Anti-VAMP1 Monoclonal Antibody, Clone TQ22 (DCABH-2273) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-VAMP1 monoclonal antibody, clone TQ22 (DCABH-2273) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to Synaptobrevin

Antigen Description Synaptobrevins are highly conserved between vertebrates and invertebrates. It is a major constituent of synaptic vesicles and peptidergic secretory granules in all neurons examined so far. In addition, it is present on secretory granules of neuroendocrine cells. Synaptobrevins, Syntaxins, and the 25 kDa synaptosomal associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.

Specificity This antibody reacts with native, denatured and recombinant synaptic vesicle protein Synaptobrevin (aa 1-118).

Immunogen The details of the immunogen for this antibody are not available.

Isotype IgG1

Source/Host Mouse

Species Reactivity Cat, Human, Pig

Clone TQ22

Purity Protein G purified

Conjugate Unconjugated

Applications WB, ELISA, ICC/IF

Positive Control Native, denatured and recombinant Synaptobrevin protein.

Format Liquid

Size 100 μl

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) [ Homo sapiens ]

Official Symbol VAMP1

Synonyms VAMP1; vesicle-associated membrane protein 1 (synaptobrevin 1); SYB1; vesicle-associated membrane protein 1; VAMP 1; synaptobrevin 1; synaptobrevin-1; VAMP-1; DKFZp686H12131;

Entrez Gene ID 6843

Protein Refseq NP_055046

UniProt ID F5GZV7

Chromosome Location 12p

Pathway BoNT Light Chain Types B, D, and F cleave VAMP/Synaptobrevin, organism-specific biosystem; Botulinum neurotoxicity, organism-specific biosystem; Disease, organism-specific biosystem; Neuronal System, organism-specific biosystem; Proteolytic cleavage of SNARE complex proteins, organism-specific biosystem; SNARE interactions in vesicular transport, organism- specific biosystem; SNARE interactions in vesicular transport, conserved biosystem;

Function protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]