01/21/17 CURRICULUM VITAE

ANJULIKA CHAWLA, MD

Business or Mailing Address: Division of Pediatric /Oncology Hospital 593 Eddy Street Providence, RI 02903

Business Telephone Number: (401) 444-5171 FAX Number: (401) 444-8845 Email Address: [email protected]

EDUCATION

9/1982-5/1985 Vermont Academy, Saxtons River, VT

9/1985-5/1989 Wesleyan University, Middletown, CT BA in Molecular Biology, , Chemistry

1/1990-5/1990 George Washington University, Washington, DC Graduate course in Molecular Biology

9/1991-6/1995 : University of Vermont, College of Medicine, Burlington, VT

POSTGRADUATE TRAINING

7/1995-6/1998 Residency: Tulane Medical Center, New Orleans, LA Pediatrics Served as Program Delegate (1996-97) and then Assistant District Coordinator for the AAP

7/1998-6/2001 Fellowship: University of California, San Francisco, San Francisco, CA Division of Pediatric Hematology/Oncology

POST GRADUATE HONORS AND AWARDS

1997 Chairman’s Award for Excellence in Academic Medicine Tulane University Medical Center, New Orleans, Louisiana

2003 Nominated for Pediatric Faculty of the Year Hasbro Children’s Hospital

2007-08 Awarded Dean’s Excellence in Teaching Award Warren Alpert Medical School at

2009 Awarded Brite Lite Award, Hasbro Children’s Hospital

PROFESSIONAL LICENSES AND BOARD CERTIFICATION

12/95-12/98 Louisiana State License, ID number 022573 5/99-current California State License, ID number A67680 (currently inactive) 10/1-current Rhode Island State License, ID number 10715 3/04 – current Massachusetts State License, ID number 9/98 Pediatric Board Certified, Certificate No. 063926 (completed recertification 10/2016) 11/04 Board Certified Pediatric Hematology/Oncology (completed Recertification 10/2015)

ACADEMIC APPOINTMENTS

03/2000-06/2001 Clinical Instructor in Pediatrics San Francisco General Hospital UCSF, San Francisco

10/2001-present Assistant Professor of Pediatrics Brown Medical School

10/2011 Associate Professor or Pediatrics, Clinician Educator Warren Alpert School of Medicine at Brown University

DEPARTMENT OF PEDIATRIC TEACHING ROLES

07/03 – 07/09 Program Director Residency Elective and Selective Hasbro Children’s Hospital

5/06 – 09/2014 Program Director Fellowship, Pediatric Hematology/Oncology Hasbro Children’s Hospital

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2006 – 2011 Pediatric Fellowship Executive Committee Co-chair 2006-2008 Hasbro Children’s Hospital

2004 –05, Resident Recruitment Committee 2007-2017 Department of Pediatrics Warren Alpert Medical School at Brown University

2002-2016 Pediatric Resident Advisor 8 advisees Department of Pediatrics Warren Alpert Medical School at Brown University

WARREN ALPERT SCHOOL OF MEDICINE TEACHING ROLES

2005,2007,2009, Community Health Clerkship Faculty Mentor: Biomed 540 2012 5 mentees Warren Alpert Medical School at Brown University

07/03 - 07/09 Program Director Medical Student Subinternship in Pediatric Hematology/Oncology Biomed 468 Hasbro Children’s Hospital

07/03 - 07/09 Program Director Medical Student Elective in Pediatric Hematology/Oncology Biomed 451 Hasbro Children’s Hospital

2006-current On Doctoring Faculty Mentor: Biomed 360 7mentees Warren Alpert Medical School at Brown University

2004-current Longitudinal Clinic Mentor: Biomed 461 8 mentees Warren Alpert Medical School at Brown University

2004-current Lecturer, Integrated Hematology: Biomed 350 Disorders of Hemoglobin: Sickle Cell Disease and Thalassemia Warren Alpert Medical School at Brown University

