRITICAL CASES ADMITTED TO INTENSIVECARE UNITSFROMTHEPEDIATRIC EMERGENCY DEPARTMENT MCCUNE-ALBRIGHT SYNDROME therapies, 1 patient no therapy: average subjective response was 5.0 (0-10 scale). Job activities (9/15 patients) and emotional/sexual bonds bonds emotional/sexual (9/15 and patients) (0-10 5.0 activities was Job scale). response subjective average therapy: no 1patient therapies, Results: The study analyzes quality of life and health needs about transitional care from paediatric to adult age. adult to paediatric from care transitional about needs health and life of quality analyzes study The Purpose: Results: of etiologies the ED and the to presenting patients ill critically pediatric of patterns epidemiologic the investigate to aimed study This Purpose: Daniele Tessaris McCune-Albright Syndrome, Torino, Italy; [email protected] Torino, Italy; Syndrome, McCune-Albright We distribute anonymous semi-structured questionnaires from EAMAS (European Association of McCune-Albright McCune-Albright of Association (European EAMAS from questionnaires semi-structured anonymous We distribute Methods: and Materials This retrospective study of all children aged less than 18 years presenting with critical illnesses to the ED was ED was the to illnesses critical with 18 presenting than years less aged children all of study retrospective This Methods: and Materials Introduction: ID: 133 /OP1: 133 ID: 12 / OP2: 1 /OP2: 166 ID: 0.001). However, injury and poisoning, mental disorders, endocrine, nutritional, diseases of the circulatory system, and metabolic diseases, diseases, metabolic and system, circulatory the of diseases nutritional, endocrine, disorders, mental poisoning, 0.001). and However, injury Introduction: █ Pediatric Endocrinology, Regina Margherita Children Hospital, University of Turin, of Torino, Italy; University Hospital, Children Margherita Regina Endocrinology, Pediatric OP2: PRESENTATIONS: ORAL 2 SESSION █ Time: OP2: PRESENTATIONS: ORAL 2 SESSION We collect data from 15 questionnaires filled out by 2 male patients and 13 female patients, average age at evaluation 31.3 years old old 31.3 years at evaluation age average patients, and female 13 patients male by 2 out filled 15 from questionnaires data We collect Of the 2978 critically ill children transferred to the ICU from the ED, emergency surgeries were performed in 1027 cases (34.5 %). (34.5 1027 in cases performed were surgeries ED, emergency the from ICU the to transferred children ill critically 2978 the Of 20 9 Thursday, 07/Dec/2017:2:00pm-4:00pm•Location:Turin Hall t h Transitional cares from paediatric to adult age represent a difficult moment, especially for rare diseases as MAS: it is desirable to to desirable MAS:is as it diseases rare for especially moment, a difficult represent age adult to paediatric from cares Transitional

E McCune-Albright Syndrome (MAS) is a rare congenital sporadic disorder with an estimated prevalence ranging from 1 in 1in from ranging prevalence estimated an with disorder sporadic congenital arare (MAS) is Syndrome McCune-Albright Admission of pediatric patients from the emergency department (ED) to the intensive care unit (ICU) may indicate an an indicate may (ICU) unit care (ED) intensive the to department emergency the from patients pediatric of Admission Epidemiologic analysis may provide primary clinicians to identify significant differences in admission rates based on different different on based rates admission in differences significant identify to clinicians primary provide may analysis Epidemiologic D I , Wen-Chieh Yang, Chun-Yu Chen, Han-Ping Wu Han-Ping Chun-Yu Yang, Chen, , Wen-Chieh T 1 I O 7 1 N , Patrizia Matarazzo , Patrizia Topics: Topics: Emergency Pediatrics, Epidemiology Pediatrics, Emergency Endocrinology & Growth, Adolescent Health Choices Health Adolescent &Growth, Endocrinology CONFERENCE PROGRAMME ABSTRACTS 1 , Valter Dal Pos Dal , Valter 2 , Luisa de Sanctis de , Luisa

1 ORAL PRESENTATIONSORAL 2 European Association Friends of of Friends Association European 57

Abstracts 58 4 , Maria Céu Machado 1 ORAL PRESENTATIONS FMH, Faculdade de Motricidade Humana (Projecto 2 , IsabelLeal ISAMB, Instituto de Saúde Ambiental, Faculdade de 2,3 3

, Celeste Simões 1,2,3 FM, Faculdade de Medicina/Universidade de Lisboa; Departamento de Pediatria do 4 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE Adolescent Mental Health, Adolescent Wellbeing Adolescent Health Communication Adolescent Health Adolescent Health Choices, Adolescent Wellbeing , Margarida Gaspar Matos 1,2,3 Topics: Topics: Topics: N 7 O I 1 T I D Living with a chronic disease in adolescence can represent a major challenge for adolescents and it may place them at higher Health literacy has (HL) received growing attention in the literature over the years past for 15 its critical role in health education The economic recession that started in 2008-2009, provides an opportunity to study variations in the wellbeing of adolescents E

The heterogeneity and the higher risk of impairment observed reinforce the need to work towardsconsensual procedures, which Parental unemployment may be a driver for further adolescents’ inequalities during economic recessions; thus,further research is h t 9 20 Contradictory results were found in the final included eighteen papers, and most indicated a significantly higher risk of impairment Lower rates of reported wellbeing were found among the adolescents with unemployed parents, and such association increased OP2: ORAL PRESENTATIONS: SESSION 2 ORAL PRESENTATIONS: OP2: William James Center for Research, - Instituto ISPA Universitário, Lisboa, Portugal; ID: 195 / OP2: 3 Introduction: Introduction: ID: 205 / OP2: 4 Introduction: ID: 202 / OP2: 2 it is highly suggested the need to routinely assess HRQoL/psychosocial factors within an individualized framework emphasizing potential improvement of HRQoL and psychosocial care in chronically ill adolescents. living with a CD in adolescence on quality of life health-related (QoL), quality of life (HRQoL) and psychosocial factors. Materials and Methods: The literature review of articles was conducted and identified through PubMed,PsycINFO andPsycARTICLES. Materials and Methods: A repeated cross-sectional study was undertaken. Data from the Portuguese Health Behaviour in School-aged Medicina, Universidade de Lisboa, Portugal; DianaFrasquilho , Margarida Gaspar de Matos Hospital deSanta Maria, CAML,Centro Académico de Medicina de Lisboa, Portugal; [email protected] the relevance of psychosocial factors are still needed. Purpose: Inspired by the vast literature on chronic diseases and also on previous studies that explored and characterized Quality of Life (QoL) Results: Rosemarie Felder-Puig Purpose: were We asked to assess the HL of Austrian adolescents using the HLS-EU concept within the Health Behaviour in School-aged Results: Purpose: This study aims to compare the levels of adolescents’ wellbeing in 2006, according and 2014 2010 to parental employment status, to factors in adolescence is a complex phenomenon, frequently with controversial results. Despite the increasing research inthis area, studies on factors”; “adolescent”. 4) factors), or no significant differences. wasIt also observed heterogeneity in the assessment procedures and substantial difficulties in 2010 and 2014, corresponding and 2014, 2010 to periods prior during, to, and after the economic recession. calculated We the proportion of adolescents HEALTH LITERACY ASSESSMENT IN 13- TO 17-YEAR OLD AUSTRIANS: RESULTS AND MEASUREMENT PROBLEMS AUSTRIANS: RESULTS 17-YEAR OLD ASSESSMENT IN 13- TO LITERACY HEALTH LIFE AND PSYCHOSOCIAL FACTORS AND PSYCHOSOCIAL LIFE Original research papers, published between peer-reviewed; and 2015, 2010 with no restrictions regarding the format/source of interventions protective factors, to considered adolescents as a single/independent group, and, to increase youth’s participation in their own adaptationprocess and, generally, in health promotion. These are possible future directions that could provide multidisciplinary responses towards the Conclusion: Children (HBSC) study, which takes place every four years. with the Boolean “chronic Operator 1) illness” ‘AND’: OR “chronic disease”; “quality 2) of life” OR “health-relatedquality of “psychosocial, life”;3) Conclusion: SYSTEMATIC LITERATURE REVIEW IN ADOLESCENTS WITH CHRONIC DISEASES: (HEALTH-RELATED) QUALITY OF QUALITY CHRONIC DISEASES: (HEALTH-RELATED) ADOLESCENTS WITH IN REVIEW LITERATURE SYSTEMATIC needed and, prevention and interventions are warranted to help protect the well-being of the most vulnerable adolescents. risk for vulnerable health outcomes. Nevertheless, the impact of chronic disease on Health-related Quality of Life (HRQoL) and psychosocial Institute for Health Promotion and Disease Prevention, Austria; [email protected] Oral Presentation survey Health Behaviour in School-aged Children the goal - HBSC of the 2010), present review is to examine recent literature on the impact of Oral Presentation reporting poor wellbeing according to parental employment status andadjusted for sociodemographic factors. Oral Presentation 1 during the period of the economic recession. on QoL/HRQoL and psychosocial factors, whereas others reported a significantly lower risk of impairment(emphasizing possible protective considering adolescence as a single and independent age group. children Survey was used to compare levels of wellbeing among adolescents with employed and non-employed parents, for the years 2006- (HLS-EU) had been presented. From then on, a lot of efforts and ressources were put in HL assessment and improvement. WELLBEING INEQUALITIES IN ADOLESCENTS BEFORE AND AFTER THE RECESSION: PARENTAL UNEMPLOYMENT AFTER THE RECESSION: PARENTAL AND ADOLESCENTS BEFORE WELLBEING INEQUALITIES IN allow for more accurate comparisons between studies. In addition, it is underlined the challenge to find more effective interventions. Moreover, and psychosocial factors in chronically ill Portuguese adolescents at a national-representative level (using the cross-sectional and international and including adolescents years to from old 18 were 13 included. The following sets of keywords were used for reference tracing combined and promotion. In Austria, the concept attracted the attention of political stakeholders after the results of the European Health Literacy Survey and the associations with their day-to-day living conditions. analyze the extent of vulnerability to lower wellbeing that adolescents face during economic recession periods. Aventura Social-Social Adventure Team)/Universidade de Lisboa, Portugal; Aventura Social/HBSC Portugal, Portugal; [email protected] Social/HBSC Portugal; Portugal, Aventura Teresa Cristina Santos AS A SHAPING FACTOR A AS

Abstracts „I don’t know“, but this varied largely across items, ranging from 7% („following the instructions on medication“) to 42% („finding information on on information („finding 42% to medication“) on instructions the („following 7% from ranging items, across largely varied this but know“, don’t „I The parents’ educational level may have a relationship with BMI as well, with the highest level in the normal BMI group (p=0.02). group BMI normal the in level highest the with well, as BMI with arelationship have may level educational parents’ The Tharika NTharika Senevirathne Vitamin D deficiency was taken at serum level of <20ng/ml. of level serum at taken was Ddeficiency Vitamin Although thought to be adequately nourished, micronutrient deficiencies have been identified among the obese and vitamin D deficiency is common. is deficiency D vitamin and obese the among identified been have deficiencies micronutrient nourished, adequately be to thought Although after informed consent, for a period of 3 months. Anthropometric measurements, for BMI calculation, were carried out. Statistical analysis was was analysis Statistical out. carried were calculation, BMI for measurements, Anthropometric 3months. of aperiod for consent, informed after Vithanage Pujitha Wickramasinghe assessment of fasting blood glucose, insulin, lipid profile, ALT, AST, vitamin D, parathyroid hormone and OGTT with 2-hour random blood blood random 2-hour with OGTT and ALT, hormone profile, lipid AST,parathyroid D, insulin, vitamin glucose, blood fasting of assessment an adequate HL. adequate an activity and sedentary behaviours, we found a statistically significant difference in the regular practice of structured exercise (p=0.007), free free (p=0.007), exercise structured of practice regular the in difference significant astatistically found we behaviours, sedentary and activity glucose and insulin. The children in the treatment arm received 50,000 IU of Vitamin D2 weekly for 24 weeks. The supplementation group group supplementation The 24 weeks. for weekly D2 Vitamin of IU 50,000 received arm treatment the in children The insulin. and glucose group. Among eating habits, only the daily consumption of cookies stood out (p=0.008) with prejudice to the overweight/obesity group. Also, Also, group. overweight/obesity the to prejudice with (p=0.008) out stood cookies of consumption daily the only habits, eating Among group. consumption of processed food products, sedentary lifestyles and reduced physical activity are habits that tend to extend into adulthood, adulthood, into extend to tend that habits are activity physical reduced and lifestyles sedentary products, food processed of consumption group, its incorporation into school curricula would be a good and practical approach. practical and agood be would curricula school into incorporation its group, 1 1 OVERWEIGHT AND OBESITY OVERWEIGHT AND We used the 16-item questionnaire which had been developed by HLS-EU researchers from the original 47-item questionnaire, pilot-tested it it pilot-tested 47-item questionnaire, original the from researchers HLS-EU by developed been had which questionnaire 16-item the We used Presentation Oral score, WC, percentage body fat and alkaline phosphatase showed statistically significant decreases across all three groups with marked marked with groups three all across decreases significant statistically showed phosphatase alkaline and fat body WC, percentage score, Trials Registry. Clinical Lanka Sri at registered was study The Lanka. Sri Health, of Ministry Trials the of Clinical and Colombo of University statements about health-relevant tasks, and respondents were asked to judge whether those tasks were „easy“ or „difficult“ for them. We extended We extended them. for „difficult“ or „easy“ were tasks those whether judge to asked were respondents and tasks, health-relevant about statements Improvement in the supplement and placebo group were similar. Improvement in the placebo group could be due to improvement in the feeding feeding the in improvement to due be could group placebo the in Improvement similar. were group placebo and supplement the in Improvement Presentation Oral Surveillance Consultations in a local Family Health Unit and their correlation with overweight and obesity. and overweight with correlation their and Unit Health Family alocal in Consultations Surveillance were given 2500 IU weekly. The participants were followed up monthly at the Clinical Research Laboratory of the Professorial paediatric Unit at at Unit paediatric Professorial the of Laboratory Research Clinical the at monthly up followed were participants The weekly. IU 2500 given were where subjects were randomly allocated to treatment, supplement or control groups. After a 12-hour overnight fast, blood was taken for for taken was blood fast, overnight a12-hour After groups. control or supplement treatment, to allocated randomly were subjects where category response the chose adolescents of fifth one average, the On medication. taking and lifestyles unhealthy to refer handle or understand promotion. health and prevention, disease healthcare, domains three the with information health-related applying and appraising understanding, Conclusion: Conclusion: promoting measures to stimulate regular physical exercise and discourage sedentary behaviours, at home and educational institutions, in order order in institutions, educational and home at behaviours, sedentary discourage and exercise physical regular stimulate to measures promoting performed on Statistical Package for the Social Sciences®, comparing the two groups (normal body mass index (BMI) versus overweight/obesity). versus (BMI) index mass body (normal groups two the comparing Sciences®, Social the for Package Statistical on performed EFFECTS OFVITAMIN DSUPPLEMENTATION ONOBESITY: A RANDOMIZEDCLINICAL TRIAL EATING AND PHYSICAL ACTIVITY HABITSINCHILDREN AND ADOLESCENTS AND THEIRCORRELATION WITH physical activity for at least one hour a day (p=0.003) and screen time for at least two hours a day (p=0.03), all of them favoring the normal BMI BMI normal the favoring them of all (p=0.03), aday hours two least at for time screen and (p=0.003) aday hour one least at for activity physical to reduce the incidence of overweight and obesity, without neglecting the importance of a healthy diet on overall health. overall on diet ahealthy of importance the neglecting without obesity, and overweight of incidence the reduce to This study aims to evaluate the eating and physical activity habits of children and adolescents (3-17 years) observed in Child Health Health Child in (3-17 observed years) adolescents and children of habits activity physical and eating the evaluate to aims study This Purpose: three groups, with marked improvement in treatment group. Vitamin D levels improved in all 3 groups with a significant rise in treatment group. group. treatment in rise asignificant with 3groups all in improved Dlevels Vitamin group. treatment in improvement marked with groups, three Results: To identify the effects of administering vitamin D, in vitamin D deficient obese children. obese Ddeficient D, vitamin in vitamin administering of effects the To identify Purpose: suggested algorithm score global HL the use to right was it whether questionnable was it Therefore, you“). concern that illnessess of treatments to difficult found subjects least the tasks the and problems, health mental to refer handle or understand to difficult found subjects most tasks Results: 2014. of survey HBSC the in collected were Data know“. don’t „I was which category, athird by scale response 2-category this Results: Lady Ridgeway Hospital for Children, Colombo, Sri Lanka. The protocol was approved by the Ethics Review Committee of Faculty of Medicine, Medicine, of Faculty of Committee Review Ethics the by approved was protocol The Lanka. Sri Colombo, Children, for Hospital Ridgeway Lady Sara Rocha Sara Methods: Medicine, Univeristy of Colombo, Sri Lanka; Lanka; Sri Colombo, of Univeristy Medicine, Vitamin D deficient obese children were recruited for a supplementation study. A triple blind RCT was conducted conducted RCT was blind triple study. A supplementation a for recruited were children obese Ddeficient Vitamin Methods: and Material Duarte Ema Maria accessing, of key processes the combining matrix a12-cell as of conceived be can model measurement HLS-EU The Methods: and Materials Introduction: improvement in Vitamin D treatment group. Although statistically not significant, other anthropometric and metabolic parameters improved in all all in improved parameters metabolic and anthropometric other significant, not statistically Although group. Dtreatment Vitamin in improvement in a sample of 72 older children and adolescents and changed some wordings to be easier understood by our target group. The 16 items were were 16 The items group. target our by understood easier be to wordings some changed and adolescents and children older 72 of asample in / OP2: 6 /OP2: 223 ID: highlighting the importance of raising awareness and adopting preventive measures. preventive adopting and awareness raising of importance the highlighting Introduction: hours of sleep seem to be related with BMI, with the normal BMI group sleeping 35 more minutes than the overweight/obesity group (p=0.01). (p=0.01). group overweight/obesity the than minutes more 35 sleeping group BMI normal the with BMI, with related be to seem sleep of hours / OP2: 5 /OP2: 277 ID: by HLS-EU researchers, and to equate the „I don’t know“ with the „difficult“ responses. Doing so, only 37% of Austrian adolescents would have have would adolescents Austrian of 37% only so, Doing responses. „difficult“ the with know“ don’t „I the equate to and researchers, HLS-EU by Department of Paediatrics, Univeristy of Colombo, Sri Lanka; Lanka; Sri Colombo, of Univeristy Paediatrics, of Department Hospital de Santarém, Portugal; Portugal; Santarém, de Hospital OP2: PRESENTATIONS: ORAL 2 SESSION 95 children were recruited and randomized to the three arms of the study, supplement (33), treatment (31) and placebo (31). (31) (33), placebo treatment BMI-Z and supplement study, the of arms three the to randomized and recruited were children 95 We obtained data from 3,950 adolescents aged 13, 15 and 17 years and attending different types of school all over the country. The The country. the over all school of types different 13, 15 attending aged 17 and and years adolescents 3,950 from data We obtained We had a sample of 117 individuals, 55.6% females, with a mean age of 9 (±4.4) years, 69.2% with a normal BMI. Regarding physical physical Regarding BMI. anormal with 69.2% 9(±4.4) of years, age amean with females, 55.6% 117 of asample We had individuals, Questionnaire about eating habits, physical activity and socio-economic status completed by parents or self if older than 14 years, 14 than years, older if self or parents by completed status socio-economic and activity physical habits, eating about Questionnaire 20 9 t h Physical activity seems to have a greater impact on BMI than eating habits, emphasizing the importance of developing and and developing of importance the emphasizing habits, eating than BMI on impact agreater have to seems activity Physical Further work should be invested in validating HL instruments for use in children and adolescents. To promote HL in this target target this in To HL promote adolescents. and children in use for instruments HL validating in invested be should work Further

Vitamin D, apart from being crucial in bone metabolism, plays an important role in insulin secretion and maintaining glucose homeostasis. homeostasis. glucose maintaining and secretion insulin in role important an plays metabolism, bone in crucial being from D, apart Vitamin 1 E , João Soares Ferreira Soares João , Alongside the increasing incidence of childhood obesity, are changes in eating habits and physical exercise. Greater Greater exercise. physical and habits eating in changes are obesity, childhood of incidence increasing the Alongside D I T 1 I O 7 N 2 , Liza Aguiar , Liza Topics: Topics: 1 , Amali NHerath , Amali Obesity & Physical Activity &Physical Obesity Obesity & Physical Activity &Physical Obesity 2 1 Unidade de Saúde Familiar São Domingos, Santarém, Portugal; [email protected] Portugal; Santarém, Domingos, São Familiar Saúde de Unidade CONFERENCE PROGRAMME ABSTRACTS 1 , Shamini GS Adikaram GS Shamini , 2 , Pedro Mantas Pedro , 1 , Hasika Dilhani Jayasekera Dilhani , Hasika 4 Lady Ridgeway Hospital, Colombo, Sri Lanka; [email protected] Lanka; Sri Colombo, Hospital, Ridgeway Lady 1 , Ana Luísa Martins Luísa Ana , 2 , Dulani BDL Samaranayake 2 Colombo South Teaching Hospital, Sri Lanka; Lanka; Sri Hospital, Teaching South Colombo

1 2 , Nuno Magalhães Nuno, ORAL PRESENTATIONSORAL 3 , Navoda , Atapattu Navoda 2 , ClarisseAguiar, 3 4 Department of Community Community of Department , Lakshika Kendaragama 2 , Rafaela Coelho Rafaela , 59 2 4 , ,

Abstracts 60 1 1,2,3 , Nada Malik 3 , Hatim mohamed Abdulrahman 1 ORAL PRESENTATIONS , Manal Mohamed Khalid Elhussien 2 Mogtrbeen University; [email protected] University; Mogtrbeen 3 Clinical Hospital Bitola, Macedonia, Former Yugoslav Republic of; 2 Sidra Medical and Research Centre-Qatar; [email protected]

3 , Mohamed sobhy Khalifa 1,3 2 Ministry of Health Khartoum State; 2 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE Weill Cornell Medicine - Qatar; , Fatma Sharhabeel Margani Mohammed 2 1 , Manasik kamil Hassan 1,2,3 Nutrition & Diets, Adolescent Wellbeing General Pediatrics, Nutrition & Diets Neurology , Teuta Useini Avdi 1 Topics: Topics: Topics: N 7 O I 1 T I D The wide range of symptoms and signs of temporal lobe epilepsy consists of motor manifestations, abdominal pain and oral, Adolescents are at a great risk of nutritional problems, because of the hormonal and physiological changes that affect their life E

Our study showed that parents are more likely to identify their children as being picky eaters than physicians, in addition, there A strict dietary and physical activity regimen could improve vitamin D status in obese children and some of the anthropometric Sudanese adolescent children consume a balanced diet except for less preference of fruits. h t 9 20 A total of (136) questionnaire A total of (136) analyzed; among the children a mean age of 5 years old. of mothers 75% were responsible for feeding Age of the studied population range Female between years, children %). – 15 the majority 10 comprised (47.2 were between 12-13 OP2: ORAL PRESENTATIONS: SESSION 2 ORAL PRESENTATIONS: OP2: General Hospital Prilep, Macedonia, Former Yugoslav Republic of; The National Ribat University, Sudan; Hamad Medical Corporation, Qatar; behavior. Better understanding family dynamics and mealtime interactions will help in improving parenting feeding styles and decrease ID: 263 / OP2: 8 ID: 297 / OP2: 7 habits with the dietary advice that was provided and reduction in the fat mass. 33% of the treatment group sufficient levels of vitamin D while in hand or verbal automatisms. They originate from medial or neocortical region of temporal lobe. Electroclincal features depend on the age of the Introduction: Introduction & purpose: Eating behavior in children is considered part of their growth and development; one those behaviors is picky Introduction: ID: 235 / OP2: 9 Materials and Methods: retrospective observational study conducted in two medical centers. Data were collected from medical histories Materials & Methods: A learning facility based cross section study, conducted in basic schools in Khartoum, Sudan. Carried out in 25 primary Materials and Methods: A cross sectional single institution retrospective study was done at Hamad Medical Corporation in general pediatrics Results: the other two groups the it was about 10%. Purpose: to present our experience in diagnosis, treatment and follow-up of children with temporal lobe epilepsy. teachers and they were informed that their participation is totally voluntary. Results: Purpose: The aim of this study was to determine the food pattern of Sudanese adolescent school children. Elmuntasir Mohamed Taha Salah food of parents (62%) physicians,refusal vs (53%) of to physician’s eat avoiding at of meal parents time p value new and (44%) (0.001), (21%) food and prefer liquid over solid respectively. and (50%) (44%) NUTRITIONAL HABITS PROFILE AMONG SUDANESE ADOLESCENTS SUDANESE AMONG HABITS PROFILE NUTRITIONAL PHYSICIANS IN PEDIATRIC AMBULATORY SETTING - QATAR SETTING AMBULATORY PHYSICIANS IN PEDIATRIC perception of child picky eater and to identify factors that might lead to modifying such behavior and feeding practice. Gabriela Tavchioska was a good correlation between parent’s perception and their child’s actual BMI. Both groups shared same concerns regarding picky eater Conclusion: Conclusion: while only a very small percentage prefer to eat fruits. Soft drink of students was consumed by 37.4% Conclusion: negative parent–child negative interactions matching low body mass index for their kids where physician’s the p value BMI (72%) point was (0.016) <15 of view was less compering to BMI Oral Presentation Oral Presentation CHILDREN’S EATING BEHAVIOR; A COMPARISON OF THE ATTITUDE AND PERCEPTION OF FAMILIES AND OF FAMILIES AND PERCEPTION ATTITUDE OF THE COMPARISON A BEHAVIOR; CHILDREN’S EATING school children for boys and girls distributed boys schools as 12 girls and 13 schools. Schools chosen for this study comprised all groups of society namely medium low, and high-income group. The sample size was 380. Informed consent was obtained from the participants and their Oral Presentation style and food habits and affect nutrient intake. 1 1 1 of the children (50%) p value (0.17) . Theof the most children common p value (50%) (0.17) behaviors of a picky eater among the group responding included; taking less variety of outcomes of childhood obesity. Further large scale studies are needed. child. Neurodevelopmental impact such as cognitive decline mostly depends on duration of epilepsy. of children from 6 moths years with to 14 temporal lobe epilepsy. Results: Out children of 32 children, younger 4 (12,5%) than one year have clinics. The survey includes details of demographic, several questions to explore the perception of picky eater among parents and physicians,compare the relation between truly parents concern and the physicians evaluation for the kids regarding feeding habits and how it is affectingchildren the growth. only 3% prefer fast foods. 55.2% of students drink milk daily. 70% of students eat green salad daily and 42% of students prefer to eat meat growth, poor appetite and not getting optimal vitamins from meals compere to physician’s concern p value (0.005). Family (43%) concern was [email protected] eater. Thereeater. is no single widely accepted definition of picky eating. Our aim from this study is exploreto and compare parents and physicians and scheduling meals. Almost 58% of parents stated that they are considering their children as picky eater and have concerns about their and metabolic profiles, but high dose vitaminD, enhances those improvements. Therefore high dose vitamin D would potentiate management Ahmed hassan Alhammadi hassan Ahmed 47.0 % and male children47.0 were 53%. Fifty five percent of the students took 3 meals 69%per of day. prefer to eat beans in breakfast meal while TEMPORAL LOBE EPILEPSY: ELECTROCLINICAL FEATURES, MANAGEMENT AND NEURODEVELOPMENTAL IMPACT AND NEURODEVELOPMENTAL MANAGEMENT FEATURES, ELECTROCLINICAL LOBE EPILEPSY: TEMPORAL

Abstracts Tiago Augusto Paiva de Magalhaes de Paiva Augusto Tiago and regular follow-up and close collaboration between health institutions with different level of health care. health of level different with institutions health between collaboration close and follow-up regular and a cardiopulmonary exercise-training test (CPET) and were then randomized into a training group or a control group. The training group received received group training The group. acontrol or group atraining into randomized then were and (CPET) test exercise-training a cardiopulmonary antiepileptic drug, 7 (21,8%) are on double antiepileptic therapy and 1 (3%) child is receiving three antiepileptic drugs. Neurodevelopmental Neurodevelopmental drugs. antiepileptic three receiving is 1(3%) and child therapy antiepileptic 7(21,8%) drug, double on are antiepileptic associated with urticaria that quickly evolved into bullous lesions and systemic hypotension that needed adrenergic support. Following these these Following support. adrenergic needed that hypotension systemic and lesions bullous into evolved quickly that urticaria with associated electroencephalography. Magnet resonance changes were found in 7 (21,8%) children. Currently 24 (75%) children are treating with one one with treating are 24 (75%) children Currently 7(21,8%) in found were children. changes resonance Magnet electroencephalography. episodes, corticosteroids and ketotifen were added to her treatment, so far with good response. good with far so treatment, her to added were ketotifen and corticosteroids episodes, of acute worsening of the skin lesions along with vomiting and diarrhea. Due to the suspected diagnosis of mastocytosis, a skin biopsy was was biopsy askin mastocytosis, of diagnosis suspected the to Due diarrhea. and vomiting with along lesions skin the of worsening acute of tissues. in infiltration cell mast increased and release cell-mediator mast from results presentation clinical of electroclinical features showed that 24 children experienced partial seizures, 4 children had verbal attacks, 3 children had general general had 3children attacks, verbal had 4children seizures, partial experienced 24 children that showed features electroclinical of of surgical procedures, long-term outcomes are expected to be promising. However, patients face a high mortality and morbidity risk and and risk morbidity and mortality ahigh face However, patients promising. be to expected are outcomes long-term procedures, surgical of improvements to Due ventricle. right by a pumped being without lungs, the through passively flows blood venous systemic the operation, operation. Inspiratory muscle training increases exercise capacity in terms of work rate and improves oxygenation at rest and during exercise. during and rest at oxygenation improves and rate work of terms in capacity exercise increases training muscle Inspiratory operation. clinical manifestations can either be limited to the skin but also have systemic involvement or be potentially fatal. potentially be or involvement systemic have also but skin the to limited be either can manifestations clinical flushing of episodes severe for department emergency the to 3visits had patient the report, case this to previous 2months the In cromoglycate. delay due to uncontrolled seizures or brain structural changes was estimated in 9(28,1%) in estimated was children. changes structural brain or seizures uncontrolled to due delay 1 Presentation Oral CUTANEOUS MASTOCYTOSIS: BULLOUSFORM– A CASEREPORT Presentation Oral study was to evaluate the effects of inspiratory muscle training on exercise capacity and hemodynamic values in Fontan patients. Fontan in values hemodynamic and capacity exercise on training muscle inspiratory of effects the evaluate to was study months, skin thickening with rough-textured and yellowish maculae started to appear mainly on the scalp and trunk with sporadic episodes episodes sporadic with trunk and scalp the on mainly appear to started maculae yellowish and rough-textured with thickening skin months, may suffer of residua or sequela such as arrhythmias, heart failure, thromboembolic events, liver dysfunction or protein-losing enteropathy. enteropathy. protein-losing or dysfunction liver events, thromboembolic failure, heart arrhythmias, as such sequela or residua of suffer may Conclusion: Conclusion: We describe a 21 months old female infant with familial history of anetoderma (mother). The patient had no medical history until until history medical no had patient The (mother). anetoderma of history familial with infant female old a21 months We describe report: Case Conclusion: performed which showed severe mast cells infiltration on the dermis. Laboratory tests revealed increased serum tryptase levels (49,8 mcg/L). mcg/L). levels (49,8 tryptase serum increased revealed tests Laboratory dermis. the on infiltration cells mast severe showed which performed Patients were asked to train daily for 10-15 minutes. The control group did not receive any intervention. After 6 months all patients were restudied again. restudied were patients all 6months After intervention. any receive not did group control 10-15 for The daily minutes. train to asked were Patients Paediatrics, Technische Universität München, Munich, Germany; Germany; Munich, München, Universität Technische Paediatrics, Patients’ needs concerning activities in daily life and the desire to perform sports should be regarded and considered individually. To enhance To enhance individually. considered and regarded be should sports perform to desire the and life daily in activities concerning needs Patients’ Parents were instructed in order to avoid possible mast cells degranulation precipitating factors and started treatment with antihistamine and and antihistamine with treatment started and factors precipitating degranulation cells mast possible avoid to order in instructed were Parents female) were recruited. Instable patients or those undergone recent interventions, or changes in medication were excluded. All patients performed performed patients All excluded. were medication in changes or interventions, recent undergone those or patients Instable recruited. were female) Department of Pediatrics, Integrated Pediatric Hospital, Centro Hospitalar S.João, Porto - Portugal; [email protected] -Portugal; Porto S.João, Hospitalar Centro Hospital, Pediatric Integrated Pediatrics, of Department training compared to the control group (p <.014). None of the patients in the training group became cyanotic (<90%) during exercise anymore. exercise during (<90%) cyanotic became group training the in <.014). (p patients the group of None control the to compared training Results: the age of 6 months when her parents noticed bullous lesions located on the scalp and seating position pressure points. From the age of 12 of age the From points. pressure position seating and scalp the on located lesions bullous noticed parents her when 6months of age the tonic-clonic seizures and one child had severe abdominal pain. Spike-slow wave complexes in temporal leads were found in interictal interictal in found were leads temporal in wave complexes Spike-slow pain. abdominal severe had child one and seizures tonic-clonic 17 and (53,1%) 14 5years Analysis 6to 1to from from years. group group age age the the in 11 in epilepsy, (34,3%) lobe children temporal Rhoia Clara Neidenbach In Fontan patients, the ventilatory pump may augment the blood fl blood the augment may pump ventilatory the patients, Fontan In Purpose: Forty consecutive, clinically stable children after Fontan operation (mean age 12.3 ± 2.2 years, range 8 to 17 years, 25% 17 8to 25% years, range years, 12.3 ±2.2 age (mean operation Fontan after children stable clinically consecutive, Forty Methods: and Materials Nowadays surviving into adulthood, Patients experience higher individual demands on exercise performance and health development. health and performance exercise on demands individual higher experience Patients adulthood, into surviving Nowadays Bolzano, Südtirol; [email protected] Both bone biopsy and myelogram showed no sign of medullary infiltration by mast cells. Abdominal ultrasound also did not show any alteration. alteration. any show not did also ultrasound Abdominal cells. mast by infiltration medullary of sign no showed myelogram and biopsy bone Both INSPIRATORY MUSCLETRAININGINCHILDREN AFTER FONTAN OPERATION INCREASESOXYGENSATURATION instructions to an inspiratory ventilatory muscle training with a POWERbreathe® device, which was weekly adapted to the patients’ individual level. level. individual patients’ the to adapted weekly was which device, aPOWERbreathe® with training muscle ventilatory inspiratory an to instructions in the forced vital capacity (FVC) in both groups, and an increase of VO2peak by 3.0%. Oxygen saturation at rest was significantly higher after the the after higher significantly was rest at saturation Oxygen 3.0%. by VO2peak of increase an and groups, (FVC) both in capacity vital forced the in / OP2: 10 187 /OP2: ID: Introduction: Introduction: / OP2: 11 /OP2: 256 ID: Fontan after adults and children of program rehabilitative the in included be should training muscle inspiratory preventive development, health Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum München; München; Herzzentrum Deutsches Disease, Heart Congenital and Cardiology Pediatric of Department OP2: PRESENTATIONS: ORAL 2 SESSION In the training group, work rate increased on average by 14% compared to 6.5% in the control group (p=0.425). There was a 10% increase a10% was increase There (p=0.425). group control the in 6.5% to 14% by average on compared increased rate work group, training the In 20 9 t h Management of temporal lobe epilepsy is complex with need of comprehensive diagnostic tools, access to modern therapies, therapies, modern to access tools, diagnostic comprehensive of need with complex is epilepsy lobe temporal of Management After a Fontan palliation, a lifelong follow-up by an experienced specialist in complex congenital heart disease (CHD) is essential. (CHD) essential. is disease heart congenital complex in specialist experienced an by follow-up alifelong palliation, aFontan After We describe a case of cutaneous mastocytosis in its bullous form illustrating the complexity of this disorder; particularly how how particularly disorder; this of complexity the illustrating form bullous its in mastocytosis cutaneous of acase We describe

E Mastocytosis is a disorder characterized by an abnormal proliferation and accumulation of mast cells within tissues or organs. Its Its organs. or tissues within cells mast of accumulation and proliferation abnormal an by characterized adisorder is Mastocytosis The Fontan procedure is a palliative surgical procedure in patients with a functional or anatomic single ventricle. After a Fontan aFontan After ventricle. single anatomic or afunctional with patients in procedure surgical apalliative is procedure Fontan The D I T 1 I O 7 N Topics: Topics: 1 , Renate Oberhoffer Renate , Rare Diseases, Child Mental Health Mental Child Diseases, Rare General Pediatrics General CONFERENCE PROGRAMME ABSTRACTS , Sara Fonseca, Ana Maia, Ana Paula Fernandes Paula Ana Maia, Ana Fonseca, , Sara 1,2 , Nicole Nagdyman 3 Verein Kinderherz - Associazione per i bambini con malattie cardiache, cardiache, malattie con ibambini per -Associazione Kinderherz Verein

1 , Ulrich Seitz Ulrich , ow by increasing venous return within inspiration. The aim of this this of aim The inspiration. within return venous increasing by ow 3 , Peter Ewert , Peter ORAL PRESENTATIONSORAL 1 , Harald Kaemmerer Harald , 2 Department of Preventive Preventive of Department 1 , Alfred Hager Alfred , 61 1

Abstracts 62 2 Apollonion Hospital,Cyprus; angerigas@ ApollonionHospital,Cyprus; 3 ORAL PRESENTATIONS , Mamas Theodorou 1 Open University of Cyprus; 2

, Thalia Papadouri 3 , Angelos Rigas 2 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE Preterm Infant, NICU General Pediatrics , Petros Galanis 1 Topics: Topics: , Abu Syed Golam Faruque N 7 O I 1 T I D Several maternal factors such as the Body Mass Index (BMI) prior to pregnancy and weight gain during the pregnancy affect Fever is common and mostly caused by benign self-limiting infections and which is an easily recognizable primary sign, for many E

Women with low Body Mass Index before pregnancy or low weight gain during pregnancy, are at increased risk for premature Diarrhea with fever were more likely to be associated with older age stratum, seasonality, non sanitary toilet, stool frequency, h t 9 20 Our results indicate a statistically significant increased incidence of preterm delivery (p<0.001), statistically significant lower Diarrhea with febrile children were more likely to be wasted (<–2 weight-for-height and p<0.001)] underweight z-score) vs. 14%; [(20% OP2: ORAL PRESENTATIONS: SESSION 2 ORAL PRESENTATIONS: OP2: Neonatal Intensive Care Unit, “Archibishop Makarios III Hospital”; birth and babies with low birth weight, when compared to women with normal BMI and normal weight gain during pregnancy. The [2.17 (1.67-2.82)] after controlling (1.67-2.82)] for other covariates.[2.17 ID: 188 / OP2: 13 implementation of preventive measures within the context of health policy, aimed at maintaining normal BMI for women and correct nutrition Introduction: ID: 190 / OP2: 12 Introduction: icddr,b, Bangladesh, People’s Republic [email protected] of; BMI. Following the calculation of the BMI, women were categorised into 5 groups. also We recorded the gestational age and birth weight of Mass Index (BMI<19.9 The kg/m2). reduced number of kilos gained during pregnancy indicates a statistically significant increased frequency of Material and Method: This is a prospective research carried out in Cyprus from March to April The 2015 participants 2016. were women with Materials and Methods: From January to December 2010 a total 2012, of 3,570 children of under-5 years with diarrhea were visited to a Shahnawaz Ahmed LBWN (p<0.001) and a lower gestational age of the newborn (p<0.001). Results: Purpose: investigate To the effect of the pre-pregnancy Body Mass Index (BMI) of the expectant mother and the weight gained during the Paraskevi Stylianou-Riga Purpose: Due to the scarcity of information regarding the febrile diarrhea, we anticipated to explore socio-demographic, clinical, and host tertiary level hospital in rural Bangladesh. A total of 2979 of these(83%) children were reported diarrhea without were fever and (16%) 591 Results: FEBRILE DIARRHEA AMONG UNDER-5 CHILDREN: A FACILITY BASED OBSERVATION IN RURAL BANGLADESH IN RURAL BASED OBSERVATION FACILITY A CHILDREN: AMONG UNDER-5 FEBRILE DIARRHEA pregnancy (numberof additional kilos) on the newborn’s birth weight, the incidence of preterm birth and the degree of prematurity observed. vomiting, convulsion, dehydration (moderate- and severe) Shigella with diarrhea without Further fever. extensive study will be needed to better weeks) (cohort group) and 349 women who carried their pregnancy to term (>37 weeks) (control The group). aim was to collect data relating the women’s weight gain in kilos during (kg) pregnancy, their height in centimeters and their weight just prior to pregnancy, in order to calculate their Conclusion: Conclusion: understanding about the disease to develop the treatment strategy to reduce disease burden. yahoo.gr newborns. The statistical analysis was performed using the statistical IBM SPSS 21.0 package. markers of pregnancy outcome, such as the gestational age and the newborn’s birth weight. single pregnancy, giving birth in a private or state hospital. Questionnaires were administered to 348 women who gave birth prematurely (<37 Oral Presentation Oral Presentation significant associations number diarrhea with fever were observed seasonality(1.12-1.68)], with[1.37 age1.65(95% CI-1.29-2.12)], stratum [OR: serious childhood infections. But when fever accompanies with infectious disease such as diarrhea become worried some and made parents OUTCOME. A STUDY ON CYPRIOT POPULATION. STUDY A OUTCOME. 1 during pregnancy is necessary, since they have a significant impact on the pregnancy outcome. gestationalage (p<0.001), and an increased frequency of low birth weight newborns (LBWN) (<2,500 grams) (p=0.001) in women with low Body of stool [1.30 (1.07-1.59)], vomiting [1.57 (1.27-1.94)], dehydration (moderate- severe) [1.73 (1.73-1.28)], convulsion [6.90 (3.75-12.71)], Shigella convulsion [6.90 dehydration (3.75-12.71)], (1.73-1.28)], (moderate- [1.73 severe) vomiting (1.27-1.94)], [1.57 of stool (1.07-1.59)], [1.30 characteristics of diarrhea with fever among under-children 5 who presented in rural Mirzapur, Bangladesh. cases and the remaining children (n=2,979, were 83%) not reported with fever and formed the comparison group. enrolled as diarrhea Sixteen with fever. percent of the enrolled 16%) (n=591, children were suffering from diarrhea considered with fever, to be (<–2 weight-for-age p<0.007)] z-score) vs. compared 21%; [(26% to diarrhea without Older fever. age group (24-59 months) vs.16%; [(32% anxious and drove care seeking. June but vs. October [(50% 39%; <0.001)], to February were the peck of diarrhea without In multivariate vs. fever 46%; [(32% <0.001)]. analysis, THE EFFECT OF PRE-PREGNANCY BODY MASS INDEX AND WEIGHT GAINED DURING PREGNANCY ON PREGNANCY ON GAINED DURING PREGNANCY AND WEIGHT MASS INDEX BODY THE EFFECT OF PRE-PREGNANCY <0.001)] children<0.001)] were more complaints of diarrhea. Seasonal peaks of diarrhea with fever were observed in during the months of March, and

Abstracts

algorithm and its further evaluation. further its and algorithm affected. Leukocytosis was present in 32.9% and C-reactive protein was positive in 89.2%. Evaluation by Stomatology/Dentist was requested requested was Stomatology/Dentist by Evaluation 89.2%. in positive was protein C-reactive and 32.9% in present was Leukocytosis affected. association ad-initium. Amoxicillin+clavulanic acid was used in 81.9%, clindamycin in 25.6% and cephalosporin in 12.8%. The evolution was was evolution The 12.8%. in cephalosporin and 25.6% in 81.9%, in clindamycin used was acid Amoxicillin+clavulanic ad-initium. association although sometimes neglected by Paediatricians. by neglected sometimes although (0.26; 0.07-0.92; p=0.037) and absence of purulent material on ultrasound (0.07; 0.02-0.29; p<0.001). Size of lymph node (0.98; 0.96-1.00; (0.98; 0.96-1.00; node lymph of p<0.001). Size (0.07; 0.02-0.29; ultrasound on material purulent of absence and 0.07-0.92;(0.26; p=0.037) consultation to prior use (0.91;(OR; 95%CI):(1.17; antibiotic count age no p=0.001), 0.87-0.96; cell blood white absolute 1.06-1.29; p=0.002), (yes/no). ultrasonography at material purulent (x10^9/L), and (p=0.015). The presence of trismus on admission was associated with longer hospitalization time (p=0.003). An association was found between between found was association An (p=0.003). time hospitalization longer with associated was admission on trismus of presence The (p=0.015). conservative management should include those predictive factors. predictive those include should management conservative decade. last the over published been have guidelines Presentations others, age (years), size of lymph node (mm), fever (38,5°C) and antibiotic use prior to consultation, fluctuation, absolute white blood cell count count cell blood white absolute fluctuation, consultation, to prior use (mm), antibiotic node and (38,5°C) fever lymph of (years), size age others, among including, covariates, independent potential several with models regression logistic univariate performed we outcome, afavorable of disease, Cat-scratch disease, Kawasaki adenitis, were: mycobacterial criteria Exclusion LBACL. was diagnosis final the which of mass cervical of them had records of oral health in the follow up. Prior antibiotic therapy was associated with initiation of more than one drug on admission admission on drug one than more of initiation with associated was therapy antibiotic Prior up. follow the in health oral of records had them of sought percent (75.0%). Fifty-eight frequent most the being 94.1%, cavity in dental with admission to previously existed 11.8%.of disease Oral of periapical abscess, during a 10-year period (2007-2016). period a10-year during abscess, periapical of defined as outpatient treatment or hospital stay of 48 hours or less without surgical drainage. To identify factors at initial consultation predictive predictive consultation initial at factors identify drainage. To surgical without less or hours 48 of stay hospital or treatment outpatient as defined dental cavities (55.4%), dental abscess (54.4%) and trismus (18.1%) were the most common findings. In 75,7% of cases permanent dentition was was dentition permanent cases In 75,7% of (18.1%) (54.4%) findings. trismus and (55.4%), abscess common most cavities dental the were dental days). In the last six years, the number value of admissions to Paediatric Emergency Department doubled, with an average hospitalization rate rate hospitalization average an with doubled, Department Emergency Paediatric to admissions of value number the years, six last days). the In 1 OUTCOME Presentation Oral for eligible patients identify to algorithm Adecision lymphadenitis. cervical acute bacterial likely with children other than evolve better to seem Presentation Oral Université Laval; Laval; Université medical care before the admission, 46.8% had initiated antibiotic therapy and 2.1% underwent exodontia. The most common reported symptoms symptoms reported common most The 2.1% exodontia. and therapy underwent antibiotic initiated had 46.8% admission, the before care medical years old that have consulted for LBACL between July 1st 2010 and July 31st 2015 at a tertiary care pediatric center. LBACL were identified identified were LBACL center. pediatric care 31st 1st 2010 July July 2015 and atertiary at between LBACL for consulted have that old years Conclusion: using 2 electronic record databases (hospitalization, emergency). Patients were included if they had acute (≤10 days) episode of unilateral unilateral of (≤10 acute days) had episode they if included were Patients emergency). (hospitalization, databases record 2electronic using were odontalgia (77.7%) and cellulitis (64.9%). The mean time to presentation was five days. On physical examination, facial cellulitis (93.3%), cellulitis facial examination, physical On days. five was presentation to time mean (64.9%). (77.7%) The cellulitis and odontalgia were unfavorable in 12.8%. The mean duration of treatment was 11.9 days. Eighty-nine percent were directed to hospital consultation but only 2.4% 2.4% only but consultation hospital to directed were percent 11.9 was treatment of Eighty-nine days. duration mean The 12.8%. in unfavorable Cátia Leitão Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal; [email protected] Portugal; Gaia/Espinho, de Nova Vila Hospitalar Centro p=0,057) or fluctuation (0.71; 0.21-2.39; p=0.57) did not achieved statistical significance. statistical achieved not did (0.71; p=0.57) fluctuation or 0.21-2.39; p=0,057) were outcome favorable with (diagram1). associated 27(16,9%) Factors outpatient as which treated from were evolution afavorable presented [email protected], [email protected] QC, Canada; Canada; QC, PERIAPICAL ABSCESSES: A 10-YEAR ANALYSIS IN A PAEDIATRIC INPATIENT CAREUNIT LIKELY BACTERIAL ACUTE CERVICAL LYMPHADENITIS INCHILDREN:FACTORS PREDICTIVEOFFAVORABLE Philippon Results: adecision create to order in children in LBACL of management the in outcome favorable with associated factors clinical To identify Purpose: the presence of leucocytosis and unfavourable evolution (p =0.036). (p evolution unfavourable and leucocytosis of presence the Results: population. apaediatric in abscesses periapical of factors risk severity identify and features clinical-epidemiological Analyze Purpose: Karina Deshaies Poliquin KarinaDeshaies Laval, Québec, QC, Canada; Canada; QC, Québec, Laval, This retrospective observational study was based on the review of medical records of patient from 1 month to 18 to 1month from patient of records medical of review the on based was study observational retrospective This Methods: and Materials Retrospective observational and analytical study of paediatric inpatients in a Portuguese hospital with the diagnosis diagnosis the with hospital aPortuguese in inpatients paediatric of study analytical and observational Retrospective Methods: and Materials / OP3: 2 216 /OP3: ID: 35(21,1%). in 31(18,7%). in performed was 68(41,0%) drainage Overall, patients Surgical tomodensitometry cervical and 139(83,7%)in patients in 85.1%, and 80.4% were submitted to dental procedure (68.3% exodontia). All hospitalized patients started intravenous antibiotics, 30.9% in in 30.9% antibiotics, intravenous started patients hospitalized All exodontia). (68.3% procedure dental to 85.1%,in submitted 80.4% were and / OP3: 1 181ID: /OP3: Introduction: Introduction: bilateral cervical lymph node involvement, congenital malformation, immunodeficiency or underlying neoplasia. Favorable evolution was was evolution Favorable neoplasia. underlying or immunodeficiency malformation, congenital involvement, node lymph cervical bilateral official no as surgery to antibiotherapy from widely vary may and advice expert on relies (LBACL) mainly lymphadenitis cervical acute bacterial █ Department of Pediatrics, Centre-Mère-Enfant-Soleil, CHU de Québec - Université Laval, QC, Canada; Canada; QC, Laval, -Université Québec de CHU Centre-Mère-Enfant-Soleil, Pediatrics, of Department OP3: PRESENTATIONS: ORAL 3 SESSION █ Time: OP3: PRESENTATIONS: ORAL 3 SESSION This study included 94 patients (median age of 11.0 years, 52.1% female), with a median hospitalization time of 6 days (maximum 27 27 (maximum 6days of time 11.0 of age (median 52.1% hospitalization years, patients 94 amedian female), with included study This Our final study cohort was composed of 166 patients with a mean age of 4,5 years (3,5SD) and 62% male. Ultrasound was obtained obtained was Ultrasound male. 62% and (3,5SD) years of 4,5 age mean a with of patients 166 composed was cohort study final Our 5 20 9 , Josée-Anne Gagnon , Josée-Anne Thursday, 07/Dec/2017:4:30pm-6:30pm•Location:Turin Hall t h Older patients without prior antibiotic use, those with lower absolute white blood cell count and no purulent material on ultrasound ultrasound on material purulent no and count cell blood white absolute lower with those use, antibiotic prior without patients Older

E , Andreia Ribeiro, Isabel Ayres Pereira, Joana Tenente, Marta Vila Real, Sónia Viegas Sónia Real, Vila Marta Tenente, Joana Pereira, Ayres Isabel Ribeiro, , Andreia Cervical lymphadenitis is frequent in the pediatric population and usually the result of infectious agents. Management of likely likely of Management agents. infectious of result the usually and population pediatric the in frequent is lymphadenitis Cervical Oral diseases are an increasingly health problem in the paediatric population with important morbidity and health care costs, costs, care health and morbidity important with population paediatric the in problem health increasingly an are diseases Oral 5 D Department of Surgery, Centre-Mère-Enfant-Soleil, CHU de Québec - Université Laval, QC, Canada; karina.deshaies- Canada; QC, Laval, -Université Québec de CHU Centre-Mère-Enfant-Soleil, Surgery, of Department I T 1 I O 7 3 Population Health and Optimal Health Practices Research Unit, Centre de recherche du CHU de Québec Université Université Québec de CHU du recherche de Centre Unit, Research Practices Health Optimal and Health Population N Topics: Topics: 1 General Pediatrics, Infectious Diseases &Vaccines Diseases Infectious Pediatrics, General General Pediatrics, Infectious Diseases &Vaccines Diseases Infectious Pediatrics, General , Laurence Arsenault-Blanchard Laurence , 4 Department of Emergency Medecine, Centre-Mère-Enfant-Soleil, CHU de Québec - Université Laval, Laval, -Université Québec de CHU Centre-Mère-Enfant-Soleil, Medecine, Emergency of Department 1 CONFERENCE PROGRAMME ABSTRACTS 1 , Alexandre Marceau Alexandre ,

ORAL PRESENTATIONSORAL 2 , Richard Belanger Richard, 2 Faculty of Medecine, Medecine, of Faculty 3 , Simon Berthelot Simon , 4 , Daniel Daniel , 63

Abstracts 64 Health Sciences 3 University of South Carolina Arnold 2 ORAL PRESENTATIONS 3

1 , Cüneyt Akyurt 2 , Basim Asmar 2 , Şirin Güven 2 Health Sciences University, Ümraniye Training & Research Hospital, Turkey; 2 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE , Xiaoming Li 1 Allergy, Immunology & Pulmonology Infectious Diseases & Vaccines , Ayşen Cetemen 1 Topics: Topics: N 7 O I 1 T I D There are so many developed tools for detecting asthma control in children. Childhood asthma control test (C-ACT) that is Annual vaccination of children against seasonal influenza with trivalent inactivated influenza vaccine (TIV) has shown to be E

Although C-ACT is a reliable and validated tool in detecting asthma control, there are some discrepancies when the patients Seasonal TIV uptake was significantly higher H1N1-infected in group.the The finding suggests that the practice of yearly To the author’s To knowledge, this is the first study of periapical abscesses in paediatric inpatients. The scarcity of medical records h , HowardFischer t 1 9 20 This was a retrospective case-control reviewed study. We the hospital’s electronic medical records of all polymerase chain reaction– We identified We 353 polymerase chain reaction–confirmed H1N1 cases and 396 matching control subjects. group, H1N1 Among the For the reliability test of C-ACT cronbach’s alpha value was found 0,883. Mean C-ACT score of the patients whose asthma control OP3: ORAL PRESENTATIONS: SESSION 3 ORAL PRESENTATIONS: OP3: Orhangazi Country Hospital, Turkey; Wayne State University School of Medicine, Children’s Hospital of Michigan, Detroit, MI, USA; beneficial and it has been recommended in many developed countries, primarily the United States and someEuropean countries. this However, help physicians for evaluating the disease status and therapy choices. heterotypic immuneresponse and possible protection against future pandemic strains. ID: 276 / OP3: 4 Introduction: heterotypic immunity against the pandemic recent novelstrain. H1N1 Therefore, children and other immunologically naive individuals would be Introduction: influenza infection. influenza immunity, which closely resembled natural immunity than did the use of inactivated virus vaccines. Similarly, live attenuated intranasal vaccine health problem should be emphasized among Paediatricians to promote oral health and prevent oral diseases. / OP3: 3 ID: 114 Methods: Material and Methods: years patients 164 were enrolled aged 4 -11 in the study. All the patients and their caregivers’ fulfilled10- C-ACT the period from October 2009, to January The immunization 2010. records infected of the group H1N1 and an age-, gender-, and race-matched Results: Purpose: hypothesized We that a possible unintended consequence of the practice of yearly TIV vaccination might be the lack of induction of Results: Purpose: The aim of this study is, to evaluate reliability and validity of C-ACT in detecting asthma control in children by comparing C-ACT 202/353 cases (57%) received a total doses of 477 of seasonal TIV compared with in the 218/396 control (55%) group who received a total of for some variables made difficult the identification of significant association, reinforcing the importance of research on this area. This public POSSIBLE IMPACT OF YEARLY CHILDHOOD VACCINATION WITH TRIVALENT INACTIVATED INFLUENZA VACCINE VACCINE INFLUENZA INACTIVATED WITH TRIVALENT CHILDHOOD VACCINATION YEARLY OF POSSIBLE IMPACT vaccination with TIV might have negatively affected the immune response to the novel strain. pandemic Given H1N1 the rarity of pandemic Conclusion: Conclusion: wild-type influenza A viruses vaccinationor with live attenuatedvaccine strains produced a more effective, broader heterotypic(cross-protective) Conclusion: yearly practice may have an unintended effect. Several animal studies, mostly in mice and ferrets, have demonstrated that infection with either novel influenza viruses and the high predictability of seasonal influenza occurrence, the practice of yearly influenza vaccination should be mean C-ACT score of the patients whose asthma control status is partly controlled are significantly higher from uncontrolled 0.01). p< (p:0.001; School of Public Health; [email protected] It is seen that when the C-ACT total score equal and above 22 the test sensitivity spesifity was 86%, 11 was 73,44% and the accuracywas (TIV) ON THE IMMUNE RESPONSE TO THE PANDEMIC STRAIN H1N1 THE PANDEMIC RESPONSE TO (TIV) ON THE IMMUNE Oral Presentation status is well controlled according to GINA guideline criteria are significantly higher from uncontrolled and partly (p:0.001) controlled (p:0.001); scores and GINA criteria. University, Yüksek İhtisas Training & Research Hospital, [email protected] Turkey; COMPARISON OF GLOBAL INITIATIVE FOR ASTHMA GUIDELINE CRITERIA AND CHILDHOOD ASTHMA CONTROL ASTHMA AND CHILDHOOD GUIDELINE CRITERIA ASTHMA FOR INITIATIVE OF GLOBAL COMPARISON Oral Presentation When stratified into 4 different age groups, the only statistically a significant increase of seasonal TIV ageuptakeH1N1 18 group to was in the 1 1 date immunization status was significantly grouphigher 204/353 H1N1 in the (58%) than in the control 190/396group (48%; P= .008) developed for detecting asthma control in children years isone aged of these 4-11 tools. continued. the However, use of the live attenuated intranasal vaccine, as opposed may allow for to TIV, the desirable development of a vigorous confirmed cases of influenzanovel 2009H1N1 in children 6 months 18 years to old who were seen at the Children’s Hospital of Michigan during control group were reviewed using the Michigan Care Improvement Registry to verify their respective seasonal influenzavaccination status. compared between total C-ACT scores and GINA guideline criteria. guideline criteria and pulmonary function test was performed. C-ACT scores Total calculated at the end of the study. Asthma control status evaluated individually for asthma control. It is not true to detect asthma control by only using this test. But it must be accepted as a tool, which (LAIV) in animals as well as in young children has shown a superior relative efficacy when compared with inactivated influenza vaccine. at higher risk of becoming infected novel pandemic with the H1N1 strain than those who have developed heterotypic immunity through previous 76,22% (the highest in detecting rate) controlled asthma. 435 doses. Seasonal TIV uptake was significantly grouphigher 477/548than(87%) in theH1N1 in the control (P = .017). group, 435/532(81%) 48 compared months: (95%) 91 in the with same (85%) 81 control agegroup Also, = .02). (P the number of vaccinees who had an overall up-to- Ahdi Amer Yezdan Akman Akyurt Akman Yezdan TEST FOR DETECTING ASTHMA CONTROL ASTHMA TEST FOR DETECTING 15 minutes15 before the clinical visit. In clinical visit patients asthma control status was determined, blinded to C-ACT scores, by using GINA

Abstracts The quality of life inventory results are shown in Table 2 in both parent and children reports. In our study, in three categories of quality of life life of quality of categories three in study, our In reports. children and parent Table in both 2in shown are results inventory life of quality The

