Electronic Supplementary Material (ESI) for New Journal of Chemistry. This journal is © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2019
Submitted to New Journal of Chemistry (Manuscript ID: NJ-ART-05-2019-002580)
Design, Synthesis, In silico docking studies and biological evaluation of novel quinoxaline-hydrazide hydrazone-1,2,3-triazole hybrids as α-glucosidase inhibitors, antioxidants
Settypalli Triloknadh,a Chunduri Venkata Rao*a, Maddineni Aruna Kumaria, Begari Nagarajua, Allagadda Rajasekhar,b Kotha Peddannab and Chippada Appa Raob
aDepartment of Chemistry, bDepartment of Biochemistry, Sri Venkateswara University, Tirupati- 517502, Andhra Pradesh, India.
*a Corresponding author: Prof. Chunduri Venkata Rao E-Mail: [email protected], Tel: +91 9849605140, Fax: +918772289555. ORCID: 0000-0001-8008-3763
First author: Dr. Settypalli Triloknadh ORCID: 0000-0001-8106-1646
CONTENTS Pg. No 1H-NMR Spectra of synthesized compounds ------1-21 13C-NMR Spectra of synthesized compounds ------22 - 35 MASS Spectra of synthesized compounds------36-53
Supporting Information, Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 1
1H-NMR spectrum of compound 2
Supporting Information, 1 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 2a
1H-NMR spectrum of compound 3
Supporting Information, 2 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 3a
1H-NMR spectrum of compound 7
Supporting Information, 3 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 8a
1H-NMR spectrum of compound 8c
Supporting Information, 4 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 8d
1H-NMR spectrum of compound 8f
Supporting Information, 5 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 8g
1H-NMR spectrum of compound 8h
Supporting Information, 6 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 8j
1H-NMR spectrum of compound 9
Supporting Information, 7 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 9a
1H-NMR spectrum of compound 10
Supporting Information, 8 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 11
1H-NMR spectrum of compound 12
Supporting Information, 9 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 13d
1H-NMR spectrum of compound 13g
Supporting Information, 10 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 13i
1H-NMR spectrum of compound 13j
Supporting Information, 11 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 14a
1H-NMR spectrum of compound 14b
Supporting Information, 12 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 14c
1H-NMR spectrum of compound 14d
Supporting Information, 13 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 14e
1H-NMR spectrum of compound 14f
Supporting Information, 14 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 14g
1H-NMR spectrum of compound 14h
Supporting Information, 15 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 14i
1H-NMR spectrum of compound 14j
Supporting Information, 16 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 15a
1H-NMR spectrum of compound 15b
Supporting Information, 17 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 15c
1H-NMR spectrum of compound 15d
Supporting Information, 18 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 15e
1H-NMR spectrum of compound 16a
Supporting Information, 19 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 16b
1H-NMR spectrum of compound 16c
Supporting Information, 20 Department of Chemistry, Sri Venkateswara University –Tirupati
1H-NMR spectrum of compound 16d
1H-NMR spectrum of compound 16e
Supporting Information, 21 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 1
13C-NMR spectrum of compound 2
Supporting Information, 22 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 2a
13C-NMR spectrum of compound 3
Supporting Information, 23 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 3a
13C-NMR spectrum of compound 11
Supporting Information, 24 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 12
13C-NMR spectrum of compound 13d
Supporting Information, 25 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 13i
13C-NMR spectrum of compound 14a
Supporting Information, 26 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 14b
13C-NMR spectrum of compound 14c
Supporting Information, 27 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 14d
13C-NMR spectrum of compound 14e
Supporting Information, 28 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 14f
13C-NMR spectrum of compound 14g
Supporting Information, 29 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 14h
13C-NMR spectrum of compound 14i
Supporting Information, 30 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 14j
13C-NMR spectrum of compound 15b
Supporting Information, 31 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 15c
13C-NMR spectrum of compound 15d
Supporting Information, 32 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 15e
13C-NMR spectrum of compound 16a
Supporting Information, 33 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 16b
13C-NMR spectrum of compound 16c
Supporting Information, 34 Department of Chemistry, Sri Venkateswara University –Tirupati
13C-NMR spectrum of compound 16d
13C-NMR spectrum of compound 16e
Supporting Information, 35 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 1
Mass spectrum of compound 2
Supporting Information, 36 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 2a
Mass spectrum of compound 3
Supporting Information, 37 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 3a
Mass spectrum of compound 13a
Supporting Information, 38 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 13e
Mass spectrum of compound 13g
Supporting Information, 39 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 13i
Mass spectrum of compound 13j
Supporting Information, 40 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 14a
Mass spectrum of compound 14c
Supporting Information, 41 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 14b
Supporting Information, 42 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 14b
Supporting Information, 43 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 14d
Mass spectrum of compound 14e
Supporting Information, 44 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 14f
Mass spectrum of compound 14g
Supporting Information, 45 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 14h
Mass spectrum of compound 14i
Supporting Information, 46 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 15a
Supporting Information, 47 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 15a
Supporting Information, 48 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 14j
Mass spectrum of compound 15b
Supporting Information, 49 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 15c
Mass spectrum of compound 15d
Supporting Information, 50 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 15e
Mass spectrum of compound 16a
Supporting Information, 51 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 16b
Mass spectrum of compound 16c
Supporting Information, 52 Department of Chemistry, Sri Venkateswara University –Tirupati
Mass spectrum of compound 16d
Mass spectrum of compound 16e
Supporting Information, 53 Department of Chemistry, Sri Venkateswara University –Tirupati