Bridging the Gap
Advanced Breast Cancer
2-4 November 2017 Fourth Lisbon, Portugal Coordinating Chair: ESO-ESMO F. Cardoso, PT Chairs: International E.P. Winer, US - L. Norton, US - A. Costa, IT/CH Co-Chairs: Consensus E. Senkus, PL - E. Papadopoulos, CY Scientific Committee Members: Conference M.S. Aapro, CH - F. André, FR - N. Harbeck, DE
The ABC4 conference is held The ABC4 conference and guidelines are endorsed by with support from under the auspices of with official and is endorsed by The ABC4 guidelines will be representatives of FEDERACIÓN developed by ESO and ESMO LATINOAMERICANA DE MASTOLOGIA
ABC4 will be followed by the first meeting of the on 4-5 November 2017
THIRD ANNouNCemeNT Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference Dates and Team
Dolores Knupfer (2) Passed (28 April 2017) ABC Award nominations [email protected]
Submit online at www.abc-lisbon.org Passed (15 May 2017) Abstract submission Luis Carvalho (2) [email protected]
Dolores Knupfer (2) Passed (15 May 2017) Travel grant applications [email protected]
Passed (30 July 2017) Early registration Register online at www.abc-lisbon.org By 15 October 2017 Late registration Laura Richetti (2) [email protected] After 16 October 2017 On-site registration Luis Carvalho (2) [email protected]
Accommodation, optional tours Helder Carvalho (3) By 28 October 2017 and social event [email protected]
Organisation, exhibition, Francesca Marangoni (1) satellite symposia and sponsorship [email protected]
Dolores Knupfer (2) [email protected] Dedicated Programme secretariat media partner Alexandra Zampetti (2) [email protected]
Corinne Hall (1) Social media [email protected]
Gabriele Maggini (2) Communication [email protected]
International media: Emma Mason and Kerry Noble [email protected] 5VIWWSǽGIVW Partner journal National media: Filipa Morais [email protected] THE BREAST Chatrina Melcher (2) An Associate Journal of the Australasian Society for Breast Disease Affiliated with the European Society of Breast Cancer Specialists Official Journal of the Breast Centres Network Coordination [email protected]
ph +39 02 85464 532 1 European School of Oncology fx +39 02 85464 545 Via Turati 29 www.abc-lisbon.org 20121 Milano, Italy www.eso.net ph +41 91 820 0950 2 European School of Oncology fx +41 91 820 0953 Piazza Indipendenza 2 www.abc-lisbon.org 6500 Bellinzona, Switzerland www.eso.net
3 Viagens Abreu SA TL ccc eƴţƤƖĂÚåeÆųĜĬØƖ J\ cc 2799-556 Linda-a-Velha, Portugal
ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 2 #ABClisbon
Dear Colleagues,
he International Consensus Conference for Advanced Breast Cancer (ABC) has established itself as a major international breast cancer conference. Its primary aim is the development of international consensus guidelines for the management of ABC patients. These guidelines are based on the most Tup-to-date evidence and can be used to guide treatment decision making in many different health care settings globally, with the necessary adaptations due to different access to care.
The last meeting, which took place in Lisbon, Portugal in November 2015, brought together over 1.200 participants from 84 countries around the world, including health professionals, patient advocates and journalists.
We believe that health professionals working closely together with patient advocates and with the strong support of media can raise awareness about the needs and challenges faced by this traditionally underserved and forgotten group of patients. ABC also aims to identify research priorities based on the most important areas of unmet need, analyse and discuss available data to provide the most accurate management recommendations, as well as influence policy makers and funding bodies and ultimately improve standards of care, survival and quality of life. Research and education, with accurate usage of available knowledge, throughout the world, are key to achieve these goals.
ABC guidelines are jointly developed by ESO (European School of Oncology) and ESMO (European Society of Medical Oncology) and guidelines or ABC conferences have been endorsed and supported by several other international oncology organizations such as EUSOMA (European Society of Breast Cancer Specialists), ESTRO (European Society of Radiation Oncology), ESGO (European Society of Gynaecological Oncology), UICC (Union International Contre le Cancer), SIS (Senologic International Society) / ISS (International School of Senology), FLAM (Federacion Latino- Americana de Mastologia), OECI (Organization of European Cancer Institutes), Susan G. Komen® and BCRF (Breast Cancer Research Foundation), and have official representation from ASCO.
The recent creation of the ABC Global Alliance, will also provide a much needed platform for the development of important projects, aiming to strongly impact on the survival and quality of life of advanced breast cancer patients.
It is therefore with great enthusiasm that we invite you to attend the Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference (ABC4) that will take place in Lisbon, Portugal, on 2-4 November 2017, which will be followed by the first meeting of the ABC Global Alliance on 4 and 5 November 2017.