Ana Rita Araújo Rita Ana Table 1: auscultation and 27% had pale skin. 14% presented either polypnea or respiratory distress signs. 13% of the cases had a normal physical physical anormal had 13% cases the of signs. distress respiratory or polypnea either 14% skin. presented pale had 27% and auscultation movements (100%), respiratory by pain chest aggravated were symptoms presentation Main cases. the of 80% in activity physical with associated and the total score of both report and my / my child’s neuromuscular disease score of both report (p<0.05). FEV1 and FVC values were were values FVC FEV1 and (p<0.05). report both of score disease neuromuscular my /my child’s and report both of score total the and examination .100% of the cases were unilateral, 67% of them in the left lung. 73% of the cases were spontaneous primary pneumothorax. pneumothorax. primary spontaneous were cases the of 73% lung. left the in them of 67% unilateral, were .100% cases the of examination pulmonary on sounds respiratory diminished had 80% 98,4%. of was O2 average (40%). (47%)(53%), admission On dyspnea cough and (FEV1), forced vital capacity (FVC), FEV1/FVC and peak expiratory flow (PEF). The quality of life was assessed using the Pediatric Quality of of Quality Pediatric the using assessed was life of quality The (PEF). flow expiratory (FVC), peak FEV1/FVC and capacity (FEV1), vital forced of approximately 1 in 3,600 to 6,000 live births. Dystrophin deficiency in patients with DMD causes progressive degeneration of skeletal muscles, muscles, skeletal of degeneration progressive causes DMD with patients in deficiency Dystrophin births. live 6,000 to 3,600 1in approximately of on more than 40%. 7% of the cases resolved spontaneously, 20% with supplementary oxygen and 33% with thoracic drainage. 33% of the patients patients the of 33% drainage. thoracic with 33% and oxygen supplementary with 20% spontaneously, resolved cases the of 7% 40%. than more on consumption.27% had Asthma and 13% Allergic rhinitis. 20% had personal history of pneumothorax. Pneumothorax development was not not was development Pneumothorax pneumothorax. of history personal had 20% rhinitis. 13% and Allergic Asthma had consumption.27% other muscle groups. As we have seen in our work, respiratory functions could affect quality of life. Assessment of the quality of life, together together life, of quality the of Assessment life. of quality affect could functions respiratory work, our in seen have we As groups. muscle other 0.05). (p> parameters life of quality the of any and FEV1/FVC value the between found was association significant No <0.05). (p score total report parental the with only correlated old of age admitted in our department between 01/01/2012 and 30/06/2017, with any ICD-9 diagnosis of Pneumothorax at time of discharge. discharge. of time at Pneumothorax of 01/01/2012 diagnosis between 30/06/2017, ICD-9 any and with department our in admitted age of old 1 1 respiratory and cardiac muscles and functional skills with continuous degeneration of muscle fibrils and these affect quality of life and duration. and life of quality affect these and fibrils muscle of degeneration continuous with skills functional and muscles cardiac and respiratory Presentation Oral Presentation Oral training. muscle of effects the examine and strengths muscle respiratory evaluate to needed are studies rare entity on pediatrics. Due to its broad clinical presentation and prognosis pediatricians must be aware of it and prepared to manage it. manage to prepared and it of aware be must pediatricians prognosis and presentation clinical broad its to Due pediatrics. on entity rare needed thoracic surgery for definitive treatment. Patients were discharged on average 6 days after admission. Recurrence occurred on 27%. on occurred Recurrence admission. after days 6 on average discharged were Patients treatment. definitive for surgery thoracic needed with respiratory evaluation from an early period, and the importance of seeing progress in this evaluation result. More detailed and follow-up follow-up and detailed More result. evaluation this in progress seeing of importance the and period, early an from evaluation respiratory with Conclusion: patient’s weight was 57.4 kg and average BMI -percentile of 25.5%. (-1.1 SD). 40% had personal history of tobacco/tobacco and cannabinoids cannabinoids and tobacco/tobacco of (-1.1 25.5%. of history 57.4 was -percentile personal SD). had BMI weight average 40% kg and patient’s EFFECT OFRESPIRATORY FUNCTIONSONQUALITY OFLIFEINCHILDRENWITHDUCHENNEMUSCULARDYSTROPHY postural problems. Respiratory parameters should be taken into account earlier, as this group of patients may have worse progressions than than progressions worse have may patients of group this as earlier, account into taken be should parameters Respiratory problems. postural PNEUMOTHORAX INPEDIATRICS: THEEXPERIENCEOF A PORTUGUESEHOSPITAL Pneumothorax size classification varied with the method used to calculate it. CT scan was performed on 80% of the patients with air bubbles found found bubbles air with patients the of 80% on performed was scan CT it. calculate to used method the with varied classification size Pneumothorax Portuguese Portuguese hospital. Demographics were recorded. Respiratory functions were assessed by measuring the parameters of forced expiratory volume in 1 second 1second in volume expiratory forced of parameters the measuring by assessed were functions Respiratory recorded. were Demographics Ertugrul Safran Ertugrul Results: Results: The aim of our study is to evaluate respiratory functions in patients with DMD and to examine their impact on quality of life. of quality on impact their examine to and DMD with patients in functions respiratory evaluate to is study our of aim The Purpose: Data regarding the patient, clinical presentation, treatment and follow-up were collected and analyzed. and collected were follow-up and treatment presentation, clinical patient, the regarding Data To characterize the patients, disease, treatment and outcome of Pneumothorax cases diagnosed in a Pediatrics department of a a of department aPediatrics in diagnosed cases Pneumothorax of outcome and treatment disease, patients, the To characterize Purpose: Life Inventory Neuromuscular Module (PedsQL-3.0). Module Neuromuscular Inventory Life FranciscoRibeiro-Mourão Local de Saúde do Alto Minho, Hospital de Santa Luzia, Portugal; [email protected] Portugal; Luzia, Santa de Hospital Minho, Alto do Saúde de Local The study conducted with children, DMD diagnosis, ages between 8-12 years, have sufficient cognitive level. level. cognitive 8-12 sufficient have years, between ages diagnosis, DMD children, with conducted study The Methods: and Materials We present a retrospective observational study including all patients with more than 28 days and less than 18 years 18 than years less and days 28 than more with patients all including study observational aretrospective We present Methods: and Materials Introduction: index were calculated as 26,2 kg/m2. The respiratory function values of the children evaluated within the scope of our study are shown in Table in 1. shown are study our of scope the within evaluated children the of values function respiratory The kg/m2. 26,2 as calculated were index inventory, children report scores were higher than parent report scores (Table 2). A significant correlation was found between the PEF score score PEFthe between found was correlation (Table 2). Asignificant scores report parent than higher were scores report children inventory, / OP3: 5 /OP3: 221 ID: Introduction: / OP3: 6 /OP3: 156 ID: PEF: Peak Expiratory Flow PEF: Expiratory Peak Capacity, Vital FVC:Forced 1second, in volume expiratory FEV1: forced m: Pediatrics Department, Unidade Local de Saúde do Alto Minho, Hospital de Santa Luzia, Portugal; Portugal; Luzia, Santa de Hospital Minho, Alto do Saúde de Local Unidade Department, Pediatrics Bezmialem Vakıf University, Turkey; Vakıf University, Bezmialem Respiratory Parameters PEF FVC FEV1 FEV1/FVC OP3: PRESENTATIONS: ORAL 3 SESSION mean, sd: standart deviation, DMD: Duchenne Muscular Dystrophy, Dystrophy, Muscular Duchenne DMD: deviation, standart sd: mean, Respiratory Function Test Results of DMD Patients DMD of Test Results Function Respiratory 15 cases of pneumothorax in 11 different patients were identified. 80% of them were male with an average age of 16.7 years. Average of age Average 16.7 years. an average with male were them of 80% identified. were patients 11 in different pneumothorax of 15 cases A total of 20 children were evaluated who meet the inclusion criteria. The mean age of the patients was 9,5 years and the body mass mass body the and years 9,5 was patients the of age mean The criteria. inclusion the meet who evaluated were children 20 of Atotal 20 9 t h DMD patients could experience ambulatory problems in early period and have severe respiratory problems with accompanying accompanying with problems respiratory severe have and period early in problems ambulatory experience could patients DMD

E Duchenne Muscular Dystrophy (DMD) is a hereditary disease with recessive inheritance due to the X-chromosome, with a prevalence aprevalence with X-chromosome, the to due inheritance recessive with disease ahereditary (DMD) is Dystrophy Muscular Duchenne Pneumothorax represents the existence of air in the pleural space and can, in extreme cases, lead to pulmonary failure. It is a a is It failure. pulmonary to lead cases, extreme in can, and space pleural the in air of existence the represents Pneumothorax D I T 1 1 I 1 O 7 Kamer Unal Eren Unal , Kamer N Topics: Topics: - 1,46±0,54 1,28±0,42 (m±sd) 2,56±1,20 Liter General Pediatrics, Allergy, Immunology &Pulmonology Immunology Allergy, Pediatrics, General Allergy, Immunology & Pulmonology, Emergency Pediatrics Emergency &Pulmonology, Immunology Allergy, 1 , Ariana Teles CONFERENCE PROGRAMME ABSTRACTS 1 2 , Aysel Yıldız , Aysel Marmara University, Turkey; [email protected] University, Marmara 74,5±13,2 71,3±12,7 (m±sd) Percaetage (%) Percaetage 62,53±21,48 90,8±8,74 1 , Vera Gonçalves Vera , 2 , Hulya Nilgun Gurses Nilgun , Hulya 1 , Francisca Martins Francisca ,

Table 2: M: Total Score Total About my/my child’s child’s my/my About neuromuscular disease Categories Communication Family resources Family mean, ss: standard deviation standard ss: mean, Pediatric Quality of Life Inventory Scores Inventory Life of Quality Pediatric 1 1 , Ana Luísa Vaz Luísa Ana , ORAL PRESENTATIONSORAL 75,48±10,6 (m±sd) Parent Report Parent 62,25±18,27 67,68±20,42 69,32±15,28 2 Pulmonology Department, Unidade Unidade Department, Pulmonology 1 , Rui Nêveda Rui , 2 , Helena Ramalho Helena , 77,2±8,35 73,82±13,4 (ort±ss) 71,68±16,82 Patient’s Report 65,42±18,55 65 1 ,

Abstracts 66 ORAL PRESENTATIONS

ABSTRACTS CONFERENCE PROGRAMME CONFERENCE Child Mental Health, Preterm Infant Child Mental Health, Neurology Child Mental Health Mental Child Topics: Topics: Topics: N , Irawan Mangunatmadja, Pustika Amalia, Eka Laksmi, Bambang Tridjaja, Bernie Endyarni Medise 7 O I 1 T I D Preterm children with ASD have worst outcome compared to term possibly due to co-existed CNS lesions. In term population The experience of traumatic stress during development can lead to a broad spectrum of long-term cognitive and emotional Autistic Spectrum Disorder affects (ASD) patient through out his life interfering with his ability to interact and communicate. ASD E

The limited work-force available to treat the vast numbers of youth exposed to trauma require that therapists work in collaboration Despite rare on pediatric age, Pneumothorax is a respiratory emergency and physicians should be aware of it. Clinical h t 9 20 CCT is a structured, multi-modal intervention designed to reduce posttraumatic stress, depression, and anxiety in children chronically Dr. Carrion Dr. will detail the development including of CCT, presenting results from a randomized controlled trial and introducing a new A total of 38 ASD cases were analyzed years of age. Prematurity up to 11 history Boys (81.57%) 31/38 (27≤GA≤35 (28.9%). had wks) 11/38 OP3: ORAL PRESENTATIONS: SESSION 3 ORAL PRESENTATIONS: OP3: been identified as playing a role in theexecutive function, memory and emotion regulation of youth with CortisolPTSD. secreted during periods ID: 295 / OP3: 8 Introduction: ID: 164 / OP3: 9 Introduction: ID: 117 / OP3: 7 ID: 117 had improved in all cases. population Term had better outcome vs. 36.36%), compared vs. self 18.18%), care (51.85% to preterm in gazing(57,14% improved contact eye had 20/38 children (52.63%) although only had 10.52% gained good social interaction skills. Interaction with family members laboratory has demonstrated alterations on brain key regions of youth with The PTSD. prefrontal cortex, hippocampus and amygdala have Methods: Methods and Materials: Retrospective analysis of medical follow-up records of children with ASD regarding clinical parameters such as Purpose: There is a growing need for a manualized treatment aiming to increase youth insight into how an individual’s history of exposure to trauma may relate to current emotional experiences and how these in turn may be linked to maladaptive behaviors. In view of this need, Cue Results: treatment outcome project that utilizes functional near infra-red spectroscopy to assess (fNIRS) improvement in cortical function. Instructions there is an initial improvement in gazing but in the long run there remain problems with social interaction and a lifelong need for supervision. In Purpose: study a group To of children with ASD in view of their initial clinical signs and their development after early intervention, to compare Results: Effrossine Tsekoura LONG TERM CHARACTERISTICS OF AUTISTIC SPECTRUM DISORDER IN PRETERM COMPARED TO TERM TO IN PRETERM COMPARED AUTISTIC SPECTRUM DISORDER LONG TERM CHARACTERISTICS OF presence of CNS abnormalities. prevalence has been increased over the years and in the preterm population it is referred as 2 fold higher than term. With early intervention punctuate white matter lesions, 1/7 hypoxia, 1/7 microcephaly). ADHD co-morbidity had 13/38 children In (34.2%). term population mean age at first presentation is broad and the typical symptoms and signs of respiratory distress may not be present. Different treatment options can be preterm and term subgroups and to spot co-morbidities that affect my the initial diagnosis or outcome itself. Centered Therapy (CCT) was developed. CCT is designed to empower children to become their own agents of change. By addressing the impact of allostatic load, educating youth and Conclusion: with primary physicians and others through dissemination of effective interventions. will be provided on how to use this manual, including an outline of the complete course individual of CCT, session outlines, summaries, forms Conclusions: Cynthia Centauri Conclusion: Stanford University, United States of America; [email protected] Oral Presentation Oral Presentation some patients will be able to follow an independent life, although in many others severity of the diseasewill have a lifelong negative impact. COGNITIVE FUNCTION IN CHILDREN WITH THALASSEMIA MAJOR COGNITIVE FUNCTION IN CHILDREN WITH THALASSEMIA CUE-CENTERED THERAPY FOR YOUTH WITH POSTTRAUMATIC STRESS DISORDER (PTSD) SYMPTOMS STRESS DISORDER YOUTH WITH POSTTRAUMATIC FOR CUE-CENTERED THERAPY Oral Presentation With detailed behavioral evaluation suspicion of diagnosis and early intervention can be made before months 18 of age. consequences. These may result in academic underachievement, depression, anxiety, and post-traumatic stress disorder as well (PTSD), of chronic stress may play a significant role. caregivers on the conditioning process that occurs through repeated exposure to trauma, employing insight-oriented strategies and visual icons, one third of cases the presence of coexisted ADHD might affect outcome in either way. of age. Mean intervention interval and follow-up time Mean years). was 5.6 maternal years (max 11 and paternal age at conception was 35.22 yrs (r independentcommunicative school and speech vs. 18.18%), parental entry (37.03% interaction (33.33% vs. vs. 36.36%). 18.18%), Worst (77.77% outcome in total had 54.54% in preterm % in vs. term 3.7 subgroup. gazing, verbal and non verbal communication, imaginary repetitive play, behaviors, social interaction, self care, ability to school entry and exposed to interpersonal violence. By incorporating diverse psychoeducational approaches with evidence-based treatments for childhood trauma, evaluation and diagnosis months). In the was 30.5 preterm months subgroup, (r=17-60 diagnosis and early intervention was made before months 12 as acceleration or increased severity of other medical conditions, such as asthma, heart disease and substance abuse. Research in our and utilizing a physiological approach, CCT is a unique protocol that builds upon the greatest strengths of its predecessors. and take home assignments. and girls 7/38 (18.42%). CNS disordersand girls (18.42%). (63.63%) 7/38 preterm recorded children in 7/11 (3/7 VP-SHUNT for post-hemorrhagic hydrocephalus, 2/7 Victor Gerard Carrion assumed, based on each individual case. A high recurrence rate is found and a close follow-up is needed. Asklepieion General Hospital Athens Greece, Greece; [email protected] 19-45 yrs) and 38.58 yrs 22-61 (r yrs) respectively. Higher education degree had 36.36% of mothers of fathers. and 27.27% After early intervention

Abstracts 18 terminated fetuses autopsy showed a minor CHD. Most were terminated due to other anomalies, but 7 fetuses had no anomalies aside from from aside anomalies no had 7fetuses but anomalies, other to due terminated were CHD. Most aminor showed autopsy fetuses 18 terminated VALIDITY OFPRENATAL DIAGNOSIS OFMAJORCONGENITAL HEARTDISEASEISINCREASING Jørgensen abnormal for children to walk on their toes for a short period when they first begin to ambulate, prolonged toe walking is not a component of of component a not is walking toe prolonged ambulate, to begin first they when period ashort for toes their on walk to children for abnormal existed between the thalassemia patients IQ and pre-transfusion Hb level (p<0.05). level Hb pre-transfusion and IQ patients thalassemia the between existed WALKING: A CASEREPORT (p=0.7213). Autopsy reports were obtained on 60.3% of the terminated fetuses. The proportion of correct diagnosis increased throughout throughout increased diagnosis correct of proportion The fetuses. terminated the of 60.3% on obtained were reports (p=0.7213). Autopsy of Obstetrics and Gynaecology, Aalborg University Hospital, Denmark; Denmark; Hospital, University Aalborg Gynaecology, and Obstetrics of children and terminated fetuses diagnosed prenatally with a major CHD. We defined major CHD as lesions that usually necessitate intervention intervention necessitate usually that lesions as CHD major CHD. We defined amajor with prenatally diagnosed fetuses terminated and children diagnosis. prenatal the of detected (for instance, cerebral palsy (CP), Duchenne’s muscular dystrophy, congenitally short Achilles’ tendon, or autism). While it’s not not it’s While autism). or tendon, Achilles’ short congenitally dystrophy, muscular (CP), palsy Duchenne’s cerebral instance, (for detected cardiac examination when TOP, as misinterpretation may have severe consequences. severe have may TOP, when misinterpretation as examination cardiac inversus. situs had one and autopsy, at found lesion mild relatively the from expected than condition diagnosis reached 95% in 2013. 14 terminated fetuses had a normal cardiac evaluation at autopsy; however, all had associated anomalies. In In anomalies. associated however, had all autopsy; at evaluation cardiac anormal had fetuses 2013. in 95% 14 terminated reached diagnosis 1 1 Presentation Oral saturation, compliance to chelation, and electroencephalography test) electroencephalography and chelation, to compliance saturation, COMBINED TREATMENT WITHKINESIOTAPE AND SOFTTISSUE MOBILIZATION ONCHILDWITHIDIOPATHIC TIPTOE- reported about cognitive function in children with thalassemia major. There has been no research about cognitive functions in children with with children in functions cognitive about research no been has major. There thalassemia with children in function cognitive about reported shortly after birth. Major CHD accounts for 30% of infant deaths due to congenital malformations (Rosamond et al. e69-171) motivating vigilant e69-171) al. vigilant et (Rosamond motivating malformations congenital to due deaths infant of 30% for accounts CHD Major birth. after shortly University, Department of Physical Medicine and Rehabilitation, Istanbul, Turkey; [email protected] Istanbul, Rehabilitation, and Medicine Physical of Department University, nervous system (CNS) disorders, or serious comorbidities. serious or (CNS) disorders, system nervous maintained between 9 and 10 g/dL to prevent cognitive dysfunction. Further study is suggested to explore the factors related to cognitive cognitive to related factors the explore to suggested is study Further dysfunction. cognitive 10 prevent to 9and g/dL between maintained Presentation Oral normal development. The aim of this study was to investigate the effect of combined treatment for a child with Idiopathic tiptoe walking (ITW). walking tiptoe Idiopathic with achild for treatment combined of effect the investigate to was study this of aim The development. normal was 88.8 (±16.91). Subjects in this study had abnormal IQ score prevalence 2.7 times greater and experienced an average IQ score decrease decrease score IQ average an experienced and greater 2.7 times prevalence score IQ abnormal had (±16.91). study 88.8 was this in Subjects score IQ (±SD) total of Mean retarded. mentally moderate were subjects 2/70 and retarded mentally 37.1%.was mild were 70 subjects per Six transferrin ferritin, level, haemoglobin pre-transfusion education, patients transfusion, of duration (age diagnosis, at major thalassemia with Conclusion: Center Cipto Mangunkusumo Hospital. Intelligence quotient assessed using Wechsler intelligence scale for children test-III (WISC-III). (WISC-III). test-III children for scale intelligence Wechsler using assessed quotient Intelligence Hospital. Mangunkusumo Cipto Center Chronic anaemia and iron overload in thalassemia major lead to several risk factors including cognitive problems, but there are only few studies studies few only are there but problems, cognitive including factors risk several to lead major thalassemia in overload iron and anaemia Chronic within the first year of life. Postnatal findings and autopsy reports were compared with diagnoses made in utero. in made diagnoses with compared were reports autopsy and findings Postnatal life. of year first the within ultrasound had shown signs of poor prognosis that was not evident at autopsy. 2 had developed hydrops foetalis suggesting a more serious serious amore suggesting foetalis hydrops developed 2had autopsy. at evident not was that prognosis poor of signs shown had ultrasound Conclusion: prenatal diagnosis may be reliable. be may diagnosis prenatal the that so out carried are results screening on audits regular that crucial is CHD. It major of majority vast the detect to screening prenatal Electroencephalogram (EEG) results were analyzed by a pediatric neurology consultant. Subjects were excluded if they had epilepsy, central central epilepsy, had they if excluded were Subjects consultant. neurology apediatric by analyzed were (EEG) results Electroencephalogram Faculty of Medicine University of Indonesia, Ciptomangunkusumo Hospital, Indonesia; [email protected] Indonesia; Hospital, Ciptomangunkusumo Indonesia, of University Medicine of Faculty function in children with thalassemia major. thalassemia with children in function 83.8%, p<0.0001). The lowest rates were found in CoA (60.0%) and AVSD (60.0%). If these CHDs were disregarded the proportion of correct correct of proportion the disregarded were AVSD (60.0%) CHDs CoA and in (60.0%). these found If were rates lowest The p<0.0001). 83.8%, Results: children in function cognitive to related factors (2) identify to major thalassemia with children in function (1)Purpose: cognitive To investigate Indonesia. of Center Thalassemia in major thalassemia Denmark; [email protected] RebekkaLytzen Hospital, Denmark;Hospital, Hvidovre, Denmark; Denmark; Hvidovre, the study (p<0.0001) and reached 88.5% in 2013. The presence of an anomaly decreased the chances of a correct diagnosis (65.9% vs vs (65.9% diagnosis acorrect of chances the decreased anomaly an of 2013. presence in The 88.5% reached and (p<0.0001) study the validity the evaluate and CHD major diagnosed prenatally with fetuses of management the of development the illustrate to We aimed Purpose: Results: the minor CHD. One foetus from 1998 was suspected of AVSD, which turned out to be ASD and VSD. 3 had Shone’s complex in which prenatal prenatal which in complex VSD. Shone’s 3had and ASD be to out AVSD, of turned which suspected 1998 was from foetus CHD. One minor the Suheda Gozaydinoglu Suheda A cross-sectional descriptive analytic study conducted from April 2016 to April 2017 on Thalassemia 2017 2016 Thalassemia on April to April from conducted study analytic descriptive Across-sectional Methods: and Materials We conducted a nationwide retrospective study from January 1st 1996 – December 31st 2013 including all live-born live-born all 31st 2013 1st including –December 1996 January from study retrospective anationwide We conducted Methods: and Materials / OP3: 10 /OP3: 194 ID: Introduction: Introduction: Introduction: / OP3: 11 /OP3: 150 ID: by 11.2 points than the normal population. Sixty percent of EEG results were abnormal generalized background slowing activity. A correlation Acorrelation activity. slowing background generalized abnormal were EEG of results percent Sixty population. normal 11.2by the than points Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark; Denmark; Hospital, University Copenhagen Rigshospitalet, Cardiology, of Department Bezmialem Vakif University, Faculty of Health Sciences, Department of Occupational Therapy, Istanbul, Turkey; Istanbul, Therapy, Occupational of Department Sciences, Health of Faculty University, Vakif Bezmialem OP3: PRESENTATIONS: ORAL 3 SESSION A total 70 subjects with thalassemia major aged 9 to 15.5 years old performed IQ test. The prevalence of abnormal IQ score (<85) (<85) score IQ abnormal of prevalence The test. IQ performed old 15.5 9to years aged major thalassemia with 70 subjects Atotal 815 fetuses and live born children were included in this study. 57.8% were terminated, remaining stable throughout the study study the throughout stable remaining 57.8% study. this terminated, in were included were children born live 815 and fetuses 20 9 6 t h , Lars Søndergaard , Lars Our study found high prevalence of abnormal IQ test in children with thalassemia major. Pre-transfusion Hb level needs to be be to needs level Hb major. Pre-transfusion thalassemia with children in test IQ abnormal of prevalence high found study Our The validity of a prenatal major CHD is increasing, but is still low for CoA and AVSD. Special focus should be placed in the the in placed be should focus AVSD. and CoA for low Special still is but increasing, is CHD major aprenatal of validity The

E Thalassemia is the most common hereditary disorders worldwide, including Indonesia. It is proven to be a burdening disease. disease. aburdening be to proven is It Indonesia. including worldwide, disorders hereditary common most the is Thalassemia Congenital heart disease (CHD) comprises a spectrum of malformations from minor lesions to major CHD that can be fatal fatal be can that CHD major to lesions minor from malformations of aspectrum (CHD) comprises disease heart Congenital The tiptoe walking is diagnosed as idiopathic (habitual) if no signs of neurological, orthopaedic, or psychiatric disease are are disease psychiatric or orthopaedic, neurological, of signs no if (habitual) idiopathic as diagnosed is walking tiptoe The D I T 1 I O 7 1 N , Niels Vejlstrup Niels , 3 6 Fetal Medicine Unit, Department of Obstetrics and Gynecology, Aarhus University Hospital, Denmark; Denmark; Hospital, University Aarhus Gynecology, and Obstetrics of Department Unit, Medicine Fetal Topics: Topics: Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Hvidovre, Hospital University Copenhagen Gynecology, and Obstetrics of Department Unit, Medicine Fetal 1 , Berna Urkmez , Berna General Pediatrics, Management Pediatrics, General General Pediatrics General 1 1 CONFERENCE PROGRAMME ABSTRACTS ,Jesper Bjerre 2 2 , Olav Bjørn Petersen Bjørn Olav ,

5 Department of Pediatrics, Copenhagen University Hospital Hospital University Copenhagen Pediatrics, of Department 3 , Stine Leenskjold Stine , ORAL PRESENTATIONSORAL 2 Department of Paediatrics, Aarhus University University Aarhus Paediatrics, of Department 4 , James Keith Dodd Keith James , 2 Bezmialem Vakif Vakif Bezmialem 5 , Finn Stener Stener , Finn 4 Department Department 67

Abstracts 68 Department of 2 Department of 4 1,4 ORAL PRESENTATIONS , Maria Piccione 1 Laboratory for Molecular Diagnosis of Rare Diseases, Department 3

, Emanuela Salzano Emanuela , 3 , Antonino Giambona ABSTRACTS CONFERENCE PROGRAMME CONFERENCE 1 Orthopaedics Rare Diseases, Neurology Topics: Topics: , Alice Moncada N 7 O 1,2 I 1 T I D Cerebral palsy - a group of permanent disorders that are attributed to non-progressive disturbances that occurred inthe MCPH is defined as clinical homogeneous, but genetically heterogeneous, group of autosomal recessive neurogenic mitotic E

According to the literature it is considered normal for children to walk on their toes until the age of 2-3. On the other hand early Brain disorders in cerebral palsy are permanent said and – children as S.Terver with CP became The main adult goals with CP. h t Friday, 08/Dec/2017: 11:30am - 1:30pm • Location: Turin Hall - 1:30pm • Location: Turin 08/Dec/2017: 11:30am Friday, 9 20 The follow up was from 6 months to 3 years. GMFCS II-III group (7 patients): average improvement by Gate Observation Scale – OP4: ORAL PRESENTATIONS: SESSION 4 ORAL PRESENTATIONS: OP4: Time: Time: █ OP4: ORAL PRESENTATIONS: SESSION 4 ORAL PRESENTATIONS: OP4: Regional Referral Centre for Rare Genetic and Chromosomal Diseases, Villa Sofia-Cervello Hospital,Palermo, Italy.; █ began to use the so-called “Single Event Multilevel Surgery”. ID: 171 / OP3:ID: 171 12 intervention programs are significant in rehabilitation. In our case we noticed that he could continue tiptoewalking and remain this type of ID: 242 / OP4: 1 Introduction: Introduction: in his cranial MR. His family reported that he began to walk when months he was 12 old. Hehad no fixed plantar flexion contracture but we improvement points, – 5,7 (the worst improvement in – 2, two the best children). – 11 4 patients improved GMFCS IV to III, one patient IV to II. 6,8 points (the worst improvement patients – 2, the Two improved best – 10). GMFCS patients) II to III. GMFCS IV – average group (17 Materials and Methods: The early results of SEMLS were studied children on 31 underwent which amounted surgery to 35% of in 2014-2017, Mikhail Mikhovich, Leonid Glazkin Mogilev regional children’s hospital, Belarus; [email protected] Davide Vecchio Results: Purpose: The purpose of our study was to evaluate the early results of SEMLS, performed in orthopaedic department of the Mogilev Regional the total number of children who underwent surgery for treating spastic deformities of the lower extremities during this period. The determining factor of this procedure was simultaneously performing at least 2 procedures at differentlevels of the lower limbs. 20 children had spastic diplegia, Experimental Medicine, Sapienza University of Rome, Rome, Italy.; program lasted 8 weeks. Hisassessments were doneweekly, by photographs and video recordings, while he iswalking bare-foot. provide adequate care for him in a relatively short period of time. This method, especially when combined with osteotomies, is technically procedures were performed: adductor release, elongation of m.iliopsoas, hamstring elongation, rectus femoris transfer to sartorius,procedure, Strayer Achilles tendon elongation, Evans procedure, split anterior tibialis transfer, proximal varus derotational osteotomy of the hip, proximal One patient despite perfomed in age of 3 years adductor contracture release with resection of anterior branches of n.obturatorius had strong valgus hip osteotomy. The aims of surgery were different: GMFCS II-III – improvement of gait and self-service, GMFCS IV – walking training, even Conclusion: walking as behaviourally. Our results showed that combined treatment with KT and STM had positive results. When video recordings were with higher participation rates. Conclusion: Children’s hospital. Children’s Case Report: A 20 month old boy with ITW who hada positive family history of ITW was admitted to our hospital. Pathology was not detected week. Soft tissue mobilization is (STM) the application of specific and progressive manual forces with the intent of promoting changes in the with assistive devices, GMFCS V – improving of a child care and creation of the possibility to transfer him in the wheelchair. normal. According to our results KT and STM can be used as conservative method for children with ITW. Further studies should be planned myofascia, allowing for elongation ofshortened structures. STM was performed left gastrosoleus muscle grouptwice In addition a day. to KT SOLVING THE COMPLEXITY IN DIAGNOSIS OF AUTOSOMAL RECESSIVE PRIMARY MICROCEPHALY (MCPH) MICROCEPHALY PRIMARY RECESSIVE AUTOSOMAL DIAGNOSIS OF IN THE COMPLEXITY SOLVING SINGLE EVENT MULTILEVEL SURGERY IN TREATMENT OF CHILDREN WITH CEREBRAL PALSY (EARLY RESULTS) (EARLY PALSY OF CHILDREN WITH CEREBRAL IN TREATMENT SURGERY SINGLE EVENT MULTILEVEL Sciences for Health Promotion and Mother and Child Care, University of Palermo, Palermo, [email protected] Italy.; Oral Presentation Oral Presentation stereotype of musculoskeletal balance of extremities. It can improve the child’s motor activity, eliminate the severe contractures of joints and some effectiveness of conservative methods, surgicalcorrection of limb deformities is used in most cases. In recent decades most surgeons CLINICAL REPORT AND GENOTYPE-PHENOTYPE CORRELATION OF AN HOMOGENEOUS PATIENTS’ COHORT. PATIENTS’ AN HOMOGENEOUS OF AND GENOTYPE-PHENOTYPE CORRELATION REPORT CLINICAL 1 compared it was clear that he accomplished walking with a heel strike. Tightness in his left calf muscles was decreased and muscle tone was difficult and requires two teams of orthopedic surgeons and anesthesiologist who owns the technique of combined anesthesia. developing fetal or infant brain. Movement disorders are often accompanied by secondary progressive musculoskeletal problems. Despite the disorders mainly characterized by congenital reduction in head circumference with (HC) variable degree of non-progressive developmentaldelay/intellectual disability. The MCPH prevalence ranges from 1:30.000 to 1:250.000 new-borns. Due to lacking of other major dysmorphisms of surgical treatment = improving the child’s motor activity andelimination of severe limb deformities. SEMLS changes the whole pathological Presentations of Hematology for Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital,Palermo, Italy.; examined tightness his left calf muscles. Facilitation techniques of Kinesio (KT) Tape were applied to left tibialis anterior muscle three times a and STM, gentle stretching exercises were taught to his family as a home exercise program to support the treatment process. treatment Total adduction contracture after procedures. This can be seen as an indication to selective dorsal rhyzotomy or baclofen pump insertion. Parents of 7 patients GMFCS V reported an improvement in care after surgery. During follow up deterioration was not observed.

THROUGH A COMPREHENSIVE NEXT GENERATION SEQUENCING (NGS) DISEASE-CUSTOMIZED GENES PANEL. GENES PANEL. SEQUENCING (NGS) DISEASE-CUSTOMIZED COMPREHENSIVE NEXT GENERATION A THROUGH 11 – spastic11 tetraparesis. The meanage in timeof surgery was 8, the youngest child – 3, the oldest children 31 procedures. – 18. – 212 Different

Abstracts “extensive parenchymal changes with multiple blisters that replaced almost all of the lung parenchyma bilaterally”. In the absence of of absence the In bilaterally”. parenchyma lung the of all almost replaced that blisters multiple with changes parenchymal “extensive ASSESSMENT OFFUNCTIONAL CAPACITY AND RESPIRATORY FUNCTIONS INSILVER RUSSEL SYNDROME: A CASE ZNF335, PHC1, CDK6) clustered in panel was performed using Ion Torrent PGMTM Platform technology whose design target coverage was was coverage target design whose technology Platform Torrent PGMTM Ion using performed was panel in PHC1, CDK6) clustered ZNF335, as second-tiered tests, we will gain a higher diagnostic detection rate in this cohort, widening the scope of MCPH neurobiological basis. neurobiological MCPH of scope the widening cohort, this in rate detection diagnostic ahigher gain will we tests, second-tiered as and/or congenital anomalies associated, HC constitutes the most common diagnostic tool that may range from 2 to 11 SD below the mean. 11 2to mean. the from below SD range may that tool diagnostic common most the constitutes HC associated, anomalies congenital and/or Ximo Duarte Ximo (60.5%) patients involving 8/12 investigated genes (66.6%). All reported mutations have been classified as variants of uncertain clinical clinical uncertain of as variants classified been have mutations (66.6%). reported All genes 8/12 investigated involving (60.5%) patients clinical picture confirming once again how our algorithm could be considered a powerful tool for clinicians. By using MLPA and/or further functional studies studies functional further MLPA and/or using By clinicians. for tool powerful a considered be could algorithm our how again once confirming picture clinical complex cardiac abnormalities. The aim of this study was to investigate the functional capacity and respiratory functions in patients with RSS. with patients in functions respiratory and capacity functional the investigate to was study this of aim The abnormalities. cardiac complex diagnostic work-up, which included clinical, genomic, inborn errors of metabolism testing and instrumental evaluations to exclude any any exclude to evaluations instrumental and testing metabolism of errors inborn genomic, clinical, included which work-up, diagnostic diagnosis is difficult, with possible need for biopsy, but the high-resolution CT scan may show characteristic cysts and nodules. and cysts characteristic show may scan CT high-resolution the but biopsy, for need possible with difficult, is diagnosis definitive diagnosis, pulmonary transplantation was proposed. There was aggravation of respiratory function, with hypoxemia and recurrent recurrent and hypoxemia with function, respiratory of aggravation was There proposed. was transplantation pulmonary diagnosis, definitive diagnosis of pulmonary cystic disease, even in the absence of systemic manifestations. systemic of absence the in even disease, cystic pulmonary of diagnosis 1 respectively due to ASPM, CASC5 and MCPH1 compounded heterozygosity. Despite different genetic involvements, all these patients shared a common acommon shared patients these all involvements, genetic different Despite heterozygosity. MCPH1 compounded CASC5 and ASPM, to due respectively respectively for 4/32 (12.5%) and 3/32 (9.4%) cases. Furthermore, we identified 6 novel missense mutations. missense novel 6 identified we (12.5%) (9.4%) 4/32 Furthermore, for 3/32 and cases. respectively effect. damaging/deleterious a had (93.7%) variants novel 30/32 that revealed prediction pathogenicity (VUS).However, silico in significance Presentation Oral showed that the bone age was 8 years of age and that the right extremity was 5 mm shorter than the left extremity. From age 10 age 11, From to extremity. the left the than shorter 5 mm was extremity right the that and age of 8years was age bone the that showed referred to the medical genetic polyclinic when he was 10 years old and received RSS due to short stature, growth retardation, dysmorphic dysmorphic retardation, growth stature, short to due RSS received and old 10 was he years when polyclinic genetic medical the to referred learned; was following the taken, was anamnesis patient’s the When activities. running or walking long-term in evident were which fatigue rapid Presentation Oral Conclusion: neutropenic enterocolitis and reversible posterior encephalopathy syndrome. Was then medicated with cladribine, without success. Due to to Due success. without cladribine, with medicated Was then syndrome. encephalopathy posterior reversible and enterocolitis neutropenic uncertain prognosis, the patient waited for a cadaveric donor. She initiated induction with vinblastine and prednisolone, complicated by severe severe by complicated prednisolone, and vinblastine with induction initiated She donor. acadaveric for waited patient the prognosis, uncertain spontaneous recurrent presented 2014, she when November until healthy was Angola, in born female, A6-year-old report: Case A 11-year-old boy admitted to our hospital with complaints which gait disorder, low functional capacity, shortness of breath and and breath of shortness capacity, functional low disorder, gait which complaints with hospital our to A11-year-old admitted boy Report: Case Conclusion: phenotype correlation. genotype- MCPH clarify to basis; neurobiological MCPH of knowledge in advancement the to contribute to diagnosis; faster for practice pneumothorax on the right. Faced with an inconclusive diagnosis of “severe cystic lung disease”, after investigation that included pulmonary pulmonary included that investigation after disease”, lung cystic “severe of diagnosis inconclusive an with Faced right. the on pneumothorax progressive to secondary and/or iatrogenic causes of congenital microcephaly. Then, a comprehensive sequence of coding regions and splice splice and regions coding of sequence acomprehensive Then, microcephaly. congenital of causes iatrogenic and/or secondary to progressive patient has not received any treatment other than growth hormone supplementation. In evaluating the patient, The 6 Minute Walking Test Walking 6Minute The patient, the evaluating In supplementation. hormone growth than other treatment any received not has patient progressive aggravation, with global respiratory insufficiency, the patient evolved to a fatal outcome. fatal to a evolved patient the insufficiency, respiratory global with aggravation, progressive without insipidus diabetes developed However, she HCL. Cd1a for S100, and confirmed positive review, biopsy The pneumothorax. PULMONARY DISEASE AS A FORMOFPRESENTATION OFLANGERHANSCELL HISTIOCYTOSIS REPORT Português de Oncologia de Lisboa, Francisco Gentil, EPE; Gentil, Francisco Lisboa, de Oncologia de Português Fonseca, EPE, Portugal; EPE, Portugal; Fonseca, facial findings, and height difference between the extremities and first-cousin marriage between parents. Also, orthopaedic examination examination orthopaedic Also, parents. between marriage first-cousin and extremities the between difference height and findings, facial Results: To achieve a comprehensive clinical and molecular MCPH approach realizing a step-by-step guidance algorithm useful in clinical clinical in useful algorithm guidance astep-by-step realizing approach MCPH molecular and clinical To acomprehensive achieve Purpose: Rita Vieira Carvalho Vieira Rita Hence, since 12 genes have been proposed causative so far, their right monogenic assessments challenge clinicians into diagnostic arena. diagnostic into clinicians challenge assessments monogenic right far, so their causative proposed been have 12 genes since Hence, Lisboa Central, EPE; [email protected] Central, Lisboa Hikmet Ucgun Hikmet MCPH genes’ VUS were found as heterozygous variants in 25/32 events (78.1%), while multiple and compounded heterozygosities accounted accounted heterozygosities (78.1%), compounded events and 25/32 in multiple variants while heterozygous as found were VUS genes’ MCPH Missense variants were assessed using PolyPhen-2, SIFT and Mutation Taster software tools. Taster software Mutation and SIFT PolyPhen-2, using assessed were variants Missense In the last 2 years 200 children were referred to our Unit for microcephaly. Each patient completed an extensive extensive an completed patient Each microcephaly. for Unit our to referred were children 200 2years last the In Methods: and Materials Bezmialem Vakif University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Istanbul, Turkey; Istanbul, Rehabilitation, and Physiotherapy of Department Sciences, Health of Faculty University, Vakif Bezmialem 99,80%. Pathogenic status of variants identified, subsequently confirmed by Sanger sequencing, was classified according to the ACMG criteria. criteria. ACMG the to according classified was sequencing, Sanger by confirmed subsequently identified, variants of status Pathogenic 99,80%. junctions of all MPCH recognized disease causing genes (MCPH1, WDR62, CDK5RAP2, CASC5, ASPM, CENPJ, CEP135, ASPM, CASC5, CEP152, STIL, (MCPH1, CDK5RAP2, genes WDR62, causing disease recognized MPCH all of junctions lack of subcutaneous fat, constipation, increased sweating, and decreased muscle bulk. It can also be associated with impaired cognitive abilities and and abilities cognitive impaired with associated be also can It bulk. muscle decreased and sweating, increased constipation, fat, subcutaneous of lack / OP4: 2 /OP4: 239 ID: Introduction: [email protected] Introduction: involvement of other organs or systems. In the absence of conditions for transplantation with live donor, due to multisystemic involvement with with involvement multisystemic to due donor, live with transplantation for conditions of absence the In systems. or organs other of involvement he was born prematurely with a birth weight of 2180 grams and a height of 40 cm with normal delivery. The diagnosis is as follows; the boy was was boy the follows; as is diagnosis The delivery. normal with cm 40 of aheight and 2180 of grams weight abirth with prematurely born was he ID: 149 3 /OP4: ID: birth weight < 2800 grams, feeding problems, hypoglycaemia, asymmetrical body growth, late-closing fontanels, gastroesophageal reflux disease, disease, reflux gastroesophageal fontanels, late-closing growth, body asymmetrical hypoglycaemia, problems, feeding grams, <2800 weight birth biopsy, she resorted to our national health services (May 2015). She had mild dyspnea without the need for oxygen. The chest CT showed CTshowed chest The oxygen. for need the without dyspnea 2015). (May mild had She services health national our to resorted she biopsy, Pediatrics Department - Hospital Prof Doutor Fernando Fonseca, EPE, Portugal; EPE, Portugal; Fonseca, Fernando Doutor Prof -Hospital Department Pediatrics OP4: PRESENTATIONS: ORAL 4 SESSION A selected cohort of 38/200 patients (19%), matching the MCPH features was tested by NGS. We identified 32 variants in 23/38 23/38 in 32 variants We NGS. by identified tested was (19%), features MCPH the patients matching 38/200 of cohort Aselected 20 9 The use of NGS has proven to be effective and, it allowed us to assess a faster molecularly MCPH diagnosis in 3 unrelated patients patients 3unrelated in diagnosis MCPH molecularly afaster assess to us allowed it and, effective be to proven has NGS of use The t h The rare form of presentation at pediatric age delayed the diagnosis. Pulmonary HCL should be considered in the differential differential the in considered be should HCL Pulmonary diagnosis. the delayed age pediatric at presentation of form rare The

E Russell-Silver syndrome is a growth disorder characterized by slow growth before and after birth. Signs and symptoms of RSS include include RSS of symptoms and Signs birth. after and before growth slow by characterized disorder agrowth is syndrome Russell-Silver 4 In Langerhans cell histiocytosis (LCH), pulmonary involvement is uncommon in children, and the prognosis is unfavorable. The The unfavorable. is prognosis the and children, in uncommon is involvement (LCH), pulmonary histiocytosis cell Langerhans In D , Ivan Bravio , Ivan I , Busra Kepenek-Varol, H.Nilgun Gurses H.Nilgun Kepenek-Varol, , Busra T 1 I O 7 N 1 Topics: Topics: , Carlos Escobar Carlos , 3 Pathologic Anatomy Unit - Hospital Prof Doutor Fernando Fonseca, EPE, Portugal; EPE, Portugal; Fonseca, Fernando Doutor Prof -Hospital Unit Anatomy Pathologic 5 Rare Diseases, Allergy, Immunology &Pulmonology Immunology Allergy, Diseases, Rare Rare Diseases, Infant Development Infant Diseases, Rare , António Figueiredo , António CONFERENCE PROGRAMME ABSTRACTS 1 , Pedro Nunes Pedro , 1 1 , Clara Abadesso Clara , 5 Cardiothoracic Surgery Unit - Hospital de Santa Marta, Centro Hospitalar de de Hospitalar Centro Marta, Santa de -Hospital Unit Surgery Cardiothoracic

1 , Marta Moniz Marta , 2 Radiology Unit - Hospital Prof Doutor Fernando Fernando Doutor Prof -Hospital Unit Radiology ORAL PRESENTATIONSORAL 1 , Rosário Ruivo Rosário , 1 , Sérgio Ferreira 4 Pediatrics Unit - Instituto -Instituto Unit Pediatrics 2 , Rita Manso Rita , 69 3 ,

Abstracts 70 Department 4 , Finn Stener , Jasim Uddin 5 5 Sarkari Karmochari Hospital, 6 , James Keith Dodd 4 Dhaka Medical College (DMC), 4 , Md. Abid Hossain Mollah 4 Department of Pediatrics, Aarhus University 2 ORAL PRESENTATIONS , , Stine Leenskjold M Mansur Ali Medical College (MMAMC), Bangladesh, 3 2 , Nazmul Haque 3 Department of Pediatrics, Copenhagen University Hospital 5

, Rahat Bin Habib 2 , Olav Bjørn Petersen 2 Bangladesh Institute of Child Health Bangladesh, (BICH), People’s Republic dr.baki90@ of; 7 , Jesper Bjerre Jesper , ABSTRACTS CONFERENCE PROGRAMME CONFERENCE 1 Ibrahim Medical College Bangladesh, (IMC),, People’s Republic of; 5 1 7 Rare Diseases Rare Emergency Pediatrics, NICU Sir Salimullah Medical College Bangladesh, (SSMC), People’s Republic of; Mohammad Ahsanulah El Baki El Mohammad Ahsanulah 3 Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital Hvidovre, Topics: Topics: Fetal Medicine Unit, Department of Obstetrics and Gynecology, Aarhus University Hospital, Denmark; 6 , 3 1 , Niels Vejlstrup N 1 7 O I 1 T I D Major CHDs often demand surgical or catheter-based procedures in the neonatal period making early diagnosis crucial. Prenatal Cystic fibrosis(CF) is the most common life limiting recessive genetic disorder in Caucasians with an incidence of approximately E

These reports suggest that the diagnosis of CF is much delayed in Bangladeshi children which may result in failure to thrive / , Lars Søndergaard h According to our knowledge there is no study in the literature about functional capacity and respiratory functions in patients with RSS. As t , Md. Ruhul Amin 6 6 9 20 2,224 live-born children and terminated 471 pregnancies with major CHD were included. 30.2% were diagnosed prenatally, increasing OP4: ORAL PRESENTATIONS: SESSION 4 ORAL PRESENTATIONS: OP4: Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Denmark; Ad-din Women Medical College Bangladesh,(AWMC), People’s Republic of; 89 months compared with Indian Americans months 12 and 6 months among Caucasian American children and reflectsa very low the USA has been estimated to be 1 in 40000, and in the UK 1 in between 10000 to 12000. As a result of the widespread belief that Introduction: Introduction: ID: 243 / OP4: 4 identified from the NationalPatient Registry and all live-born children and terminated fetuses diagnosed with a CHD were included.We defined incidence of 1 in 80,000. ID: 193 / OP4: 5 index of suspicion for the disease even among Bangladeshi children. Majumder Materials and Methods: conducted We a nationwide retrospective study from January 1996 – December Patients 1st 2013. were 31st Bangladesh, People’s Republic of; Hvidovre, Denmark; Hospital, Denmark; Hospital,Denmark; Results: Purpose: aimed We to evaluate the effect of a prenatal diagnosis on all-cause mortality, cardiac death, as well as morbidity in patients with Rebekka Lytzen Rebekka majority of cases. The precise incidence of CF among Bangladeshis is unknown. The incidence in migrant Indian populations in Dhaka, Bangladesh, People’s Republic of; Denmark; [email protected] Denmark; rarely confirmed due to the pooravailability of facilities for diagnosis. The mean age of diagnosis among in Bangladeshi children is from 4.5 % in 1996 to 71.0% in 2013. 17.5% of fetuses with major CHDfrom 17.5% were in terminated. 2013. 4.5 % in 1996 to 71.0% This increased in 2013 from 0.6% in 1996 to 39.1% People’s Republic of; PRENATAL DIAGNOSIS OF MAJOR CONGENITAL HEART DISEASE IS ASSOCIATED WITH INCREASED MORTALITY. ASSOCIATED HEART DISEASE IS DIAGNOSIS OF MAJOR CONGENITAL PRENATAL values. In order to obtain more significant results, further studies with long term follow-up and higher participation rates are needed. Complications were defined as the occurrence of necrotizing enterocolitis, intracerebral haemorrhage, cerebral palsy, seizures, mental Conclusion: with a prenatal diagnosis and in 20.6% diagnosed postnatally (p=0.0027). CF does not occur in Indo-Bangladesh subcontinent, the disease is rarely suspected and even if it is suspected the diagnosis is Cystic fibrosis was thought to be extremely rare in Bangladesh. However published reports, reviews and commentsCF is probably indicate far morethat common in people of Bangladeshi origin than previously thought but is under diagnosed or missed in the Conclusion: major CHD was a median of 42 days compared with 37 days in the postnatal group (p=0.0018). Complications occurred of children in 27.9% major CHD as lesions that usually necessitate intervention within the first1. TableRecordsyear of life, were reviewed validateto the diagnoses. major CHD. major recorded a walking distance meters in the of 515 test result. The mean values of respiratory function were for 84% forced expiratory volume in 1 retardation, liver failure, acute kidney injury or heart failure. CYSTIC FIBROSIS (CF) IN CHILDREN OF BANGLADESH: AN EXPERIENCE WITH 71 CASES (CF) IN CHILDREN OF BANGLADESH: CYSTIC FIBROSIS Oral Presentation second (FEV1), 93%second for forced (FEV1), vital capacity and (FVC) 92% for FEV1/FVC. Oral Presentation severe malnutrition by the time the condition is eventually diagnosed — one of the bad prognostic indicators for survival. 1 1 diagnosis enables early intervention; there however, is still controversy concerning the effect of prenatal diagnosis on prognosis. of Obstetrics and Gynecology, Aalborg University Hospital, Denmark; gmail.com (p<0.0001). There was increased mortality in live-born children whose CHD had been diagnosed prenatally with a Hazard Ratio of 2.23 (HR) (p<0.0001). HR for the individual diagnoses Length is shown 1. of in stay Table in thefirst year of life for children with a prenatally diagnosed (6MWT) was used to assess the functional exercise capacity and Pulmonary Function (PFT) Testing was used to assess respiratory functions. affects other ethnic groups such as black populationwith an incidence and the Native of 1 in 17,000 American population with an approximate a result of the assessments in the present case, we found that the functional capacity decreased and the respiratory functions were at the predicted Jørgensen ARM Luthful Kabir The expected 6MWT distance was 666.55 meters, taking into consideration the age, height, weight and gender of the case, while our case 1 in 2500 children born in the United Kingdom. It is less common in African Americans in 15000) and (1 in Asian Americans It also in 31000). (1

Abstracts The three most common symptoms and signs at presentation were fever, cough and chest pain (68.3%, 56.7% and 53.3%, respectively) respectively) 53.3%, and 56.7% (68.3%, pain chest and fever, were cough presentation at signs and symptoms common most three The assessing benefits these variables should be taken into account. into taken be should variables these benefits assessing asymptomatic to causing sudden cardiac arrest. The common clinical symptoms and signs of acute myocarditis include fever, nausea and and fever, nausea include myocarditis acute of signs and symptoms clinical common The arrest. cardiac sudden causing to asymptomatic and further studied: demographics, clinical presentations, laboratory tests, findings of electrocardiogram (ECG) and echocardiography, echocardiography, (ECG) and electrocardiogram of findings tests, laboratory presentations, clinical demographics, studied: further and (Table 2). In addition, arrhythmia and left ventricular ejection fraction (LVEF) < 60% were more frequent in the EOMO group. Receiver operating operating Receiver group. EOMO the in frequent more (LVEF) were <60% fraction ejection ventricular left and arrhythmia (Table 2). addition, In with enterovirus 71; 1 with B:2 influenza with A; 4 influenza 3with including diagnoses, microbiological positive (Table 1). had 12 .Only patients counselling, termination of pregnancy, genetic testing, and optimal perinatal management and allows parents to adjust to the diagnosis. When When diagnosis. the to adjust to parents allows and management perinatal optimal and testing, genetic pregnancy, of termination counselling, characteristic (ROC) analysis showed that the best cut-off value of initial LVEF for predicting ECMO treatment was 57.5 was %. treatment ECMO LVEF predicting for initial of value cut-off best the that showed (ROC) analysis characteristic 1 Presentation Oral CLINICAL SPECTRUMOF ACUTE MYOCARDITISINCHILDREN ADMITTED TO THEPEDIATRIC EMERGENCY more common in EOMO group than non-ECMO group patients and with statistical significance (P=0.003, P=0.001 and P=0.011, respectively) P=0.011,and respectively) P=0.001 (P=0.003, significance statistical with and patients group non-ECMO than group EOMO in common more Chun-Yu Chen Conclusion: with a definite diagnosis of acute myocarditis admitted to the pediatric emergency department. The following clinical information was obtained obtained was information clinical following The department. emergency pediatric the to admitted myocarditis acute of diagnosis adefinite with Changhua, Taiwan; Changhua, parainfluenza type 2; 1 with herpes simplex virus type 1 and 1 with respiratory syncytial virus. Vomiting, weakness and seizure were reported reported were seizure and weakness Vomiting, virus. syncytial respiratory with 1 and 1 type virus simplex herpes with 2; 1 type parainfluenza vomiting, abdominal pain, shortness of breathing, tachypnea, lethargy, dysrhythmias, hypoperfusion and shock. However, it is difficult for for difficult However, is it shock. and hypoperfusion dysrhythmias, lethargy, tachypnea, breathing, of shortness pain, abdominal vomiting, prenatal diagnosis of major CHD was associated with worse prognosis. However, prenatal diagnosis permits fetal examination, parental parental examination, fetal permits diagnosis However, prenatal prognosis. worse with associated was CHD major of diagnosis prenatal primary physicians in earlier detection it and prediction the need for extracorporeal membrane oxygenation may (ECMO) may support. oxygenation membrane extracorporeal for need the prediction and it detection earlier in physicians primary (ED) visits. department emergency their of time the at presentations clinical the on based myocarditis acute with children in correctly prognosis the predict and diagnosis early an make to physicians primary from range may presentations clinical However, the children. in uncommon relatively is and events life-threatening in result possibly DEPARTMENT Results: treatment modalities, complications and long-term outcomes. long-term and complications modalities, treatment The aim of this study was to analyze clinical spectrum of acute myocarditis in children and find some helpful factors that could aid aid could that factors helpful some find and children in myocarditis acute of spectrum clinical analyze to was study this of aim The Purpose: Kaohsiung Medical University, Kaohsiung, Taiwan; Kaohsiung, University, Medical Kaohsiung From October 2011 to September 2016, we retrospectively analyzed 60 pediatric patients, aged 18 years or younger, younger, 18 or years aged patients, pediatric 60 analyzed 2016, 2011 retrospectively we September to October From Methods: and Materials / OP4: 6 /OP4: 130 ID: Introduction: 5 Department of Pediatric Emergency Medicine, Changhua Christian Children’s Hospital, Changhua, Taiwan; Changhua, Hospital, Children’s Christian Changhua Medicine, Emergency Pediatric of Department TGA Truncus Total TOF AVSD ccTGA CoA Ebstein PA-IVS PA-VSD DORV UVH IAA College of Medicine, Chang Gung University, Taoyuan, Taiwan; [email protected] University, Gung Chang Medicine, of College OP4: PRESENTATIONS: ORAL 4 SESSION Table 1. Hazard ratio for prenatal diagnosis on mortality on diagnosis prenatal for ratio 1.Table Hazard During the 5-year study period, 60 patients (32males and 28 females; mean age, 8.8±6.32 years) were diagnosed as acute myocarditis. myocarditis. acute as diagnosed were years) 8.8±6.32 age, mean females; 28 and (32males patients 60 period, study 5-year the During 20 9 t h The anticipated positive effect of prenatal diagnosis of major CHD on outcome was not established in this study. Thus in general, general, in Thus study. this in established not was outcome on CHD major of diagnosis prenatal of effect positive anticipated The

E Acute myocarditis, an inflammatory condition of the myocardium as a result of an infection, autoimmune disease or toxins, toxins, or disease autoimmune infection, an of result as a myocardium the of condition inflammatory an myocarditis, Acute D I 1,2 T 1 I O 7 , Wen-Chieh Yang , Wen-Chieh N 4 Division of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Hospital, Memorial Gung Chang Pediatrics, of Department Medicine, General Pediatric of Division Topics: 13.02 (1.27-133.88) 12.82 (2.76-59.57) 12.82 3.01 (0.26-35.03) 3.01 2.66 (0.45-15.84) 2.66 4.83 (1.71-13.66)4.83 1.32 (0.17-10.38) 1.32 1.25 (0.52-3.00) 1.25 1.38 (0.50-3.81) 1.38 1.71 (0.49-5.95) 3.27 (1.64-6.53) 3.27 2.23 (1.76-2.82) 2.23 0.98 (0.68-1.41)0.98 2.18 (0.63-7.49) Emergency Pediatrics HR CONFERENCE PROGRAMME ABSTRACTS 1,2 , Yu-Jun Chang , Yu-Jun <0.0001 p-value 0.0008 0.0030 0.0309 0.5385 0.9237 0.0011 0.6142 0.282 0.379 0.795 0.216 0.397 3 Laboratory of Epidemiology and Biostastics, Changhua Christian Hospital, Hospital, Christian Changhua Biostastics, and Epidemiology of Laboratory 3 , Han-Ping Wu , Han-Ping

4,5 ORAL PRESENTATIONSORAL 2 School of Medicine, Medicine, of School 71

Abstracts 72 Marie Claude J. , 1 0.611 0.211 0.750 0.788 0.420 1.000 0.086 0.355 0.356 0.005* 0.036* 0.003* <0.001* P-value 8.7 8.7 4.3 , Josephine , SakkalJosephine 17.4 17.4 21.7 87.0 % 30.4 30.4 30.4 30.4 73.9 52.2 78.3 1 Balamand University, Koura,Lebanon; 2 1 7 7 7 7 5 2 4 2 4 13-18 (n=23) 17 12 18 20 N ORAL PRESENTATIONS

0.0 0.0 % 10.0 20.0 20.0 50.0 40.0 40.0 30.0 60.0 40.0 30.0 60.0 60.0 7-12 1 2 5 2 4 4 4 3 6 6 3 6 0 0 (n=10) , , Georges Nicolas 1 N Age % 9.5 9.5 4.8 4.8 0.0 71.4 66.7 76.2 76.2 28.6 28.6 28.6 28.6 33.3

1-6 1 1 7 2 2 6 6 6 6 0 (n=21) 14 15 16 16 N , Issam Malouf 1 % 0.0 0.0 0.0 0.0 0.0 66.7 66.7 50.0 50.0 50.0 50.0 50.0 33.3 33.3 <0 2 4 4 2 3 3 3 3 3 0 0 0 0 0 (n=6) N % 1.7 8.3 11.7 11.7 31.7 16.7 56.7 36.7 46.7 53.3 68.3 53.3 33.3 43.3 , Georges Abi Fares ABSTRACTS CONFERENCE PROGRAMME CONFERENCE 2 1 7 7 5 Total 41 (n=60) 19 10 32 32 22 28 34 26 20 N General Pediatrics, Management Topics: Male Female Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes N , Mode AlOjaimi 7 1 O I 1 1 T I D E

We conclude We that our supplemental training program did improve some aspects of student’s pediatric skills. PE Students learned Acute myocarditis is relatively uncommon in children but may lead to prolonged admission even death.Female sex, vomiting, h t 9 20 A Cohort study was done in our university hospital “Notre Dame Des Secours”. All Med III students (27) received a supplementary After comparing the two groups, % and 39.3% 19.6 OF Med III students in the intervention group felt respectively that “if a child Demographics and clinical presentations of the patients with acute myocarditis OP4: ORAL PRESENTATIONS: SESSION 4 ORAL PRESENTATIONS: OP4: heart disease Diarrhea Fever Headache Rhinorrhea Palpitation Seizure Family history of Cough Weakness Chest pain Gender Vomiting Holy Spirit university of Kaslik-UH-Notre Dame Des Secours, Lebanon (Lebanese Republic); Tachypnea be a possible solution for better contact (p=0,007). In addition, leaving the child’s underwear on or asking parents to leave the room (p=0.025) ID: 119 / OP4: 7 ID: 119 Methods: 3-hours presentation with instructional videos regarding pediatric physical ) approach. exam (P/E This was followed by a Q/A session with Fadous Khalife Fadous Background & Objective: Physical examination is the cornerstone for correct patient diagnosis. Examination of a pediatric patient requires to implement new techniques to make children relax and comfortable. The primary results are promising. A larger scale study should be doneto better assess the advantage of implementing such a change in the Med III curriculum. Results: filled the same questionnaire: The Med III students(29) -who did not receive the supplementary presentation – after completing their pediatric DOES CLINICAL TRAINING IN PEDIATRICS IMPROVE MED III STUDENTS’ APPROACH TO CHILDREN? A COHORT A CHILDREN? APPROACH TO IMPROVE MED III STUDENTS’ TRAINING IN PEDIATRICS DOES CLINICAL Regarding the child’s comfort, the intervention group learned that” if the child is ticklish, their own hands can be used to palpate the abdomen” Conclusion: Conclusion: weakness, seizure, arrhythmia and echocardiography 60% < showed may be the LVEF important factors to indicate the patients with acute STUDY myocarditis may increase the risk of need for ECMO support. suggest We that primary clinicians should be alert and prescribe aggressivemanagement medical for patients with acute myocarditis presenting with these risk factors. Most importantly, a cut-off value of the initial detected LVEF by [email protected] rotation. used We the “Statistical Package for the Social Sciences” version (SPSS) 22 as a statistics analysis tool Oral Presentation 1 can optimize intimacy. They can just observe their walk and musculoskeletal status in case of non cooperation (p=0.030), and finally letting on their choices of clothing” (p=0.055). “Parents should not intimidate their children to answer questions nor answer for them” (p=0.087). cries it is their fault (p=0.023) and that “the child’s mother is always right until proven otherwise” % in and controls. 14.3 (p=0.000) vs 7.1% challenging if not an impossible mission for inexperienced medical students during their pediatric internship. Having a pediatric-adjusted clinical questionnaire was filled in by the same medical students, upon completion of their pediatric Med III scheduled rotation. The control group (p=0.000). questions However, concerning starting with ENT exam and using firm tone or skipping partsexamination of were not significant (p=0,063;p=0,150 respectively) Intervention group medical students learned that using gowns and explainingall the steps PE to the child may echocardiography may be less considered than 57.5% appropriate for predict need for ECMO support in children with acute myocarditis. a child play with their medical tools can help gaining their trust (p=0.003). The rest of the results was not significant: “child is not a small adult additional skills related to patient –doctor interaction. Therefore, performing an accurate and complete physical examination of a child may be a approach might be the solution. a pediatric attending and a 1-week rotation on the pediatric floor and pediatricER.Pediatric residents supervised them during daily roundsand staff meetings. Students were afterwards asked to fill a questionnaire focusing on different pediatric physicalexam skills. The same Age, years; ICU = intensive care unit. Joey El Khoury Table 1: Table *Statistically significant by theχ2 test or Fisher’s exact test when appropriated. “(p=0.237), Adults and children should not be examined the same (p= way “Trying 1.000). to estimate a child’s age” (p=0.073) and “commenting

