Rabbit Anti-Human MMP17 Polyclonal Antibody (DPABH-14336) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Rabbit Anti-Human MMP17 Polyclonal Antibody (DPABH-14336) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Immunogen A synthetic peptide of human MMP17

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Affinity purification

Conjugate Unconjugated

Applications WB

Format Liquid

Size 50ul, 100ul

Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Preservative 0.02% Sodium Azide

Storage Store at -20°C. Avoid freeze / thaw cycles.

BACKGROUND

Introduction This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been

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Keywords MMP17; matrix metallopeptidase 17 (membrane-inserted); MT4-MMP; matrix metalloproteinase- 17; MMP-17; MT4MMP; MTMMP4; MT-MMP 4; membrane-type matrix metalloproteinase 4; membrane-type-4 matrix metalloproteinase; matrix metalloproteinase 17 (membrane-inserted);

GENE INFORMATION

Entrez Gene ID 4326

UniProt ID Q9ULZ9

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