National Institute of Pharmaceutical Education and Research, Ahmedabad

राय औषधीय शा एवं अनुसंधान संथान (नाईपर), अहमदाबाद

PLACEMENT BROCHURE 2018-2020

TABLE OF CONTENTS

Vision & Mission 2

About the Institute 3

Message from Director’s Desk 4

Message from Registrar’s Desk 5

Why us? 6

Instruments 7

Student’s Resume 10

Department of Biotechnology 10 Department of Medical Devices 16 Department of Medicinal Chemistry 22 Department of Natural Products 31 Department of Pharmaceutical Analysis 37 Department of Pharmacology & Toxicology 46 Department of Pharmaceutics 55

Placement Committee 65

Student’s Placement Committee 65

Recruiters 67

Contact us 68

1

VISION

“To be a Nationally and Internationally recognized premier Centre of Excellence in Teaching, Research and Entrepreneurial Training in Pharmaceutical Science and Biomedical Technology” MISSION

 To ensure that departmental and administrative associates are provided with necessary resources to excel in learning, research, teaching and administration  To establish National Centre of Medical Devices (NCMD) for contributing for medical technology education through collaborative programs of mutual interest  To evolve medical technology clusters with common facilities for creating an ecosystem for the benefit of SME’s focusing on medical technology  Development of human resources by skill up-gradation of students through specialized courses and training  To encourage students for innovative translational research through interdisciplinary research team  To promote national and international collaboration with Pharmaceutical Industries, Medical Centers and Universities  To facilitate international student and faculty exchange programmes to enhance the diversity on the campus  To organize International and National conferences and structured workshops for the benefit of students and professional

2

ABOUT THE INSTITUTE

India is amongst the top 10 countries in the world considering volume and value of Pharmaceutical products. Enthusiastic and entrepreneurial efforts have turned Gujarat into the hub of pharmaceutical manufacturing, research & development activities. The innovative and translational approach of the Indian scientists resulted paradigm shift from the industrial age to knowledge enriched economy. Pharmaceutical education has played a crucial role in human resource development, catalyzing the growth of life sciences and healthcare industry.

The visionary augmentation of the Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of has led to the establishment of six new NIPERs in 2007 and one of them is NIPER Ahmedabad. Since August 2016, NIPER Ahmedabad is functioning from its own campus (transient building) on 60-acre landsite at Gandhinagar. The institute offers MS and Ph.D. programs in Pharmaceutics, Pharmaceutical Analysis, Pharmacology & Toxicology, Biotechnology, Natural Products, Medicinal Chemistry and Medical Devices. NIPER Ahmedabad would like to create a Centre for Medical Devices (CMD) in the campus to cater as well as nurture the need of booming medical device industries with-in and outside India.

The interdisciplinary courses and cultural diversity at NIPER-Ahmedabad sparks the spirit of innovative research and all-round development of its students. The location of the institute ensures a symbiotic association with Pharmaceutical Industries, Medical centers and technological universities. In year 2019, it has achieved all India Rank #1 in TLR (teaching, learning and research) and in OI (outreach and inclusivity) with overall 9th best pharmaceutical college as per NIRF ranking 2019 of MHRD. NIPER Ahmedabad aspires to serve as a good launching platform to revamp the pharmaceutical education and research, and to initiate the new era of pharmaceutical and biomedical sciences.

3

FROM THE DIRECTOR’S DESK

Dear Recruiters, Heartfelt Greetings! It is a matter of honor and privilege to welcome the World Class Industries to recruit highly competitive and best brains of the pharmaceutical sector, trained and nourished under the excellent faculties of NIPER Ahmedabad. NIPER Ahmedabad is on a fascinating path of growth and development in Pharmaceutical and Healthcare arena. As you are aware, it has already established itself as a premier research institute known for outstanding cutting-edge research carried out by budding pharmaceutical scientist in the state-of-the-art laboratories. The distinction in teaching and research has resulted from the careful choice of faculty members in which NIPER Ahmedabad has not made any compromise. It has gone to outreach and fetch scientists having academic as well as industrial experience to enrich its faculty strength and quality. As a result, students are not only molded and trained for research, but also groomed to satisfy the requirements of the industry by inculcating impeccable competency and skills. They are exposed to various sophisticated instruments like NMR, Small Animal Imaging System, Confocal Microscope, LC-MS, and HPLC, etc. NIPER Ahmedabad gives them an opportunity to train their hands to become capable and achieve excellence. I am glad to share that we have secured ALL INDIA RANK #1 in TLR (Teaching, Learning and Research) and OI (Outreach and Inclusivity) with overall 9th best pharmaceutical college as per NIRF ranking 2019 of MHRD. Since the inception, we have an excellent record of more than 80% students placed in the best pharmaceutical industries. This year, I am looking forward to see the students of NIPER Ahmedabad getting recruited and serving the dynamic healthcare system.

Prof. Kiran Kalia Director, NIPER Ahmedabad

4

FROM THE REGISTRAR’S DESK

Best wishes from NIPER Ahmedabad Administration!

I am happy to highlight discerning qualities imbibed by the students of NIPER-A on their journey towards nurturing a bright career in pharmaceutical industry and research. The environment of the institute aims to instill self-discipline, participative behavior and self-regulation, replicating the professional work culture of any esteemed corporate organization.

The students have observed the best practices adopted by the institute which has inculcated the traits to meet the requisite culture of pharmaceutical industries. The adherence to the institute’s rules and regulations is the testimony of the student’s maturity and readiness for the decisive career in the industry.

I am confident that such exceptionally groomed students will not only fit into the corporate environment, but also make a meaningful contribution to the organization.

Mr. Kunal Maheshwari I/c Registrar, NIPER Ahmedabad

5

WHY US? Rigorous Selection Criteria:  Qualified GPAT  Passed B. Pharm with First Class  NIPER JEE Exam

NIPER Ahmedabad:  Institute is one of the top 10 pharmaceutical college as per NIRF ranking 2019 of MHRD  Institute is having India Rank #1 in TLR (teaching, learning and research) and in OI (outreach and inclusivity)  Students are trained and nourished under the excellent faculties having industrial experience  Students have hands on exposure to various sophisticated instruments with online documentation on electronic lab notebook (ELN) and are groomed to satisfy the requirements of the industry by inculcating impeccable competency and skills  Interdisciplinary courses and cultural diversity at NIPER-Ahmedabad sparks the spirit of innovative research and all-round development of its students  As per MHRD, NIPER Ahmedabad constituted the “Institution’s Innovation Council (IIC)” which inculcates the entrepreneurship skills in students

 Students are rigorously trained for drug development market

6

INSTRUMENTS

Q-TOF-LCMS FTIR ATR

Gel Permeation Gas Chromatography HPLC Chromatography

Confocal Microscope: Leica Flash chromatography Semi-preparative HPLC TCS SP8

7

Thermogravimetric Porosity meter Ultracentrifuge Analyzer

Differential Scanning Multimode Reader UV Plate Reader Calorimeter

Nanodrop Real-Time PCR Fumehood

Deep Freezer (-80°C) Western Blot Unit Biosafety Cabinet (Class II)

8

NMR 500MHz Bio Rad S3eTM Cell Sorter IVIS

Scanning electron Rotary Evaporator Inverted Microscope microscope

Gel Doc System Cryo can Parallel Synthesizer

9

Department

Of Biotechnology

Departmental Expertise:  Proteomic and genomic Biomarkers for Diabetes and its microvascular complications  Role of miRNA in epigenetics and pathogenesis of diabetic nephropathy  Transcriptome analysis of Oral Squamous Cell Carcinomas patients from Gujarat, India  Developing bioengineered three-dimensional disease model  Separation and purification of therapeutic cell-types e.g. stem cells from intervertebral disc  Repair and regeneration of musculoskeletal and nerve tissues  Pharmacogenetics studies and population-based genome analyses like genomic alteration in cancer and diabetes  Cancer research to overcome chemoresistance and prevention of relapse by Cancer Stem Cells (CSCs) re-differentiation and co-lethality approach  Comparative simulation study of human and rat Aβ aggregation for the development of the potential therapeutic application for the Alzheimer  Structure-function relationship of the boronic acid-based ligand with tumor M2PK (M2 pyruvate kinase) protein using structural bioinformatics and molecular dynamics approaches  In-silico drug design: Hit to lead optimization  Evaluating the anti-cancer potential of compound/drug using various assays: cell viability, colony formation assay, soft agar assay, migration, invasion assay using Matrigel, cell adhesion, cancer stem cell isolation and characterization, tumor sphere

assay.  Generation of induced Pluripotent Stem Cells (iPSCs) using non-viral methods and its re-differentiation 10

BHAVINKUMAR ARJUNBHAI GAYAKVAD Address: 118, Jalaram nivas Malga , Po:- Garkhdi Ta:- Subir-Dang, Gujarat Contact no.: +91 94 088 000 53 E-mail ID: [email protected] LinkedIn Profile: https://linkedin.com/in/bhavin-gayakvad-63711713a

Education: Achievements:  Qualified NIPER JEE  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical Education 2018 & GPAT 2018 and Research (NIPER), Ahmedabad with 7.93 CGPA till 2nd semester  2nd prize in poster  2014-18: Bachelor of Pharmacy from Smt. B.N.B Swaminarayan pharmacy college Salvav presentation at national level conference. vapi NH -8, affiliated by Gujarat Technological University, Gujarat with 8.16 CGPA Skills: Dissertation:  Decision Making  Title: Self-assembly of elastin based peptides for enhancement of extracellular matrix  Quick Learner production; a computational and experimental approaches.  Description: We are trying to develop the natural scaffold system by means of self-assembly Language Known: of some peptides in fibrils form. Our target is to use cellular components to fabricate the scaffold  English, Gujarati, Hindi, which have additional advantages than synthetic scaffolds. Computational approaches like MD Marathi simulations will be helpful to generate the experimental conditions and understand the possible mechanism of self-assembly. Computational data will be used in the fabrication of scaffold experimentally, after fabrication we will check the production of ECM by In-vitro techniques as a reference of developing natural scaffold by cells.

THARALLA ANIL KUMAR Address: H no:1-21/4, Thatipaly (vill), Jagtial (Mandal), Jagtial (Dist.), Telangana, India. 505453 Contact no.: +919492407431 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/anil-kumar-tharalla-430917187/

Education: Achievements:  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical Education  Qualified NIPER JEE and Research (NIPER), Ahmedabad with 5.83 CGPA till 2nd semester 2018 & GPAT 2018

 2014-18: Bachelor of Pharmacy from Sri Indu Institute of pharmacy, JNTU Hyderabad, Skills: Telangana with 65%  Self-discipline Dissertation:  Able to work effectively  Title: To evaluate the role of styryl-quinazolinone family of compounds on oral cancer and the efficiently Acquired chemoresistance  Handling with instruments  Description: OSCC frequently arises in the mucosa of oral cavity and oropharynx, and is like PCR, western blot, increasingly becoming a national problem. There is not much improvements in the overall multimode reader survival rate of OSCC patients. The purpose of the present study is to investigate the effect(s)  Cell culture of Styryl-quinazolinone family of compounds on various cellular functions and signaling events linked to OSCC, in particular IL-8 overexpression, as has been observed in a recent study Language Known: from Biotechnology Department, NIPER-A. As chemoresistance is a major hurdle in oral  English, Telugu, Hindi cancer treatment Our study to determine if the selected Styryl-quinazolinone derivatives possess the potential to sensitize OSCC cells towards cisplatin treatment.

11 RAISA PARVEEN QADEER AHMED SHAIKH Address: H.No. 8-14-279, near Rehan Apartment, Kareem Colony, Roshan Gate, Aurangabad-431001 Contact no.: +919561490106 E-mail ID: [email protected] LinkedIn Profile: http://www.linkedin.com/in/raisa-parveen-shaikh-094186186

Education: Achievements:  Qualified NIPER JEE 2018  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical & GPAT 2018 nd Education and Research (NIPER), Ahmedabad with 8.1 CGPA till 2 semester  Qualified MT-CET-2014  2014-18: Bachelor of Pharmacy from Government College of Pharmacy, Aurangabad under with AIR- 733 Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, with 65.85%. Skills: Dissertation:  Cell culture  Title: Evaluating the effect(s) of α-mangostin treatment on oral cancer and understanding  Drug testing assay the underlying mechanism(s).  Data processing skill  Description:  Adaptable and positive Evaluation of the anticancer effect of natural compound α-mangostin (Xanthone derivative) towards work isolated from pericarp of Mangosteen fruits on oral cancer cell lines and normal oral epithelial cell line with respect to cytotoxicity, cell proliferation, metastasis, cell adhesion and Epithelial Language Known: to Mesenchymal transition (EMT) to find its mechanism involved for anticancer activity.  English, Hindi, Marathi, Urdu

VEERA NAGA SAI MANIKANTA KELLA Address: S/O Rambabu,11-175, C-2, Gandhi statue street, Eluru road, Gudivada, Krishna (Dist) Andhra Pradesh, India 521301 Contact no.: +918328679163 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/mani-manu-94a721151

Work Experience: In GVK Biosciences as Junior Research Analyst for 9 months. Achievements: Education:  Got appreciation letter from  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical Union human resource Education and Research (NIPER), Ahmedabad with 7.16 CGPA up to 2nd semester development minister Kapil Sibal for scoring 8.6 CGPA  2014-18: Bachelor of Pharmacy from V.V. Institute of pharmacy in year 2017 from JNTUK in secondary school with an aggregate of 73.88 % examination Dissertation:  Employee of the Month,  Title: To study the effect of Aryl -quinazolinones on oral cancer August 2018  Description: The recent advancement in treatment modalities, the five-year survival of cancer patients has not improved. Hence, there is need to develop alternate strategies and Skills: identify new targets and/or compounds. The synthetic derivatives of an Aryl-quinazolinone  Ability to manage time and have been reported to be chemo preventive and anticancer activities inducing apoptosis, prioritize tasks inhibiting cell migration, invasion & proliferation in different cancer types. In the present  Problem-solving skills, Critical study, we aim to evaluate the effect of synthetic derivatives in oral cancer using various cell thinking and analytical skills lines and will also target to understand the mechanism(s) underlying the observed effect(s).  Excellent communication and In a recent transcriptome analysis study in Biotechnology Department,significant up interpersonal skills regulation of Interlukin-8(IL-8) was found in oral cancer patients, hence, we will extend our study to determine if Aryl-quinazolinone modulates IL-8 to mediate their effects in oral cancer Language Known: and if any structural modifications are needed to potentiate towards their activity towards IL-  English, Hindi, Telugu 8.