Abstracts ASSOCIATION OFFATTY LIVERWITHSERUMGAMMA GLUTAMYLTRANSFERASE AND URIC ACID INOBESE Zagreb, Croatia; Croatia; Zagreb, and fat mass were measured. Ultra sound scan of abdomen was performed to determine fatty liver. fatty determine to performed was abdomen of scan sound Ultra measured. were mass fat and pressure blood circumference, waist GGT. UA weight, and (AST), insulin, Height, aminotransferase (ALT), aspartate alanineaminotransferase profile, lipid glucose, for drawn was blood fast, overnight a12-hour After standards). (WHO median the from deviation standard >2 was age academic hospital in the state of Qatar. Parents of children younger than 18 years of age were offered an interview survey. interview an offered were age 18 of than years younger children of Qatar. Parents of state the in hospital academic analysis of the available literature. available the of analysis (>30U/L) and UA (>330 µmol/L) the sensitivity and specificity of GGT in predicting fatty liver was 26.9% and 94.1% respectively while for UA is is for UA while 94.1% and 26.9% was respectively liver fatty predicting GGTof in specificity and sensitivity the µmol/L) UA (>330 and (>30U/L) of 0.99 (sensitivity 77.9% and specificity 55.1%) for AST/ALT and 2.02 (sensitivity 73.2, specificity 58.5) for HOMA-IR predicted fatty liver. fatty predicted HOMA-IR for 58.5) 55.1%) specificity 73.2, AST/ALTfor 77.9% specificity and 2.02 (sensitivity and (sensitivity 0.99 of Lanka. Sri in children obese of cohort com considered high in a small country. Involving parents in road safety decision making can lead in the decline of morbidity and mortality due road road due mortality and morbidity of decline the in lead can making decision safety road in parents Involving country. asmall in high considered consistent application of diagnostic methods according to Graf, contributes to the objectivity, repeatability, feasibility and economically viability viability screening. DDH of economically and feasibility repeatability, objectivity, the to contributes Graf, to according methods diagnostic of application consistent is method ascreening as examination clinical DDH, of diagnosis early of problem the to paediatricians of sensitization the Despite child. was method Graf The abduction. hip limited and tests Ortolani and Barlow the included examination clinical The ultrasound. by and clinically danger. 1 1 1 specificity 57.4%) for UA,27.5U/L (sensitivity 70.5%,specificity 51.5%) for AST,21.5U/L (sensitivity 80.8% and specificity 61.8%) for specificity ratio and a ALT, 80.8% 51.5%)for AST,21.5U/L 57.4%)(sensitivity 70.5%,specificity for UA,27.5U/L specificity (sensitivity safety, and share our data with authorities to assist in implementing campaigns against speeding. against campaigns implementing in assist to authorities with data our share and safety, CHILDREN IN A TERTIARY CARECENTRE Presentation Oral Presentation Oral by provided training, Well-structured findings. negative false of proportion large the and sensitivity low its to due insufficient and subjective Presentation Oral University of Colombo,Sri Lanka; Lanka; Colombo,Sri of University recognized clinically. 9% of the population covered by the DDH screening were referred to a paediatric orthopaedist for further observation. observation. further for orthopaedist apaediatric to referred were screening DDH the by covered population the of 9% clinically. recognized SCREENING FORDEVELOPMENTAL DYSPLASIA OFTHEHIP (DDH): PAEDIATRICS CHALLENGES which meets the criteria to be included in screening programme. screening in included be to criteria the meets which used for the ultrasound examination. ultrasound the for used Conclusion: Conclusion: fatty liver and AST, ALT, AST/ALT ratio, insulin resistance assessed by homeostasis model (HOMA-IR),UA and GGT. With existing cut offs GGT GGT offs cut GGT. (HOMA-IR),UA and existing model With homeostasis by AST, and liver ALT, assessed fatty AST/ALT resistance insulin ratio, forms of DDH at the age of 4 to 6 weeks, and provide orthopaedic therapy that is rational, accessible and practical for the parents and their their and parents the for practical and accessible rational, is that therapy orthopaedic provide and 6weeks, 4to of age the at DDH of forms surgically. treated were children the of none and therapy, orthopaedic conservative underwent population the of 2.8% Results: a (GGT) in (UA) gamma-glutamyltransferase and acid uric serum with liver fatty of association the investigate to was objective Our Purpose: Our purpose was to delineate parental concept of road safety in the State of Qatar, integrate parental thoughts and ideas into public public into ideas and thoughts parental Qatar, integrate of State the in safety road of concept parental delineate to was purpose Our Purpose: the basis of our own twenty-years of experience in conducting non-selective, combined clinical and ultrasound DDH screening, and a critical acritical and screening, DDH ultrasound and clinical combined non-selective, conducting in experience of twenty-years own our of basis the on programme, screening DDH the for responsible be should paediatricians why arguments present to was study this of aim The Purpose: Results: Dinesha Maduri Vidanapathirana 38.5% and 83.8% respectively. A cut-off value of 18.5 U/L (sensitivity 76.9% and specificity 52.9%) for GGT,277µmol/L (sensitivity 70.5% and and 70.5% GGT,277µmol/L for 52.9%) (sensitivity specificity and 76.9% (sensitivity 18.5 of U/L value Acut-off respectively. 83.8% and 38.5% for index mass body whose children 5-15 obese year-old among conducted was study analytical Across-sectional Methods: and Materials A cross-sectional prospective study was conducted at Hamad Medical Corporation, the only tertiary care and and care tertiary only the Corporation, Medical Hamad at conducted was study prospective Across-sectional Methods: and Materials Mohamed Hendaus Mohamed Methods: INVOLVING PARENTS INROADSAFETY DECISIONMAKING:KEEPINGOURCHILDRENSAFE Barlow test, and 210 had limited hip abduction. 72% of the pathological hips (3 subluxation and 1 dislocation) shown by ultrasound were not not were ultrasound by shown 1dislocation) and (3 subluxation hips pathological the of 72% abduction. hip 210 limited and had test, Barlow licensed, professionally authorized educators, with the possibility of continual renewal of knowledge, is vital for optimal screening for DDH. The The DDH. for screening optimal for vital is knowledge, of renewal continual of possibility the with educators, authorized professionally licensed, Introduction: Introduction: Irena Bralić Irena 8 /OP4: 237 ID: Introduction: ID: 152 9 /OP4: ID: ID: 175ID: 10 /OP4: University of Split, School of Medicine, Croatia, Croatia; Croatia; Croatia, Medicine, of School Split, of University Department of Chemical Pathology, Lady Ridgeway Hospital, Sri Lanka; Lanka; Sri Hospital, Ridgeway Lady Pathology, Chemical of Department Hamad Medical Corporation, Qatar; Qatar; Corporation, Medical Hamad OP4: PRESENTATIONS: ORAL 4 SESSION We studied 146 obese children with a mean age (SD) 9.86 (2.1). Chi square test showed statistically significant associations between between associations significant (SD) (2.1). age statistically 9.86 amean showed with test square children Chi 146 obese We studied 89.4% of the infants had normal findings by ultrasound and 92.3% of the infants examined clinically. None had a positive Ortolani or or Ortolani positive a had None clinically. examined infants the of 92.3% and ultrasound by findings normal had infants 89.4% the of At their first regular check-up by a paediatrician at the age of 4 to 6 weeks, a total of 2720 infants with 5440 hips were examined examined were hips 5440 with infants 2720 of total a weeks, to 6 of 4 age the at paediatrician by a check-up regular first At their 20 9 t h 1 GGT and UA are associated with fatty liver and these biomarkers can be used to predict fatty liver disease. liver fatty predict to used be can biomarkers these and liver fatty with associated UA GGT are and Paediatricians responsible for non-selective combined clinical and ultrasound screening of the hips are able to discover all all discover to able are hips the of screening ultrasound and clinical combined non-selective for responsible Paediatricians

E , Katija Kragić , Katija Obesity among the young is an emerging health problem with many metabolic changes including liver derangement. liver including changes metabolic many with problem health emerging an is young the among Obesity Every year more than 630 people are severely injured due to motor vehicle accidents in the State of Qatar. This prevalence is is prevalence Qatar. This of State the in accidents vehicle motor to due injured severely are people 630 than more year Every Developmental dysplasia of the hip (DDH) is the most common deformation of the loco-motor system, caused by multiple factors, factors, multiple by caused system, loco-motor the of deformation common most the is (DDH) hip the of dysplasia Developmental D I T 1 I 4 O 7 The Polyclinic Orthopedics Vrdoljak, Zagreb, Croatia; [email protected] Croatia; Zagreb, Vrdoljak, Orthopedics Polyclinic The N 1,2,3 Topics: Topics: Topics: Reem Emad El-Deen Wassef El-Deen Emad , Reem General Pediatrics, Infant Development Infant Pediatrics, General General Pediatrics, Obesity & Physical Activity &Physical Obesity Pediatrics, General General Pediatrics General 2 , Ozren Vrdoljak , Ozren 3 Department of Paediatrics, Faculty of Medicine, University of Colombo,Sri Lanka; maduri129@yahoo. Lanka; Colombo,Sri of University Medicine, of Faculty Paediatrics, of Department 1 , Eresha Jasinge , Eresha CONFERENCE PROGRAMME ABSTRACTS 2 Weill Medicine; Cornell 3 , Javor Vrdoljak , Javor 1 , Dulani Samaranayake 1 , Marwa Mansour , Marwa 2 Pediatrics Clinic, University Hospital Centre Split, Croatia; Croatia; Split, Centre Hospital University Clinic, Pediatrics 3 Sidra Medical & Research Center; [email protected] Center; &Research Medical Sidra 4

2 Department of Community Medicine, Faculty of Medicine, Medicine, of Faculty Medicine, Community of Department 1 , Tasneem Abdel-Karim , Tasneem 2 , Pujitha Wickramasinghe , Pujitha ORAL PRESENTATIONSORAL 1 , Ahmed Alhammadi , Ahmed 3 3 Children’s Hospital Hospital Children’s 1,2,3 73

Abstracts 74 2 3 ORAL PRESENTATIONS , Vânia Martins 2 Department of Pediatrics, Hospital Beatriz Ângelo, Loures, , Anabela Ferrão 2 2

Centro Hospitalar de Trás-os-Montes e Alto Douro, Portugal; , Cristina Cândido 2 2 , Sofia Costa Lima 2 , Inês Torrado 2 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE , Marta Contreiras 2 Endocrinology & Growth, Autoimmunes General Pediatrics , Sara Peixoto 1 Topics: Topics: , Sofia Moeda N 1 7 O I 1 T I D Thrombocytosis is common in children and frequently reactive to infections. Extreme thrombocytosis (platelet count>1,000,000/ Type 1 diabetes is an organ-specific Type (T1D) autoimmune disease caused by autoimmune response against pancreatic β cells. E

We found We autoimmune conditions associated in around one patients, third of T1D which overlaps comparing with other studies. A large proportion of residents in the State of Qatar perceive that children are not safe while commuting in roads. Social media, Few cases of extreme thrombocytosis have been reported in infants and to our knowledge none with such high platelet counts. h t 9 20 Unit of Pediatric Hematology, Department of Pediatrics, Hospital Santa Maria Lisbon, (CHLN), Portugal; joana.a.oliveira@ 3 300 questionnaires were completed (response Approximately rate =100%). 80% of parents were between 20 and 40 years of age. During this period, patients 102 were followed up. Range of ages was between months 18 years, and 18 mean of 9 years and similar OP4: ORAL PRESENTATIONS: SESSION 4 ORAL PRESENTATIONS: OP4: Centro Hospitalar de S.João, Porto - Portugal, Portugal; Department of Pediatrics, Hospital Santa Maria Lisbon, (CHLN), Portugal; be the most consensual prophylactic option. Cytoreductive treatment (drugs or platelet apheresis) may be considered in high-risk cases, but ID: 278 / OP4: 12 hotmail.com Introduction: hyperthyroidism and four with hypothyroidism) through the necessity of pharmacotherapy; four had celiac disease, confirmed by endoscopy Introduction: ID: 265 / OP4: 11 intravenous ampicillin and cefotaxime (for presumed bacteremia) and oral aspirin 5 mg/kg/day. She remained clinically well and apyretic internal affairs, endowment and guidance to assist to launch campaigns using specific road safety messages. Besides, around 26% had positive antibodies diagnosis, at T1D which claim the attention to tracking autoimmune related conditions at Materials and Methods: Retrospective study of the clinical records and analytical examinations of the children and adolescents with T1D Results: Results: Purpose: Identify the association between autoimmune conditions diagnosed and T1D in children. to rise to a maximum until day 14 of 6,502,000/mm3, with subsequent decrease. Bone marrow aspirate showed no abnormal findings and their own possible complications must be taken into account. Although extremely high platelet counts cause great concern in pediatric care, it is followed in our Pediatric Diabetes Consultation between and September 2017. August 2012 31, 1, fluid(CSF) analysis and chestX-Ray were normal.Peripheral blood smear showed no blasts. The infantwas admitted and started on WBCfrom count day 1. increased and up to 52,100/mm3 CRP up to 18.54 mg/dL until day 2 of antibiotics after (ABs), which they gradually 85% of parents agreed and strongly agreed that the car speed limit should be pre-set by local authorities, while 70% believed that it would be Portugal; Parents were also asked of the best place to receive road safety information. Almost 50% preferred to receive itthrough social media, while EXTREME THROMBOCYTOSIS IN AN INFANT: MUCH ADO ABOUT NOTHING? ADO MUCH AN INFANT: IN EXTREME THROMBOCYTOSIS positive antibodies during the firstyear diagnosis. Other conditions associated were: pulmonary hemosiderosis, vitiligo, IgA deficit,uveitis [email protected] Conclusion: while riding with them in the Moreover, only car. ofparents 47% always used car seats, seatbelts and proper restraints. This is in-spite that wise to use electronic chips in car for keys monitoring speed. It’s worth mentioning that female parents, were more open to this idea (p=0.008). Conclusion: with presumable bacterial infection, who had no complications. Case Report: A healthy 7 week-old girl was admitted to the Emergency Department for fever (38.5ºC) and mild nasal congestion. No other Contrarily to what has been described in adults, extreme thrombocytosis in infants, when reactive to infection, doesn’t seem to be associated Conclusion: with increased risk of complications. The need for treatment is controversial and usually decided on a case-by-case basis. Aspirin seems to nearly 82% of parents felt that these restraints protect children in case of an accident. Whenasked if it is safe to exceed the speed limit if mm3) is rare and its clinical implications in Pediatrics not well understood. describe We a case of extreme reactive thrombocytosis in an infant normal cardiorespiratory auscultation, and no other remarkable physical findings. Lab works showed hemoglobin9.6 g/dL, white blood cell Oral Presentation reasonable to wait for spontaneous resolution in the asymptomatic infant with reactive thrombocytosis. Oral Presentation symptoms or contact with ill people were reported. Physical examination showed a well-appearing infant, no respiratory distress, no hypoxemia, 1 1 diagnosis. Despite the positivity of antibodies, it is important to be aware for the possibility of other less common autoimmune related conditions driving 60% safely, of parents believed that it was not a good idea. The concept of controlling speed limit was investigated, and it showed that determination. From this tracking we found positive autoantibodies thyroid antibodies antibodies in 31%: (n=16), for celiac and disease (n=10) decreased and normalized ABs by were day 10. maintained days, for with 10 negative blood, urine and CSF cultures. Platelet counts continued discharged on day 20. Complete remission was achieved 4 months after the diagnosis. gender distribution (53% females and males). In 98% 47% was performed, at least, one tracking of other autoimmune disease with antibody (WBC) count 45,600/mm3, 66% neutrophils, platelet count 2,580,000/mm3 and C-reactive protein 8.38 (CRP) mg/dL. Urinalysis, cerebrospinal associated. The screening of comorbidities is fundamental to make an earlier diagnosis and prevent complications. antinuclear antibodies (n=5). Antibodies positivation occurred, in mean, 3.6 years diagnosis. after T1D about However, 26% of patients had and positive Anti-Saccharomyces cerevisiae antibodies. Despite the positivity of antibodies, five had thyroid clinical disease(one patient with and with gluten free diet. From all patients, 62 maintain follow up in our consultation. Vanessa Oliveira Gorito a space where most of our community inhabits, seemsto be the best setting to target our people. will We share our data with the ministries of Almost 40% of participating families reside outside the capital city of Doha. Interestingly only 1 in 2 parents thought their children were safe Joana A. Oliveira 44.3% opted for local television. JAK2 V617F mutationJAK2 was V617F absent. The infant remained clinically stable, with no evidence of thrombotic or haemorrhagic events, and was TYPE 1 DIABETES AND AUTOIMMUNE RELATED CONDITIONS – A RESEARCH STUDY IN A PORTUGUESE HOSPITAL A IN RESEARCH STUDY A CONDITIONS – RELATED AUTOIMMUNE AND TYPE 1 DIABETES The T1D-inducing autoimmune process canalso affect other organs, resulting in the development of additional autoimmune diseases.

Abstracts Jichi Medical University Saitama Medical Center, Japan; [email protected] Center, Japan; Medical Saitama University Medical Jichi

Vila Nova de Gaia Espinho, Portugal; [email protected] Portugal; Espinho, Gaia de Nova Vila and acceptance within families. Except for DFV, other CT used may be an option if treatment is initiated; CPL can be considered in treatment treatment in considered be CPL can initiated; is treatment if option an be may CTused DFV, for other Except families. within acceptance and other with 90.9% vs (20% resolution of rate alower with associated DFV groups. surveillance/treatment the between differences no and establish a new method to estimate cerebral circulation without the influence of ductal shunt in newborn infants. newborn in shunt ductal of influence the without circulation cerebral estimate to method anew establish (CAD, LPAD) were measured in ACA and LPA, respectively, and resistance index (RI), pulsatile index (PI) and LPAD/LPAS (PI) and index calculated. were (RI), pulsatile index resistance and LPA, ACA(CAD, in respectively, and LPAD) measured were Presentations conservative surveillance approach. surveillance conservative CT, (n=2). 47.1% Regarding propionate, 11.7% (n=1) (n=1), furoate, surveillance or cryotherapy pimecrolimus fluticasone mometasone used isconditions controversial. 1 QUANTITATIVE EVALUATION OFPDA FLOWS AFFECTING CEREBRAL BLOODFLOWINNEWBORNINFANT CHILDHOOD GRANULOMA ANNULARE. A 16-YEARCLINICAL PERSPECTIVEFROM A PEDIATRIC HOSPITAL Presentation Oral recorded in a sagittal view by pulsed Doppler with supported color flow imaging positioning a transducer on the anterior fontanel. The flow flow The fontanel. anterior the on transducer a positioning imaging flow color supported with Doppler pulsed by view asagittal in recorded Presentation Oral 77.3%in and investigated (TD)were disease (DM1) thyroid groups. and Type 1diabetes treatment/surveillance between differences significant Biopsy 4.5%. in 9.1%, in lesions nodules both and subcutaneous violaceous (LGA) 81.5%, GA in isolated localized of features typical revealed System. Recordings were obtained while the infants were asleep or resting quietly with stable heart rates. The flow velocity curve of ACA was of ACA was curve velocity flow The rates. heart stable with quietly resting or asleep were infants the while obtained were Recordings System. mixed LGA/SGA in 4.5%. Lesions developed after sun exposure in 22.7% and minor trauma in 4.5%; 13.6% of the children were obese. obese. were 4.5%; children in 13.6% the of trauma minor and 22.7% in exposure sun after developed Lesions 4.5%. in LGA/SGA mixed malformations or severe respiratory distress whose blood flow velocity curves of anterior cerebral artery (ACA) and left pulmonary artery (LPA) artery pulmonary left (ACA) and artery cerebral anterior of curves velocity flow blood whose distress respiratory severe or malformations Surveillance yielded positive results, emphasizing its benign and often self-limited course and supporting it as a valid option for most cases cases most for option avalid as it supporting and course self-limited often and benign its emphasizing results, positive yielded Surveillance dyslipidemia. or uveitis neoplasia, Conclusion: was performed only in n=2, yielding a diagnostic result in 1. Final classification was LGA in 86.4%, subcutaneous GA in (SGA) 9.1%, and subcutaneous 86.4%, in LGA was 1. classification in Final result adiagnostic yielding n=2, in only performed was were recorded by pulsed Doppler ultrasonography within 6 hours after birth. The instrument used was a Philips Model iE33 Color Flow Imaging Imaging Flow Color iE33 Model aPhilips was used instrument The birth. after 6hours within ultrasonography Doppler pulsed by recorded were were the first-line agents in all. If recurrence/no resolution (n=7), alternative options were contrast-pulsed-laser (CPL; n=4), other CT (n=2), n=4),other (CPL; contrast-pulsed-laser were options (n=7),alternative resolution recurrence/no If all. in agents first-line the were Conclusion: CBF and ductal shunt is unclear. is shunt ductal and CBF velocity curve of LPA was recorded in a parasternal short axis view. The systolic maximal velocities (ACAS, LPAS) and end-diastolic velocities velocities (ACAS, LPAS) end-diastolic and velocities maximal systolic The view. axis short aparasternal in LPA of recorded was curve velocity prognosis of a newborn with asphyxia. It is known that ductal shunt influences cerebral blood flow, however, the quantitative relation between between relation flow,quantitative however, the blood cerebral influences shunt ductal that known is It asphyxia. with anewborn of prognosis DERMATOLOGY DEPARTMENT. Familial dermatologic history was unremarkable. Treatment was initiated in 77.3% of the cases. Medium/high-potency topical corticoids (TC) (TC) corticoids topical Medium/high-potency 77.3% in cases. the of initiated Treatment was unremarkable. was history dermatologic Familial 29.4% diflucortolone valerate (DFV) and 5.8% clobetasol propionate. Ninety-one percent resolved, within a median time of 19.8 months, of months, time 19.8 median a within resolved, percent Ninety-one propionate. clobetasol 5.8% and (DFV) valerate 29.4% diflucortolone failures. None of the reported medical conditions associated with GA developed at follow-up, possible obviating investigations towards a more amore towards investigations obviating possible follow-up, at developed GA with associated conditions medical reported the of None failures. Results: treatments; p=0,013). All other TC and CPL yield satisfactory, though not statistically significant results. Fifteen percent recurred, with no no with recurred, percent Fifteen results. significant statistically not though satisfactory, CPL yield TC and other p=0,013). All treatments; Results: Department. Dermatology Hospital Pediatric aPortuguese in diagnosed CGA of features clinical the To describe Purpose: In this research, we quantitatively estimated the influence of ductal shunt to cerebral blood flows blood cerebral to shunt ductal of influence the estimated quantitatively we research, this In Purpose: Ko Ichihashi Maria Isabel Bento Ayres Pereira Leite Pereira Ayres Bento Isabel Maria 31.8%, respectively; medical records were reviewed until the present age (median follow-up 7.5 years). No case was diagnosed with DM1, with TD, 7.5 diagnosed was case years). follow-up No (median age present the until reviewed were records medical 31.8%, respectively; 16 used. v.20 SPSS was years; last the in diagnosed CGA of study observational Retrospective Methods: and Materials We examined retrospectively the medical records of 123 newborn infants without asphyxia, major cardiac cardiac major asphyxia, without infants 123 of newborn records medical the retrospectively We examined Methods: and Materials 0.80±0.12, 1.73±0.41 and 0.28±0.01, respectively. There is a significant correlation between RI and LPAD/S and RI (P<0.001, between r=0.58). correlation asignificant is There 0.80±0.12, 1.73±0.41 respectively. 0.28±0.01, and in 95.5% and localized to the feet (54.5%), ankles (27.3%), tights (18.2%), legs (18.2%) and hands (18.2%); 68.2% had >1 lesion. Examination (27.3%), (54.5%), feet the to ankles (18.2%), Examination (18.2%); >1 (18.2%) had tights hands localized lesion. legs and and 68.2% 95.5% in / OP5: 1 /OP5: 230 ID: Introduction: / OP5: 2 210 /OP5: ID: Introduction: █ Pediatric Department, Centro Hospitalar Vila Nova de Gaia Espinho, Portugal; Portugal; Espinho, Gaia de Nova Vila Hospitalar Centro Department, Pediatric OP5: PRESENTATIONS: ORAL 5 SESSION █ Time: OP5: PRESENTATIONS: ORAL 5 SESSION Birth weight and gestational age of the newborns are 2470±645 grams and 36.4±2.6 weeks, respectively. RI, PI, and LPAD/S are LPAD/S PI, RI, and are respectively. weeks, 36.4±2.6 and grams 2470±645 are newborns the of age gestational and weight Birth 22 cases were identified, with a male:female ratio of 1:2.1 and median age at appearance of 5 years-old. Lesions were asymptomatic asymptomatic were Lesions of 5 years-old. appearance of at age ratio 1:2.1median male:female and a with identified, were cases 22 20 9 Friday, 08/Dec/2017:5:00pm-6:30pm•Location:Turin Hall t h In this study, we showed the quantitative relation between CBF and ductal shunt. From these results, we might be able to to able be might we results, these From shunt. ductal and CBF between relation quantitative the showed we study, this In To the authors Knowledge, this is the first study of CGA from 1-18 years old. Clinical features were in accordance to literature. literature. to accordance in were features from 1-18 Clinical CGA of old. study years first the is this Knowledge, To authors the

E It is important to evaluate cerebral blood flow (CBF) by ultrasonography to diagnose asphyxia or to predict developmental developmental predict to or asphyxia diagnose to ultrasonography by (CBF) flow blood cerebral evaluate to important is It Childhood granuloma annulare (CGA) is a common inflammatory dermatosis of unknown etiology. Association with other other with Association etiology. unknown of dermatosis inflammatory (CGA) acommon is annulare granuloma Childhood D I T 1 I O 7 N Topics: Topics: General Pediatrics, Dermatology Pediatrics, General Preterm Infant, NICU Infant, Preterm CONFERENCE PROGRAMME ABSTRACTS 1 , Cátia Leitão , Cátia 1 , Andreia Ribeiro , Andreia

1 , Ana Luísa Leite Luísa , Ana 2 Pediatric Dermatology Department, Centro Hospitalar Hospitalar Centro Department, Dermatology Pediatric ORAL PRESENTATIONSORAL 1 , Eduarda Osório , Eduarda 2 75

Abstracts 76 ORAL PRESENTATIONS

ABSTRACTS CONFERENCE PROGRAMME CONFERENCE Preterm Infant, NICU Preterm Infant Topics: Topics: N 7 O I 1 , Pankaj Manish Yadav, Mittal, Rohit Arora T I D Quality control, and adherence to written NICU specific guidelines, are known to impact outcomes in preterm neonates. As part Research on theoutcomes of preterm birth has focused primarily on negative consequences. Little attention has been paid to E

Implementing quality initiatives in the form of standardized management guidelines for preterm VLBW neonates was associated A substantial minority of school-age children EP demonstrated age-appropriate achievement, behavior, and daily living skills. h t 9 20 There was significant decrease in culture positive sepsis in the intervention group compared to control groupCI:0.006- (2.97%) (3, Only 36 children had positive (28%) outcomes, but rates ofthese outcomes varied significantly13% forfrom children at both OP5: ORAL PRESENTATIONS: SESSION 5 ORAL PRESENTATIONS: OP5: biological and demographic risk to 53% for those without either risk factor (p=.002). Each risk factor contributed to outcome independentlyof ID: / OP5: 146 4 Introduction: Introduction: ID: 115 / OP5: 3 ID: 115 hemorrhage, gestational diabetes mellitus, chorioamnionitis, birth weight and sex were well matched in both the groups. 0.08 vs 11 (19.64%) CI:0.10 - 0.32 ; p:0.0004). Similarly, the number CI:0.10 of days on mechanical (19.64%) 0.08 vs ventilation 11 was significantly reduced(mean number if the child met DSM-IV criteria for a psychiatric disorder. Children without a psychiatric disorder who were free of deficits in achievement, intervention group There p:0.049). (mean 4.03 was (CI:2.62-5.44) no significant vs 2.2 days (CI:1.01-3.38), difference in the survival(94.64% language, and daily living skills were classified as having a positive outcome; children with a psychiatric disorder or deficit in one of these areas Methods and Materials: Four quality initiatives were introduced and written guidelines and checklists were prepared for each of them. Training Materials and Methods: The sample comprised children 130 born from 2001-2003 at a single neonatal center with gestational age <28 Sunaina Arora Sunaina H. Gerry Taylor Nationwide Children’s Hospital Research Institute, UnitedStates of America; [email protected] to December (Intervention 2016 Group) and compared with retrospective matched controls from the previous – June year 2015) (July 2014 Results: the prevalence of positive outcomes and factors that may account for the age-appropriate levels of functioning of some preterm children. Purpose: The aims of this study were to examine the rate of positive outcomes in a sample of extremely preterm children (EP) and compare them to children EP with more negative outcomes on measures of biological and social risk, family characteristics, and child social and Results: the other (p<.05). Other factors associated with positive outcomes included more stimulating home environments, caregiver endorsements of NEONATAL OUTCOMES IN VERY LOW BIRTH WEIGHT INFANTS IN TERTIARY CARE NICU IN NORTH INDIA. IN TERTIARY INFANTS LOW BIRTH WEIGHT OUTCOMES IN VERY NEONATAL RESILIENCE IN CHILDREN BORN EXTREMELY PRETERM BORN EXTREMELY RESILIENCE IN CHILDREN parenting satisfaction and promotion of child autonomy, and higher child social competence and cognitive abilities p’s<.05). (all vs 96.03% or mortality 0.738) p: amongst (5.35% the vs 3.96% two 0.74) groups. p: All other morbidities such as bronchopulmonary dysplasia, variables like maternal age, gestational age, antenatal steroids, maternal complications like pregnancy induced hypertension, antepartum Conclusion: was provided to each of the doctors and nursing staff on implementation of these guidelines. The quality initiatives identified and Adoptingimplemented a) were: Humidified and Heated High Flow Nasal Cannula(HHHFNC) as primary mode ventilation.of b) Using onlyexpressed breast weeks and/or birth weight <1000 g. The majority of the sample was (72%) at high biological risk as defined by a major neonatal complications were classified as having a negative outcome. The two subgroups were compared on measures of biological and demographic risk, the home Conclusion: with significant reduction in culture proven sepsis and mechanicalventilation days without affecting mortality or other co-morbidities. milk / donor milk for feed and absolutely no formula milk feed. Maintain c) strict asepsis with primary focus on hand washing and following minimal handling, prone positioning, clustering of care and dim lights/low noise environment. Data was collected prospectively from July 2015 necrotising enterocolitis, intraventricular hemorrhage, and retinopathy of prematurity were statistically insignificant in both groups. Other management guidelines as part of quality initiative program in a tertiary care NICU in North India. Oral Presentation Objective: study and To compare the morbidity and mortality outcomes of VLBW neonates before and after introduction of standardized sociodemographic risk, parenting, and the home environment. A formal psychiatric interview was also conducted with parents to determine Oral Presentation of environmental advantage to positive outcomes and provide impetus for further research on neural plasticity following preterm birth. of quality initiative, we introduced a standardized written guideline-based approach towards the management of VLBW neonates. cognitive competence. cognitive or neurodevelopmental impairment in early childhood. of academic Tests and cognitive skills were administered to the children at mean of days in intervention vs control group (1.19,CI: 0.27-2.1 vs 3.36of days CI:2.27-4.44, in intervention 0.27-2.1 p:0.002) while number vs control of days on HHHFNC was group increased (1.19,CI: in the (Control Chi Group). square test was used for data analysis. environment and parenting, and child social and cognitive abilities. age 8.0 Their years (SD=.4). teachers completed ratings of social competence; parents provided information on children’s daily living skills, Although these “resilient” children were at lower biological risk than those with learning or behavior problems, the findings confirm the contribution Apollo cradle hospital, India; [email protected] TO ASSESS THE IMPACT OF QUALITY INITIATIVE PROGRAM USING STANDARDISED MANAGEMENT GUIDELINES ON PROGRAM USING STANDARDISED INITIATIVE OF QUALITY ASSESS THE IMPACT TO “Bundle Care Approach” forCentral lines and PICC lines and d) Development and supportive care through a checklist based approach on

Abstracts AUTISM SPECTRUMDISORDERSCREENINGIN A PRIMARY CAREFACILITY Aim: Fig 1 Fig test) Wilcoxon (p<0.0001 iNO of administration as sex, parental age, family history of ASD and primary care attendance were also obtained. also were attendance care primary and ASD of history family age, parental sex, as (63%) were eligible for 2-year Neurodevelopmental assessment and 5/10 (50%) showed age appropriate development. appropriate age 5/10 (50%) and showed assessment Neurodevelopmental 2-year for (63%) eligible were 9/11 with (82%) non-survivors. and survivors between p= 0.6404) (Mann-Whitney age gestational in difference 0.0152), significant no was (p= there but effective therapy to improve respiratory failure. respiratory improve to therapy effective databases as well as developmental assessment reports and clinic letters. clinic and reports assessment developmental as well as databases of external hydrocephaly and, therefore, no follow-up interview was done. The three follow-up interviews were negative for autism spectrum spectrum autism for negative were interviews follow-up three The done. was interview follow-up no therefore, and, hydrocephaly external of disorder. Portuguese the for is validated M-CHAT-R/F rate: 72%) The (response children of 160 sample afinal to leading attempts, three after contacted care facility using the M-CHAT-R/F. the using facility care with revised toddlers in autism for checklist modified The old. 18 24 months and between children all of screening recommends Paediatrics of descriptive statistic methods using SPSS version 20.0. All 220 children between 18 and 24 months from February to June of 2017 enrolled 2017 of June to enrolled February from 18 24 months and between children 220 All 20.0. version SPSS using methods statistic descriptive 1 OUTCOME OFPRETERMINFANTS WHORECEIVEDINHALEDNITRICOXIDE(INO)TO TREAT HYPOXIC RESPIRATORY received rescue iNO for hypoxic respiratory failure. respiratory hypoxic for iNO rescue received non-survivors in the first two weeks of life. In Survival group, discharge cranial ultrasound showed normal results 10/16 (63%), hydrocephalus 2/16(13%), 10/16results (63%), normal hydrocephalus showed ultrasound cranial discharge group, Survival In life. of weeks two first the in non-survivors Presentation Oral Presentation Oral multifactorial; however survival was 67%, only 37% of them needed home O2 and 50% had normal development at 2years. at development normal had 50% and O2 home needed them of 37% only 67%, was survival however multifactorial; ≥2wks. Mean age at starting iNO was 19 hours (1.7- 240 hrs). There was significant difference in Oxygenation index (OI) before and one hour after after hour one and before (OI) index Oxygenation in difference (1.7- 19 was hours iNO significant was hrs). 240 There starting at age Mean ≥2wks. use, but in some circumstances, when pulmonary hypertension is associated with severe respiratory failure, iNO has been demonstrated as an an as demonstrated been has iNO failure, respiratory severe with associated is hypertension pulmonary when circumstances, some in but use, Conclusion: Catarina Ferraz de Liz de Ferraz Catarina usually present by the second year of life with a general developmental delay, however most children are not diagnosed until age four or older. older. or four age until diagnosed not are children most delay, however developmental ageneral with life of year second the by present usually population. The authors applied the survey by telephone interview to parents/legal guardians. Demographic characteristics of the sample such such sample the of characteristics Demographic guardians. parents/legal to interview telephone by survey the applied authors The population. PVL 3/6(19%) and hydrocephalus + PVL 1/6(6%). 10/16 (63%) had chronic lung disease, however only 6/16 (37%) discharged on home oxygen. 10/16 oxygen. home on 6/16 (37%) only however discharged 1/6(6%). +PVL disease, lung 10/16 3/6(19%)PVL hydrocephalus (63%) chronic had and of 2/8 versus IVH III-IV grade had test). 3/16 survivors exact of Fisher’s (p=0.2108 7/13 versus (54%) PROM<2weeks with survived ≥2weeks PROM FAILURE PROM ≥2wks showed dramatic response to iNO and had higher rates of survival. The outcome of this cohort of very sick preterm infants is is infants preterm sick very of cohort this of outcome The survival. of rates higher had and iNO to response dramatic showed ≥2wks PROM Early detection of this condition is essential to establish effective behavioral intervention allowing a better prognosis. The American Academy Academy American The prognosis. abetter allowing intervention behavioral effective establish to essential is condition this of detection Early Results: follow-up (M-CHAT-R/F) is a valid screening tool that detects ASD at a higher rate when compared to the M-CHAT previously used. previously M-CHAT the to compared when rate ahigher at ASD detects that tool screening avalid is (M-CHAT-R/F) follow-up Results: The aim of this study was to characterize the prevalence of autism spectrum disorder in children from 18 to 24 months in a primary aprimary in 18 24 to from months children in disorder spectrum autism of prevalence the characterize to was study this of aim The Purpose: Fig 1: Fig [email protected] Kingdom; United Hospital, University Dunstable and Luton Discussion: [email protected] Lagoa; Familiar Saúde de Unidade Matosinhos- de Saúde de Local A retrospective review was carried out of all preterm infants < 35 weeks admitted to our tertiary NICU who required required who NICU tertiary our to admitted weeks <35 infants preterm all of out carried was review Aretrospective Methods: and Materials Mona Noureldein Mona 3,2). Of all the screenings made 4 scored positive (2,5%). One was already accompanied due to general developmental delay in the context context the in delay developmental general to due accompanied (2,5%). already was One positive 4scored made screenings the all 3,2). Of This was a cross-sectional study. Demographic characteristics of the sample and results were analysed through through analysed were results and sample the of characteristics Demographic study. across-sectional was This Methods: and Material iNO for hypoxic respiratory failure between Jan 2012 to Dec 2016. Data was collected from local, national electronic and other relevant relevant other and electronic national local, from 2012 collected 2016. was Jan Dec Data to between failure respiratory hypoxic for iNO / OP5: 6 /OP5: 269 ID: iNO of indication approved the in included not are infants newborn Premature newborns. term near or term in failure respiratory hypoxaemic Introduction: 5 /OP5: 227 ID: in the family health Unit with a total of 17000 patients were invited to take part in the study. Nine chose not to participate and 50 couldn’t be be couldn’t 50 and participate to not chose Nine study. the in part take to invited were 17000 patients of atotal with Unit health family the in Introduction: Centro Hospitalar Tâmega e Sousa, Portugal; Portugal; eSousa, Tâmega Hospitalar Centro OP5: PRESENTATIONS: ORAL 5 SESSION To evaluate mortality, morbidity and Neurodevelopmental outcome at 2 years CGA of all preterm infants < 35 weeks gestation who who gestation weeks <35 infants preterm all of CGA 2years at outcome Neurodevelopmental and morbidity To mortality, evaluate OI before and 1 hour after iNO after 1hour and before OI We included 24 babies with gestation of 24+1 to 34+2weeks (mean 27+6w) and birth weight 540- 2980g (mean 1321g). (mean 2980g 11/24 540- weight PROM had 27+6w) birth (mean and 24+1 of 34+2weeks to gestation with 24 babies We included Fifty four percent of the sample (n=160) were female with a mean age of 23 months at the time of the contact (standard deviation deviation (standard contact the of time the at months 23 of age amean (n=160) with female were sample the of percent four Fifty 20 9 t h Our work represents an exploratory study, as there are no similar studies published in our country. our in published studies similar no are there as study, exploratory an represents work Our Reversal of pulmonary hypertension and hypoxia was rapid and effective in our cohort of preterm infants. Patients with with Patients infants. preterm of cohort our in effective and rapid was hypoxia and hypertension pulmonary of Reversal

E Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator that has been demonstrated its efficacy when used to treat treat to used when efficacy its demonstrated been has that vasodilator pulmonary aselective is (iNO) oxide nitric Inhaled Autism spectrum disorder (ASD) is a neurodevelopmental dysfunction that affects 1 in 88 children. Clinical manifestations are are manifestations Clinical children. 88 1in affects that dysfunction (ASD) aneurodevelopmental is disorder spectrum Autism D I T 1 I O 7 N , Hoi Shing, Srinivas Nallagonda, Sateesh Somisetty Sateesh Nallagonda, Srinivas Shing, , Hoi Topics: Topics: 1 , Filipa Martins Guedes Martins , Filipa General Pediatrics, Infant Development Infant Pediatrics, General Infant Preterm CONFERENCE PROGRAMME ABSTRACTS 2 . 16/24 (67%) survived and 8/24 (33%) died, birth weight was significantly higher in survived group group survived in higher significantly was weight birth (33%) 8/24 died, and . 16/24 (67%) survived Unidade Local de Saúde de Matosinhos- Unidade de Saúde Familiar Caravela; Caravela; Familiar Saúde de Unidade Matosinhos- de Saúde de Local Unidade 2 , Raquel Braga , Raquel 3

ORAL PRESENTATIONSORAL 3 Unidade 77

Abstracts 1,2 78 , Susana 1 , HerciliaGuimarães , , , Ana Lopes 1 1 Faculdade de Medicina da , Gorett Silva 2 1 , , Armanda Passas 1 ORAL PRESENTATIONS Hospital Center of Tâmega e Sousa, Penafiel,Portugal; , Cátia Leitão , Jorge Santos Silva 2 1 1

, Marta Rosário , Isabel Pereira Isabel , 1 2 , Teresa Pena 1 , Cláudia Teles Silva 1 ABSTRACTS CONFERENCE PROGRAMME CONFERENCE General Pediatrics, NICU Infant Development 1 Topics: Topics: N , , Maria Rangel Adriana , Mayara Nogueira Mayara , 1 7 O 1 I 1 T I D Neonatal jaundice is frequently diagnosed during the first days of life of newborns in perinatal care. Recent data has implicated Comparative genomic hybridization (CGH)-microarray is genetic a tool that analyzes the whole genome for detection of sub E

The identification of the clinical risk factors associated with neonatal jaundice and ultimately to the use of phototherapy help The results of our study are in agreement to those previously described, namely the prevalence of pathogenic variants and Despite our results the M-CHAT-R/F is a useful test in primary care, easy to apply and enables an early detection as of ASD, h t 9 20 302 newborns were included, of which 50.7% were male. The mean for gestational age was 38,94 eutocic weeks weeks), 1,36 (SD CGH-microarray was performed in 335 patients, 68.4% males, with years. a mean age Seventy of 8.1±4.0 seven percent had , Helena Santos 1 OP5: ORAL PRESENTATIONS: SESSION 5 ORAL PRESENTATIONS: OP5: Hospital Center of Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal; Serviço de Neonatologia, Hospital Pediátrico Integrado, Centro Hospitalar de São João, Portugal; between pathogenic microarray and female gender (p=0.006) and the presence of dysmorphic features (p<0.001). karyotype. Etiological diagnosis of ND brings benefits to clinical practice such as prognostic information and more adequate genetic ID: 185 / OP5: 8 its association with dysmorphic features. The use of this genetic technique allowed a higher etiological diagnostic yield than high-resolution ID: / OP5: 182 7 Introduction: Introduction: Materials and Methods: In this cross-sectional study, all newborns born between November and February 2016 in Maternity 2017 /Perinatal Microarray abnormalities were identified18.8%(n=63) in of patients(54.0% microduplication; microdeletion;39.7% 6.3% with 44.4% both); Materials and Methods: Retrospective observational and analytical study of paediatric patients with neurodevelopmental disorders in which Purpose: It seems important to characterize the major clinical risk factors for developing jaundice to be more alert in those cases and to Results: the clinical practice. In our study, the characteristics associated with this therapy were according to the literature. More studies are needed to Results: Purpose: describe To the experience of a Portuguese paediatric neuroscience unit with CGH-microarray technique for etiological study of Pereira Dysmorphic features were similar to phenotypes already described in their pathogenic variants Sixteen in 59.4%. of parents percent of (n=10) number of participants enrolled. NEONATAL JAUNDICE AND ITS MAIN RISK FACTORS – A CROSS-SECTIONAL STUDY CROSS-SECTIONAL A – AND ITS MAIN RISK FACTORS JAUNDICE NEONATAL Patients were divided in two groups according to CGH-microarray result (pathogenic vs not-pathogenic), and an association was found present, Rh incompatibility had was caput the most 14 succedaneum. common (10%). Neonatal jaundice was detected in 205 (67.9%) phototherapy was higher in males (p=0,03), in vacuum-assisted delivery (p=0,03) and in the presence of caput succedaneum (p=0,02). phototherapy, hour of life beginning phototherapy, serial bilirubin levels and hours of phototherapy were recorded. Newborns with intensive care phenotype). As part of an etiological performed study, 48.1% previous karyotype cerebral testing, MRI 48.1% (normal and in 73.5%) 45.3% Conclusion: Conclusion: CGH-microarray was used, during a three year period (2014-2016). Conclusion: use of this specific therapy, a permanent monitoring is needed. newborns with 78 needing phototherapy. Mean duration of phototherapy was The hours 36.7 incidence 20.4). (SD of newborns needing management were excluded. Statistical analysis was made with which SPSS 24, included descriptive analysis and application of T-student test metabolic study (normal CGH-microarray in 85.5%). allowed etiological of children with diagnosis (19/160) previous in normal 11.9% karyotype. neonatal jaundice and its mainstay treatment – phototherapy - with several diseases like asthma, autism and even cancer. Although the microscopic gains or losses of genetic material. Clinicians have increasingly used it as a first lineevaluation tool of children with multiple Spectrum Disorder (ASD). neurodevelopmental disorders and (ND) to determine predictors of pathogenic results. Oral Presentation IDD, 28.1% dysmorphic attention-deficit/hyperactivity 28.1% IDD, features, 20.6% 16.1% ASD, disorder7.5% had a familial(ADHD) and history of IDD. Oral Presentation Universidade do Porto, Porto, Portugal; [email protected] standardized use of phototherapy according with the American Academy of Pediatrics guidelines published in 2004 allowed the responsible When comparing to studies published in other countries our positive screening rate was lowerwhich could be justifiedby a low CLINICAL IMPACT OF GENOMIC MICROARRAY IN NEURODEVELOPMENTAL DISORDERS: 3-YEARS EXPERIENCE. DISORDERS: IN NEURODEVELOPMENTAL OF GENOMIC MICROARRAY IMPACT CLINICAL 1 1 delivery, delivery trauma, ABO/Rh incompatibility and feeding type. If neonatal jaundice was diagnosed, the bilirubin level at that time, use of delivery corresponded of deliveries, to followed 47.5% by C-section (28.2%) and vacuum assisted with none (24.3%), forceps delivery. 67.4% counselling to the family. described in the literature. care of a tertiary hospital were evaluated. A formulary was filled up of each newborn with the following items: gestational age, sex, mode of of neonates were exclusively breastfed with only 1 % being exclusively non-breastfed. didn’t 72.4% have any blood incompatibility but, when children with pathogenic variants performed microarray analyses and 30.0% (n=3) of them had the same genetic abnormality with (2 similar evaluate the threshold to initiate phototherapy making its use more judicious. (n=28) of the abnormalities were pathogenic, possibly (n=10) 15.9% pathogenic and (n=25) 39.7% variations of unknown significance Pathogenic(VOUS). microarray abnormalities were found in 25.5% of patients with dysmorphic features, with 12.8% with IDD and ASD. 7.2% and chi-square test. assure the restricted use and safety of phototherapy, with particular concern about long-term side effects. [email protected] anomalies/malformations not attributable to a known genetic syndrome, non-syndromic Intellectual Developmental Disorder and (IDD) Autism Ana Reis e Melo Andreia Ribeiro

Abstracts 100%; LR+,, 1.05; LR−, 0; AUC, 0.87) were discharged home while the patients with an initial WS ≥5 (sensitivity, 99%; specificity, 57%;LR+,, specificity, 99%; (sensitivity, WS ≥5 initial an with patients the while home 100%; LR+,, 1.05; discharged 0; were AUC, LR−, 0.87) These lesions were of probable inflammatory etiology, but without definitive conclusion, since the MRI findings offer a wide variety of differential differential of variety wide a offer findings MRI the since conclusion, definitive without but etiology, inflammatory probable of were lesions These THE INITIAL WESTLEY SCOREINPREDICTINGTHEOUTCOMEOFCROUP 416.35; AUC, 0.54; LR−, 0.90) 47%;LR+,, 97%; specificity, (sensitivity, wards the to admit to need may aWS ≥6 with PED. the Patients in 41.0; stay to require may 0.43) LR−, associated with Westley score (WS) and other clinical factors in predicting the outcomes in the pediatric emergency department (PED). department emergency pediatric the in outcomes the predicting in factors clinical other (WS) and score Westley with associated after 2 years, with no pathological findings described. During the investigation period the patient was asymptomatic, with normal psychomotor psychomotor normal with asymptomatic, was patient the period investigation the During described. findings pathological no with 2years, after in lesions as well as tubers, cortical of presence the confirmed which one, first the after days 4 performed MRI was AHigh-field ADEM. as somnolence, marked presented patient the At arrival, days. two previous the over episodes vomiting multiple following seizure, afebrile an correlation with the length of hospital stay(r=0.617, p<0.001). ROC analysis showed that patients with an initial WS <2 (sensitivity, 5%; specificity, 5%; specificity, (sensitivity, WS <2 initial an with patients stay(r=0.617, that showed hospital of analysis p<0.001). ROC length the with correlation of hospital stay were analyzed to predict clinical outcomes. We calculated all the areas under the receiver operating characteristic (ROC) curve (ROC) curve characteristic operating receiver the under areas the all We calculated outcomes. clinical predict to analyzed were stay hospital of diagnoses. The evolution of the patient’s condition was not typical of ADEM. of typical not was condition patient’s the of evolution The diagnoses. development. the and initiated, was ADEM of Treatment protocol performed. not was puncture alumbar why reason hypertension, intracranial of degree 1 Presentation Oral Wen Chieh Yang Chieh Wen Presentation Oral repeated 6 months later, without any abnormalities identified - the anticonvulsive medication was stopped-, and a High-field MRI was repeated repeated was MRI High-field a and stopped-, was medication anticonvulsive the - identified abnormalities any later, without 6months repeated medication was initiated. The patient was discharged and followed in outpatient consult, and no other findings expected in TS were obtained, obtained, TS were in expected findings other no and consult, outpatient in followed and discharged was patient The initiated. was medication no always what they seem - the interpretation of these results can sometimes lead the etiological investigation away from the correct condition, condition, correct the away from investigation etiological the lead sometimes can results these of interpretation -the seem they what always no Conclusion: astrong WS had initial The outcomes. clinical predicting WS for in factors major the were entry air and retraction whereas croup, severe with Conclusion: 22000/ul; Count Leukocyte (Total markers inflammatory increased revealed tests Blood exam. physical on findings relevant other without The authors report the case of a previously healthy 5-year-old male patient, admitted to the Emergency Department (ED) after (ED) after Department Emergency the to admitted patient, male 5-year-old healthy apreviously of case the report authors The report: Case cases. such of one describes report authors’ The time. through develops patient the how following after unveiled be can which C-reactive Protein 2.00 mg/dL). An initial Low-field MRI revealed findings compatible with ADEM, and did not exclude the possibility of some some of possibility the not exclude did and ADEM, with compatible findings revealed MRI Low-field initial An mg/dL). 2.00 Protein C-reactive CCH, Taiwan;CCH, [email protected] presence of multiple areas that appeared to be cortical tubers, as well as lesions in other areas that could point towards other diagnoses, such such diagnoses, other towards point could that areas other in lesions as well as tubers, cortical be to appeared that areas multiple of presence the described Neuroradiologist) a (by results MRI Low-field same the of report Alater 12 next hours. the over dramatically improved patient DISAPPEARING TUBERS,DIAGNOSIS– A CASE REPORT treatment. Result: wards. the to admission for need the WS discriminating initial of values cut-off the determine to length the WS, fever, in and age, factors PED. individual the The from croup with patients recruited We prospectively Method: and Population the thalamus and caudate nucleus. An Electroencephalography (EEG) revealed a very disorganized and altered trace, and anticonvulsive anticonvulsive and trace, altered and disorganized avery (EEG) revealed Electroencephalography An nucleus. caudate and thalamus the Pedro Pedro Marinho Background: ID: 274 10ID: /OP5: including skin lesions, renal, cardiac or ophthalmic abnormalities. Genetic testing was negative for mutations in TSC1 and TSC2. An EEG was EEG An was TSC2. TSC1 in and mutations for negative was testing Genetic abnormalities. ophthalmic or cardiac renal, lesions, skin including ID: 141ID: 9 /OP5: Introduction: Unidade de Saúde Local do Alto Minho, Hospital de Santa Luzia, Portugal; Portugal; Luzia, Santa de Hospital Minho, Alto do Local Saúde de Unidade OP5: PRESENTATIONS: ORAL 5 SESSION A total of 192 patients with croup were enrolled. Cyanosis and altered consciousness were not clinically significant even in patients patients in even significant clinically not were consciousness altered and Cyanosis enrolled. were croup with 192 of patients Atotal 20 9 t h Patients with an initial WS of 1 to 2 could be safely treated at home and those with initial WS >5 required hospitalization for further further for hospitalization required WS >5 initial with those and home at treated safely be 2could 1to WS of initial an with Patients The disappearance of the previously observed abnormalities in the initial MRI excludes the diagnosis of Tuberous Sclerosis. Sclerosis. Tuberous of diagnosis the excludes MRI initial the in abnormalities observed previously the of disappearance The

E Westley croup score has been generally used to assess the severity of croup. This study aimed to identify the individual factors factors individual the identify to aimed study This croup. of severity the assess to used generally been has score croup Westley In Medicine, decisions are often guided by results of diagnostic techniques, from blood tests to imaging. However, things are are However, things imaging. to tests blood from techniques, diagnostic of results by guided often are decisions Medicine, In D I T 1 1 , Raquel Oliveira , Raquel I O 7 N Topics: Topics: General Pediatrics, Neurology Pediatrics, General Emergency Pediatrics 1 , Ana de Carvalho Vaz Carvalho de Ana , CONFERENCE PROGRAMME ABSTRACTS 1 , Pereira Ângela

2 2 Hospital de Braga, Portugal; [email protected] Portugal; Braga, de Hospital , João Paulo Fernandes Paulo João , ORAL PRESENTATIONSORAL 2 , Mariana Costa 1 , Célia Barbosa Célia , 79 2

Abstracts 80

6 hrs 8910 3,58 21,6 2620 73,5 430 437000 13,1 12100 0,7 23 2250 72 hrs 70 441000 40,1 15,3 11,3 1670 10400 12,4 14700 POSTER SESSION 1 0.7 5350 8600 620 62,3 30 36 hrs 27,8 2390 256000 7,2 11 172

5020 66 38,9 34,9 316 24,9 24 hrs 1,3 1950 1250 11,1 1750 137000 52 90 3.5 2700 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE 45 43,4 12 hrs12 1,5 1170 1400 10,9 133000 186 Dermatology, Adolescent Wellbeing Dermatology Topics: Topics: , Ksenia Loseva 0.8 52.7 0 hrs 3430 3.8 27 41.5 1810 1420 11.7 141.000 113 130 N 7 O I 1 T I D Pityriasis Amiantacea is an uncommon (PA) clinical condition of the scalp. It usually occurs in children and is characterized by Acne is one of the most common diseases in adolescents. In serious cases treatment with isotretinoic has excellent outcome, , Isabel Ayres Pereira, Andreia Ribeiro, Marta Vila Real, Ana Cristina Oliveira, Eduarda Osório Ferreira E

We concluded We that our patient had SIRS, due to isotretinoic bone marrow suppression, possibly during the course of an upper h t Thursday, 07/Dec/2017: 1:00Pm - 2:00pm • Location: Mancini 3A Mancini 1:00Pm - 2:00pm • Location: 07/Dec/2017: Thursday, 9 20 PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: Time: Time: █ PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: Neut % Hb g/dl Lym % Lym Ur mg/dl PLT/μl Cre mg/dl CRP mg/dl WBC/μl Μono % Ν/μl Ν/μl Ν/μl █ back pain over 48hrs. From clinical examination he was in poor general condition with hyperpyrexia despite the use of antipyretics, tachycardia, Introduction: increasedserum urea and creatinine with further clinical and laboratory deterioration over the hours next 12 (table 1). Introduction: ID: 296 1 / PO1: ID: 224 2 / PO1: immediate clinical and laboratory improvement within the next hours. 24 There was concurrent acne lesions improvement. Purpose: alert To pediatric community in the safe isotretinoic use for acne treatment. treatment with antifungical shampoo and salicylic acid cream. Poster Presentation Effrossine Tsekoura Poster Presentation PA and alertPA Paediatricians for the clinical features of this condition, for a timely diagnosis and treatment. Patient was treated with broad-spectrum antibiotics as severe febrile neutropenia and systemic inflammatory reaction syndrome with(SIRS) PITYRIASIS AMIANTACEA: A CHALLENGING DIAGNOSIS IN PAEDIATRICS A AMIANTACEA: PITYRIASIS Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal; [email protected] was discontinued due to side effects. Blood tests showed severe leucopenia with neutropenia, thrombocytopenia, markedly elevated CRP, Case Report: old male yr. adolescent A 15 admitted in our casualty with an history of hyperpyrexia 39.9oC, abdominal pain, vomiting and lower were normal. The mycological cultural was negative. This findings were suggestive of seborrheic dermatitis. In this PA case,responded the to Case report: A two-year-old boy was referred to a Hospital Paediatric Dermatology Department with a four-month history of scalp Cátia Leitão Cátia Conclusion: noted in chest, back and face. He was on isotretinoic treatment for the last days. He 10 had received same medication 4 months ago, which masses of thick, adherent, silvery or yellowish scales, resembling asbestos fibers, surrounding and binding down tuffs Its of exacthair. etiology nevertheless with sometimes serious life threatening complications such as leucopenia, neutropenia and thrombocytopenia, SEVERE FEBRILE NEUTROPENIA IN ISOTRETINOIC ACNE TREATMENT AND UPPER AIRWAY INFECTION AIRWAY AND UPPER ACNE TREATMENT IN ISOTRETINOIC SEVERE FEBRILE NEUTROPENIA remains unclear but it is typically considered an exaggerated inflammatory pattern response that affects the scalp, mainly caused by seborrheic diffuse abdominal pain, pharyngitis, painful cervical lymphadenopathy, spleen and liver enlargement and anuria. Severe cystic acne lesions desquamation, without pruritus. His past medical and familial history were unremarkable. Examination of the scalp revealed thick, yellowish and dermatitis, psoriasis and tinea capitis. The diagnosis is clinical but mycological examination and cultures are useful. should Treatment be directed towards the causal dermatosis, and includes keratolitic agents, topical steroid and/or antifungical. The authors present a case report of Presentations details for the possible side effects of bone marrow suppression and the need for medical advice in cases of a febrile disease adherent scales, binding down tuffs of hair at frontoparietal regions, without erythema and alopecia. Nails and skin in other parts of the body Table 1 Table airway infection (pharyngitis). Isotretinoic treatment in acne despite excellent results must be used cautiously and patient must be informed in Asklepieion General Hospital Athens Greece, Greece; [email protected] POSTER SESSION 1

POSTER PRESENTATIONS

Abstracts – 1.033) were associated with preterm births. However, low birth weight was not associated with exposure to air pollutants. air to exposure with associated not was weight birth However, low births. preterm with associated – 1.033) were THE REPUBLICOFKOREA ㎍/m³ may increase the risk of preterm birth. Further research for the mechanism and education for pregnant women to avoid exposure are needed. are exposure avoid to women pregnant for education and mechanism the for research Further birth. preterm of risk the increase may ㎍/m³ air pollutant concentrations with World Health Organization criteria. Add to that, we compared the proportions between the first quartile and and quartile first the between proportions the compared we that, to Add criteria. Organization Health World with concentrations pollutant air after confirmation with a second dipstick test. Hypertension was detected in 5.6% (15/265) after 3 separate measurements. Body mass index index mass Body measurements. separate 3 5.6% in after (15/265) detected was Hypertension test. dipstick second a with confirmation after (less than 37weeks gestation) and low birth weight (less than 2,500 gram). 2,500 than (less weight birth low and gestation) 37weeks than (less enrolled. Morning mid stream urine samples were tested by dipstick. Children with abnormal findings were re-tested on another day. Height, day. Height, another on re-tested were findings abnormal with Children dipstick. by tested were samples urine stream mid Morning enrolled. calculated and matched to birth data by registered regions. We analyzed proportion of adverse birth outcomes between two groups by dividing dividing by groups two between outcomes birth adverse of proportion We analyzed regions. registered by data birth to matched and calculated give an indication of the primary skin disorder, which determines treatment modality. The Paediatric Dermatology should be involved in cases cases in involved be should Dermatology Paediatric The modality. treatment determines which disorder, skin primary the of indication an give commonest risk factor in this population. this in factor risk commonest concern and effects on many health problems. health many on effects and concern of initial treatment resistance or suspicion of other diseases. As Paediatricians, it is important to be informed of this disease and select patients patients select and disease this of informed be to important is it Paediatricians, As diseases. other of suspicion or resistance treatment initial of of Z-score >3 was documented in 2.2% (6/265). There was no statistically significant correlation between the risk factors and independent independent and factors risk the between correlation significant statistically no was There (6/265). 2.2% in documented was >3 Z-score of occasions if greater than or equal to 95th centile for age and height. and age for centile 95th to equal or than greater if occasions 1 1 study highlights the prevalence of risk factors for CKD in asymptomatic children; up to 11.7% in this study population. Hypertension is the the is Hypertension 11.7% to up population. children; study this in asymptomatic in CKD for factors risk of prevalence the highlights study rocketmail.com SO₂ 1.056 (aOR: (C.I. was CO 1.031, 1.046 –1.067) and C.I. 1.020 –1.041), O₃ (aOR: 1.139, C.I. 1.127 –1.152), PM10 and (aOR: 1.022, C.I. 1.012 risk factors for renal disease. renal for factors risk matter less than 10 micrometers in diameter (PM10) from 2009 to 2013. Mean concentration of each air pollutants during pregnancy were were pregnancy during pollutants air each of concentration 2013. to Mean (PM10) 2009 diameter in from 10 micrometers than less matter SURVEILLANCE OFCHRONICKIDNEY DISEASEIN A NIGERIANRURAL SETTING Conclusion: years. Risk factors for CKD (proteinuria, hypertension, obesity) were detected in 11.7% (31/265). Proteinuria was documented in 3.7% (10/265) in 11.7% in detected were documented was (31/265). obesity) Proteinuria hypertension, (proteinuria, CKD for factors Risk years. Conclusion: who should be referenced to Dermatology. to referenced be should who Conclusion: weight and blood pressure measurements were documented for the respective children. Blood pressure measurements were repeated on 3 3 on repeated were measurements pressure Blood children. respective the for documented were measurements pressure blood and weight modifiable important most the are obesity and proteinuria Hypertension, debatable. still is screening its of strategy the while accepted, widely variables (age and sex). (age and variables per annum. The effectiveness of its early detection and treatment to prevent progression to End Stage Renal Disease (ESRD) has become (ESRD) become has Disease Renal Stage End to progression prevent to treatment and detection early its of effectiveness The annum. per 2010 to 2013. We obtained concentration of sulphur dioxide (SO₂), nitrogen dioxide (NO₂), carbon monoxide (CO), ozone (O₃), and particulate (CO), (O₃), particulate ozone and monoxide (NO₂), carbon dioxide (SO₂), nitrogen dioxide sulphur of concentration 2010 2013. to We obtained MATERNAL EXPOSURETO AMBIENT AIR POLLUTANTS DURINGPREGNANCY AND ADVERSE BIRTH OUTCOMES IN Results: birth preterm on region each in pollution air of effect the assess to used was model regression logistic Amultivariate concentrations. of rest the Presentation Poster In this study, we analyzed association of adverse birth outcomes (preterm births, low birth weights) and ambient air pollutants. air ambient and weights) birth low births, (preterm outcomes birth adverse of association analyzed we study, this In Purpose: Presentation Poster Results: group. age this in CKD for factors risk the Hospital at Gangdong, Republic of Korea; [email protected] Korea; of Republic Gangdong, at Hospital Kene Ebuka Maduemem Ebuka Kene Purposes: A total of 1,802,925 records of singleton births were examined using the National Birth Registration Database, from from Database, Registration Birth National the using examined were births singleton of records 1,802,925 of Atotal Methods: and Materials Methods: ID: 189 /PO1: 189 ID: 4 Introduction: In Gyu Song Gyu In ID: 148 /PO1:ID: 3 Introduction: Kyung Hee Universitiy Hospital, Republic of Korea; Korea; of Republic Hospital, Universitiy Hee Kyung Cork University Hospital, Cork, Ireland; Ireland; Cork, Hospital, University Cork PO1: POSTER PRESENTATIONS: 1 SESSION The adjusted odds ratio (aOR) of PM10 over 70㎍/m³ for preterm birth was 1.530 (C.I. 1.436 – 1.630). The aOR of highest quartile of of quartile (C.I. 1.530 highest of was 1.436 –1.630). aOR The birth (aOR) PM10 of preterm ratio for 70㎍/m³ over odds adjusted The Early morning urine was available for urine dipstick test in 265 children: 141 (53.2%) males. The median age was 6.30 (0.43 –16.48) (0.43 6.30 was age median 141 The children: males. 265 (53.2%) in test dipstick urine for available was urine morning Early A cross-sectional descriptive study was conducted in a rural community in the South Eastern part of Nigeria. 280 children were were children 280 Nigeria. of part Eastern South the in community arural in conducted was study descriptive Across-sectional To evaluate the usefulness of community based screening tools for early identification of CKD in children. To educate the public on on public the educate To children. in CKD of identification early for tools screening based community of To usefulness the evaluate 20 9 t h Maternal exposure to ambient air pollutants during pregnancy was associated with preterm birth. Especially, expose to PM10 to 70 over expose Especially, birth. preterm with associated was pregnancy during pollutants air ambient to exposure Maternal PA is a distinctive inflammatory condition but often under-recognized by Paediatricians. A detailed examination of all the skin may may skin the all of examination detailed A by Paediatricians. under-recognized often but condition inflammatory PA adistinctive is Screening for modifiable risk factors for CKD will result in early detection of renal disorders in childhood. This community based based community This childhood. in disorders renal of detection early in result will CKD for factors risk modifiable for Screening