2009–2011 Lecturer, Integrated Hematology: Biomed 350 Porphyria Warren Alpert Medical School at Brown University

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2006-current Lecturer, Fetal medicine course: Biomed 572 Hemoglobinopathies and in utero management. Warren Alpert Medical School at Brown University

2016-2017 Faculty Independent study: Hai An Pham Brown University

HOSPITAL APPOINTMENTS

9/2000-6/2001 Physician, Department of Pediatrics San Francisco General Hospital

9/2001- current Associate Physician, Division of Pediatric Hematology/Oncology /Hasbro Children’s Hospital

1/2003- current Program Director Director Sickle Cell/Thalassemia Program, Hasbro Children’s Hospital

4/05 – 6/10 Medical Director Max All Stars Palliative Care Program

10/2013-present Interim Director Division of Pediatric Hematology/Oncology

10/2013-present Clinic Director Division of Pediatric Hematology/Oncology

HOSPITAL COMMITTEES

2002- 2005 Transfusion Committee Rhode Island Hospital/Hasbro Children’s Hospital

April 2008 - current Cofounder and Director of Sickle Cell Task Force, RIH Rhode Island Hospital/Hasbro Children’s Hospital

April 2008 – current Establishment Hematology/Oncology Transition to Adult Clinic Rhode Island Hospital/Hasbro Children’s Hospital

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April 2013 current Zero Harm Venothromboembolous Committee Team leader

10/2013 – current Cancer Oversight Committee Pediatric Representative

Sept 2014-2015 Search Committee Chair Faculty search for Pediatric

MEMBERSHIP IN SOCIETIES

1998-present American Society of Hematology

2001-present Children’s Oncology Group

2002-present American Society of Clinical Oncology

2002-present American Society of Pediatric Hematology/Oncology (Reviewer for Journal of Pediatric Hematology/Oncology)

2002-2007 American Association of Blood Banking

2002-present Pediatric Sickle Cell Consortium Section Leader, Subcommittee for Transfusions Section Leader, Subcommittee for Avascular Necrosis Chair of Research Committee

1996 – present American Academy of Pediatrics, FAAP, since 2008

2008 – present Sickle Cell Awareness Association of Rhode Island Cofounder and Board Member

2012 – present North American Pediatric Aplastic Anemia Consortium Cofounder and Board Member

2014 – present Tomorrow Fund Board Member, Medical Advisor

2014 – present New England Blood Club Founding Member, Presenter Bimonthly Regional Webinar discussing difficult cases.

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PUBLICATIONS Manuscripts:

Chawla A, Chou SH, Lee TH, Busch MP, Cowan MJ. Increased engraftment following in utero transplantation of MHC-mismatched bone marrow cells and CD 86-dendritic cells in a fetal mouse model. Transplantation, 2001: 72 (11): 1768-76.

Bhattacharyya S, Chawla A, Smith K, Zhou Y, Sohel T, Cowan MJ. Increased engraftment with minimal graft-vs-host-disease following in utero transplantation of S-59 psoralen/UVA light-treated sensitized T cells and adult T cell depleted bone marrow in fetal mice. Journal of , 2002: 169 (11): 6133-40.

Young C, Losikoff P, Chawla A, Glasser L, Forman E. Transfusion Acquired Trypanosome cruzi infection. Transfusion 2007;47:540-544

Young C, Chawla A, Berardi V, Padbury J, Skowron G, Krause P and Babesia Testing Investigational Containment Study Group. Preventing transfusion-transmitted babesiosis: preliminaryexperience of the first laboratory-based blood donor screening program. Transfusion 2012; 52;1523- 1529

Chawla A, Sprinz P, Welch J, Heeney M, Usmani GN, Pashankar F, Kavanagh P. Weight Status of Children with Sickle Cell Disease: Has the Obesity Epidemic Arrived? Pediatrics 2013 Volume 131 issue 4, Page 1168

Abstracts:

Chawla, A, Chou SH, Smith K, Cowan MJ. Role of T-lymphocytes in murine in utero bone marrow stem cell transplantation. American Society of Hematology meeting, San Francisco (poster). December, 2000.

