GMP LIST OF CONTENTS: Infusion therapy Antiseptics Rheosorbilact 8 Decasan 16 Latren 8 Horosten 16 Soda Buffer 9 Xilat 9 Tivortin 10 Tivortin Aspartate 10 Antibiotics GiK 11 Hekodez 11 Leflocin 17 Sorbilakt 12 Leflocin 750 17 Aminocaproic acid, sol. 5% 12 Bigaflon 18 Ofloxacin 18 MAXICIN 19 ПРОСТЫЕ ИНФУЗИОННЫЕ РАСТВОРЫ Soluseptol 19 Ornigil 20 Sodium chloride sol. 0,9% 13 Ciprofloxacin 20 Glucose. 5% 13 Water for injection 13 Ringer's solution 14 Ringer-laktat solutio 14 Drugs modifying a cartilage Sodium hydrocarbonate sol. 4% 14 Manit, 15% 15 Polyglucinum 15 Hyalual-arthro 21 Rheopolyglyucinum 15

2 Solutions for drinking Clinical Nutrition Irrigation solutions

Laktuvit 22 Aminol 27 Tivortin Aspartate 23 GluXyl 27 Turusol 30 DECASAN - CYTOCLIN 30 CYTOCLIN 31 Anti-TB drugs

Isoniazid syrup 24 ANTIVIRAL RIFONAT 24 PREPARATIONS ACCESSORIES FOR INFUSION Inbutol 25 THERAPY Paskonat 25 AKK 28 SOLUVEN 32 Syringes of Yuria- Pharm with two needles 33 Anti-protozoal drugS Systems for infusions of Yuria Antifungal drugs Pharm (PS and PB) 33 Metronidazole 26

Fluconazole 29 FOR NOTES Fluconazole 400 мг 29 34 - 35 Anesthetic

NOVOCAINE, sol. 0,25% 26

3 «YURiA-PHARM» - dynamically Pacific, African and South America markets, therefore in some growing company countries we have already started the registration process for the preparations planned to be distributed. Pharmaceutical company YURiA-PHARM was found in 1998. Today YURiA-PHARM is the leader manufacturer of YURiA-PHARM total headcount is constantly growing and solutions for infusion not only in Ukraine but also in CIS. We at the moment exceeds 800, 2/3 of them being involved in supply medical facilities with more than 100 items of blood- production and R&D. and plasma substitute solutions, original infusion drugs, antibiotics, fungicidal drugs, syrups, antiseptics, parenteral «YURiA-PHARM» – a wide range of popular feeding preparations, anti-tuberculosis drugs, syringes, I.V. sets. original and generic infusion preparations The assortment of products fully covers the requirements of Our company produces a number of preparations (original stationary curative establishments in infusion therapy. Our and generic), which are not produces in CIS countries - product line sums up to more than 40 preparations. Annual Reosorbilact®, Sorbilact®, Decasan®, Horosten® etc. For turnover of the company exceeds 60 mln bottles per year. instance, Reosorbilact® (30% of total distribution of the «YURiA-PHARM» confidently takes in the preparations included in B 05 ATC code (B05 - Blood leading position in the export markets substitutes and perfusion solutions) and Sorbilact® constitute a basis of infusion therapy in Ukraine. They have completely We deliver our products to Russia, Moldova, Kazakhstan, replaced polyvinylpyrrolidone preparations (such as Hemodez, Uzbekistan, Azerbaijan, Tajikistan, Kirgizia, Turkmenistan and Neohemodez etc.) prohibited in many European and other Georgia. More than 100 items are now being registered for countries, and restricted dextran preparations (Reopolyglucin). usage in different countries and the number is continuously growing. In our portfolio we also have unique cosmetological treatments - Hyalual® (an anti-age therapy, preparation for In 2008 YURiA-PHARM Corporation has received a Certificate realization of procedure of redermalization - rejuvenations of compliance to international quality management standards by renewal), injectional preparations modifying a cartilage ISO 9001 (9001:2009). In 2011 YURiA-PHARM Corporation has - Hyalual®-Artro - unique innovative cartilage protective complited WHO-GMP certification. Now we plan to enter Asia- preparation of new generation. It is an effective combination