E 1 During recent years, air pollutants were important social issues in the Republic of Korea. Air pollution is a major global health health global amajor is pollution Air Korea. of Republic the in issues social important were pollutants air years, recent During Chronic kidney disease (CKD) is a worldwide public health problem. In Nigeria, incidence in children ranges between 2-6 cases cases 2-6 between ranges children in incidence Nigeria, In problem. health public (CKD) aworldwide is disease kidney Chronic D , Min Sun Kim Sun , Min I T 1 I O 7 N Topics: Topics: 1,3 , Nnaemeka Akubue , Nnaemeka 2 , Yong-Sung Choi , Yong-Sung NICU Epidemiology CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 2 University of Nigeria Teaching Hospital, Enugu, Nigeria; Nigeria; Enugu, Hospital, Teaching Nigeria of University 1 , Sung-Hoon Chung , Sung-Hoon 2,3 , Ekene Umego , Ekene 2 Seoul National University Hospital, Republic of Korea; Korea; of Republic Hospital, University National Seoul

3 , Ogochukwu Maduekwe , Ogochukwu 3 , Chong-Woo Bae , Chong-Woo POSTER SESSION 1 SESSION POSTER 3 3 3 Global Missions Ireland; ebukakene@ Ireland; Missions Global 3 Kyung Hee University University Hee Kyung 81

Abstracts 82 3 POSTER SESSION 1 Department of Community Medicine,Faculty 2 , Pujitha Wickramasinghe 2 Kyung Hee Universitiy Hospital, Korea, Republic of (South Korea); 2

2 , Dulani Samaranayake Dulani , 1 Department of Paediatrics, Faculty of Medicine, University of Colombo, Sri Lanka; 3 , In Gyu Song 1 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE , Eresha Jasinge 1 General Pediatrics, Obesity & Physical Activity Rare Diseases, Management , Juyoun Yu 1 Topics: Topics: N 7 O I 1 T I , Cho Hee Kim D 1 Hyperuriceamia has emerged as an importantmetabolic marker of non-communicable diseases and have foundthat uric acid Despite significant advances in disease treatment, resources for the pediatric palliative forcare (PPC) children with serious E

VAI and had UA a significant VAI association between each other in addition to the association they both showed with obesity Our study showed pediatric doctors in Korea have low preferences for children to LSTs in the terminal state and perceive the h t 9 20 Of the 205 obese were children metabolically 137 9.80 (mean age (2.0)), (SD) abnormal. Compared with metabolically normal A total of 118 doctors A total responded of 118 to the survey. The median age was 37 years, 53% were female and 76%answered they have own PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: Department of Chemical Pathology, Lady Ridgeway Hospital, Colombo, Sri Lanka; Seoul National University Hospital, Korea, Republic of (South Korea); Introduction: ID: 245 5 / PO1: / PO1: 6 ID: 247 / PO1: Introduction: half of the respondents answered that they are not confident about advance care planning including LST decisions. Most respondents reported illnesses are limited in South Korea. The obstacles to provide optimal include PPC inadequate funding, shortage of specialized professionals, is incurable and in the deteriorating state, more respondents showed (29%) preferences for children to LSTs in the same situation. More than Materials and Methods: A cross-sectional analyticalstudy was conducted among year-old obese 5-15 children (BMI for age >+2SD of median Min Sun Kim Materials and Methods: The study survey was developed based on a review of the palliative care literature and sample physician interview. A Dinesha Maduri Vidanapathirana Maduri Dinesha Purpose: investigate To the relationship between and hyperuriceamia VAI among metabolically abnormal obese Sri Lankan children and to Poster Presentation Poster Presentation Results: Purpose: This study explored pediatric doctors’ perception of end-of-life care and needs on in PPC Korea. Results: PHYSICIAN PERSPECTIVES ON END-OF-LIFE CARE AND PEDIATRIC PALLIATIVE CARE FOR CHILDREN IN THE PALLIATIVE AND PEDIATRIC CARE PHYSICIAN PERSPECTIVES ON END-OF-LIFE REPUBLIC OF KOREA plasma mmol/L); glucose HDL(<1.03 triglyceride or mmol/L). 2 hour (>100mg/dL) RBS (FPG) Metabolically (>140mg/dL); (≥1.7 abnormal obese child Conclusion: which are not reflected by anthropometry. Visceral adiposity indexis formulated (VAI) using anthropometry (Body mass index (BMI) andWaist was defined as someone having abnormality in two or more of the above parameters. Insulin resistancewas assessed using HOMA-IR. were measured. The considered obesity associated metabolic abnormalities were WC-SDS Systolic (>+2SD), and Diastolic BP (>+2SD),fasting Conclusion: [email protected] needs The of PPC. results will guide the health authorities to design program PPC in Korea. related metabolic abnormalities. was a strong VAI predictor levels of UA that were associated with the presence oftwo or more obesity related CENTRE IN SRI LANKA significant. However metabolically abnormal HOMA-IR were compared 1.1±0.5), withvs (2.35±1.6 VAInormal vs 2.9±0.6),WC-SDS (3.14±0.6 significant ROC At a curve cut-offandVAI had 1.98withspecificityAUCsensitivity 0.715. of of of of in77.1% 60.4% predicting hyperuricaemia. [email protected] started when a child is diagnosed with incurable diseases, and 48% said advance care planning is needed in a state of constant deterioration six months. Pediatric doctors indicated to the barriers to pediatric palliative care implementation as follows: the attitude of parents who prefer refer a patient to (10%). PPC 1 1 circumference and metabolic (WC)) effects (Triglyceride and (TG) Its HDL). usefulness is not validated in Sri Lankan children. compare the risk predictive ability for hyperuriceamia between and other VAI obesity indices including BMI, waist-to-height WC, ratio (WHtR). of Medicine, University of Colombo, Sri Lanka; questionnaire was sent via online survey and mail to the pediatric doctors with specialized boards working at 43 tertiary hospitals in South Korea. child. Eighty percent responded that, in the previous 2 years, they cared for more than one pediatric patient who died. When asked about years and old 15 12, respectively.over 7, 4, As for the life-sustaining treatments decision, answered (LSTs) 24% that discussions should be group, theabnormal group BMI-SDS had higher (2.8±0.6 but was vs 281±70.1µmol/L) not levels vs 2.7±0.7) statistically (286±71.5 of UA (UA) levels(UA) in obese individuals are quite high. More than the total adiposity, certain patterns of distributions are related to metabolic defects, (WHO standards)). After a 12-hour overnight fast, blood was drawn for glucose,lipid profile, insulin UA.and OGTTwas done with anhydrous glucose (3.2±1.9 vs 2.5±2.3), TG (1.4±0.7 vs 0.9±0.3 vs 2.5±2.3),(3.2±1.9 (1.4±0.7 mmol/L), TG and HDL (0.9±0.2 vs 1.3±0.2 mmol/L) showed statistically significant differences.UA even though actual death is not expected. Although only 7% of pediatric doctors had personal desire when for use their of LSTs own disease experiencing difficulties PPC in areas such as symptom management, ethical problems, and psychosocial support more than onceevery lack of financial(16%), inadequatesupport (12%), linkage forPPC between curative and andpalliative difficulties(12%), care to decide when to abnormal metabolic parameters. and VAI showedand VAI significant correlations with metabolic parameters but not with anthropometric indices. ROC curves were developedVAI for and anthropometric indicators in predicting hyperuricaemia in obese children with two or more metabolic abnormalities. showedOnly VAI a and healthcare system, but the perception of health professionals is also very important. appropriate age for terminal state disclosure, 6%, 30%, answered 42% and that 14% pediatric patients should be informed if they are aged aggressive shortage treatment of professionals PPC (19%), and organizations negative perception (18%), on among PPC health professionals ASSOCIATION OF VISCERAL ADIPOSITY INDEX WITH SERUM URIC ACID IN OBESE CHILDREN IN A TERTIARY CARE TERTIARY A ACID IN OBESE CHILDREN IN INDEX WITH SERUM URIC ADIPOSITY OF VISCERAL ASSOCIATION 1.75g/kg body1.75g/kg weight Random (max 75g). plasma glucose and (RPG) insulin was done 2 hours Height, later. weight, and WC blood pressure (BP)

Abstracts AUTISM AS A “NARCISSISTIC”DISORDER:SOCIAL IMPLICATIONS January 2015. The patients were categorized into guidelines used and non-guidelines used group. Matched case-control 1:1 by propensity 1:1 propensity by case-control Matched group. used non-guidelines and used guidelines into categorized were 2015. patients The January Amalia Megremi Amalia and ER revisited rate within 7days. within rate ER revisited and autistic characteristics are a deficiency in prosocial behavior (a form of social behavior aimed at the benefit of other people or society as a as society or people other of benefit the at aimed behavior social of form (a behavior prosocial in adeficiency are characteristics autistic are heading towards societies where egocentrism, narcissism, callous-unemotional behavior, lack of friendship and affection will be dominant. dominant. be will affection and friendship of lack behavior, callous-unemotional narcissism, egocentrism, where societies towards heading are altruism, cooperation and reciprocal help will be dominant (social benefit). (social dominant be will help reciprocal and cooperation altruism, only not intervene), early (and infants in deficiency behavior prosocial of characteristics early the detect timely to professionals health and exacerbation patients (5.7% vs. 31.6%, p=0.005). Time to first inhaled bronchodilator (10 min vs. 13 min, p=0.037) and systemic steroid (51min steroid systemic and p=0.037) (10 vs. min, min 13 bronchodilator inhaled first to Time (5.7% 31.6%, vs. p=0.005). patients exacerbation extremity joint range of motion (EHA) measurements were performed with a goniometer and hand functions were assessed using the Jebsen Jebsen the using assessed were functions hand and a goniometer with performed were (EHA) measurements motion of range joint extremity CRUS. with achild in balance on deformities extremity upper of effects empathy, friendship, affection for others, help, sharing and cooperation are handicapped areas. Research has revealed the anatomical and and anatomical the revealed has Research areas. handicapped are cooperation and sharing help, others, for affection friendship, empathy, child can perform daily activities. Upper extremities movements can affect on standing and balance. The aim of the study is to examine the the examine to is study the of aim The balance. and standing on affect can movements extremities Upper activities. daily perform can child the while cupboard, the from drinking face, the washing eating, as such activities, some in difficulty have CRUS with Children forearm. the of oxytocin as a neurotransmitter play a predominant role in these functions and both are disturbed in autism. in disturbed are both and functions these in role apredominant play aneurotransmitter as oxytocin developmental transition from the “self” (egocentric approach) to the “other” (allocentric approach). So, autism is a “narcissistic” disorder where where disorder a“narcissistic” is autism So, approach). (allocentric “other” the to approach) (egocentric “self” the from transition developmental CHILDREN PRESENTEDTO EMERGENCY ROOMWITH ASTHMA EXACERBATION severity. Early systemic steroid and bronchodilator administration seems to be contributing factors. contributing be to seems administration bronchodilator and steroid systemic Early severity. score matched using 7 covariates. Comparisons were made between 2 groups in terms of admission rate, ICU admission rate, time spent in ER ER in spent time rate, admission ICU rate, admission of terms in 2groups between made were Comparisons 7covariates. using matched score ER may in asthma pediatric of management appropriate is hypothesis Our effectiveness. guidelines’ To R-PAAM the evaluate Objective: succeed, he eventually drowned. Early characteristics of autistic children are reduced eye contact, inability to share not only a game but also also but agame only not share to inability eye contact, reduced are children autistic of characteristics Early drowned. eventually he succeed, [email protected] Greece; Aegean, the of University were matched and divided into case-control. Admission rate (28% vs. 44%, p=0.041) was lower in guideline-used group, especially in mild mild in especially group, guideline-used in p=0.041) lower was 44%, (28% vs. rate Admission case-control. into divided and matched were whole through help, sharing and cooperation) and empathy. The deficiency in prosocial behavior observed in autism reflects the failure of failure the reflects autism in observed behavior prosocial in deficiency The empathy. and cooperation) and sharing help, through whole Conclusion: A 7-year-old male patient with CRUS was admitted to the physical therapy unit who have not undergone a surgery. Upper Upper asurgery. undergone not have who unit therapy physical the to admitted was CRUS with patient male A7-year-old Report: Case Conclusions: vs. 62 min, p=0.039) were also shorter in guideline-used group. ICU admission rate (4% vs.6.7%, p=0.467), time spent in ER (88 min vs. 95 min, min, 95 vs. min ER (88 in spent time (4% rate p=0.467), vs.6.7%, admission ICU group. guideline-used in shorter also were p=0.039) min, 62 vs. prevent hospitalization. p=0.368), and revisited rate within 7 days (7.4% vs. 4.8%, p=0.595) were not significantly different amongst the two groups. two the amongst different significantly not were (7.4% 7days p=0.595) within rate 4.8%, vs. revisited and p=0.368), EFFECTIVENESS OFRAMATHIBODI PEDIATRIC ASTHMA GUIDELINEONTHEHOSPITALIZATION RATES OF BALANCE EVALUATION IN A CHILDWITHCONGENITAL RADIOULNARSYNOSTOSIS Faculty of Medicine Ramathibodi Hospital, Mahidol University, Thailand; [email protected] Thailand; University, Mahidol Hospital, Ramathibodi Medicine of Faculty Presentation Poster Results: Presentation Poster to love – that he wanted to touch it. This was impossible since, as soon as his hand touched the water, it dissolved. In his insistence to to insistence his In water, dissolved. the it touched hand his as soon as since, impossible was This it. touch to wanted he –that love to managed he thing only the it was – enchanted so was and spring of a waters the in reflection his saw he day One Echo. Nymph the of love the Results: emerge. to aspects new for essential is It Purpose: Does, like Narcissus of Greek Mythology who was deaf to the call of the enamoured with him Echo until he died admiring himself in the river, river, the in himself admiring died he until Echo him with enamoured the of call the to deaf was who Mythology Greek of Narcissus like Does, Background: Hand Function Test (JHFT). The balance was assessed with the Biodex Balance System® (BBS) and limits of stability (LoS), and modified modified (LoS), and stability of limits and (BBS) System® Balance Biodex the with assessed was balance Test The (JHFT). Function Hand Varol Kepenek Busra Presentation Poster parents for imperative is it Thus, altruism? and help reciprocal affection, for request the to society of indifference the reflects autistic modern the Uthen Pandee Method: 2013. since developed was guideline (R-PAAM) Management Bezmialem Vakif University, Turkey; [email protected] University, Vakif Bezmialem Literature review. Literature Methods: and Material interests or emotions, while later they may develop difficulties in understanding the feelings and intentions of others (theory of mind). These These mind). of (theory others of intentions and feelings the understanding in difficulties develop may they later while emotions, or interests ID: 172 /PO1:ID: 8 ID: 174ID: /PO1: 7 Introduction: Introduction: ID: 222 /PO1: 9 222 ID: biological basis of neural circuits involved in empathy and prosocial behavior. The anterior cingulated cortex as an anatomical structure and and structure anatomical an as cortex cingulated anterior The behavior. prosocial and empathy in involved circuits neural of basis biological because it leads to timely detection of autistic disorder (personal benefit), but also because it contributes to the creation of societies where where societies of creation the to contributes it because also but benefit), (personal disorder autistic of detection timely to leads it because PO1: POSTER PRESENTATIONS: 1 SESSION Retrospective chart review acute asthmatic attack pediatric patients whom visited ER at Ramathibodi hospital since April 2011 April to since hospital ER Ramathibodi at visited whom patients pediatric attack asthmatic acute review chart Retrospective The total of 385 ER visits was recruited. Sixty four percent had mild exacerbations (clinical scores 0-3). One hundred fifty visits visits fifty hundred One 0-3). scores (clinical exacerbations mild had percent four Sixty recruited. was ER visits 385 of total The At mythology, Narcissus was a handsome young man who was indifferent to the love expressed by others and did not respond to to respond not did and others by expressed love the to indifferent was who man young ahandsome was Narcissus At mythology, 20 9 t h R-PAAM guideline seems to be the hospitalized-reduction tool for pediatric patients who had exacerbation, especially for mild mild for especially exacerbation, had who patients pediatric for tool hospitalized-reduction the be to seems guideline R-PAAM

E Asthma exacerbation remains common problems in emergency rooms (ER) worldwide. Ramathibodi’s Pediatric Acute Asthma Asthma Acute Pediatric Ramathibodi’s (ER) worldwide. rooms emergency in problems common remains exacerbation Asthma Congenital radioulnar synostosis (CRUS) is a rare malformation that causes restriction of supination and pronation movements movements pronation and supination of restriction causes that malformation (CRUS) arare is synostosis radioulnar Congenital ASDs are increased and etiopathogenesis is unidentifiable. is etiopathogenesis and increased are ASDs According to the above and given that the incidence of autism is growing dramatically today, the question arises whether we we whether arises question today, the dramatically growing is autism of incidence the that given and above the to According D I , Koonkoaw Roekworachai, Wiparat Manuyakorn, Harutai Kamalaporn Harutai Manuyakorn, Wiparat Roekworachai, , Koonkoaw T 1 I O 7 N , Zeynep Hosbay , Zeynep Topics: Topics: Topics: Child Mental Health Allergy, Immunology & Pulmonology, Emergency Pediatrics Emergency &Pulmonology, Immunology Allergy, General Pediatrics, Rare Diseases Rare Pediatrics, General CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER

POSTER SESSION 1 SESSION POSTER 83

Abstracts 84 , Gideon 1 , Gila Meirson 1 , Olga Mandelgeim 1 POSTER SESSION 1

, Svetlana Buslovich Khayumov Buslovich Svetlana , 1 , Ilona Brants Ilona , 1,2 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE Clalit Health Services, Israel; [email protected] Services, Health Clalit Israel; 2 Emergency Pediatrics Emergency Dermatology, Allergy, Immunology Pulmonology & , Elzbieta Maciorkowska Topics: Topics: 1 N 7 O I 1 T I D Focusing on prevention efforts of unsupervised medication ingestion with the highest hospitalization rates may efficiently impact Chronic spontaneous urticaria is (CSU) a mast cell-driven disease characterized by the development of wheals, angioedema, or In Israel there are approximately 180,000 Pediatric Emergency Department visits, (PED) 25,000 admissions and deaths 150 E , Bat-Hen, AnnieLeviDaviko

It was observed that he had difficulty in subtests of JHFT particularly as writing, page turning and feeding. Compared to the JHFT Clinical analysis of chronic urticaria and dermatitis as a result of levothyroxine treatment in a two-year-old girl is associated with 1 h t 9 20 , Ilan Dalal Ilan , During that period, two hundred and forty poisoning four (244) agents were identified 199more patients.in than (17%), In 34/199 1 PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: Wolfson Medical Israel; Center, both for >6 weeks. The point prevalence for CSU is estimated The prevalence to be 0.5%-1%. of CSU in children The is prevalence 0.1%-0.3%. ID: 225 10 / PO1: Izabela Roszko-Kirpsza Introduction: hypothyroidism and subclinical hypothyroidism have been reported in 0% to 42.6% in CSU patients, and 0% to 31% respectively. The / PO1: 11 ID: 155 / PO1: Introduction: in patients with CSU ranged from 0% to 54.5%. Thyroid dysfunction is more common in adult patients with CSU than in children. Clinical light and heavy object. In the balance tests performedwith BBS, our case’s scores were considerably lower than the goal scores. The forces lesions disappeared without any recurrences noticed over the 5 months follow-up. The child is currently on a general diet. Medical University of Bialystok, Poland; [email protected] Materials & Methods: In this prospective ongoing study, and as a part of the National Pediatric Injury & Safety Surveillance (NAPIS) Medication and by Household Agent codes. The population includes patients aged years, 0–18 seen in Wolfson Medical Center during PED Hila WienerHila Poster Presentation Karplus Poster Presentation Purpose: The purpose of this study is to characterize all our unintentional PED poisoning cases. This could help identify prevention priorities the state of euthyreosis. Family history of thyroid disease negative. The patient was started on levothyroxine therapy After μg/day). (25 4 weeks of treatment with levothyroxine, the control fT3-4.0. studies μIU/l; showed After fT4-1.5; TSH-1.3 six weeks of treatment with levothyroxine, urticarial to unintentional injuries. The minimal data set is (MDS) based on the WHO recommendations. In addition,we have used the Poisoning by Results: thyroid disease, which is in agreement with the recent literature. forearm pronation angle was measured as 90º, supination 0º and left forearm pronation angle 80º, supination -80º. The results of LoS with BBS 2008-2016. Cases of intentional injuries were excluded. prevalence of clinical hypothyroidism in children In studies with published CSU was from 0% to 1.1%. the so treatment far, of hypothyroidism program, in we, collaboration with the Beterem organization, have created a computerized system for collecting data for all the visits PED due health. public Center, thereCenter, are almost 30,000 consults annually with approximately 50% pediatriccases. Poisoning is considered a major cause of death upper extremity dysfunction will affect the treatment positively, and increase the quality of life of the patient. Conclusion: weight g. 2 570 Infant range of normal course. In the treatment of urticaria, the family doctor used an elimination diet (non-dairy, without eggs) and Case Report: A 2-year-old girl was admitted to the Department of Allergology for a 5-month urticaria. Cutaneous lesions were presented every Conclusions: were evaluated as “directional control”transition forward backward 19, 68, left and right 29 (the goal scores for transition forward, left andwere right 65 and for transition bacward was BBS 30). m-CTSIB test were evaluated witheyes open-closed firm surface, andeyes open-closed firm Conclusion: negative, Helicobacter pylori antigen stool test-negative, The (negative). IgG-1.4index concentration Anti-Toxocara of TSH-63.32μIU/l (0.85-6.5μIU Surprisingly, girls compared were (58%), more common to only boys. 83/199 The (42%) most - 118/199 common poisoning agents were: results of healthy children of the same age group, our (Baegley case SB, was 2016), completed the subtest in longer periods, except for the surface. The sway index according to composite score of m-CTSIB were found 2.02 (the goal mean score was 0.81). CHRONIC URTICARIA AND HYPOTHYROIDISM IN A 2-YEAR-OLD GIRL A AND HYPOTHYROIDISM IN CHRONIC URTICARIA CHARACTERIZING UNINTENTIONAL POISONING CASES AT THE PEDIATRIC EMERGENCY DEPARTMENT AT AT DEPARTMENT EMERGENCY THE PEDIATRIC AT POISONING CASES CHARACTERIZING UNINTENTIONAL / l), antithyroid/ l), peroxidase-14.4IU/ml antithyroglobulin(negative), antibodies In <10.0IU/ml the (negative). thyroid ultrasound study - struma in 1a 1 day. Childday. was born of pregnancy II, normal, childbirth II, by cesarean section, points 10 on Apgar at 41hbd, scale. Child was born with birth count (WBC 8.38x103 peripheral Hb-13.4g/dl, / μl), MCV-78.6fl; blood eosinophilia-1.0%(absolute eosinophilia-0.08x103/ml), levels of serum complement components C3 and C4 – normal. Sensitization (presence of specific IgE)(Polycheck) to apple -2.5kU/l(f49) (class 2) and pork of hypothyroidism in the general population is 3.05%-4.6%. The prevalence of thyroid dysfunction (hypothyroidism and/or hyperthyroidism) on the rise despite widespread use of child-resistant packaging and the efforts of educational caregivers. According to the National Toxicology clinical test of sensory interaction integration (m-CTSIB) tests were performed. The results times (seconds) of subtest of the JHFT were objects and 3.78 3.4, heavy objects 2.96 and 2.85 for non-dominant and dominant hand respectively. According to “Neutral 0 Method”, the right (f26) -0.59IU/ml allergens (class 1) was found. Serum IgA concentration -0.6g/l (0.45-1.35g/l). Anti-transglutaminase (tTGA-IgA) and DGP/Ab-IgG - evaluated as writing 39 and 49.97, page turning 7.6 and 9.08, small objects 9.81 and 6.41, feeding 17.11 and 14, checkers 5.12 and checkers 4.36, and lightevaluated 14, 5.12 as writing page and turning 39 9.08, and small 49.97, 7.6 objects feeding 17.11 and 9.81 6.41, WOLFSON HOSPITAL BETWEEN 2008 AND 2016 BETWEEN 2008 WOLFSON HOSPITAL and moments brought by upper extremity movements can affect standing and balance. thinkWe that balance assessment in patients with antihistamines (cetirizine) without clinical improvement. The work up for chronic urticaria included the following: blood tests for complete blood annually due to unintentional injuries. visits PED and subsequent hospitalizations of children after unsupervised ingestion of medication are among these patients. and create intervention strategies. and euthyroid CSU patients has resulted in improvement or remission of CSU. antipyretic medications The most (20%). common place of intoxication was at home (80%). 1 agent was involved. Drugs were of the involved cases. in 97.8% As expected, were the under majority 75%) the age of 5 years. (150/199,

Abstracts Demonstrations of testing water, installing filters, and cleaning aerators were given in videos. in given were aerators cleaning and filters, water, installing testing of Demonstrations water: contaminated to exposure of • Prevention to baby. Types and food of mother the on lead of effects the and contamination lead on focused session The contamination: water • Lead folic of use diet, ahealthy of importance the on focused session The day: one pregnancy ahealthy have to oneself of care take to • How 10 YEAR-OLD GIRL WITHJUVENILE ARTHRITIS AND ALPHA-1 ANTITRYPSIN DEFICIENCY acid, and regular exercise. regular and acid, antitrypsin that is approximately 10-20% of normal [Stoller et al. 2007] and are at high risk for both severe liver and lung damage. lung and liver severe both for risk high at are and 2007] al. et [Stoller normal of 10-20% approximately is that antitrypsin alpha-1 of concentration aserum have usually genotype PI*ZZ with 2013]. al. et Individuals [Stoller diagnosed currently are people affected PI*SS. and PI*ZZ, are PI*SZ, genotypes common most SERPINA1 the and in gene, mutations point by caused is deficiency antitrypsin and had health insurance. A higher percentage of women answered true/false and multiple-choice answer questions on lead correctly at follow- at correctly lead on questions answer multiple-choice and true/false answered women of percentage Ahigher insurance. health had and (genotype PI*ZZ). In later years disease went into remission and no pharmacological therapy was necessary. Currently patient is 10 years old. old. 10 is years patient Currently necessary. was therapy pharmacological no and remission into went disease years later In PI*ZZ). (genotype turned which serum, in level antitrypsine alpha-1 test to decided was It ASAT noticed. was (ALAT U/l, –84 U/l) –59 enzymes liver of elevation consume if exposed to lead were discussed. were lead to exposed if consume of and two weeks after the end of the intervention to investigate changes in knowledge, skills, and behaviors. The online course consisted of of consisted course online The behaviors. and skills, knowledge, in changes investigate to intervention the of end the after weeks two and of out to be decreased. Molecular genetic testing was done and mutation PI*Z of the SERPINA1 gene was found in the homozygous form form homozygous the in SERPINA1 found was the PI*Z of gene mutation and done was testing genetic Molecular decreased. be to out diagnosed with juvenile idiopathic arthritis. Therapy with nonsteroidal anti-inflammatory drug was initiated. Four months after first admission, admission, first after months Four initiated. was drug anti-inflammatory nonsteroidal with Therapy arthritis. idiopathic juvenile with diagnosed compared to 88.8% (24 of 27) at follow-up. (24 at 27) of 88.8% to compared development of a randomized-controlled trial on the influence of an improved intervention on healthy behaviors and pregnancy outcomes. pregnancy and behaviors healthy on intervention improved an of influence the on trial arandomized-controlled of development 1 1 Water Crisis (2000-2004), exposure to lead-contaminated drinking water was associated with fetal death and reduced birth rates. birth reduced and death fetal with associated was water drinking lead-contaminated to exposure (2000-2004), Crisis Water range. Most recent ultrasound shows bursitis in right knee. For disease control it is necessary to choose medications without hepatotoxicity. without medications choose to necessary is it control disease For knee. right in bursitis shows ultrasound recent Most range. range of motion in right knee, subcutaneous tissue atrophy in both upper and lower legs, and soft-tissue swelling of both ankles. Girl was was Girl ankles. both of swelling soft-tissue and legs, lower and upper both in atrophy tissue subcutaneous knee, right in motion of range Genotype PI*ZZ is present in 95% of individuals with clinical manifestations [de Serres & Blanco 2012] although less than 10% of severely 10% severely of than less 2012] although &Blanco [de Serres manifestations clinical with individuals of 95% in present is PI*ZZ Genotype In addition, 25.9% of participants (7 of 27) stated they were confident/very confident in installing a lead water filter on a kitchen sink at baseline baseline at sink kitchen a on filter water lead a installing in confident confident/very were they stated 27) of (7 participants of 25.9% addition, In wished to become pregnant in the next 2 years were recruited via email, classroom contact, and flyers. A survey was administered at the start start the at administered was survey A flyers. and contact, classroom email, via recruited were 2years next the in pregnant become to wished when it comes to choosing disease-modifying antirheumatic drugs. antirheumatic disease-modifying choosing to comes it when Conclusion: with rheumatoid arthritis during phagocytosis of immune complexes, and it may promote severe joint destruction [Cox et al. 1980]. Alpha-1 1980]. Alpha-1 al. [Cox et destruction joint severe promote may it and complexes, immune of phagocytosis during arthritis rheumatoid with up compared to baseline. For example, at baseline, 77.8% of females (21 of 27) correctly answered the question “Eating food high in calcium, calcium, in high food “Eating question the answered (21 correctly 77.8% 27) of females of baseline, at example, For baseline. to compared up A 2-year-old girl was first admitted to hospital with a swollen right knee. Ultrasound revealed bilateral prepatellar bursitis. bursitis. prepatellar bilateral revealed Ultrasound knee. right swollen a with hospital to admitted first was girl A2-year-old report: Case Conclusion: Gergana D. Kodjebacheva Gergana RELATED TO SAFEWATER DRINKING AMONG WOMENOFREPRODUCTIVE AGE Reduced concentrations of alpha 1-antitrypsin may be insufficient to inhibit the proteolytic enzymes released into the joints of patients patients of joints the into released enzymes proteolytic the inhibit to insufficient be may 1-antitrypsin alpha of concentrations Reduced Rheumatoid factor, antinuclear antibodies, anti-nDNA antibodies and HLA B27 antigen were negative. However, there were positive parvovirus parvovirus positive were However, there negative. were antigen B27 HLA and antibodies anti-nDNA antibodies, antinuclear factor, Rheumatoid LEAD EXPOSURE AND PREGNANCY: AN INTERVENTION TO IMPROVEKNOWLEDGE,SKILLS, AND BEHAVIORS Presentation Poster these sessions: A web-based intervention was implemented and tested to increase knowledge and skills related to lead water contamination and and contamination water lead to related skills and knowledge increase to tested and implemented was intervention Aweb-based Purpose: Results: Presentation Poster Lately, she has been complaining about pain in right knee. Laboratory tests reveal vitamin D deficiency, but liver enzymes stays within normal normal within stays enzymes liver but Ddeficiency, vitamin reveal tests Laboratory knee. right in pain about complaining been has she Lately, Marta Laizane Marta The intervention used a one-group pre-test design. University of Michigan - Flint female students aged 18 to 45 who 18 who 45 to aged students female -Flint Michigan of University design. pre-test aone-group used intervention The Methods: and Materials B19 IgM antibodies. Two months later patient returned to hospital with complaints of pain in both knees. Physical examination showed limited limited showed examination Physical knees. both in pain of complaints with hospital to returned patient Two later months B19 antibodies. IgM improve behaviors related to safe drinking among females of reproductive age. reproductive of females among drinking safe to related behaviors improve ID: 250 /PO1: 12 250 ID: Introduction: health sciences; Genesee County Health Department; Department; Health County Genesee sciences; health Introduction: iron and vitamin C may help protect the pregnant woman and her unborn baby from lead poisoning” compared to 96.3% (26 of 27) at follow-up. follow-up. at (26 27) of 96.3% to compared poisoning” lead from baby unborn her and woman pregnant the protect help Cmay vitamin and iron ID: 201 /PO1: 13 201 ID: blood lead levels during pregnancy are associated with spontaneous abortion, lower birth weight, and infant mortality. During the Washington DC DC Washington the During mortality. infant and weight, birth lower abortion, spontaneous with associated are pregnancy during levels lead blood 2 University of Michigan - Flint, Department of public health and health sciences; University of Michigan - Ann Arbor, International institute; institute; International Arbor, -Ann Michigan of University sciences; health and health public of Department -Flint, Michigan of University University of Latvia, Latvia; Latvia; Latvia, of University University of Michigan - Flint, Department of public health and health sciences; sciences; health and health public of Department -Flint, Michigan of University PO1: POSTER PRESENTATIONS: 1 SESSION A total of 27 women completed the course. Most women were White/Caucasian, were either married or in a committed relationship, relationship, acommitted in or married either were White/Caucasian, were women Most course. the completed women 27 of Atotal 20 9 t h Alpha-1 antitrypsin deficiency is a rare coincidence with JIA, may be a risk factor for development of JIA and also a challenge challenge a also and JIA of development for factor risk be a may JIA, with coincidence rare is a deficiency antitrypsin Alpha-1 Knowledge about lead and strategies to prevent exposure to lead increased from pre- to post-test. This study may assist in the the in assist may study This post-test. to pre- from increased lead to exposure prevent to strategies and lead about Knowledge

E The Flint, Michigan Water Crisis (2014-present) increased awareness of the dangers of drinking lead-contaminated water. Elevated water. Elevated lead-contaminated drinking of dangers the of awareness increased (2014-present) Crisis Water Michigan Flint, The The majority of studies confirm the association between alpha-1 antitrypsin deficiency and juvenile idiopathic arthritis(JIA). arthritis(JIA). idiopathic juvenile and deficiency antitrypsin alpha-1 between association the confirm studies of majority The D I 1 T 1 , Ieva Saulite , Ieva I O 7 N Topics: Topics: 1 2 , Jeremy Blankenship , Jeremy Children University Hospital, Riga; [email protected] Riga; Hospital, University Children 1,2 Preterm Infant, Infant Development Infant Infant, Preterm Rare Diseases Ingrida Rumba-Rozenfelde , Ingrida CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 2 4 , Kanday Campbell , Kanday University of Michigan - Flint, School of nursing; [email protected] nursing; of School -Flint, Michigan of University 1,2

2 , Suzanne Cupal , Suzanne 3 University of Michigan - Flint, Department of public health and and health public of Department -Flint, Michigan of University POSTER SESSION 1 SESSION POSTER 3 , Laurel Hilliker , Laurel 2 , Marilyn Filter , Marilyn 4 85

Abstracts

86 15 10 Department of 2 MaximumAnkle Dorsiflexion in Swing 10 10 in Swing Clearance POSTER SESSION 1 0 0 Foot Stance Rotation in 0 0

Hind‐foot Varus/ Hind‐foot Valgus in Stance

1 14 20 Stance 2 Dorsiflexion in MaximumAnkle Yalova University, [email protected] Turkey; Yalova, 2 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE 20 10 , Hulya Nilgun Gurses Orthopaedics General Pediatrics, Allergy, Immunology & Pulmonology Heel , İsmail Reisli 2 Lift in After KT 10 10 14 0 0 10 10 0 0 10 After 14 KT 10 10 2 Stance Topics: Topics: 20 10 N 7 O I in Stance , Sevgi Keleş 1 T 1 I , Yilmaz Kutuk 1 D Initial Contact Initial Idiopathic toe walking (ITW) is a stubborn gait pathology with no known etiology that is characterized as premature heel-rise or Commonvariable immunodeficiency is a (CVID) primary immunodeficiency (PID) that typically presents with E

CVID is CVID heterogeneous a disease, and so diagnosis is frequently delayed. In patients, CVID pulmonary complications relate to This case report conducted to evaluate the acute effects of KT on m.tibialis anterior of the child with ITW. Our results showed that h t 9 20 The median age at disease onset was 6.4± 5.2 years, and the mean age ± 3.8 at diagnosis years. The delay was in 11.6 diagnosis The total score of foot section for of EVGS bilateral 5 steps PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: Before KT After KT Bezmialem Vakif University, Turkey; Pediatric Infectious Diseases, Department of Paediatrics, Selcuk University Faculty of Medicine, Konya-Turkey; ID: 299 15 / PO1: / PO1: 14 ID: / PO1: 159 Introduction: Introduction: hypogammaglobulinemia and impaired antibody production. It is one of the most frequently occurring disorders, PID after IgA deficiency and IMMUNODEFICIENCY Materials and Methods: The demographic, clinical, and laboratory characteristics children of 12 male, (seven five female) withCVID were Before KT 20 15 20 20 10 0 0 Deniz Tuncer Poster Presentation Poster Presentation to infections rather than non-infectious complication. The Ig G levels patients of 10 (83.3%) were low; those of another two patients were Results: transient hypogammaglobulinemia. transient Purpose: This study aims to promote awareness whose of CVID, clinical spectrum is quite broad. the child had an improvement in the score of foot section after of EVGS the application In the of KT. light of thisfinding, larger sample studies, found upon follow-up to have decreased. The number of B cells in patients CVID is variable. All patients received IVIG replacement therapy at functions of video player were used while evaluating the gait. steps 10 of 5 gait trials which corresponding to the exact middle of the walking for dominant and nondominant sides was noted before and after According KT. to the scores there of EVGS, was no heel contact before KT. 5 gait trials were video-recorded from frontal and sagittal plans minutes in 15 after KT application. Pausing and frame-by-frame monitoring 8:66.6%), and recurrent8:66.6%), gastroenteritiswas learned41.6%) (five cases;from the anamnesis collected at diagnosis. Growth retardationwas Pediatric Allergy and Immunology, Department of Paediatrics, Necmettin Erbakan University Meram Faculty of Medicine, Konya-Turkey; Recurrent lower respiratory tract infection (percentage recurrent 83.3%), with LRTI-10: upper respiratory infection (percentage with URI- EFFECT OF KINESIO TAPING® APPLICATION ON HEEL CONTACT IN A CASE WITH IDIOPATHIC TOE WALKING TOE CASE WITH IDIOPATHIC A IN CONTACT HEEL ON APPLICATION EFFECT OF KINESIO TAPING® EVALUATION OF CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF CHILDREN WITH COMMON VARIABLE OF CHILDREN WITH COMMON VARIABLE CHARACTERISTICS IMMUNOLOGICAL AND OF CLINICAL EVALUATION physicians to be aware of these manifestations, to assist in ameliorating diagnostic delays. Gülsüm Alkan Case Report: A 3 year-old girl with persistent toe walking, who was referred to the Department of Pediatric Physiotherapy Rehabilitation was Conclusion: Conclusion: Clearance in Swing Maximum Ankle Dorsiflexion in Swing was 5.1 ± 3.3 years.was Additionally, 5.1 in nine cases, of the 12 there was parental consanguinity. Overall, of patients 75% reported frequent infections. which display the effects of KT on gait in children with İTW, are needed. way wereway taken for right and left sides. The case was evaluated for only foot section, which consists 7 items score of Totally EVGS. steps of 10 no-heel contact. The aim of this case report is to examine the acute effects of Kinesio-taping® (KT) in a child with ITW. Initial Contact in Stance Heel Lift in Stance Maximum Ankle Dorsiflexion in Stance Hind‐footVarus/Valgus in Stance Foot Rotation in Stance significant decrease in URI yearsat 5 0.05). (p < 1 1 doses of 500 mg/kg every three weeks. There was a decrease in LRI and frequency AGE in the firstyear of IVIG treatment, and a statistically diagnosis delays, the age at onset of symptoms, and the prevalence of lung infection before treatment. In children, PIDs are life threatening, detected of patients, in 75% and bronchiectasis presented in four patients detected We (33.3%). autoimmune disease in five patients(41.6%). [email protected] examined Walking with Questionnaire Toe Tool Form and Video-Based Observational Gait Analysis. KT applied on m.tibialis anterior bilaterally. and so early diagnosis and the early initiation of treatment will help preclude complications. As a result, it is important for all specialist analyzed retrospectively. Patients were diagnosed in line with the diagnostic criteria of the European Society for Immunodeficiency Diseases. After KT application on m. tibialis anterior the child showed 4 times heel contact and 2 times flatfoot and 4 times toe contact in stance phase of All patients diagnosed with autoimmune diseases were over the Patients age of 10. with before CVID the years age of 10 are more susceptible Table 1: Table 10 steps.10 The difference between the scores ofbefore and after KT application The is shown score 1. in Table decreases as the steps improves.

Abstracts THE USINGOF ABDOMINAL REGIONAL SATURATION INPRETERMNEONATES WHENORGANIZINGENTERIC Tetiana Kurilina Tetiana 4061 ASQ filled in by parents and returned to pediatricians. Trained paediatricians reached a total of 5,500 children (25 Roma) having some some having Roma) (25 children 5,500 of total a reached paediatricians Trained pediatricians. to returned and parents by in filled ASQ 4061 average of 33%, 98% participants were satisfied. Instruments for ECD assessment (ASQ-3, IGMCD) were applied in more than 4000 children. children. 4000 than more in applied were IGMCD) (ASQ-3, assessment ECD for Instruments satisfied. were participants 98% 33%, of average effective way for increasing the quality of health care system to support ECD at the primary health care level. care health primary ECD the at support to system care health of quality the increasing way for effective gmail.com developmental play and positive interaction with children. At the national level, an elective course on ECD for medical students in 2 medical 2medical in students medical ECD for on course elective an level, national At the children. with interaction positive and play developmental gestational age. The human research ethics committees of the Institute approved the study, and informed parental consent was obtained for all all for obtained was consent parental informed and study, the approved Institute the of committees ethics research human The age. gestational organization of feeding under the NIRS data allowed to decrease the frequency of NEC development to one third in all groups. Besides that, a a that, Besides groups. all in third one to NEC development of frequency the decrease to allowed data NIRS the under feeding of organization of resources additional for asearch motivate neonates preterm for feeding enteric of order standardized of implementation the of despite decrease of data to 55 % was the reason for reduction of enteric strain (a pause in feeding or cut-off of increasing of capacity). Individual Individual capacity). of increasing of cut-off or feeding in (a pause strain enteric of reduction for reason the %was 55 to data of decrease 1 risks factors. Paediatricians’ filled check lists for monitoring the development of 1429 children. . Analysis of 1429 children (30% Roma) showed: showed: Roma) (30% of children 1429 Analysis . of children. 1429 development the monitoring for lists check filled Paediatricians’ factors. risks support of MoH and UNICEF, aimed at building the health care system for supporting ECD. The primary outcome and objective of this Project is is Project this of objective and outcome primary ECD. The supporting for system care health the building at UNICEF, and aimed MoH of support CARE INSERBIA stabile preterm neonates under 32 weeks of gestation in the dynamics of the formation of enteral nutrition. enteral of formation the of dynamics the in gestation of weeks 32 under neonates preterm stabile SI “Institute of Pediatrics, Obstetrics & Gynecology NAMS of Ukraine”, Ukraine; [email protected] Ukraine; Ukraine”, of NAMS &Gynecology Obstetrics Pediatrics, of SI “Institute regional abdominal saturation was 78±3,8 %, 71±4,2 %, 67±2,6 % corresponding in children 30-32 weeks, 28-29 weeks, 26-27 weeks. The The weeks. 26-27 weeks, 28-29 weeks, 30-32 children in 67±2,6 %corresponding %, 71±4,2 %, 78±3,8 was saturation abdominal regional SUPPORT EARLY CHILDHOODDEVELOPMENT(ECD)BY STRENGTHENINGTHECAPACITY OFPAEDIATRIC HEALTH monitoring the state of intestine and the evaluation of tolerance of feeding. of tolerance of evaluation the and intestine of state the monitoring ​Conclusion: when increasing the capacity of feeding. The duration of monitoring was no less than 6 hours (2-3 feeding). In the beginning of enteric feeding feeding enteric of beginning the In feeding). (2-3 6hours than less no was monitoring of duration The feeding. of capacity the increasing when which allows to provide individual program of enteric feeding in deep and extremely preterm neonates. preterm extremely and deep in feeding enteric of program individual provide to allows which Conclusion: play stimulation rose from 29% to 43%. About 50% of Roma parents improved their practices reducing identified risks for ECD, using adequate adequate ECD,for using risks identified reducing practices their improved parents Roma of 50% About 43%. to 29% from rose stimulation play partners. positive moment of the monitoring of abdominal oxygenation was the reduction of duration of transition into the total enteric feeding, especially especially feeding, enteric total the into transition of duration of reduction the was oxygenation abdominal of monitoring the of moment positive provided with the help of oxymeter INVOS 5100C with neonatal sensory devices. Children were divided into groups with the step of 2 weeks of of 2weeks of step the with groups into divided were Children devices. sensory neonatal 5100C INVOS with oxymeter of help the with provided ECD, including in-service training, introducing of standardized instruments for monitoring child development, and on-site support represent the the represent support on-site and development, child monitoring for instruments standardized of introducing training, in-service ECD, including FEEDING 59% had difficulties in any domain, 45% to 64% improved developmental outcomes after pediatric interventions; in Roma families, age specific specific age families, Roma in interventions; pediatric after outcomes developmental 64%improved 45%to domain, any in difficulties had 59% faculties (Belgrade, Novi Sad); ongoing process for improving education on ECD for postgraduate students in Pediatrics. in students postgraduate ECD for on education improving for process Sad); ongoing Novi (Belgrade, faculties Presentation Poster Results: of training and education sustainable for basis of Developing level: ECD. At national support to systems health local and national of creation the with implemented Serbia of Association Paediatric by (2013-2016), Project conducted long 3-year the of results main the To present Purpose: Presentation Poster Rudić Results: was monitoring The observed. were feeding enteric total the into transition of period the all during feeding of capacity the increasing the clinical in spectroscopy infrared near the with oxygenation abdominal regional of data of obtain the was research the of aim The Purpose: Dragana Lozanović Analyzing the data obtained by both Project and primary health care center (PHC) coordinator reports: tests of of tests reports: (PHC) coordinator center care health primary and Project both by obtained data the Analyzing Methods: and Materials 107 preterm neonates under 32 weeks of gestation with the monitoring of regional abdominal oxymetria when when oxymetria abdominal regional of monitoring the with gestation of weeks 32 under neonates 107 preterm Methods: and Materials increasing the quality of pediatric support to tham and their families. These results confirm that the investment in knowledge of pediatricians on on pediatricians of knowledge in investment the that confirm results These families. their and tham to support pediatric of quality the increasing instruments for screening and assessment of ECD and organizational changes in PHC for improving availability and quality of services. of quality and availability improving for PHC in changes organizational ECD of and assessment and screening for instruments (PAS) Serbia of and Association Pediatric the by out carried been have which projects, several through families, their and development, early in in Serbia; Serbia; in ID: 145 /PO1:ID: 17 health care professionals in the field of ECD. At local level: support of the quality of the PHC system in 9 municipalities using: training modules, modules, training using: municipalities in 9 system PHC the of quality the of support level: of ECD.local At field the in professionals care health Introduction: ID: 279 /PO1: 16 279 ID: Introduction: infants. There were no conflicts of interest for the authors. the for interest of conflicts no were There infants. in extremely preterm infants (under 28 weeks of GA). of weeks 28 (under infants preterm extremely in knowledge gained, satisfaction of courses participants, and activities in the implementation of knowledge gained at the educational courses. educational the at gained knowledge of implementation the in activities and participants, courses of satisfaction gained, knowledge Institute of Mothet and Child Health Care of Serbia “Dr Vukan Čupić”, Belgrade, Serbia; Serbia; Belgrade, Čupić”, Vukan “Dr Serbia of Care Health Child and Mothet of Institute PO1: POSTER PRESENTATIONS: 1 SESSION 4 , Veronika Išpanović , Veronika Training of 90 pediatricians in 9 municipalities was conducted through 11 basic courses. The level of knowledge increased by an an by increased knowledge of level The 11 courses. through basic conducted was 9municipalities in pediatricians 90 of Training The assessment of regional abdominal saturation started from the day of transition from the minimal trofic feeding and was continued continued was and feeding trofic minimal the from transition of day the from started saturation abdominal regional of assessment The 4 20 9 Institute of Mental Health of Belgrade; Belgrade; of Health Mental of Institute t h The improvement of ECD outcomes for children, increase of families actively applying early stimulation were achieved by by achieved were stimulation early applying actively families of increase children, for ECD of outcomes improvement The The monitoring of abdominal saturation may be a useful diagnostic method of detection of hypoxia/ischemia of the intestine, intestine, the of hypoxia/ischemia of detection of method diagnostic auseful be may saturation abdominal of monitoring The

E In the last 6 years, the cooperation of UNICEF and the Ministry of Health of Serbia (MoH), has been aimed at supporting children children supporting at aimed been has (MoH), Serbia of Health of Ministry the and UNICEF of cooperation the 6years, last the In High frequency of the food intolerance and development of necrotizing enterocolitis in deep and extremely preterm neonates neonates preterm extremely and deep in enterocolitis necrotizing of development and intolerance food the of frequency High D I T 1 I , Andrii Pysariev, Tetiana Znamenska Tetiana Pysariev, , Andrii O 7 N 1 , Radovan Bogdanović Topics: Topics: 5 , Stanislava Vučković , Stanislava Preterm Infant, NICU Infant, Preterm General Pediatrics, Infant Development Infant Pediatrics, General CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 2 , Jelena Zajeganović Jakovljević ,Zajeganović Jelena 5 Society for Child and Adolescents Psychiatry and Related Professions; dr.lozanovic@ Professions; Related and Psychiatry Adolescents and Child for Society 3

3 , Marica Milidrag Marica , POSTER SESSION 1 SESSION POSTER 2 Pediatric Association of Serbia; Serbia; of Association Pediatric 2 , Ljiljana Sokal Jovanović Sokal Ljiljana , 3 UNICEF Office Office UNICEF 2 , Nenad , Nenad 87

Abstracts 88 1,2 , Ahmed Alhammadi 1,2 POSTER SESSION 1 , Hatim Abdelrahman 1,2

, Muna Maarafiya 1 Weill cornell medical college; [email protected] 2 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE , Manasik kamil Hassan 1 General Pediatrics, Health Economics General Pediatrics, Management , Najla Ba Sharahil, Bassil Laghrouz, Ahmed El Makki, Amira Mustafa Topics: Topics: N 7 O I , Ahmed Essam 1 T 1 I D Self-assessment, self-directed learning(SDL)is one of the cornerstone for the new aura of teaching and learning . it had been Patient handover is a crucial process for transfer of patients’ information. The ultimate goal of handover is to ensure patients The majority of the residents’ handovers were inclusive of the 9 elements of SBAR. An extra important element was observed in E

Nearly all the residents in this study placed a high value on SDL and perceive it as beneficial for promote education and academic h t 9 20 Cross-sectional Survey included details of demographics and barriers to Self-Directed Leering use in clinical practice conducted An observational study was conducted in Pediatric Department of Hamad General Hospital. The observational tool was structured Out of 50 respondents,(31) juniors Seniors. and Nearly (19) perceived (90%) lifelonglearning as necessary to physician’s carrier. There were 26 endorsement observations collected from different types of endorsement (Junior to Junior, Senior to Junior, Junior to PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: Hamad medical corporation, Qatar; barriers related to their learning level, program level and external environments. allow residents to have protected time and resource for teach by the receiving team. Creating a modified handover modality in form of SBARR may greatly improve endorsement safety and quality. Introduction: / PO1: 18 ID: 104 / PO1: Introduction: handovers such as: organization of the whole process of handover, insure presence of protected time, standard systems and training for all in (ILP (16%), maintainingin residency (ILP (16%), training Lack requirements of support (16%), from residency program (13%) handover between morning team and the on call team . It included the organization of the handover, 9 essential elements conveyed in SBAR identify frequent missing elements in the residents study handover. the To organization of the whole handover process. / PO1: 19 ID: 103 / PO1: in endorsement. The commonest missing elements were patients’ demographics and location followed (23%) by situation awareness (19%). improvement in SBAR content. Adding “read back by receiver” to the= (R) SBAR may ensure that crucial patients’ information is well understood Methods: Major barrier identified were; Lack of balance between social life and clinical workload Insufficient(20%), understanding of how to construct an Methods: Manasik kamil Hassan Purpose: identify To barriers to use SDL among pediatrics residents. explore potential To recommendations that can overcome challenges. To Khaled Siddiq Khaled Hamad medical corporation, Qatar; [email protected] Results: the residents in their training will improve theirown professional development; challenges toward implantingin the (SDL) training program Poster Presentation there is an area of improvement for the patients’ information handover. Purpose: study the To completion of patient information during handover using SBAR modality at the time of residents endorsement. To Results: to examine the contents of the oral handover using SBAR method, which was filled by chief residents. the observationwas done at the time of Poster Presentation from July -November among 2016 pediatrics residents at Hamad Medical Corporation main tertiary teaching hospital in Qatar.it include details to Junior, Junior 19.2% Junior to Junior, to Senior; 15.4% while Senior to Fellow, Fellow to Fellow, and undescribed had 3.8% each. 50% of the residents’ handovers had completed 100% the 9 elements of endorsement using SBAR,while 35% covered of the 75% SBAR element format and flow of the endorsement throughout different team levels. PROGRAM DOHA,QATAR PROGRAM; THE RESIDENTS PERSPECTIVE PROGRAM; THE RESIDENTS Questions offered objective answers utilizing 3-point Likert scale program faculties and directors. Organization of the whole handover process was 38% of more than 4 that is very good which and only of 1, is 12% poor organization. Considered as one to support way transition from undergraduate to postgraduate Learning. using the skills of self-directed learning by (SDL) Conclusion: will create gap between residents and efficient training,thus better understanding of those challenges will ensure earlier intervention by the Conclusions: SDL, implement Hands-on workshop in their curriculum, use frameworks support on-going learning; regular meet with advisor to discuss ILPs Senior, Senior to Senior, Senior to Fellow, and Fellow to Fellow). 30.8% of the endorsement comes from from Senior Senior to Senior, 23.1% safety, thus, its standardization enables concise relay of information across team members. Many factors is contributing to efficient and safe staff. Different systems of communication have been developed to achieve effective and safe handover such as SBAR however and still IPASS, CURRENT PRACTICE OF VERBAL HANDOVER USING SBAR MODALITY AMONG PEDIATRIC RESIDENTS IN ACGME-I RESIDENTS IN AMONG PEDIATRIC HANDOVER USING SBAR MODALITY CURRENT PRACTICE OF VERBAL CHALLENGES TOWARDS USE OF SELF-DIRECTED LEARNING IN ACGMEI MULTI CULTURAL PEDIATRIC RESIDENCY PEDIATRIC CULTURAL ACGMEI MULTI IN USE OF SELF-DIRECTED LEARNING CHALLENGES TOWARDS 1 of demographic, perception and attitude toward self-directed learning and challenges that might prevent effective SDL among residents. explore ideas to ward effective creation of individual learning plan and life long learning among residents. effective Individual Lack learning of time to plan create (18%), plan for and (ILP) of monitoring to apply it (17%),Lack (qualified teacher/ adviser) advancement. Our study shed light on the barriers limiting use SDL in ACGMEI multi-cultural program. Residents in training identified several and evaluate process can overcome these obstacles. 12% of the12% endorsements, which is “read back by the receiver”; an element not part of the SBAR modality. The study was highlighted areas for

Abstracts The incidence of clinically detected fat embolism (which occurs in <1%) differs from the incidence found in post mortem examination (20%). In rare (20%). rare In examination mortem post in found incidence the from <1%) in differs occurs (which embolism fat detected clinically of incidence The THE EFFECTOFMATERNAL AGE ONPREGNANCY OUTCOMEINCYPRUS ataxia was negative. At 4 years of age, besides ataxia, choreoathetosis was noticed, which, in association with previous diagnosis of HC and and HC of diagnosis previous with association in which, noticed, was choreoathetosis ataxia, besides age, of At 4years negative. was ataxia analytical and vital parameters as well as neurological state and was discharged after four days. four after discharged was and state neurological as well as parameters vital and analytical of normalization with improvement clinical agradual had He unit. care intermediate an to transferred then was patient The embolism. adipose and low birth weight. The older the mother on the day of the delivery, regardless of demographic, social and economic status, significantly significantly status, economic and social demographic, of regardless delivery, the of day the on mother the older The weight. birth low and analysis was performed using the statistical package IBM SPSS 21.0. SPSS IBM package statistical the using performed was analysis population. Cypriot among and petechiae. The clinical symptoms usually develop within the first 12 to 72 hours postoperative and the respiratory system is usually the first to first the usually is system respiratory the and postoperative hours 72 to 12 first the within develop usually symptoms clinical The petechiae. and exon 3. She began treatment with tetrabenazine with improvement of coreoatetosis. Pulmonary disease was excluded and she was referred to to referred was she and excluded was disease Pulmonary coreoatetosis. of improvement with tetrabenazine with treatment began She 3. exon global developmental impairment, led to the molecular study of the NKX2-1 gene. It was identified a pathogenic mutation in heterozygosity in in heterozygosity in mutation pathogenic a identified was It gene. NKX2-1 the of study molecular the to led impairment, developmental global of 10,9 seconds) and an international normalized ratio of 1,45. Considering the clinical and analytical alterations, the diagnosis hypotheses hypotheses diagnosis the alterations, analytical and clinical the 1,45. of Considering ratio normalized international an and 10,9of seconds) of periods presented he day postoperative first the On uneventful. was which correction, surgical to admitted was He shaft. femoral the of correlated with increased incidence of preterm delivery (p<0.001) and of a newborn with low birth weight (p<0.001). weight birth low with anewborn of and (p<0.001) delivery preterm of incidence increased with correlated cases, this condition evolves into a fat embolism syndrome, which is characterized by the triad: respiratory failure, altered state of consciousness consciousness of state altered failure, respiratory triad: the by characterized is which syndrome, embolism afat into evolves condition this cases, diagnosis. The main focus consists in an effective preventive management. preventive effective an in consists focus main The diagnosis. 1 saturations of 89% with a fiO2 0,21 and a diastolic blood pressure in the percentile 5 for his age. Cerebral computed tomography (CT) showed showed (CT) tomography computed Cerebral age. his for 5 percentile the in pressure blood diastolic a and 0,21 afiO2 with 89% of saturations CONGENITAL HYPOTHYROIDISM AND BRAIN-LUNG-THYROIDSYNDROME resonance imaging showed images suggestive of Chiari malformation type I. She maintained normal thyroid function and the genetic panel for for panel genetic the and function thyroid normal maintained She I. type malformation Chiari of suggestive images showed imaging resonance magnetic Brain respectively. age, of 2years and 12 at months noticed were ataxia and Hypotonia hypoplasia. thyroid showed Ultrasound no signs of fracture or acute blood collections. Arterial blood gas analysis revealed hypoxemia (pO2: 59 mmHg). The analytical study showed showed study analytical mmHg). The 59 (pO2: hypoxemia revealed analysis gas blood Arterial collections. blood acute or fracture of signs no maintained He bases. both on crepitations rare had he auscultation pulmonary In chest. upper anterior the in rash apetechial and membranes death. of cause lead the being failure heart right acute with reserved, is form fulminant the of prognosis The necessary. were fat embolism and pulmonary thromboembolism. CT scan of the chest with contrast was performed confirming the diagnosis of peripheral peripheral of diagnosis the confirming performed was contrast with chest the of CTscan thromboembolism. pulmonary and embolism fat were weeks) (cohort group) and 349 women who carried their pregnancy to term (>37 weeks) (control group). The aim was to collect data relating relating data collect to was aim group). The (control weeks) (>37 term to pregnancy their carried who women 349 and group) (cohort weeks) (<37 prematurely birth gave who women 348 to administered were Questionnaires hospital. astate or aprivate either in birth gave who women literature. international the in known well is grams) (<2500 newborn the of weight birth low and gestation) of weeks Five-year-old girl, the first daughter of non-consanguineous parents. Term pregnancy and childbirth without complications. complications. without childbirth and pregnancy parents. Term non-consanguineous of daughter first the girl, Five-year-old report: Case Fontoura Manuel Castro-Correia, Conclusion: fracture a confirmed x-ray The limb. lower right the of trauma to due department emergency the to presents male, A15-year-old report: Case Liz de Ferraz Catarina Congenital hypothyroidism was detected in the neonatal screening of metabolic diseases and levothyroxine was started at 8 days of age. age. of 8days at started was levothyroxine and diseases metabolic of screening neonatal the in detected was hypothyroidism Congenital [email protected] Portugal; João, São de Hospitalar Centro Centro Hospitalar Tâmega e Sousa, Portugal; [email protected] Portugal; eSousa, Tâmega Hospitalar Centro prostration and altered state of consciousness. On physical examination he had a slow but oriented speech, cutaneous pallor, dry mucous mucous dry pallor, cutaneous speech, oriented but aslow had he examination physical On consciousness. of state altered and prostration FAT EMBOLISMSYNDROME– A CLINICAL CASE Presentation Poster phenotype. CAHTP the of expression the in included be may patient this evolution. clinical favorable with intervention, early for team local the thrombocytopenia (127 000 mcg/L) with D-Dimers elevation (812 ng/mL). He presented a prolonged protrombine time (16 seconds to a normal anormal to (16 time seconds protrombine aprolonged (812 presented He elevation ng/mL). D-Dimers with (127 mcg/L) 000 thrombocytopenia Results: statistical The mother. the of profile social and economic demographic, the as well as weight birth newborn’s the and age gestational the to newborn, the of weight birth low and birth (preterm) premature of incidence the on age mother’s the of effect the To investigate Purpose: Paraskevi Stylianou-Riga Paraskevi Presentation Poster Presentation Poster Discussion: NKX2-1 gene on chromosome 14q13. chromosome on gene NKX2-1 Sofia Helena Ferreira Helena Sofia Multidisciplinary follow-up was crucial for the diagnosis of CAHTP, allowing preconception counselling. The Chiari malformation type I found in in Ifound type malformation Chiari The counselling. CAHTP, of preconception allowing diagnosis the for crucial was follow-up Multidisciplinary This article describes a prospective study carried out in Cyprus from March 2015 to April 2016. The participants were were 2016. participants 2015 The April to March from Cyprus in out carried study aprospective describes article This Method: and Material ID: 252 /PO1: 252 21 ID: Introduction: ID: 281 /PO1: 281 20 ID: Introduction: ID: 200 /PO1: 22 200 ID: Introduction: be affected. The diagnosis is clinical and the treatment is based on supportive care. In severe cases, admission to an intensive care unit may be be may unit care intensive an to admission cases, severe In care. supportive on based is treatment the and clinical is diagnosis The affected. be the in mutation heterozygous by caused is It chorea. hereditary benign and syndrome distress (CH), respiratory hypothyroidism congenital by Neonatal Intensive Care Unit, “Archibishop Makarios III Hospital”; Hospital”; III Makarios “Archibishop Unit, Care Intensive Neonatal PO1: POSTER PRESENTATIONS: 1 SESSION Results indicate a statistically significant correlation (p<0.001) between the age of the mother on the day of delivery, premature birth birth premature delivery, dayof the on mother the of age the between (p<0.001) correlation significant astatistically indicate Results 20 9 t h We should suspect of a deficiency in NKX2-1 when HC is associated with neurological and/or respiratory disease. disease. respiratory and/or neurological with associated is HC when NKX2-1 in adeficiency of suspect We should Fat embolism syndrome is a rare complication in paediatric patients and a high index of suspicion is essential for its early early its for essential is suspicion of index ahigh and patients paediatric in complication arare is syndrome Fat embolism

