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TEF Polyclonal Antibody

Catalog No. E-AB-33065 Reactivity H,M,R Storage Store at -20℃. Avoid freeze / thaw cycles. Host Rabbit Applications WB,IHC-p,ELISA Isotype IgG

Note: Centrifuge before opening to ensure complete recovery of vial contents.

Images Immunogen Information Immunogen Synthesized peptide derived from the C-terminal region of human TEF Swissprot Q10587 Synonyms TEF,KIAA1655,Thyrotroph embryonic factor

Western Blot analysis of Jurkat cells Product Information with TEF Polyclonal Antibody. Calculated MW 33kDa Observed MW 37kDa Buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. Purify Affinity purification Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Background This gene encodes a member of the PAR (proline and acidic amino acid- rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.TEF (TEF, PAR BZIP Transcription Factor) is a Protein Coding gene. Diseases associated with TEF include Ametropic Amblyopia and Trachea Leiomyoma. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is HLF.

For Research Use Only Focus on your research Thank you for your recent purchase. If you would like to learn more about antibodies,please visit www.elabscience.com. Service for life science Applications:WB-Western Blot IHC-Immunohistochemistry IF-Immunofluorescence IP-Immunoprecipitation FC-Flow cytometry ChIP- Chromatin Immunoprecipitation Reactivity: H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh- Sheep Pg-Pig Z-Zebrafish X-Xenopus C-Cow.