The film’s tail credits begin with a title card that progressively pops up paragraphs of information, beginning this way …

… and ending with the full card …

This film was completed at the end of 1992 and so far …

Doctors all over the world have begun to prescribe Lorenzo’s Oil. If a diagnosis is made early enough the treatment stops the disease. So there is now a growing army of boys kept free from the ravages of ALD.

In recognition of this, Augusto Odone has received an honorary medical degree. He and Michaela continue to raise funds and drive the scientific task force known as ‘The Myelin Project’.

The Shaking Pups are successfully growing new Myelin. This means that human trials will begin within a year. There are many waiting to receive the first brain cell transplants.

Among them is Lorenzo Michael Murphy Odone.

Title: Meanwhile …

Lorenzo is 14 years old.

He is now able to move his head from side to side He has recovered his eyesight and begun to vocalize simple sounds.

He is learning to communicate by means of a computer.

And so he waits, for what will come next.

CAST

Augusto Odone Nick Nolte Michaela Odone Susan Sarandon

Professor Nikolais Peter Ustinov Deidre Murphy Kathleen Wilhoite

Doctor Judalon Gerry Bamman Wendy Gimble Margo Martindale

Ellard Muscatine James Rebhorn Loretta Muscatine Ann Hearn

Omouri Maduka Steady Comorian Teacher Mary Wakio Don Suddaby Don Suddaby Jake Gimble Colin Ward

Nurse Ruth La Tayna Richardson Nurse Nancy Jo Jennifer Dundas

Pellerman William Cameron Pellerman’s Secretary Becky Ann Baker The Librarian Mary Pat Gleason Clown David Shiner

Pediatrician (sic) Ann Dowd Immunosuppression Doctor Peter Mackenzie Professor Duncan Paul Lazar Young Teacher Laura Linney Judalon’s Nurse Helena Ruoti Judalon’s Resident Luis Ruiz Columnist Joyce Reehling Nikolais’ Secretary Barbara Poitier Principal Mary Schmidt Campbell School Psychologist Michael O’Neill Ear Specialist William Thunhurst, Jr. Dietician Ann McDonough Smiling Nurse Lianne Kressin World Bank Executive Nicolas Petrov Suddaby’s Senior Manager Richard Cordery Suddaby’s Junior Manager Angus Barnett Japanese Translator Keiko McDonald Russian Translator Vladimir Padunov Father Killian David McFadden Cristina Odone Carmen Piccini Francesco Odone Aaron Jackson Female Lab Voice Neri Kyle Tannenbaum Male Lab Voice Brad Einhorn

Lorenzo Played By

Noah Banks E. G. Daily Michael Haider Billy Amman Cristin Woodworth Zack O’Malley Greenburg

Murphy Family Played By

Sandy Gore Nora Dunfee Rocco Sisto Amelia Campbell April Merscher Keith Reddin

Symposium Doctors

Eliot Brinton James Merrill Ayub Ommaya Marie Nugent-Head Ryonosuke Shiono Zahra Ilkanipour

Conference Parents

Nancy Chesney Nona Gerard John Mowod David Doepken Susan Chapek Kathryn Aronson Shirley Tannenbaum Lamont Arnold Charles R. Altman Julie Marie Remele Anthony Dileo Annie Loeffler Berta van Zuiden Lisa Montgomery

Special Children

Raina Clifford Nicholas Wiese Todd Bella Tia Delaney Rachel Jones Lamar Olivis Matthew Pyeritz Ryan Thomas Daniel W. D’Arcy Connie Cranden Justin Isfeld C. Alex Roberts Jeremy Beyer Mack Hegyes Christine Merriman Eric Kunkle

CREW

Unit Production Manager Chris Brigham

First Assistant Director Steven E. Andrews

Second Assistant Director Phillip A. Patterson

Financial Controller Catherine Barber

Production Supervisor Europe & Africa Robin Douet

Associate Producers Johnny Friedkin Daphne Paris Lynn O’Hare

Location Manager Neri Kyle Tannenbaum Production Coordinator Ellen Hillers Script Supervisor Daphne Paris

Art Director Dennis Bradford Set Decorator Karen A. O’Hara Lead Dresser Ken Turek Property Master Brad Einhorn Assistant Property Master Andrew M. Seigel Additional Art Direction John Wingrove

Construction Coordinator S. Bruce Wineinger Master Scenic Artist Eileen Garrigan

Make-up Artists Fabrizio Sforza David Craig Forrest

Hair Design Paul Leblanc

Wardrobe Supervisors Linda Matthews David Davenport

Camera Operator Brian W. Armstrong

First Camera Assistant Bobby Mancuso Second Camera Assistant Brian S. Osmond

Gaffer Reg Garside Best Boy Electric Andy Nelson Second Electric Rick Maddux

Key Grip Robin Knight Best Boy Grip Dennis Kuneff Dolly Grip Chuck Brown

Publicity Johnny Friedkin Still Photographer Mikki Ansin

Desaturation Effects Roger Cowland

Production Sound Mixer Ben Osmo

Post Production Sound Mixer Roger Savage

Sound Design Lee Smith

Assistant Accountant Katie Clarke Assistant Production Coordinator Jessica L. Abrams Assistant to George Miller Dawn Murphy Riley