E Fat embolism is a condition often under diagnosed, mostly associated with surgical procedures in traumatic long bone fractures. fractures. bone long traumatic in procedures surgical with associated mostly diagnosed, under often acondition is Fat embolism The effect of maternal age (<18 and >35) on pregnancy outcome and more specifically on the incidence of preterm birth (<37 (<37 birth preterm of incidence the on specifically more and outcome pregnancy on (<18 age >35) and maternal of effect The Choreoathetosis and congenital hypothyroidism with or without pulmonary dysfunction is a rare condition and it is characterized characterized is it and condition arare is dysfunction pulmonary without or with hypothyroidism congenital and Choreoathetosis D I T 1 I O 7 N , Sandra Pereia, Sylvia Jacob, Mariana Abreu, Daniel Gonçalves, Mafalda Sampaio, Miguel Leão, CíntiaLeão, Miguel Sampaio, Mafalda Gonçalves, Daniel Abreu, MarianaSylviaJacob, Pereia, Sandra , , Nuno Ferreira, Joaquim Cunha, Ângela Machado Ângela Cunha, Joaquim Ferreira, , Nuno Topics: Topics: Topics: 1 , Petros Galanis , Petros Orthopaedics, Injuries &Trauma Injuries Orthopaedics, Endocrinology &Growth Endocrinology Preterm Infant, NICU Infant, Preterm CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 2 , Angelos Rigas , Angelos 3 , Thalia Papadouri , Thalia 2 Open University of Cyprus; Cyprus; of University Open

1 , Mamas Theodorou , Mamas POSTER SESSION 1 SESSION POSTER 3 Apollonion Hospital;Apollonion [email protected] 2 89

Abstracts 1 90 , Vasiliki Drosou 3 Laboratory of Forensic Medicine and 2 , Georgios Theodoridis Georgios , 2 POSTER SESSION 1 , Helen G Gika 1 School of Chemistry, Aristotle University of Thessaloniki, 3

, Vasiliki Soubasi Vasiliki , 1 , Kosmas Sarafidis 2 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE General Pediatrics, Allergy, Immunology & Pulmonology NICU Preterm Infant, NICU , Olga Begou Topics: Topics: 1 Topics: N , Tamara Kosenkova, Natalia Bogdanova 7 O I 1 , Lokesh Tiwari T I D Congenital idiopathic pleural effusion is a rare condition with an incidence of about 1 in 12000 to 1 in 15000 pregnancies. It can The state of environment and ambient air has considerable influence on the formation and course of diseases of respiratory Brain injury is a leading cause of perinatal mortality and long-term neurological disability in neonates. In term infants, most E

Congenital idiopathic pleural effusion is a rare entity in a newborn, which can be resolved spontanously without intervention The above mentioned results are inline with the results of similar surveys in other countries and document that, compared to Urine metabolomics has the potential to early identify neonates at high-risk for adverse neurological outcome, which constitutes a h t 9 20 40 preterm neonates neonates with (15 encephalopathy of prematurity and 25 controls) as well as 33 with term moderate/ ones (13 PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: 1st Department1st of Neonatology, School of Medicine, Aristotle University of Thessaloniki, Greece; be severe enough to cause significant respiratory distress. Here in, we report a case of isolated idiopathic pleural effusion, which resolved both preterm and term infants developing brain damage is to a great extent unpredictable. Therefore, early identification and prognostication Introduction: ID: 25 261 / PO1: Introduction: / PO1: 24 ID: / PO1: 144 Introduction: / PO1: 23ID: 183 / PO1: Materials and Methods: Preterm neonates(<32 weeks gestational with age) encephalopathy of prematurity and term ones suffering HIE Nikolaos G. Efstathiou G. Nikolaos Sunaina Arora Sunaina National Medical Research Almazov VA Russian Center. Ministry of Health, St. Petersburg, Russia, Russian Federation; [email protected] Poster Presentation Poster Presentation Results: Purpose: aimed We to define urine metabolomic profiles in encephalopathic preterm and term neonates and identify early diagnostic and Poster Presentation Elena Turganova FEATURES OF THE SPECTRUM OF SENSITIZATION IN CHILDREN WITH ASTHMA LIVING IN A LARGE INDUSTRIAL CITY LARGE INDUSTRIAL A LIVING IN ASTHMA IN CHILDREN WITH OF THE SPECTRUM OF SENSITIZATION FEATURES periventricular leukomalacia are the major forms of brain damage in preterm ones. Nowadays, management is largely supportive, with the valuable informationto the bedside clinician. prognostic biomarkers of brain injury. pleural effusion. Echo done showed mild pericardial effusion with of about a VSD 2.5 mm with left to right shunt. Baby did not develop respiratory Conclusion: Conclusion: was to examine the relationship between ambient air pollutants and the characteristics of the spectrum of sensitization in children with asthma were observed at the sampling time points. Urine metabolomics was possible to predict unfavorable neonatal outcomes. Conclusion: were collected 3 and on 9 of life days 1, for metabolomic analysis using liquid chromatography-tandem mass spectrometry. Data related to Case Report: A full term baby girl delivered to a 26-year-old primigravida mother by normal vaginal delivery. Antenatal USG revealed complete younger women, older women in Cyprus are at increased risk of giving birth prematurely and to newborns with low birth weight. was normal and pericardial effusion resolved in 48 hours. As there were no dysmorphic features, karyotype was not done. As pleural effusion was ST STEPHEN HOSPITAL, DELHI; [email protected] HOSPITAL, STEPHEN ST running processes of allergic inflammation,hyper secretion, or maintaining, both at the cellular and humeral level. The purpose of this study Greece; [email protected] Greece; minimal and not resulted in respiratory distress, and resolved spontaneously, diagnostic tap was not done. No other fluid compartmentwas involved, negative and antibiotics were stopped baby on 3rd was shifted day, to mother and discharged on day 5 of life and is doing well till one month of age. spontaneouslywithout intervention. system, especially bronchial asthma. The most significant contribution to air pollution in the city makevehicle emissions containing nitrogen severe with HIE, 10 mild HIE controls) and 10 were evaluated. Metabolomic profiling documented separation between preterm neonates with CONGENITAL IDIOPATHIC PLEURAL EFFUSION RESOLVING SPONTANEOUSLY IN A NEWBORN A IN SPONTANEOUSLY EFFUSION RESOLVING PLEURAL IDIOPATHIC CONGENITAL URINE METABOLOMIC PROFILING IN NEONATAL BRAIN INJURY PROFILING IN NEONATAL URINE METABOLOMIC so hydrops was ruled out. USG cranium was normal. Baby’s CMV IgM was negative . Cord TSH and TSH on day 3 was normal. Sepsis screen was 1 demographic-clinical characteristics, brain injury and outcomes were also recoded. oxide, hydrocarbons, volatile organic compounds. Each of the pollutants affects the respiratory tract of the child, playing a decisive role in either of moderate severity residing in different districts of the metropolis. of neonates at risk for braindamage is of great clinical value. Metabolomics could contribute in this end, providing evidence on the metabolic often this is due to perinatal asphyxia and subsequent hypoxic-ischemic encephalopathy (HIE) whereas intraventricular hemorrhage and delivery. Mother was hypothyroid and was started on eltroxin from 2nd trimester, Mothers CMV IgG was positive. After birth baby cried immediately, distress during nursery She stay. was started on feeds at 2 hrs. of life, which she accepted well. Chest X ray and USG chest was repeated which collapse of left lung with pleural effusion and left sided renal pelvis dilatation. There was a lot of parental and obstetrician anxiety regarding the finding. encephalopathy vs.preterm controls, as well as between term infants with moderate/severe HIE and respective controls. Significant differences exception of therapeutic hypothermia, which nonetheless isapplicable only in term infants during the first 6 hours of life. Moreover, outcome in as well as preterm and term neonates without brain injury were prospectively studied during Urine a 2-year period samples (2014-2016). alternations in neonatal brain injury possibly associated with clinical manifestations, survival and long-term neurological outcome. antibiotics prophylactically. Blood gas analysis was normal. Chest X ray done revealed left sided haziness. USG chest done revealed left sided minimal Apgar scores was 9 at 1 and 9, 5 minutes. Baby shifted to nursery for observation. Sepsis screen was sent and she was started on intra venous The paediatrician and paediatric surgeon were well informed about the case and all the necessary equipmentfor resuscitation was arranged prior to Toxicology, SchoolToxicology, of Medicine, Aristotle University of Thessaloniki,Greece;

Abstracts The diagnosis of GDK demands a multidisciplinary and dietetic approach to prevent metabolic decompensation during illness or fasting, fasting, or illness during decompensation metabolic prevent to approach dietetic and amultidisciplinary demands GDK of diagnosis The Andreia Andreia Ribeiro assessment was normal, as well as ophthalmologic and hearing evaluation. He was referred to early childhood intervention services and started started and services intervention childhood early to referred was He evaluation. hearing and ophthalmologic as well as normal, was assessment according to Papille classification for haemorrhagic changes and Pidcock classification for ischemic changes. The neurological examination examination neurological The changes. ischemic for classification Pidcock and changes haemorrhagic for classification Papille to according (317 mg/dL) with normal creatine kinase, cholesterol, serum electrolytes, liver and thyroid function. Urine organic acid analysis revealed a high urine urine ahigh revealed analysis acid organic Urine function. thyroid and liver electrolytes, serum cholesterol, kinase, creatine (317 normal with mg/dL) ocular poor textures, food new to aversion with peculiarities sensorial babbling, (monotonous noted were features autistic months (24 At 33 months). environmentally disadvantaged district) the children were divided into 2 groups. In each district the most significant air pollutants were detected. In all all In detected. were pollutants air significant most the district each In 2groups. into divided were children the district) disadvantaged environmentally glycerol level and GKD was confirmed by genetic identification of GK gene mutation. He started a carbohydrate-reinforced diet and maintained autism- maintained and diet carbohydrate-reinforced a started He mutation. gene GK of identification genetic by confirmed was GKD and level glycerol hypertriglyceridemia showed chemistry Blood spectroscopy. with imaging resonance magnetic brain and analysis microarray hybridization genomic occupational therapy with sensorial integration, speech therapy for oromotor development. Complementary exams revealed normal comparative comparative normal revealed exams Complementary development. oromotor for therapy speech integration, sensorial with therapy occupational Growth features. dysmorphic no and age for hiperlaxity and hypotonia significant revealed examination Physical interaction). reciprocal and contact groups of allergens have been observed in patients aged 6-7 years (41%). 6-7 years aged patients in observed been have allergens of groups directed intervention. Slow progressive improvement was noted. So far, no metabolic crises or clinical hypoglycaemic episodes were registered. were episodes hypoglycaemic clinical or crises far, So metabolic no noted. was improvement progressive Slow intervention. directed developmental psychomotor His alone. feeding with corrected life, of days two first the in episodes hypoglycaemic had newborn the and diabetes, gradus I according to Papille had normal neurological examination at the age of 6 and 12 6and of months. age the at examination neurological normal had Papille to I according gradus child suffering bronchial asthma. bronchial suffering child combination with sensitization to other groups of allergens (epidermal, household, food). The greatest number of children with sensitization to 4 4 to sensitization with children of number greatest The food). household, (epidermal, allergens of groups other to sensitization with combination total of values higher significantly had regions unfavorable ecologically from however, patients sensitization, polyvalent by characterized determined in the first year of life with increasing severity of household sensitization with age. Pollen sensitization has also been detected detected been also has sensitization Pollen age. with sensitization household of severity increasing with life of year first the in determined differential diagnosis of global development delay in the presence of key biochemical markers, such as lipid or muscular enzyme abnormalities. abnormalities. enzyme muscular or lipid as such markers, key of biochemical presence the in delay development global of diagnosis differential due to loss of function of glycerol kinase enzyme which catalyses the phosphorylation of dietary glycerol to glycerol-3-phosphate, necessary necessary glycerol-3-phosphate, to glycerol dietary of phosphorylation the catalyses which enzyme kinase glycerol of function of loss to due 1 stages were remarkable for delayed cephalic control (5 months), sitting alone (9 months), first words (20 months) and autonomous, yet instable gait gait instable yet autonomous, and months) (20 words (9 first months), alone (5 sitting months), control cephalic delayed for remarkable were stages subclinical episodes of hypoglycaemia are a proposed mechanism. aproposed are hypoglycaemia of episodes subclinical risk for neurodevelopmental disorder in preterm newborns. Brain ultrasound is very useful in secondary health care because provides provides because care health secondary in useful very is ultrasound Brain newborns. preterm in disorder neurodevelopmental for risk hydrocephalus. as such complication their and hemorrhage intraventricular leukomalacia, periventricular as such IgE and more expressed degree of sensitization to the cause-significant allergens. Sensitization to household allergens (house dust) were were dust) (house allergens household to Sensitization allergens. cause-significant the to sensitization of degree expressed more and IgE General Hospital Prilep, Macedonia, Former Yugoslav Republic of; [email protected] Republic Yugoslav Former Macedonia, Prilep, Hospital General metabolic crisis, mental retardation and/or dysmorphic features, to asymptomatic adult pseudohypertriglyceridaemia. adult asymptomatic to features, dysmorphic and/or retardation mental crisis, metabolic GLYCEROL KINASEDEFICIENCY – A METABOLIC CAUSEOFGLOBAL DEVELOPMENTAL DELAY. We present an eighteen months-old boy, referred to neurodevelopmental outpatient department by developmental delay. He was the the was delay. He developmental by department outpatient neurodevelopmental to boy, referred months-old eighteen an We present Report: Case Conclusion: Conclusion: 12 6and of months. age the at done was interpreted were findings The findings. initial to according performed were examinations ultrasound Next life. of day third the at done was Conclusion: Gabriela Tavchioska Gabriela promote development and provide genetic counselling to families. The pathogenesis of psychomotor retardation in GKD is not yet clear, but but clear, yet not is GKD in retardation psychomotor of pathogenesis The families. to counselling genetic provide and development promote BRAIN ULTRASOUND AS A PROGNOSTICTOOL FORNEURODEVELOPMENTAL OUTCOMEINPRETERMNEWBORNS PV-IVH gradus I, and 2 premature newborns had normal brain ultrasound. 97% of newborn with normal initial brain ultrasound or with PV-IVH PV-IVH with or ultrasound brain initial normal with newborn of 97% ultrasound. brain normal had newborns 2premature and I, gradus PV-IVH Portugal; [email protected] first son of a 38 years old mother and a young father, non-consanguineous. No other relevant family history. Gestation was complicated by gestational gestational by complicated was Gestation history. family relevant other No non-consanguineous. father, young a and mother old 38 years of a son first the examined children was studied the level of total and specific IgE to five groups of allergens (food, household, pollen, epidermal and fungal). and epidermal pollen, household, (food, allergens of groups five to IgE specific and total of level the studied was children examined the Presentation Poster Results: Presentation Poster Results: initially ultrasound Brain study. the in included were and weeks 31 36 to from age gestational had newborns preterm of 39 37weeks. full the secondary in outcome neurodevelopmental their for newborns preterm in findings ultrasound brain of value prognostic present to Purpose: Helena Santos Helena or safe (environmentally residence of place on years). Depending 114 –5,33±0,27 age (mean included children study The Methods: and Materials This single center study is prospective with observational design. Out of 978 newborns, 56 (5.7%) were born before before (5.7%) 56 born were newborns, 978 of Out design. observational with prospective is study center single This methods: and Materials important both for the diagnosis of the disease, and for development of elimination activities to reduce the antigenic load on the organism of the the of organism the on load antigenic the reduce to activities elimination of development for and disease, the of diagnosis the for both important in children in the first years of life, but there were, as a rule, in the form of having sIgE to the pollen of trees only, while not in isolation but in in but isolation in not only,while trees of pollen the to sIgE having of form the in rule, as a were, there but life, of years first the in children in information for both pediatricians and parents. and pediatricians both for information prematurity with associated conditions brain for screen to used are waves sound high-frequency newborns preterm In infants. and newborns in in lipids synthesis. Its phenotype is remarkably variable with clinical and biochemical presentations varying from a life-threatening childhood childhood alife-threatening from varying presentations biochemical and clinical with variable remarkably is phenotype Its synthesis. lipids in ID: 186 /PO1: 186 ID: 26 ID: 180 /PO1: 180 ID: 27 facility. care health Introduction: Introduction: Hospital Center of Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal; Portugal; Gaia, de Nova Vila Gaia/Espinho, de Nova Vila of Center Hospital PO1: POSTER PRESENTATIONS: 1 SESSION It is established that the most important pollutant in the industrial city was nitrogen dioxide. Explored children of both groups were were groups both of children Explored dioxide. nitrogen was city industrial the in pollutant important most the that established is It Out of 39 premature newborns, 2 had PV-IVH gradus III and one of them consequent hydrocephalus, 17 had PV-IVH gradus II, 18 had 18 II, 17 had gradus PV-IVH had hydrocephalus, consequent them of one and III gradus PV-IVH 2had newborns, premature 39 of Out 20 9 t h Studying the spectrum and severity of sensitization in children living in ecologically unfavorable areas of the industrial city, is is city, industrial the of areas unfavorable ecologically in living children in sensitization of severity and spectrum the Studying The results of this moderate but locally important study have clinical relevance. Normal ultrasound confidently predicts reduced reduced predicts confidently ultrasound Normal relevance. clinical have study important locally but moderate this of results The Despite normal comprehensive metabolic neonatal screening, inborn errors of metabolism should be considered in the the in considered be should metabolism of errors inborn screening, neonatal metabolic comprehensive normal Despite

E Brain ultrasound as a non-invasive, safe and not expensive tool can provide in real-time useful information about the brain tissue tissue brain the about information useful real-time in provide can tool expensive not and safe anon-invasive, as ultrasound Brain Glycerol kinase deficiency (GKD) is a rare X-linked recessive disorder characterised by hyperglycerolaemia and glyceroluria, glyceroluria, and by hyperglycerolaemia characterised disorder recessive rare is a X-linked (GKD) deficiency kinase Glycerol D I T 1 1 I 1 O 7 , Maria Adriana Rangel Adriana Maria , N Topics: Topics: Preterm Infant, Infant Development Infant Infant, Preterm Gastroenterology & Metabolism, Infant Development Infant &Metabolism, Gastroenterology CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 1 , Cátia Leitão 1 , Isabel Pereira , Isabel

1 , Ana Vieira , Ana 2 National Health Institute Doutor Ricardo Jorge, Porto, Porto, Jorge, Ricardo Doutor Institute Health National POSTER SESSION 1 SESSION POSTER 1 , Sara Melo Sara , 1 , Carla Valongo Carla , 2 , Armanda Passas 91 1 ,

Abstracts 92 0.871 0.262 0.306 1.000 0.006* 0.025* 0.045* 0.001* <0.001* P-value School of Medicine, 2 7.7 7.7 23.1 46.2 69.2 15.4 15.4 15.4 92.3 76.9 92.3 30.8 30.8 53.8 % 100.0

1 1 7 2 2 2 4 4 9 3 6 N 13-18 (n=13) 12 12 13 10

2.8 5.6 11.1 11.1 11.1 11.1 91.7 41.7 16.7 47.2 94.4 44.4 88.9 58.3 27.8 58.3 83.3 % POSTER SESSION 1 0.057 0.614 0.863 1.000 0.007* P-value 1 2 4 4 6 7-12 (n=36) 21 21 17 N 32 15 34 33 16 10 30 Age 6.91 1.45 10.49 SD 183.77 9.1 9.1 0.0 0.0 54.5 18.2 18.2 54.5 54.5 36.4 36.4 90.9 90.9 81.8 63.6

10584.29 4,5 %

Yes 9.75 4-6 (n=11) 1 1 7 2 2 4 4 9 6 6 6 0 0 11.21 11.21 16.27 N 10 10 356.00 Mean 21038.10 0.0 0.0 0.0 0.0 0.0 0.0 11 21 21 21 16.7 16.7 66.7 16.7 N 33.3 83.3 33.3 20 % , Han-Ping Wu 100.0 100.0 3 Laboratory of Epidemiology and Biostastics, Changhua Christian Hospital, 1 1 1 0-3 (n=6) 5 2 2 4 6 6 0 0 0 0 0 0 3 N 2.81 4.54 11.81 11.81 SD 174.17 6.1 6.1 9.1 8710.51 59.1 22.7 21.2 54.5 45.5 68.2 37.9 90.9 93.9 78.8 25.8 31.8 % Renal or liver abscesses 4 4 6 21 17 N 25 52 62 15 45 14 39 36 30 60 8.66 No , Yu-Jun Chang Total (n=66) Total 11.98 11.98 16.93 1,2 363.86 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE Mean 16553.56 Emergency Pediatrics Emergency 45 45 44 44 19 N Topics: Male Liver abscess Female Periappendical Pelvic abscess Renal abscess Ward Intraperitoneal ICU abscess abscess Yes Yes Yes Yes Yes Yes Division of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital, Taiwan Taoyuan, 4 N /L) 9 , Wen-Chieh Yang 7 O I 1 T 1,2 I D Intra-abdominal abscesses generally form following the entry of enteric microorganisms into the peritoneal cavity through E

h t /L) 9 20 9 During the 8-year study period, a total of 66 patients (30 males and years; 36 females; range, mean 6 months age, 9.27±4.16 to 18 Comparison of laboratory tests of patients with intra-abdominal abscesses based on location Demographics and clinical presentations of the patients withintra-abdominal abscesses College of Medicine, Chang Gung University, [email protected] Taiwan; Taoyuan, PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: 5 Location of abscesses Diarrhea Fever Flank pain Signs of peritonitis Gender BUN (mg/dl) Hb (mg/dl) Platelet count (× 10 WBC (× 10 CRP (mg/L) CRP Abdominal pain Admission unit Anorexia or vomiting laboratory tests Department of Pediatric Emergency Medicine, Changhua Christian Children’s Hospital, Changhua, Taiwan; blood cell (WBC) counts, hemoglobin platelet (Hb), counts, blood urea nitrogen creatinine (BUN), reactive C - (Cr), protein levels.], (CRP) Introduction: / PO1: 28 / PO1: ID: 131 in the adolescent group than The other mean age serum groups 1). (Table WBC < 0.001) counts (P of all patients ± 9,500.53/μL were 17,980.45 intra-abdominal abscesses may include chillness, fever, nausea and vomiting, flank pain, abdominal pain, ileus, signs of peritonitis, raised immediately. Early diagnosis is imperative to minimize the potential for prolong admission and life-threatening complications. Materials and Methods: This study collected retrospectively pediatric patients aged years or 18 younger who presented to the with ED a Kaohsiung Medical University, Kaohsiung, Taiwan; Results: Purpose: In this study, we aim to analyze the clinical spectrum of intra-abdominal abscesses in patients who presented to the pediatric and ED, Poster Presentation from January 2004 The to following December information 2011. was obtained from the medical records of each patient: age, gender, clinical DEPARTMENT patients were treated with broad-spectrum intravenous cases antibiotics had a combination (16.7%) alone; 11 of broad-spectrum intravenous Changhua, Taiwan; Chun-Yu ChenChun-Yu years old) who presented to the with ED intra-abdominal abscesses were enrolled in our series. In clinical presentations, the most two common microbiology, imaging findings, treatment modalities, complications, and long-term outcomes. symptoms at presentation were fever and abdominal pain (90.9% and 78.8%, respectively). Moreover, abdominal pain was a major complaint symptoms and signs abdominal (such as fever, pain, diarrhea, anorexia or vomiting, signs of peritonitis and flank laboratory pain), tests[white CLINICAL SPECTRUM OF INTRA-ABDOMINAL ABSCESSES IN CHILDREN ADMITTED TO THE PEDIATRIC EMERGENCY THE PEDIATRIC TO ADMITTED IN CHILDREN ABSCESSES OF INTRA-ABDOMINAL SPECTRUM CLINICAL 1 discharge diagnosis of intra-abdominal abscesses based on their medical histories. reviewed We the medical charts of all eligible patients counts and of >10,000/μL) 63 of them (95.5%) presented with elevated CRP levels (normal range ≥8 mg/L). Of all the 66 children, 25 (37.9%) (range 1,600 to 55,500/μL) Of all (Table 2). the patients with intra-abdominal abscesses, of thempresented 54 (81.8%) with leukocytosis (WBC erythrocyte sedimentation rates, leukocytosis, and less often positive blood cultures, it is not easy for clinicians to make the definite diagnosis antibiotics therapy and percutaneous abscess drainage by US-guided or CT-guided needle aspiration (Table 3). a defect in the intestine wall or other viscus as a result of infarction, obstruction, or direct trauma. As we know, clinical presentations of attempt to find some initial clinical characteristics that could help primary emergency physicians to diagnose intra-abdominal abscesses earlier. Age, years; ICU = intensive care unit. Table 1: Table Table 2: Table .; *Statistically significant by theχ2 test or Fisher’sexact test when appropriated.

Abstracts *Statistically significant by Mann-Whitney U Test Mann-Whitney by significant *Statistically Table 3: anaerobic organisms must be administrated when intra-abdominal abscesses located in non-solid organs. non-solid in located abscesses intra-abdominal when administrated be must organisms anaerobic episodes, there were no abnormal findings on physical examination on any of the episodes. Additional studies including blood and urine analysis analysis urine and blood including studies Additional episodes. the of any on examination physical on findings abnormal no were there episodes, predict to able be would she that and order same the in occurred always episodes the that and happened” nothing like looked it episode the of end it spitting taste, saliva’s her tolerate to able not was patient the and discomfort and tiredness skin, pale of onset by accompanied were episodes episodes. She has been admitted 8 times before on ER with sudden appearance of incoercible vomiting, 2 of them requiring hospitalization. All All hospitalization. requiring them 2of vomiting, incoercible of appearance sudden ER with on before 8times admitted been has She episodes. or surgical drainage. Finally, the initial choice of antimicrobials should be based on the location of abscesses and antibiotics effective against against effective antibiotics and abscesses of location the on based be should antimicrobials of choice initial the Finally, drainage. surgical or crucial for the treatment of the disease. the of treatment the for crucial didn’t show abnormalities. Considering the symptoms, cyclic vomiting syndrome diagnosis was assumed and explained to the patient and family family and patient the to explained and assumed was diagnosis syndrome vomiting cyclic symptoms, the Considering abnormalities. show didn’t compared their creatinine levels. creatinine their compared and III) (group controls matched age healthy II) and 5(group I), 4or 1, GMFCS GMFCS 3(group 2or groups: three following the into children We divided disease. renal with or drugs nephrotoxic on test, blood of time at dehydration of signs with unwell age, of 2year than less children WBC = white blood count; Hb = hemoglobin; CRP = C - reactive protein; BUN = blood urea nitrogen; ALT = alanine aminotransferase ALT =alanine nitrogen; urea =blood BUN protein; =C-reactive CRP =hemoglobin; Hb count; blood =white WBC CYCLIC VOMITINGSYNDROMEININFANCY AND ADOLESCENCE: CASEREPORT reduced mobility is associated with a reduction in serum creatinine in otherwise well children with neurodisability compared to healthy controls. healthy to compared neurodisability with children well otherwise in creatinine serum in areduction with associated is mobility reduced good have abscesses intra-abdominal with children importantly, Most level. CRP elevated and leukocytosis pain, fever, abdominal factors, risk with appropriate counselling including prompt analgesic treatment of headache, rest and darkness as soon as prodromes begin. On a 6 month a6month On begin. prodromes as soon as darkness and rest headache, of treatment analgesic prompt including counselling appropriate with vomiting the All periods. those between state health basal her to returning patient the with 2years, last the over 2months each once usually occurred episodes These 24 hours. than less in spontaneously solving episode, per 10 8to vomits with onset, headache after 6hours 5to usually with typical onset on infancy. Primary treatment, without using targeted therapy can be effective and the involvement of patient and family is is family and patient of involvement the and effective be can therapy targeted using without treatment, Primary infancy. on onset typical with Conclusion: The authors report the case of a previously healthy 10-year-old female patient referred for a consultation due to repeated vomiting vomiting repeated to due aconsultation for referred patient female 10-year-old healthy apreviously of case the report authors The report: Case Chun Lim Chun Conclusion: vomiting syndrome (CVS), which can be an exhausting condition for children and their parents with impact on their quality of life. of quality their on impact with parents their and children for condition exhausting an be (CVS), can syndrome which vomiting prognoses when they receive diagnostic imaging studies and appropriate treatment early, with broad-spectrum antibiotics plus percutaneous percutaneous plus antibiotics broad-spectrum early, with treatment appropriate and studies imaging diagnostic receive they when prognoses Repeated vomiting episodes require a different approach and a better characterization. One of the causes of repeated vomiting is the cyclic cyclic the is vomiting repeated of causes the of One characterization. abetter and approach adifferent require episodes vomiting Repeated NEURODISABILITY WITHSEVERERESTRICTIONOFMOBILITY IS ASSOCIATED WITHREDUCEDSERUMCREATININE VALUES Pediatrics Department, Unidade Local de Saúde do Alto Minho, Hospital de Santa Luzia, Portugal; [email protected] Portugal; Luzia, Santa de Hospital Minho, Alto do Saúde de Local Unidade Department, Pediatrics follow-up period vomiting didn’t recur. There were two prodromes episodes that the patient promptly self-managed. promptly patient the that episodes prodromes two were recur. There didn’t vomiting period follow-up the “at that described mother patients’ The loss. weight no was There diarrhoea. or fever with associated was episodes these of None frequently. them: on the precedent hours the patient was usually uninterested on watching TV and had loss of appetite. Besides light de-hydration on some some on de-hydration light Besides appetite. of loss had and TV watching on uninterested usually was patient the hours precedent the on them: the episodes were characterized by a preceding non-localized headache with phono phobia, usually in the morning. Incoercible vomiting started started vomiting Incoercible morning. the in usually phobia, phono with headache non-localized apreceding by characterized were episodes the Presentation Poster Presentation Poster Francisco Ribeiro-Mourão Luton & Dunstable University Hospital NHS Foundation Trust, United Kingdom; [email protected] Kingdom; Trust, United Foundation NHS Hospital University &Dunstable Luton Data for children with neurodisability were obtained from a physiotherapy and hospital databases. The data extracted extracted data The databases. hospital and aphysiotherapy from obtained were neurodisability with children for Data Methods: and Materials included age, gender, diagnosis and categories of Gross Motor Function Classification System (GMFCS) score, weight, creatinine level, drug drug level, creatinine weight, score, (GMFCS) System Classification Function Motor Gross of categories and diagnosis gender, age, included 157 /PO1:ID: 29 ID: 113ID: /PO1: 30 Introduction: history and comorbidities. Age matched controls without neurodisability were obtained from phlebotomy records. Exclusion criteria were were criteria Exclusion records. phlebotomy from obtained were neurodisability without controls matched Age comorbidities. and history whether We investigated levels. creatinine reduced have can malnutrition to due mass muscle low with Patients Purpose: and Introduction ALT (U/L) Intraperitoneal abscess Creatinine (mg/dl) Pelvic abscess Renal abscess Periappendical abscess Sodium (mmol/L) Potassium (mmol/L) Liver abscess Location ofabscesses PO1: POSTER PRESENTATIONS: 1 SESSION Clinical management of patients with intra-abdominal abscesses intra-abdominal with patients of management Clinical , Marianne Phillips, Liam Watson, Michael Eisenhut Michael Watson, Liam Phillips, , Marianne 20 9 t h Cyclic vomiting syndrome is a functional disorder consisting of stereotypical episodes of vomiting separated by weeks to months, months, to weeks by separated vomiting of episodes stereotypical of consisting disorder afunctional is syndrome vomiting Cyclic Primary physicians should keep the diagnosis of intra-abdominal abscesses in mind when children present with predisposing predisposing with present children when mind in abscesses intra-abdominal of diagnosis the keep should physicians Primary

E Vomiting is a frequent cause of pediatric ER admissions and is associated with a large number of numerous conditions. conditions. numerous of number alarge with associated is and ER admissions pediatric of cause afrequent is Vomiting D I T 1 I O 7 N Topics: Topics: N Total(n=66) , Vera Gonçalves, António Pedro Marinho, Mariana Branaco, Ana Rita Araújo Rita Ana Branaco, Mariana Marinho, Pedro António Gonçalves, , Vera 14 25 17 38 38 25 25 6 4 General Pediatrics, Gastroenterology &Metabolism Gastroenterology Pediatrics, General General Pediatrics General % 25.8 37.9 21.2 CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 134.05 9.1 6.1 18.92 0.62 3.67 Antibiotics N 13 (n=25)

2 2 7 only 1 25.82 3.83 0.43 0.19 28.0 52.0 % 8.0 8.0 4.0 Management 13 11 11 Percutaneous 7 7 N aspiration 0 3 4 2 2 (n=11) 136.29 22.36 0.62 3.87 %

27.3 36.4 18.2 18.2 0.0

10 16 N 17.85 Surgery (n=30) 0 0 4 0.18 3.09 0.52 33.3 13.3 53.3 % 0.0 0.0 0.033* 0.346 0.134 0.805 POSTER SESSION 1 SESSION POSTER P-value <0.001 93

Abstracts 94 1 POSTER SESSION 1 , Květa Bláhová 1

, Veronika Stará 3 , Petr Bukovský 2 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE Gastroenterology & Metabolism Gastroenterology & Metabolism , Michal Rygl 2 Children’s Heart Centre, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, 3 Topics: Topics: N Department of Paediatric Surgery, 2nd Faculty of Medicine, Charles Universityin Prague and University Hospital Motol, 7 O 2 I 1 T I D The Denver shunt is a system used for drainage of ascitic fluid to the circulatory system. It contains a unidirectional pump that Connective tissue pathology is a base of formation chronic diseases in children and associated with an expressed E

Thus, CTD in adolescents is characterized by low level of interstitial collagens in gastric-duodenal mucosa, and accompanied Children with neurodisablility with mobility restriction requiring physical assistance or powered mobility in most or all settings h , Jiří Náhlovský t 1 9 20 Gastrointestinal involvement against the backgroundof the CTD is characterized primarily by motility disorders, including 180 children 180 were included: 25 children in group I, 65 in group II, and 90 in group III. Age and gender were not different between PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: Department of Pediatrics, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic, by specific disorders in immunological reactivity, that is the basis of formation of motility disorders with the subsequent development of between patients with neurodisability (mean 32.2 compared SD 9.4) to patients without (mean 36.5 There SD 9.8). was no significant difference ID: 259 32 / PO1: Introduction: Inna Yakovleva Introduction: ID: 228 31 / PO1: is placed subcutaneously over the ribs. This allows use of external manual compression to move fluid from the peritoneal cavity to the central is accompanied by decrease in a mucosa functional ability with development of the valve-sphincter failure. The form of mucosal lesionsis a chronic non-atrophic gastritis with simultaneous inflammation in the antral and fundal parts. Duodenal ulcerwas identified rarely immunity is characterized by depressive state, which is manifested by CD4+ reduction P<0,05) (39,5%; and CD8+ reduction (8,8%, P<0,001), immunity. Complex evaluation of immunity and connective tissue parameters was carried out using the system correlation analysis. immunodeficiency. Many connective tissue disorders (CTD) carry high risks for life-threatening heart and bloodvessel conditions. Gastrointestinal in creatinine level ( p=0.953) between GroupI (mean 35.9 SD9.5) and Group III (mean35.8 A significantly SD 9.5). lower creatinine level in the right atrium was detected and treated with low molecular heparin. The patient also has a right-sided chylothorax for which repeated 65 peers without CTD were included in the comparison group. Collagens content in the lamina propria of gastric-duodenum mucosa was Materials and Methods: Inflammatory-destructive diseases of gastroduodenal tract were studied155 adolescents yearsin 18 11 to of age. IMPACT OF CONNECTIVE TISSUE DISORDERS ON THE FORMATION OF GASTROINTESTINAL PATHOLOGY IN ADOLESCENTS IN PATHOLOGY OF GASTROINTESTINAL DISORDERS ON THE FORMATION OF CONNECTIVE TISSUE IMPACT Filip Fencl Poster Presentation tissue matrix of the mucosa is characterized by structural transformation of collagen fibrils(wrong orientation, focal sclerosis, immaturity). It Results: tract, as it contents a lot of collagen, may also be impacted with the subsequent development of inflammatory-destructive damages. Purpose: This study aimed to evaluate the significance of collagen level content and the state of immunological reactivity in the formation of Poster Presentation Results: Prague, Czech Republic; Prague, Czech Republic; [email protected] prevention of reflux disease and correction of immune system in adolescents with CTD. venous system. venous peculiarities of gastroduodenal pathology in adolescents. vein thrombosis on the left Due side). to massive ascites and breathing difficulties, repeated ascites punctures were needed(first at 2 months punctures of the fluid are required. Czech Republic; Case report: present We a 3-year old female patient with generalised lymphedema, chylous ascites and right-sided chylothorax on the basis while the B-system of immunity works in the activation mode with hyperproduction of antibodies to collagen and elastin. Conclusion: Conclusion: manifestation of gastroduodenal pathology in adolescents with CTD are formed against the background of an increase in functional activity number (60,9%, comparison and the P<0,001) phagocytic group - 77,5%; index comparison (5,3; The T-system of P<0,001). group - 7,3; microscope with using light filters. Immunologic homeostasis has been studied according to the monocyte-phagocytic, humoral and cell links of Institute of Children and Adolescents Health Care - National Academy of Medical Sciences of Ukraine, Ukraine; [email protected] CHYLOTHORAX - FIRST EXPERIENCE IN THE CZECH REPUBLIC 1 drainage malfunctions were only short-term and repeated compressions of the catheter led to its unblocking. the At age of 2.8 years, thrombus of glomerular filtration rate. of dysplasia of the lymphatic system. Polyhydramnion, fetal hydrops and ascites were present since the 30th week of pregnancy. Postnatal conservative therapy, including total/ partial parenteral nutrition from months 3 to 12 of age, special diet, pharmacotherapy (diuretic therapy For theseof age). reasons, the insertion of a peritoneoatrial Denver shunt was indicated at 2 years of age. Ascites drainage is still functional, gastritis and esophagitis against the backgroundof reflux. The work provides grounds for employing rehabilitation measures connected with a of monocyte-phagocytic link cells accompanied bypronounced a deficiency of phagocytic cells in the form of a decrease in the phagocytic gastroesophageal reflux disease, reflux-gastritis (77%; comparison group - 29%, and a P<0,001) reducedlevel of interstitial collagens. The groups, withchildren with and without neurodisability having a mean age of 5.6. Creatinine values were significantly different (p=0.003) (10,0%; comparison(10,0%; group - 33,8%; P=0,035), and it was accompaniedby detection of Helicobacter pylori.It has been revealed that clinical (p=0.001) was found in group II (mean 30.7 SD 9.1) compared(p=0.001) was found in to group group SD II III 9.1) (mean (mean SD 30.7 36.7 10.0). (GMFCS 4 or have a significantly 5) lower serum creatinine compared to healthy controls and may need a lower reference range for estimation evaluated by immunohistochemistry with using monoclonal antibodies of collagen 3, 5 types. 4, 1, Biopsy samples were studied in luminescent average immunofluorescence intensity of collagen types 1 and 3 in patients with CTDwas significantly The (P<0,01). connective lower and albumin substitution), was unsuccessful. Long-term parenteral nutrition is limited by poor access to the central venous system (subclavian THE USE OF DENVER SHUNT IN A PATIENT WITH CONGENITAL LYMPHEDEMA, CHYLOUS ASCITES AND ASCITES CHYLOUS LYMPHEDEMA, WITH CONGENITAL PATIENT A THE USE OF DENVER SHUNT IN The traits of the including CTD, the Marfan syndrome, were determined relying on the Ghent criteria. CTD were revealed in 90 adolescents.

Abstracts 1, maximum 30 days), 8 with classic simple virilizing (average age of diagnosis 3.1 years; minimum 0 days, maximum 7 years) and 13 with 13 and with 7years) maximum 0days, 3.1 minimum years; diagnosis of age (average virilizing simple days), classic 30 8with 1, maximum antiemesis agents and NPO. The general data, final diagnosis, clinical manifestations, medical managements, NPO duration, and lab data data lab and duration, NPO managements, medical manifestations, clinical diagnosis, final data, general NPO. The and agents antiemesis refeeding. to failed that reasons possible the analysis and vomiting, and pain abdominal acute with patients the for duration NPO ideal the for looking to aimed study The hypoglycemia. and dehydration in result may refeeding a late analysis of CYP21A2 was performed and genotype-phenotype correlation was established. was correlation genotype-phenotype and CYP21A2 of performed was analysis anomaly cause mild to severe microcytic anaemia. The differential diagnosis between thalassemia (minor type) and anaemia due to iron iron to due anaemia and type) (minor thalassemia between diagnosis differential The anaemia. microcytic severe to mild cause anomaly (79.6%) were the most symptoms. Among them, antiemesis agents were used in 160 patients (52.6%). The patients with NPO duration of 4 4 of duration NPO with (52.6%). patients The 160 patients in used were agents antiemesis them, Among symptoms. most the (79.6%) were gmail.com groups suffering from anaemia: thalassemia patients and AID patients. The end-point aim was to improve thalassemia diagnosis and to to and diagnosis thalassemia improve to was aim end-point The patients. AID and patients thalassemia anaemia: from suffering groups overall concordance between genotype and phenotype was 79%. Genotype accurately predicted phenotype of patients with classic salt salt classic with patients of phenotype predicted accurately Genotype 79%. was phenotype and genotype between concordance overall conceive an algorithm for thalassemia diagnosis. thalassemia for algorithm an conceive deficiency (AID) is frequent difficult. Purpose. The authors analysed the differences regarding haematological indices between 2 children- 2 between indices haematological regarding differences the analysed authors The Purpose. difficult. frequent is (AID) deficiency 1 1 CORRELATION CONGENITAL ADRENAL HYPERPLASIA DUETO 21-HYDROXYLASE DEFICIENCY: GENOTYPE-PHENOTYPE Wen Chieh Yang Chieh Wen University of Sibiu, Romania.; [email protected] Romania.; Sibiu, of University nonclassical form (average age of diagnosis 6.9 years; minimum 4 years, maximum 17 years). The most frequent genetic defects in the classic classic the in defects genetic frequent 17 most years). The maximum 4years, minimum years; 6.9 diagnosis of age (average form nonclassical years), 11,0-11,9 haemoglobin to (age g% 12-14 according evaluated were 11,0-12,9 (age >15 and years) patients years). All respectively g% was the major part (43.8%), followed by adult patients (33.6%). Except abdominal pain and vomiting, nausea (93.1%) and abdominal distension (93.1%) distension nausea abdominal vomiting, and and pain abdominal (33.6%). Except patients adult by (43.8%), followed part major the was analyzed. were But refeeding. early after vomit still may patients the and tolerant be maynot refeeding early An pysician. by recommended be generally would Conclusion: respectively. 86%, and 100% 75%, in mutations nonclassical and virilizing simple classic wasting, Conclusion: Conclusion: Taiwan;CCH, [email protected] CYP21A2 mutation phenotype doesn’t correlate precisely with the genotype, suggesting that other genes influence the clinical manifestations. manifestations. clinical the influence genes other that suggesting genotype, the with precisely correlate doesn’t phenotype CYP21A2 mutation variation and there are general, but not precisely, correlation between genotype and phenotype. and genotype between correlation precisely, not but general, are there and variation period. According to age, mild type anaemia correspond to following haemoglobin-ranges: 10,0-10,9 (age g% 1-5 years), 11,0-11,4 haemoglobin-ranges: following to (age g% 6-11 correspond anaemia type mild age, to According period. patients has abdominal distension has 10.6 times odd’s ratio of refeeding failure. refeeding of ratio odd’s 10.6 has times distension abdominal has patients Furthermore, molecular analysis of CYP21A2 provides useful information in prediction of disease severity, genetic and prenatal counseling. prenatal and genetic severity, disease of prediction in information useful CYP21A2 of provides analysis molecular Furthermore, HOW LONGISTHEIDEAL NPODURATION FORVOMITINGPATIENTS? 21-hydroxylase deficiency. CYP21A2 allelic with correlates severity disease’s the cases of majority the In CYP21A2 the by gene. encoded enzyme the 21-hydroxylase, frequency and abdominal distension should have prolonged NPO duration. NPO prolonged have should distension abdominal and frequency forms were I2 splice (22%), V281L I172N the splice (13%) form, (71%). I2 (19%), were forms Q318X F306+nt by and The (13%) followed nonclassical the in and Denver shunt is a safe method for treating of refractory ascites in small children and improves the quality of life of these patients. these of life of quality the improves and children small in ascites refractory of treating for method asafe is shunt Denver Presentation Poster NPO. The before frequency vomiting higher had NPO during even vomited (3.7%). patients failure The refeeding of rate lower has 6hours to Results: Results: with patients Portuguese of acohort in correlation genotype-phenotype evaluate CYP21A2 of and spectrum mutational the Describe Purpose: Presentation Poster Presentation Poster Sorin Ioan Iurian Ioan Sorin Methods: Retrospective study of 28 patients with clinical and biochemical diagnosis of 21-hydroxylase deficiency. Molecular Molecular deficiency. 21-hydroxylase of diagnosis biochemical and clinical with patients 28 of study Retrospective Methods: and Material The authors selected 87 patients (age between 1-18 years) with microcytic anaemia (mild type) during a12 month- during type) (mild anaemia 1-18 (age microcytic between with years) patients 87 selected authors The Methods: and Material IMPROVEMENT OFBETA-THALASSEMIA DIAGNOSISINCHILDREN level, red blood cell count (RBC), red blood distribution width (RDW), mean cell volume (MCV), haemoglobin electrophoresis, Coombs test test Coombs electrophoresis, haemoglobin (MCV), volume cell (RDW), mean width distribution (RBC), blood red count cell blood red level, PO2: 46 PO2: to 127 /PO1: (Moved ID: 35 Introduction: Introduction: ID: 140 /PO1:ID: 34 Inês Falcão Inês ID: 293 /PO1: 33 293 ID: Introduction: Pediatric Clinic Hospital from Sibiu, Romania, Romania; Romania; Romania, Sibiu, from Hospital Clinic Pediatric Centro Materno Infantil do Norte – Centro Hospitalar Universitário do Porto; Porto; do Universitário Hospitalar –Centro Norte do Infantil Materno Centro PO1: POSTER PRESENTATIONS: 1 SESSION The major diagnoses in sequence were acute gastroenteritis (82.9%), acute gastritis and colitis. The patients aged less than 6 years 6years than less aged patients The colitis. and gastritis (82.9%), acute gastroenteritis acute were sequence in diagnoses major The Genotyping was performed in 28 unrelated patients: 7 with classic salt wasting (average age of diagnosis 14.9 days; minimum 14.9 days; minimum diagnosis of age (average wasting salt classic 7with patients: unrelated 28 in performed was Genotyping We retrospectively recruited 304 patients with the chief complaints of abdominal pain and vomiting and received the therapies of of therapies the received and vomiting and pain abdominal of complaints chief the with patients 304 recruited We retrospectively 20 9 t h 1 In this study there was a high genotype-phenotype correlation, as described in other studies. Despite the high concordance, the the concordance, high the Despite studies. other in described as correlation, genotype-phenotype ahigh was there study this In We demonstrate our experience from the first use of the Denver shunt in the Czech Republic. Our case report confirms that that confirms report case Our Republic. Czech the in shunt Denver the of use first the from experience our We demonstrate For patients in the acute phase of vomiting, NPO of 4 to 6 hours was recommended and the patients with higher vomiting vomiting higher with patients the and recommended was 6hours 4to of NPO vomiting, of phase acute the in patients For

E , Catarina Mendes , Catarina During the acute phase of vomiting, even small amount of water may be intolerant by mouth. Therefore, nothing by mouth (NPO) (NPO) mouth by nothing Therefore, mouth. by intolerant be may water of amount small even vomiting, of phase acute the During Congenital adrenal hyperplasia is a common autossomal recessive disorder caused mainly by defects in the steroid steroid the in defects by mainly caused disorder recessive autossomal acommon is hyperplasia adrenal Congenital Beta-thalassemia represent a spectrum of genetic disorders characterized by insufficient synthesis of beta-globin chains. This This chains. beta-globin of synthesis insufficient by characterized disorders genetic of aspectrum represent Beta-thalassemia D I T 1 I O 7 1,3 N , Liana Bera , Liana Topics: Topics: Topics: General Pediatrics General Gastroenterology & Metabolism, Emergency Pediatrics Emergency &Metabolism, Gastroenterology Endocrinology &Growth. Endocrinology 2 2,3 , Catarina Carvalho , Catarina CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER ) 2 , Joana Freitas , Joana 2 Department of Statistics, Faculty of Medicine, Sibiu, Romania; Romania; Sibiu, Medicine, of Faculty Statistics, of Department

1 , Maria João Oliveira João , Maria 2 Centro Hospitalar Tâmega e Sousa; inespatriciofalcao@ eSousa; Tâmega Hospitalar Centro POSTER SESSION 1 SESSION POSTER 1 , Helena Cardoso , Helena 1 , Teresa Borges , Teresa 3 Lucian Blaga Lucian 1 95

Abstracts 96 POSTER SESSION 1

, Alexandra Martins, Magalys Pereira, Miguel Costa POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE Infectious Diseases & Vaccines, Allergy, Immunology & Pulmonology Emergency Pediatrics, Neurology Topics: Topics: N 7 O I , Kwanghoon Kim, Hye-Young Kim 1 T I D Atopic dermatitis is a chronic recurrent inflammatory skin disease that characterized by pruritus,xerosis and typical eczema. In Migraines are a common cause of recurrence to the emergency department,commonly presenting a diverse etiology. In the E

We report We a atopic dermatitis patient with invasive candidiasis. Untreated atopic dermatitis can lead to severe systemic infection. We remarked We a strong correlation between thalassemia (minor type) and haematologicalparameters / haematologicalindices: Migraines are a common complaint in pediatrics, prevalence with a 5.9 in the to 37.7% emergency room. Most of these situations h t 9 20 PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: became edematous and had difficulty extendingin both knees. One day before admission she came to local clinic forvaccination. On physical Introduction: / PO1: 37 / PO1: ID: 211 Introduction: ID: 226 36 / PO1: 3 day course as well as aqueous vomiting that began hours before his arrival. He comes from a poor social background, with soft drugs MCV(reduced), RBC (increased), (increased), RDW Sirdah Ricerca 27) The Menzer and authors (< 4.4), index Ehsani 13), (< 15). (< (< Discussion: Benedita Sousa Amaral Bianchi de Aguiar this condition, patients easily suffered from secondary infection with bacteria, virus or fungus due to vulnerable skin barrier. Here we introduce transfusion, her platelet count continuously dropped.Empirical antibiotics were changed to vancomycin in combination with cefotaxime, and Poster Presentation However, thisHowever, clinical case should prompt are attention to the importance of a thorough physical and neurological examination, as well the third ventricle and consequent expansion of the left ventricle withperi lesional bleeding. Hewas then sent to a central hospital in orderto be Despite a discrete asymmetry of the muscular strength in the upper limbs he had a normal neurological examination. During his stay he Poster Presentation thalassemia. In order to compare both groups from haematological point of view, the authors have examined 8 haematological indices for all followed directions and performed folk remedies, believing her skin could improve naturally. From one month before admission, her both legs Proper parental education for careful skin care is important for treatment of atopic dermatitis. Pusan national university hospital, Korea, Republic of [email protected] (South Korea); Ehsani indices concerning difference between both microcytic anemias 90%). (> Reattempted blood culture showed growth of Candida albicans after 2 days. The patientstreated with antifungal agentfor about four weeks pediatric phase, in particular with adolescents, there are some particularities that can sometimes complicate the diagnosis of certain disorders. vital signs were blood pressure, 80/50 mmHg, heart times rate, 148 per minute, respiratory rate times 24 per minute, body temperature 36.4℃, progressed to his face and lower limbs, impeding autonomous walking. The only alteration present in the blood work was a thrombocytopenia patients: Mentzer, England and Shine Fraser, and Lal, Srivastava, Green and King, Ricerca, Sirdah and Ehsani indices. Data was statistically previous month or other haemolytic anemias (autoimmune, enzyme deficiencies, microspherocytosis). No patient has simultaneously AID and proposed a diagnosis-algorithm for thalassemia minor. value The < 0.05). authors noticed a high sensitivity, specificity and positive and negative predictivevalues for Mentzer, Ricerca, Sirdah und Conclusion: Case Report: A 8-month-old girl presented with eczematous skin rash on whole body for 3 days. From age of 40 days, the girl had Case report: A previously healthy year old 16 adolescent, was brought to the emergency room due to bilateral frontal migraines with a Centro Hospitalar Entre Douro e Vouga, Portugal; [email protected] with specific IgE, >100 eggKUA/L, white, >100 KUA/L, soy bean, milk, 96.6 KUA/L, wheat, 45.2 KUA/L. Intravenous antibiotics, first generation Conclusion: maintained vomiting and started to become drowsy and less responsive. His neurological deficits(sensitive and motor) on the right hand side Initial blood and urine cultures had no growth and laboratory findings become improved. vancomycinSo and fluconazole were stopped. After specific IgE 1.05for egg,KUA/L. Shewas educated to try careful skin care with emollient and topical corticosteroid, but her parents didn’t recommended when a cerebral organic disease is suspected. regarding for thalassemia RBC MCV and (mean was value) 5.41 RDW. group and for 4.31 AID patients, with significant statistical difference (p dermatitis, she was diagnosed with atopic dermatitis at 3 months by physician in the local clinic. that At time laboratory test showed elevated one case of severe atopic dermatitis with invasive candidiasis. oxygensaturation, 97%. Laboratory tests showed WBCa count of 6880/uL, segmenteda percentage of 70.2%, hemoglobin g/dL, of 0.6 platelet count of 68000/uL, C-reactive protein of 12.29mg/dL, total protein 2.5 mg/dL, albumin g/dL. 1.0 Serum total IgE was elevated as 5942 IU/mL cephalosporin with clindamycin and total parenteral nutirition were given upon a diagnosis of skin infection and malnutrition. Despite repetitive fever 38.2℃one day, was checked and then blood culture was done again. Fluconazole was re-injected consideringinvasive candidiasis. consumption, although denying he had done so in the last week. When he was first assessed he presented as conscious and collaborative. of 20.000x109. He then undertook a cranial computed tomography scan which (CT), revealed a round 4.5 by 5cm lesion with compression of erythematous and pruritic eczema on face. Considering relapsing episodes of pruritic dermatitis on typical area and maternal history of atopic examination oral thrush and severe eczema on whole body with very poor condition were noted, and she was referred to our hospital. Initial (49 patients).(49 Inclusion criteria: increased haemoglobin A2 level based on haemoglobin electrophoresis(first group) and normal haemoglobin evaluated by neurosurgery, who subsequently subjected him to surgery where an atypical central neurocytoma was diagnosed. and educated to general skin care for atopic dermatitis. antifungal agent, fluconazolewas added upon suspicion of sepsis and disseminated intravascular coagulation rather than simple skin infection. and ferritin level. Then the patients were divided in 2 groups: first group confirmed with thalassemia (38 patients) and the second one with AID are caused by extracranial or psychosomatic conditions. Serious intracranial conditions amount to a small, non-representative percentage. integrationas it´s with the medical history. Every case should be evaluated individually and it is important to remember that cranial CT is analyzed using independent sampleT test and likelihood ratio. Results. observed We significant statistical difference between groups A2 level for the second group. Exclusion criteria: age under beta-thalassemia 1 year, major type, blood transfusion or bleeding episode during Youngeun Roh A CASE OF ATOPIC DERMATITIS WITH INVASIVE CANDIDIASIS WITH INVASIVE DERMATITIS ATOPIC CASE OF A “WHEN MIGRAINES ARE MORE THAN WHAT THEY SEEM…” THEY ARE MORE THAN WHAT “WHEN MIGRAINES

Abstracts ACADEMIC PERFORMANCEIN ADOLESCENTS –BIOLOGICAL,SOCIAL AND BEHAVIORAL DETERMINANTS. Aim: All considered themselves happy and reported having friends; 57.9% had a best friend and 86.7% reported to have a confident (their (their aconfident have to reported 86.7% and friend abest 57.9% had friends; having reported and happy themselves considered All a positive impact on the local protective factors of the upper respiratory tract such as lysozyme, slgA, cell elements of nasal secretions. nasal of elements cell slgA, lysozyme, as such tract respiratory upper the of factors protective local the on impact a positive Vera Vavilova Vera attending their 15th year global health consultation was assessed following a HEEADSSS psychosocial interview. School outcomes (pass/ outcomes School interview. psychosocial aHEEADSSS following assessed was consultation health 15th global year their attending completing 12th grade (p=0,039/p=0,073), father smoking (p=0,048); it was also more common if regular medication, parents divorced and and divorced parents medication, regular if common more also was it (p=0,048); smoking father (p=0,039/p=0,073), grade 12th completing great screen time/day (p=0,061/p=0,085/p=0,078). Change of curricula to vocational area was associated with parental divorce (p=0,006), (p=0,006), divorce parental with associated was area vocational to curricula of Change (p=0,061/p=0,085/p=0,078). time/day screen great coverage among children. The group taking Anaferon for children showed that over a year period the incidence rate of acute respiratory infection infection respiratory acute of rate incidence the period ayear over that showed children for Anaferon taking group The children. among coverage 1 1 1 region 15q11-13, have recently been reported to cause Schaaf-Yang syndrome. cause to 15q11-13,region reported been recently have nasopharyngeal diseases. showed also drugs active release and vaccination The group. control the in than =0,279) (p less 1.5 and times —1.2 =0,467) (p sinusitis maxillary reported liking school (86.8%) and studying ≥1h/day (60%), 84.2% alone, 31.6% listening to music; 52.6% attended study support groups. support study attended 52.6% music; to 31.6% ≥1h/day alone, listening (60%), studying 84.2% (86.8%) and school liking reported rate was 68.4%; 47.4% of the mothers and fathers completed 12th grade, with 86.8% of both having a job. 84.2% had at least one brother and and brother one least at had 84.2% ajob. having both of 86.8% with 12th grade, completed 68.4%; was 47.4% fathers rate and mothers the of associations and assessed retrospectively were system) school regular vocational/maintaining to transition failure, subject any/no grade, repeat SHAAF YANG SYNDROME-CASEREPORT with chronic nasopharyngeal diseases. nasopharyngeal chronic with was 1.2 times less (p <0,022), pneumonia — 1.4 times less (p =0,354), acute bronchitis —1.2 times less (p =0,374), acute otitis media and chronic chronic and media —1.2 =0,374), (p otitis less acute times bronchitis acute =0,354), (p —1.4 less times pneumonia <0,022), (p less 1.2was times most reported good family relations (71.1%); 71.1% didn’t share their room, and 44.7% were engaged in house chores. Ninety-two percent percent Ninety-two (71.1%); chores. relations house in family good engaged were 44.7% and 71.1% room, reported most their share didn’t Conclusion: after 22 pm every day. Regarding school performance, 10.5% had school retention that year, 76.5% of those who passed had no subject subject no had passed who those of 76.5% year, that retention school had 10.5% performance, school day. Regarding every pm 22 after Carmén Silva Carmén A boy, first born of a nonconsanguineous couple. Family history of trisomy 21 on the maternal side and clubfoot and anencephaly anencephaly and clubfoot and side maternal the on 21 trisomy of history Family couple. nonconsanguineous of a born Aboy, first report: Case were on regular curriculum and 84.2% attended public schools; 34.2% had ≥1 school retention and 36.8% had changed school that year. Most year. that Most school changed had 36.8% and retention ≥1 had school 34.2% schools; public attended 84.2% and curriculum regular on were with the clinical information were evaluated using the SPSS® v.20. SPSS® the using evaluated were information clinical the with Conclusion: professional and personal achievements. personal and professional [email protected] Portugal; Ocidental, 4 NEW ARGUMENTS FORDOUBLE ACTION RELEASE ACTIVE DRUGS AMONG CHILDRENWITHCHRONICSITESOF Results: factors determining academic performance. academic determining factors Presentation Poster Presentation Poster tests. Fetal echocardiogram was normal. He was born at 41 weeks of gestation, after an emergent C-section delivery. APGAR at 1’/5’/10’ at APGAR delivery. was C-section emergent an after 41 at gestation, of born weeks was He normal. was echocardiogram Fetal tests. Presentation Poster atimely for evaluation bio-psycho-social astructured have should adolescents All time/day. screen great and divorce parental 12th grade, the To characterize the biological, social, behavioral and academic features of a primary care setting adolescent population and identify identify and population adolescent setting care aprimary of features academic and behavioral social, biological, the To characterize Purpose: Results: mother not completing 12th grade (p=0,041), studying accompanied (p=0,053) and great screen time/day (p=0,017). time/day screen great and (p=0,053) accompanied studying (p=0,041), grade 12th completing not mother not father/mother (p=0,003), victim abullying being with associated were failure subject outcomes/any academic school with Poor year. that failure associated was (p=0,047) dating and (p=0,029) accompanied Studying program. avocational to 21.1% and changed failure, bed to going 76% with 8,8h, was week school during sleep night Mean victim. abullying been having reported 18.4% 39.4%). in mother Hugo Tavares Hugo Materials: Maria Isabel Bento Ayres Pereira Leite Pereira Ayres Bento Isabel Maria INFECTION INNASOPHARYNX. Retrospective longitudinal observational study conducted in 2015. Bio-psycho-social information of adolescents adolescents of information 2015. in Bio-psycho-social conducted study observational longitudinal Retrospective Methods: and Materials immunoglobulin A (slgA) in nasal secretions were evaluated. were secretions nasal in A(slgA) immunoglobulin secretory and activity lysozyme analyzed, were ratio population cell main the and elements cell of number total the addition, In infections. ID: 231 /PO1: 231 38 ID: ID: 282 /PO1: 40 282 ID: in the paternal family. A pre-natal diagnosis of bilateral clubfoot was performed and amniocentesis was made with normal karyotype and Array Array and karyotype normal with made was amniocentesis and performed was clubfoot bilateral of diagnosis Apre-natal family. paternal the in Introduction: identification and holistic intervention on the determinants affecting school performance, literacy, and adult professional success. professional adult and literacy, performance, school affecting determinants the on intervention holistic and identification Introduction: ID: 100 /PO1: 100 39 ID: Unit of Neurodevelopment - São João Hospital, Porto; Porto; Hospital, João -São Neurodevelopment of Unit Pediatric Department, Centro Hospitalar Vila Nova de Gaia Espinho, Portugal; Portugal; Espinho, Gaia de Nova Vila Hospitalar Centro Department, Pediatric Kemerovo State Medical University, Russian Federation; Federation; Russian University, Medical State Kemerovo Pediatric Rehabilitation Unit - North Rehabilitation Center, Porto; Center, Porto; Rehabilitation -North Unit Rehabilitation Pediatric PO1: POSTER PRESENTATIONS: 1 SESSION To evaluate the results of the prospective comparative study on efficacy of use of Anaferon among 994 children (aged from 2 to 5 years) to 5 years) 2 from (aged children 994 among Anaferon of use of efficacy on study comparative prospective the of To results the evaluate It was shown that use of Anaferon for children during a 1-month period beginning 10 days prior to vaccination increases vaccination vaccination increases vaccination to 10 prior days beginning period a1-month during children for Anaferon of use that shown was It Thirty-eight adolescents were identified, 55.3% boys, 26.3% with a health problem and 21.1% on regular medication. Parent divorce divorce Parent 21.1%and problem medication. health regular a on with 26.3% boys, 55.3% identified, were adolescents Thirty-eight The study period: December 2011 to April 2015. Presents a comparative analysis of the incidence rate of respiratory and ENT- and respiratory of rate incidence the of analysis acomparative 2011 2015. Presents April to December period: study The 20 9 t h The study showed good tolerability of Anaferon for children and PCV13, safety of its use among children with chronic chronic with children among use its of PCV13, and safety children for Anaferon of tolerability good showed study The Bad school results determinants identified were dating, studying accompanied, being a bullying victim, parents not completing completing not parents victim, bullying a being accompanied, studying dating, were identified determinants results school Bad