12 RUTUJA MARUTI SATVASE Address: B/206/34, Nandini CHS, Shivai , Thane (west), Pincode-400606 Contact no.: +918879636578 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/rutuja-satvase-9305a516

Education: Achievements:  Qualified NIPER JEE 2018  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical and GPAT 2018 nd Education and Research (NIPER), Ahmedabad with 7.96 CGPA till 2 semester  Consolation prize in poster  2014-18: Bachelor of Pharmacy from Oriental college of Pharmacy, University of , competition Maharashtra with 7.53 CGPA Skills: Dissertation:  Techniques-Agarose gel  Title: To study the effect of α-mangostin treatment on chemoresistance and stemness of electrophoresis, western oral cancer cells blotting, RNA isolation, PCR,  Description: Cancer stem cells (CSCs) are the subpopulation of cells which are present in  Instruments-Gel doc, Flow the tumor, having the capability of self-renewal, differentiation and tumorigenecity. These cytometry, Nanodrop, CSCs are responsible for tumor recurrence in majority of cancer patients, as they are highly Transblot. chemoresistant due to the presence of various attributes like, enhanced ABC transporter  Hands on experience of cell expression, enhanced ALDH activity, dysregulation of signaling pathways, etc. In our study, culture and cell based we aim to demonstrate that, α-mangostin, a prenylated xanthone, obtained from the assays. pericarps of Garcinia mangostana Linn, may possess the capacity to sensitize cisplatin

resistant oral cancer cells and thereby also affect the oral cancer stem-cell characteristics. Language Known:  English, Hindi, Marathi

NAZMINA VHORA Address: 5/B, Hina Park, Vhora Society, Mahemadabad, 387130. Contact no.: +91 7046817377, 8490911331 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/nazmina-vhora_984062a7.

Education: Achievements:  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical Education  Qualified NIPER JEE 2018 & and Research (NIPER), Ahmedabad with 9.3 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from A.R.Collage of Pharmacy, Gujarat technological Skills: university, Gujarat with 8.43 CGPA  Quick learner Dissertation:  Positive attitude towards the work  Title: Understanding of molecular mechanism of the selected anti-diabetic natural products by  Strong interpersonal and in-silico and in-vitro studies leadership skill

 Description: In this project we are working in the area of diabetes. On the basis of epidemiology Language Known: & prevalence, we have chosen type-2 diabetes mellitus as a target. This is an interdisciplinary  English, Hindi, Gujarati project, in which we are working on some anti-diabetic small molecules from natural sources. We hypothesized that these molecules are having GLP-1 receptor agonist activity. The major reason behind the selection GLP-1 receptor as a target is GLP-1R induces glucose dependent insulin secretion, so it will avoid the major side effect of other anti-diabetic agent that is hypoglycemia. These molecules are screened from 251 molecules from the dictionary of natural products on the basis of docking score, availability, yield and structural diversity. In-vitro assays will be performed to check the anti-diabetic activity of these molecules and a computational approach that is molecular dynamics and simulation study to establish their mechanism of action.

13 SAMDISHA VIRENDRA DUBEY Address: 2/8 KDT compund, Datta mandir road, Bhandup- west, Mumbai- 400 078, Maharashtra, India. Contact no.: +91 8454090383 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/samdisha-dubey-063510141

Education: Achievements:  Qualified NIPER JEE 2018  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical Education and & GPAT 2018 nd Research (NIPER), Ahmedabad with 9.4 CGPA till 2 semester  Awarded as Best Student in  2014-18: Bachelor of Pharmacy from Saraswati Vidya Bhavan’s College of Pharmacy (SVBCP), 2018 by SVBCP, Mumbai Mumbai University, Maharashtra with 7.84 CGPA University. Dissertation:  Title: To Study the Role of Interleukin-8 (IL-8) And Its Regulation in Oral Cancer Skills:   Description: Oral cancer, defined as cancers of lip, tongue and mouth is a serious and growing Cell culture, protein problem in many parts of the globe and is the sixth most common cancer in the world. Most common characterization, bioassays.  alterations in OSCC include functional inactivation/deletion of tumor suppressors, activation of miRNA identification using oncogenes, and deregulation of growth factor signaling and their effectors. IL-8 is a proinflammatory various tools like CXC chemokine associated with the promotion of neutrophil chemotaxis and degranulation by TARGETSCAN,RNA22, activating two cell-surface, G- protein-coupled receptors (CXCR1 and CXCR2). Increased miRNet etc. expression of IL-8 and/or its receptors has been characterized in cancer cells, endothelial cells,  Excellent communication and organizational skills. infiltrating neutrophils, and tumor-associated macrophages, suggesting that IL-8 may function as a significant regulatory factor within the tumor microenvironment. Therefore, inhibiting the effects of Language Known: IL-8 signaling may be a significant therapeutic intervention in targeting the tumor microenvironment.  In this study, we try to understand the role of IL-8 in oral cancer and mechanism of its regulation by English, Hindi, Marathi majorly focusing on the miRNAs that may be involved in mediating IL-8 deregulation in cancer.

SHAMBHAVI SUDAM ANDHALE Address: A/P. Karjule Harya, Tal.Parner, Dist.Ahmednagar, Pin code 414304 Contact no.: +919923826748 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/shambhavi-andhale-89a1ba193

Education: Achievements:  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical Education and  Qualified NIPER JEE 2018 Research (NIPER), Ahmedabad with 7.73 CGPA till 2nd semester & GPAT 2018

 2014-18: Bachelor of Pharmacy from Sitabai Thite College of Pharmacy, Shirur. Savitribai Phule Pune University, Maharashtra with 69.43% Skills:  Cell culture, PCR, Protein Dissertation: Characterization, RNA  Title: Cryogel Bioreactor for Therapeutic Exosome Production. isolation, Flow cytometry  Description: Exosomes are nanosized membrane vesicles released by various cells, which  Gel Doc, Nanodrop contains proteins, microRNA, mRNA and they provide a means of intercellular communication. The  FTIR/ATR exponential interest in exosomes increases due to their important roles in health and disease and  MS office to their potential clinical application in therapy and diagnosis. Conventional methods have several limitations which can be overcome by the novel cell native environment mimicking perfusion based Language Known: three dimensional approaches. In this study, we propose to increase the exosome production from  English, Hindi, Marathi Mesenchymal stem cells using covalent collagen coated supermicropores cryogel based three- dimensional matrix with the help of dynamic bioreactor system.

14 SONALI RAJESH GADGE Address: B6 Devdatta society, Subhash road , Vishnu nagar, Dombivali West 421202 Contact no.: +918286037933 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/sonali-gadge-a64036132

Education: Achievements:  Qualified NIPER JEE 2018 and GPAT  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical Education and 2018 nd Research (NIPER), Ahmedabad with 8.45 CGPA till 2 semester  1st prize in YPIPA 2018-Novel Device  2014-18: Bachelor of Pharmacy from Saraswathi Vidya Bhavan College of Pharmacy, Mumbai for Navel Drug Delivery System University, Maharashtra with 7.9 CGPA  Presentation on ‘Novel device for Dissertation: navel route DDS at Sun Pharma,  Title: Development of breast cancer organoids in mini-hydrogels. Mumbai.  Description: Organoids are artificially grown 3D cell cultures that preserve numerous features Skills: and function of an organ. Earlier the studies were carried out on 2D cell cultures, mammospheres  Team management, Communication, and patient derived xenografts. But, due to lack of microenvironment, time and loss of public speaking heterogeneity these models did not mimic the actual microenvironment of the cancer. So the  Cell culture, organoid development, purpose of the work is to design and optimize 3D matrix made up of low molecular weight / high SDS-PAGE, western blotting molecular weight hyaluronic acid and collagen for development of organoids from breast cancer Language Known: cell line. One of the major applications of the organoid is testing and screening of drugs, to elucidate pathways involved in tumorigenesis and metastasis, etc.  English, Hindi, Marathi

DARSHAN CONTRACTOR Address: 41, Sarvoday society, Nizampura, Vadodara, Gujarat, India Contact no.: +919924669916 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/darshan-contractor-91854610a

Education: Achievements:  2018-20: M. S. (Pharm.) in Biotechnology from National Institute of Pharmaceutical Education and  Qualified NIPER JEE 2018 Research (NIPER), Ahmedabad, Gujarat with 7.94 CGPA till 2nd semester and GPAT 2018  2014-18: Bachelor of Pharmacy from Ramanbhai Patel College of Pharmacy, Charotar University of  Awarded Gold Medal from Science and Technology, Gujarat with 9.60 CGPA CHARUSAT Uni., for  2016-2018: Certificate Programme in Packaging Technology (CPPT) from Ramanbhai Patel College of securing University 1st Rank Pharmacy, Charotar University of Science and Technology with 8.50 CGPA in BPharm 2018 Dissertation: Skills:  Title: Structural and Functional Evaluation of Indole based Anti-cancer compounds targeting Histone  2-D Gel Apparatus Deacetylase(s).  Lyophilizer, Multiple plate reader  Description: The catalytic activity of the HDAC enzymes is directly related to the pathogenesis of cancer  Bioinformatics analysis- and several other diseases where hyperacetylation ultimately causes cell cycle arrest and apoptosis. So, molecular modelling (homology HDAC inhibition leads to a hyperacetylated state of the histones, initiating the transcriptional activation of modelling, structural alignment, suppressed genes. Currently, certain existing HDAC inhibitors have been shown to have the potential to etc) treat several types of cancers, but not with effective efficacy and selectivity, hence, available HDAC  inhibitors are not very effective as anticancer agents. Thus, the objective is to systematically analyze the Efficient in working in Team as 3D structures of all the isoforms of HDACs by employing the various tools of structural bioinformatics and well as Individually molecular modelling such as structural based sequence alignments, phylogenetic tree construction and homology modelling, to target 11Å deep active site and 14Å wide cavity of the HDACs, followed by Language Known: designing and optimizing HDAC inhibitors and validate them using in-vitro studies.  English, Hindi, Gujarati, Sanskrit

15 Department

Of Medical

Devices

Departmental Expertise:

 Design and development Microdevices for Biomedical Applications . Design and development of Microdevices drug delivery applications . Blood micro sampling devices for diagnostics and pharmaceutical application . Passive micropumps for paper microfluidics . Microdevices for gas/solute exchange applications . Devices for passive cooling of biomolecules (Proteins/cells) . Microdevices for cell and tissue culture applications like organoid development . Cell and exosomes separation

 Nanomaterial synthesis and characterization . Synthesis, characterization and application of versatile nanostructured materials (Quantum dots, Layered Nanoparticles, Polymeric Nanoparticles and Nanofibers) . Alternative strategies for Cancer Theranostic like Magnetic Hyperthermia and Photodynamic Therapy

 Polymer/composites Synthesis and characterization . Synthesis, characterization and application of polymer materials (PLLA, PolyHEMA) . Synthesis characterization and application of Bone cement (PMMA)

 Design and fabrication of Scaffolds for tissue engineering . Scaffolds for Intervertebral disc, spinal cord, bone, cartilage and ocular diseases . Smart biomaterials for articular surfaces and musculoskeletal tissue regeneration and care . Engineered approaches such as electrical and mechanical stimulations for regenerative medicine 16 BHAVANI JAGU Address: 1-3/13-7,Gupta centre,Vidhyadharapuram,Vijayawada,Krishna, Andhrapradesh, 520012. Contact no.: +919638643194 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/bhavani-jagu-604bb917a

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.00 CGPA till 2nd semester 2018 & GPAT 2018

 2014-18: Bachelor of Pharmacy from KVSR Siddhartha college of pharmaceutical sciences, Skills: Krishna university, Andhra Pradesh with 8.37 CGPA.  Technical skills like Dissertation: Electrospinning, UTM, DIC,  Title: Fabrication and characterization of multidimensional aligned collagen hydrogels UV, DSC.   Description: MS-Office, Chem sketch, Low back pain is the major health problem in the world due Intervertebral disc degeneration Autodesk and herniation. Currently Spinal fusion, total disc replacement, suture repair are the  Typing and Decision making approaches to treat low back pain. Tissue engineering is one of the approaches to repair and  Communication through Social media regenerate the Annular fibrosis tissue. Language Known:  English, Telugu, Hindi