Fatima Cardoso, Coordinating Chair
LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 3 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference General information
Venue Filming, recording or photographing Conference ABC4 will be held at the CCL - Centro de Congressos sessions de Lisboa, Praça das Industrias, Lisbon, Portugal. Filming, recording or photographing Conference sessions is prohibited, unless prior permission has been official language sought and agreement obtained from the press officers. The official language will be English. No translation will Filming, recording or photographing in the general areas be provided. of the Conference is permitted if prior permission has been sought and agreement obtained from the press Insurance officers. The organisers bear no responsibility for untoward events in relation to the participation in the Conference. Social media Participants are advised to take out their own personal Follow updates and send questions to our onsite Social and travel insurance coverage. Media Moderators using #ABClisbon on Twitter and Facebook and join in Abstract book the discussions. The abstract book will be published as a supplement of The Breast and contain abstracts of the invited lecturers Third Party media Policy and those submitted by the participants that have been The policy that applies to all activities related to the accepted for oral or poster presentation or for news media during or in connection with ABC4 and is publication only. The abstract submission deadline has posted at www.abc-lisbon.org/pagine-interne/third- passed party-media-policy.html (15 May 2017). The aim is to ensure that information distributed to the journalists is accurate and is issued at the correct times, Travel grants complying with any embargoes that may be in place. Travel grants were made available on a competitive basis The policy applies to media events that are organised at to: the ABC4 venue and off-site, and all third parties are - Physicians from middle- and low-income countries as requested to adhere. defined by The World Bank; - Physicians under the age of 40; No smoking policy - Nurses; ABC4 is a tobacco-free event. All participants are kindly - Patient advocates. asked to respect the no-smoking policy. The application deadline has passed (15 May 2017). official carrier Cme accreditation and certificates TAP Portugal, a Star Alliance member, Participants will be entitled to receive a certificate of is pleased to be appointed as the attendance at the close of the Conference by ABC4 Official Carrier and offers completing the online evaluation questionnaire. discounts (10% on economy and 15% The event has been accredited by the on business class fares) to European Accreditation Council for participants who make their flight booking on TAP Continuing Medical Education (EACCME) to Portugal flights through TAP Portugal’s website. provide the following CME activity for To make the booking, the participant should follow medical specialists. The EACCME is an these steps: institution of the European Union of Medical Specialists - enter the website www.flytap.com (UEMS). The evaluation of the event has been - select flights and dates (dates should be within 10 days performed by the Accreditation Council of Oncology in before and 10 days after the event) Europe (ACOE) that acknowledged the quality of the - insert the event code IT17TPCG100 in the scientific programme and its educational value. Promotion/Congress Code Box, located on the left side The event is designated for a maximum of 15 of the webpage european Cme credits (eCmeC). Through an agreement between UEMS and the Please note that not eligible for TAP discounts are American Medical Association, physicians bookings made previously through travel agencies or at may convert EACCME credits to an TAP desks and code-share flights operated by other equivalent number of AMA PRA Category 1 Credits™. airlines. Furthermore, the conference has been accredited with 17 eSmo- moRA category 1 points.
ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 4 #ABClisbon High Patronage
The European School of Oncology is proud to announce that the Conference is held under the High Patronage of His Excellency the President of the Portuguese Republic
ABC4 Scientific Committee
Coordinating chair Chairs Fatima Cardoso eric P. Winer Breast Unit, Breast Oncology Center, Champalimaud Clinical Center, Dana-Farber Cancer Institute, Lisbon, PT Boston, US Larry Norton Co-chairs Breast Cancer Programs, elzbieta Senkus Memorial Sloan-Kettering Cancer Centre, Dept. of Oncology and Radiotherapy, New York, US Medical University of Gdansk, Gdansk, PL Alberto Costa European School of Oncology, evi Papadopoulos Milan, IT and Bellinzona, CH Europa Donna, Nicosia, CY Scientific Committee members matti S. Aapro MO Clinique de Genolier, Institut Multidisciplinare d’Oncologie, Genolier, CH Fabrice André Department of Medical Oncology, Gustave Roussy Institute, Villejuif, FR Nadia Harbeck Breast Centre, University of Munich, Munich, DE
ABC4 is held in memory of … Doris Fenech, a passionate breast cancer nurse, a dedicated patient advocate and an advanced breast cancer patient who strongly believed in and supported the ABC Consensus Conferences serving in its committee from the beginning.
LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 5 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference Faculty members Bertha Aguilar Lopez Lesley Fallowfield ULACCAM, Mexico City, MX Sussex Health Outcomes Research & Education in Carlos H. Barrios Cancer, Brighton & Sussex Medical School, University of Department of Medicine, PUCRS School of Medicine, Sussex, Brighton, UK Porto Allegre, BR Prudence A. Francis Jonas Bergh Division of Cancer Medicine, Peter MacCallum Cancer Department of Oncology-Pathology, Karolinska Institute, Centre, Melbourne, AU Stockholm, SE Karen Gelmon elizabeth Bergsten Nordström Department of Medical Oncology, BC Cancer Agency, Swedish Breast Cancer Association, Stockholm, SE Vancouver, CA Laura Biganzoli mary K. Gospodarowicz Department of Medical Oncology, Sandro Pitigliani Department of Radiation Oncology, Princess Margaret Oncology Centre, Prato, IT Hospital, University of Toronto, Toronto, CA Christine B. Boers-Doets Renate Haidinger CB Boers ORG. Wormer, NL and The Netherlands Leiden Brustkrebs Deutschland e.V., Munich, DE University Medical Center, Leiden, NL Stephen R.D. Johnston Anna Cabanes Breast, Lung & Medical Oncology Services CBU, The Susan G. Komen, Washington, US Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, UK maria João Cardoso Breast Unit, Champalimaud Cancer Center and Bella Kaufman MamaHelp, Lisbon, PT Oncology Institute, Sheba Medical Center, Tel Hashomer, IL Lisa A. Carey Smruti Koppikar Department of Hematology and Oncology, UNC Department of Oncology, Bombay Hospital Institute of Lineberger Comprehensive Cancer Center, North Medical Sciences, Lilavati Hospital and Asian Cancer Carolina, US Institute, Mumbay, IN Dian “CJ” m. Corneliussen-James Ian e. Krop METAvivor Research and Support, Annapolis, US Breast Oncology Center, Dana-Farber Cancer Institute, Boston, US Javier Cortés Ramón y Cajal University Hospital, Madrid & Vall Danni manzi d’Hebron Institute of Oncology (VHIO), Madrid, ES Breast Cancer Care, London, UK Giuseppe Curigliano Norbert marschner Division of Experimental Therapeutics, European Department of Hematology and Oncology, Outpatient Institute of Oncology, Milan, IT Cancer Center, Freiburg, DE Véronique Diéras musa mayer Gynaecology and Breast Department, Centre Eugène Metastatic Breast Cancer Alliance, New York, US Marquis, Rennes, FR Shirley A. mertz matthew J. ellis Metastatic Breast Cancer Network US, Inverness, US Lester and Sue Smith Breast Center, Baylor Clinic, Gertrude Nakigudde Houston, US Uganda Women’s Cancer Support Organisation, Nagi S. el Saghir Kampala, UG NK Basile Cancer Institute, American University of Beirut Birgitte V. offersen Medical Center, Beirut, LB Department of Oncology, Aarhus University Hospital, DK Alexandru eniu Shinji ohno Department of Breast Tumors, Cancer Institute “I. Breast Oncology Centre, Cancer Institute Hospital, Tokyo, JP Chiricuta”, Cluj-Napoca, RO
ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 6 #ABClisbon
olivia Pagani George W. Sledge Breast Unit, Oncology Institute of Southern Switzerland, Division of Oncology, Stanford School of Medicine, Bellinzona, CH Stanford, US Shani Paluch-Shimon Danielle Spence Oncology Institute, Shaare Zedek Medical Centre, Breast Cancer Network Australia, Camberwell, AU Jerusalem, Israel, IL Christoph Thomssen Frédérique Penault-Llorca Clinic for Gynaecology, Martin-Luther-Universität, Department of Pathology, Jean Perrin Centre, Klinikum Kröllwitz, Halle (Saale), DE Comprehensive Cancer Centre, Clermont Ferrand, FR Nicholas Turner Aleix Prat Breakthrough Breast Cancer Research Centre at the Hospital Clínic of Barcelona, University of Barcelona, Institute of Cancer Research, London, UK Barcelona, ES Daniel A. Vorobiof Hope S. Rugo Sandton Oncology Centre, Johannesburg, ZA Breast Oncology and Clinical Trials Education, UCSF Nikhil Wagle Helen Diller Family Comprehensive Cancer Center, San Harvard Medical School, Dana-Farber Cancer Institute, Francisco, US Boston, US Timo Schinköthe Binghe Xu CANKADO, Munich, DE Department of Medical Oncology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, CN ABC4 conference and consensus guidelines
The ABC guidelines are jointly developed by ESO and ESMO and are published simultaneously in The Breast and Annals of Oncology journals. The Conference is endorsed by EUSOMA, FLAM, SIS/ISS, ESTRO, held with the support from BCRF and Susan G. Komen, under the auspices of OECI, UICC and with official representatives of ASCO. The guidelines are endorsed by EUSOMA, FLAM, SIS/ISS and will be submitted for endorsement to ESTRO. Details about the publication of the previous editions’ guidelines at www.abc-lisbon.org
FEDERACIÓN LATINOAMERICANA DE MASTOLOGIA
LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 7 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference ABC Award
he ABC Award is aimed at recognising a researcher, physician, nurse or patient advocate who has made an Toutstanding and impacting contribution in the field of advanced breast cancer throughout his/her career.
The third ABC Award - in recognition for her work and dedication to advocacy specifically to advanced breast cancer patients will be assigned to musa mayer during the Award Ceremony on Thursday, 2 November.
The second ABC Award - in recognition for his work on metastatic breast cancer, especially improving the management of metastatic cancer to bone, resulting in preservation and improvement in quality of life of patients worldwide - was assigned to Robert E. Coleman.
The first ABC Award - in recognition of his work on discovering fundamental, clinically- relevant biological and molecular mechanisms for metastases including site specificity, latency, self-seeding and the role of the microenvironment in colonization and drug resistance - was assigned to Joan Massagué.
ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 8 #ABClisbon Breast Cancer Patient Advocacy
epresentatives of breast cancer patient advocacy groups are warmly invited to participate in ABC4 and actively contribute to the scientific programme and consensus session. RFurthermore, in collaboration with the Breast Cancer Patient Advocacy Committee, including several leading breast cancer patient advocacy groups worldwide, specific additional patient advocacy sessions have been scheduled.
Breast Cancer Patient Advocacy Committee:
Metastatic Breast Cancer Awareness, Research and Support
Coordinator: Fatima Cardoso Breast Unit, Champalimaud Cancer Center, Lisbon, PT
Bertha Aguilar Lopez musa mayer ULACCAM, Mexico City, MX Metastatic Breast Cancer Alliance, New York, US Anna Cabanes Shirley A. mertz Susan G. Komen, Washington, US Metastatic Breast Cancer Network US, Inverness, US maria João Cardoso Gertrude Nakigudde MamaHelp Association, Lisbon, PT Uganda Women’s Cancer Support Organisation, Dian “CJ” m. Corneliussen-James Kampala, UG METAvivor Research and Support, Annapolis, US evi Papadopoulos Renate Haidinger Europa Donna, Nicosia, CY Brustkrebs Deutschland e.V., Munich, DE Danielle Spence Danni manzi Breast Cancer Network Australia, Camberwell, AU Breast Cancer Care, London, UK
LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 9 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference Programme outline
Wed. Thursday, 2 Friday, 3 Saturday, 4 Sunday, 5 1 Nov November November November November 8:30-13:00 Exhibition 9:00-19:30 Exhibition 9:00-19:30 Exhibition 8:30-10:30 9:00-10:30 9:00-10:30 9:00-9:55 Consensus session 9:00-13:00 Patient Sponsored The new management of (part I) First meeting advocacy satellite luminal ABC of the session: symposium ABC Global (SǺIIFVIEO Direct patient Alliance involvement in (part 2) ABC research 10:20-11:30 (SǺIIFVIEO Clinical challenges (SǺIIFVIEO 11:00-12:30 11:00-12:30 11:00-11:15 Patient Sponsored 11:30-12:25 Report from ABC advocacy satellite .RǼEQQEXSV]EHZERGIH Patient Advocacy session: symposium breast cancer Committee Survivorship ;SVO 11:15-12:45 ǻRERGIWLSQI Consensus session and emotional (part II) support
12:25-13:30 Lunch Lunch and poster session 12:45-13:00 Close
13:30-14:30 13:30-14:25 Opening session and Lost in translation! Keynote lecture 14:30-15:25 14:25-15:35 14:30 Lunch Long term remissions: Supportive and Challenges and controversies palliative care 15:00-18:00 15:25-16:05 First meeting of the Best abstract presentations (SǺIIFVIEO ABC Global Alliance (part 1) 16:00-17:00 (SǺIIFVIEO A world of contrasts! 16:30-17:40 Optimizing anti-HER2 17:00-18:00 therapies for ABC Management of 17:40-18:00 triple negative ABC ABC Award and lecture 18:00-19:30 18:00-19:30 18:00-19:30 18:00-19:30 Patient Sponsored Patient Sponsored advocacy satellite advocacy satellite session: symposium session: ABC symposium Registries, Advocacy: databases Managing side and statistical IǺIGXWWI\YEP REGISTRATION OPENS 14:00-17:00 REGISTRATION modelling: issues and QEOMRK2'( fertility count
;IPGSQIGSGOXEMP (included in the registration fee) 3IX[SVOMRKIZIRMRK (not included in the registration fee) A/V Recording during the Conference is prohibited. ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 10 #ABClisbon Programme Thursday, 2 November 2017
9:00-10:30 Patient advocacy session: Audit.II Direct patient involvement in ABC research Chairs: Bertha Aguilar Lopez, MX - Anna Cabanes, US - Shirley A. Mertz, US Panellists: Bertha Aguilar Lopez, MX - Jonas Bergh, SE - Matthew J. Ellis, US Shirley A. Mertz, US - Danielle Spence AU - Nikhil Wagle, US
9:00-10:30 Sponsored satellite symposium 1 (details are available on page 17) Audit. I 10:30-11:00 Coffee break
11:00-12:30 Patient advocacy session: Audit. II Survivorship 101: Work, finances, home and emotional support Chairs: Danni Manzi, UK - Gertrude Nakigudde, UG - Evi Papadopoulos, CY - Work means more than money Evi Papadopoulos, CY - Discussion - The support of the other side Lesley Fallowfield, US - Discusssion - How can I swim in a storm Gertrude Nakigudde, UG - Discussion
11:00-12:30 Sponsored satellite symposium 2 (details are available on page 17) Audit. I 12:30-13:30 Lunch
13:30-14:30 Opening session Audit. I Chairs: Fatima Cardoso, PT and Larry Norton, US - Welcome to Lisbon National authorities - opening and introduction Fatima Cardoso, PT - Keynote lecture-Living two roles: oncologist and patient Bella Kaufman, IL 14:30-15:25 Long term remissions: Challenges and controversies Audit. I Chairs: Anna Cabanes, US and Olivia Pagani, CH - management issues: How and until when to treat? Christoph Thomssen, DE - Is family planning (fertility, adoption) out of the question? Shani Paluch-Shimon, IL - Impact on legal and professional lives Elizabeth Bergsten Nordström, SE - Discussion A/V Recording during the Conference is prohibited. LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 11 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference 15:25-16:05 Best abstract presentations Audit. I Chairs: Alberto Costa, IT/CH and Danielle Spence, AU - Analysis of the gaps on metastatic breast cancer global policies and advocacy efforts to support policy development across the patient journey Maia Thrift-Perry, US - Impact of disease progression status on time to deterioration of patient reportedhealth related quality of life in first line er+ her2-ve advanced/metastatic breast cancer patients in the PALomA-2 study Nadia Harbeck, DE - effect of exercise on cardiovascular fitness and quality of life outcomes in advanced breast cancer patients Eduardo Oliveira, PT - Discussion