Assistant Location Manager Annie Loeffler Location Assistant Fred Sandusky

Location Scout & Special Casting Carol McClenahan

Assistant Art Director Michael Kuhling Assistant to the Decorator Diana L. Stoughton Art Department Coordinator Francine Byrne Draftsman Gary Kosko

Assistant Costume Designer Kathleen Gerlach Assistant Make-up Artist Alessandra Sampaolo Assistant Hair Stylist Jeffrey A. Rubis

Greenskeepers Stephanie Waldron Marty Garrigan

On-set Dressers Edwin Lohrer, III Mia Boccella Dressers Edward F. West Catherine Stanton James D. Kempf

Construction Foreman Steve Willis Construction Assistant Danielle Norman Prop Maker Foremen Michael Maxson Ronald Lee Hiatt Labor Foreman Ronald Alston

Stand-by Scenic Artist Paula Payne Second Scenic Artist Frika Gray

Special Effects John D. Milinac

Visual Effects Photographer Matt Butler

Body Prosthetics Designer Tom Hester Prosthetics Consultant Rick Baker Special Prop Construction Clay Pinney

Pittsburgh Casting Canice Kennedy Casting Associate Christine Sheaks A.D.R. Voice Casting Barbara Harris Voice Consultant to Susan Sarandon Nora Dunfee Dialectician to Nick Nolte Bill Dearth Nolte Conspirator Bill Cross Italian Coach Carmen Piccini Tutor Marla Jonas

Electricians Peter Bennett Beal John A. Roush Jim Petri Company Grips James P. Gribbins Joseph Wrubleski

Boom Operators Terence J. O’Mara Jerome R. Vitucci

Key Production Assistant Andrew Bernstein

Production Assistants

Katia Lund Robert Pomeroy Frederick E. Kowalo Elizabeth Trevan Laura Hamilton Barbie Pastorik John O. Hartman Jnr Elizabeth Hiebner Rand Templeton Chris Anne Downes

Scenic Artists

Nora Cline Pam Lewis Leah Blackwood Cathy Bruce Vince Borrelli Kathy Borland Michele M. Misiti Mary O’Brien

Transport

Mario Simon George Bolton Chip Vincent Pat Mahoney

Washington Office Coordinator Allison Sherman Washington Location Scout Kevin Brubaker

Catering By Gala Catering

U. K. Support Crew Designer Jamie Leonard Production Manager Joanna Gollins Location Manager Liz Kerry Casting Debbie McWilliams

Italian Support Crew

Production Supervisor Claudio Mancini Production Manager Franco Coduti Unit Manager Alessandro Mancini Production Coordinator Cinzia Taffani Permissions Campanella First Assistant Director Phillip Patterson Set Dresser Bruno Cesari Casting Chiara Meloni Gaffer Alvaro Romagnoli Key Grip Aldo Colanzi

African Support Crew

Location Manager Robin K. Hollister Liaison Anne Waudo First Assistant Director John Chavanga Second Assistant Director Leonard Juma Focus Puller Steve Burgess Clapper/Loader Richard Tindall Designer Jamie Leonard Set Dresser Annelise Archer Prop Master J. F. Chavrier Construction Manager Jimmy Mukora Costume Supervisor Kirsten Heckterman Make-up & Hair Suzy Belcher Fiona Musselwhite Cashier Herman Mbugua Local Gaffer Alan Barry Key Grip Paul Thompson Camera Technician Shanni Chaggar Boom Operator Gerry Nucifora

Post Production Crew

Post Production Supervisor Marcus D’Arcy Additional Picture Editing Lee Smith First Assistant Editors Paula Lourie Jane Maguire

Assistant Editors Rick Lisle Jane Moran Leilani Hannah Patricia A. Galvin Carol A. Fleming Kimberly Walls

A.D.R. Editor Annabelle Sheehan

Dialogue Editors Livia Ruzic Wayne Pashley

Sound Editor Gareth Vanderhope Additional Sound Editors Peter Townend Tim Jordan Foley Editors Steve Burgess Jerry Long Atmos Editor Julius Chan Additional Mixer Ian McLoughlin

Music Supervisor Christine Woodruff

End Credit Sequence Margaret Sixel

Sound Studio Soundfirm Liaison Liz Wright

EDI-TRACKER - logo

Opticals Roger Cowland Ken Phelan

Grading Arthur Cambridge Tony Manning Titles & Supers Optical & Graphic Title Design Artlantis Neg Matcher Karen Psaltis Laboratory Atlab Australia Technicolor A.D.R. Mixer Bob Deschaine A.D.R. Recordist David Jobe A.D.R. Additional Mixer Paul Zydel

Kennedy Miller Support Staff

Lynda Collings Barbara Nolan Alfonso Valencia

Special Thanks

Michael and Mary Haider Gale Edwards National Society of Genetic Counselors Inc.