ROHIT BABAN PARKALE Address: Plot No./E/22, Bhushan Nagar, Near Telephone Office, Ahmednagar, Maharashtra 414005. Contact no.: 9623482376 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/rohit-parkale-b87bb1167

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.53 CGPA till 2nd semester 2018 & GPAT 2018.  2014-18: Bachelor of Pharmacy from Government college of pharmacy Amravati, From Sant Skills: Gadage Baba University Amravati, Maharashtra with 6.86 CGPA  Handling of Electrospinning Dissertation: assembly,3D printer,  Title: Development of smart 3D printed bone cast to assist healing of fracture/dislocation and Universal testing machine, reduce postoperative infections. Zeta-sizer. Analytical  Description: we propose to address the problem associated with currently available instrument UV-Visible orthopedic cast through the development of 3D printed shell from the 2D images of a limb and spectroscopy, FTIR, DSC then integrating with a drug loaded, antibacterial nanofibrous membrane that will allow skin  Autodesk, Chembiodraw, breathability, overcome dryness, itching and any bacterial infection. This cast can act as a Origin, MS-office. drug delivery scaffold to supports a bone healing process and prevent postoperative infections.  Project Management. Language Known:  English, Marathi, Hindi

17 THOTA SIVA Address: House No: 2-83, Ramalayam veedhi, Veerabhadrapuram (Village), Yerragondapalem (Mandal), Prakasam (Dist), Andhra Pradesh (state), Pin code:523327. Contact no.: +918096352813 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/thota-siva-8b61893a

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.7 CGPA till 2nd semester 2018 and GPAT 2018 and  2014-18: Bachelor of Pharmacy from Dr. Samuel George Institute of Pharmaceutical 2017 Sciences, Acharya Nagarjuna University, Andhra Pradesh with 8.75 CGPA  3rd prize National Level Talent Hunt 2017 (Pharma Dissertation: Quiz)  Title: Drug loaded cobalt-zinc ferrite nanoparticles with self-regulated hyperthermia for Skills: targeted cancer therapy  Handling experience with  Description: Cancer is the major issue across the world. Currently available treatments for Magnetometer, 3D printer, cancer are chemotherapy, surgery, radiotherapy not that much effective treatment, so there is Electrospinning, UTM, DSC, a need for advanced combination therapy to treat cancer. Nanoparticles are applied in many Zeta-sizer, UV, FT-IR biomedical applications for their nano-range size and their inimitable properties (magnetic,  Autodesk, MS office, Chem optical and electronic). Magnetic nanoparticles show magnetization when external magnetic bio-draw field is applied it generates heat by hysteresis and relaxational losses, generation of heat (Hyperthermia) used in cancer cell lysis. This magnetic material surface modification with Language Known: polymer act as shell material, and then drug loaded into the shell, conjugate with ligand for  English, Telugu, Hindi targeted delivery.

KHARCHE SHUBHAM VILAS Address: At post-Shelgaon bazar, Dist-Buldhana,Maharastra, Pin code: 443102 Contact no.: +918605269866 E-mail ID: [email protected] LinkedIn Profile: http://www.linkedin.com/in/shubham-kharche-b87099161

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 8.53 CGPA till 2nd semester 2018 & Qualified GPAT  2014-18: Bachelor of Pharmacy from Government College of Pharmacy, Sant Gadge Baba 2018

Amravati University, Maharashtra with 7.15 CGPA Skills: Dissertation:  Technical Skills- Handling  Title: Pilot Scale Method Development for Production of Medical Grade Poly (L-lactic acid) experience in DSC, TGA,  Description: Poly-l-lactide (PLLA) is one of the most attractive polymer use in biomedical Electrospinning, UTM, GPC, applications. PLLA exhibit various pleasing properties include, bio absorbability, UV, FT-IR, 3D printing. biocompatibility and biodegradability. There are two choices for synthesis of PLLA either  polycondensation and Ring opening polymerization. The best method for the synthesis of high Language Known: molecular weight polymer is Ring opening polymerization. The problem about PLLA is easy  English, Marathi, Hindi unavailability and high cost. This polymer is usually import from other countries. So, the aim of the work is to develop method for synthesis of PLLA by optimizing various critical reaction parameters using QbD approach. This method will produce PLLA with high reproducibility, product yield, molecular weight and in economical way. The synthesized product will be characterized by various sophisticated analytical techniques such as, Differential Scanning calorimetry (DSC), FT-IR, Gel Permeation Chromatography (GPC), MALDI-TOF, etc. 

18 M.KEERTHANA Address: 29/14, Sadhu street, krishnapuram, Ambur, Vellore district, Tamilnadu - 635802 Contact no.: +919894389794 E-mail ID: [email protected] LinkedIN: https://www.linkedin.com/in/keerthana-mohan-547348175

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 8.56 CGPA till 2nd semester 2018 & GPAT 2018  2014-18: Bachelor of Pharmacy from College of Pharmacy, Madras Medical College (MMC),  3rd prize in All India Tamilnadu Dr. MGR Medical University, Tamilnadu with 77.85 % pharmacy quiz 2017

Dissertation: Skills:  Title: Electrochemical biosensor for early detection of Poly Cystic Ovarian Syndrome  Handling experience in  Description: Poly Cystic Ovarian Syndrome (PCOS) is a metabolic and endocrine disorder. Potensiostat- Galvanostat, 6 to 10 % of reproductive aged women affected worldwide. As the symptoms and signs of electrospinning, UV, FTIR, PCOS mimic other endocrine diseases, diagnosis starts with the exclusion test to rule out DSC, zeta-sizer, 3D printer. these diseases. As the Hormonal test and ultrasound imaging is performed at particular day  Autodesk fusion 360, of the cycle, it delays the treatment. To overcome the problems in the current diagnostic, a chemdraw highly sensitive biosensor can be developed using a suitable Biomarker. Electrochemical biosensor is one where it measures the electrochemical signal produced during the Language Known: biochemical interaction. In this study, an electrochemical biosensor would be developed using  English, Tamil a suitable material which are highly conductive, and fabrication done based on their sensitivity. Finally, characterization will be done using SEM, FTIR, AFM, POTENSIOSTAT- GALVANOSTAT.

SHITAL SHYAMSUNDAR ROKADE Address: Patil Nagar, Near to sai temple, Umarkhed, Yavatmal, Maharashtra - 445206 Contact no.: +917775962991 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/shital-rokade-5a6949191

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.7 CGPA till 2nd semester 2018 & GPAT 2018

 2014-18: Bachelor of Pharmacy from Government College of Pharmacy, Sant Gadge Baba Skills: Amravati University, Maharashtra with 7.15 CGPA  Fusion360 Autodesk, Dissertation: Biorender  Title: Development of vascularized 3D multiscale polymeric micro/nanofluidic device for solute  Electrospinning, 3D printer, separation. UTM, Optical Microscopy,  Description: Fish gills are one of the most effective gas/solute exchange organs so, to mimic UV-visible spectroscopy, the structure of fish gills, we propose to fabricate a microfluidic device having 3D multiscale Rheometer, DSC, FT-IR vascular network of channels. We envisage to develop a nanovascularised polymer matrices through insitu dispersion of electrospun nanofibers of PVA in a pre-cured PDMS polymer and Language Known: their removal through appropriate solvent after curing of PDMS. Further, 3D printed mold  English, Hindi, Marathi would be used to cast the above PDMS generating a bifurcating microchannels connected to nanovascularised network of channels. These devices would be useful in applications of biomedical and chemical engineering demanding separation activities.

19 VAIBHAV TATYASAHEB SHITOLE Address: Tatborgaon,post-Apegaon,Ambajogai,Beed,Maharastra 431517 Contact no.: +919096323869 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/vaibhav-shitole-5b1a67101

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.67CGPA till 2nd semester 2018 & GPAT 2018

 2014-18: Bachelor of Pharmacy from NDMVP’s College of Pharmacy Nashik, Savitribai Phule Skills: Pune University, Maharashtra with 62.67%  Conversant with 3D Printer, Dissertation: UV, HPLC, DSC, FTIR,  Title: Hydrophilic Supermicroporous Material based micro sampling device for the blood Universal Testing Machine, analysis and diagnostic application. Electrospinning, HSM, HPH,  Description: Blood sampling for diagnosis & drug monitoring is well established process in Zetasizer, Rheometer. current scenario. So, from the market needs and public demands blood sampling process  Good communication skills, Punctual, artistic, creative should be easily accessible and economically viable. Considering these problems and public demands, we are developing blood micro sampling device for blood collection in dried state in Language Known: a porous material. The Advantage of current device over already existing devices is that only  English, Hindi, Marathi few drops of blood requirement, samples stability and prevention from biohazards problems.

DEEPAK VINOD RANGLANI Address: Room number 7/8, Tejaswini apartment, Balwant nagar, Near Saibaba temple, Satpur colony, Nashik-422012 Contact no.: +919595212146 E-mail ID: [email protected] LinkedIn Profile: www.linkedin.com/in/deepak-ranglani-994468193

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 8.26 CGPA till 2nd semester 2018 & GPAT 2018  2014-18: Bachelor of Pharmacy from Savitribai Phule Pune University (Formerly University of Skills: Pune, Maharashtra), India with 63.68%

 Techniques: Electrospinning, Dissertation: DSC, TGA, FT-IR, ATR,  Title: The Next Generation Radiopaque Agent for High Strength and Osteoconductive Bone UTM. Cement  Statistical analysis by  Description: Acrylic bone cements are cold cured solid: liquid system widely used in GraphPad vertebroplasty, kyphoplasty, prosthesis fixation, osteoporosis etc. These cements are  Applications: Origin, prepared by free radical polymerization reaction involving poly (methyl methacrylate), benzoyl ImageJ. peroxide and barium sulphate in solid phase and methyl methacrylate, N, N-Dimethyl-p- toluidine in liquid phase. The real problem associated with currently available acrylic bone Language Known: cements is poor bioactivity and poor mechanical strength which is attributed to the barium  English, Marathi, Hindi, sulphate added as a radiopaque agent. In our project we are trying incorporate radiopaque Sindhi agent barium titanate in place of barium sulphate which due to its piezoelectric property would make the cement bioactive and also which won’t affect the mechanical strength of the cement. This will further be helpful in the bone tissue regeneration due to its bioactivity. 

20 AZMEERA VAMSHI NAIK Address: House No: 2-118, Near school, Azmeera thanda (Village), Ananthigiri (Mandal), Suryapet (Dist), Telangana (state), Pin code:508206. Contact no.: 7032565705 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/vamshi-azmeera-212258193

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical devices from National Institute of Pharmaceutical Education and  Qualified NIPER JEE 2018 & Research (NIPER), Ahmedabad with 6.0 CGPA till 2nd semester GPAT 2018

 2014-18: Bachelor of Pharmacy from Anurag pharmacy college, Jawaharlal Nehru technological university, Hyderabad, Telangana with CGPA 6.45 Skills:  Self-motivative, Time Management Dissertation:  Handling 3D Printer, Electrospinning  Title: Fabrication and characterization of aligned channels in supermacroporous cryogel scaffold.  Knowledge on CURA, AUTOFUSION  Description: Topological cues are the surface which has shape and features that show action and Softwares give signal for something to happen. These cues can be groves and ridges, that have shown to direct axonal growth when are in micron dimensions. Topological cues with groves have shown neuronal Language Known: differentiation of BM-MSCs. In this study, we aim to fabricate topological cues guided  English, Telugu, Hindi supermacroporous cryogels using 3D printed moulds that will align or guide the proliferation and may regulate cell function. Also topological cues imprinted on the collagen cryogels may show faster axonal growth or increases cellular function or activity. Cryogels are gel matrices that are formed in moderately frozen solution of monomeric or polymeric precursors. Cryogels have interconnected micropores allowing uninterepted diffusion of solutes and molecules that may provide nutrition for axonal regeneration. Thus such topological cues with BM-MSC cells guided collagen cryogel may prove to fasten the axonal regeneration into the injured spinal cord.