Philippa Sprinz M.D., Anjulika Chawla M.D., Karla Fuentes M.D., Matthew Heeney M.D., Mary Huang M.D., Michael Isakoff M.D., Betty Leef RN, Suzette Oyeku M.D., MPH, Farzana Pashankar M.D., Maria Pelidis M.D., Anne Rossi M.D., Kathleen Ryan RN, MPH, Naheed Usmani M.D.: The New England Pediatric Sickle Cell Consortium. 'Adolescents with Sickle Cell Disease: Clinical Data from the New England Pediatric Sickle Cell Consortium'. Poster Presentation at the 29th Annual Meeting of the National Sickle Cell Disease Program, Memphis Tenn. April 8-12th 2006

Philippa Sprinz M.D., Anjulika Chawla M.D., Karla Fuentes M.D., Matthew Heeney M.D., Mary Huang M.D., Michael Isakoff M.D., Betty Leef RN, Suzette Oyeku M.D., MPH, Farzana Pashankar M.D., Maria Pelidis M.D., Anne Rossi M.D., Kathleen Ryan RN, MPH, Naheed Usmani M.D.: The New England Pediatric Sickle Cell Consortium. 'Adolescents with Sickle Cell Disease: Psychosocial Data from the New England Pediatric Sickle Cell

6 Consortium' Poster Presentation. 29th Annual Meeting of the National Sickle Cell Disease Program, Memphis Tenn. 2006

A.Paroskie MD, A. Chawla MD, N. Hagstrom MD, M. Heeney MD, M. Huang MD, J. Luty MD, F. Pashankar MD, M. Pelidis MD, A. Rossi MD, N. Usmani MD, K. Murphy MT SBB, P. Sprinz MD, “Red Blood Cell Transfusion Practices within the Institutions of the New England Pediatric Sickle Cell Consortium. Oral Presentation at the 36th. Annual Convention of the Sickle Cell Disease Association, New Orleans, September 2008.

Halpern, A; Welch, JG, Chawla, A; Prevalence and Impact of Obesity in Sickle Cell Disease, American Society in Hematology San Francisco, December, 2008

Chawla, A, Capuano, S, Lake, S, Spirito, M, Bowering, N; Max All Stars Palliative Care Program: Multiagency Approach to Palliative Care. Palliative Care Conference at MD, October, 2008

Wiliams D, Coates T, Shimamura A et al Chawla, A; Diagnosis and Treatment of Pediatric Acquired Aplastic Anemia: An Initial Survey the North American Pediatric Aplastic Anemia Consortium (NAPAAC), Poster presentation; ASPHO Annual Meeting April 2013

Chawla, A, Sprinz.P, Kavanagh, P: Pediatric Prescriber Practices of Hydroxyurea in Sickle Cell Disease; accepted to ASPHO 2016 Annual Meeting, Minneapolis, Minnesota

Other Media Publications

New England Pediatric Sickle Cell Consortium. Clinical Protocol Guidelines:

K. Ryan, A. Chawla, S. Space, M, Heeney; Prevention and Treatment of Stroke in Pediatric Patients, November 2003 (www.nepscc.org)

K. Ryan, A. Chawla, M. Heeney Blood Transfusion for Pediatric Patients with Sickle Cell Disease December 2003 (www.nepscc.org)

K. Ryan, P. Sprinz, A. Chawla, M. Heeney, Routine Health Care Maintenance of Pediatric Patients with Sickle Cell Disease, May 2004 (www.nepscc.org)

K.Ryan, A. Chawla, M Heeney Management of Acute Chest Syndrome in Sickle Cell Disease January 2005 (www.nepscc.org)