4 of hyaluronic acid and sodium succinate, which already accessibility of treatment, we improve the presentations and has showed the efficiency in treatment of patients with dosages of the preparations on a permanent basis. osteoarthrosis. At the moment our products are released in 9 forms, including prefilled syringes, nebules, bags for irrigation solutions, «YURiA-PHARM» - appreciated by the polypropylene bags, PVC bags, glass bottles, plastic bottles, physitians and the scientific medical tablets. community «YURiA-PHARM» - a right hand of any We cooperate intensively with many research institutions in physician the field. For the first time in CIS, in collaboration with Blood Pathology and Transfusion Medicine Institute of Ukraine's Our preparations accelerate the patients' recovery due to their Academy of Medical Science, we have developed a group of higher efficiency, considerable decrease of complications and complex multifunctional infusion solutions - Reosorbilact®, minimization of side-effects. Numerous reputable medical Sorbilact®, Xylat®, which today make basis of new direction investigations prove a visible time saving in stationary in the clinic of internal medicine - "Low-volume infusion treatment and higher therapy comfort level. These factors therapy". Corporation conduct an intensive research of the allow reducing the treatment cost and increasing an average new preparations and also examine more deeply the capacity annual bed turnover. of the existing ones. We make large investments in Research & Development and prove the quality and efficiency of our preparations according to the requirements of the “case-based «YURiA-PHARM» - a reliable and medicine”. advantageous partner «YURiA-PHARM» - constant improvement According to YURiA-PHARM long experience, practical usage of production according to market of its preparations enhances an overall image both of a requirements medical facility and of the physician. Keeping in mind constant enhancing of quality and

5 Uncompromising quality and reasonable pricing have made our preparations bestsellers in Ukraine and CIS and we have every reason to expect similar success in other countries.

«YURiA-PHARM» - some short facts:

• leader in production of solutions for infusion; • annually growth rate more than 40%; • more than 100 items in the product line; • total headcount more than 800; • annual turnover up to 60 million units; • exports to 9 countries; • 80% of annual net profit is invested in modernization of production; • each year about 10 new medical preparations are delivered; • system quality control ISO 9001 : 2009 operates; • a production works in accordance with GMP standards.

6 “Yuria-Pharm” Corporate Philosophy

OUR DESIGNATION Life is the main global value! OUR VISION Our main target is to protect and improve it! “Yuria-Pharm” is a leading innovational pharmaceutical corpo- ration in Ukraine, the best employer in industry. OUR MISSION - We create unique medications for human treatment and OUR VALUES recovery. 1. Our clients and partners who trust us. - Through our patented technologies, we bring innovations in 2. We are ambitious professional team united with common infusion therapy and set the style in pharmaceutical business. corporate spirit. - We achieve recognition of the Society, Physicians and 3. The best quality of: Patients. - our products; - We apply creative power of our Employees and Partners and promote their welfare. - relationships with our Сlients; - internal communications based on high ethical standards. 4. Maximum outcome and high business profitability. 5. Self-realization of every Employee.

7 INFUSION THERAPY

REOSORBILACT® LATREN®

Number One Enhanced infusion therapy drug microcirculatory effect Ukraine’s research heritage

2009

How supplied: How supplied: 200 ml and 400 ml vials. 100 ml and 200ml vials.

REOSORBILACT is a polyfunctional balance correction, mild metabolic acidosis LATREN is an infusion solution with a balanced hyperosmolar drug. The rational combination correction, hepatoprotective action. isoosmolar electrolyte solution (Ringer's lactate of components that complement and REOSORBILACT is the foundation of smallscale solution) which potentiates the effect of potentiate each other allows achieving infusion therapy, a modern branch of internal pentoxifylline. Effective for both peripheral and a polyfunctional effect: hemodynamics medicine. brain circulation disorders. stabilization, pronounced detoxication LATREN is supplied as a final dosage form, therefore effect, improved microcirculation and blood eliminating the risk of technical error or solution rheological properties, hydro-electrolytic infection.