SHUBHAM RAVINDRA AGIWAL

Address: 8’ Mahesh, Madhuban Co-Op Soc, Kathe Lane, Dwarka, Nashik -422011 Contact no.: +91 955 260 3240 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/shubham-agiwal-819801165

Education: Achievements:  2018-20: M. S. (Pharm.) in Medical Devices from National Institute of Pharmaceutical Education and  GPAT and NIPER JEE qualified. Research (NIPER), Ahmedabad with 8.1 GPA till 2nd Semester.  Won 1st prize in Pharmaceutical  2014-18: Bachelor of Pharmacy from Sir Dr. M.S. Gosavi College of Pharmaceutical Education and Model Making Competition at Research, Nashik. Affiliated to SPPU, Maharashtra with 67.89 % 54th National Pharmacy Week Dissertation: conducted by IPA.  Title: Comparing the Efficacy of Porous Punctal Plugs with the Commercially Available Punctal  Won 2nd prize as a team in Plugs for Dry Eye Disease. Football tournament organized  Description: Dry eye disease (DED) is a multifactorial disease characterized by dry ocular surface. by Western India Football Association. Punctal plugs are the small medical devices, inserted into the puncta region of the eye to block the nasolacrimal duct which in turn prevents the drainage of tears, thus effective in treating DED, Sjogren’ssyndrome, Punctal Stenosis, Cataract, and Glaucoma. The plugs that are currently available Skills: in market are mostly made up of collagen or silicone but they have their own drawbacks like high cost,  Experience of handling instruments migration of the plug, epiphora, rapid degradation. Thus, to curb the dire need of the DED market, we like Electrospinning Unit, Universal fabricated Supermacroporous Collagen Cryogel plugs that has drug Moxifloxacin incorporated into it Mechanical Testing Machine, FDM for treating eye infections. Furthermore, this study aims to compare the efficacy and performance of 3D Printer, Cryogelation Machine, fabricated punctal plugs with the marketed collagen punctal plugs. SEM/Cryo-SEM, Rheometer.  Team Management, Scientific writing Language Known:  English, Hindi, Marathi, Marwadi

21 Department

Of Medicinal

Chemistry

Departmental Expertise:  Design and synthesis of heterocyclic compounds as anticancer and anti-diabetic agents.  Development of new strategies and concepts in synthetic organic chemistry towards sustainable synthesis of NCEs for anti-cancer drug discovery.  Computer aided drug designing, docking, simulation studies and study of (quantitative) structure activity relationship.  Transition metal catalyzed C-H activation reactions of unreactive C-H bond for the synthesis of anticancer and neuroprotective agents.  Design and construction of fluorine containing scaffolds of pharmaceutical importance via C- H Bond activation.  Process development of Active Pharmaceutical Ingredients (APIs).  Repurposing of existing drug molecules for improved PK/PD profiling by modification of non- pharmacophoric parts.  Design and synthesis of peptide-nucleic acids (PNA) targeting m RNA and DNA related to oncology,

neurological and metabolic disorders.  Synthesis of peptides and peptido-mimetics as biomaterials for targeted delivery and various bio-medical applications. 22 ARNAB CHOWDHURY Address: 145, Sarada Lane, Power House Para, Burdwan, Purba Bardhaman, West Bengal -713101. Contact no.: +918759966606, +918758871391 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/arnab-chowdhury-aa4abb122

Education: Achievements:  2018-2020: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 Education and Research (NIPER), Ahmedabad with 8.87 CGPA till 2nd semester and GPAT 2018  2014-2018: Bachelor of Pharmacy from NSHM Knowledge Campus, , University:  Qualified CUCET 2018 in Maulana Abul Kalam Azad University of Technology, West Bengal with 9.02 CGPA Pharmaceutical Chemistry Dissertation: with AIR 1st  Title: Design and synthesis of acetylated stilbenoids for tumor PYRUVATE KINASE M2 Skills: (PKM2) modulation  Good Instrument Handling,  Description: To avoid the conventional cancer treatments due to their immense side effects I Rota evaporator, Microwave am synthesising some Multi Targeted Directed Ligands (MTDL) with immuno-oncogenic synthesis reactor, skills properties which will directedly target the cancer cell metabolism. The main target of these interpretation of UV, IR, NMR compounds will be PKM2 which is present in dimeric form in cancer cells and inactive in nature. The main pharmacophore of these compounds is substituted stilbenoids with an acid having Language Known: anti-cancer activity attached with an ester bond. Within the body the breakdown of these ester  English, Hindi, Bengali bond will produce a hydroxylated stilbenoids having anti-PKM2 activity and the acids will show other anticancer activities.

MEENAKSHI CHAURASIA Address: H.no.30, Vaishali nagar, near new kamla nagar thana, Kotra, Sultanabad, Bhopal, Madhya Pradesh, 462003. Contact no.: +919329548577 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/meenakshi-chaurasia-2944b2144

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 6.45 CGPA till 2nd semester Qualified GPAT 2018  2013-17: Bachelor of Pharmacy from Sagar Institute of Research and Technology-Pharmacy,  Completed my bachelor’s Rajiv Gandhi Prodyogiki Vishwavidyalaya, Bhopal, Madhya Pradesh with 7.77 CGPA degree with honors Dissertation: Skills:  Title: Synthesis and characterization of novel gem-difluoro containing coumarin  Office, Laboratory  Description: apparatus like Rota evaporator, Furane fused heterocyclic system has been reported for several therapeutic uses. The Rotary tablet punching machine, incorporation of fluorine atom in organic molecules enhances the physicochemical properties Analytical instruments like UV- like lipophilicity, bioavailability and metabolic stability. We will use an approach for the Vis Spectrophotometer & have synthesis of gem-difluorofurancoumarins which will predicted to have an anticancer activity. skills in interpretation of UV, IR, NMR, Mass Language Known:  English, Hindi,

23 BHASKAR DEWANGAN Address: H. No. 23, Infront of Pal Complex, Behind Priya fancy House, Jal Grih Marg, Tikrapara, Raipur, Chhattisgarh, 492001. Contact no.: +918358855585 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/bhaskar-dewangan-69b762192

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 6.03 CGPA till 2nd semester. GPAT 2018  2014-18: Bachelor of Pharmacy from University Institute of Pharmacy, Pt Ravishankar Shukla  Qualified State PPHT 2014 – University, Raipur, Chhattisgarh with 70.65%. Rank 555.

Dissertation:  Title: Multi-modal hexaflourocarbinol containing triazol-4-methyl amines as anti-amyloid Skills: compounds; Design, Synthesis and Evaluation.  Handling of instruments :  Description: Alzheimer’s disease (AD) is the age-linked neurodegenerative disorder. Beta Rotavapor, Parallel amyloid aggregation, ROS generation, bio-metals dyshomeostasis (Fe, Cu and Zn) in the brain synthesizer, FTIR. involves in the pathogenesis of AD. Our team is trying to develop a series of molecules for AD  Software's: Chem-Bio Draw, treatment. In our designed molecule containing phenyl and triazole moiety which may possess Bruker TopSpin, EndNote various properties i.e. metal chelation activity, beta amyloid intercalator property, anti- inflammatory activity. Language Known:  English, Hindi, Chhattisgarhi

DEEP ROHAN CHATTERJEE Address: 10, R.B.C. Road (Extension), Dum Dum Cantonment,South Dum Dum, North 24 Parganas, Kolkata – 700028. Contact no.: +919830825616 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/deep-rohan-chatterjee-943911112

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  GPAT 2018 and NIPER JEE Education and Research (NIPER), Ahmedabad with 7.2 CGPA till 2nd semester. 2018 Qualified.  2014-18: Bachelor of Pharmacy from Guru Nanak Institute of Pharmaceutical Education &  Participated in Online Prelims Research (GNIPST), Maulana Abul Kalam Azad University of Technology (MAKAUT), West of 69th IPC Pharma Quiz 2017 Bengal with 8.64 CGPA  Runners up of Inter NIPER Football competition 2019. Dissertation:  Title: Synthesis of 2-Alkyl and 2-Conjugated Styryl Quinazolin-4(3H)-one Derivatives as Skills: Potential HDAC Inhibitors  Good hand at synthesis and  Description: column and their troubleshoot. In this new era of cancer treatment, where epigenetic modifications are making the headlines  Instrument handling : Rotavapor, for all good reasons, HDAC has become one of the most important target for treatment of Microwave synthesizer, Parallel cancer by prevention of certain changes that it does during Post Translational Modifications synthesizer, FTIR (PTM). My dissertation work focuses on utilization of Quinazolinone derivatives as HDAC  Schrodinger Maestro, Chem inhibitors to treat cancer effectively. I have generated a library of 20 molecules of substituted Office, Autodock, Opus. 2-Alkyl and 2-Conjugated Styryl Quinazolinone derivatives based on in silico studies. I have checked its activity (in silico) in those HDAC isoforms related to cancer. Language Known:  English, Hindi, Bengali

24 AYUSHI SHARMA Address: R-15 A Block silicon city (M.P), 452001 Contact no.: +919157851406 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/ayushi-sharma-310232193

Education: Achievements:  2018-20: M. S. (Pharm.) in [Medicinal Chemistry] from National Institute of Pharmaceutical  Qualified GPAT 2018 and Education and Research (NIPER), Ahmedabad with 8.38 CGPA till 2nd semester NIPER JEE 2018  2014-18: Bachelor of Pharmacy from IPS Academy-Indore, Rajiv Gandhi Prodyogiki  Completed my bachelor’s Vishwavidyalaya, Bhopal, Madhya Pradesh with 8.00 CGPA degree with honors Dissertation: Skills:  Title: Formation of hybrid styryl moieties following one pot synthesis for anticancer activity  Microsoft Office, Laboratory  Description: apparatus like Rota Formation of the hybrid styryl moieties following one pot synthesis by using Mizoroki Heck evaporator, Rotary tablet type reaction for C-C coupling, to show promising results towards the target PKM2 and punching machine, Analytical potent anticancer activity from the already existing ones. instruments like UV-Vis Spectrophotometer & have skills in interpretation of UV, IR, NMR, Mass Language Known:  English, Hindi,

SAGAR DILIP POTKULE Address: At- Garudeshwar, Post- Mundhegaon, Tal- Igatpuri, Dist- Nashik, Maharashtra, 422403 Contact no.: +919765980258 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/sagar-potkule-44a748175

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE and Education and Research (NIPER), Ahmedabad with 6.4 CGPA till 2nd semester. GPAT 2018.  2014-18: Bachelor of Pharmacy from S.M.B.T College of pharmacy, Nashik, Pune University, Skills: Maharashtra with 60 %.  Efficient in instrument handling Dissertation: like, UV, FT-IR, Column  Title: Synthesis and characterization of novel dihydrofuran fused coumarin analogues. chromatography, Rotary Description: Natural as well as synthetic coumarins have recently drawn much attention evaporator, microwave synthesis due to its broad pharmacological activities like anti-coagulant, anti-tumor, anti-viral, anti- reactor inflammatory and antioxidant effects, as well as anti-microbial and enzyme inhibition  Software's: Chem-Bio Draw, properties. The coumarin family is crucial for the design and development of new analogues Bruker TopSpin, EndNote, with improved activity and for the characterization of their mechanism of action and potential Mendeley, AutoDock, side effects. The different substituents in the coumarin nucleus strongly influence the MestReNova Lite. biological activity of the resulting derivatives so the present work highlight’s the development of dihydrofuran substituted coumarin scaffolds for drug discovery as novel antimicrobial, Language Known: antiviral and anti-cancer agents.  English, Hindi, Marathi

25 TANAY MAHESH DALVI Address: B-205, Shankar Heights, Phase 1, near Father Agnel school, Ambernath West, Maharashtra – 421501. Contact no.: +917718816485 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/tanaydalvi07

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 and Education and Research (NIPER), Ahmedabad with 8.86 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from Dr. L. H. Hiranandani College of Pharmacy,  Secured 2nd position in paper University of Mumbai, Maharashtra with 7.88 CGPA presentation at Rx Mélange 2018. Dissertation:  Secured 1st position in poster  Title: Design, synthesis and evaluation of multi-target directed hexafluorocarbinol presentation at Pharmazest 2017. containing triazole-4-carboxamides as inhibitors for amyloid β aggregation. Skills:  Description: Alzheimer’s disease is a progressive neurodegenerative disease which involves the degeneration of cholinergic neurons. Amyloid β aggregation resulting into  Proficient with Autodock, plaque formation is one of the characteristic hallmarks of the disease. Metal ion Topspin, Mendeley, dysregulation plays an important role in the formation of these plaques and also leads to Chembiodraw, Microsoft Excel oxidative stress and neuroinflammation. Thus, our research is focused on the chelation of and Powerpoint. these excess metal ions by using triazole based compounds containing hexafluorocarbinol  Handling of instruments like group, thereby providing a multitarget directed approach by inhibiting metal induced amyloid Rotary evaporator, FTIR, UV spectrophotometer, Microwave β plaque formation and also preventing oxidative stress and neuroinflammation. synthesis reactor etc.

Language Known:  English, Hindi, Marathi, Konkani

MITHILESH NAGPURE Address: 69, Dongariya village-Dongariya, Post-Amai,Tehsil-Khairlanji, Balaghat Madhya Pradesh 481335 Contact no.: +918959742780 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/mithilesh-nagpure-2a0761192

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.27 CGPA till 2nd semester 2018 & GPAT 2018  2014-18: Bachelor of Pharmacy from Globus College of Pharmacy Bhopal, University Rajiv Skills: Gandhi Proudyogiki Vishwavidyalaya Bhopal, Madhya Pradesh with 7.44 CGPA  Efficient in instrument handling Dissertation: like, UV, FT-IR, Column  Title: Sustainable Synthesis of Flunarizine Using Metal Free N-Allylation as Key Synthetic Chromatography, Rotary Step evaporator.  Description: The N-cinnamyl piperazine is the major precursor of flunarizine drug, mainly Language Known: synthesized via transition metal catalyzed N-allylation reaction, but the use of highly reactive  English, Hindi and expensive metal species, side reactions, metallic waste becomes major drawback. Herein, we are developing metal free protocol for cost effective sustainable synthesis of flunarizine drug.