E Truncating mutations in the maternally imprinted, paternally expressed gene MAGEL2, which is located in the Prader-Willi critical critical Prader-Willi the in located is which MAGEL2, gene expressed paternally imprinted, maternally the in mutations Truncating Adolescents academic performance is determined by their biological and environmental milieu and may influence future future influence may and milieu environmental and biological their by determined is performance academic Adolescents D 1 1 1 Marta Rosário , Marta , Alexander Vavilov , Alexander I T 1 I O 7 N Topics: Topics: Topics: General Pediatrics, Adolescent Health Choices Health Adolescent Pediatrics, General Rare Diseases, Infant Development Infant Diseases, Rare General Pediatrics, Allergy, Immunology &Pulmonology Immunology Allergy, Pediatrics, General 2 , Isabel Vieira , Isabel 1 CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER , Asya Cherkaeva , Asya 1 , Andreia Ribeiro Andreia , 3 , Renato Nunes , Renato 2 1 , Irina Nechaeva , Irina Pediatrics - São João Hospital, Porto; Porto; Hospital, João -São Pediatrics 2 Pediatric Clinic; [email protected] Clinic; Pediatric 1 , Cátia Leitão Cátia , 4 , Micaela Guardiano , Micaela 5 Genetics - São João Hospital, Porto; [email protected] Porto; Hospital, João -São Genetics

2 1 , Alla Evstratenko , Alla , Ana Esteves Luísa 2 Unidade de saúde familiar Serpa Pinto, ACES porto ACES Pinto, porto Serpa familiar saúde de Unidade POSTER SESSION 1 SESSION POSTER 1 , Miguel Leão , Miguel 2 3 Association of Cerebral Palsy, Porto; Cerebral of Association 2 , Ana Luísa Leite Luísa Ana , 5 1 , Conceição Macedo 97 2 ,

Abstracts 1 98 Department of 2 , Henrieta Hudečková 3 0 Percentage 100 POSTER SESSION 1 Department of Health Psychology, Faculty of Medicine, 3 0 50 Number of infants , Zuzana Dankulincová Veselská 3 Response to the treatment = 50) (n

No effects No Excellent Response Umbilical granuloma, Common salt, Infants Table 2: Table , Daniela Husárová 2 8 Percentage 20 72 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE , Zuzana Boberová 1 General Pediatrics Keywords: Adolescent Health Choices, Adolescent Wellbeing Topics: Topics: Number of infants 36 4 10 , Tibor Baška N 1 7 O I 1 T I D Eating habits rank among the most important health determinants. Development of healthy eating habits during childhood and Umbilical granuloma isa common umbilical abnormality in neonates and young infants. It is usually noticed by the parents because E

Children possess general principles of healthy eating habits but they do not implement them in their life. Preventive measures The use of common salt in treating umbilical granuloma is simple, cost-effective, curative, and safe. It is easily administered and Schaaf-Yang syndrome Schaaf-Yang is a Prader-Willi-like disease that manifests as developmental delay/intellectual disability, hypotonia, h t 9 20 All 50 infants with umbilical granuloma showed complete resolution after the 5-day course of common salt treatment. Schoolchildren expressed adequate knowledge on healthy eating habits. the However, attraction of sweets is much stronger than Age group distribution = 50) (n PO1: POSTER PRESENTATIONS: SESSION 1 PRESENTATIONS: POSTER PO1: 9 - 12 3 - 8 Age group (weeks) 13 - 16 13 Department of Public Health, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Slovakia; / PO1: 42ID: 158 / PO1: Introduction: habits can be also associated with knowledge deficit in this area. Introduction: it could ooze and present with persisting irritation for several months. Many treatment modalities are available for umbilical granuloma such as instability with hyperthermia and excessive sweating. Body dysmorphic disorders wereevident over time: dolichocephalic with bitemporal ID: 289 41 / PO1: 97 percentile.97 He was hospitalized up to 2 months for food difficulties with frequent situations of regurgitation, being necessary nasogastric 6/8/10, being resuscitated with bag-hand-mask and oxygen. Weight and length was inferior to percentile 3 and cephalic perimeter was in the INTERPRETATIONS OF SCHOOLCHILDREN ON THE HEALTH BEHAVIOUR IN SCHOOL-AGED CHILDREN (HBSC) BEHAVIOUR OF SCHOOLCHILDREN ON THE HEALTH INTERPRETATIONS Materials and Methods: Data were collected in selected elementaryschools from April to November 13 Pupils 2015. of 5th to 9th grade (11, Materials and Methods: This prospective study was conducted on 50 infants, their ages both weeks 3–16 boys [Table 1], and girls, with Biology Didactics, Faculty Šafárik J. of Science, University P. in Košice, Slovakia; King Abdualziz Medical City, Saudi Arabia; [email protected] Results: Poster Presentation Results: Purpose: Understanding the opinions, attitudes and knowledge of schoolchildrenregarding eating habits is essential to develop effective Purpose: evaluate the therapeutic To effect of common salt (table or cooking salt) on umbilical granuloma in infants. tube feeding. He had hypotonia anddelayed global development so started early intervention at 5 months. Were been observed temperature Eliška Štefanová Poster Presentation fruits and vegetables. olds complained 11-year about absence of family mealtimes. Children reported taste and social motives as main reasons for drinking soft and energy drinks. Girls were more concerned about their body image. feeding difficulties, contraction of the small fingers joints and autism spectrum disorder. Currently, there are 28 casessyndrome of Schaaf-Yang P. J. Šafárik J. UniversityP. in Košice, Slovakia; [email protected] FINDINGS REGARDING NUTRITIONAL BEHAVIOUR: QUALITATIVE ANALYSIS. QUALITATIVE BEHAVIOUR: FINDINGS REGARDING NUTRITIONAL performed brain MIR that showed a thin corpus callosum, the aCGH was normal and genetic studies related to family dysautonomy and a panel preventive measures in this target group. Conclusion: Conclusion: which is associated with overweight and obesity during adultness. Among other important aspects belong inadequate consumption of fruits Conclusion: with a fundamental genetic counselling to the family. response (complete regression, no discharge, and healed with complete epithelialization) and no response (b) regression (no of umbilical should be focused both on children and their parents as role models in development of eating habits. single transverse palmar groove, syndactyly in both feets, sryptorchidism in the right side of the body. During the etiological investigation, he 1 delay in his development, including delay in the motor skills, in language development, with some features connected to autism. children wrote their opinions into working sheets. Data was processed by a qualitative content analysis. of the persistent drainage or moisture involving the umbilicus after the cord has dried and separated. If umbilical granuloma remains untreated, chemical cauterization with silver nitrate or copper sulphate, electrocauterization, cryocauterization, granuloma ligation, and surgical excision. clinically evident umbilical granuloma. Parents of these 50 infants were given instruction to treat their infants at home. The treatment consistedof application of common salt on the lesion twice washing a day, 30 min and later, repeating the procedure for 5 days. All infants were re- can be performed by parents at home. constriction and salience of metopic suture, micrognathia, distal arthrogryposis in both hands especially on the fourth and fifth fingers, right of arthrogryposis were normal. the At same time a Whole Exome Sequencing revealed (WES), truncated a mutation of the MAGEL2 gene, compatible withsyndrome, the Shaaf-Yang a mutation bearded by the Currently, father. the child has 3 years and 7 months of age, an overall drescribed in literature. The clinical complexity of this syndrome demands the monitoring and an early intervention from a multidisciplinary team, granuloma, and persistent umbilical discharge). evaluated after 1 week and 3 weeks to see the effect of common salt on umbilical granuloma. The effects were gradedexcellent as (a) Table 1: Table adolescence may prevent several chronic diseases. One of the most crucial aspects of unhealthy eating behaviour includes breakfast skipping, and vegetables, lack of family mealtimes, increased consumption of soft and energy drinks and concerns about body image. Unhealthy eating yearsand old) 15 attended sessions in classrooms where they discussed their opinions and attitudes regarding dietary habits. After debate, Abdullah Saleh Al Saleh THERAPEUTIC EFFECT OF COMMON SALT ON UMBILICAL GRANULOMA IN INFANTS GRANULOMA ON UMBILICAL THERAPEUTIC EFFECT OF COMMON SALT

Abstracts 1st, 2nd, 3rd and 4th groups, respectively. There was a significant difference between the 3rd and 4th groups and the other groups (p <0.05). (p groups other the and groups 4th and 3rd the between difference asignificant was There respectively. groups, 4th and 3rd 1st, 2nd, ALL DIARRHOEA AND VOMITINGINCHILDRENISNOTGASTROENTERITIS POSTER PRESENTATIONS POSTER

POSTER SESSION 2 SESSION POSTER and present with unusual signs and symptoms. and signs unusual with present and significantly. reduced has strains two these to due meningitis of 2015, incidence the 1st September Bfrom Men and 1990 in MenC against and-reach test and groups were compared among themselves. among compared were groups and test and-reach effect of performing Taekwondo on the general health status in children and adolescent. and children in status health general the on Taekwondo performing of effect of the infants in our cohort had received the vaccine. It is important to suspect MenW in infants and toddlers presenting with atypical symptoms gastroenteritis. acute of symptoms atypical with presenting toddlers and infants in MenW suspect to important is It vaccine. the received had cohort our in infants the of as babies so establish to protection herd for ayear over take will it vaccine, ACWY with immunised 14-18 being are Although olds year cohort. septicaemia MenW with children and adults Several infection. tract respiratory asevere or arthritis septic with present patients septicaemia, or meningitis of symptoms 5-10%) to than (13% Rather compared mortality and incidence the in increase an is there recently Europe, of outside Presentations demographic characteristics (p> 0.05). The sit-and-reach test means were 28.6 ± 6.3 cm, 30.8 ± 6.4 cm, 24.6 ± 5.8 cm and 23.6 ± 5.9 cm for the the for cm ±5.9 23.6 and cm 24.6 ±5.8 cm, ±6.4 30.8 cm, ±6.3 28.6 were means test sit-and-reach 0.05). The (p> characteristics demographic children were divided into 4 groups of 25 children in each group. Group 1 was the highest level of belt (black and red), Group 2 was better than than better 2was Group red), and (black belt of level highest the 1was Group group. each in children 25 of 4groups into divided were children 1 COMPARISON OFFLEXIBILITY OFCHILDRENTAEKWONDO ATHLETES INDIFFERENTBELT LEVELS rapidly deteriorated. Subsequently, was found to have meningitis due to Men W 135. 22 children tested positive for Neisseria meningitides meningitides Neisseria for positive tested children W135. 22 Men to due meningitis have to found was Subsequently, deteriorated. rapidly means were 146.1 ± 10 cm, 38.8 ± 8.6 kg and 17.9 ± 2.5 kg / m2, respectively. There was no significant difference between the groups in terms of of terms in groups the between difference significant no was 146.1 were There 17.9 kg and means ±8.6 ±10 38.8 respectively. cm, kg /m2, ±2.5 children. in agility and flexibility endurance, and strength muscular mid level (blue and green), Group 3 was the mid level (yellow) and Group 4 was the lowest level of belt (white). Flexibility was assessed with sit- with assessed was (white). Flexibility belt of level lowest the 4was Group and (yellow) level mid the 3was green), Group and (blue level mid Conclusion: Conclusion: present mainly with gastrointestinal symptoms but without the characteristic non-blanching rash and progress rapidly to death as in our patient patient our in as death to rapidly progress and rash non-blanching characteristic the without but symptoms gastrointestinal with mainly present survived. and illness insidious more 2had other the and died and rapidly deteriorated positive popularity in recent years. There are some studies that Taekwondo develops physical fitness parameters such as cardiovascular endurance, endurance, cardiovascular as such parameters fitness physical develops Taekwondo that studies some are There years. recent in popularity flexibility of lower extremity muscles was also increased with the increase of Taekwondo specific skills and performance. Because Taekwondo BecauseTaekwondo performance. and skills specific of Taekwondo increase the with increased also was muscles extremity lower of flexibility the vulnerable group will remain unprotected. It has been shown that the MenB vaccine Bexsero would protect against MenW strain. But none none But strain. MenW against protect would Bexsero vaccine MenB the that shown been has It unprotected. remain will group vulnerable the Results: fatal. progressively and atypical is which Wstrain to due meningitis of To awareness raise Purpose: Presentation Poster Presentation Poster Results: levels. belt different at Taekwondo perform who children of flexibility the compare to was study this of aim The Purpose: However, an alarming rise in a particularly deadly strain of group W disease is seen. Children under 14 are not immunised against this strain strain this against 14 immunised not under are Children seen. is Wdisease group of strain deadly aparticularly in rise However, alarming an [email protected] Kingdom; United Trust, Birmingham, foundation NHS Hospitals England of Heart Kamer Unal Eren Unal Kamer Lydia Baldwin, Muhammed Khan Muhammed Lydia Baldwin, We had 4 children present with acute diarrhoea and vomiting illness with mild to moderate fever for over 24 hrs and and 24 over hrs for fever moderate to mild with illness vomiting and diarrhoea acute with present 4children We had Methods: and Materials A total of 100 children, 50 girls and 50 boys, between the ages of 10 and 12 years participated in the study. The The study. the in 10 12 of participated and ages years the between boys, 50 and girls 50 100 of children, Atotal Methods: and Materials isolated from blood in 2 and CSF in the other 2. All 4 presented with diarrhoea and vomiting illness with fever. 2 patients with blood culture culture blood with fever. with 2patients illness vomiting and diarrhoea with 4presented All 2. other the in CSF 2and in blood from isolated is a discipline, especially dominant with foot techniques. Further studies should be examined flexibility in with different age groups, also the the also groups, age different with in flexibility examined be should studies Further techniques. foot with dominant especially adiscipline, is Introduction: Introduction: 1 217ID: /PO2: / PO2: 2 /PO2: 283 ID: between Jan 2015 to July 2017, 15 were MenB, 1 MenC, 4 Men W135, 2 not typed. All were sensitive to cephalosporin. to sensitive were All 2015 2017, Jan July to W135, typed. 4Men 2not between 1MenC, 15 MenB, were █ Bezmialem Vakıf University, Turkey; Vakıf University, Bezmialem PO2: POSTER PRESENTATIONS: 2 SESSION █ Time: PO2: POSTER PRESENTATIONS: 2 SESSION The mean age of the children participating in the study was found to be 11.0 ± 0.8 years. The height, weight and Body Mass Index Index Mass Body and weight 11.0 be to height, found The was years. study ±0.8 the in participating children the of age mean The All 4 patients were male and aged around 13.5 months, all males and fully immunised but none had received Bexsero. Men W135 Men Bexsero. received had none but immunised fully and males all 13.5 months, around aged and male were 4patients All 20 9 Friday, 08/Dec/2017:1:30Pm-2:30pm•Location:Mancini 3A t h Though MenW has caused only a small proportion of meningococcal infections worldwide and tends to be more prevalent prevalent more be to tends and worldwide infections meningococcal of proportion asmall only caused has MenW Though Taekwondo is a suitable martial art in the development of physical fitness in children. According to the results of the study, the the study, the of results the to According children. in fitness physical of development the in art martial asuitable is Taekwondo

E Taekwondo is a martial art including hand and foot techniques and could perform in all age groups. Taekwondo has gained in in gained has Taekwondo groups. age all in perform could and techniques foot and hand including art amartial is Taekwondo Most meningococcal disease in the UK has been due to group B (MenB) and group C (MenC). Since the introduction of vaccine vaccine of introduction the C(MenC).Since group and B(MenB) group to due been has UK the in disease meningococcal Most D I T 1 I O 7 1 N , Gul Sener , Gul Topics: Topics: Sports Medicine, Obesity & Physical Activity &Physical Obesity Medicine, Sports General Pediatrics, Infectious Diseases &Vaccines Diseases Infectious Pediatrics, General 2 , Chetana Kallappa , Chetana CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 2 Hacettepe University, Turkey; [email protected] University, Hacettepe

POSTER SESSION 2 SESSION POSTER 99

Abstracts 100 54,9 Females 27,3 % 44,0 19,3 55.0 Males 25,2 25,2 41,9 18,2 POSTER SESSION 2 55,2 Bullies 21,9 26,2 42,7 16,8 Total

p< .036 n.s. n.s. n.s. n.s. Chi-Square Tests

Yalova University, [email protected] Turkey; 3 3 60,0 Females (N=275) 71,3 41,1 49,5 41.8

POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE 52,3 Males 66,3 (N=258) 74,8 49,2 48,1 , Pınar Kütük Yılmaz 2 Ankara University Turkey; Adolescent Mental Health Mental Adolescent General Pediatrics, Infectious Diseases & Vaccines 2

Topics: Topics: , Francisco Ribeiro-Mourão, Francisca Martins, Ariana Teles, Ana Vaz, Sandrina Martins 50.8 63.4 (N=543) % 73.1 Victims 44.9 44.6 Total N 7 , Metin Pişkin O I 1 1 T I D Evidence on treatment of cat scratch disease is missing (CSD) and the clinical approach may be a challenge. Bullying is repetitive physical, verbal, social, or electronic aggressive actions by a person or group against a person. It is stated E

Regional lymphadenopathy is the hallmark of CSD and is generally self-limiting. Abscess formation is rare. In this clinical The results indicate that bullying is a substantial problem for adolescents staying in orphanage It appears houses, in Turkey. that h t 9 20 Frequency of Adolescents Identified as “Victims” and “Bullies” PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: isolation Harming Porperty Harming Physical Rumor spreading Rumor Verbal Victimization Types ofTypes Hacettepe University Turkey; bully, victim,bully, bully-victim, and the neutral rates were calculated both in general and in terms of gender. Gender analysis is calculated separately Introduction: ID: 291 / PO2: 3 Introduction: initially treated with oral amoxycillin/clavulanic acid for 48 hours with no improvement. physical At examination, a 4 cm tender tumefaction in leftinguinal area and erythema of the overlying skin were noted. An ultrasound of the area revealed a lymphadenopathy measuring cm X 1.5 3.7 intravenous antibiotics: amoxycillin/clavulanic acid and azithromycin. During the hospitalization, the diagnosis of CSD was confirmed. A 5-day ID: 251 / PO2: 4 lymphadenopathy in children with These CSD. are even rarer when considering immunocompetent patients. A more virulent pathogenetic Materials and Methods: The sample consisted of 543 adolescents females). The males, ages (48,4% of 51,6% participants varied between Bartonella sp. was registered. Patient improved with full recovery. Results: tumefaction in left inguinal area of 2 weeks’ duration. No other symptoms or events were reported; the family had 2 kittens at home. She was Poster Presentation that there is an increase in mental and physical health problems in people who are bullied or exposed. Children who are exposed to bullying Purpose: The main objective of this research is to assess thefrequency and types of victim/bully behavior among adolescents staying in the cause of progression of the disease. Poster Presentation for different types of bullying dimensions. Mann was Whitney used to analyze U-Test the distribution of different types of bullying by sex. A fluid, which makes the Bartonella Henselae the most probable causative agent. There are only a few case reports of abscess-forming BULLYING AMONG ADOLESCENTS LIVING IN ORPHANAGES IN TURKEY ADOLESCENTS LIVING IN ORPHANAGES AMONG BULLYING victimized them while in the Bullying Scale they were asked to answer how often they did bullying behaviors. The sub-dimensions Physical, are: property) are also examined in relation to the sex. variant is a possible explanation for these cases. Like our clinical case, to the best of our knowledge in none of the reported cases it is known Case Report: An eleven-year-old girl, without relevant pre-existing conditions, presented to the Emergency Department with (ED) a painful Conclusion: with inflammatory characteristics. CSDwas suspected and serologic testing for Bartonella was sp. performed.Patient started treatment with Conclusion: Ultrasound evaluation confirmed an abscess(4.5 X 3.5 X 3 withcm) a fistulous tract for the skin. She was admitted for drainage and completed statistical significance level 0.05of was taken. Unidade Local de Saúde do Alto Minho, Portugal; [email protected] signs. An ultrasound showed slight increase in lymphadenopathies’ Patient cm). was admitted X 1.7 size (4.3 to the hospital and treated with CAT SCRATCH DISEASE: BEYOND A LYMPHADENOPATHY A DISEASE: BEYOND SCRATCH CAT 1 (chi[sub 2] (d.f. 1) =3,56,(chi[sub 1) 2] (d.f. p< .036 data. The scale consists of “Victim Scale” and “Bully Scale”. In the Victimization Scale, participants were asked to answer how often their mates oral azithromycin mg/kg/day 10 and ibuprofen. Onthe third day of treatment, she returned with worsening of the tumefaction and inflammatory course of azithromycin was completed, with slight reduction of lymphadenopathy and the cm), patient X 1.5 (3.4 was discharged. About days 10 orphanage houses, Different regions in 12 of Turkey. types of bullying behaviors (physical, verbal, isolation, rumor spreading, and harming case, a bacterial superinfection of the lymph node could be the aetiology of the abscess. no bacteria However, were identified in the abscess orphanage houses don’t always effectively deal with bullying problems among adolescents. an 8-day course of cefazolin. No organisms grew on the abscess fluid and a sustained increase of the immunoglobulin M and G response to after the diagnosis, the patient developed a draining sinus tract and presented with a larger tumefaction with fluctuance in left inguinal area. aremore likely to avoid school than those who do not, and psychosomatic problems are more likely to have legislative and low academic achievement. Therefore, bullying isan important public health problem in schools. Vera Lúcia Gonçalves Verbal, Isolation, Rumor spreading, Harming property, Sexual bullying. In the analysis, descriptive statistics were calculated first. Subsequently, Yasemin Özkan 11-18 (X = 15.05, SD = 1.71). “PeerBullying Identification (X SD = 1.71). = 15.05, Scale 11-18 –Adolescent Form” developed Pişkinby (2007)andAyaş was used to collect

Abstracts The majority said that the most common causes were foetal brain damage, malformations of the brain and brain tumour. The percentage percentage The tumour. brain and brain the of malformations damage, brain foetal were causes common most the that said majority The TOWARDS STUDENTS WITHEPILEPSY Agnieszka Malkowska-Szkutnik American hematologist W. B. Bean, (1909-1989) as a kind variant of blue nevus syndrome: congenital multiple cavernous hemangioma of the the of hemangioma cavernous multiple congenital syndrome: nevus blue of (1909-1989) variant W. Bean, akind B. as hematologist American assistance in the event of seizure; beliefs about teaching children with epilepsy; 2) for teachers who are currently teaching or have taught taught have or teaching currently are who 2) teachers for epilepsy; with children teaching about beliefs seizure; of event the in assistance epilepsy; b) preparedness of teachers to work with these students, and the difficulties with working with this group of students and expected expected and students of group this with working with difficulties the and students, these with work to teachers of b) preparedness epilepsy; extremities (PL 28%, CzR 22%) was substantial. Among the class teachers teaching students with epilepsy, it was considered difficult/stressful difficult/stressful considered was it epilepsy, with students teaching teachers class the Among substantial. CzR 22%) was (PL 28%, extremities of surgical treatment, mortality. treatment, surgical of on: preparedness to work with students with epilepsy; knowledge/skills in this field; level of knowledge about epilepsy, skills for providing providing for skills epilepsy, about knowledge of level field; this in knowledge/skills epilepsy; with students with work to on: preparedness questions including 1) teachers, used: was all for parts two of consisted Aquestionnaire teachers. education physical and teachers class - groups two in conducted was study The 1277 of teachers. (CzR) sample 2016 in the on Republic Czech the (PL) and Poland in collected were Data Programme. Erasmus+ the of Agency Polish -the System Education the of Development the for Foundation the with cooperation it. from suffer age this at 1% population of around that show Estimates children. [email protected] Ireland; Epidemiology; of Department Ireland, in Surgeons of of Mother and Child Foundation, Poland; Poland; Foundation, Child and Mother of of skin cavernous hemangiomas and mucosal lesions of the gastrointestinal tract, called Bean syndrome. This syndrome was described by by described was syndrome This syndrome. Bean called tract, gastrointestinal the of lesions mucosal and hemangiomas cavernous skin of patients. these in damage neurological for arisk indicate parameters these whether determine to order in levels glucose of teachers who chose the wrong procedure in the case of seizure: to insert an object into the mouth (PL 35%, CzR 46%) and to hold the the hold to CzR 46%) and (PL 35%, mouth the into object an insert to seizure: of case the in procedure wrong the chose who teachers of or elevated C-reactive protein levels (>5mg/l). and absence of meningitis as evident from normal CSF white blood cell count and negative negative and count cell blood white CSF normal from evident as meningitis of absence and (>5mg/l). levels protein C-reactive elevated or different from neonates with normal CRP (0.98 (SD 0.4) (n=22). CSF-glucose levels where available were in infants with sepsis 2.68 mmol/l (SD (SD mmol/l 2.68 sepsis with infants in were available where levels (SD (0.98 0.4) CRP (n=22). CSF-glucose normal with neonates from different 1 skin and gastrointestinal tract. Bean’s syndrome is a rare and we did not meet in the available literature data on the disease outcome, efficacy efficacy outcome, disease the on data literature available the in meet not did we and arare is syndrome Bean’s tract. gastrointestinal and skin stigmatization and isolation the extent possible. extent the isolation and stigmatization students with epilepsy in the past 10 years. past the in epilepsy with students CHILDREN WITHEPILEPSY -KNOWLEDGE AND BELIEFSOFTEACHERSINPOLAND AND THECZECHREPUBLIC CEREBROSPINAL FLUIDPROTEIN AND GLUCOSELEVELSINNEONATES WITHSEPSISWITHOUTMENINGITIS CLINICAL CASEOFBEAN’SSYNDROME Scientific center of pediatrics and children surgery, Kazakhstan; [email protected] Kazakhstan; surgery, children and pediatrics of center Scientific meningitis have previously been associated with white matter damage on magnetic resonance imaging. resonance magnetic on damage matter white with associated been previously have meningitis without sepsis with neonates of CSF the in levels interleukin-1 Increased meningitis. bacterial with associated sepsis in outcome neurological meningitis. Conclusion: was between 26+6 and 42+3 weeks. CSF protein levels were with 0.84g/l (SD 0.23) in neonates with fever (n=19) not significantly different different (n=19) fever with significantly not neonates in (SD 0.23) 0.84g/l with were levels protein CSF weeks. 42+3 and 26+6 between was Conclusion: prepared to talk with their students who witnessed seizure at school. Almost all teachers said epilepsy could occur at all stages of life (92%). life of stages all at occur could epilepsy said teachers all Almost school. at seizure witnessed who students their with talk to prepared polymerase chain reaction and CSF culture result with neonates who had a CSF obtained without fever or CRP elevation CRP or fever without obtained aCSF had who neonates with result culture CSF and reaction chain polymerase forms of assistance to overcome possible issues. possible overcome to assistance of forms Presentation Poster Results: with students teaching towards beliefs their and epilepsy about teachers of a) knowledge assess: to were study this of aims The Purpose: from neonates without with 0.92g/l (SD 0.39) (n=164) and in neonates with suspected sepsis and elevated CRP level (n=161) not significantly (n=161) level CRP elevated and significantly not sepsis suspected with (SD (n=164) 0.39) neonates in 0.92g/l and with without neonates from Presentation Poster We investigated whether neonatal sepsis in the absence of meningitis is associated with elevated CSF protein and reduced CSF CSF reduced and protein CSF elevated with associated is meningitis of absence the in sepsis neonatal whether We investigated Purpose: Results: Luton & Dunstable University Hospital NHS Foundation Trust, United Kingdom; [email protected] Kingdom; Trust, United Foundation NHS Hospital University &Dunstable Luton Presentation Poster This study was a part of the project “EPISCHOOL – “Let`s overcome barriers together!” It has been realised in in realised been has It together!” barriers –“Let`s overcome “EPISCHOOL project the of apart was study This Methods: and Material Minira Bulegenova Minira Noureldein Mona Retrospective case control study comparing CSF results of neonates with fever (temperature >38.0 degrees Celsius) Celsius) degrees >38.0 (temperature fever with neonates of results CSF comparing study control case Retrospective Methods: and Materials ID: 116ID: 7 /PO2: Introduction: Introduction: Introduction: 5 /PO2: 203 ID: is no meningitis. If there is a low CSF glucose or elevated CSF protein this should therefore alert the clinician to the possibility of additional additional of possibility the to clinician the alert therefore should this protein CSF elevated or glucose CSF alow is there If meningitis. no is 0.40) (SD 2.58 (n=26). with without infants from different (n=151)0.85) significantly not and / PO2: 6 /PO2: 264 ID: better cooperation between teachers and parents, training for teachers. for training parents, and teachers between cooperation better epilepsy, of awareness public increasing support: of forms following the indicted teachers 21% surveyed and The CzR. PL teachers -32% by University of Warsaw, Faculty of Education, Department of Biomedical Foundations of Development and Sexology, Poland; Poland; Sexology, and Development of Foundations Biomedical of Department Education, of Faculty Warsaw, of University PO2: POSTER PRESENTATIONS: 2 SESSION The majority of teachers said that they knew little or very little about epilepsy. 44% of Polish and 29% of Czech teachers did not feel feel not did teachers Czech of 29% and Polish of 44% epilepsy. about little very or little knew they that said teachers of majority The We included data of a total of 183 neonates systematically for a 2-year period. The gestational age at the time of the lumbar puncture puncture lumbar the of time the at age gestational The period. a2-year for systematically 183 of neonates atotal of data We included 20 9 t h Teachers with the knowledge and ability to work whit this group should help them studying, strengthen self-esteem and prevent prevent and self-esteem strengthen studying, them help should group this whit work to ability and knowledge the with Teachers CSF protein and glucose levels are not affected by a systemic inflammatory response syndrome, as seen in sepsis, if there there if sepsis, in seen as syndrome, response inflammatory asystemic by affected not are levels glucose and protein CSF

E Epilepsy is one of the most common neurological diseases in children and adolescents. It occurs particularly in school-aged school-aged in particularly occurs It adolescents. and children in diseases neurological common most the of one is Epilepsy Hemangioma is a benign tumor, refers to vascular malformations that occur during embryogenesis. There is a combination acombination is There embryogenesis. during occur that malformations vascular to tumor, refers abenign is Hemangioma adverse with associated been previously have levels glucose CSF reduced and protein (CSF) fluid cerebrospinal Increased D I T 1 I O 7 N , Roxana Mardare, Jack Pickard, Hoi Shing, Michael Eisenhut Michael Shing, Hoi Pickard, Jack Mardare, , Roxana , Dilyara Kachurina, Badim Litosh, Gulnara Kaukenbaeva Gulnara Litosh, Badim Kachurina, , Dilyara Topics: Topics: Topics: General Pediatrics, Rare Diseases Rare Pediatrics, General Infectious Diseases & Vaccines, NICU &Vaccines, Diseases Infectious Neurology, Adolescent Health Communication Health Adolescent Neurology, 1 , Dorota Kleszczewska , Dorota CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 3 Palacky University Olomouc, Faculty of Physical Culture, the Czech Republic; Republic; Czech the Culture, Physical of Faculty Olomouc, University Palacky 2 , Ferdinand Salonna , Ferdinand

3 , Jakub Gajewski , Jakub POSTER SESSION 2 SESSION POSTER 4 4 Royal College College Royal 2 The Institute Institute The 101

Abstracts 102 POSTER SESSION 2

, Dmitriy Bondarenko, Daniyar Kusainov, Minira Bulegenova POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE General Pediatrics, Rare Diseases General Pediatrics Topics: Topics: N , Natan Rosenfeld, Elchanan Fried, Rivka Brooks, Naama Holzer 7 O I 1 T I D Hemolitic-uremic syndrom is (HUS) a chronic disease requiring lifelong observation and treatment. The target organ of We aim We to implement in time, follow-up of medical recommendations for a chronic, autosomal, recessive, genetic, complicated E

h t 9 20 Decision of the consilium was as follows: the final diagnosis “hemolytic-uremic syndrome”. The consilium recommended the PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: backgroundis syndrome of disseminated coagulation, which occurs mainly in children up to 5years. As the symptoms caused by the syndrome but then relapses have repeated. The active surgical interventions in the neonatal period were not appropriate. months In 1.5 positive dynamics was ID: / PO2: 137 9 health condition progressively worsened due to intoxication, which caused the development of multiple organ failure, neurologic symptoms,hemorrhagic, hepatorenal syndrome, intestinal paresis symptoms and deep metabolic disorders. On March the child’s 31th health condition Introduction: ischemia with a multiple organ dysfunction. In pediatric practice the most likely complication of HUS, developed on the infectious process Introduction: is no specific treatment for this disease, the FD patients need to be treated symptomatically for each organ system, or in combination.We used ID: 206 / PO2: 8 hemoglobin (60 g/l), platelets For the health (18x109/l). condition stabilization blood transfusions and transfusion of platelet concentrate have been limbs, face. Hemangiomas of a pink color, with a purple tint in the middle, a different diameter from 0.2-0.5-0.8-1.0 sm, turning pale when pressed. Decision: Familial Dysautonomia Center, Pediatric* and Internal** Department, Hadassah Medical Center, Hebrew University Medical School, Poster Presentation Purpose: evaluate the efficiency To of this computerized program to enable the patients to perform the required tests and given medical results ofantibiotical sensitivity), - Immunoglobulins intravenous,- In cases of unstable hemodynamics: noradrenaline, of titration the computer program of Microsoft’s “Outlook,” which, by a specific sound, reminded us to tell each FD patient to perform thevarious tests or Hadassah Medical Jerusalem, Center, Israel; [email protected] for further treatment to the profile department. Poster Presentation following intensive medical measures: - peritoneal dialysis, - Plasmotransfusion, - hemotransfusions the hospital, the child had repeated gastrointestinal bleeding in the form of hematemesis, melenaand as a result the pronounced decrease in formations of the left hip, gluteal, inguinal and left lumbar region. Vascular malformation? Fibro-esophagogastroduodenoscopy: hemangiomatous Performing of combined treatment with peritoneal dialysis has been resulted in the child’s condition improved, the patient has been transferred FAMILIAL DYSAUTONOMIA FAMILIAL procedures, radiation therapy is available in older ages. The prognosis is unfavorable protruding above the surrounding tissue, turn pale when pressed. Gastrointestinal bleeding occurred in the maternity hospital, and as the result Gulshat Alimhanova,Shekenova Anar (washed red blood cells), - prednisolone ( 2 mg - heparin / kg), (500ED/lphysiognil 2.27%), - antibacterial therapy (according to the performed. The following treatment was prescribed:prednisolone mg every (6 / day) / kg other day + beta-blocker propranolol mg (3 / day). / kg Clinical Case: In connection with above mentioned, it was interesting to analyze a clinical case with a similar picture of the disease in a child Channa Maayan Channa Clinical Case: present We a clinical case of a child with the Bin’s syndrome. Child days old, A, 12 was admitted to our center with a preliminary much, hepatic enzymes figuresexceeded the referencevalues 3-3.5 times as much, indicating the presence of hepatocytes’s cytolysis. PCR medical recommendations, at the specific dates required, so they could receive the appropriate treatment in time. microangiopathic thrombus formation is the kidneys, generalization however, of TMA is possible leading to the development of multi-organ neuronal development results in defective neuro-regulation of multiple organ systems. Most of the body’s organ systems are affected. As there Scientific center of pediatrics and children surgery, Kazakhstan; [email protected] recommendations. St. Localis: Lesion of the soft tissue palpated in the upper third of the thigh. The skin is bluish or purple color, painless. There are areas of the seal skin at the age of 1 month old, after what the child was directedto the children’s city clinical infectious diseases hospital. Instrumental-diagnosticstudies confirmed the hepatobiliary syndrome.Total bilirubin exceeded the reference norms ten times as much, direct bilirubin – 30 times as studies on intrauterine infection: CMV in the mother’s 06.01.2017 CMV in the milk urine – positive, of the child) 14.03.17 - positive. The child’s Gastrointestinal bleeding confined for a while that resulted in insugnificant platelet increase. Improvement of the condition was observed for a week, Impairment of platelet aggregation (reduced aggregationwith adrenaline) ( N :50-80%). - 12,5% – normal. ECG, EEG Chest Small-cystic MRI: X-ray, COMPUTERIZED FOLLOW-UP SYSTEM FOR MEDICAL RECOMMENDATIONS IN CHRONIC DISEASES SUCH AS IN CHRONIC DISEASES SUCH RECOMMENDATIONS MEDICAL SYSTEM FOR COMPUTERIZED FOLLOW-UP CLINICAL CASE: CYTOMEGALOVIRUS INFECTION COMPLICATED BY THE DEVELOPMENT OF THE HEMOLITIC- BY COMPLICATED INFECTION CASE: CYTOMEGALOVIRUS CLINICAL sedimentation ratio-2 mm/h. Biochemistry - all parameters within reference norms. Coagulation: APTT – 37 min.,PTI – 85%, Fibrinogen – 2.5 g/l. UREMIC SYNDROM. deteriorated because of severe hyperthermia (39,90C), diarrhea, anemia, thrombocytopenia, anuria. of disseminated coagulation are prevailing, the identification of the underlying infectious disease sometimes does not seem possible. of the firstyear of Patientlife. was R., charged to Scientific center of pediatrics at the age3 of months. Mother noted the marked jaundice of the disease known as Familial Dysautonomia FD is characterized (FD). by extensive autonomic and sensory dysfunction. Abnormal autonomic delivery. The girl was born with a weight - 3694 Apgar g, 7-8 score. Visually: pale skin. Multiple hemangiomas are defined on the upper, lower diagnosis: “congenital malformations. Kasabach-Merritt syndrome. Congenital hemangioma. Severe post-hemorrhagic anemia, thrombocytopenia”. of the stomachand the jejunum. Colonofibroscopy - Hemangioma of the rectum and lower colon. Intestinal bleeding. During the time spent in observed. After stabilization of clinical and laboratory indicators the girl was discharged home. Currently child is an outpatientof residence. surgeon at the According place to the literature the main treatment of disseminated hemangiomatosis is combination of conservative treatment and surgical anemia - (hemoglobin-97g/l), thrombocytopenia 9/l).Blood x10 (49 test: RBC- 9/l, 9/l, 2.9 Hb-77 x10 x10 g/l, Ht – 22%, WBC-21 9/l, PLT-81.0 x10 Anamnesis: heredity is not burdened. First pregnancy, first childbirth. At Mom: the first trimester mom had respiratory viral infection. Urgent Jerusalem, Israel

Abstracts 1.75g/kg body weight (max 75g). Random blood sugar and insulin was done 2hours later. Height, weight, WC and fat mass (FM) was measured measured was (FM) mass fat WC and weight, later. Height, 2hours done was insulin and sugar blood 75g). (max Random weight 1.75g/kg body glucose anhydrous with done was OGTT Standard insulin. and glucose blood fasting profile, lipid for drawn was blood fast, 12hour overnight João, E.P.E;João, VAI(1.05±0.8), BAI(25.64±4.9). Percentage body FM showed significant association with VAI, BAI, WHtR, WHR, WC, BMI. WC and BMI BMI and WC BMI. WC, WHR, WHtR, with BAI, VAI, association significant showed FM body VAI(1.05±0.8), Percentage BAI(25.64±4.9). alterations. At 3 years and 10 months, she presented choreoathetosis (specially in superior members) with important dysmetria. At this time, time, At this dysmetria. important with members) superior in (specially choreoathetosis presented she 10 and months, At 3years alterations. The therapy. speech and psychomotricity physiotherapy, including stimulation, multimodal had She 60. of quotient intelligence aglobal and Vithanage Pujitha Wickramasinghe appointment, date of next clinic appointment, the type of clinical order, the type of tests, or recommendations (e.g. blood tests, urine tests, Xray, tests, urine tests, (e.g. blood recommendations or tests, of type the order, clinical of type the appointment, clinic next of date appointment, are used for screening for obesity related metabolic risk. However none of them take metabolic parameters for its calculation. Visceral Adiposity Adiposity Visceral calculation. its for parameters metabolic take them of none However risk. metabolic related obesity for screening for used are association with all metabolic parameters but FBS and BAI showed also showed good association with all but LDC-C. WHR did not show a a show not did WHR LDC-C. but all with association good showed also showed BAI and FBS but parameters metabolic all with association (thin lips, low implantation of the ears), a trunk ataxia, including in seated position and an unstable broad- based gait, needing support. At 31 support. needing gait, based broad- unstable an and position seated in including ataxia, ears), atrunk the of implantation low lips, (thin cerebral MRI showed type I Chiari malformation, with no other anomalies. She performed an etiologic study regarding ataxia that revealed no no revealed that ataxia regarding study etiologic an performed She anomalies. other no with malformation, IChiari type showed MRI cerebral other siblings, or with work. This program enables the patient to deliver the results to the physician, so that appropriate treatment can be given given be can treatment appropriate that so physician, the to results the deliver to patient the enables program This work. with or siblings, other with itself, disease complex the with either busy very usually is him, of care takes who family the or patient, The diseases. chronic complicated computerized follow-up program; and over another year, without the use of this program. The information inserted was: date of the clinic clinic the of was: date inserted information The program. this of use the year, without another over and program; follow-up computerized composition in 5-15year old school children in Colombo district of Sri Lanka. Sri of district Colombo in children 5-15year in school old composition than rather adiposity visceral with associated is risk disease the of most that fact the to due be could This risk. (NCD) disease communicable cutoff, 32(3.2%) were obese and 90(9.7%) were overweight. The mean±SD values of triglyceride(0.870.39mmol/L), HDL-c (1.2±0.41mmol/L), triglyceride(0.870.39mmol/L), of values mean±SD The 90(9.7%) overweight. and were obese were 32(3.2%) cutoff, 1 1 significate in motor fields). The child also had a congenital hypothyroidism medicated with levotiroxin. On physical exam, she had peculiar face face peculiar had she exam, physical On levotiroxin. with medicated hypothyroidism congenital had a also child The fields). motor in significate In her last formal evaluation with Ruth Griffiths developmental scales she had a global intelligence quotient of 75 (delay in language and and language in of 75 (delay quotient intelligence global a had she scales developmental Griffiths Ruth with evaluation formal last her In COREOATHETOSIS AND CONGENITAL HYPOTHYROIDISM mutation in NKX-2 was detected corroborating the hypothesis. The child began tetrabenazine for the chorea and vigilance of lung symptoms. symptoms. lung of vigilance and chorea the for tetrabenazine began child The hypothesis. the corroborating detected was NKX-2 in mutation months of age, she did a formal psychometric evaluation with Ruth Griffiths developmental scales revealing a developmental age of 18 months of age months 18 developmental a revealing scales developmental Griffiths Ruth with evaluation psychometric aformal did she age, of months significant association with the metabolic parameters. metabolic the with association significant strong showed WHtR OGTT). and VAI hour at 2 RBS and FBS (TG,LDL-C, HDL, parameters metabolic all with association significant showed Index (VAI) is a new index developed using BMI, waist circumference (WC), Triglycerid (TG) and HDL-c (TG) and (WC), Triglycerid circumference waist BMI, using developed index (VAI) anew is Index South Asian populations are known to have high fat content of the body for any given BMI value compared to many other ethnic groups. This This groups. ethnic other many to compared value BMI given any for body the of content fat high have to known are populations Asian South Conclusion: year without this program, showed a 62% increase of efficiency using the computerized program. computerized the using efficiency of increase a62% showed program, this without year A 27-month child was referred to Neurodevelopmental consultation, due to global delay on psychomotor development (more (more development psychomotor on delay global to due consultation, Neurodevelopmental to referred was child A27-month Study: Case using BIA. Blood pressure was measured after 10 min rest. Insulin resistance assessed by HOMA-IR. by assessed resistance Insulin 10 rest. min after measured was pressure Blood BIA. using whole body adiposity. Different anthropometric indices such as waist hip ratio (WHR), waist to height ratio (WHtR), Body Adiposity Index(BAI) Index(BAI) Adiposity Body (WHtR), ratio height to (WHR), waist ratio hip waist as such indices anthropometric Different adiposity. body whole Conclusion: CT, medical specialist, physiotherapy), implementation date of the clinical recommendation and the audio-sound reminder for this date. this for reminder audio-sound the and recommendation clinical the of date implementation physiotherapy), specialist, CT, medical pulmonary manifestations, or when there is a non-progressive chorea presenting in early childhood. early in presenting chorea anon-progressive is there when or manifestations, pulmonary Conclusion: FROM AN URBAN AREA OFSRILANKA. DIFFERENT ADIPOSITY INDICES AND ITSRELATION TO METABOLIC ABNORMALITIES IN5-15 YEAR OLDCHILDREN Presentation Poster Presentation Poster Results: The aim of this study is to examine the relationship between different obesity-related indices and biochemical parameters and body body and parameters biochemical and indices obesity-related different between relationship the examine to is study this of aim The Purpose: Hospitalar São João, E.P.E; João, São [email protected] Hospitalar Results: Dilshan Lourenço Lara However, further studies are needed to develop VAI and BAI cutoff values to detect presence of adverse metabolic profiles. metabolic adverse of presence detect to values VAI cutoff BAI and develop to needed are studies However, further Medicine, University of Colombo, Sri Lanka.; [email protected] Lanka.; Sri Colombo, of University Medicine, Twenty-five FD medical records were randomly chosen to be evaluated and compared over one year with the the with year one over compared and be evaluated to chosen randomly were records medical FD Twenty-five Methods: and Materials A cross sectional descriptive study, using two-stage probability proportionate cluster-sampling technique. After a a After technique. cluster-sampling proportionate probability two-stage using study, descriptive sectional Across Methods: and Materials locomotor). The suspicion of a perturbation related to NKX2-1 must be raised when there is a congenital hypothyroidism with neurologic or or neurologic with hypothyroidism acongenital is there when raised be must NKX2-1 to related aperturbation of suspicion The locomotor). lung and thyroid involvement and in 30% there is only involvement of brain and thyroid. Despite chorea being a classical and early sign, the the sign, early and aclassical being chorea Despite thyroid. and brain of involvement only is there 30% in and involvement thyroid and lung / PO2: 11 /PO2: 248 ID: in time. This also inspires in the patient, confidence in his physician, knowing that the latter cares about his medical condition. medical his about cares latter the that knowing physician, his in confidence patient, the in inspires also This time. in initial neurologic manifestations can be various, like hypotonia, dystonia, dysarthria and ataxia. and dysarthria dystonia, hypotonia, like various, be can manifestations neurologic initial Introduction: / PO2: 10 /PO2: 229 ID: Introduction: has lead to the difficulty in using internationally available anthropometric cutoff to detect adverse fat content associated with increased non- increased with associated content fat adverse detect to cutoff anthropometric available internationally using in difficulty the to lead has before the hypothesis of coreoathetosis and congenital hypothyroidism with or without lung affection the specific genetic test is performed. A performed. is test genetic specific the affection lung without or with hypothyroidism congenital and coreoathetosis of hypothesis the before Department of Paediatrics, Faculty of Medicine, University of Colombo, Sri Lanka.; Lanka.; Sri Colombo, of University Medicine, of Faculty Paediatrics, of Department Hospital Pediátrico Integrado, Centro Hospitalar de São João, Portugal; Portugal; João, São de Hospitalar Centro Integrado, Pediátrico Hospital PO2: POSTER PRESENTATIONS: 2 SESSION 1 A comparison of the test results and the clinical recommendations, of the year using the computerized follow-up program, with the the with program, follow-up computerized the using year the of recommendations, clinical the and results test the of Acomparison Data from 920 children (boys 542) were collected. The mean±SD age of the study group was 10.2±2.7years. According to IOTF-BMI IOTF-BMI to According 10.2±2.7years. was group study the of age mean±SD The collected. were 542) (boys children 920 from Data , Buddhini SDissanayake , Buddhini 20 9 t h It is essential for the diagnosis, the clinical progression of the case and the multidisciplinary approach. multidisciplinary the and case the of progression clinical the diagnosis, the for essential is It This program was proved to be a simple and efficient way to follow up chronic FD patients. This model can be suitable for all all for suitable be can model This patients. FD chronic up follow to way efficient and asimple be to proved was program This Results show that WC, BMI, VAI, BAI and WHtR can be used in the assessment of obesity related metabolic abnormalities. abnormalities. metabolic related obesity of assessment the in used be can VAI, WHtR WC, BMI, and BAI that show Results 3

E Unidade de Neurologia Pediátrica, Centro Hospitalar São João, E.P.E.; João, São Hospitalar Centro Pediátrica, Neurologia de Unidade Obesity related metabolic abnormalities occur from a very young age and it is directly related to the fat content of the body. body. the of content fat the to related directly is it and age young avery from occur abnormalities metabolic related Obesity The perturbations related to NKX2-1 are rare and due to autossomal dominant transmission. In 50% of cases, there is brain, brain, is there cases, of 50% In transmission. dominant autossomal to due and rare are NKX2-1 to related perturbations The D I T 1 2 I Ana Reis eMelo Reis , Ana O 7 N Topics: Topics: Obesity & Physical Activity &Physical Obesity Infant Development, Neurology Development, Infant 1 , Daniel Gonçalves , Daniel 1 CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 1 , Carukshi Arambepola 2 , Mafalda Sampaio , Mafalda 2 , Priyantha Bandara

2 Unidade de Neurodesenvolvimento, Centro Hospitalar São São Hospitalar Centro Neurodesenvolvimento, de Unidade 3 , Cintia Correia , Cintia 2 Department of Community Medicine,Faculty of of Medicine,Faculty Community of Department 1 4 , Mithila Abeysekera Unidade de Endocrinologia Pediátrica, Centro Centro Pediátrica, Endocrinologia de Unidade POSTER SESSION 2 SESSION POSTER 4 , Micaela Guardiano , Micaela 1 , Suran Kuruppu Suran , 2 1 , Prasanna , Prasanna 103

Abstracts 104 , Alnura 3 , , Adel Elsharkawy 3 2 , , Anar Samedi 3 , Joana Carvalho 2 POSTER SESSION 2 Centro Hospitalar de Trás-os-Montes e Alto Douro, 2 University of Calgary, Calgary,Canada; veronica. 3 , , Nillifer Hasanova

1,2 , Ana Margarida Costa 2 , A Stang, 1,2 , Paulo Santos 2 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE Alberta Children Hospital, Calgary, Canada; 2 , , J Thull-Freedman Infectious Diseases & Vaccines, Management General Pediatrics, Adolescent Wellbeing Emergency Pediatrics Emergency 1,2 , Cristina Baptista 1 Topics: Topics: Topics: N , Nina Dwi Putri, Hindra Irawan Satari 7 O I 1 T I D Tetanus is a serious Tetanus bacterial infection caused by Clostridium tetani. Clostridium tetani produces a toxin that is taken up into Coarctation of aorta is a common (CoAo) pathology, representing 5-8% of congenital heart diseases. It may occur isolated or Intussusception is one (ITS) of the most common causes of the bowel obstruction during infancy and early childhood. It is an E

Analgesia/ sedation for ITS reduction currently is not a standard of care. are We planning to start survey focused on pain Enteral baclofen may be considered as a additional anti-spasms agent in tetanus, especially in limited resource settings. Further h t 1,2,3 9 20 209 records were identified through database searching,145 full text articles were assessed for eligibility. Inclusion criteria: all RCT’s, PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: Alberta Health Region,Canada; Integrated Pediatric Hospital, Centro Hospitalar S.João, Porto - Portugal, Portugal; ID: 163 / PO2: 13 ID: 280 / PO2: 14 Introduction: he developed fever and trismus. One day prior to the admission he developed flat board abdomen, nuchal rigidity, opistotonus, and seizure. Introduction: Introduction: ID: 209 / PO2: 12 intussusception, impacts the likelihood of successful non-surgical reduction, pain, adverse events and patient/caregiver satisfaction compared Materials and Methods: Sources: medical electronic databases: Google scholar, Ovid, Medline, PubMed, CINAHL, EMBASE, the Cochrane No adverse reactions related with anesthesia or sedation were reported in all reviewed studies. One survey with 78 responders reported less Library, Science Citation Index and Evidence-Based (Non-operative Emergency reduction Medicine – 30.11.2015. Time period : 01.01.1980 Poster Presentation Results: Poster Presentation terminals of lower motor neurons and blocks the release of inhibitory neurotransmitters leading to muscle rigidity, spasms, and seizure. Thetreatment of severe tetanus is still challenging, usually the patient needs to be intubated to control the airway and knocked down to control the seizure. Such facilities may not be available at peripheral health centers. Therefore oral/enteral drugs which reduce spasticity and seizure Purpose: The purpose of this literature review was to determine if analgesia and/or sedation, in children population aged years age with 0 to 17 to children who do not received analgesia and/or sedation. Poster Presentation HYPENTENSION IN ADOLESCENCE – THE FIRST SIGN FOR THE DIAGNOSIS… ADOLESCENCE HYPENTENSION IN Faculty of Medicine University of Indonesia, Ciptomangunkusumo Hospital, Indonesia; [email protected] Portugal; [email protected] Portugal; population of pediatric patients. 60% of eligible studies confirmed that analgesia improves success in both pneumatic andhydrostatics reductions. pediatric intensive team. Thus enteral balofen was added of admission on day 13 at a dose of 9 mg per mg/kg/day, day (0.6 in three devided ENTERAL BACLOFEN FOR TETANUS TREATMENT IN RESOURCE LIMITED SETTINGS IN RESOURCE TREATMENT BACLOFEN FOR TETANUS ENTERAL EFFECTS OF ANALGESIA AND SEDATION ON NON-SURGICAL REDUCTION OF INTUSSUSCEPTION IN CHILDREN: REDUCTION OF INTUSSUSCEPTION ON NON-SURGICAL AND SEDATION ANALGESIA EFFECTS OF Conclusion: Conclusion: Cynthia Centauri would be desirable. Case report: A 4-year-old boy had a history of foul smelling ear discharge since 2 weeks before the admission. Three days before admission using a validated pediatric pain patient score), 3) or parent satisfaction with care provided. no single study with level I of evidence. Despite all above-mentioned limitations, majority of studies found that anesthesia improves outcome in this SYSTEMATIC REVIEW SYSTEMATIC satisfaction after ITS reduction with and without analgesia and/ or sedation. success in ITS reduction with regular use of analgesia. None of reviews studies included assessment of pain or commented about evaluation surveys were completed by radiologists and in 1992. No 1991 surveys were conducted for parents or caregivers or patients. studies were included in final review. Reviewed studies were highly heterogeneous in design, approach, mode of sedation and outcomes. There is studies are suggested before the treatment can be recommended routinely as an alternative anti-spasms agent protocol in all cases of tetanus. [email protected] sedation and/or analgesia (“experimental group”) compared with those who do not (“control group”) Secondary outcomes: differences between 1 1 of pain before and after reduction. There is no single study that used Pain Assessment Scales in children with ITS. The only 2 eligible for review diazepam, so we planned to intubate and gave continuous infusion of midazolam. Unfortunately, there were no availability of ventilator and doses). Subsequently, the seizures frequency and duration were reduced as well as the nuchal rigidity, flat board, and trismus were improved. cohort and case control studies relevant to the subject of the effectsof analgesia and or sedation on non-surgical reduction of intussusceptions. 15 catch-up were given on the outpatient follow-up. of intussusception was introduced Primary in 1980) outcome: the proportion of patients with successful non-surgical reduction who receive (metronidazole and cefotaxime), fluids, and diazepam. Therewas a frequent-persistent seizureeven with a maximum dose of intermittent emergency condition that requires immediate medical intervention. The impact of analgesia and sedation during enema reduction has been experimental and control the group proportion 1) in: of patients with adverse events, pain 2) score or rating (either by patient, parent,or observer assessment for children with ITS using appropriate for age pain scales. are We preparing questioner for parents/caregiver to assess associated with other anomalies. The diagnosis may be late, until a clinic with a high level of suspicion is established - congestive heart failure addressed in the literature but the reported results are inconsistent. Vanessa Oliveira Gorito Veronica Veronica Mugarab Samedi Akanayeva There was no decrease of consciousness. Patient was diagnosed as tetanus and treated with human tetanus immunoglobulin, antibiotics The child discharged from hospital on the day of 19th admission, 2 days after the diazepam and enteral baclofen was stopped. Vaccination

Abstracts The extent of frontal narrowing, extent of lateral narrowing, frontal ratio (FR), and lateral ratio (LR) were analyzed to predict clinical outcomes in in outcomes clinical predict to analyzed (LR) were ratio (FR), lateral ratio and frontal narrowing, lateral of extent narrowing, frontal of extent The Yu-Jun Chang Yu-Jun Also, patients who presented classical triad at diagnosis had better survival than those without (41,5 months vs. 22,45 months). Patients with with Patients months). (41,5 22,45 vs. without months those than survival better had diagnosis at triad classical presented who patients Also, and renal ultrasound). At the consultation, after confirmation of HT, an etiological study was made that revealed no alterations. By notion of of notion By alterations. no revealed that made was study HT,of etiological an confirmation after consultation, At the ultrasound). renal and alerts us for the possibility of an association between mosaics of Turner Syndrome, without other phenotypic manifestations and this pathology. this and manifestations phenotypic other without Turner of Syndrome, mosaics between association an of possibility the for us alerts above 0.6 were discharged to outpatient treatment. outpatient to discharged 0.6 were above emergency department due to headache episode and malaise during exercise, which improved spontaneously. At the examination was was examination At the spontaneously. improved which exercise, during malaise and episode headache to due department emergency causes. secondary of suggestive examination enclosed steeple sign, extent of narrowing, and narrowing ratio on soft tissue neck radiographs were determined before and after treatment. treatment. after and before determined were radiographs neck tissue soft on ratio narrowing and narrowing, of extent sign, steeple enclosed confirmed hemodynamically important CoAO, which motivated referral to Cardiothoracic Surgery. Cardiothoracic to referral motivated CoAO, which important hemodynamically confirmed double (42,86%) in those patients. Regarding frequency of crisis, we observed that patients with more than 10 crisis before diagnosis had the the had diagnosis before 10 crisis than more with patients that observed we crisis, of frequency Regarding patients. (42,86%) those in double the of course the for relevant considered we parameters various on depending rates survival We calculated time. of period years a58 covering objectified HT, witch motivated referral to Pediatrics Consultation. From the anamnesis, she described similar episodes with a year of evolution, of evolution, a year with episodes similar described she anamnesis, the From Consultation. to Pediatrics referral HT,motivated witch objectified clinical factors, fever, age, radiographic findings, and the length of hospital stay were gathered. The initial Westley score (WS), presence of of (WS), presence score Westley initial The gathered. were stay hospital of length the and findings, fever, radiographic age, factors, clinical (PED). department emergency apediatric in treated croup outpatient treatment. Approximately 85% of patients with LR<0.45 remained in the hospital for further care. Almost all patients with LR values values LR with patients all Almost care. further for hospital the in remained LR<0.45 with patients of 85% Approximately treatment. outpatient death in 2.5-3 years. 2.5-3 in death disease, like sex, frequency of crisis, classical triad at diagnosis, hemoglobin level and presence of immunological alterations. We calculated We calculated alterations. immunological of presence and level hemoglobin diagnosis, at triad classical crisis, of frequency sex, like disease, disproportion between upper and lower body segments, it was performed a karyotype that revealed a mosaic of Turner Syndrome (10%). Turner of Syndrome amosaic revealed that akaryotype performed was it segments, body lower and upper between disproportion 1 severe anemia (hemoglobin level under 4,99 g/dl) had the lowest median survival rate of 18,6 months from diagnosis. Also, mortality was was mortality Also, diagnosis. from 18,6 of rate months survival median lowest the had g/dl) 4,99 under level (hemoglobin anemia severe survival rates from onset of the disease and from diagnosis. from and disease the of onset from rates survival We present this case to claim attention to general symptoms and signs presented by adolescents that should be valued underlying underlying valued be should that by adolescents presented signs and symptoms general to attention claim to case this We present more than 10 crises and those who had immunological alterations that improved the survival time. survival the improved that alterations immunological had who those and 10 crises than more with severe is outcome The outcome. a variable has and infiltrates pulmonary and anemia hemoptysis, of atriad as described classically is It She underwent a telemedicine echocardiographic study - which raised the question of coarctation of the aorta (CoAO). A study by Angio-CT (CoAO).Angio-CT by Astudy aorta the of coarctation of question the raised -which study echocardiographic atelemedicine underwent She Conclusion: Conclusion: study analytical ECG, (normal study previous normal motivated already had which spikes, hypertensive and headaches of association with Catalina Bica Catalina We report the case of a 17-year-old female adolescent with menarche at age 13 and regular cycles. She was observed in the the in observed was She cycles. 13 regular age at and menarche with a17-year-old adolescent of female case the We report report: Case Changhua Christian Hospital, Taiwan; [email protected] Hospital, Christian Changhua patients. On the other hand, patients with immunological alterations survived the longest time. We observed a correlation between patients with with patients between acorrelation We observed time. longest the survived alterations immunological with patients hand, other the On patients. patients with croup. with patients Romania, Pediatric Department; Department; Pediatric Romania, Epidemiology Epidemiology Department; [email protected] FR values below 0.23 remained in the hospital for further care, while approximately 98% of patients with FR values >0.65 were discharged to to discharged were >0.65 FRvalues with patients of 98% approximately while care, further for hospital the in remained 0.23 below FR values 2, and typically begins in autumn. As the upper airway narrows, the child may breathe more and more rapid and even feel difficult to breathe, breathe, to difficult feel even and rapid more and more breathe may child the narrows, airway upper the As autumn. in begins typically and 2, Presentation Poster Our purpose is to identify survival rates for patients with IPH. with patients for rates survival identify to is purpose Our Purpose: Results: the etiological study should always be performed, especially in adolescents who have a previous personal/family history or objective objective or history personal/family aprevious have who adolescents in especially performed, be always should study etiological the Presentation Poster We aimed to determine whether various features of neck radiographs can be used to objectively predict outcomes in patients with with patients in outcomes predict objectively to used be can radiographs neck of features various whether determine to We aimed Purpose: department. emergency an in treat to need and worsening rapid for risk at is child the Results: We conducted a retrospective study of patients diagnosed with IPH from eight tertiary pediatric clinics from Romania Romania from clinics pediatric tertiary eight from IPH with diagnosed patients of study aretrospective We conducted Method: and Material Medicine and Pharmacy of Craiova, Romania, Pediatric Department; Department; Pediatric Romania, Craiova, of Pharmacy and Medicine We prospectively recruited 192 patients with croup admitted to the PED between 2012 and 2014. Data regarding 2012 2014. and regarding Data PED between the to admitted croup with 192 patients recruited We prospectively Methods: and Materials INITIAL RADIOGRAPHICFINDINGSINCHILDRENWITHCROUP IN A PEDIATRIC EMERGENCY DEPARTMENT IDIOPATHIC PULMONARY HEMOSIDEROSISINPEDIATRICS PATIENTS: SURVIVAL RATES / PO2: 16 132 /PO2: ID: in early childhood or hypertension (HT) in preadolescents. Although the percentage of cases of primary hypertension increases in adolescence, adolescence, in increases hypertension primary of cases of percentage the Although preadolescents. in (HT) hypertension or childhood early in indicate 5-13% prevalence of Turner Syndrome in girls with CoAo. Despite the association between Turner Syndrome and CoAo, this case case this CoAo, and Turner Syndrome between association the Despite CoAo. with girls in Turner of Syndrome 5-13% prevalence indicate Introduction: / PO2: 15 /PO2: 246 ID: Introduction: the clinical suspicion, because sometimes it traduces important pathology in apparently previous healthy patients. healthy previous apparently in pathology important traduces it sometimes because suspicion, clinical the before diagnosis or if immunological alterations were present. were alterations immunological if or diagnosis before 5-10 to crisis compared higher times two and patients 5crisis than fewer to compared higher times four almost was time Survival survival. best by the end of the fifth year we found only a 15,4% survival. Girls had a median survival rate better than boys boys (35,15 vs. than months). 19,9 months better rate survival median a had Girls a only 15,4%survival. found we year fifth the of end the by University of Medicine and Pharmacy of Craiova, Romania, Pediatric Department; Department; Pediatric Romania, Craiova, of Pharmacy and Medicine of University PO2: POSTER PRESENTATIONS: 2 SESSION We identified 39 cases of IPH in the studied period. In the first year, median survival rate was 74,4% from onset of the disease and and disease the was of rate onset 74,4%from survival year, median first the In period. studied the in IPH of cases 39 We identified The extent of frontal/lateral narrowing and LR were significantly correlated with outpatient status. Approximately 71% of patients with with 71%patients of Approximately status. outpatient with correlated significantly were LR and narrowing frontal/lateral of extent The 20 9 t h Our data suggests a better survival rate of IPH patients if they were girls, with classical triad at diagnosis, with more than 10 crisis 10 crisis than more with diagnosis, at triad classical with girls, were they if patients IPH of rate survival abetter suggests data Our CoAo is a common pathology, and the diagnosis may be late due to non-specific clinical presentation. International studies studies International presentation. clinical non-specific to due late be may diagnosis the and pathology, a common is CoAo