8 INFUSION THERAPY

SODA-BUFFER® XYLAT®

Buffered Infusion therapy sodium for diabetes hydrocarbonate mellitus and solution ketosis of different genesis

How supplied: How supplied: facilitates secretion of endogenic 100 ml, 200 ml and 20 ml vials. 200 ml and 400 ml vials. insulin. Of all carbohydrates and polyalcohols, xylytol has the most pronounced antiketogenic action. The use of Soda-Buffer is is physiological for the human body. A multicomponent hyperosmolar Sodium acetate is a slow-acting recommended for diseases This ensures exceptional safety of this solution containing xylytol, sodium alkalizing agent that ensures acidosis and pathological conditions drug. acetate and a balanced electrolyte correction without sharp pH level accompanied with metabolic complex. Has antiketogenic, fluctuations. Due to the balanced The use of Soda-Buffer of 20 ml is electrolyte complex, the drug acidosis. Unlike regular baking soda recomended for correction of pH nitrogenpreserving and lipotropic (4.2% sodium carbonate) with a action. Xylytol is a pentabasic ensures correction of electrolyte of acid infusion solutions, makes imbalances. Xylat is an effective pH of 8.3-11.0, Soda-Buffer, due to an angioprotective effect and also alcohol with insulinindependent a patented CO2 solution buffering utilization that does not influence solution for cases of sugar diabetes minimize a bad senses of patient and ketosis of different genesis. technology, has a pH of 7.3-7.8, which during protracted infusion therapy. the blood glucose level and

9 INFUSION THERAPY

TIVORTIN® TIVORTIN® ASPARTATE

Indispensible nitric oxide Indispensible donor nitric oxide donor

How supplied: How supplied: 4.2% infusion solution in 100 ml vials. oral solution in 100 ml and 200 ml vials.

The active ingredient of Tivortin • decreases leukocyte activation and Tivortin Asparate oral solution is part Tivortin Aspartate contains is the L-arginine aminoacid, the adhesion to endothelium; of a switch therapy with NO donors the L-arginine aminoacid, an only substrate used for nitric oxide • i n h i b i t s t h r o m b o c y t e a d h e s i o n , and ensures: indispensible NO donor, and aspartic (NO) synthesis in the human activation and aggregation; • maintained high clinic effectiveness acid. Can be used for patients with body. Tivortin is a physiological • inhibits adhesion protein synthesis; of the therapy; concurrent diabetes mellitus. vasodilatator and vascular tone • prevents pathologic vascular wall regulator. Tivortin is a physiological remodeling and atherosclerosis • shorter in-patient treatment time; angioprotector: progression. • possibility to continue treatment at home.

10 INFUSION THERAPY

GIK® GEKODEZ®

Ready form Economy antishock of polarizing therapy solution

How supplied: How supplied: 100 ml and 200 ml vials. 200 and 400 ml vials; 500 ml polymer containers.

GIK provides the transport of has antiarrhythmic action, lowers 6% HES solution 200/0.5; volemic Gekodes is a cost-efficient glucose in cardiomiocites, stimulates the heightens sensitivity to cardiac effect of 85-100%. antishock therapy (the most a synthesis of ATP, regulates a glycosides and decreases their Gekodes is a plasma substitute with affordable HES solution in Ukraine) transmembrane transport of ions of cardiotoxic effect. pronounced volemic effect, high K, Na, Ca. GIK is supplied as a final dosage acceptability and additional specific GIK normalizes metabolism of form, therefore eliminating the risk of advantages (lowers the «capillary myocardium in the conditions of technical error or solution infection. loss» rate). ischemia: provides a heart glucose and reduces oxidization of fat acids,