26 NEHANAZ FAIYAZHUSAIN SAIYED Address : Saiyedwada, Nr.Gariyapir Masjid, Petlad, Gujarat-388450 Contact no. : 9624151786 E-mail ID : [email protected] LinkedIn Profile : https://www.linkedin.com/in/nehanaz-saiyed-246220193

Education: Achievements:  2018-20: M.S.(Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 8.16 CGPA till 2nd semester. GPAT 2018

 2014-18: Bachelor of Pharmacy from A.R.College of Pharmacy and G.H.Patel Institute of Skills: Pharmacy, Vallabh Vidhyanagar, Gujarat Technological University, Gujarat with 8.30 CGPA.  Handling of instruments like Dissertation: Rotary evaporator, FT-IR,  Title: Synthesis and characterization of fluorinated 9H-Pyrrolo[1,2-a]indole Column Chromatography.  Description: 9H-Pyrrolo[1,2-a]indole scaffold synthesis by the cyclization of alkyne chain through radical based mechanism. Various radical initiators are used to generate vinylic radical which is subsequently cyclized and then isomerizes to give 9H-Pyrrolo[1,2-a]indole. Languages Known: Incorporation of fluorine into the 9H-Pyrrolo[1,2-a]indole leads to increased lipophilicity, English, Hindi, Gujarati increased metabolic stability and alter the physicochemical properties.

JYOTI RANI Address: Vill. and Post Office Baroh, Teh. Bhoranj, Distt. Hamirpur, Himachal Pradesh-177024 Contact no.: +919882689983 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/jyoti-rani-40658b10b

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 6.82 CGPA till 2nd semester Qualified GPAT 2018  2010-2014: Bachelor of Pharmacy from Himachal Institute of Pharmaceutical Education and Research (HIPER), Nadaun (H.P.), Himachal Pradesh University, Shimla, with 75% marks  Qualified NIPER JEE 2014 & Qualified GPAT 2014 Dissertation:  Title: Design, synthesis and biological evaluation of novel hexa-fluorocarbinol containing Skills: benzfused stilbenes for Alzheimer’s disease targeting neuroinflammation.  Industry Knowledge Description: Alzheimer’s disease (AD) is recognized as a progressive neurodegenerative  Instruments Knowledge (UV, IR, disorder which causes dementia among elderly people. Drugs hitting a single target may be HPLC) inadequate for the treatment of diseases like neurodegenerative syndromes which involve  Presentation Skills multiple pathogenic factors. Hence, the concept of Multi-Target Directed Ligands (MTDLs)  Computer skills approach to drug discovery comes into picture. We have designed hexafluorocarbinol substituted benzfused stilbenes as multitarget directed ligands for simultaneous inhibition of Language Known: amyloid-β and exhibit anti-inflammation. This designed novel molecules will be synthesized  English, Hindi and evaluated for their biological activity. Aided by in-silico study, structure activity relationship will be established for the designed scaffold.

27 POOJA RANA

Address: B-8/106,Sector-4, Rohini, Delhi-110085 Contact no.: +91 8469477324 E-mail ID: [email protected] LinkedIn Profile: http://linkedin.com/in/pooja-rana-6638a4163\

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 Education and Research (NIPER), Ahmedabad with 7.90 CGPA till 2nd semester.  Qualified GPAT 2018  2014-18: Bachelor of Pharmacy from Delhi Institute of Pharmaceutical Sciences and Research, Delhi University, Delhi with 68.37 %. Skills: Dissertation:  Efficient in handling analytical  Title: Synthesis of 2-styryl quinazolinones as HDAC inhibitors. instrument like FT-IR, ATR,  Description: Cancer is a group of disease, which is characterized by uncontrolled cell UV-vis spectrophotometer. growth and have potential to invade inside normal cells and tissues. It has been seen that in  Proficient in handling cancer histone deacetylase (HDAC) enzyme activity get altered which is major cause of instruments used in the field of various kind of cancer. So, the compounds having potential to inhibit histone deacetylase drug discovery like rotary may serve the purpose for treating cancer. Recently HDAC inhibitors have been emerged in evaporator, probe sonicator. the field of anticancer drugs. The histone deacetylase inhibitors have ability to inhibit the  Knowledge of software like proliferation of cancer cells by arresting the cell cycle and hence restrain the growth of cancer endnote, Mendeley, cells. SAHA is a drug which comes under the class of HDAC inhibitor has got approval from Chemdraw, MestRenova. FDA for the treatment of cutaneous T-cell lymphoma. Pharmacophore of styryl quinazolinones show similarities in structures with SAHA as it contains cap, linker and zinc Language Known: binding group and hence, we are trying to synthesize different derivatives of styryl  English, Hindi quinazolinones which may serve as potential HDAC inhibitors and which will be further evaluated for its biological activity.

SURBHIBEN MOHANLAL DESAI Address: 304-A, Anand Apartment, Station Road, Killa Pardi, Valsad, Gujarat -396125 Contact no.: +916355420880 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/surbhi-desai-598819177

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 and Education and Research (NIPER), Ahmedabad with 8.86 CGPA till 2nd semester. GPAT 2018

 2014-18: Bachelor of Pharmacy from Smt. B.N.B Swaminarayan Pharmacy College, Gujarat Skills: Technological University (Gujarat) with 9.16 CGPA.  Verbal skills Dissertation:  Representation skills  Title: Catalytic alkyne annulation for the construction of tricyclic 9H-Pyrrolo[1,2-a] indole framework Language Known: Description: Pyrrolo[1,2-a] indole scaffold synthesis by the cyclization of alkyne chain  English, Hindi, Gujarati through radical based mechanism. Various radical initiators are used to generate the vinylic radical and subsequently the cyclization, giving the pyrroloindole scaffold.

28

ASHWINI. V. Address: # 5, 1st 'A' cross, Preethinagar, Laggere, Bengaluru - 58. Contact no.: +917760754454 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/ashwini-v-395781145

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 9.33 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from M. S. Ramaiah University of Applied Sciences,  Qualified Karnataka PG-CET Karnataka with 8.17 CGPA. 2018 with Rank 1.

Dissertation: Skills:  Title: Allyl N -Heterocycles: Synthesis and Bio-Evaluation for their Anti-Cancer activity  Quick learner & Dedicative  Description: Transition metal catalysis for allylation of N-Heterocycles has been well  Good at oral & written established. Though these are popular enough because of the drawbacks associated with communication the use of metals, there is a need for an alternative approach. Hence, we are trying to  Technical skills - Microsoft office, develop a novel metal-free protocol for allylation of N-Heterocycles which would serve as a Excel, Power point proficiency. superior approach than existing ones. Language Known:  English, Kannada, Hindi

PAYAL DILIP MESHRAM Address: Gautam buddha ward,Railway chauky,Khairlanji road,Tirora, Dist.Gondia, Maharashtra, 441911 India. Contact no.: +917769095798 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/ in/ payalmeshram -396949191

Achievements: Education:  Qualified NIPER JEE 2018 &  2018-20: M. S. (Pharm.) in [Medicinal Chemistry] from National Institute of Pharmaceutical GPAT 2018 Education and Research (NIPER), Ahmadabad with 6.2 CGPA till 2nd semester Skills:  2014-18: Bachelor of Pharmacy from University department of pharmaceutical sciences  Enthusiastic Nagpur, Rashtrasant Tukadoji Maharaj Nagpur University, Maharashtra with 7.01 CGPA  Computer Literacy Dissertation:  Ability to work in team and  Title: Synthesis of styryl –chalcone hybrids as PKM2 modulators using one pot procedure individually as well Description: Formation of styryl –chalcone hybrids using one pot procedure followed by  Graphical design Mizoroki Heck type reaction which may show potent PKM2 modulatory action and use as  Handling experience with potent anticancer agent than that of already existing one. instruments like Rota evaporator, Analytical instrument like UV- Visible spectrophotometer  Have skills in interpretation of NMR, IR Language Known:  English, Hindi, Marathi

29 DAS Address: 2A, Chandra Nath Simlai Lane, Kolkata, West Bengal- 700002 Contact no.: +91-7044563366 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/anwesha-das-7145a411b

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical Education and  Qualified NIPER JEE 2018 & Research (NIPER), Ahmedabad with 6.25 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from NSHM Knowledge Campus- Kolkata Group of Institutions,  Achieved certificate for attending & Maulana Abul Kalam Azad University of Technology (Formerly known as West Bengal University of presenting poster in NATCONPH Technology), West Bengal with 8.40 CGPA (National Conference) & iNATCONPH (international Dissertation: Conference) held at NSHM  Title: Synthesis of Hydroxylated Stilbenoids for tumor Pyruvate Kinase M2 (PKM2) Modulation Knowledge Campus- Kolkata Description: Emerging evidences show that dysregulated Warburg-like glucose metabolism is linked Group of Institutions to therapeutic resistance in cancer treatment. Therefore, targeting cancer cell metabolism may Skills: represent a promising strategy to overcome the drug resistance in cancer therapy in comparison with  Handling of Rotary Evaporator, the conventional anticancer mechanism targeting. PKM2, an isoform of Pyruvate Kinase (PK) enzyme, is an exclusive example of a critical regulator in cancer cell metabolism & is responsible for cancer Column Chromatography, Thin Layer Chromatography & metabolism & tumor growth. PKM2 acts as a key regulator in maintaining the balance between energy Conventional IR Spectrophotometer needs (tetramer) & building block needs (dimer) for increasing biomass. Several previous studies  revealed that restoring the dimeric activity of PKM2 into its tetrameric level or inhibiting the dimeric PKM2 Endnote, Chemdraw, Chembiodraw, may revert the cancer cell to a metabolic state like that of a normal cell. It is reported that Resveratrol MNova, Topspin, Mendeley, downregulates PKM2 expression by inhibiting mTOR signaling pathway, suppresses cancer  MS- Word, PowerPoint, Excel, metabolism, decreases glucose uptake & lactate production (aerobic glycolysis) in various cancer cell Publisher  Extracurricular Activity- Singing lines. Also, dichloroacetic acid (DCA) is having Pyruvate Dehydrogenase Kinase (PDK) inhibitory property. But due to Resveratrol’s poor oral bioavailability (less than 1%) & DCA’s toxicity & numerous side effects such as pneumonitis & dyspnea etc., they can’t be given solely to the patients. Hence, our Language Known: aim will be synthesizing of Stilbenoids/ DCA hybrids which may target PKM2 which will then be English, Hindi, Bengali hydrolyzed in-vivo into Resveratrol-like-stilbenoids & DCA.

MANISH KUMAR Address: 304 –A , Nirman Society, Near Bus Station, Kapadwanj , Dist: Kheda, PIN: 387620 Contact no.:7877789072 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/manish-purohit-b02481193

Education: Achievements:  2018-20: M. S. (Pharm.) in Medicinal Chemistry from National Institute of Pharmaceutical Education and  Qualified GPAT 2019 AIR – 48 Research (NIPER), Ahmedabad with 7.03 CGPA till 2nd semester.  Qualified NIPER JEE 2018  2014-18: Bachelor of Pharmacy from Arya College of Pharmacy (), Rajasthan University of Health  Qualified GPAT 2018 AIR - 42 Science (Rajasthan) with 70 %  Qualified GPAT 2017 AIR -236 Dissertation:  AIIMS M.Sc. (Pharmacology) 2018 AIR – 4 Title: Cross Talk of Critical Quality Attributes (CQA) and Critical Process Parameters (CPP) of Biodegradable PLGA Polymer: A Systematic Study. Skills: Description: Synthesis of PLGA polymer by condensation reaction and studying the effects of Process  Verbal Skills Parameters on the Quality attributes of the product and in turn onto the formulation aspects of the Polymer. Language Known:  English, Hindi, Gujrati

30 Department

Of Natural

Products

Departmental Expertise:  Bioprospecting endolichenic fungi from Mangroves in Negombo Lagoon in and Gulf of Kutch and in Gujarat India; an untapped treasure trove for the discovery of special structures and bioactive compounds.  Application of LC-MS based dereplication strategy for isolation of natural products from microbial and plant sources.  Bioassay guided extraction and isolation of secondary metabolites from Plants and their structure elucidation.  Identification and characterization of small MW peptides/cyclic peptides/small molecules from plants to find a cure for type 2 diabetes mellitus.  Modification of bioactive Natural Products (hit) via SAR based semi-synthesis  Development of herbal nanoformulation like phytosomes and nanoparticles of enriched plant extract or bioactive markers.  Standardization of plant extracts and herbal formulations with respect of marker constituents using UPLC-

PDA, LC-UV-MS and qNMR techniques.  Study on the influence of processing methods (as per Ayurveda) on chemical constituents of plants /herbal formulations 31 AMARNATH HATUI Address: kuldunga,Dist:Howrah,Ps: Panchla,711302,Kolkata, West Bengal Contact no.: +919051621096 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/amarnath-hatui-a6541716a

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.1 CGPA till 2nd semester 2018 & GPAT 2018  2014-18: Bachelor of Pharmacy from BHARAT TECHNOLOGY under MAULANA ABUL  1st position in 2nd sem in B- KALAM AZAD UNIVERSITY OF TECHNOLOGY, West Bengal with 8.57 CGPA Pharm Skills: Dissertation:  Title: Development of Novel anticancer analogous of ACETYL-11-KETO-β-BOSWELLIC ACID  Handling of analytical (AKBA) AND 11-KETO-β-BOSWELLIC ACID (KBA). instruments (HPLC, FTIR,  Description: The American Cancer Society estimates the numbers of new cancer cases and UV, FLASH) deaths every year. I am trying to development of potent anticancer molecule from plant against  Knowledge about different target. From Boswellia serrata isolate the ACETYL-11-KETO-β-BOSWELLIC ACID computational chemistry (AKBA) AND 11-KETO-β-BOSWELLIC ACID (KBA) and development of amide type (Docking) derivatives of AKBA &KBA by modification at A ring. In-silico study of these compound against different target protein and In-vitro study also done against different cell line. Language Known:  English, Hindi, Bengali