16:05-16:30 Coffee break
16:30-17:40 Optimizing anti-HER-2 therapies for ABC Audit. I Chairs: Elzbieta Senkus, PL and Eric P. Winer, US - optimal sequence with and without all availble agents Ian E. Krop, US - overcoming resistance to anti-HeR2 therapies Karen Gelmon, CA - Potential role of immunotherapy Javier Cortés, ES - Will biosimilars become standard? Smruti Koppikar, IN - Discussion
17:40-18:00 ABC Award and lecture Audit. I Silent voices speak: An advocate's journey Chair: Larry Norton, US - Awardee: Musa Mayer, US 18:00-19:30 Patient advocacy session: Audit. II Registries, databases and statistical modelling: Making MBC count Chairs: Musa Mayer, US and Danielle Spence, AU - Introduction and Australia STAR project Danielle Spence, AU - estimation of the number of women living with metastatic breast cancer in the united States Musa Mayer, US - The new German cancer registry Norbert Marschner, DE - Breast Cancer Care uK Danni Manzi, UK - Discussion
18:00-19:30 Sponsored satellite symposium 3 (details are available on page 18) Audit. I
19:30 Welcome cocktail (included in the registration fee)
20:30 Networking evening at a special venue (not included in the registration fee – details on page 22) A/V Recording during the Conference is prohibited. ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 12 #ABClisbon
Friday, 3 November 2017
9:00-9:55 The new management of luminal ABC Audit. I Chairs: Bertha Aguilar Lopez, MX and Binghe Xu, CN - Best sequence of available therapies Nadia Harbeck, DE - management of new side effects Carlos H. Barrios, BR - mechanisms of resistance to endocrine and biological agents Stephen R.D. Johnston, UK - Discussion
9:55-10:20 Coffee break
10:20-11:30 Clinical challenges Audit. I Chairs: Jonas Bergh, SE and Renate Haidinger, DE - metronomic chemotherapy: A good old friend Nagi S. El Saghir, LB - maintenance therapy (CT, eT, biologics) Prudence A. Francis, AU - oral drugs: Challenges for the oncology nurse Christine B. Boers-Doets, NL - ABC elderly patient management Laura Biganzoli, IT - Discussion
11:30-12:25 Inflammatory advanced breast cancer Audit. I Chairs: Maria João Cardoso, PT and Gertrude Nakigudde, UG - Biology of inflammatory breast cancer Frédérique Penault-Llorca, FR - extensive cutaneous metastases: A separate entity? Giuseppe Curigliano, IT - The role of different radiation techniques Birgitte V. Offersen, DK - Discussion
12:25-13:30 Lunch and poster session
13:30-14:25 Lost in translation! Audit. I Chairs: Dian “CJ” M. Corneliussen-James, US and Daniel A. Vorobiof, ZA - multigene testing: Aid or clinical nightmare Fabrice André, FR - The role of ctDNA Nicholas Turner, UK - Precision/personalized medicine: Hopes & hypes George W. Sledge, US - Discussion
A/V Recording during the Conference is prohibited. LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 13 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference
14:25-15:35 Supportive and palliative care Audit. I Chairs: Matti S. Aapro, CH and Musa Mayer, US - management of neurotoxicity Matti S. Aapro, CH - Peritoneal carcinomatosis and ascites: Best practices Véronique Diéras, FR - end-of-life communication: Patient and health care provider perspectives Lesley Fallowfield, UK and Musa Mayer, US - Discussion
15:35-16:00 Coffee break
16:00-17:00 A world of contrasts! Audit. I Chairs: Fatima Cardoso, PT and Shirley A. Mertz, US - Access to radiation worldwide Mary K. Gospodarowicz, CA - Shortage of drugs: Solutions Alexandru Eniu, RO - eHealth: Friend or foe Timo Schinköthe, DE - Discussion
17:00-18:00 Management of triple negative ABC Audit. I Chairs: Shinji Ohno, JP and E. Papadopoulos, CY - What’s new in biology Aleix Prat, ES - The role of immunotherapy Hope S. Rugo, US - New kids on the block: CDKi, ARi, PARPi Lisa A. Carey, US - Discussion
18:00-19:30 Patient advocacy session: Audit. II ABC Advocacy: Managing side effects, sexual issues and fertility Chairs: Dian “CJ” M. Corneliussen-James, US and Renate Haidinger, DE - How can physicians help to avoid or treat side effects? Christoph Thomssen, DE - How can patients help to avoid or treat side effects? Renate Haidinger, DE - Discussion - Intimacy - starting over Dian “CJ” M. Corneliussen-James, US - Fertility - the joys and the risks Dian “CJ” M. Corneliussen-James, US - Discussion
18:00-19:30 Sponsored satellite symposium 4 (details are available on page 18) Audit. I
A/V Recording during the Conference is prohibited. ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 14 #ABClisbon
Saturday, 4 November 2017
8:30-10:30 Consensus session (part I) Audit. I ABC4 chairs, scientific committee members and panellists
10:30-11:00 Coffee break
11:00-11:15 Report from ABC Patient Advocacy Committee Audit. I Danielle Spence, AU
11:15-12:45 Consensus session (part II) Audit. I ABC4 chairs, scientific committee members and panellists
12:45-13:00 Close Audit. I
A/V Recording during the Conference is prohibited.