11 INFUSION THERAPY

AMINOCAPRONIC ACID, SORBILACT® 5% solution

Hyperosmolar complex Haemostatic infusion solution preparation

- stimulation of laxation - treatment of intracraneal hypertension

How supplied: How supplied: 200 ml and 400 ml vials. 100 ml vials;

Sorbilact - a prophylaxis and treatment of Sorbilact's additional osmodiuretic action provides enteroplegias are in an early postoperative period. maximal effect at therapy of cerebral edema. The Sorbilact stimulates intestinal peristaltic mildly and presence of the balanced electrolyte composition efficiently; it can be applied starting from the 1-2nd diminishes the losses of electrolytes and does not day after surgery. The intestinal motility stimulation create a "rebound" effect. mechanism is based on the direct influence of Sorbilact - effective haemodynamic preparation the drug on the neuroreceptor apparatus of the which quickly removes hypovolemia and increases intestines, increase of mesenterial circulation and stimulation of villikinine and cholecystokinine SAP and CPP. synthesis.

12 SIMPLEX INFUSION SOLUTIONS

WATER FOR GLUCOSE 5% POTASSIUM SODIUM CHLORIDE 0,9% solution INJECTIONS solution CHLORIDE

Concentrate for solution for infusion 7,5%

How supplied: How supplied: How supplied: How supplied: 100, 200 and 400 ml vials; 100, 200 and 400 ml vials; 200 ml and 400 ml vials. 10 ml and 20 ml vials. containers of polymer 100, 200, 250, 500, 1000, 2000, 100, 200, 250, 500, 1000, 2000, 3000, 5000 ml. 3000, 5000 ml polymer containers

13 SIMPLEX INFUSION SOLUTIONS

RINGER'S LACTATE SODIUM HYDROCARBONATE RINGER'S SOLUTION SOLUTION 4% solution

How supplied: How supplied: How supplied: 200 ml and 400 ml vials; 200 ml and 400 ml vials; 100 ml and 200 ml vials. 250 ml and 500 ml containers. containers 100, 200, 500 and 1000 ml.

14 SIMPLEX INFUSION SOLUTIONS

MANNITOL, POLYGLUKIN solution RHEOPOLYGLUKIN 15% solution solution

How supplied: How supplied: How supplied: 200 ml and 400 ml vials. 200 ml and 400 ml vials. 200 ml and 400 ml vials.

15 ANTISEPTICS

DEKASAN® HOROSTEN®

The most effective Protect yourself! antiseptic solution

How supplied: How supplied: 100 ml, 200 ml, 400 ml vials; 1000 ml polybags, 2 ml and 4 ml containers. 400 ml vials, 30 ml and 100 ml spray.

Dekasan — antiseptic, decametoxyn it a good choice for treatment of Active component — decametoxyn, skin, but ensures quick drying of the solution for external and endocavitary bacterial and fungal skin diseases, a widely known highly effective solution. application. 1 ml of solution contains microbial eczema, pyoinflammatory antiseptic. A wide range of antibacterial, antiviral, 0.2 mg of decametoxyn. One of soft tissue involvement, dental diseases, Auxiliary components: antifungal and antiprotozoal effect. the most important advantages of inflammatory respiratory diseases, The absence of an allergenic effect is Dekasan is the fact that it affects treatment of wounds, peritoneal • Glycerin – softens and moisturizes ensured by the desensitizing effect of only bacterial cells, and not the cells commissures prevention, efficient the skin. decametoxyn. of the human body. Additionally, it prophylaxis and treatment of bedsores • Citral — stimulates a tissues has anti-inflammatory, desensitizing and trophic ulcers. Dekasan is also highly reparation and gives a lemon aroma. and spasmolitic effect, which makes effective for inhalation treatment. • 15% alcohol — does not dry out the 16 ANTIBIOTICS

LEFLOCIN® LEFLOCIN® 750

The gold standard of empiric The shortest antibiotic therapy. path to the The safety standard of goal! fluoroquinolones.