ANJALI BITLA Address: Flat no. 204, Sreenivasam Nilayam Apartments, Anjaneya Nagar, Boduppal, Medchal(District), Hyderabad,Telangana- 500092. Contact no.: +919550243006, 7013761887 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/anjali-bitla-619382193

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.16 CGPA till 2nd semester 2018 & GPAT 2017  2013-17: Bachelor of Pharmacy from Bojjam Narasimhulu Pharmacy College for Women,  Qualified BITS higher Jawaharlal Nehru Technological University Hyderabad, Telangana with 78.97% degree test 2018 Dissertation:  TSPGECET 2017 Rank 71, Percentile 96.51 %  Title: Isolation and Identification of Quassinoids from Ailanthus excelsa Roxb for Anticancer activity Skills:  Description: Existing treatments for cancer therapy are costly and associated with several  Handling of HPLC, Flash adverse effects. So, there is need of safer, specific and cost effective drugs. Natural Products chromatography, UV-Vis, IR, based drugs are always being considered as safe and potent. Quassinoids class of etc. & Professional Software phytoconstituents has shown promising anticancer activity on many cell lines. Bruceantin is one of these which have reached up to phase-II clinical trials. In Ayurveda Ailanthus excelsa  Hard Worker, Team Player is reported for treatment of various diseases. So, the phytochemical investigation could end up with new quassinoids with potent anticancer activity. Language Known:  English, Hindi, Telugu

32 ANKITA PRAFULLA CHOPADE Address: Shantanu Heights, Fl-C-01, Vitthal Darshan, Alandi road, Bhosari, Pune, 411039 Contact no.: +919689915338, +919823276794 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/ankita-chopade-a34aa5148

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.27 CGPA till 2nd semester 2018 & GPAT 2018

 2014-18: Bachelor of Pharmacy from PES, Modern College of Pharmacy (for Ladies), Skills: Savitribai Phule Pune University, Maharashtra State with 67.77 %  Handling experience with Dissertation: instruments like Rotary  Title: Chemical Investigations on Ayurvedic Formulations used for Type 2 Diabetes containing evaporator UV Tinospora cordifoila and Commiphora weightii Spectrophotometer, pH  Description: Various type of Ayurvedic formulations are mentioned in ‘Ayurvedic Formulary meter of India.’ Medicinal plants extracts have shown anti diabetic activity and have been shown to  Have skills in interpretation restore the action of pancreatic β- cells with less side effects. The emphasis shall be on of IR, NMR isolation and characterization of phytoconstituents from these plants for diabetes mellitus. The plants will be subjected to the procedures as mentioned in their formulations type and Language Known: phytoconstituents will be isolated.  English, Hindi, Marathi

SRILEKHA PULI Address: D/O Bhaskara rao, DO NO 32-30-4/30, Bhagath Singh Nagar, OPP Andhra bank, Machavaram, Vijayawada, Krishna, Andhra Pradesh, 520004. Contact no.: +918464877539 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/srilekha-puli-34795611b

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 8.33 CGPA till 2nd semester 2018 & GPAT 2018  2014-18: Bachelor of Pharmacy from K.V.S.R. Siddhartha College of Pharmaceutical Skills: Sciences, Vijayawada, Andhra Pradesh with 8.75 CGPA.  Handling experience with Dissertation: instruments like Rotary  Title: Isolation and Characterization of Neuroprotective Constituents from Aloe vera. evaporator, flash  Description: Neuroprotection is the preservation of structure and function of neurons from the chromatography and cellular injuries induced by a variety of agents and neurodegenerative diseases (NDs) which analytical instruments like involves the strategies and relative mechanisms that shield the CNS. Neuroprotective effects UV-Vis Spectrophotometer, of Aloe vera were reported in the traditional system of medicine. Our research aims at isolating HPLC. the neuroprotective constituents with minimal side effects from the Aloe vera in the manner as  Have skills in interpretation they were done in traditional system of medicine (Ayurveda) and comparing with the of UV, IR, Mass, NMR. commercial methods of extraction. This research helps in bridging the gap between traditional system of medicine and modern medicine by providing scientifically authorized and validated Language Known: data for the Ayurvedic system of medicine. The work done may probably end up with  English, Hindi, Telugu increasing market share of the Ayurvedic formulations and thus improving the quality of life.

33 ROHIT RAVINDRA SHEJUL Address: 4-5-177, Shejul Niwas, Near Hanuman Mandir, Khokadpura, Aurangabad, Maharashtra, India - 431001. Contact no.: +918806991177 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/rohit-shejul-348125169

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 8.00 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from Y. B. Chavan College of Pharmacy, Aurangabad,  Lean Six Sigma White Belt Dr. Babasaheb Ambedkar Marathwada University, Maharashtra with 69.81 % (CSSC) Dissertation:  Selected for Regional Mentoring Session for Proof of Concept (PoC) by MHRD’s Innovation Cell  Title: Phytochemical Investigations on Calotropis procera (Aiton) leaves Skills:  Description: According to previous study Calotropis procera (Aiton) widely used in the  Handling of instruments used for traditional system of medicines (Ayurveda) for the treatment of various ailments. Many Isolation, Characterization, Method constituents are reported from Calotropis procera (Aiton) and different extracts have Development & Validation & shown various types of pharmacological responses, but aqueous extract is not much Structural Elucidation of Natural explored. However, Calotropis procera (Aiton) has not been investigated based on the Products & Professional Software, way it is used (treated) in the Ayurvedic formulations. The aim of the present work is Data Interpretation

to develop extraction procedure based upon procedures of particular Ayurvedic Language Known: formulations to explore bioactive constituents and elucidate their structure which will  English, Hindi, Marathi be helpful in developing much more potential molecule having potent cytotoxic activity.

JINAL KIRTI MITHIYA Address: 302, A wing, hari nivas, sector 26, koprigav, Navi Mumbai-4006043 Contact no.: +918433535639 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/jinal-mithiya-199380193

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 8.6 CGPA till 2nd semester GPAT 2018

 2014-18: Bachelor of Pharmacy from Vivekanand College of Pharmacy, Mumbai Skills: University, Maharashtra State with 7.9 CGPA  Handling experience with Dissertation: instruments like Rotary evaporator and analytical instruments like UV-  Title: Extraction, isolation and characterization of novel anticancer molecules from Vis Spectrophotometer, HPLC Ipomoea carnea Language Known:  Description:  English, Hindi, Gujarati, Marathi Ipomoea carnea is commonly known as pink morning glory there are literature mentioning extract level activity of this plant we are trying to work on its molecular level and expecting isolation of some novel molecule with potent anticancer activity

34 POOJA MADAN RATHOD Address: MHADA Colony Devlai Parisar, Home No-243, Devlai, Aurangabad, Maharashtra- 431002 Contact no.: +917387763063 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/pooja-rathod-32b37a193

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 8.63 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from Government College of Pharmacy  2nd prize in cricket at INSM 2018 Aurangabad, Dr. Babasaheb Ambedkar Marathwada University, Maharashtra with  3rd prize in dodgeball state 64.87 % competetion Dissertation: Skills:  Title: Isolation and Characterization of anticancer molecule from endolichenic fungi  Handling experience of UV, HPLC,  Description: DST funded Collaborative Project between India and Sri Lanka Flash and Vacuum Endolichenic fungi from gulf of Khambhat situated in Gujarat are comparatively less Chromatography, can perform explored in case of drug discovery, hence there is probability that we can get novel culturing and fermentation very bioactive molecule from these fungi. This will be done by collection of 5 lichens from efficiently mangroves of gulf of Khambhat, Gujarat, India followed by isolation of ELF, culturing,  Softwares: ChemBioDraw, DNP, extraction and in vitro anticancer activity evaluation. Screening will be done by Mendeley, Schrodinger, TopSpin dereplication technique with the help of LC-MS. Language Known:  English, Hindi, Marathi

PREETI BACHCHANLAL BHARATIYA Address: 503, D- Wing, Panvelkar Royal Square, Hendrepada, Badlapur West, Thane- 421503 Contact no.: +918108062792 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/preetibharatiya-47a936145

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 8.73 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from Dr. L. H. Hiranandani College of Pharmacy,  Gold medalist, 2018 (B. Pharm)

Mumbai University, Maharashtra with 8.08 CGPA Skills: Dissertation:  Technical skills: Well-versed with  Title: Bioprospecting of endolichenic fungi, to isolate, identify, the novel bioactive fungal culture and fermentation, molecule by applying dereplication strategy DNA extraction, Isolation and  Description: India-Sri Lanka Collaborative Project, funded by DST: Endolichenic characterization of metabolite, fungi is considered as potential source for production of array of secondary metabolite Hands on various analytical tools. with desired pharmacological action. Collection, cultivation of ELF from gulf of  Software skills: ChemBioDraw, Khambhat performed, followed by large scale fermentation, extraction and isolation of Dictionary of Natural Products, molecule by column chromatography. The novel molecule isolated confirmed by AutoDock, Mendeley, TopSpin, applying Dereplication strategy using various analytical tool like LC-MS and comparing Schrodinger with the database in dictionary of natural products. Further molecule can be explored invitro activity for the treatment of any disorder or disease in world. Language Known:  English, Hindi, Marathi

35 UJJAL NASKAR Address: Vill: South kalikapur, P.O: B-Gobindapur, Dist: South 24 parganas, P.S:Bhangar, West Bengal, 743502 Contact no.: +917719113030 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/ujjal-naskar-0a942b104

Education: Achievements:  2018-20: M. S. (Pharm.) in Natural Products from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 5.67 CGPA till 2nd semester. 2018 - AIR 1425 &  2014-18: Bachelor of Pharmacy from Bengal College of Pharmaceutical Sciences and Qualified GPAT 2018 - Research, University of Maulana Abul Kalam Azad University, West Bengal with 7.53 CGPA. AIR 4021

Dissertation: Skills:  Title: Effects of Grapefruit juice and Pomegranate juice on Pharmacokinetics of  Column chromatography, Swertiamarin Having Anti-diabetic Potential in Rat. DSC, FTIR, Rota  Description: We attempt to ascertain the food-drug interaction fallacies between a glycoside Evaporator, UV-Visible molecule, swertiamarin in grape juice and pomegranate juice. Grapefruit juice containing spectroscopy, Analytical furanocoumarin and pomegranate juice containing ellagic acid acts by inhibiting the enzymes Instruments, TLC which are crucial for drug metabolism. Hence inhibition of the enzyme affects the metabolism optimization of the drug in our body, giving the drug to retain for a considerably longer duration into the  Writing and Management body and roots up to the toxicity. Considering the consequences, we even ventured into the co-administration of swertiamarin and the two fruit juices to check the changes into Language Known: pharmacokinetic profile of swertiamarin. Hence, this project is touched with isolation and  English, Bengali, Hindi purification of swertiamarin from Enicostemma littorale plant extract, followed by characterization of swertiamarin. Further to check the effects grapefruit juice and pomegranate juice on pharmacokinetic parameters of swertiamarin having anti-diabetic potential in rat, we would be performing Bioanalytical method development and validation in rat plasma.

36 Department

Of Pharmaceutical Analysis

Departmental Expertise:

 QbD based analytical and bioanalytical method development and validation  PK studies and metabolite profiling  LC-MS and NMR based impurity profiling of NCEs and approved drugs  Metabolite profiling  Toxicokinetic profiling  Compatibility analysis  Reverse engineering of complex products and sameness strategy development for regulatory submission  Degradation profiling of drug substances and drug products  Pre-formulation assessment of drugs including polymorph characterization and drug- excipient compatibility studies

 Stability analysis of drug substance, intermediates and products  Characterization of complex generics and biosimilars 37 DALIP KUMAR Address: Ward No. 4, Near Vijeta Model Senior Secondary School, New Khunja, Hanumangarh Junction, Rajasthan. 335512 Contact no.: +917726912579 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/dalip-sharma-2461b5127

Education: Achievements:  Qualified NIPER JEE 2018 &  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical GPAT 2018 Education and Research (NIPER), Ahmedabad with 8.70 CGPA till 2nd semester  Felicitated by IPGA  2014-18: Bachelor of Pharmacy from Arya College of Pharmacy (ACP), Rajasthan Rajasthan State Branch for University of Health Science (RUHS), Rajasthan with 72.80 % securing 1st Rank in GPAT in Rajasthan

Dissertation: Skills:  Development of Analytical Approach for Characterization of Complex Derivative Of Title:  Hands on experience of HPLC, Hyaluronic Acid FT-IR, U.V, DSC, GPC, column  Description: chromatography and rotary Our collaborator has developed Hyaluronic acid polyamine complex for RNA delivery. This evaporator , Zetasizer and complex polymer will work as new excipient, but for any new excipient, according to USP, it interpretation of all data along should comply with the quality check list provided in the pharmacopoeia before its with software pharmaceutical use. Thus, it is a need of an hour to develop analytical methods for Language Known: characterization and analyses as per regulatory requirement, which can potentially provide  translation value for this novel excipient. English, Hindi, Punjabi, Rajasthani, Haryanvi

ADINATH MUNDE Address: At-Gopalpur, Ta-Kille Dharur, Dist.-Beed, Post office -Kille Dharur, Maharashtra-431124 Contact no.: +91-8657535699 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/adinath-munde-0bbaa8153

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 6.40 CGPA till 2nd semester. 2018 and GPAT 2018  2014-18: Bachelor of Pharmacy from Maharashtra College of Pharmacy Nilanga,Swami Skills: Ramanand Teerth Marathwada University Nanded,Maharashtra with 8.00 CGPA.  Experience in Handling of Dissertation: instruments like DSC,  Title: Study of drug excipient compatibility by various approaches. UV/Vis spectrophotometer,  Description: Electrospinning machine Compatibility of edaravone and olanzapine with different excipients will be determined.  Interpretation of DSC, UV, Samples of edaravone and olanzapine withdifferent excipient will be prepared by different HPLC, IR. methods i.e. binary mixing, N+1, N-1, electrospinning method. Their compatibility with drug will be detected by storage at different storage conditions and analysis of samples at different time Language Known: intervals by HPLC. By these novel methods drug excipient compatibility study will be done by  English, Hindi, Marathi systematic way.