INVITED PRESENTATIONS:

1. Sickle Cell Disease: Management in the year 2000 Grand Rounds, Kaiser Vallejo, CA. April, 2000.

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2. Annual invited lecturer and founder for Pawtuxet Valley Nursing Conference 2003- 2006, CEU awarded • CBC interpretation 04/17/02 • Fever and Neutropenia 10/02/02 and 08/06/03 • Sickle Cell Disease in Pediatrics: Controlling the Crises 04/20/04 • Chemotherapy: Short and Long Term Side Effects 05/12/06 • Adolescent Hematology/Oncology 12/03/07

3. Invited Lecturer for Hole in the Wall Gang Specialty Conference for providers Annually in July of each year 2002-2009 Hole in the Wall Gang Camp, Ashford, CT

4. Management of Sickle Cell Disease, Medical Hematology/Oncology Grand Rounds RIH October 24th, 2005.

5. Erythrocytapheresis in the treatment of sickle cell disease Rhode Island Blood Banking Society Meeting Providence RI October 13, 2005.

6. “Things that go lump in the night….or yes, that is a tumor.” Emergency Medicine Grand Rounds RIH November 15, 2006.

7. Hospital Based Palliative Care Conference for Hospitalists RIH February 14, 2007.

8. Loss and Transitions in Children with Special Health Care Needs RIPIN Annual Meeting, Providence, RI April 27, 2008.

9. Patient Care Management in Sickle Cell Disease Improving Health and Social Well-being, CSQCC meeting, New Britain, CT May 3rd 2008.

10. Transfusions in Sickle Cell Disease 60th Annual Clinical Lab Science Convention Rhode Island Convention Center

8 Providence, RI May 6th, 2008.

11. Stillborn with prenatal overgrowth syndrome Clinical Conference Women and Infants Hospital Sept 17th 2008

12. Erythrocytapheresis in sickle cell disease 62nd Annual Clinical Lab Science Convention Rhode Island Convention Center Providence, RI May 5th, 2010

13. Newborn with hematoma on hand Clinical Pathology Conference Women and Infants Hospital March 17th, 2011

14. Neonatal Brain Tumors Perinatal Management Conference Women and Infants Hospital August 8 2012

15. Challenges of Pediatric Survivors Survivor Celebration Roger Williams Park, Rhode Island Sept 23rd, 2013

16. Tracking Nonclinical Faculty Activity at Brown ASPHO Annual Meeting May 14, 2014

17. Walking the Line Bioethics of Cure versus Comfort Care at the End of Life RIH September 8, 2015

18. Perinatal Neuroblastoma MADAM Conference December 18, 2015

19. Mandibular Mass in an Infant CPC Women and Infants Hospital January 4, 2017

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HOSPITAL TEACHING CONFERENCES

1. Sickle Cell Trait: Disease or Discrimination? Pediatric Grand Rounds: Hasbro Children’s Hospital, Providence RI February 2011

2. Pediatric Surgery Grand Rounds: Splenectomy in hematologic disorders Dec 1, 2010

3. Ferrilocks and the Three Bears: The New Story of Iron Grand Rounds, Hasbro Children’s Hospital, Providence RI, November 2008

4. Perinatal management conference: Anemia and Parvovirus, May 11, 2005

5. Neonatal Medicine Fellows Lecture: Newborn Screening and Hemoglobinopathies, May 12, 2005

6. Sickle Cell Disease: Management in the era of hydroxyurea: Grand Rounds, Hasbro Children’s Hospital, Providence, RI. February 2002.