How supplied: How supplied: 500 mg/100 ml vial, 500 mg tablets, 10 tablets in a blister. 750 mg/150 ml vials.

Antibacterial drug of the III generation of Unique mechanism of action provides Short high-dosage treatment by levofloxacyn (750 mg once fluoroquinolones. the expressed bactericidal effect and daily, during 5 days) is officially approved for patients over 18 The clinical and economic advantages minimum risk of resistance development. years of age with community-acquired pneumonia, acute of levofloxacyn over other groups of Levofloxacin is confessed by one of the bacterial sinusitis, as well as aggravated urinary infections and antibacterial drugs has been scientifically most safe antibacterial preparations of acute pyelonephritis. attested in treatment of infections of accessible today. 750 mg of levofloxacin in one vial ensures the best treatment different etiology and localization. effects in record time.

17 ANTIBIOTICS

BIGAFLON® OFLOXACIN

The right kind of gatifloxacin

How supplied: How supplied: 400mg/100ml and 800mg/200ml vials, 400 mg tablets, 10 tablets in blister. 200 mg/100 ml and 400 mg/200 ml vials.

Gatifloxacin is a IV generation fluroquinolone. Bigaflon's effectiveness and safety are tested Quick and reliable antibacterial therapy for a wide Its wide range of effect, including gram- by many years of clinical application and the range of infections negative, gram-positive, atypical and anaerobic reputation of its manufacturer — YURiA-PHARM, microgerms, ensures highly effective treatment the leader of the Ukrainian market of infusion of virulent diseases regardless of their etiology. drugs.

18 ANTIBIOTICS

MAXICIN® SOLUSEPTOL®

Co-trimoxazole More powerfull! syrup as effective as an intravenous drug!

How supplied: Concentrate 400 mg/20 ml for solution for infusion preparing in dark glass vials with How supplied: a solvent in a complete set syrup, 4 ml of which contains: 100 mg of sulpamethoxazole and 20 mg of trimethoprim; in 100 ml and 200 ml bottles.

SOLUSEPTOL ensures consistent peak plasma concentration levels that MAXICIN® (moxifloxacin) - is the newest A presence in the complete set of solvent approximate those achieved by the intravenous solution, and has an fluoroquinolone of IV generation. with the SOLUVEN system provides an elimination half-life of a tablet drug. exceptional quickness, comfort and safety Uniting in itself all positive internalss of Co-trimoxazole is the drug of choice for treatment and prevention of preparation of solution. previous fluoroquinolones, MAXICIN® of urinary infections, HIV/AIDS-associated infections (pneumocystic possesses the wide spectrum of pneumonia, toxoplasmosis) and infectious diarrheas. Co-trimoxazole is bactericidal action, good bearableness, included into the British National Formulary and the WHO Formulary. minimum risk of selection of resistance. SOLUSEPTOL is a highly effective and pharmacoeconomically favorable The dark glass vials protect preparation alternative to linezolid, clindamycin and vancomycin for treatment from influence of ultraviolet rays. of infections caused by methicillin-resistant Staphilococcus aureus (MRSA). 19 ANTIBIOTICS

ORNIGIL® CIPROFLOXACIN

Not a metronidazole!

How supplied: How supplied: 500 mg/100 ml and 1000 mg/200 ml vials; 500 mg tablets, 10 tablets in a blister. 200 mg/200 ml vials, 200 mg/100 ml; 400 mg/200 ml containers.