Article from Archives of Neurology Vol. 32 September 1975, pp: 577-579 Copyright © 1975 American Medical Association

Illustration from “Human Anatomy and Physiology”, 5th Ed. Copyright © 1990 WM C. Brown Communications, Inc.

Illustration from “Anatomy: A Regional Atlas of the Human Body” 3rd. Ed. Copyright © 1987 Urban & Schwarzenberg

Reading from “The Complete Adventures of Peter Rabbit” by Beatrix Potter. Published by Frederick Warne/Penguin Books Ltd

Mark de Freis Scientific Hospital The Estate of Keith Haring Tova Laiter and Imagine Films Entertainment, Inc. Shirley Bates and WB Travel Bon Bon Entertainment, Inc. Luis Lecarre Howard Fabrick

Music

KIJANA MWANA MWALI written by Idylio Cortini/Roberto Marini, performed by Gonda Traditional Entertainers courtesy Tropical Recording and Promotion Pty Ltd

Verdi, LA TRAVIATA - “PARIGI, O CARA” performed by Joan Carden and Richard Greager, The Elizabethan Sydney Orchestra conducted by , courtesy The Australian Opera

Georgy Sviridov, THREE CHORUSES TO THE PLAY, “TSAR FEODOR IOANNOVICH” used by permission Boosey & Hawkes Music Publishers Ltd performed by Gloriae Dei Cantores, courtesy Gloriae Dei Cantores Mahler, SYMPHONY NO. 5 IN C SHARP MINOR performed by Royal Concertgebouw Orchestra of Amsterdam, conducted by Bernard Haitink courtesy Philips Classics distributed by PolyGram Pty Limited

Barber, ADAGIO FOR STRINGS used by permission G. Schirmer (Australia) Pty Ltd performed by City of London Sinfonia, conducted by Richard Hickox, courtesy Virgin Classics Ltd performed by Philharmonia Virtuosi, conducted by Richard Kapp, courtesy Sony Music Pty Ltd

Barber, ANGUS DEI used by permission G. Schirmer (Australia) Pty Ltd, performed by the Corydon Singers, conducted by Matthew Best, courtesy Hyperion Records Limited

Bellini, NORMA - CASTA DIVA performed by Maria Callas, Orchestra and Chorus of La Scala Opera House, Milan, conducted by Tullio Serafin, courtesy EMI Records Ltd

Bellini, NORMA - Introduction to Act II Orchestra of La Scala Opera House, Milan, conducted by Tullio Serafin, courtesy EMI Records Ltd

Marcello, A., OBOE CONCERTO IN D MINOR performed by Malcolm Messiter with the Guildhall String Ensemble, courtesy BMG Classics

Verdi, MASS - “AGNUS DEI” Leontyne Price/Vienna Musikverein/Vienna Philharmonic Orchestra, conducted by Fritz Reiner courtesy Decca Recording Co Ltd distributed by PolyGram Pty Limited

Donizetti, L’ELISIR D’AMORE - “UNA FURTIVA LAGRIMA” Introduction performed by Orchestra Sinfonia della RAI di Torino conducted by Claudio Scimone, courtesy Philips Classics distributed by PolyGram Pty Limited aria performed by Tito Schipa, Orchestra of La Scala Milan conducted by Carlo Sabajno

Elgar, CELLO CONCERTO IN E MINOR, Op. 85 performed by Michaela Fukačová, and Brno State Philharmonic Orchestra conducted by Libor Pešek, courtesy Supraphon Recording Co. DDD

THE LITTLE DRUMMER BOY (Davis/Simeone/Onorati) (C) 1959 Mills Music Inc/Delaware Music Corp used by kind permission of Warner Chappell Music Ltd, performed by the Daughters of St Paul, courtesy Daughters of St Paul, courtesy Daughters of St Paul, Boston MA

ANDACHSTJODLER settings by Josef Döller, performed by The Vienna Boys Choir/Wiener Volksopernorchester conducted by Uwe Christian Harrer, courtesy Philips Classics distributed by PolyGram Pty Limited

Mozart, AVE VERUM CORPUS KV 618 performed by Symphonieorchester des Bayerischen Rundfunks, conducted by Leonard Bernstein courtesy Deutsche Grammophon distributed by PolyGram Pty Limited

Original Soundtrack on MCA CD’s and Cassettes

Location Equipment by General Camera Corporation

Lighting Equipment and Production Van supplied by Matthews Group/Hollywood Rental Company, Inc

Panaflex Camera and Lenses by Panavision

Dolby Stereo ® In Selected Theatres - logo

This picture made under the jurisdiction of IATSE - logo Affiliated with A.F.L. - C.I.O. - C.I.C.

Certificate No. 32047 logo ® Motion Picture Association of America

Copyright © 1992 Universal City Studios, Inc. All Rights Reserved

Country of first publication: United States of America Kennedy Miller Films Pty. Limited is the author of this motion picture for purposes of the Berne Convention and all national laws giving effect thereto.

This is a true story, although certain characters and incidents are fictional.

This motion picture is protected under the laws of the United States and other countries. Unauthorised duplication, distribution or exhibition may result in civil liability and criminal prosecution.

The Myelin Project 1 − 800 − 8MYELIN