7. Newborn Screening of Hemoglobinopathies Grand Rounds, Hasbro Children’s Hospital, Providence, RI. February 27, 2004.

8. Pediatric Hematology/Oncology Fellows Didactic Curriculum 2002 - current– Developed Initial Didactic curriculum, including research colloquium and journal club, currently present 20% of weekly lectures • Megaloblastic anemias • Bone marrow failure syndromes • Thrombocytopenia • Beta thalassemia • The erythron • Platelets • Congenital neutrophil disorders • Granulocyte adhesion and migration • Hemoglobin overview • Humoral immunodeficiencies • Innate immunity • Perinatal neuroblastoma • Sickle Cell complications • Iron metabolism • Splenic function • Bleeding disorders cases

10 • Multiple board review question sessions: Transfusion, transplant, bleeding diathesis, brain tumors, cancer , thrombosis

9. Resident Noon Conferences – been responsible for coordinating faculty to present since 07/05, as well as presenting 3-4 conference per year since 01/02: • Infection in the Immunocompromised host 07/18/02, 08/06/03 • Cancer Epidemiology 06/09/03, 05/01/06 • Transfusion Therapy, 09/08/03, 03/06,12/1/10 • Side effects of chemotherapy 02/26/04 • Late effects of chemotherapy, 02/23/04 • End of life care, 06/02/09, 9/15/09,12/3/10 • Neuroblastoma, • Presentation of solid tumors, 5/15/05 • Bleeding diathesis, • Innate immunity, • Sickle Cell Disease 4/24/08, 11/18/08, 06/17/09 • Pain Management 04/24/09 • Hemolytic Anemia 12/05, 05/19/09

10. Hemoglobinopathies; noon conference for Internal Medicine Dec 3rd, 2009 and Dec 17th, 2009, December 13, 2010

OTHER MENTEES

Students 1. Sarah Whittle, Tufts Undergraduate Student Use of steroids in Sickle Cell Disease Undergraduate Summer Research Project 2004

2. Aisha Abdulkadiri – High School Student Effect of cancer therapy on patients and families Mentoring for senior project. 10/09 – 2/2012

RESEARCH

1. Senior research project involving DNA-membrane interactions of B.subtilis Mentor: William Firshein, Ph.D Wesleyan University, Middletown, CT 1988-1989

2. Research technician in Robert Gallo’s laboratory projects involving HIV1 gp41 mutations and the effect of multimerized tar elements on HIV1 transactivation Mentor: Marvin Reitz, Ph.D.

11 Laboratory of Tumor , NCI, Bethesda, MD 1989-1991

3. Post-doctoral project researching the mechanisms of tolerance in murine in utero bone marrow transplantation, especially related to T-cells. Mentor: Morton Cowan University of California, San Francisco 1999-2001

4. “Admission Practices and Access for Care for Sickle Cell Disease in the Adolescent Young Adult Population” Hasbro Children’s Hospital: October 2009

5. “Prevalence of Obesity in Sickle Cell Disease” Hasbro Children’s Hospital PI: Chawla, A. Department of Pediatrics: $7700 2007 – current

6. AVN in Children with Sickle Cell Disease and Acute Leukemia, Screening MRI and Risk Factors PI: Chawla, A, mentor for Jennifer Welch Cure Kids Radiothon: $25,000 Hasbro Children’s Hospital 2006 – 2010

7. Erythrocytapheresis in Hemoglobinopathies Using Double Lumen ports, PI: Chawla, A. Funding: Department of Pediatrics $6000 Hasbro Children’s Hospital 2006 – 2008

8. MRI perfusion in Children with Sickle Cell Disease Co- PI: Chawla A and Cassesse J. Funding : Department of Radiology $10,000 Hasbro Children’s Hospital 2006- 2010

9. Neurocognitive Function in Children with Sickle Cell Disease Collaboration with Christine Trask, MD., Neuropsychiatry Hasbro Children’s Hospital 2007-Current

10. Daiichi Sankyo DU176b-A-U157 Phase I trial of Edoxaban.

12 PI: Chawla, Anjulika Funding Daiichi Sankyo $47,500

11. Daiichi Sankyo

12. Eltrombopoag study through NAPAAC

13. COG member: 62 protocols open in institution.

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