- No cross-resistance with metronidazol. posed to preparation for a perioperative Highly effective antibacterial drug for treatment of infectious - Side effect occurrence rate does not prophylaxis and treatment of surgical diseases of various origin. exceed 3.7%. infections; - Effectiveness for treatment of - Long half-life period provides high trichomoniasis and prostatitis is 98.5%. effectivenes of therapy in administration regimen 1000 mg once daily or 500 mg - Powerfull bactericidal action against twice daily. wide spectrum of anaerobes; - Most corresponds to the requirements

20 DRUGS MODIFYING A CARTILAGE

HYALUAL®-ARTRO

Move without pain! A unique decision for patients with osteoarthrosis

How supplied: 1.1% and 1.8% in pre-filled 1 ml and 2 ml syringes, with additionally supplied needles for intraarticular injection.

Hyalual-Artro is a preparation for functional state of joints and quality of life All these effects of sodium succinate allow intraarticular injection, which has the of patient. to increase life-span of cartilage tissue and opportunity to influence on pathogenetic actively fights for the postponement of mechanisms of progressing of The second component of a preparation endoprotesis setting. osteoarthrosis. - Sodium succinate has a pathogenetic effects. It normalizes the intracellular The first component of a preparation - metabolism of the hondrocytes, stimulates a Hyaluronic acid has an anaesthetic and syntesis of intracellular matrix of a cartilage, antiinflammatory actions and improves the has an antioxidative action.

21 SOLUTIONS FOR DRINKING

LACTUVIT®

A natural laxative that normalizes the intestinal function

Lactuvit is a physiology and safe In case of hepatic encephalopathia regulator of a bowel motor function. Lactuvit decreases concentration It ensures bowel evacuation and of ammonia in the blood due to softens a bowels content. It results diminishing of its receipt from to the correction of chronic lock bowels. Lactuvite decreases bowels practically of any its form. Thus does pH, hinders to reproduction of not render meaningful side effects bacteria and suction of ammonia and does not cause getting used. and other toxins. The acting mechanism of Lactuvit is similar to that of food fiber. It creates an ideal nutritive medium for beneficial bifidus bacteria and lactic acid bacilli. It assists renewal of normal balance of microflora.

How supplied: 100 ml and 200 ml vials.

22 SOLUTIONS FOR DRINKING

TIVORTIN® Aspartate

Indispensible nitric oxide donor

The active ingredient of Tivortin atherosclerosis occurrence and Aspartate is the Larginine aminoacid, progression. The pharmaceutical the only substrate used for nitrogen form – oral solution – ensures oxide (NO) synthesis in the human dosage accuracy and convenient body. administration. Tivortin Aspartate can Tivortin is a physiological vasodilatator, be used for patients with concurrent a vascular tone regulator in normal diabetes mellitus. conditions and as response to various Tivortin Asparate oral solution is part stimuli. of a switch therapy with NO donors Tivortin is a physiological and ensures: angioprotector: • maintained high clinic effectiveness • decreases leukocyte activation and of the therapy; adhesion to endothelium; • shorter in-patient treatment time; •i nhibits thrombocyte aggregation • possibility to continue treatment at and parietal thrombosis; home. • inhibits vessel smooth muscle proliferation and pathologic vascular wall remodeling. All of the above contributes to normalization of the endothelium How supplied: function and prevention of oral solution in 100 ml and 200 ml vials.

23 ANTI-TUBERCULOSIS DRUGS

ISONIAZID syrup RIFONAT®

Protect your The most effective child from pharmaceutical form tuberculosis! of the most effective drug!

How supplied: How supplied: 100 ml and 200 ml vials. Infusion solution concentrate 30 mg/ml. 5, 15 and 20 ml vials (150, 450 and 600 mg of Rifamycin accordingly). 15 ml and 20 ml vials (450 and 600 mg of Rifamycin accord- ingly) complete with a solvent. The pharmaceutical form – a syrup The accurate dosing of syrup – is used for the most effective ensures treatment and prophylaxis Intravenous form of Rifamycin. In this way the highest efficiency and safe treatment and chemical effectiveness and prevents side First-line antituberculosis drug. of treatment is ensured along prophylaxis of tuberculosis for effects. Intravenous administration with minimizing the risk of diseased and infected children with 1 ml of Isoniazid syrup contains 20 of RIFONAT provides 100% development of MTB resistance. BCG vaccination complications, as mg of isoniazid. bioavailability and creates Inhalation application is possible. well as for those who had come in maximum concentrations of contact with tuberculosis patients. preparation in blood and tissues.