38 PRAJAPATI AKHILESH KIRTIKUMAR Address: D-103 Aryaman Awas, Opp. Saibaba temple, Ramdevnagar, Satellite, Ahmedabad-380015, Gujarat, India. Contact no.: +91-9727450344 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/akhilesh-prajapati-5979a5192/

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 9.3 CGPA till 2nd semester 2018 - AIR 148 & Qualified  2014-18: Bachelor of Pharmacy from Institute of Pharmacy, Nirma University (IPNU), Gujarat GPAT 2018 - AIR 609 with 8.73 CGPA  Merit based scholarship in B. Pharm awarded by Dissertation: IPNU  Title: Development of Analytical and Bioanalytical Method for Simultaneous assessment of Palonosetron and Cytarabine in a Nano-Formulation Skills:  Description:  Handling of analytical Chemotherapy causes multiple side-effects including Chemotherapy Induced Nausea and instruments Vomiting (CINV). To overcome this side-effect, the study focuses on formulating a nano-  Team management formulation having a combination of a chemotherapeutic (cytarabine) and anti-emetic agent  Organizational skills

(palonosetron). Co-loaded PEGylated nano-formulation is developed to tailor release profile Language Known: of palonosetron and cytarabine. Also, the study involves development and validation of  analytical and bioanalytical for simultaneous assessment of drugs as per recommended English, Hindi, Gujarati guidelines and used for release study and pharmacokinetic study.

LOKESH SHARMA Address: Nagla charandas Phase 2 Noida Gautam buddha nagar Uttar pradesh Contact no.: +91 88 51 33 21 00 E-mail ID: [email protected] LinkedIn Profile: https://linkedin.com/in/bhavin-gayakvad-63711713a

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 8.2CGPA till 2nd semester 2018 & GPAT 2018  2014-18: Bachelor of Pharmacy Ram-eesh institute of vocational and technical education Skills: Greator Noida, affiliated by AKTU University, , Uttar Pradesh with 81 %.  Handling of instruments Dissertation: including HPLC, LCMS,  Title: Development of same-ness approaches for the biosimilars through orthogonal analytical DSC, FT-IR, UV/VIS, TGA, methods using selected marketed formulations. NMR, Bioanalyzer ,GelDoc  Description:  Laboratory techniques such We are trying to develop validated methods on different analytical techniques for as SDS PAGE, Isoelectric establishment of comparability studies of marketed formulations of biosimilars with reference focusing, protein characterization studies product. We will be developing the methods for the assessment of quality of biosimilars available in Indian market. These methods may be adopted by the Indian pharmacopoeia, Language Known: Indian industries can also use these methods for internal development of biosimilars and also  English, Hindi the Indian regulatory bodies may adopt the methods for approval process

39 NIRAJ KUMAR PANDAY Address: Karnataka Boys Hostel, Chokkanahalli Layout, Av Anekal, Karnataka, 560064 Contact no.: +918660013775 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/niraj-kumar-panday-71b39b147

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 Education and Research (NIPER), Ahmedabad with 9.20 CGPA till 2nd semester AIR 187 & Qualified GPAT 2018 AIR 202  2014-18: Bachelor of Pharmacy from Karnataka College of Pharmacy, Bangalore, Rajiv  2nd Topper in B. Pharm Gandhi University of Health Sciences, Karnataka with 83.33% 2014-18  3rd in Mybo quiz Dissertation: Skills:  Title: Physicochemical characterization, bioanalytical method development and validation,  Handling of analytical metabolite profiling and pharmacokinetic study of novel anti-cancer molecule instruments  Description: Novel anticancer molecule of piperazine derivative. During my project work I will be  developing this new molecule to further stage of drug development. Preliminary study includes Interpretation of UV, IR, Mass and NMR data physicochemical characterization. Bioanalytical method will be developed and validated according to USFDA bioanalytical guideline. Once after the proper dose will be decided as per OECD guidelines, Language Known: I will be studying different pharmacokinetics parameters in animals. At the end In vitro and In vivo metabolites will be identified and characterized using LC-MS/MS.  English, Hindi

GONE RAJENDAR REDDY Address: 5-81, Nagarguda, Shabad Mandal, Tallapally, Ranga reddy Dist. Telangana - 509217. Contact no.: +919542985677 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/rajendar-reddy-99b371187 zz

Education: Achievements:  Qualified NIPER JEE  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical 2018 and GPAT 2018 nd Education and Research (NIPER), Ahmedabad with 8.4 CGPA till 2 semester  Won 2nd prize in poster  2014-18: Bachelor of Pharmacy from Malla Reddy College of Pharmacy, Osmania University, presentation-Indo-US Telangana with 75 % international conference

held in our college (MRCP) Dissertation: Skills:  Title: Part-1 Development of analytical approach for determination of comparative pKa for  Good at Handling of HPLC, NCE and Part-2 Development of bioanalytical method and validation for comparative DSC, UV/Vis pharmacokinetic study pf apremilast and its co-crystals spectrophotometer  Description:  Interpreting UV, IR, NMR Developing a novel method to determine the pKa of NCE molecules through online H/D and Mass spectra exchange process by LC-MS with minimal quantity of sample.  Softwares like: Autodock, Apremilast is BCS class IV moiety so it has less solubility and bioavailability. We are going to topspin, Opus

check the bioavailability of different apremilast cocrystals in rat plasma and compare with Language Known: apremilast drug.  English, Hindi, Telugu

40 SUNIL CHHABU RONGATE Address: At-Kawadadara Post office-Sakur Tal-Igatpuri Dist-Nashik,Maharashtra Pin Code- 422502 Contact no.:+918007982261 E-mail ID:[email protected] LinkedIn Profile: https://www.linkedin.com/in/sunil-rongate-a8337b193

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  Qualified NIPER JEE & Education and Research (NIPER), Ahmedabad with 8.3 CGPA till 2nd semester. GPAT in 2018.  2014-18: Bachelor of Pharmacy from SMBT College of Pharmacy, Pune University,  Qualified elementary and Maharashtra with 66.47%. intermediate exam.

Dissertation: Skills:  Title: Development of stability indicating RP-HPLC assay method for Gefitinib and Metformin  Efficient handling experience by QbD approach and characterization of its degradants by LC-MS/MS on instruments like DSC,  Description: UV, HPLC, FT-IR, It has been shown in a number of studies that metformin combined with gefitinib can reduce  Knowledge of interpretation tumor proliferation and colony-forming ability and has significant pro-apoptotic effect against of DSC, HPLC, IR, UV. NSCLC cell lines in general, and against NSCLC cell lines that are resistant to EGFR-TKI as  Software handled like well as it also shows synergistic effect in NSCLC. SIAM on Gefitinib and Metformin was Mendeley, Chemdraw, reported but there was no study were performed on this combination. This study involves Topspin.

development of Stability indicating assay method for quantification of Gefitinib and Metformin Language Known: in presence of their degradants by using QbD approach and Characterization of degradant  products by LC-MS/MS to established molecular structure of degradants. English, Hindi, Marathi

EDAKE SUSHIL SAMADHAN Address: At: Golegaon, Post: Tuljapur, Tal: Deulgaon , Dist: Buldana, Pin Code:443204. Contact no.: +918550986590 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/sushil-edake-0413b1151

Education: Achievements:  2018-20: M. S. (Pharm.) in [Pharmaceutical Analysis] from National Institute of Pharmaceutical  Qualified NIPER JEE & Education and Research (NIPER), Ahmedabad with 8.26 CGPA till 2nd semester. GPAT 2018.  2014-18: Bachelor of Pharmacy from Government college of pharmacy, Amravati Sant Gadge Skills: Baba Amravati University, Maharashtra with 6.88 CGPA.  Handled software’s like Dissertation: Endnote, Topspin,  Title: Development and validation of simultaneous quantitative method for Ranolazine and Mendeley, Chembiodraw. Enalaprilat in rat plasma and their pharmacokinetic application.  Hands on experience of U.V,  Description: HPLC, DSC, FT-IR, LC-MS. Ranolazine inhibit enhanced late INa+ and reverse the Na+ and Ca2+ overload. Enalapril  Interpretation of IR, U.V, NMR. decrease production of Ang II and reduce collagen accumulation in cardiac interstitium and cardiomyocyte hypertrophy. Ranolazine and Enalapril improved LV function and remodeling Language Known: with moderate heart failure. Extending this knowledge, present study aims to develop and  English, Hindi, Marathi validate bioanalytical method for the simultaneous quantitation of Ranolazine and Enalaprilat in rat plasma and will be validated as per US FDA Guidelines. The developed method will be used to establish pharmacokinetic profile of this drug combination.

41 AKHILA PYARAM Address: C-9, BSNL telephone quarters, vinay nagar colony, IS sadan, HYD, Telangana. Contact no.: +91 8374717038 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/akhila-pyaram-53043b175

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 8.7 CGPA till 2nd semester 2018 & GPAT 2018

 2014-18: Bachelor of Pharmacy from UCPSc, KU, Hanamkonda, Warangal, Telangana. State Skills: with 70%.  Have skills in interpretation Dissertation: of UV, IR, and NMR.  Title: Simultaneous quantification method for Metformin and Enzalutamide in rat plasma and  Handling experience with the its application to pharmacokinetic study and plasma protein binding studies instruments like HPLC, UV-  Description: Vis spectrophotometer, Enzalutamide shows it anti-cancer property by interrupting the interaction between androgen DSC, TGA, FT-IR. receptor and DHT and Metformin inhibits enzalutamide-induced EMT in prostate cancer cell  Time management and by targeting TGD-β1/STAT3 and this combination is in clinical trial phase 2 to treat metastatic capability to handle critical situation. castration resistance prostate cancer(mCRPC). So, aim of this study is to develop bioanalytical method to quantify both drugs in rat plasma simultaneously and validate the method according Language Known: to USFDA bioanalytical method validation guidelines and its pharmacokinetic assessment and  English, Telugu, Hindi plasma protein binding studies.

DHRUVISHA JAYESH POKAR Address: 3, Umasmurti, New Maneklal, L.B.S Marg, Ghatkopar(W), Mumbai- 400086 Contact no.: +919820829104 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/dhruvisha-pokar-741a26185

Education: Achievements:  2018-20: M. S. (Pharm.) in department of pharmaceutical analysis from National Institute of  Qualified NIPER JEE and Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.53 CGPA till 2nd GPAT in 2018. semester  Awarded merit-based  2014-18: Bachelor of Pharmacy from Bharati Vidyapeeth College of Pharmacy, Mumbai scholarship in 2nd and 3rd University, Maharashtra with 8.49 CGPA year BPharm by Ratan Tata trust. Dissertation: Skills:  Title: Development and validation of stability indicating RP-HPLC assay method for  Hands on experience of quantitative determination of Venetoclax and characterization of its major degradants by LC- HPLC, FT-IR, U.V, DSC. MS/MS.  Interpretation of UV, IR and  Description: NMR data Venetoclax is a novel, orally bioavailable Bcl-2 family protein inhibitor that is being developed  Software like Topspin, for the treatment of chronic lymphocytic leukemia (CLL) and other hematological malignancies. Mendeley, Chemdraw. It is essential to have information about degradation products as it may affect the safety and efficacy of parent drug. The extensive literature search revealed that there is no SIAM reported Language Known:  for venetoclax. The aim of my study is to develop and validate the SIAM for characterization English, Hindi, Gujarati, of major degradation products by HPLC and LC-MS/MS. Marathi.