Consensus panellists
Matti S. Aapro, CH Alexandru Eniu, RO Olivia Pagani, CH Bertha Aguilar Lopez, MX Lesley Fallowfield, UK Shani Paluch-Shimon, IL Fabrice André, FR Prudence A. Francis, AU Evi Papadopoulos, CY Carlos H. Barrios, BR Karen Gelmon, CA Frédérique Penault-Llorca, FR Jonas Bergh, SE Mary K. Gospodarowicz, CA Aleix Prat, ES Laura Biganzoli, IT Nadia Harbeck, DE Hope S. Rugo, US Christine B. Boers-Doets, NL Stephen R.D. Johnston, UK Elzbieta Senkus, PL Fatima Cardoso, PT Bella Kaufman, IL George W. Sledge, US Maria João Cardoso, PT Smruti Koppikar, IN Danielle Spence, AU Lisa A. Carey, US Ian E. Krop, US Christoph Thomssen, DE Javier Cortés, ES Musa Mayer, US Daniel A. Vorobiof, ZA Alberto Costa, IT/CH Gertrude Nakigudde, UG Eric P. Winer, US Giuseppe Curigliano, IT Larry Norton, US Binghe Xu, CN Veronique Diéras, FR Birgitte V. Offersen, DK Nagi S. El Saghir, LB Shinji Ohno, JP
LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 15 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference First meeting of ABC Global Alliance
espite some progress, too many people are still The ABC Global Alliance invites all interested participants dying of advanced breast cancer (ABC) too early who are registered to attend the ABC4 Conference to join Deach year. The burden of the disease is expected its first meeting which starts immediately after the ABC4 to increase dramatically in the coming years with the Conference and will be held across two half day sessions developing world hit hardest. at the following times: With the advances in science, technology and communi- - Part 1: Saturday, 4 November, from 15:00 to 18:00, and cation tools, it is imperative that the cancer community - Part 2: Sunday, 5 November, from 9:00 to 13:00 around the globe joins forces to raise awareness of the ABC4 registered participants are cordially invited to disease and lobby for better outcomes for people living express interest in attending by contacting ABCGlobalAl- with ABC. [email protected]. For further information, please visit The ABC Global Alliance, established by the European www.abcglobalalliance.org. School of Oncology, is a multi-stakeholder platform for all On behalf of everyone at the ABC Global Alliance, we look those interested in collaborating on common projects forward to welcoming you in Lisbon. relating to ABC. Launched at the World Cancer Congress in 2016, its goal is to improve and extend the lives of The ABC Global Alliance is an ESO initiative sponsored through unrestricted grants provided by AstaZeneca (Main Sponsor), women and men living with ABC in all countries wor- Novartis (Main Sponsor), Pfizer (Main Sponsor) and Lilly (Sponsor). ldwide and to fight for a cure.
Saturday, 4 November and Sunday, 5 November 2017
ABC4 will be followed by the first meeting of the ABC Global Alliance that will be held across two half day sessions at the following times:
- Part 1: Saturday, 4 November, from 15:00 to 18:00, and - Part 2: Sunday, 5 November, from 9:00 to 13:00
The detailed programme will be published in the final announcement.
ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 16 #ABClisbon Sponsored satellite symposia Thursday, 2 November 2017
9:00-10:30 Sponsored satellite symposium 1 - AstraZeneca Audit. 1 Illuminating a new pathway in breast cancer
- The guiding light – meeting the needs of the patient - Welcome and introduction - Highlighting a new target in breast cancer – DNA damage response - Shining the light on a new breast cancer paradigm - opportunity for questions - PARP inhibitors – a spark for change in breast cancer management - In the spotlight – the use of BRCA in clinical practice - opportunity for questions - Summary and close
Symposium faculty: Cristina Cruz, Institute of Oncology, Barcellona, Spain Pierfranco Conte, Istituto Oncologico Veneto, Padova, Italy Christian Jackisch, Sana Klinikum Offenbach, Offenbach, Germany Sibylle Loibl, German Breast Group, Neu-Isenburg, Frankfurt, Germany
11:00-12:30 Sponsored satellite symposium 2 - Novartis Audit. 1 Patient-centric treatment decisions in clinical practice: Harnessing the power of combination therapy
- Joining forces for efficacy: The current state of targeted therapy for HR+, HeR2– advanced breast cancer Chair: Luis Costa, PT - Diana Luftner, DE
- Patterns, combinations, and sequences: Case-based discussion on treatment decisions for HR+, HeR2 – Advanced Breast Cancer Case Presenter and Moderator: Diana Lüftner, DE Panelists: Luis Costa, PT - Guenther Steger, AT
- Q & A discussion Moderator: Guenther Steger, AT
- Forging future understandings Chair: Luis Costa, PT
Symposium faculty: Luis Costa, Hospital Santa Maria, Lisbon, Portugal Diana Lüftner, Humboldt University, Berlin, Germany Guenther Steger, Medical University of Vienna, Vienna, Austria
LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 17 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference
18:00-19:30 Sponsored satellite symposium 3 - Pfizer Audit. 1 A united vision for mBC: Changing the treatment paradigm with CDK4/6 inhibitors Chair: Michael Gnant, AT
- Welcome and introduction Michael Gnant, AT
- A united vision for HR+ HER2– mBC: The Global Decade Report Speaker to be announced
- Q&A Speaker to be announced
- Challenging current perceptions in HR+/HER2– mBC Sibylle Loibl, DE
- A glimpse into the therapy management of CDK4/6 inhibitors Johannes Ettl, DE
- Panel discussion and Q&A All faculty
- Closing remarks Michael Gnant, AT
Symposium faculty: Johannes Ettl , Technical University of Munich, Munich, Germany Michael Gnant , Medical University of Vienna, Vienna, Austria Sibylle Loibl , German Breast Group, Neu-Isenburg, Frankfurt, Germany
Friday, 3 November 2017
18:00-19:30 Sponsored satellite symposium 4 - Celgene Audit. 1 The evolving sequence of therapies, moving forward in mBC: All chemotherapies are not created equally Chair: Grazia Arpino, IT
- Welcome and objectives Grazia Arpino, IT
- Interactive patient case series: Improving how we manage patients with mBC Frederik Marme, DE - Marina Cazzaniga, IT - Eva Ciruelos, ES - Indolent mBC: Are we making optimal use of all our treatment options? - Rapidly progressive mBC: Identifying the correct treatment sequence in these challenging patients - Treating triple negative mBC: Clinical considerations for the use of Abraxane
ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 18 #ABClisbon
- Improving disease outcomes in patients with mBC: Choosing the right algorithm Panel and audience discussion of the patient case study series
- Summary and close Grazia Arpino, IT
Symposium faculty: Grazia Arpino, University of Naples Federico II, Italy marina Cazzaniga, San Gerardo Hospital, Monza, Italy eva Ciruelos, University Hospital 12 de Octubre, Madrid, Spain Frederik marme, Universität Heidelberg, Heidelberg, Germany
Sponsors (as of July 2017)
ESO wishes to express its appreciation for the following sponsors for having granted their participation and support to ABC4.
Travel grants, support to the Conference and to the patient advocacy activities
Participating organisations and companies
LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 19 Advanced Breast Cancer Fourth ESO-ESMO International Consensus Conference Registration Online registration is available at www.abc-lisbon.org
Registration grants participation in all sessions, a copy of the Programme and of the Abstract Book, coffee breaks, lunches, welcome cocktail as indicated in the programme. Early Late On-site (passed, 30 July 2017) (by 15 October 2017) (from 16 October 2017)
Registration fee EUR 450 Club ESO Members EUR 350 EUR 550 EUR 700 ESMO Members EUR 350 Cancellation Cancellation should be notified to ESO in writing. In case of cancellation without replacement, the fee minus EUR 100 for handling charges will be refunded within three months from notification, provided that the cancellation is received by ESO before 31 August. Replacements will be possible till 10 October. Badge The badge is the only official evidence of registration and should be worn at all times during the event. Loss of badge causes loss of registration. Nurses and patient advocates Nurses and representatives of cancer patient advocacy non-profit organisations are eligible for a discounted registration fee: EUR 250 passed (30 July 2017) EUR 300 by 15 October 2017 EUR 400 from 16 October 2017 and on-site. To register to the Conference, nurses and representatives of patient advocacy organisations should submit the following documents within the deadline: • Nurses: curriculum vitae with full contact details • Patient advocates: curriculum vitae or resume indicating the advocacy experience, role within the organisation and the full contact details of the patient advocate organisation. media registration The Conference welcomes representatives of print and electronic media. Registration is free of charge to journalists who are in possession of a valid, recognised press card. Freelance journalists must present a commissioning letter on headed paper from a recognised news organisation or publication. Representatives of advertising, marketing and public relations companies are not eligible for free media registration. A copy of the Press Card or of the commissioning letter should be sent together with the media registration form available at www.abc-lisbon.org. Group registration The online group registration may be processed online for groups of 5 or more individuals. The procedure and deadlines are published at www.abc-lisbon.org Registration to the first meeting of the ABC Global Alliance ABC4 registered participants are cordially invited to attend the meeting that will take place on Saturday 4 November, from 15:00 to 18:00 and on Sunday 5 November f rom 09:00 to 13:00 by contacting [email protected]. For further information about the ABC Global Alliance, please visit www.abcglobalalliance.org.