24 ANTI-TUBERCULOSIS DRUGS

INBUTOL® PASKONAT®

Time-tested Control and tuberculosis effectiveness! treatment

How supplied: How supplied: 10% solution in 10 ml and 20 ml vials. 12 g/400 ml vial.

Intravenous form of Ethambutol. while maintaining high treatment PASKONAT is used mainly for tuberculosis treatment allows First-line antituberculosis drug. effectiveness. Decreasing the treatment of tuberculosis form enhancing the effect of other Resistance of bacillus Kochii to ethambutol dosage lowers the risk that had not responded to earlier antituberculosis drugs and slow Inbutol develops slowly. The of tuberculosis polychemotherapy therapy, recurrent diseases, forms down the development of the use of Inbutol (bioavailability of side effects. resistant to the main antituberculosis bacillus Kochii resistance to the 100%) instead of a tablet form of drugs, and in cases of patient drugs. ethambutol (bioavailability of 77%) intolerance to drugs. Using during inpatient treatment allows PASCONAT in comprehensive to decrease the administered dose

25 ANTIPROTOZOAL DRUGS ANESTHETICS

METRONIDAZOLE NOVOCAINE 0,25% and 0,5% solution

Antibacterial antiprotozoal drug for systemic administration

How supplied: How supplied: 500 mg/100 ml vials. 200 ml and 400 ml vials.

26 CLINICAL NUTRITION

AMINOL® GLUXYL®

The basis of effective parenteral feeding: optimal source of carbohydrates necessary for mastering of amino-acids

How supplied: How supplied: 100, 200 and 400 ml vials. 200 ml and 400 ml vials.

GLUXYL is a carbohydrate pyruvate and glucose levels. One A balanced complex of L-forms of dispensable and indispensable component of parenteral feeding. of the obligatory conditions for aminoacids for parenteral feeding. Contains xylytol, glucose, sodium effective parenteral feeding is the acetate and a balanced complex concurrent administration of plastic of electrolytes. Quickly absorbed in material donors (AMINOL) and patients with normal metabolism energy donors (GLUXIL). and under stress (xylytol enhances glucose utilization) and does not increase the blood plasma lactate,

27 ANTIVIRAL PREPARATIONS

AKK®

A reliable barrier against flu and cold!

АKK has an evident antiviral action, For the purpose of flu and ARVI prevents contamination and blocks profilaction AKK should be use virus propagation. АKK hampers intranasal pour 2-3 drops 4-5 times penetration of flu A and B viruses, a day; For purpose of treatment - herpes, RS-virus, adenovirus and every 3 hours. arbovirus in human cells. Course of treatment lasts 3-7 days. AKK improves the cellular and humoral indexes of specific and The drug is suitable for newborns. nonspecific defence of organism in case of ARVI. AKK strengthens an immune answer during immunization by influenzal vaccines

How supplied: 10 disposable containers of 2 and 5 ml.

28 ANTIFUNGAL DRUGS

FLUCONAZOLE FLUCONAZOLE 400 мг

A unique decision of The most effective the problem antifungal drug of fungal infections

How supplied: How supplied: 100 mg/50 ml and 200 mg/100 ml vials. 400 mg/200 ml vials.