E Idiopathic pulmonary hemosiderosis (IPH) is a rare disorder of unknown etiology which can cause diffuse alveolar hemorrhage. hemorrhage. alveolar diffuse cause can which etiology unknown of disorder arare (IPH) is hemosiderosis pulmonary Idiopathic Croup is the major cause of upper airway obstruction in children. Croup is caused by the human parainfluenza virus types 1 and and 1 types virus parainfluenza human the by caused is Croup children. in obstruction airway upper of cause major the is Croup D 1 , Cristian Gheonea , Cristian I , Chun-Yu Chen T 1 I O 7 N Topics: Topics: Infectious Diseases & Vaccines, Emergency Pediatrics Emergency &Vaccines, Diseases Infectious Rare Diseases 3 University of Medicine and Pharmacy of Craiova, Romania, Pediatric Department; Department; Pediatric Romania, Craiova, of Pharmacy and Medicine of University 2 , Ligia Stanescu , Ligia CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 3 , Liana Cismaru , Liana

5 University of Medicine and Pharmacy of Craiova, Romania, Romania, Craiova, of Pharmacy and Medicine of University 4 , Sorin Dinescu , Sorin 2 University of Medicine and Pharmacy of Craiova, Craiova, of Pharmacy and Medicine of University POSTER SESSION 2 SESSION POSTER 5 4 University of of University 105

Abstracts 106 , Lavinia 1 , Kathrin Nebel 1 1 Department of Preventive Paediatrics, 3 , Max Schwarz 1 Institute for General Practice, University Hospital POSTER SESSION 2 4 , Harald Kaemmerer 1 , Anna Krauß 1,3 , Peter Ewert 1

, Renate Oberhoffer 2 , Nicole Nagdyman 4 , John Venz 2 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE General Pediatrics, Adolescent Health Communication General Pediatrics , Lars Pieper 1 , Linda Sanftenberg 4 Topics: Topics: N 7 O I 1 T I , Sara Rocha, Margarida Marujo, Aldina Lopes D First described in medical literature by Greek radiologist in 1910 Demetrius Chilaiditi, the Chilaiditi sign refers to the rare Due to medical advances, >90% of children with congenital heart disease survive (CHD) into adulthood. The number of adults E

The clinical relevance of Chilaiditi’s sign and syndrome relates to a wide differential diagnosis that includes more serious The need for specific healthcare in patients with CHD is gaining importance, especially since an increasing number of children Patients with mild croup (LR>0.6 and FR>0.65) can receive outpatient care following treatment with single doses of inhaled h t Department of Behavioural Epidemiology, Technical University of Dresden, Germany; 9 20 2 Patients-survey: 954 years, ACHD (36± 12.4 52 % woman) were includedinto analysis. 57% of ACHD had relevant comorbidities. General Practitioners (GP)-survey: 369 GPs were included into analysis. >50% treat CHD patients in the transitional phase from , Jörg Schelling 1 PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: Department of Paediatric Cardiology and Congenital Heart Defects, German Heart Centre Munich, Technical University Munich, known patient-organizations. ACHD reported an inadequate guidance considering health- and life insurance exercise (98%), capacity (80%), ID: / PO2: 177 18 Introduction: Introduction: ID: 268 / PO2: 17 incidental radiologic finding of temporary or permanent hepato-diaphragmatic interposition of the bowel, usually the transverse colon. One in children. In general, patients are asymptomatic and this entity requires no treatment in the absence of symptoms. When associated with located inside a colon segment, withno free intraperitoneal Blood air. tests showed a rise in inflammatory and markers 9,14mg/dl) (CRP lack of transition. IT’S A PNEUMOPERITONEUM? OH NO, IT’S CHILAIDITI’S SIGN! OH NO, PNEUMOPERITONEUM? A IT’S Materials and Methods: In a cross-sectional, questionnaire- based survey, medical health supply of ACHD was evaluated regarding type-, Seidel Rhoia Clara Rhoia Neidenbach Poster Presentation Pedro Mantas the blood culture was negative. The patient was admitted for observation and started on antibiotics for pneumonia. She remained stablethroughout her admission, with no associated gastrointestinal symptoms or worsening radiological changes and she was discharged home Purpose: The aim of this study is the analysis of the “actual care situation” of ACHD in Germany, regarding both patients and primary care Results: treated by general practitioners Certified (>70%). specialists and centers are known in only 39% of the cases, less than 40%ACHD of had Results: transition to ACHD specialized institutions and doctors. A better awareness for ACHD and GPs about the nationwide certified supply is relevant,to cover patients medical needs and to reduce morbidity and mortality. treatment and admitted if necessary. Patients with severe croup (LR<0.45 and FR<0.23) should be hospitalized after initial treatment. Poster Presentation Department of Sport and Health Sciences, Technical University of Munich, Germany; Pediatric Department. Hospital de Santarém. Santarém, Portugal; [email protected] LACK OF SPECIALIZED HEALTH CARE IN CONGENITAL HEART DISEASE DUE TO INSUFFICIENT TRANSITION? DISEASE DUE TO HEART CARE IN CONGENITAL LACK OF SPECIALIZED HEALTH patient and initial management of Chilaiditi’s syndrome is conservative, patients should be kept under clinical and radiologic observation in published report estimated the worldwideincidence at 0.025-0.028% and although it is more common in older adults, it has been reported physician’s point of view. pregnancy and genetics (47%). Case report: A seven-year-old female, with no relevant medical history and normal development, presented acutely with a six day history of Conclusion: Cardiac sequelae and residual diseases such and as arrhythmia pulmonary heart (29%), vascular failure (11%) diseases are mainly (5%) Conclusion: Conclusion: with congenital heart disease in Germany (ACHD) has approached >280.000, suffering from serious sequelae, residua and complications with number-, age-, gender-distribution, comorbidities of CHD as well as needs, knowledge and local distribution of specific medical care. Germany; symptoms, typically gastrointestinal or respiratory, it is designated as Chilaiditi’s syndrome. significant effects on morbidity and mortality. The majorityACHD(>200.000) of is not tied to a specialized doctor/centre, which is related to a survive into adulthood. ACHD supply in Germany is not sufficient. Medical care is mainly carried out by primary care providers due to a failing 1 order to prevent complications. coughing and pyrexia, with the exception of being apyrexial Physical on day four. examination was normal except for tympany on percussion over the right upper quadrant of the abdomen. A plain chest radiograph showed a right lower lobe consolidation with a small pleural effusion conditions such as pneumoperitoneum, which requires urgent surgical management. Although no intervention is required for an asymptomatic of the Ludwig-Maximilians-University Munich, Germany; [email protected] childhood into the adult age. 82% of GPs treat ACHD with simple moderate and Specialists (65%), (32%) complex CHD (24%). and Centers comorbidities such as heart arrhythmia failure and (43%), pulmonary (45%) hypertension (18%). epinephrine and dexamethasone. Patients with moderate croup 0.45-0.6 (LR: and 0.23-0.65) FR: should be closely monitored after initial and hepato-diaphragmatic interposition of the colon known as Chilaiditi’s sign. The observed colonic haustration suggested the gas was after three days. are consulted in only 23%. GPs are not aware of certified institutions in more than 50% of the cases, although they treatACHD with complex

Abstracts Jang Hoon Lee Hoon Jang Ajou University School of Medicine, Korea, Republic of (South Korea); (South [email protected] of Republic Korea, Medicine, of School University Ajou algorithm and its further evaluation. further its and algorithm (0.26; 0.07-0.92; p=0.037) and absence of purulent material on ultrasound (0.07; 0.02-0.29; p<0.001). Size of lymph node (0.98; 0.96-1.00; (0.98; 0.96-1.00; node lymph of p<0.001). Size (0.07; 0.02-0.29; ultrasound on material purulent of absence and 0.07-0.92;(0.26; p=0.037) consultation to prior use (0.91;(OR; 95%CI):(1.17; antibiotic count age no p=0.001), 0.87-0.96; cell blood white absolute 1.06-1.29; p=0.002), (yes/no). ultrasonography at material purulent (x10^9/L), and (SGAI) (36.8% (7/19) vs. 7.9% (5/63), P = 0.006) and bronchopulmonary dysplasia (BPD) (100% (19/19) dysplasia P=0.001) 56.4% (39/63) more vs. were (7/19)(SGAI) (36.8% 7.9% bronchopulmonary vs. and (5/63), P=0.006) conservative management should include those predictive factors. predictive those include should management conservative decade. last the over published been have guidelines others, age (years), size of lymph node (mm), fever (38,5°C) and antibiotic use prior to consultation, fluctuation, absolute white blood cell count count cell blood white absolute fluctuation, consultation, to prior use (mm), antibiotic node and (38,5°C) fever lymph of (years), size age others, among including, covariates, independent potential several with models regression logistic univariate performed we outcome, afavorable of disease, Cat-scratch disease, Kawasaki adenitis, were: mycobacterial criteria Exclusion LBACL. was diagnosis final the which of mass cervical defined as outpatient treatment or hospital stay of 48 hours or less without surgical drainage. To identify factors at initial consultation predictive predictive consultation initial at factors identify drainage. To surgical without less or hours 48 of stay hospital or treatment outpatient as defined 1 OUTCOME seem to better evolve than other children with likely bacterial acute cervical lymphadenitis. A decision algorithm to identify patients eligible for for eligible patients identify to algorithm Adecision lymphadenitis. cervical acute bacterial likely with children other than evolve better to seem Université Laval; Laval; Université SGAI were associated with severe hypophosphatemia in this population and severe hypophosphatemia may become a predictive factor of BPD. of factor apredictive become may hypophosphatemia severe and population this in hypophosphatemia severe with associated were SGAI years old who have consulted for LBACL between July 1st 2010 and July 31st 2015 at a tertiary care pediatric center. LBACL were identified identified were LBACL center. pediatric care 31st 1st 2010 July July 2015 and atertiary at between LBACL for consulted have who old years Conclusion: using 2 electronic record databases (hospitalization, emergency). Patients were included if they had acute (≤10 days) episode of unilateral unilateral of (≤10 acute days) had episode they if included were Patients emergency). (hospitalization, databases record 2electronic using Conclusion: was started later than Control group (N=63) (73 [61; 88.5] vs. 85 [71.5; 142.0], hours after birth, P = 0.036). Small for gestational age infants infants age gestational for Small P=0.036). birth, [61; [71.5; (73 85 vs. after 142.0], 88.5] hours (N=63) group Control than later started was acids amino of introduction early with ELBWI in hypophosphatemia severe with p=0,057) or fluctuation (0.71; 0.21-2.39; p=0.57) did not achieved statistical significance. statistical achieved not did (0.71; p=0.57) fluctuation or 0.21-2.39; p=0,057) were outcome favorable with (diagram1). associated 27(16,9%) Factors outpatient as which treated from were evolution a favorable presented [email protected], [email protected] QC, Canada; Canada; QC, prevalent in Hypophosphatemia group. Hypophosphatemia in prevalent LIKELY BACTERIAL ACUTE CERVICAL LYMPHADENITIS INCHILDREN:FACTORS PREDICTIVEOFFAVORABLE LATE SUPPLEMENTATION OFPHOSPHORUSIS ASSOCIATED WITHSEVEREHYPOPHOSPHATEMIA INELBW few studies whether lower phosphorus supply develops severe hypophosphatemia in extremely low birth weight infants (ELBWI) with early early with (ELBWI) infants weight birth low extremely in hypophosphatemia severe develops supply phosphorus lower whether studies few Philippon Presentation Poster Results: adecision create to order in children in LBACL of management the in outcome favorable with associated factors clinical To identify Purpose: Karina Deshaies Poliquin KarinaDeshaies Presentation Poster Results: factors clinical associated the analyze and birth after week first the during hypophosphatemia severe of incidence the To investigate Purpose: Laval, Québec, QC, Canada; Canada; QC, Québec, Laval, This retrospective observational study was based on the review of medical records of patient from 1 month to 18 to 1month from patient of records medical of review the on based was study observational retrospective This Methods: and Materials INFANTS WITHEARLY INTRODUCTIONOF AMINO ACIDS Eighty-two ELBWI were enrolled in this study. Medical records were reviewed retrospectively. Severe Severe retrospectively. reviewed were records Medical study. this in enrolled were ELBWI Eighty-two Methods: and Materials in 139(83,7%) patients and cervical tomodensitometry in 31(18,7%). Surgical drainage was performed in 35(21,1%). in 31(18,7%). in performed was 68(41,0%) drainage Overall, patients Surgical tomodensitometry cervical and 139(83,7%)in patients / PO2: 19 /PO2: 153 ID: Introduction: introduction of amino acids. amino of introduction Introduction: / PO2: 20 179 /PO2: ID: hypophosphatemia was defined as a level of serum phosphate < 2mg/dL during the first week after birth. after week first the during 2mg/dL < phosphate serum of level as a defined was hypophosphatemia bilateral cervical lymph node involvement, congenital malformation, immunodeficiency or underlying neoplasia. Favorable evolution was was evolution Favorable neoplasia. underlying or immunodeficiency malformation, congenital involvement, node lymph cervical bilateral official no as surgery to antibiotherapy from widely vary may and advice expert on relies (LBACL) mainly lymphadenitis cervical acute bacterial Department of Pediatrics, Centre-Mère-Enfant-Soleil, CHU de Québec - Université Laval, QC, Canada; Canada; QC, Laval, -Université Québec de CHU Centre-Mère-Enfant-Soleil, Pediatrics, of Department PO2: POSTER PRESENTATIONS: 2 SESSION Our final study cohort was composed of 166 patients with a mean age of 4,5 years (3,5SD) and 62% male. Ultrasound was obtained obtained was Ultrasound male. 62% and (3,5SD) years of 4,5 age mean a with of patients 166 composed was cohort study final Our 23.2% (19/82) of ELBWI had severe hypophosphatemia. In Hypophosphatemia group (N=19), the supplementation of phosphorus phosphorus of (N=19), group supplementation the Hypophosphatemia In (19/82) hypophosphatemia. severe had 23.2% ELBWI of 5 20 9 , Josée-Anne Gagnon , Josée-Anne t h Severe hypophosphatemia was common in ELBWI with early introduction of amino acids. Late supplementation of phosphorus and and phosphorus of supplementation Late acids. amino of introduction early with ELBWI in common was hypophosphatemia Severe Older patients without prior antibiotic use, those with lower absolute white blood cell count and no purulent material on ultrasound ultrasound on material purulent no and count cell blood white absolute lower with those use, antibiotic prior without patients Older

E Cervical lymphadenitis is frequent in the pediatric population and usually the result of infectious agents. Management of likely likely of Management agents. infectious of result the usually and population pediatric the in frequent is lymphadenitis Cervical In recent studies, it has been reported that early aggressive amino acids supply causes hypophosphatemia. there have been been have there hypophosphatemia. causes supply acids amino aggressive early that reported been has it studies, recent In 5 D Department of Surgery, Centre-Mère-Enfant-Soleil, CHU de Québec - Université Laval, QC, Canada; karina.deshaies- Canada; QC, Laval, -Université Québec de CHU Centre-Mère-Enfant-Soleil, Surgery, of Department I T 1 , Moon Sung Park Sung , Moon I O 7 3 Population Health and Optimal Health Practices Research Unit, Centre de recherche du CHU de Québec Université Université Québec de CHU du recherche de Centre Unit, Research Practices Health Optimal and Health Population N Topics: Topics: 1 , 4 Laurence Arsenault-Blanchard Laurence Department of Emergency Medecine, Centre-Mère-Enfant-Soleil, CHU de Québec - Université Laval, Laval, -Université Québec de CHU Centre-Mère-Enfant-Soleil, Medecine, Emergency of Department Neonatal Nutrition General Pediatrics, Infectious Diseases &Vaccines Diseases Infectious Pediatrics, General 1 CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 1 , Alexandre Marceau Alexandre ,

POSTER SESSION 2 SESSION POSTER 2 , Richard Bélanger Richard, 2 Faculty of Medecine, Medecine, of Faculty 3 , Simon Berthelot Simon , 4 , Daniel Daniel , 107

Abstracts 1 108 2 , IreneCarvalho 1 , Ana Maia 1 Department of Pediatrics. 2 , Célia Madalena 2 Department of Ophthalmology, 2 , Carolina Faria 2 POSTER SESSION 2 , Carlos Sistelo 2 , Paulo Ferreira 2

, Augusto Magalhaes 1 Taichung Veterans General Hospital, [email protected] Taiwan; 2 , Hernâni Brito 1 , Vicente Rey y Formoso 1 2 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE , Marta I Pinheiro 1 Infectious Diseases & Vaccines, Orthopaedics General Pediatrics, Epidemiology General Pediatrics Topics: Topics: Topics: N 7 O I , Fang-Liang Huang Fang-Liang , 1 1 T I D Neonatal brachial plexus palsy is (NBPP) a motor and sensory disturbance of the upper limb, related to injuries of the spinal Peri-orbital cellulitis is an infection of the eyelid and soft tissues surrounding the without eye affecting the ocular globe. It is an Although non-typhoidal Salmonella is the main cause of human salmonellosis, non-typhoid Salmonella infection complicated E

The NBPP is a complication in some unpredictable ways before birth, leaving many children with physical and motor disabilities of In our experience, we suggested that magnetic resonance imaging (MRI) is useful equipment for spondylodiscitis examination, h t 9 20 Retrospective and descriptive study through the consultation of the clinical records and/or clinical trial of the newborns with brachial There were 60 newborns 53% were female. with The NBPP, incidence was 1,06%. Instrumental vaginal childbirth happened in 50% In total patients 183 were included: with 126 pre-septal and with 57 post-septal cellulitis. The mean ages for pre- and post-septal PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: Changhua Show Chwan Memorial Hospital, Taiwan; Department of Pediatrics, Integrated Pediatric Hospital, Centro Hospitalar S.João, Porto - Portugal; Department of Pediatrics. Integrated Pediatrics Hospital, Centro Hospitalar de S. João, Porto-Portugal; ID: 165 / PO2: 22 Introduction: 0.3 percent of live births. The only established risk factor for NBPP isshoulder dystocia. There are other risk factors, none however, of these ID: 270 / PO2:21 Introduction: ID: 255 / PO2: 23 low back pain. diagnosed We a spondylodiscitis of vertebral bodies L5–S1 (between lumbar 5 and sacral due to Salmonella 1) species group Methods: Materials and Methods: A retrospective analysis of medical reports of patients years old) (<18 admitted to Hospital de São João in Porto– Background: Poster Presentation Purpose: The aim of this study was to know the NBPPincidence, the characteristics of them and their evolution. Results: Poster Presentation Purpose: characterize To a population with peri-orbital cellulitis and compare the clinical features of pre and post-septal cellulitis. Results: the most frequent predisposing cause of disease in both cases (70,6%vs.84,2%). The most common clinical features were fever (44,8%) Poster Presentation favorable evolution: 4 belonged 3 to to Erb Erb Palsy Palsy, Plus and 1 newborn with complete paralysis. Fifty percent of these newborns factors have demonstrated a statistically significant predictivevalue for the occurrence of NBPP frequent in post-septal cellulitis (p=0,033). Laboratory tests showed leukocytosis and increased in 47,5% CRP in 79,8%. No complications NON-TYPHOID SALMONELLA INFECTION OF A CHILD COMPLICATED WITH SPONDYLODISCITIS IN TAIWAN CHILD COMPLICATED A INFECTION OF NON-TYPHOID SALMONELLA NEONATAL BRACHIAL PLEXUS PALSY – A REVIEW A – PLEXUS PALSY BRACHIAL NEONATAL Portugal over a 10-year period with peri-orbital cellulitis. Diagnosis was confirmedTC-scan. by Comparison of both pre- and post-septal PEDIATRIC PERI-ORBITAL CELLULITIS: A 10 YEAR REVIEW OF PATIENTS ADMITTED INTO A TERTIARY HOSPITAL IN HOSPITAL TERTIARY A ADMITTED INTO YEAR REVIEW OF PATIENTS 10 A CELLULITIS: PERI-ORBITAL PEDIATRIC PORTUGAL premature. The median birth weight was 3705g, 30% were macrosomic. had a diabetic 15% mother. The right arm was impaired in 65% of the plexus lesion at the Pediatric Service of the Hospital Póvoa doVarzim / Vila do Conde between 2010-2016 Conclusion: Centro Hospitalar da Póvoa de Varzim/Vila do Conde, Póvoa de Varzim-Portugal; [email protected] Centro Hospitalar S.João, Porto - Portugal; [email protected] C1 infection,C1 and totally recovered with cefotaxime therapy. Cristina Ferreras LLamazares Ferreras Cristina uncommon condition occurring mostly in children. It is divided into pre-septal and post-septal cellulitis depending upon the infection being were described among patients with pre-septal cellulitis, whereas in post-septal patients cellulitis had complications: (7,6%) 14 7 subperiosteal with ceftriaxone in most however, post-septal (65%) cellulitis multiple (59,6% p<0,01) antibiotics were preferred. Surgical sinus drainage was Conclusion: with spondylodiscitis is still a rare condition in immunologically normal children and it is difficult to diagnose. Case Report: In this study, we describe the case of an immunologically normal girl with 11-year-old initial pneumonia and subsequently felt left many degrees.Early identification and orientation is essential to minimize the appearance of sequelae. newborns. It was detected to paralysis by asymmetrical Moro reflex in 53% of the cases, an asymmetry of the upper limb in of 25% the cases newborns were discharged with complete resolution of the paralysis. Using the Narakas Classification, the(8 13%other newborns) without nerves that constitute the brachial plexus and it is usually a birth complication. NBPP is uncommon, with an incidence that ranges from 0.04 to required surgical intervention. 1 1 1 different entities with distinct clinical implications. Despite being less common, post-septal cellulitis is more serious and can lead to severe of cases and a newborn with NBPP was born by cesarean. Shoulder dystocia occurred in 55% of birth. In this study newborns) 6% (4 were complications. Hence the importance of early diagnosis and treatment. cellulitis concerning epidemiology, clinical presentation, treatment, complications and outcome. cellulitis were 3,9±3,6 and 6,5±6,8 years respectively. Post-septal cellulitis was more common in older patients (p=0,018). Sinusitis was other clinical finding showed statistically significant differences between pre- and post-septal cellulitis. The majority of cases were treated and crepitation of the clavicle of the newborns. in 21% All were sent for consultation of Physical and RehabilitationMedicine, being 87% of the anterior to the orbital septum including the surrounding soft tissues or posteriorly, involving the orbit. Although clinically similar, they are two and ophthalmologic findings such as peri-orbital swelling(96,2%) and/or erythemaPhotophobia and ocular(69,4%) (18%). painwas more abscesses, 5 orbital abscesses with (2 cerebral empyema), 1 central venous thrombosis and periosteal 1 abscess. No laboratory test or and followed by microbiological diagnosis is also essential for decision of appropriate choice of antibiotic treatment. Tiago Augusto Paiva de Magalhaes Tsung-Hua Wu

Abstracts .Residents and faculties have different attitudes and skills related to self-assessment and SDL, Better understanding their knowledge and and knowledge their understanding Better SDL, and self-assessment to related skills and attitudes different have faculties and .Residents January 2015 – June 2017, in our primary paediatric practice. Descriptive statistical analysis was used. was analysis statistical Descriptive practice. 2015 2017, paediatric –June January primary our in Ahmed Alhammadi Ahmed Hassan, Manasik Abdelrahman, Hatim Maarafiya, Muna Siddiq, Khaled Elghawaby, Ahmed additionally at their first systematic examination at 1 month of age. The mean age of the patients who received Prevenar 13 was 14 months, age age Prevenar 13 was months, 14 received who patients the of age mean The age. of month at 1 examination systematic first their at additionally experience will guide residency program on how best to teach and further develop these skills. Postgraduate residents desire more guidance guidance more desire residents Postgraduate skills. these develop further and teach to best how on program residency guide will experience children received 2 doses of vaccine. Most of the children had an older sibling with complicated Rotavirus infection before, so parents decided decided parents so before, infection Rotavirus complicated with sibling older an had children the of Most vaccine. of 2doses received children considered one of the main new methods in medical education and teaching. Despite the importance of self-assessment to lifelong learning, learning, lifelong to self-assessment of importance the Despite teaching. and education medical in methods new main the of one considered days. None of the vaccinated children later developed Rotavirus infection. Rotavirus developed later children vaccinated the of None days. on how to engage in SDL, Residency programs need to provide explicit education during early years of the residency training on process of of process on training residency the of years early during education explicit provide to need programs Residency SDL, in engage to how on (45%vs 30%) goals write resident their helping comfortable less but P=0.03), %, 50 vs (80% skills own concept. Questions offered objective answers utilizing 5-point Likert scale that can be used to perform statistical analysis. statistical perform to used be can that scale Likert 5-point utilizing answers objective offered Questions concept. the insure to used be can that methods and skills To identify program. training pediatric the into SDL implement to faculty and residents of dose, only 5 (5,76%) patients received 4 doses. None of the patients vaccinated during the first year of life with at least 2 doses developed IPD. developed doses 2 least at with life of year first the during vaccinated patients the of None 4doses. received 5(5,76%) only patients dose, studies had shown that physicians have limited ability to self-assess, therefore skills need to be developed to insure implanting and success of of success and implanting insure to developed be to need skills therefore self-assess, to ability limited have physicians that shown had studies rate of vaccination against Rotavirus infection. The mean age of the children who received Rotarix was 4 months, age range 2 to 6 months All All 6months 2to range age 4months, was Rotarix received who children the of age mean The infection. Rotavirus against vaccination of rate low avery is which Rotarix, 13 (1,44%) Only received 10 in fever cases. and children reactions, site injection mostly cases, 30 in registered success implantation of SDL in training program training in SDL of implantation success In all cases of IPD children weren’t vaccinated prior the disease, but parents decided to vaccinate them after the recovery. Side effects were were effects Side recovery. the after them vaccinate to decided parents but disease, the prior vaccinated weren’t children IPD of cases all In 1 received (22,98%) 12 20 (13,79%) (57,47%) 50 vaccine, of 3doses, 2doses patients received the of received Most months. 30 2to from range Good understanding of SDL and how to construct effective Individualized Learning Plan (60%) and (50%) respectively. Faculty can assess their their assess can Faculty (50%) respectively. (60%) and Plan Learning Individualized effective construct to how and SDL of understanding Good SDL among resident and faculty. and resident among SDL no other laboratory or clinical finding able to differentiate between pre- or post-septal cellulitis. Hospitalization was longer in post-septal cases. cases. post-septal in longer was Hospitalization cellulitis. post-septal or pre- between differentiate to able finding clinical or laboratory other no SDL, while Faculty modeling of SDL motivate learners and provide opportunity to demonstrate the process the demonstrate to opportunity provide and learners motivate SDL of modeling Faculty while SDL, Conclusion: Conclusion: Croatia. There are opportunities for prevention in the form of vaccines, which are not yet included in the national routine vaccination program in Croatia. in program vaccination routine national the in included yet not are which vaccines, of form the in prevention for opportunities are There Croatia. Conclusion: vaccine Rotarix in our primary paediatric practice. paediatric primary our in Rotarix vaccine performed in 15 cases of post-septal cellulitis. Hospitalization was longer in post-septal cellulitis (10,21±8,6days p=0,002). Every patient had a a had patient Every (10,21±8,6days p=0,002). cellulitis post-septal in longer was Hospitalization cellulitis. post-septal of 15 in cases performed PNEUMOCOCCAL AND ROTAVIRUS VACCINATION INPRIMARY PAEDIATRIC CAREINCROATIA PERCEPTION AND ATTITUDES TOWARD SELF-DIRECTEDLEARNING AMONG PEDIATRIC RESIDENTS AND Prevenar 13 and Rotarix. It would be beneficial if these were included in the national routine vaccination program in Croatia. in program vaccination routine national the in included were these if beneficial be would It 13 Rotarix. Prevenar and FACULTIES IN ACGMEI PEDIATRIC RESIDENCY PROGRAM-QATAR Prevenar 13 and 13 children (1,44%) received Rotarix. All parents were advised to vaccinate their child with Prevenar 13 and Rotarix 13 Rotarix Prevenar and with child their vaccinate to advised were parents All (1,44%) Rotarix. 13 13Prevenar and children received favorable outcome. favorable to vaccinate this child. We registered side effects in 2 children, one had traces of blood in the stool for 2 days and the other had diarrhea for 3 3 for diarrhea had other the and 2days for stool the in blood of traces had one 2children, in effects side We registered child. this vaccinate to to support transition from undergraduate to postgraduate learning. Self -directed learning is supporting the concept of lifelong learning and is is and learning lifelong of concept the supporting is learning -directed Self learning. postgraduate to undergraduate from transition support to Results: 13 Rotavirus Prevenar and vaccine Conjugate 13-valent Pneumococcal with vaccinated patients of number the evaluate to was Aim Purpose: Results: readiness To the faculty. explore and residents pediatric among Learning Self-directed self-assessment, of concept To the explore Purpose: Presentation Poster Health facility Zagreb Center, Croatia; [email protected] Center, Croatia; Zagreb facility Health Presentation Poster Hospital, main tertiary hospital in Qatar. It includes; details of demographics, perception, attitude and experience toward Self-directed learning learning Self-directed toward experience and attitude perception, demographics, of details includes; Qatar. It in hospital tertiary main Hospital, Background: [email protected] Qatar; corporation,Doha, medical Hamad Helena Živić Helena We retrospectively collected and analysed electronic data of children aged 2 months-3 years in the period from from period the in years 2months-3 aged children of data electronic analysed and collected We retrospectively Methods: and Materials Methods: Both forms had favorable outcomes in most cases. most in outcomes favorable had forms Both Introduction: / PO2: 24 /PO2: 168 ID: / PO2: 25 /PO2: 266 ID: PO2: POSTER PRESENTATIONS: 2 SESSION From a total of 900 patients aged 2 months-3 years, in the period from January 2015 – June 2017, 87 children (9.66%) received 2015 2017, –June (9.66%) January received from children 87 period the in years, 2months-3 aged patients 900 of atotal From Out of 99 respondents, 50%residents and 49%faculties. 90 percentage of both perceived lifelong learning as necessary to physicians. physicians. to necessary as learning lifelong perceived both of percentage 90 49%faculties. and 50%residents respondents, 99 of Out A cross sectional survey administered among pediatric residents and faculties from July -November 2016 in Hamad General General 2016 Hamad in -November July from faculties and residents pediatric among administered survey sectional Across 20 9 t h Most cases of IPD and Rotavirus infection occur in otherwise healthy children and could be prevented by existing vaccines vaccines existing by prevented be could and children healthy otherwise in occur infection Rotavirus and IPD of cases Most Post-septal cellulitis is more common in older patients. Although photophobia is more frequent in post-septal cellulitis, there are are there cellulitis, post-septal in frequent more is photophobia Although patients. older in common more is cellulitis Post-septal Faculty believe that SDL improve patient care. They comfortably identify area of strength and improvement compared to residents residents to compared improvement and strength of area identify comfortably They care. patient improve SDL that believe Faculty

E Self-assessment, self-directed learning (SDL) is one of the cornerstones for new era of teaching. Considered as one of the ways ways the of one as Considered teaching. of era new for cornerstones the of (SDL) one is learning self-directed Self-assessment, Invasive pneumococcal disease (IPD) and Rotavirus infections are a significant health problem among infants and toddlers in in toddlers and infants among problem health asignificant are infections (IPD) Rotavirus and disease pneumococcal Invasive D I T 1 I O 7 N Topics: Topics: General Pediatrics General Infectious Diseases &Vaccines Diseases Infectious CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER

POSTER SESSION 2 SESSION POSTER 109

Abstracts 110 POSTER SESSION 2

POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE Obesity & Physical Activity General Pediatrics, Infectious Diseases & Vaccines Infectious Diseases & Vaccines, Orthopaedics , Mayela Solis Baltodano, Roger Garcia Puig, Evelyn Berbel Topics: Topics: Topics: N 7 O I 1 T I Cross-sectional and observational study. The study population consisted of a sample schoolchildren of 1892 aged between 3 , Naohiro Kamiyoshi, Masaaki Kugo D Overweight and childhood obesity are public a health priority, especially in developed countries, because their high prevalence Salmonella spondylitis is a rare disease, and it is known as an uncommon complication of Salmonella infection in E

This is the very first case report of pyogenic spondylitis caused by Salmonella saintpaul. Salmonella should be considered as a The prevalence of overweight in Martorell schoolchildren According was 31.4%. to the multivariate analysis, in our municipality, We estimate We that the prevalence in Martorell reaches similar rates to those of countries with high prevalence and that the high h t 9 20 The prevalence of excess (22% overweight weight was 31.4% obese). Overweight and 9.4% in girls higher was 5.9% than (p = 0.01) in PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: boys. They of students were overweight: over 9 years of children 35.1% of age, 37.2% enrolled in public schools and almost 50% of children of Introduction: ID: 272 / PO2:26 ID: 134 / PO2: 28 however when to perform these invasive interventions remains controversial. Introduction: ID: 136 / PO2: 27 immunocompetent children. prevent treatment To failure and neurological deficits, it needs prompt diagnosis and sufficient effort to identify IMMUNOCOMPETENT 13-YEAR-OLD CHILD: A CASE REPORT A IMMUNOCOMPETENT 13-YEAR-OLD CHILD: Methodology: Materials and Methods: looked We at all children who attended the emergency department with a booking in diagnosis of unwell/feverish Shota Myojin Hypothesis: Latin American mothers, as well as obesity, the 12.8% children of Maghrebi. Leeds Teaching Hospital, United Kingdom; [email protected] Latin American mother, adding the Maghreb origin of the mother for obesity. The trend over the period remained stable. Hospital Sant Joan de Deu Martorell, Spain; [email protected] Himeji Red Cross Hosipital, Japan; [email protected] Results: Rebecca Jane Fiona Powell Purpose: As part ofthe development of new sepsis guidelines in response to the national CQUIN and new NICE guidelines on sepsis in to see how the new guidelines would affect management. Poster Presentation Poster Presentation the causative organism, and definitive therapy should be started as soon as possible. The positive rates of blood cultures are generally low. the risk factors associated with overweight and obesity female were: sex, age over 9 years old, attending public school and being the son of a Poster Presentation failure, and a high index of suspicion is needed for prompt diagnosis especially when blood cultures are negative. Invasive interventions such find the source of infection. Paediatrics we undertook a retrospective audit comparing the new guidelines to previous cases that had attended our emergency department RECOGNITION OF SEPSIS IN THE PAEDIATRIC EMERGENCY DEPARTMENT EMERGENCY RECOGNITION OF SEPSIS IN THE PAEDIATRIC PYOGENIC SPONDYLITIS AND PARAVERTEBRAL ABSCESS CAUSED BY SALMONELLA SAINTPAUL IN AN IN SAINTPAUL SALMONELLA ABSCESS CAUSED BY AND PARAVERTEBRAL PYOGENIC SPONDYLITIS PREVALENCE OF OVERWEIGHT AND OBESITY IN THE PAEDIATRICA POPULATION OF MARTORELL POPULATION IN THE PAEDIATRICA OBESITY AND OF OVERWEIGHT PREVALENCE poultry eggs, or contact with poultry and its feces. Definitive antibiotic therapywas started. After a 6-week hospitalization, washe discharged percentage of immigrant population of our área could befactor a of influence in their . Conclusion: Conclusion: Case Report: report We a case of a 13-year-old boy with 4-month history of occasional high fever and 3-month history of lower back pain, who was diagnosed with spondylitis of the L4-5 vertebral bodies and paravertebral abscess. Initial blood cultures were negative, therefore a single set of observations. re-hospitalized 2 weeks after discharge, and surgical debridement was performed which led to the detection of Salmonella saintpaul as the Objective: The objective of this to assess study 1) was: the prevalence of excess weight in children attending schools in our municipality to 2) determine the association with different variables that could influence their appearance.3) analyze the trend throughout the study period. obesity according to IOTF standards. The prevalence of excess weight was analyzed according to the sex, age, type of school and nationalityof the mothers. child. reviewed We sets 153 of notes and compared the initial observations to the new NICE guidelines for the septic child. causative pathogen of pyogenic spondylitis in immunocompetent children. Identifying the causative organism is essential to prevent treatment clinical improvement. During this course, we did not perform invasive interventions since the clinical course was favorable. he was However, causative pathogen. Through thorough medical history taking, it was revealed that the possible source of infection was consumption of raw shown that a single set of observations does not predict severity of illness but rather the trend of the observationssignificance. show more With the significant sign of illness being loss of beat to beat variability of heart rate which cannot be established after empirical antibiotic treatment was started intravenously. He responded well to initial conservative management, and was discharged after and health consequences. Due to this increase Spain has come to occupy one of the first positions excessin weight rates. years,and 12 who attended the 7 schools in the municipality. BMI was calculated by measuring weight and height, and defined overweight and as CT-guided biopsy should be considered even if the clinical course seems to be uncomplicated. a detailed Taking social history can help to and is currently under follow-up observation at our outpatient clinic with good recovery. Ana Moreira Echeverria As part of the audit we looked at the literature available around observations and predicting significant illness based on these have There are some other options to identify the causative organism such as Computed Tomography (CT) guided biopsy or surgical debridement,

Abstracts The main purpose of the analyses is to ascertain which policies are effective and therefore have the potential to protect children and and children protect to potential the have therefore and effective are policies which ascertain to is analyses the of purpose main The and decision making in the safe environment. safe the in making decision and as learning traditional than benefit and engage more making, decision and thinking critical facilitate session the feedback; positive some up add as raised respiratory rate or heart rate. Of the 64 cases 55 of them would not have been appropriate to treat as sepsis. Of the 9 cases that that 9cases the Of sepsis. as treat to appropriate been have not would them of 55 cases 64 the Of rate. heart or rate respiratory raised as alone. Therefore, it may be beneficial to use SBME teaching of pediatric resuscitation in undergraduate medical students. medical undergraduate in resuscitation pediatric of teaching SBME use to beneficial be may it Therefore, alone. adolescence and reduce smoking rates among them. among rates smoking reduce and adolescence experiment with legal and illegal substances and make their first experiences with tobacco, alcohol, and other drugs. These experiences often often experiences These drugs. other and alcohol, tobacco, with experiences first their make and substances illegal and legal with experiment of the session very useful 121/132 (92%) and have more confidence to apply the knowledge in the future future have the They in 115/132 (87%)students. knowledge the apply to 121/132 useful confidence very more have (92%) and session the of cost saved by discharging (correctly) the 55 children was £22000. Because of this audit we have created a sepsis flow chart to help with with help to chart flow asepsis created wehave audit this of Because £22000. was children 55 the (correctly) discharging by saved cost the night one for hospital to admission and antibiotics IV received children these all had so £400 is hospital in stay night asingle of cost diagnoses but were not septic. Of the 153 children reviewed in the ED over 125 of them were discharged home with no adverse events. adverse no with home discharged were 125 ED over the them of in reviewed 153 children the Of septic. not were but diagnoses students. There was 117/132 (89%) felt that the scenarios was realism and appropriate for the level of learner. The summarized and debriefing debriefing and summarized The learner. of level the for appropriate and 117/132 was realism was There students. scenarios the that (89%) felt questionnaires. evaluation program and self-evaluation by evaluated was course The debriefing. of 10 by minutes followed and simulation case run will minutes 20 Next Support. Life Advanced Pediatrics and Support Life Basic Pediatric teaching: skill of minutes 30 has session senior paediatric staff. This chart is currently in use and we are auditing its use within the emergency department. emergency the within use its auditing weare and use in currently is chart This staff. paediatric senior To evaluate the use of SBME teaching of pediatric resuscitation in medical students. medical in resuscitation pediatric of teaching SBME of To use the evaluate Objective: received IV antibiotics, only one had a concluding diagnosis of sepsis and required intensive care admission. The other 8 cases had infective infective had 8cases other The admission. care intensive required and sepsis of diagnosis aconcluding had one only antibiotics, IV received smoking prevalence among adolescents. among of prevalence smoking reduction asignificant to lead policies control tobacco of range awide of implementation acomprehensive that conclusion the supports Institute for Health Promotion and Disease Prevention, Austria; [email protected] Austria; Prevention, Disease and Promotion Health for Institute management of medically unwell children and have used elements from the sepsis 6 and NICE guidelines as well as considering opinions of of opinions considering as well as guidelines NICE 6and sepsis the from elements used have and children unwell medically of management SIMULATION-BASED PEDIATRIC RESUSCITATION INUNDERGRADUATE MEDICAL EDUCATION measure by conducting logistic regression analysis. regression logistic conducting by measure policy/ each of influence the calculated 2013 We Europe”. then in Scale Control “Tobacco the from obtained policies control tobacco national national spending on public information campaigns as well as compulsory large direct health warning labels on cigarette packs are associated associated are packs cigarette on labels warning health direct large compulsory as well as campaigns information public on spending national Conclusion: Conclusion: Conclusion: Gunter Maier Gunter policy measures in the field of tobacco control/prevention and the actual smoking behavior of 15-year old students in 33 European countries. countries. 33 European in students old of 15-year behavior smoking actual the and control/prevention tobacco of field the in measures policy EFFECTIVE? REDUCTION AND PREVENTIONOFTOBACCO USE AMONG ADOLESCENTS -WHICHPOLICY MEASURES ARE population level. Our analyses clearly confirm this assumption: in countries where cigarette prices are relatively low, 15 year old students are are low,students old 15 year relatively are prices cigarette where countries in assumption: this confirm clearly analyses Our level. population the lecture. the Results: [email protected] Thailand; University, Mahidol Hospital, Ramathibodi Medicine of Faculty Pediatrics, of Department Due to the high risk nature of pediatric resuscitation, it is unlikely that clinical competence in this area can be developed by bedside teaching teaching bedside by developed be can area this in competence clinical that unlikely is it resuscitation, pediatric of nature risk high the to Due fewer adolescents who smoke. who adolescents fewer Presentation Poster Results: the smoking behavior of 15-year old students, which serve as basis for our analyses. We supplemented the HBSC-Data with information on on information with HBSC-Data the We supplemented analyses. our for basis as serve which students, old 15-year of behavior smoking the Using recent data from the Health Behavior in School-aged Children (HBSC) study we examine the relationship between health health between relationship the examine we study (HBSC) Children School-aged in Behavior Health the from data recent Using Purpose: of focus the in equally are therefore adolescents and adulthoodChildren in behavior addictive and health- future of foundation the lay times Presentation Poster high places, public and work- smokefree on legislation strict Additionally high. are prices where countries to compared smoke to likely as twice Results: Uthen Pandee Methods: The HBSC study conducted in 2014 in 42 countries and regions across Europe and North America provides data on on data provides America North and Europe across regions and 2014 in countries 42 in conducted study HBSC The Methods: and Materials investigations. This would have had a significant financial and resource implication of unnecessarily treating children as septic. The average The average septic. as children treating unnecessarily of implication resource and financial asignificant had have would This investigations. / PO2: 29 /PO2: 287 ID: Introduction: health promotion efforts or health policy initiatives as well as marketing departments of tobacco and alcohol corporations. alcohol and tobacco of departments marketing as well as initiatives policy health or efforts promotion health Introduction: / PO2: 30 173 /PO2: ID: PO2: POSTER PRESENTATIONS: 2 SESSION A total of 132 medical students attend the simulation sessions. Almost of them were very valuable learning experience 123/132 (93%) experience learning valuable very were them of Almost sessions. simulation the attend students 132 of medical Atotal Of the 153 notes reviewed 64 (41.8%) fell into the high-risk criteria for sepsis. Most this was due to one raised parameter such such parameter raised one to due was this Most sepsis. for criteria (41.8%) 64 reviewed high-risk 153 the notes the into Of fell Increasing the price of cigarettes is widely regarded as most effective measure in order to reduce smoking prevalence on a a on prevalence smoking reduce to order in measure effective most as regarded widely is cigarettes of price the Increasing Group of sixth year medical student from pediatric rotation attend simulation session from March 2015 to February 2016. The 2016. The 2015 February to March from session simulation attend rotation pediatric from student medical year sixth of Group 20 9 t h The medical students value pediatric resuscitation medical simulation highly as the learning strategy to enhancing critical thinking thinking critical enhancing to strategy learning the as highly simulation medical resuscitation pediatric value students medical The further and admission required and antibiotics IV received have would children 64 followed been guidelines NICE new the Had Some of the measures we examined seem to have an impact on the smoking behavior of adolescents. The data at hand also also hand at data The adolescents. of behavior smoking the on impact an have to seem examined we measures the of Some

E Simulation-based medical education (SBME) has been increasing use to be the effective teaching tool in medical education. education. medical in tool teaching effective the be to use increasing been has (SBME) education medical Simulation-based Adolescence is the stage of life where certain behavioral patterns develop and solidify. During this time adolescents typically typically adolescents time this During solidify. and develop patterns behavioral certain where life of stage the is Adolescence D I T 1 I O 7 N Topics: Topics: Adolescent Health Choices General Pediatrics, Emergency Pediatrics Emergency Pediatrics, General CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER

POSTER SESSION 2 SESSION POSTER 111

Abstracts 112 POSTER SESSION 2

, Ana Maria Ferreira, Joana Rodrigues, Denise Schmitt, Margarida Azevedo , Sashikumar Ganapathy POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE Rare Diseases, Preterm Infant Emergency Pediatrics Emergency Adolescent Health Communication Adolescent Health Topics: Topics: Topics: , Abu Syed Golam Faruque N 7 O I 1 T I D Subcutaneous fat necrosis is a rare clinical entity, which affects mostly term and post-term newborns. Although it’s a self limited Heat disorders are common in Singapore due to its tropical climate. Studies of paediatric heat injuries are and few; there have Gastrointestinal symptoms lead to morbidity in pregnancy, yet remain an unexpectedly under-researched topic. Infectious E

Our study results highlight the yrs ≤18 of age, rural women and remarkable infectiousness of Salmonella in pregnant women with Heat disorders are common worldwide and especially so in Singapore given the tropical climate. Our study has shed some light h t 9 20 A total of 229 (12%) pregnant A total of 229 women (12%) were visited to the Dhaka and Matlab icddr,b hospital for diarrheal illness. The analyzable 58 patients presented to our paediatric emergency department for heat injuries between 2005 of which and 2015, 45 cases were PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: been no Singaporean studies on this topic. Our study hopes to fill this gap in knowledge. ID: 298 / PO2: 33 Introduction: ID: 184 / PO2:31 Introduction: Introduction: ID: / PO2: 191 32 identified for analysis. The greatest number presented with heatexhaustion males(18 18 females), followedand by heatstroke in males (6), icddr,b, Bangladesh, People’s Republic [email protected] of; 6.93)] after6.93)] controlling for other co-variates. Materials and Methods: conducted We a retrospective study of patients between years 0 and of age 17 presenting to our paediatric Materials and Methods: During - Oct, a total 2013 July, 2016, of 1836 female aged 15-49 years patients attended in the Dhaka and Matlab Shahnawaz Ahmed KK Women’s and Children’s Hospital, Singapore; [email protected] Poster Presentation Results: Hospital of icddr,b, Bangladesh. Among them we have recruited 229 pregnant women who reported diarrhea with pregnancy as case and the risk of late complications, namely hypercalcemia. Poster Presentation Purpose: hope We to study the epidemiology and patterns of heat injury in Singapore. With this data, we aim to make recommendations in Results: those were not pregnant but reported with diarrhea considered as control They were included (1607). into the hospital based Diarrheal Disease Purpose: The present analysis aimed to underscore clinical, socio-demographic and etiological characteristics of pregnant women with Poster Presentation females (2), andfemales heat cramps (2), in Most males of our (2). patients were between years and old. 14 12 The majority of heat disorder cases were 2005 and 2015. DIARRHEA, ETIOLOGY, PREGNANT WOMENIARRHEA AMONG PREGNANT WOMEN VISITED TO ICDDR, B HOSPITAL AMONG PREGNANT WOMEN VISITED TO PREGNANT WOMENIARRHEA DIARRHEA, ETIOLOGY, p<0.052), no treatment of drinking water (86% vs. p<0.006) 78%; and monthly income (92% of the vs. 86%; family p<0.019) (>100$), pregnancy with diarrhea compare to opposed group. In multivariate analysis, significant associations with diarrhea among pregnant women pathology, with spontaneous resolution without sequelae, adequate management and follow-up of these patients is extremely important due to vs. dehydration 72%, p <0.001), number status <0.001), p <0.007) of stool vs. (66% (55% 81%, hrs), vs. (>10times/24 observed 74%, lower in pre-hospital and emergency department management which we hope will reduce the incidence, as well as the morbidity of heat disorders Conclusion: Case Report: A male preterm newborn was delivered at 33 gestational weeks after a preterm premature membrane rupture with placental CHEDV, Portugal; [email protected] Portugal; CHEDV, was detected more commonly amongst pregnant mother with diarrhea relative to their counterparts. Use of antibiotic prior to hospital (38% were observed with Salmonella and age CI-2.04-6.76)], (95% group 3.71 3.83 rural [OR: [OR: CI- (95% CI-1.07-2.25)] (95% site 2.12- 1.55 [OR: Conclusion: SUBCUTANEOUS FAT NECROSIS IN A PRETERM NEWBORN – AN ATYPICAL CASE ATYPICAL AN PRETERM NEWBORN – A NECROSIS IN FAT SUBCUTANEOUS SOCIO-DEMOGRAPHIC, CLINICAL CHARACTERISTIC AND ETIOLOGY OF DSOCIO-DEMOGRAPHIC, CLINICAL, OF AND ETIOLOGY CHARACTERISTIC SOCIO-DEMOGRAPHIC, CLINICAL SINGAPORE PAEDIATRIC HEAT INJURY STUDY - A TEN-YEAR REVIEW A - STUDY INJURY HEAT SINGAPORE PAEDIATRIC Surveillance System where (DDSS) 2% systematic surveillance patients from urban Dhaka Hospital and Health and Demographic Surveillance System patients (HDSS) from rural Matlab Hospital. sample was 229 pregnant women with diarrhea in which from 86 (38%) Dhaka hospital from and (62%) Matlab 143 hospital who admitted significantly higher among the pregnant women with diarrhea compared to counterpart. 10%Only reported diarrhea during 1sttheir trimester Wen Neo, Yang Samuel En Ci Quek survived till discharge with no sequelae. patients 18 However, developed end organ involvement, with 3 patients requiring intensive care, and 2 diarrhea and emphasize the need of active surveillance and comprehensive approach for prevention and control strategies. during this period. Mean age ±SD was 25±3.4, use vs. p<0.001), of 3%; non-sanitary whilst maternal yrs age ≤18 (11% toilet (40% vs. 33%; diarrhea reported to the icddr,b hospital in Bangladesh. diarrhea is common inpregnancy but still poorly understood in developed as well as developing countries like Bangladesh. developing long term neurological sequelae. clinical management and prevention of heat injuries in children. on the local prevalence, contributing factors, management and outcomes of heat disorders. have highlighted We areas of improvement in both emergency department who were diagnosed with heat disorder. studied We the demographic and clinical data over a ten-year period between exertional with an environmental component - usually involving sports in hot There weather. were no deaths during this period. Most patients and pregnant rest 90% women (29% vs. 61%) developed diarrhea during 2nd and 3rd trimester respectively. vs. 6%, Salmonella p <0.001) (14% abruption. A cesarean section was performed due to acute fetal distress. Birth weight was 2425g. There was no need for resuscitation, only Alexandra Martins, Benedita Bianchi de Aguiar

Abstracts THE ASSOCIATION BETWEENPHYSICAL ACTIVITY AND GENERAL LIFESATISFACTION INLOWERSECONDARY a posterior rib fracture dated between two to three weeks old, further raising the suspicion for non-accidental injury. The survey also revealed revealed also survey The injury. non-accidental for suspicion the raising further old, weeks three to two between dated fracture rib a posterior always negative from the D13 on. The newborn was reassessed with 1 month and 13 days of life, maintaining a slight induration on the leg, but but leg, the on induration aslight 13 maintaining life, of and days 1month with reassessed was D13 newborn the The on. from negative always antibiotics and elevated were procalcitonin and protein day. same reactive C the during progressed signs inflammatory the of aggravation (Table). A final model explained 36.9% of the SLSS variability. Self-esteem is the main predictor of SLSS and a mediator of the association association the of mediator a and SLSS of predictor main the is Self-esteem variability. SLSS the of 36.9% explained (Table).model Afinal environment as variables. independent general paediatric team in a unique position as we were confronted with a conflict of professional opinion between two specialities. Further Further specialities. two between opinion professional of aconflict with confronted were we as position aunique in team paediatric general caused by venous puncture as a portal of entry, Either way, subcutaneous fat necrosis is a rare entity which needs clinical awareness due to to due awareness clinical needs which entity arare is necrosis fat way, Either subcutaneous entry, of aportal as puncture venous by caused concerns about low bone density. Bloods taken at the time revealed normal full blood count, urea and electrolytes, liver function tests and bone bone and tests function liver electrolytes, and urea count, blood full normal revealed time the at taken Bloods density. bone low about concerns demographic factors, Vigorous Physical Activity (VPA), self-esteem, family affluence, family relations and the perception of the school school the of perception the and relations family affluence, family (VPA), self-esteem, Activity Physical Vigorous factors, demographic of the leg continued to progress, but there was no analytic aggravation. Flucloxacillin was replaced but vancomycin. An ultrasound excluded excluded ultrasound An vancomycin. but replaced was Flucloxacillin aggravation. analytic no was there but progress, to continued leg the of 1 social inclusion. social safeguarding assessment. We should also acknowledge additional stress when a medical diagnosis is made with long-term health sequelae. health long-term with made is diagnosis amedical when stress additional acknowledge also We should assessment. safeguarding supplementary O2, which was maintened for 48h and chest x-ray was compatible with a transient tachypnea of the newborn. Hypocalcemia Hypocalcemia newborn. the of tachypnea atransient with compatible was x-ray chest and 48h for maintened was which O2, supplementary remained normal afterwards – this may be related to the low gestational age of the newborn, since published cases are mainly of term term of mainly are cases published since newborn, the of age gestational low the to related be may –this afterwards normal remained newborn The necrosis. fat subcutaneous of diagnosis the suggesting ultrasound, by confirmed were which areas, calcification subcutaneous University, Faculty of Pedagogy, Department of Biomedical Foundations of Development and Sexology; [email protected]. Sexology; and Development of Foundations Biomedical of Department Pedagogy, of Faculty University, measured with the Students’ Life Satisfaction Scale (SLSS) – shortened version. Hierarchical linear models were estimated by introducing introducing by estimated were models linear Hierarchical version. (SLSS) –shortened Scale Satisfaction Life Students’ the with measured newborns. The etiology is still questionable, but may be due to sepsis, anoxia induced by local trauma during venous puncture or infection also also infection or puncture venous during trauma local by induced anoxia sepsis, to due be may but questionable, still is etiology The newborns. young people who do not engage in VPA and those who exercise every day, the mean SLSS index increases from 4.23 to 4.90 (p<0.001) (p<0.001) 4.90 to 4.23 from increases index SLSS day, mean the every exercise who VPA in those and engage not do who people young SUSPECTED NON-ACCIDENTAL INJURY: THEDOUBLE-EDGEDSWORD Conclusion: SCHOOL STUDENTS:THEROLEOFINDIVIDUAL AND FAMILY FACTORS Conclusion: four. type imperfecta osteogenesis of adiagnosis revealed later, results months Three occurred. had fractures no whom with was diagnosed on D3 (min 6,3mg/dL), with need for oral supplementation until D16 and presenting with normal leves afterwards. On D12 On of afterwards. leves normal with D16 presenting until and supplementation oral for need with (min 6,3mg/dL), D3 on diagnosed was Conclusion: level. calcium including normal, were results Laboratory manipulations. ate pain no and signs inflammatory no with were markers inflammatory Analytic manipulation. at pain no and signs inflammatory the of improvement with life, of D34 on discharged was signs Inflammatory cloacae. an Enterobacter showed day same this of Hemocuture gentamicin). and cefotaxime (flucloxacillin, initiated were In view of history and concern of non-accidental injury, the patient was admitted and underwent a skeletal survey which revealed revealed which survey askeletal underwent and admitted was patient the injury, non-accidental of concern and history of view In Report: Case members. family different three least at of care the in whilst potential serious complications. profile. The case and results were discussed with the local and tertiary paediatric radiology team who advised in absence of no concerning concerning no of absence in advised who team radiology paediatric tertiary and local the with discussed were results and case The profile. pl Engaging adolescents from the poorest families in physical activity may contribute to an improvement of their self-efficacy and enhance their their enhance and self-efficacy their of improvement an to contribute may activity physical in families poorest the from adolescents Engaging Paediatricians should always put the safety of patients first and we often aware of the stress placed on the family when a child undergoes a undergoes child a when family the on placed stress the of aware often we and first patients of safety the put always should Paediatricians features of low bone density and query underlying metabolic bone disease influencing the occurrence of the multiple fractures. This left the the left This fractures. multiple the of occurrence the influencing disease bone metabolic underlying query and density bone low of features contrary, the On injury. non-accidental for suspicious highly was this posterior, being fractures rib the of view in and density bone of features fracture of left fibula. He had a history of multiple previous fractures. It was established that the fractures had occurred at different times and and times different at occurred had fractures the that established It was fractures. previous multiple of history a had He fibula. left of fracture Results: Presentation Poster were there that convinced were and fractures multiple of history the about concerns their stated team disorders bone metabolic regional the taking into account individual assets and family factors. family and assets individual account into taking adolescents, in satisfaction life general and activity physical between association the investigate to was paper the of objective The Purpose: affluence. family of impact the considered have studies afew Only activity. physical of effects health the on research in account into taken Presentation Poster Background: NAI, balanced with the knowledge that an alternative medical diagnosis with long term health problems would otherwise be implicated. implicated. be otherwise would problems health term long with diagnosis medical alternative an that knowledge the with balanced NAI, Dorota Wiktoria Kleszczewska Wiktoria Dorota [email protected] Kingdom; United Deanery, West North Edwards Lauren The survey conducted in the 2015 involved 4,085 lower secondary school Polish students. Life satisfaction was was satisfaction Life students. Polish school secondary lower 4,085 2015 the in involved conducted survey The Methods: and Material life, inflammatory signs appeared on anterior surface of the right leg and right ankle, with pain during manipulation. Fever, hipotension and and Fever,hipotension manipulation. during pain with ankle, right and leg right the of surface anterior on appeared signs inflammatory life, investigations were undertaken and whilst results were awaited the child was placed in the care of paternal grandmother, the only close relative relative close only the grandmother, paternal of care the in placed was child the awaited were results whilst and undertaken were investigations intra-articular compromise. On D16 a painful induration was noticeable on the location of the previous inflammatory signs. An x-ray showed showed An x-ray signs. inflammatory previous the of location the on noticeable was induration D16 On apainful compromise. intra-articular / PO2: 35 241 /PO2: ID: / PO2: 34 /PO2: 192 ID: Introduction: between VPA and SLSS. As family affluence decreases, the impact of physical activity on self-esteem becomes stronger. becomes self-esteem on activity physical of impact the decreases, affluence family VPA As SLSS. and between Institute of Mother and Child, Warsaw, Poland; Poland; Warsaw, Child, and Mother of Institute PO2: POSTER PRESENTATIONS: 2 SESSION On average, life satisfaction among adolescents was M=4.66 (SD=2.23) which is 52% of the maximum score. In a comparison of of acomparison In score. maximum the of 52% is which (SD=2.23) M=4.66 was adolescents among satisfaction life average, On 20 9 t h Family material status may modify the impact of physical activity on the variability of the SLSS scores in school-aged children. children. school-aged in scores SLSS the of variability the on activity physical of impact the modify may status material Family We have reflected upon the effect of the double-edged sword in such cases: the hope that the results would not indicate indicate not would results the that hope the cases: such in sword double-edged the of effect the upon We reflected have This case demonstrates an atypical case of subcutaneous fat necrosis, since calcium levels were low at the beginning and and beginning the at low were levels calcium since necrosis, fat subcutaneous of case atypical an demonstrates case This

E The relationship between physical activity and psychosocial health is widely discussed. The effect of demographic factors is is factors demographic of effect The discussed. widely is health psychosocial and activity physical between relationship The A three-year-old male presented to a hospital in the North West of England with a left femoral spiral fracture and a bowing abowing and fracture spiral femoral aleft with England of West North the in ahospital to presented male Athree-year-old D I T 1 I O 7 , Anindya Mukherkee , Anindya N Topics: Topics: Child Mental Health, Adolescent Wellbeing Adolescent Health, Mental Child General Pediatrics, Injuries &Trauma Injuries Pediatrics, General 1 , Anna Dzielska , Anna CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 2 Institute of Mother and Child, Department of Child and Adolescent, Poland; Poland; Adolescent, and Child of Department Child, and Mother of Institute 2 , Agnieszka Małkowska-Szkutnik , Agnieszka

POSTER SESSION 2 SESSION POSTER 3 , Joanna Mazur , Joanna 2 3 Warsaw Warsaw 113

Abstracts 114 4 University of Dundee, 2 , Antony Morgan 1 University of Hertfordshire, School of 3 POSTER SESSION 2 , Gerald Humphris 3

, Irene García-Moya 1 Assotiacion “World in Pictures”, Bosnia and Herzegovina; [email protected] 2 2 Glasgow Caledonian University London, UK; [email protected] 4 , Candace Currie 1 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE Child Mental Health Mental Child Adolescent Wellbeing General Pediatrics, Child Mental Health Topics: Topics: Topics: , Mirna Mlaco Hrkic 1 N 7 O I , Francisco Ribeiro-Mourão, Ana de Carvalho Vaz, Vera Gonçalves, Mariana Costa, Hugo Rodrigues 1 T I Aixa Y. Alemán-Díaz, Aixa Y. D 2 This is a comparative case presentation between two boys who had the same symptoms, passed same diagnostic procedures This systematic review summarises the scientificevidence base on the benefits of involving young people in thedevelopment, Choking Phobia defines a specific intense fear of choking on food,beverages, or pills, withoutany organic abnormalities being E