ABC4 • 2-4 NOVEMBER 2017 | LISBON, PORTUGAL 20 #ABClisbon Hotel accommodation Deadline for booking: 28 October 2017 Book online at www.congressospco.abreu.pt/ABC4-31793.aspx
iagens Abreu has been designated as the official accommodation service for ABC4 and offers discounted Vrates at selected hotels. In order to secure availability and the discounted rates, participants are kindly required to proceed with their bookings by 28 October 2017.
Rates are indicated in Euros (VAT included) and are meant per room, per night, including buffet breakfast. City Tax supplement of 1€ per person, per night stay, up to a maximum of 7€ per person to be paid to the hotel. Payment of the stay is required to confirm the booking.
Distance Public Single room Double room Hotel Category Km/time transportation euR euR
Pestana Palace 0,8/8’ (walking dist) 5-star 165 180
Jeronimos 8 2,5/15’ A 4-star 165 175
Vila Gale Opera 0,3/3’ (walking dist) 4-star 145 150
Tivoli Lisboa 5/20’ B 5-star 160 172
Tivoli Jardim 5/20’ B 4-star 149 159
Marques de Pombal 5/20’ B 4-star 102 114
Further hotel options are available on the online booking system.
Complete information on the hotels, hotels map and public transportation can be found here: http://bit.ly/2cRvqsM
Booking cancellation: Cancellations should be notified in writing to Helder Carvalho, Viagens Abreu. Until 2 August fully refunded less EUR 25 as administrative fees Until 15 September 50% will be refunded Until 15 October 25% will be refunded From 16 October no refund No-shows no refund
For further information please contact Helder Carvalho, Viagens Abreu SA, Linda-a-Velha, Portugal [email protected] - ph +351 21 415 6120 - fx +351 21 415 6383
LISBON, PORTUGAL | 2-4 NOVEMBER 2017 • ABC4 21
#ABClisbon Registration form
Please fill in this form in block capitals and send by the deadline to: european School of oncology - Piazza Indipendenza, 2 - 6500 Bellinzona - Switzerland Luis Carvalho - Tel: +41 91 820 09 58 - Fax: +41 91 820 09 53 - Email: [email protected] Laura Richetti - Tel: +41 91 820 09 51 - Fax: +41 91 820 09 53 - Email: [email protected] Participant’s details Dr. Prof. Mr. Mrs Family name First name Organisation Department Street Zip Code Town Country Phone Fax Mobile e-mail Date of birth Birth place (town and country) Profession Specialisation Main field VAT number (Compulsory for self-employed persons) Fiscal code (Italian residents only)
Are you an eSmo member? YES NO If YES: Membership ID: Expire date (DD/MM/YYYY):
If your invoice details are different to those above, please complete the following section: Invoice contact details Address e-mail Phone VAT number (Compulsory for companies or self-employed persons) Fiscal code (Italian residents only) Registration
Early (by 30 July 2017) Late (by 15 October 2017) On-site (from 16 October 2017)
Registration fee EUR 450
Club ESO Members EUR 350 EUR 550 EUR 700
ESMO Members EUR 350
Payment details The registration is processed when payment accompanies the form(credit card details or copy of bank transfer) Visa/Mastercard Card Number / / / Expiry date / CV2 code Holder’s name: and signature BANK TRANSFER with no cost to the beneficiary (please provide a copy of the bank transfer): Bank: Banca Popolare di Milano, Agenzia 24 - Milan, Italy Account holder: European School of Oncology Number: No. 16333 IBAN: IT96G0558401624 0000000 16333 BIC: BPMIITMMXXX Reference: "ABC4" + your name I authorise the European School of Oncology and any possible partner organisations in the event to use my personal data according to what is specified in Article 13 DLGS 196, available at www.eso.net or on request at fax number +39 02 8546 4545.
Signature Date
oNLINe ReGISTRATIoN AVAILABLe AT WWW.ABC-LISBoN.oRG Bridging the Gap
www.eso.net www.abc-lisbon.org
milan Bellinzona Via Turati, 29 Piazza Indipendenza, 2 20121 Milano - Italy 6500 Bellinzona - Switzerland Phone: +39 02 8546451 Phone: +41 91 8200950 Fax: +39 02 85464545 Fax: +41 91 8200953 [email protected] [email protected]