Fluconazole is the drug of choice Intravenous administration for fungal infections of various of fluconazole ensures high Most effective in case of: • generalized fungal infections in localization caused by Candida effectiveness against fungal • severe hospital fungal infections; oncologic patients concurrent with chemo- and roetgen therapy. fungi, including candidemia. infections of various localization, • fungal infections in intensive care minimal treatment duration for unit patients; • fungal infections caused by The prolonged elimination half-life acute uncomplicated disease forms, resistant fungi. • systemic candidosis (including of the drug – 30 hours – allows to and a high anti-relapse effect. administer it only once daily. fungemia); • opportunistic fungal infections in patients with HIV/AIDS;

29 IRRIGATION SOLUTIONS

TURUSOL® DEKASAN - CYTOCLIN™

Non-hemolizing solution for endoscopy

How supplied: How supplied: 1000 ml, 3000 ml and 5000 ml polymer containers. 1000 ml polymer containers.

1000 ml of solution containes: • optically translucent; Sorbitol - 27 g, Mannitol - 5,4 g in water for injections. • sterile, apyrogenic, constant composition (officinal) Turusol corresponds to the requirements posed to Turusol is used as irrigation solution during realization irrigation solutions: of diagnostic and surgical interferences in urology, ginecology, orthopaedia-traumatology (TURP, • does not contain electrolytes; hysteroscopy, arthroscopy etc.). • ostomotically adapted;

30 IRRIGATION SOLUTIONS

CYTOCLIN™

Sodium chloride-Cytoclin sol., Glukose-Cytoclin sol., Ringer's-Cytoclin sol., Ringer's lactate-Cytoclin sol., Decasan-Cytoclin sol. How supplied: 1000 ml, 2000 ml, 3000 ml and 5000 ml polymer containers.

CYTOCLIN™ is a system for irrigation providing a comfort and safety of medical equipment. and washing. the use both in in-patient terms and in extreme situations. CYTOCLIN™ solutions produced in the polymeric containers of high- Used as an irrigational liquid volume: 500, 1000, 2000, 3000 and at endoscopic manipulations, 5000 ml, that is an additional factor, washings of cavities, and also

31 ACCESSORIES FOR INFUSION THERAPY

SOLUVEN™

Sodium chloride-Soluven sol., Glukose-Soluven sol., Ringer's-Soluven sol., Ringer's lactate-Soluven sol. How supplied: 50 ml, 100 ml, 200 ml and 400 ml polymer containers

SOLUVEN™ is the closed system of for intravenous introduction. Systems SOLUVEN™ made from quick-preparing of solutions. polymeric materials, that is the The use of the SOLUVEN™ system additional factor of providing of The feature of the system is eliminates possibility of hit of safety of the use both in hospital complete closed, emergency safety, medical preparation in an external terms and in extreme situations on comfort, simplicity and quickness of environment, contact of personnel the outpatient stage of providing of process of preparation of solutions or patient with it. medicare.

32 MEDICAL PRODUCTS

SYSTEMS FOR INTRAVENOUS SYRINGES YURiA-PHARM WITH TWO NEEDLES INFUSIONS YURiA-PHARM

Unique high quality patented 3-component syringes with two needles

Yuria-Pharm 3-component syringes are supplied with 2 needles of different size: • the larger needle is attached to the syringe and is recommended for the intake of the medication solution from the container; • the smaller needle, supplied with the syringe, is recommended for the injection. Using the Yuria-Pharm syringes supplied with two different-sized the medication solution; Intravenous drug administration systems needles ensures: are divided into two fundamentally different • the option to perform the injection groups: • maintaining sterility during with a sharp needle, and not the one injection; that was used for the intake of the 1. Infusion systems are used for administration of solutions; • the option to choose the suitable medication solution; needle diameter; • cost saving when purchasing a 2. Transfusion systems are used for blood and blood component transfusions. • the option to use a smaller syringe with two needles compared diameter needle for injections for to a separate purchase of a one- children; needle syringe and an extra needle. • the option to use the larger diameter needle for easier intake of

33 FOR NOTES

34 FOR NOTES

35 YURiA-PHARM LTD 10, Amosova street, Kyiv, Ukraine, 03680 tel/fax: +38 (044) 246-8191, 246-8383 www.uf.ua

Leader of intravenous drugs market in Ukraine and CIS ISO 9001: 2009