The first boy has no progress in psychomotor development but the second boy hasvery a good progress and he is going in There is in literature a lack of descriptions of Choking Phobia, perhaps due to a wide variety of terms used for this condition, h t Occupational speech and physical therapy for two years in assotiacion “world in Pictures” with child psychologist, logoped and 9 20 PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: Health Center Zenica, Bosnia and Herzegovina; University of St Andrews, WHO Collaborative Centre for International Child and Adolescent Health UK; Policy, barriers and facilitators associated with the meaningful, appropriate and effective involvement of young people. ID: 110 / PO2: 37 ID: 110 Introduction: / PO2:ID: 214 38 Introduction: Introduction: identifiable trigger may be absent. It appears to be more frequent in early adolescence, and some authors estimate the period between onset ID: 271 / PO2:36 implementation and evaluation of programmes aiming to secure health and its related outcomes. MRI -no abnormalities for second first boy, one didn’t do it, ABR test - normal hearing for second first boy, one didn’t do it, ocular examination- Methods and Results: Both boys have young and healthy parents. Family history - negative on neurological diseases. Psychomotor Sanda Kadiric-KasapSanda Health and Social UK; Work, CRIPACC, Poster Presentation time, with prolonged chewing on small bites, careful inspection of each food element, and avoidance of solid elements. Given this information,the hypothesis of Choking Phobia was considered, and efforts were concentrated on behavioral therapy, which were successful - the patient Poster Presentation Purpose: The objectives describe (1) werethe to: range of theoretical perspectives to develop appropriate logic models that can help to Poster Presentation PedroMarinho Pediatrics Department, Unidade de Saúde Local do Alto Minho, Hospital de Santa Luzia, Portugal; [email protected] DISABILITIES preschool education The now. difference, during these two years, was in parental involvement in work with their sons. the Even first was boy probably underestimating its prevalence. It is also commonly misdiagnosed as an eating disorder or a conversion disorder. In this case, the present. It is usually traced back to a past traumatic event involving choking, that happened or to, was witnessed the patient; by, this however, Case report: The authors report the case of a previously healthy 6-year-old female, admitted to the Pediatric Emergency Department with Conclusion: Conclusion: necessary to prevent the deleterious long-term consequences, since it appears to have a good prognosis, given early detection. School of Nursing and Health Sciences, Dundee Centre for Health and Related Research, UK; no disturbance. – no disturbance. EEG make explicit pathways to health and wellbeing; assess (2) the evidence of the impact that involving young people can have on programme social educator. 1 1 days post-discharge, the patient had increased Kg in weight, 1,4 and the parents described normal diet patterns. described that for the previous 3 weeks the patient’s diet had been comprised of mostly yogurt, refusing to eat solid food elements, with during school lunch. The physical examination of the patient did not unveil any abnormalities. Using the available records, it was established development seemed normal until the months, age of 12 able to sit, smile, pronounces few words. the At physical examination in the age don’t want a surgical treatment so this boy had an recurring urinary infections. In the age of 32 month he was diagnosed an disharmonious development, undeveloped speech. The second boy was not coming to a doctor until the age of 4,5 years and then he was diagnosed an disharmonious development, undeveloped speech. Neuropediatric examination: no clear neurological deficit. Laboratory analysis - normal, of 18 monthsof 18 they had no progress in development of speech and was noticed a reduce of attention, the parents were meet and explained gradually accepting increasing amounts of solid foods, and decreasing anxious behavior at mealtime. In a follow-up outpatient evaluation, 20 earlier started with the treatment he has weaker success. effectiveness; synthesize (3) the accumulated knowledge on the views that young people have of being involved; understand and, (4) the and detection ranges from 2 to 45 years. acute-onset periumbilical pain, and a maternal perception of an excess of saliva, which the patient avoided swallowing. The parents also accompanying intermittent bouts of abdominal pain. This was later associated with a choking episode with a piece of steak, that occurred a drop in WHO weight percentile curves, from 50-85th to 15-50th percentile. Blood tests did not present any pathological findings andabdominal an ultrasound was reported as normal. During the inpatient it was stay, possible to assess the behavior of the patient during meal about possibilities of diagnostic and therapeutic treatments. The first boy had to visit a doctor more often because he has an bronchialasthma, fluticasone propionate inhaler in therapy but the parents couldn’t accept this diagnose and therapy. He also has a phimosis but they and had same treatment during two years. age of the patient represented an increased challenge regarding biopsychosocial assessment. In literature, both pharmacologicaland SSRI’s) (p.e. cognitive-behavioral therapy, or their combination, have been used as treatment strategies. Increased awareness of Choking Phobia is Anna Gavine Treatment: THE INVOLVEMENT OF YOUNG PEOPLE IN PROGRAMMES TO SECURE HEALTH - SYSTEMATIC REVIEW FINDINGS - SYSTEMATIC HEALTH SECURE IN PROGRAMMES TO YOUNG PEOPLE OF THE INVOLVEMENT THE IMPACT OF PARENTAL INVOLVEMENT ON THE PSYCHOMOTOR DEVELOPMENT OF CHILDREN WITH DEVELOPMENT THE PSYCHOMOTOR ON INVOLVEMENT OF PARENTAL THE IMPACT THE FEAR OF EATING - A CASE REPORT A - THE FEAR OF EATING

Abstracts TINU SYNDROME-TWOCASESREPORTS THIRD LEVEL HOSPITAL and ibuprofen was the most commonly implied drug. One case was associated with a rotavirus infection. Acute kidney injury manifested manifested injury kidney Acute infection. arotavirus with associated was case One drug. implied commonly most the was ibuprofen and (n=5/10) identified factor apredisposing with cases among cause common most the was NIA 15 of (12-16.5yr).age years NSAID-associated effects in health behaviours, especially tobacco use and healthy eating where consistent significant positive effects were identified. However, we identified. were effects positive significant consistent where eating healthy and use tobacco especially behaviours, health in effects positive some demonstrated also have programmes These behaviours. of range awide across knowledge for effects consistent found we example examination was normal. Laboratory tests revealed elevation of serum creatinine, BUN and cistatin C, glycosuria, proteinuria, microalbuminuria and and microalbuminuria proteinuria, C, glycosuria, cistatin and BUN creatinine, serum of elevation revealed tests Laboratory normal. was examination WHAT ISCAUSING ACUTE INTERSTITIAL NEPHRITISINTHEPEDIATRIC AGE GROUP?–THEEXPERIENCEOF A eosinophiluria. Eight (62%) patients were treated with corticosteroids and only 1 case needed peritoneal dialysis. The median (P25-P75) time time (P25-P75) median The dialysis. peritoneal needed 1case only and corticosteroids with treated were (62%) patients Eight eosinophiluria. of young people’s involvement to programme effectiveness, an aspect that warrants further attention in the future. the in attention further warrants that aspect an effectiveness, programme to involvement people’s young of cases of TINU, with different presentation and clinical course, but still both illustrative of this disorder. this of illustrative both still but course, clinical and presentation different with TINU, of cases two We report time. same the at present always not are they although uveitis, and (TIN) nephritis tubulointerstitial acute both by characterized diseases were excluded. Ultrasonographic (US) examination of the abdomen and pelvis showed increased kidney echogenecity and scintigraphy scintigraphy and echogenecity kidney increased showed pelvis and abdomen the of (US) examination Ultrasonographic excluded. were diseases development of the intervention, delivery of the intervention and evaluation of the intervention. The majority of studies were conducted in high- in conducted were studies of majority The intervention. the of evaluation and intervention the of delivery intervention, the of development diagnosed with AIN. with diagnosed considered. be also should (TINU) uveitis with nephritis tubulointerstitial and infections as such factors, causal (NSAIDs), other but drugs 1 striking picture signalling a lack of high-quality research to inform policies and programmes aiming to do just that. This is a critical weakness in in weakness acritical is This that. just do to aiming programmes and policies inform to research high-quality of alack signalling picture striking related to the development of health behaviours. Such programmes have demonstrated the capacity to engage and empower young people, for for people, young empower and engage to capacity the demonstrated have programmes Such behaviours. health of development the to related revealed bilateral cortical lesions. He presented anterior uveitis two months later and topic corticosteroids were started. Kidney histology showed TIN. TIN. showed histology Kidney started. were corticosteroids topic and later months two uveitis anterior presented He lesions. cortical bilateral revealed University of Porto; Porto; of University regression of the abnormal urinary findings previously described and a normal abdominal and pelvic US examination. pelvic and abdominal normal a and described previously findings urinary abnormal the of regression related and non-drug related types. The most common cause of AIN, in all age groups, is related to the use of non-steroidal anti-inflammatory anti-inflammatory non-steroidal of use the to related is groups, age all in AIN, of cause common most The types. related non-drug and related Twelve-year-old-boy admitted to our department because of elevation of serum creatinine level. Two weeks before, he presented presented he Two level. before, weeks creatinine serum of elevation of because department our to admitted Twelve-year-old-boy Report: Case uveitis are associated. Despite frequent recurrences of uveitis, complete resolution of renal changes is common. Systemic corticosteroids may may corticosteroids Systemic common. is changes renal of resolution complete uveitis, of recurrences frequent Despite associated. are uveitis Conclusion: was normal. Three months later, he repeated laboratory tests, revealing normal renal function, normal serological and immunological study and and study immunological and serological normal function, renal normal revealing tests, laboratory later, repeated he months Three normal. was examination physical his and asymptomatic was He β2-microglobulinuria. and glycosuria of because department our to admitted associated, was Conclusion: with the maximum serum creatinine values (ρ =0.22; p=0.019) but no association was found with the use of corticosteroids. of use the with found was association no but p=0.019) (ρ =0.22; values creatinine serum maximum the with correlated was recovery full until days of number The recovery. function renal full experienced 8(5-10) was patients all and days recovery until presented 9(69%). in None erythrocyturia 12 and in (92%) cases present was leukocyturia admission, On 3cases. in only oliguria with Centro Hospitalar de São João, Portugal; [email protected] Portugal; João, São de Hospitalar Centro vomiting, nausea and anorexia and he reported common asthenia and one episode of foamy urine. He consumed tea plants frequently. Physical Physical frequently. plants tea consumed He urine. foamy of episode one and asthenia common reported he and anorexia and nausea vomiting, people are involved in multiple components of participation and also compare the effects between young people actually involved in the the in involved actually people young between effects the compare also and participation of components multiple in involved are people β2-microglobulinuria. Acute EBV, CMV, parvovirus B19, herpes simplex 1 and 2, mycoplasma and clamydea pneumonia infections and auto-immune auto-immune and infections pneumonia clamydea and mycoplasma 2, 1and EBV, B19, simplex Acute CMV, herpes parvovirus β2-microglobulinuria. found limited effect on behaviour for most other outcomes. Evaluation in the existing studies failed to separately examine the specific contribution contribution specific the examine separately to failed studies existing the in Evaluation outcomes. other most for behaviour on effect limited found the evidence that affects research, policy and programme design and its effectiveness in this area. More high quality studies in which young young which in studies quality high More area. this in effectiveness its and design programme and policy research, affects that evidence the Presentation Poster programmes. effective of replication and evaluation implementation, the Results: Presentation Poster Results: SPSS. in performed was analysis Statistical reviewed. were records Clinical AIN. of diagnosis the with hospital, tertiary patients pediatric in outcome, poor for factors risks the as well as characteristics, clinical and epidemiological the To describe Purpose: Sofia Helena Ferreira Helena Sofia Because he presented impairment of renal function associated to histological abnormalities, we decided to use oral corticosteroids. Eleven-year-old- corticosteroids. oral use to decided we abnormalities, histological to associated function renal of impairment presented he Because Biomédicas Abel Salazar, University of Porto; [email protected] Porto; of University Salazar, Abel Biomédicas Retrospective analysis of all children and adolescents aged <18 years, admitted as inpatients from 2001 to 2016 to a 2001 in from inpatients as admitted <18 years, aged adolescents and children all of analysis Retrospective Methods: and Materials interventions. We support the development of reporting standards to improve transparency and research practices, as well as tools that enable enable that tools as well as practices, research and transparency improve to standards reporting of development the We support quality high interventions. replicate to others allows that reporting scientific better encourage we Additionally, necessary. are delivery and/or implementation sexual with topics health of arange on (i.e. 10-19 focused and olds) year adolescents at targeted exclusively were Programmes countries. income Inês Maio Inês 39 /PO2: 257 ID: programmes of arange in used being are people young with approaches participatory that indicates Analysis common. most the being health / PO2: 40 /PO2: 207 ID: Introduction: Introduction: boy, with history of anterior uveitis with initial good improvement after treatment with topic corticosterois, but, because of recurrence, methotrexate methotrexate recurrence, of because but, corticosterois, topic with treatment after improvement good initial with uveitis anterior of history boy, with be considered in progressive or significant renal disease. renal significant or progressive in considered be Pediatrics Department, Centro Materno Infantil do Norte, Centro Hospitalar do Porto and Instituto de Ciência Biomédicas Abel Salazar, Salazar, Abel Biomédicas Ciência de Instituto and Porto do Hospitalar Centro Norte, do Infantil Materno Centro Department, Pediatrics PO2: POSTER PRESENTATIONS: 2 SESSION The search identified 42 unique studies that involved young people in one or more of: issue identification, needs assessment, assessment, needs identification, issue of: more or one in people young involved that studies unique 42 identified search The Thirteen patients were included in the present analysis, 7 boys and 6 girl, with a median (25th percentile-75th percentile, P25-P75) P25-P75) percentile, percentile-75th (25th amedian with 6girl, and 7boys analysis, present the in included were patients Thirteen 1 20 9 , Liane Correia-Costa , Liane t h Involving young people in programmes enables them to actively participate in matters that affect them. This review draws a a draws review This them. affect that matters in participate actively to them enables programmes in people young Involving In conclusion, the cases described regard a rare disease, highlighting the necessity to consider this diagnosis when TIN and and TIN when diagnosis this consider to necessity the highlighting disease, arare regard described cases the conclusion, In

E Acute Interstitial nephritis (AIN) is an increasingly important cause of acute kidney injury and is classically divided into drug- into divided classically is and injury kidney acute of cause important increasingly an is (AIN) nephritis Interstitial Acute Tubulointerstitial nephritis and uveitis syndrome (TINU) is a rare disease and it affects more commonly young adult females. It is is It females. adult young commonly more affects it and disease arare is (TINU) syndrome uveitis and nephritis Tubulointerstitial D I T 1 I O 7 N 2 Pediatric Nephrology Unit, Centro Materno Infantil do Norte, Centro Hospitalar do Porto and Instituto de Ciências Ciências de Instituto and Porto do Hospitalar Centro Norte, do Infantil Materno Centro Unit, Nephrology Pediatric , Ana Teixeira, Helena Pinto Helena Teixeira, , Ana Topics: Topics: General Pediatrics General General Pediatrics, Epidemiology Pediatrics, General 1,2 , Teresa Costa , Teresa CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER 1,2 , Conceição Mota , Conceição

1,2 POSTER SESSION 2 SESSION POSTER 115

Abstracts 116 0.020 0.035 0.098 0.014 0.024 0.024 0.063 P value P

higher score= desired c 2.14 (2.00; 2.28) 2.04 (1.90; 2.18) 7.73 (7.25; 8.21) Control (n=47) 1.06 (0.90;1.22) 1.01 (0.84; 1.17) 1.49 (1.21;1.78) 1.90 (1.68; 2.13) lower score = desired; b POSTER SESSION 2

0.80 (0.65; 0.95) 0.76 (0.61; 0.91) 8.27 (7.84; 8.71) 2.22 (2.09; 2.34) Intervention (n=58) 1.01 (0.74; 1.27) 1.92 (1.80; 2.05) 1.55 (1.35; 1.76) b

c POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE General Pediatrics Endocrinology & Growth b b Topics: Topics: b b c N 7 O I 1 T , Philip O. Ozuah , Annett-Helen Schoennagel, Ekaterina Koledova I D Patient Support Programs delivered (PSPs) via a variety of channels are important to educate, support, assist with access/ Physical activity is important (PA) for asthma management. child However, and parental illness beliefs such as fear about E

As described in the literature, NSAIDs were found to be the most common causative agent of AIN in our series. report We an Our intervention improved child and parental illness beliefs about asthma and exercise. These results may have implications for h t 9 20 Through the application of our model, we have achieved efficient and holisticPSP governance, from the planning to reporting We recruited We child-parent 109 dyads (mean age .99) 8.6 years, (SD 53% male, 80% Hispanic). Post-intervention, parents were Comparison of intervention and control groups on child and parental illness beliefs about asthma and exercise. presented as mean (95% CI); PA=physical activity. ANOVA was used to control for baseline scores. ANOVA activity. presented as mean (95% CI); PA=physical PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: a CHILD Self-Efficacy – Barriers to PA Participation PA Self-Efficacy – Barriers to Risk Perception – Stigma Risk Perception – Overall Scale Risk Perception – Stigma Outcome Expectancy – Negative Effects of PA Outcome Expectancy – Negative Effects Outcome Expectancy – Asthma Outcome Expectancy – Intent to Participate in PA PARENTS Outcome Measures interactions to active-patients, measured as a part of performance mapping, in the second was The 1.31 interacted PSPs quarter with of 2017. ID: / PO2: 107 41 ID: / PO2: 219 42 Introduction: Introduction: interesting association between maximum serum creatinine and a lengthier recovery. Ourresults do not support the empiric suspicion that intervention, 2 control). Intervention consisted of a school-wide asthma awareness event, collaboration with child’s physician to assure optimal Middle East and Africa, and ten in Asia–Pacific), including >48,000 patients and >64,000 patient interactions. Theoverall ratio of patient Materials and Methods: The main tenets of the are PSPs in place to support sound principles that are consistent with applicable laws and Merck KGaA, Darmstadt, Germany; [email protected] Marina Reznik Montefiore Medical AlbertCenter, Einstein College of Medicine, United States of America; [email protected] Materials and Methods: conducted We a pilot cluster years) with RCT in children asthma attending (7-10 4 Bronx, schools New York (2 Daniel Richter Results: Purpose: show how the To application of a best-practice governance model, including Performance Mapping, can optimize the benefit to patients from PSPs, using the specificexample of theavailablePSPs to patients taking recombinant human growth hormone(r-hGH; Poster Presentation Poster Presentation Purpose: Our objective was to assess intervention effects on asthma and exercise risk perception, self-efficacy and outcomeexpectancy in functional governance board. A global policy and supportive training for PSPs, with the mapping and tracking of all ongoing though PSPs a treatment, classroom-based and PA, asthma education for families and school personnel. Parents and children completed surveys at baseline Results: PATIENT SUPPORT PROGRAMS: GLOBAL FOOTPRINT AND BEST PRACTICE FOR PATIENTS AND HEALTHCARE AND HEALTHCARE AND BEST PRACTICE FOR PATIENTS FOOTPRINT SUPPORT PROGRAMS: GLOBAL PATIENT PROFESSIONALS EFFECTS OF A SCHOOL-BASED ASTHMA INTERVENTION ON CHILD AND PARENTAL ILLNESS BELIEFS ABOUT ILLNESS BELIEFS AND PARENTAL ON CHILD INTERVENTION ASTHMA SCHOOL-BASED A EFFECTS OF policy change to incorporate intervention components in urban schools. Conclusion: Conclusion: mitigation plan is initiated. urban schoolchildren with asthma and their parents. management, and provide care for patients and healthcare professionals on the use of medicinal products. responsibility for each is PSP assigned to a lead person in each country. In addition, all newly planned have PSPs to be approved by a cross- stages, with clear responsibilities and structures leading to accountability and there synergies. were more than As planned of June, 150 2017, more competent in overcoming barriers had to a greater PA, intention to participate were in less PA, likely to feel that exercise would have negative consequences on asthma, and were less worried overall and about asthma-related stigma (Table). somatropin). significantly less likely to believe thatexercise is harmful to asthma and were less worried about stigma than controls. Children tended to feel or ongoing worldwide. PSPs Of these, more than 40 relatedto endocrinology (four in North America, nine in Latin America, in Europe, 18 the central database, ensures the high quality of each is PSP maintained. In the event a certain defined risk threshold a exceededis PSP, by a codes and to avoid improper incentives. The meet PSPs all ethical, legal and regulatory obligations, including pharmacovigilance requirements, corticotherapy might accelerate recovery in AIN patients but larger prospective studies are needed to allow further conclusion on this. other barriers to PA. compare scores between two groups controlling for baseline. and the design and execution are fully documented. The are PSPs run under medical-governance processes, and the accountability and asthma attacks with exercise may preclude child participation. PA developed We a multifaceted school-based intervention to address this and and 6-months post-intervention to assess asthma and exercise risk perception, self-efficacy and outcomeexpectancy. was used ANOVA to Table: ASTHMA AND EXERCISE. ASTHMA

Abstracts 13.6%. Further, 4.5% to 13.6% of the children needed help to execute the related ADLs, depending on the life domain, and up to 9.1% to up and domain, life used the on depending ADLs, related the execute to help needed children 13.6% to 4.5% the of 13.6%. Further, The CHAQ.MAC investigates 34 activities of daily life(ADL) classified into 8 life domains. A statistical model was used to calculate a total CHAQ. total a calculate to used was model statistical A domains. life 8 into classified life(ADL) daily of activities 34 investigates CHAQ.MAC The Table 1: after detecting changes in intracranial calcification, cysts, lenticulostriate vasculopathy, ventriculomegaly on cranial ultrasound (CrUSS). In this this (CrUSS).In ultrasound cranial on ventriculomegaly vasculopathy, lenticulostriate cysts, calcification, intracranial in changes detecting after aids or devices. Poor QOL, as indicated by higher CHAQ.CAM scores, was associated with articular pain (p=0.003) and specific medication medication specific and (p=0.003) pain articular with associated was CHAQ.CAM scores, higher by indicated as QOL, Poor devices. or aids of Assessment 20.5%. in reported was (27.3%); stiffness morning as localization where frequent most the being knee with 43.2%, among WESTERN PROVIDENCEOFSAUDI ARABIA (p=0.043). calcification/cyst on CrUSS, 4 infants were IUGR with Cr USS changes and 7 infants had microcephaly. Congenital CMV infection was detected detected was infection CMV Congenital microcephaly. had infants 7 and changes USS Cr with IUGR were infants 4 CrUSS, on calcification/cyst chain reaction testing in body fluids. body in testing reaction chain observational study, we aimed to see if our screening of well babies mostly done for IUGR/SGA or CrUSS abnormalities pick up cCMV. up pick abnormalities CrUSS or IUGR/SGA for done mostly babies well of screening our if see to weaimed study, observational cases. Children with arthralgia and those on specific treatment are at higher risk of impaired QOL, which emphasizes the need for systematic systematic for need the emphasizes which QOL, impaired of risk higher at are treatment specific on those and arthralgia with Children cases. digital channels. clinic, inpatient ward and daycare unit in King Abdulaziz University Hospital, Jeddah, Saudi Arabia,in the period February 2017-July 2017. February period the Arabia,in Saudi Jeddah, Hospital, University Abdulaziz King in unit daycare and ward inpatient clinic, difficulties varied between 6.82% for eating and 27.3% for activities; while both dressing & grooming and hygiene was subject of difficulty for for difficulty of subject was hygiene and grooming & dressing both while 27.3% and activities; for eating for 6.82% between varied difficulties QUALITY OFLIFEINCHILDREN AND ADOLESCENTS WITHJUVENILEIDIOPATHIC RHEUMATOID ARTHRITIS IN screening for treatment adverse effects and joint pain and implementation of efficient management to improve QOL. improve to management efficient of implementation and pain joint and effects adverse treatment for screening CONGENITAL CMV– APPROACH TO SCREENINGNEONATES screening in neonates. in screening CMV of prospect the on consensus no is However, there outcomes. improve may infants affected of treatment and detection Early symptoms. Objectives: cCMV cCMV SGA is also not uniform with some units consider birth weight less than 2nd centile or less than 9th centile. Babies are also screened for cCMV cCMV for screened also are Babies centile. 9th than less or centile 2nd than less weight birth consider units some with uniform not also is SGA modified for Arab children (CHAQ-MAC). children Arab for modified Conclusion: Conclusion: Chelsea and Westminster hospital, United Kingdom; [email protected] Kingdom; United hospital, Westminster and Chelsea Children or their parents were invited for face-to-face interview, and a phone interview was done for patients who missed their appointments. their missed who patients for done was interview aphone and interview, face-to-face for invited were parents their or Children patients through nurses (12), call centres (10), or both (14); three PSPs combined these channels with a website or app, and two used only the the only used two and app, or awebsite with (12), (10), channels nurses (14); these centres both call or through PSPs combined patients three QOL showed mean CHAQ.CAM score=2.89 (75th centile=3.00).With respect of ADLs, up to 22.7% of the children complained of difficulty; and and difficulty; of complained children the of 22.7% to up ADLs, of respect centile=3.00).With (75th CHAQ.CAM score=2.89 mean showed QOL Results: Presentation Poster Presentation Poster The screening criteria for Congenital CMV are not uniform across Neonatal Units in United Kingdom. Many units screen for cCMV cCMV for screen units Many Kingdom. United in Units Neonatal across uniform not are CMV Congenital for criteria screening The Purpose: type (27.3%), followed by polyarticular (15.9%) and oligoarticular (13.6%); and 47.7% of the patients were on treatment. Pain was reported reported was (13.6%); Pain treatment. 47.7% on (15.9%) and were oligoarticular patients (27.3%), and the of type polyarticular by followed Results: King Abdull-Aziz University Hospital, Saudi Arabia; [email protected] Arabia; Saudi Hospital, University Abdull-Aziz King Shatha MAlbokhari Shatha Methods: 31.8% reported a difficulty in at least one of the 34 investigated ADLs. With respect of the life domain, the percentage of children who reported reported who children of percentage the domain, life the of respect With ADLs. investigated 34 the of one least at in adifficulty 31.8% reported Maria Chiara De Nardo De Chiara Maria MAC score (range=0 - 33; Cronbach’s alpha=0.966); with higher values indicating poorer QOL. poorer indicating values higher with alpha=0.966); Cronbach’s -33; (range=0 score MAC Methods: Baby 2 Baby Baby 1 Baby Baby 3 Baby in 3 of 170 3of in (1.8%) tested. infants included. Reason of request, and birth weight were documented. CMV was established by detection of CMV DNA by real-time polymerase polymerase real-time by DNA CMV of detection by established was CMV documented. were weight birth and request, of Reason included. integral part of all Merck PSPs worldwide. Merck all of part integral if they are born Small for Gestational Age (SGA) or with Intra uterine growth restriction (IUGR) ( Symmetrical or Asymmetrical). The criteria for for criteria The Asymmetrical). or (IUGR) (Symmetrical restriction growth uterine Intra (SGA) with Age or Gestational for Small born are they if / PO2: 43 /PO2: 236 ID: impaired quality of life (QOL). This study aimed to evaluate the QOL of children with JIA using the childhood health assessment questionnaire questionnaire assessment health childhood the using JIA with children of QOL the evaluate to aimed study (QOL). This life of quality impaired / PO2: 44 /PO2: 238 ID: Introduction: infant PO2: POSTER PRESENTATIONS: 2 SESSION Demographic characteristics, symptoms and outcome of cCMV infants cCMV of outcome and symptoms characteristics, Demographic During the study period, CMV testing was performed in 170 infants. 132 infants were IUGR/SGA, 27 infants had intracranial intracranial had infants 27 IUGR/SGA, were 132 170 in infants infants. performed was testing CMV period, study the During Forty-four children with JIA were included; male ratio=0.63; mean±SD age=9.95±5.44. Systemic-onset JIA was the most frequent frequent most the was JIA Systemic-onset age=9.95±5.44. mean±SD ratio=0.63; male included; were JIA with children Forty-four age (weeks) age Gestational Gestational 26+4 35+4 36+3 Between January 2014 and August 2017, all blood or urine samples sent for testing CMV from infants within the first 21 days were days were 21 first the within infants from CMV testing for sent 2017, samples 2014 August urine or and January blood all Between A cross-sectional study carried out among children aged≤18 years and following for JIA at the Pediatric Rheumatology outpatient outpatient Rheumatology Pediatric the at JIA for following and years aged≤18 children among out carried study Across-sectional 20 9 t Juvenile Idiopathic Rheumatoid Arthritis (JIA) is a disabling disease that associates a challenging life style and exposes to to exposes and style life achallenging associates that disease (JIA) adisabling is Arthritis Rheumatoid Idiopathic Juvenile h The application of collaborative cross-functional activities (governance, implementation, standardization, quality and safety) is an an is safety) and quality standardization, implementation, (governance, activities cross-functional collaborative of application The Approximately one-third children with JIA encounter varying levels of difficulty in ADLs, requiring assistance in 13.6% of the the in of 13.6% assistance requiring ADLs, in difficulty of levels varying encounter JIA with children one-third Approximately

E Congenital Cytomeglovirus (cCMV) is the most common congenital infection that is associated with a wide spectrum of clinical clinical of spectrum awide with associated is that infection congenital common most the is (cCMV) Cytomeglovirus Congenital D I T 1 I O 7 N , Mohammed AMuzaffer , Mohammed 1008 1825 (gr) 2423 Birthweight Birthweight Topics: Topics: , Nilüfer Güzoğlu, Prakash Desai Prakash Güzoğlu, , Nilüfer Autoimmunes, Adolescent Wellbeing Adolescent Autoimmunes, NICU < 2 25th -50 25th Centile 50th °-75 50th CONFERENCE PROGRAMME POSTER PRESENTATIONSPOSTER nd th th Thrombocytopenia Gram positive sepsis positive Gram Intracranial cyst Symmetrical IUGR Exomphalos Prematurity Symptoms Heart disease Heart Hypoglycaemia

Outcome Follow-up Died Died No treatment

POSTER SESSION 2 SESSION POSTER 117

Abstracts 118 2 , Célia Madalena 2 POSTER SESSION 2 , Carlos Sistelo 2 Department of Pediatrics. Centro Hospitalar da Póvoade 2

, Paulo Ferreira 2 , Hernâni Brito 1 POSTER PRESENTATIONS CONFERENCE PROGRAMME CONFERENCE General Pediatrics, Epidemiology Topics: , Cristina Ferreras 1 N 7 O I 1 T I D Smoking during pregnancy increases the risk of infertility; maternal and fetal adverse outcomes and postnatal problems have E

In the study, all the 3 babies identified were admitted to the neonatal unit and none of the well babies in postnatalward who Smoking prevalence during pregnancy, in our center, was Although lower than other there studies was no control (11-27%). group h t 9 20 The group included postpartum 132 women with a 30 years-old median age (corresponding of smoking to a prevalence of 5.1% license (CC BY). For citation details please refer to the online version of the book of abstractshttp://bookcitationof theonline versionthe availableFor at: of details to please referBY). license (CC eip-pediatrics-institute.ineip.org/ The abstracts in this book were originallyCommonspublishedCogentwereMedicinebookAttribution Creativeabstractsthis theThein under in PO2: POSTER PRESENTATIONS: SESSION 2 PRESENTATIONS: POSTER PO2: Department of Pediatrics. Centro Hospitalar São João, Porto-Portugal; ID: 234 / PO2: 45 Introduction: in this study, there seems to be no relation between smoking and lower gestational age or low birth weight, as described. pregnancy However, it is an important modifiable risk factor with maximum benefit in the first trimester. Marta Isabel Pinheiro Materials and Methods: Prospective analysis of medical questionnaires made to new mothers who smoked during pregnancy, whose children Poster Presentation Results: Purpose: This study aims to discover the prevalence and the habits of mothers who smoked during pregnancy at Centro Hospitalar da Póvoa primiparous, had a previous 19% abortion. On average, women started smoking cigarettes/day) at average, the (on age 10 16 and there were Conclusion: were investigated for cCMV were positive. Babies who had isolated CrUSS findings were negative. This would indicate for us to screen only was associated with a change in smoking habits. This study brings to light the need for professionals to improve their knowledge on prevention Conclusion: were born at our hospital It is between possible and July July that 2014 2017. some pregnant women hide their true smoking status. The weeks (min 32; max 41) with anweeks average 2090g; (min max 32; (min weight 41) of pregnancies at max birth 4690g; of 3147g had 5.3% some of low 17.4% weight); SMOKING DURING PREGNANCY: IMPACT ON THE NEWBORN? IMPACT PREGNANCY: SMOKING DURING mothers in this period),predominantly healthy; 95.5% of the pregnancies were well monitored and 4.5% were poorly monitored; 49.2% were symptomatic or symmetrical IUGR babies rather than all IUGR/SGA babies and based on antenatal history. smoking preconception), (13% 2.3% had a specific medical appointment and 2.3% did pharmacotherapy. The mean gestational agewas 39 1 do Varzim/Vila do Conde-Portugal and the characteristics of pregnancies and newborns. of smoking during pregnancyand the postnatal period, with specific data, appointment and, if necessary, suggest pharmacotherapy. confidentiality of the datawas ensured. complications and 3% of newborns required neonatology care. also been described. All pregnant women should be screened for the use of tobacco and it is a special occasion to promote smoking cessation; 79.5% of fathers who cigarettes/day). smoked (15 According to Fagerstrom’s test, 80.3% of mothershad a low degree of tobacco dependence, Varzim/Vila do Conde, Portugal; [email protected] 18.9% moderate18.9% and 0.8% high. During pregnancy, 66% reducedsmoking to half and stopped said 19% they were it; 57.6% advised to stop

Abstracts CONFERENCE PROGRAMME 2017 SPEAKERS / MODERATORS 119 9th EDITION

SPEAKERS / MODERATORS INDEX

Speaker Page Speaker Page

AAGJE IEVEN 11, 42 JERZY B. STARZYK 6, 27

ADRIANA BABAN 5, 25 JOAN-CARLES SURIS 3, 5, 6, 8, 9, 10, 11, 24, 27, 29, 34, 36, 41, 44

ALAN D. ROGOL 6, 10, 27, 40 JO INCHLEY 3, 5, 11, 24, 44

ALISON JOHNS 8, 10, 11, 35, 41, 43, 45, 46 JOY LADURNER 11, 42

ANDREA POLOVINA 9, 38 JUDIT VILLOSLADA 5, 9, 26, 27, 36

ANDREW BUSH 10, 11, 40, 44 JUTTE VAN DER WERFF TEN BOSCH 10, 41

ANDREW RIORDAN 5, 9, 25, 37 KENNETH J. MACK 8, 36

ANGELO PIETROBELLI 6, 28 KURT WIDHALM 6

AZIZ KOLEILAT 7, 30 KURT WIDHALM 7, 28, 30

BARBARA KUNZ 8, 36 LAURA OFFUTT 5, 25

BASIL PORTER 7, 31 LEANNE GOH 8, 9, 35, 37

BOB SALLIS 7, 8, 32, 36 LUISA DESANCTIS 8, 34

CARL-ERIC FLODMARK 6, 28 LUIS MORENO AZNAR 6, 28 Speakers / Authors Index

CATHERINE WEIL-OLIVIER 9, 37 MARIA SZARRAS-CZAPNIK 10, 40

CHRISTINA AKRE 5, 7, 8, 9, 27, 32, 36 MARK BEATTIE 5, 6, 7, 25, 29, 30

CLAUDIA STEFANUTTI, MD, PHD 7 MICHAEL FITZGERALD 6, 29

COLIN MICHIE 8, 34 MITCH BLAIR 8, 34

COURTNEY KIPPS 7, 8, 32, 36 NICK WEBB 6, 28, 29

CURT HAGQUIST 5, 25 PATRICIO AGUIAR 9, 38

DAMIAN ROLAND 9, 11, 40, 42 PEGGY MCMANUS 8, 34

DAPHNE HOLT 8 PENNY SALT 8, 9, 35, 37

DASHA NICHOLLS 9, 39 RICHARD WIDMER 8, 34

DAVID SALISBURY 8 ROBERT STEINFELD 8, 33

DEBBY BOGAERT 5, 26 ROLAND HENTSCHEL 11, 43

DIRK VAN GYSEL 8, 36 ROSEMARIE FELDER-PUIG 7, 31

DOUG PARKIN 8, 10, 11, 35, 41, 43, 45, 46 ROY K. PHILIP 5, 6, 11, 26, 29, 42

ELENA MOYA 9, 37 SEBASTIAN IONESCU 5, 26

ELLEN KLEMERA 11, 42 SIMON KROLL 5, 26

FARASAT ZAMAN 6, 27 SOPHIA KALLIS 8, 9, 35, 37

FATIMAH SANIA 51 STEPHEN ALLEN 5, 26

FRANCESCO RAIMONDI 5, 9, 26, 38 SUSANNE KIRCHER 9, 39

FRANCOIS EYSKENS 9, 38 SUSANNE LAU 6, 29

GERALD HUMPHRIS 7, 31 SVETISLAV POLOVINA 8, 36

GIJS ELSHOUT 5, 25 TERENCE STEPHENSON 3, 5, 8, 11, 24, 42, 44

GIOVANNI CIANA 9, 38 TIM CHEETHAM 6, 10, 27, 40

GIULIA PAIOLA 52 TORSTEN UHLIG 11, 43

GIUSEPPE INDOLFI 9, 39 TORUN MARIE VATNE 7, 31

GLENDA SOBEY 8, 33 UMA RAMASWAMI 8, 9, 10, 33, 38, 41

IMTI CHOONARA 9, 11, 39, 42 VASILICA PLAIASU 10, 41

INGE LISSAU 6, 28 YVAN VANDENPLAS 8, 9, 35, 39

IOANNA GRIVEA 7, 32 CONFERENCE PROGRAMME 2017 Authors 120 9th EDITION

AUTHORS INDEX

Author Session Page Author Session Page

A Ayres Pereira, Isabel OP3:2, PO1:2 63, 80 Abadesso, Clara OP4:2 69 Azevedo, Margarida PO2:33 112 Abdel-Karim, Tasneem OP4:10 73

Speakers / Authors Index / Authors Speakers B Abdelrahman, Hatim PO1:18, PO2:24 88, 109 Ba sharahil, Najla PO1:19 88 Abdulrahman, Hatim Μohamed OP2:7 60 Bae, Chong-Woo PO1:4 81 Abeysekera, Mithila PO2:11 103 Baldwin, Lydia PO2:2 99 Abi Fares, Georges OP4:7 72 Bandara, Priyantha PO2:11 103 Abreu, Mariana PO1:20 89 Baptista, Cristina PO2:14 104 Adedokun, Comfort OP1:7 54 Barbosa, Célia OP5:10 79 Adikaram, Shamini GS OP2:6 59 Barsan Kaya, Tugba OP1:2 51 Agosti, Massimo OP1:4 52 Baška, Tibor PO1:41 98 Aguiar, Clarisse OP2:5 59 Begou, Olga PO1:23 90 Aguiar, Liza OP2:5 59 Belanger, Richard OP3:1, PO2:20 63, 107 Ahmed, Shahnawaz OP2:12, PO2:32 62, 112 Bera, Liana PO1:35 95 Akanayeva, Alnura PO2:12 104 Berbel, Evelyn PO2:26 110 Akman Akyurt, Yezdan OP3:4 64 Berthelot, Simon OP3:1, PO2:20 63, 107 Akubue, Nnaemeka PO1:3 81 Bianchi de Aguiar, Benedita PO2:33 112 Akyurt, Cüneyt OP3:4 64 Bianchi de Aguiar, Benedita Sousa PO1:36 96 Al Saleh, Abdullah Saleh PO1:42 98 Amaral Albokhari, Shatha Mohammed OP1:5, PO2:43 53, 117 Bica, Catalina PO2:15 105 Alemán-Díaz, Aixa Y. PO2:38 114 Bildirici, Yasar OP1:2 51 Alhammadi, Ahmed OP4:10, PO1:18, PO2:24 73, 88, 109 Bjerre, Jesper OP3:10, OP4:5 67, 70 Alimhanova, Gulshat PO2:8 102 Bláhová, Květa PO1:32 94 Alkan, Gülsüm PO1:14 86 Blankenship, Jeremy PO1:12 85 AlOjaimi, Mode OP4:7 72 Boberová, Zuzana PO1:41 98 Álvaro, Montserrat OP1:9 55 Bogdanova, Natalia PO1:25 90 Amalia, Pustika OP3:9 66 Bogdanović, Radovan PO1:16 87 Amer, Ahdi OP3:3 64 Bondarenko, Dmitriy PO2:8 102 Amin, Md. Ruhul OP4:4 70 Borges, Teresa PO1:33 95 Arambepola, Carukshi PO2:11 103 Bouritius, Hetty OP1:4 52 Araújo, Ana Rita OP3:6, PO1:29 65, 93 Braga, Raquel OP5:6 77 Arora, Rohit OP5:4 76 Bralić, Irena OP4:8 73 Arora, Sunaina OP5:4, PO1:24 76, 90 Branaco, Mariana PO1:29 93 Arsenault-Blanchard, Laurence OP3:1, PO2:20 63, 107 Brants, Ilona PO1:10 84 Asmar, Basim OP3:3 64 Bravio, Ivan OP4:2 69 Atapattu, Navoda OP2:6 59 Brito, Hernâni PO2:21, PO2:45 108, 118 Aydemir, Ozge OP1:2 51 Brooks, Rivka PO2:9 102 CONFERENCE PROGRAMME 2017 Authors 121 9th EDITION

Author Session Page Author Session Page

Bukovský, Petr PO1:32 94 de Sanctis, Luisa OP2:1 57 Bulegenova, Minira PO2:7, PO2:8 101, 102 Desai, Prakash PO2:44 117 Buslovich Khayumov, Svetlana PO1:10 84 Deshaies Poliquin, Karina OP3:1, PO2:20 63, 107 Butterworth, Erin OP1:10 55 Dilshan, Prasanna PO2:11 103 Dinescu, Sorin PO2:15 105 C Dinleyici, Meltem OP1:2 51 Campbell, Kanday PO1:12 85 Dissanayake, Buddhini S PO2:11 103 Cancela, Jorge OP1:6 53 Dodd, James Keith OP3:10, OP4:5 67, 70 Cândido, Cristina OP4:12 74 Drosou, Vasiliki PO1:23 90 Cardoso, Helena PO1:33 95 Duarte, Maria Ema OP2:5 59 Carman, Kursat Bora OP1:2 51 Duarte, Ximo OP4:2 69 Carrion, Victor Gerard OP3:7 66 Dzielska, Anna PO2:35 113 Carvalho, Catarina PO1:33 95

Carvalho, Irene PO2:23 108 E Carvalho, Joana PO2:14 104 Edwards, Lauren PO2:34 113 Carvalho, Rita Vieira OP4:2 69 Efstathiou, Nikolaos G. PO1:23 90 Castro-Correia, Cíntia PO1:20 89 Eisenhut, Michael PO1:30, PO2:5 93, 101 Centauri, Cynthia OP3:9, PO2:13 66, 104 El Baki, Mohammad Ahsanulah OP4:4 70 Cetemen, Ayşen OP3:4 64 El Khoury, Joey OP4:7 72 Chang, Yu-Jun OP1:12, OP4:6, PO1:28, 57, 71, 92, 105 El Makki, Ahmed PO1:19 88 PO2:16

Elghawaby, Ahmed PO2:24 109 Speakers / Authors Index Chen, Chun-Yu OP1:12, OP4:6, PO1:28, 57, 71, 92, 105 PO2:16 Elhussien, Manal Mohamed Khalid OP2:8 60 Cherkaeva, Asya PO1:39 97 Elsharkawy, Adel PO2:12 104 Choi, Yong-Sung PO1:4 81 Escobar, Carlos OP4:2 69 Cholidis, Nickolaos OP1:10 55 Essam, Ahmed PO1:18 88 Chung, Sung-Hoon PO1:4 81 Esteves, Ana Luísa PO1:38 97 Cismaru, Liana PO2:15 105 Evstratenko, Alla PO1:39 97 Coelho, Rafaela OP2:5 59 Ewert, Peter OP2:10, PO2:18 61, 106 Contreiras, Marta OP4:11 74 F Correia-Costa, Liane PO2:40 115 Fachrianzy, Daeng OP1:1 51 Correia, Cintia PO2:10 103 Fadous Khalife, Marie Claude J. OP4:7 72 Corvaglia, Luigi Tommaso OP1:4 52 Falcão, Inês PO1:33 95 Costa, Ana Margarida PO2:14 104 Faria, Carolina PO2:23 108 Costa, Mariana OP5:10, PO2:36 79, 114 Faruque, Abu Syed Golam OP2:12, PO2:32 62, 112 Costa, Miguel PO1:36 96 Felder-Puig, Rosemarie OP2:4 58 Costa, Teresa PO2:40 115 Fencl, Filip PO1:32 94 Cunha, Joaquim PO1:21 89 Fernandes, Ana Paula OP2:11 61 Cupal, Suzanne PO1:12 85 Fernandes, João Paulo OP5:10 79 Currie, Candace PO2:38 114 Ferrão, Anabela OP4:11 74 Ferraz de Liz, Catarina OP5:6, PO1:21 77, 89 D Dal Pos, Valter OP2:1 57 Ferreira, Ana Maria PO2:33 112 Dalal, Ilan PO1:10 84 Ferreira, João Soares OP2:5 59 Dankulincová Veselská, Zuzana PO1:41 98 Ferreira, Nuno PO1:21 89 Daviko Levi, Bat-Hen Annie PO1:10 84 Ferreira, Paulo PO2:21, PO2:45 108, 118 de Carvalho Vaz, Ana OP5:10, PO2:36 79, 114 Ferreira, Sérgio OP4:2 69 De Nardo, Maria Chiara PO2:44 117 Ferreira, Sofia Helena PO1:20, PO2:39 89, 115 Ferreras LLamazares, Cristina PO2:21, PO2:45 108, 118 CONFERENCE PROGRAMME 2017 Authors 122 9th EDITION

Author Session Page Author Session Page

Figueiredo, António OP4:2 69 Holzer, Naama PO2:9 102 Filter, Marilyn PO1:12 85 Hosbay, Zeynep PO1:9 83 Fischer, Howard OP3:3 64 Huang, Fang-Liang PO2:22 108 Folqué, Maria del Mar OP1:9 55 Hudečková, Henrieta PO1:41 98 Fonseca, Sara OP2:11 61 Humphris, Gerald PO2:38 114 Fontoura, Manuel PO1:20 89 Husárová, Daniela PO1:41 98 Foster, Andrew OP1:10 55 I Frasquilho, Diana OP2:3 58 Ichihashi, Ko OP5:2 75 Freitas, Joana PO1:33 95 Išpanović, Veronika PO1:16 87 Fried, Elchanan PO2:9 102 Istatik, Yun OP1:1 51

G Iurian, Sorin Ioan PO1:35 95 Gagnon, Josée-Anne OP3:1, PO2:20 63, 107 J

Speakers / Authors Index / Authors Speakers Gajewski, Jakub PO2:6 101 Jacob, Sylvia PO1:20 89 Galanis, Petros OP2:13, PO1:22 62, 89 Jasinge, Eresha OP4:9, PO1:5 73, 82 Ganapathy, Sashikumar PO2:31 112 Jayasekera, Hasika Dilhani OP2:6 59 Garcia Puig, Roger PO2:26 110 Jørgensen, Finn Stener OP3:10, OP4:5 67, 70 García-Moya, Irene PO2:38 114

Gaspar de Matos, Margarida OP2:3 58 K Gavine, Anna PO2:38 114 Kabir, ARM Luthful OP4:4 70 Gheonea, Cristian PO2:15 105 Kachurina, Dilyara PO2:7 101 Giambona, Antonino OP4:1 68 Kadiric-Kasap, Sanda PO2:37 114 Gika, Helen G PO1:23 90 Kaemmerer, Harald OP2:10, PO2:18 61, 106 Giner, María Teresa OP1:9 55 Kallappa, Chetana PO2:2 99 Glazkin, Leonid OP3:12 68 Kamalaporn, Harutai PO1:7 83 Gonçalves, Daniel PO1:20, PO2:10 89, 103 Kamiyoshi, Naohiro PO2:27 110 Gonçalves, Vera OP3:6, PO1:29, PO2:4, 65, 93, 100, 114 Karplus, Gideon PO1:10 84 PO2:36 Kaukenbaeva, Gulnara PO2:7 101 Gordon, Yadira OP1:9 55 Keleş, Sevgi PO1:14 86 Gorito, Vanessa Oliveira OP4:12, PO2:14 74, 104 Kendaragama, Lakshika OP2:6 59 Gozaydinoglu, Suheda OP3:11 67 Kepenek-Varol, Busra OP1:11, OP4:3, PO1:9 56, 69, 83 Guardiano, Micaela PO1:40, PO2:10 97, 103 Khalifa, Mohamed sobhy OP2:7 60 Guedes, Sandra OP1:6 53 Khan, Muhammed PO2:2 99 Guimarães, Hercilia OP5:8 78 Kilic Yildirim, Gonca OP1:2 51 Gurses, Hülya Nilgün OP1:11, OP4:3, OP3:5, 65, 69, 77, 86 PO1:15 Kim, Cho Hee PO1:6 82 Güven, Şirin OP3:4 64 Kim, Hye-Young PO1:37 96 Güzoğlu, Nilüfer PO2:44 117 Kim, Kwanghoon PO1:37 96 Kim, Min Sun PO1:4, PO1:6 81, 82 H Kleszczewska, Dorota PO2:6, PO2:35 101 Habib, Rahat Bin OP4:4 70 Kodjebacheva, Gergana D. PO1:12 85 Hager, Alfred OP2:10 61 Koledova, Ekaterina OP1:6, PO2:42 53, 116 Haque, Nazmul OP4:4 70 Kosenkova, Tamara PO1:25 90 Hasanova, Nillifer PO2:12 104 Kragić, Katija OP4:8 73 Hassan, Manasik OP2:7, PO1:18, PO1:19, 60, 88, 109 Krauß, Anna PO2:18 106 PO2:24 Kugo, Masaaki PO2:27 110 Hendaus, Mohamed OP4:10 73 Kurilina, Tetiana PO1:17 87 Herath, Amali N OP2:6 59 Kuruppu, Suran PO2:11 103 Hilliker, Laurel PO1:12 85 CONFERENCE PROGRAMME 2017 Authors 123 9th EDITION

Author Session Page Author Session Page

Kusainov, Daniyar PO2:8 102 Malik, Nada OP2:8 60 Kütük Yılmaz, Pınar PO2:3 100 Malkowska-Szkutnik, Agnieszka PO2:6, PO2:35 101, 113 Kutuk, Yilmaz PO1:15 86 Malouf, Issam OP4:7 72 Mandelgeim, Olga PO1:10 84 L Mangunatmadja, Irawan OP3:9 66 Laghrouz, Bassil PO1:19 88 Manso, Rita OP4:2 69 Laizane, Marta PO1:13 85 Mansour, Marwa OP4:10 73 Laksmi, Eka OP3:9 66 Mantas, Pedro OP2:5, PO2:17 59, 106 Leal, Isabel OP2:2 58 Manuyakorn, Wiparat PO1:7 83 Leão, Miguel PO1:20, PO1:40 89, 97 Marceau, Alexandre OP3:1, PO2:20 63, 107 Lee, Jang Hoon PO2:19 107 Mardare, Roxana PO2:5 101 Leenskjold, Stine OP3:10, OP4:5 67, 70 Marinho, António Pedro OP5:10, PO1:29, 79, 93, 114 Leitão, Cátia OP3:2, OP5:1, OP5:7, 63, 75, 78, 80, 91, 97 PO2:36 PO1:2, PO1:27, PO1:38 Martins Guedes, Filipa OP5:6 77 Leite, Ana Luísa OP5:1, PO1:38 75, 97 Martins, Alexandra PO1:36, PO2:33 96, 112 Leite, Maria Isabel Bento Ayres OP5:1, PO1:38 75, 97 Pereira Martins, Ana Luísa OP2:5 59 Li, Xiaoming OP3:3 64 Martins, Francisca OP3:6, PO2:4 65, 100 Lim, Chun PO1:30 93 Martins, Sandrina PO2:4 100 Lima, Sofia Costa OP4:11 74 Martins, Vânia OP4:12 74 Lista, Gianluca OP1:4 52 Marujo, Margarida PO2:17 106

Litosh, Badim PO2:7 101 Matarazzo, Patrizia OP2:1 57 Speakers / Authors Index Lopes, Aldina PO2:17 106 Matos, Margarida Gaspar OP2:2 58 Lopes, Ana OP5:7 78 Mazur, Joanna PO2:35 113 Loseva, Ksenia PO1:1 80 Medise, Bernie Endyarni OP3:9 66 Lourenço, Lara PO2:10 103 Megremi, Amalia PO1:8 83 Lozano, Jaime OP1:9 55 Meirson, Gila PO1:10 84 Lozanović, Dragana PO1:16 87 Melo, Sara PO1:27 91 Ludwig, Thomas OP1:4 52 Mendes, Catarina PO1:33 95 Lytzen, Rebekka OP3:10, OP4:5 67, 70 Mikhovich, Mikhail OP3:12 68 Milidrag, Marica PO1:16 87 M Mittal, Manish OP5:4 76 Maarafiya, Muna PO1:18, PO2:24 88, 109 Mlaco Hrkic, Mirna PO2:37 114 Maayan, Channa PO2:9 102 Moeda, Sofia OP4:11 74 Macedo, Conceição PO1:38 97 Mohammed, Fatma Sharhabeel OP2:8 60 Machado, Ângela PO1:21 89 Margani Machado, Maria Céu OP2:2 58 Mollah, Md. Abid Hossain OP4:4 70 Machinena, Adrianna OP1:9 55 Moncada, Alice OP4:1 68 Maciorkowska, Elzbieta PO1:11 84 Moniz, Marta OP4:2 69 Madalena, Célia PO2:21, PO2:45 108, 118 Moreira Echeverria, Ana PO2:26 110 Maduekwe, Ogochukwu PO1:3 81 Morgan, Antony PO2:38 114 Maduemem, Kene Ebuka OP1:7, PO1:3 54, 81 Mota, Conceição PO2:40 115 Magalhaes, Augusto PO2:23 108 Mugarab Samedi, Veronica PO2:12 104 Magalhães, Nuno OP2:5 59 Mukherkee, Anindya PO2:34 113 Maia, Ana OP2:11, PO2:23 61, 108 Mulder, Kelly A OP1:4 52 Maier, Gunter PO2:29 111 Mulia, Dwi OP1:1 51 Maio, Inês PO2:40 115 Muñoz, Antonio OP1:4 52 Majumder, Jasim Uddin OP4:4 70 Mustafa, Amira PO1:19 88 Muzaffer, Mohammed A PO2:43 117 CONFERENCE PROGRAMME 2017 Authors 124 9th EDITION

Author Session Page Author Session Page

Myojin, Shota PO2:27 110 Phillips, Marianne PO1:30 93 Piacentini, Giorgio OP1:3 52 N Piccione, Maria OP4:1 68 Nagdyman, Nicole OP2:10, PO2:18 61, 106 Pickard, Jack PO2:5 101 Náhlovský, Jiří PO1:32 94 Pieper, Lars PO2:18 106 Nallagonda, Srinivas OP5:5 77 Pietrobelli, Angelo OP1:3 52 Navero, Juan L. P. OP1:4 52 Pinheiro, Marta Isabel PO2:21, PO2:45 108, 118 Nebel, Kathrin PO2:18 106 Pinto, Helena PO2:39 115 Nechaeva, Irina PO1:39 97 Piquer, Mònica OP1:9 55 Neidenbach, Rhoia Clara OP2:10, PO2:18 61, 106 Pişkin, Metin PO2:3 100 Neo, Wen Yang PO2:31 112 Plaza Martín, Ana María OP1:9 55 Nêveda, Rui OP3:6 65 Porcel, Rocio OP1:4 52 Nicolas, Georges OP4:7 72 Powell, Rebecca Jane Fiona PO2:28 110

Speakers / Authors Index / Authors Speakers Nogueira, Mayara OP5:8 78 Putera, Ikhwanuliman OP1:1 51 Noureldein, Mona OP5:5, PO2:5 77, 101 Putri, Nina Dwi PO2:13 104 Nunes, Pedro OP4:2 69 Pysariev, Andrii PO1:17 87 Nunes, Renato PO1:40 97

Q O Quek, Samuel En Ci PO2:31 112 Oberhoffer, Renate OP2:10, PO2:18 61, 106

Oliveira, Ana Cristina PO1:2 80 R Oliveira, Joana A. OP4:11 74 Ramalho, Helena OP3:6 65 Oliveira, Maria João PO1:33 95 Rangel, Maria Adriana OP5:7, PO1:27 78, 91 Oliveira, Raquel OP5:10 79 Reis e Melo, Ana OP5:8, PO2:10 78, 103 Osório, Eduarda OP5:1, PO1:2 75, 80 Reisli, Ismail PO1:14 86 Özkan, Yasemin PO2:3 100 Rey y Formoso, Vicente PO2:23 108 Ozpinar, Aysel OP1:8 54 Reznik, Marina PO2:41 116 Ozuah, Philip O. PO2:41 116 Ribeiro-Mourão, Francisco OP3:6, PO1:29, PO2:4, 65, 93, 100, 114 PO2:36 P Ribeiro, Andreia OP3:2, OP5:1, OP5:7, 63, 75, 78, 80, 91, 97 PO1:2, PO1:27, PO1:38 Paiola, Giulia OP1:3 52 Richter, Daniel PO2:42 116 Paiva de Magalhaes, Tiago OP2:11, PO2:23 61, 108 Augusto Rigas, Angelos OP2:13, PO1:22 62, 89 Pandee, Uthen PO1:7, PO2:30 83, 111 Riggioni, Carmen OP1:9 55 Papadouri, Thalia PO1:22, OP2:13 62, 89 Rizky, Syandriagus OP1:1 51 Park, Moon Sung PO2:19 107 Rocha, Sara OP2:5, PO2:17 59, 106 Passas, Armanda PO1:27, OP5:7 78, 91 Rodrigues, Hugo PO2:36 114 Pecoraro, Luca OP1:3 52 Rodrigues, Joana PO2:33 112 Peixoto, Sara OP4:12 74 Rodriguez-Herrera, Alfonso OP1:4 52 Pena, Teresa OP5:7 78 Roekworachai, Koonkoaw PO1:7 83 Pereia, Sandra PO1:20 89 Roh, Youngeun PO1:37 96 Pereira, Ângela OP5:10 79 Rosário, Marta OP5:8, PO1:40 78, 97 Pereira, Cátia OP1:9 55 Rosenfeld, Natan PO2:9 102 Pereira, Isabel OP5:7, PO1:27 78, 91 Roszko-Kirpsza, Izabela PO1:11 84 Pereira, Magalys PO1:36 96 Rudić, Nenad PO1:16 87 Pereira, Susana OP5:7 78 Ruivo, Rosário OP4:2 69 Petersen, Olav Bjørn OP3:10, OP4:5 67, 70 Rumba-Rozenfelde, Ingrida PO1:13 85 Philippon, Daniel OP3:1, PO2:20 63, 107 Ruslyaraz, Ruslyaraz OP1:1 51 CONFERENCE PROGRAMME 2017 Authors 125 9th EDITION

Author Session Page Author Session Page

Rygl, Michal PO1:32 94 Stanescu, Ligia PO2:15 105 Stang, A PO2:12 104 S Stará, Veronika PO1:32 94 Safran, Ertugrul OP3:5 65 Štefanová, Eliška PO1:41 98 Sahin, Ozlem Naciye OP1:8 54 Stylianou-Riga, Paraskevi OP2:13, PO1:22 62, 89 Sakkal, Josephine OP4:7 72

Salah, Elmuntasir Taha Mohamed OP2:8 60 T Salonna, Ferdinand PO2:6 101 Tavares, Hugo PO1:38 97 Salzano, Emanuela OP4:1 68 Tavchioska, Gabriela OP2:9, PO1:26 60, 91 Samaranayake, Dulani OP4:9, PO1:5 73, 82 Taylor, H. Gerry OP5:3 76 Samaranayake, Dulani BDL OP2:6 59 Teixeira, Ana PO2:39 115 Samedi, Anar PO2:12 104 Teles Silva, Cláudia OP5:8 78 Sampaio, Mafalda PO1:20 89, 103 Teles, Ariana OP3:6, PO2:4 65, 100 Sanftenberg, Linda PO2:10 106 Tenente, Joana OP3:2 63 Sania, Fatimah PO2:18 51 Tenero, Laura OP1:3 52 Santos Silva, Jorge OP1:1 78 Tessaris, Daniele OP2:1 57 Santos, Helena OP5:8 78, 91 Theodoridis, Georgios PO1:23 90 Santos, Paulo OP5:7, PO1:27 104 Theodorou, Mamas OP2:13, PO1:22 62, 89 Santos, Teresa Cristina PO2:14 58 Thull-Freedman, J PO2:12 104 Sarafidis, Kosmas OP2:2 90 Tiwari, Lokesh PO1:24 90

Satari, Hindra Irawan PO1:23 104 Torrado, Inês OP4:12 74 Speakers / Authors Index Saulite, Ieva PO2:13 85 Tridjaja, Bambang OP3:9 66 Schelling, Jörg PO1:13 106 Tryanni, Vania OP1:1 51 Schmitt, Denise PO2:18 112 Tsekoura, Effrossine OP3:8, PO1:1 66, 80 Schoennagel, Annett-Helen PO2:33 116 Tuncer, Deniz OP1:11, PO1:15 56, 86 Schwarz, Max PO2:42 106 Turganova, Elena PO1:25 90 Seidel, Lavinia PO2:18 106 U Seitz, Ulrich PO2:18 61 Ucgun, Hikmet OP4:3 69 Sener, Gul OP2:10 99 Umego, Ekene PO1:3 81 Senevirathne, Tharika N PO2:1 59 Unal Eren, Kamer OP1:11, OP3:5, PO2:1 56, 65, 99 Serdar, Muhittin OP2:6 54 Unsal, Ibrahim OP1:8 54 Serteser, Mustafa OP1:8 54 Urkmez, Berna OP3:11 67 Shatha Mohammed Albokhari OP1:8 53 Useini Avdi, Teuta OP2:9 60 Shekenova, Anar PO2:8 102

Shing, Hoi OP5:5, PO2:5 77, 101 V Siddiq, Khaled PO1:18, PO2:24 88, 109 Valongo, Carla PO1:27 91 Silva, Carmén PO1:40 97 Vavilov, Alexander PO1:39 97 Silva, Gorett OP5:8 78 Vavilova, Vera PO1:39 97 Simões, Celeste OP2:2 58 Vaz, Ana PO2:4 100 Sistelo, Carlos PO2:21, PO2:45 108, 118 Vaz, Ana Luísa OP3:6 65 Sokal Jovanović, Ljiljana PO1:16 87 Vecchio, Davide OP4:1 68 Solanki, Pratik OP1:10 55 Vejlstrup, Niels OP3:10, OP4:5 67, 70 Solis Baltodano, Mayela PO2:26 110 Venz, John PO2:18 106 Somisetty, Sateesh OP5:5 77 Vidanapathirana, Dinesha Maduri OP4:9, PO1:5 73, 82 Søndergaard, Lars OP3:10, OP4:5 67, 70 Viegas, Sónia OP3:2 63 Song, In Gyu PO1:4, PO1:6 81, 82 Vieira, Ana PO1:27 91 Soubasi, Vasiliki PO1:23 90 Vieira, Isabel PO1:40 97 CONFERENCE PROGRAMME 2017 Authors 126 9th EDITION

Author Session Page Author Session Page

Vila Real, Marta OP3:2 ,PO1:2 63, 80 Y Vrdoljak, Javor OP4:8 73 Yadav, Pankaj OP5:4 76 Vrdoljak, Ozren OP4:8 73 Yakovleva, Inna PO1:31 94 Vučković, Stanislava PO1:16 87 Yang, Wen-Chieh OP1:12, OP4:6, OP5:9, 57, 71, 79, 92, 95 PO1:28, PO1:34 W Yıldız, Aysel OP3:5 65 Wassef, Reem Emad El-Deen OP4:10 73 Yu, Juyoun PO1:6 82 Watson, Liam PO1:30 93 Wickramasinghe, Pujitha OP2:6, OP4:9, PO1:5, 59, 73, 82 59, 103 Z PO2:11 Zajeganović Jakovljević, Jelena PO1:16 87 Wiener, Hila PO1:10 84 Živić, Helena PO2:25 109 Wu, Han-Ping OP1:12, OP4:6, PO1:28 57, 71, 92 Znamenska, Tetiana PO1:17 87 Wu, Tsung-Hua PO2:22 108 Speakers / Authors Index / Authors Speakers CONFERENCE PROGRAMME 2017 NOTES 127 9th EDITION

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