42 HARSHADA ANIL BHALERAO Address: Room no.9 Vighnahar row house, Radha-Krushna nagar, Ashok Nagar Satpur, Nashik, Maharashtra-422012 Contact no.: +919075707036 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/harshada-bhalerao-2ab085176

Education: Achievements:  2018-20: M. S. (Pharm.) in [Pharmaceutical Analysis] from National Institute of Pharmaceutical  GPAT and NIPER Education and Research (NIPER), Ahmedabad with 8.36 CGPA till 2nd semester Qualified  2014-18: Bachelor of Pharmacy from N.D.M.V.P Samaj’s college of Pharmacy, Nashik, Savitri-  Qualified Elementary and Bai Phule Pune University, Maharashtra State with 71.08 % intermediate drawing exam Dissertation:  Silver medalist in national  Title: Simultaneous Bioanalytical method development and validation of Neurotransmitters level karate competition by LC-MS/MS(Q-TOF) and its application in animal studies. Skills:  Description:  Handling of analytical Neurotransmitters play an essential role in neuronal chemistry. Various neurotransmitters are Instruments(HPLC,LCMS, involved in various neurological disorders and their up or down regulation leads to disorders  UV-Visible, spectroscopy like Alzheimer’s, Parkinson’s, Stroke, Neuroblastoma and so on. So, quantitation of DSC,FT-IR/ATR) neurotransmitters is important in above cases. My study involves development of a robust LC-  Software skills: MS/MS bioanalytical method for simultaneous detection of 5 neurotransmitters Glutamate, Chembiodraw, MS-Office GABA, Dopamine,5-hydroxy indole 3 acetic acid,2,3 dihydroxy phenyl acetic acid and its validation according to US-FDA guidelines. Language Known:  English, Hindi, Marathi

JAYSHRI KRISHNA DEORE Address: Flat No. 3, Radha-Krisha appt., behind essar petrol pump, Dindori road, Mhasarul, Nashik, Maharashtra 422004 Contact no.:+919130752271 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/jayshri-deore-a8324118b

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  Qualified NIPER JEE & Education and Research (NIPER), Ahmedabad with 8.267 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from NDMVP College of Pharmacy, Nashik, Savitribai Phule  Qualified Elementary and Pune University, Maharashtra with 64.20% intermediate drawing exam Dissertation:  Runner up in cricket in  Title: Impact of particle size on Reverse Engineering using thermal methods INSM 2019  Description: Exploring DSC and HSM techniques for qualitative as well as quantitative estimation of drug Skills: content in a given formulation. Especially, focusing on evaluating the effect of particle size in  Handling of analytical finding out the lower limit with which an API can be estimated with reliable accuracy using instruments and HSM. Laser diffraction will be also used to assess the PSD of API and blend to further validate interpretation of data the findings of thermal methods. We are also expecting that we will be able to find out minimum (HPLC,DSC,UV,Mastersizer, HSM,FTIR/ATR) number of particles need to be counted to arrive at reliable results during reverse engineering studies. Language Known:  English, Hindi, Marathi

43 KOMAL RAMESH BHAMARE Address: Sanskruti Nagar, Nampur Road, Satana,Nashik ,Maharashtra 423301 Contact no.: 9527154020 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/komal-bhamare-b875a7138

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  NIPER JEE 2018 qualified Education and Research (NIPER), Ahmedabad with 8.76 CGPA till 2nd semester  GPAT 2018 - AIR 14  2019-20: PG DIPLOMA in Patent Law from NALSAR University, Hyderabad.  Runner up in cricket in  2014-18: Bachelor of Pharmacy from NDMVP’s College of Pharmacy Nashik, Savitribai Phule INSM 2019

Pune University, Maharashtra with 64.20% Skills: Dissertation:  Proficient in handling of  Title: Compatibility studies of phytosterols with components of Bone cement and it’s in vitro analytical instrument and release study interpretation of HPLC, IR,  Description: UV,LC-MS ,DSC,HSM data.

Bone cements are generally used for fixation of implant to bones but over a period of time, bone cement gets loose and forms gaps in between bone and cement. To resolve this problem Language Known: osteoconductive material such as β -sitosterol and stigmasterol are incorporated in bone  English, Hindi, Marathi cement which will regenerate bone tissue at this interface. Compatibility study of β-sitosterol

and stigmasterol with components of bone cement at different conditions of temperature and humidity will be performed by DSC, HPLC. Preparation and characterization of bone cement.

NANCY GOYAL Address: House no.1283, Urban Estate, Phase 2, Patiala Contact no.: +91 623 973 8103 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/nancy-goyal-b66269193

Education: Achievements:  2018-20: 2018-20: M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of  Qualified NIPER JEE Pharmaceutical Education and Research (NIPER), Ahmedabad with 8.9 CGPA till 2nd 2018 & GPAT 2018 Semester

 2014-18: Bachelor of Pharmacy from Punjabi University, Patiala, Punjab with 77% Skills: Dissertation:  Handling of analytical  Title: LC, LC-MS, QTOF AND NMR studies on stress degradation behaviour of selected drugs instruments used in cancer therapy  Interpretation of NMR, Mass  Description:  Ability to work in team Pamidronate is an Amino-Bisphosphonate used to strengthen bone in Paget's disease. It will and individually as well. be considered for 31P quantitative NMR due to limitations associated with existing methods. Eg. HPLC-RI (Refractive Index) method. Language Known: Ruxolitinib is JAK1/2 inhibitor effective against myeloproliferative. A simple and accurate SIAM  English, Hindi, Punjabi will be developed. Major degradation products will be characterized by LC-MS/MS. The possible degradation mechanism and respective molecular structures of degradation products will be proposed for both the drugs.

44 PRERANA SANDIP GANGAWANE Address: Flat no. A1, Shivgaya complex, gajanan colony, Chhatrapati Nagar, Garkheda Parisar, Aurangabad Contact no.: 91 8830045406 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/prerana-gangawane-b439b9137

Education: Achievements:  2018-20 M. S. (Pharm.) in Pharmaceutical Analysis from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 7.48 CGPA till 2nd semester 2018 & Qualified GPAT  2014-18: Bachelor of Pharmacy from Government College of Pharmacy, Dr. Babasaheb 2018 Ambedkar University, Maharashtra with 69.47%

Dissertation: Skills:  Title: Development of an analytical approach for correlating CQA, CPP and CMA of PLGA for  Analytical Instrument achieving the desirable QTPP of control release formulation handling and its  Description: interpretation (DSC, NMR, Different batches of synthesis will be carried out with different CPP and CMA using its HPLC, TGA, FTIR)  Communication monomer namely Lactic Acid and Glycolic Acid followed by its Analysis using techniques like NMR, DSC, Rheometer, GPC for the measurement of the CQA (ratio of monomer, Glass Language Known: transition temp, Viscosity, Mol. weight) and also dissolution profile will be evaluated as a QTPP  English, Hindi, Marathi in the CRS against CQA.

RAMPILLA PUSPA KANAKA MADHURI Address: D.No: 27-54(77), Upparabavi street,Nagasai Baba temple road, Vijayawada (urban), Kamakotinagar, Krishna district, Andhra Pradesh- 520012 Contact no.: +919505058487 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/madhuri-rampilla-238721144

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutical analysis from National Institute of Pharmaceutical  Qualified NIPER JEE Education and Research (NIPER), Ahmedabad with 8.8 CGPA till 2nd semester. 2018 - AIR 258 &  2014-18: Bachelor of Pharmacy from KVSR Siddhartha college of Pharmaceutical sciences, Qualified GPAT 2018. Krishna University, Andhra Pradesh with 9.23 CGPA.  1st prize in poster presentation- Pharmacognosy and Dissertation: herbal formulation  Title: Establishment of a bioanalytical method for simultaneous quantitation of edaravone- Skills: caffeine and its pharmacokinetic safety profiling.  Handling of analytical  Description: instruments and Edaravone and caffeine are having potent endogenous antioxidant activity and ROS interpretation of data. scavenging action, as this combination has neuroprotective role in Parkinson’s disease. The  Time management, present study mainly focuses on the development of bioanalytical method for simultaneous Adaptability, Team work and quantification of edaravone and caffeine in rat plasma, validation of the method following Self-Motivation United State Food and Drug Administration (USFDA) bioanalytical guideline and its application Language Known: in evaluating the in vivo pharmacokinetics in rat.  English, Hindi, Telugu

45 Department Of

Pharmacology & Toxicology

Departmental Expertise:  Pharmacology & Toxicology lab focuses on Cerebral ischemia, Parkinson’s disease and Cancer  Deciphering the molecular mechanism of stem-cell-mediated neuroprotection post ischemic stroke.  Neuroendocrine regulation and exploring the cross talk of mitochondria and endoplasmic reticulum in stroke  Employing small animal stroke models (MCAo, cardiac arrest and global ischemia) for preclinical studies.  Stem cell engineering and nanoparticle based targeted drug delivery to the brain.  Investigating the role of neuroinflammation in aggregation and transfer of toxic alpha synuclein in chronic treatment mouse model of Parkinson’s disease.  Development of progressive mouse model of Parkinson’s disease evolving from either olfactory bulb or enteric nervous system.  Development and identification of neuroprotective therapy which may halt or reverse the progression of Parkinson’s disease pathology.  Identifying the components in coffee and tobacco which makes people less susceptible to develop Parkinson’s disease.  Exploring the Pyruvate kinase M2 (PKM2) interacting proteins and to therapeutically target the enzyme using PKM2 activators in breast and oral cancer 46 SAKEEL AHMED Address: Naharika, Teh: Ferozepur jhirka, Distt: Nuh, Haryana, India. 122108 Contact no.: +919991564667 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/sakeel-ahmed-68705a143/

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified NIPER JEE Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.14 CGPA till 2nd 2018 & GPAT 2018. semester  CUCET 2018 with 53.4%.  2014-18: Bachelor of Pharmacy from Pharmacy college, RUHS, Rajasthan with 79.69  University 2nd Rank in B. % Pharmacy Part II. Skills: Dissertation:  Professional Software like:  Title: Exploring the anti-inflammatory activity of tobacco components in brain via α-7 nicotinic Chembiodraw, GraphPad acetylcholine receptor using chronic rotenone mouse model of Parkinson’s disease. prism, Mnova, ImageJ,  Description: Epidemiological evidence suggests the inverse association of smoking and Mendeley. Parkinson’s disease. In smoking, there are approximately 4000 compounds in which the most  Handling of Instruments: abundant is Nicotine and Anabasine. These two compounds are reported to act on the α-7 western blotting, nAChR and give their anti-inflammatory effect. By Nicotine and Anabasine we want to see the immunohistochemistry etc. effect of these two compounds on the neuroinflammation and α-synuclein aggregation via  Small Animal Handling. activation of α-7 nAChR located on the neuroglia. So, we believe that, Nicotine and Anabasine will bind to the α-7 nAChR on neuroglia and decrease neuroinflammation as well as α-synuclein Language Known:  aggregation ultimately delay the progression of Parkinson’s disease (PD). English, Hindi, Urdu

ANKAN SARKAR Address: Ashok kumar sarkar c/o H.N.sarkar, sukanta pally, near shib shakti kalibari, gate bazar, siliguri, West Bengal- 734005 Contact no.: +917405373650 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/ankan-sarkar-884a31148

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified NIPER JEE Pharmaceutical Education and Research (NIPER), Ahmedabad with 8.94 CGPA till 2nd 2018 & GPAT 2018 semester Skills:  2014-18: Bachelor of Pharmacy from Parul institute of Pharmacy, Gujarat Technological  Optimistic University, Gujarat with 78%/8.30.  Persevering

Dissertation: Language Known:  Title: Neuroprotective role of Apelin-13 in Post stroke depression  English  Description: Focal cerebral ischemia leads to glutamate excitotoxicity cause change in the  Hindi physiological ratio of TrkB due to calpain, Matrix Metalloproteinase, γ-secretase cleavage.  Bengali Ectodomains formed by the cleavage results in inhibition of (BDNF). Inhibition of BDNF leads to activation of phosphorylated FOXO by AKT leading to apoptosis, decrease in neurogenesis which triggers depressive symptoms and cause post-stroke depression. In this study, we will administer apelin-13 via intracerebroventricular route after MCAo. We will study the behavioral parameters and check the expression of BDNF and FOXO by western blotting. We will try to determine whether the administration of Apelin-13 will ameliorate PSD and its symptoms in ischemic rats.

47 NIRAJ NIVAS TADASARE Address: 156/3,Savali, Rajgruha housing society, Plot No.7,Vishrambag,, Mahrashtra-416415 Contact no.: +918408011996 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/niraj-tadasare-a62427162

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified NIPER JEE 2018 Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.37 CGPA till 2nd and GPAT 2018 semester  SPPU 9th rank (B. Pharm)  2014-18: Bachelor of Pharmacy from Maharashtra Institute of Pharmacy, Savitribai Phule Pune  Lean Six Sigma White belt University (SPPU), Maharashtra with 76.20 % Skills: Dissertation:  Skilled in laboratory rodent  Title: Exploring the anti-inflammatory effect of tobacco components via enteric α7 nicotinic handling, protein acetylcholine receptor using a chronic rotenone mouse model of Parkinson's disease. characterization,  Description: Parkinson’s Disease (PD) is the age-related neurodegenerative disorder. immunostaining According to Braak’s hypothesis pathology starts from the gut. Alpha synuclein aggregation is  Hands on experience of the major hallmark of PD. Inflammation is an important trigger of synuclein aggregation. So, we chromatographic techniques are targeting inflammation in gastrointestinal tract. Smoking has evidences of inverse relation  Software like Chembiodraw, with the PD. As Nicotine and Anabasine are the major components of any tobacco product. We Biorender, Graph Pad Prism, are working on anti-inflammatory effect of both components on enteric alpha 7 nicotinic ImageJ, MestReNova LITE, acetylcholine receptor. Reduced inflammation through alpha 7 acetylcholine receptor may Mendeley decrease the alpha synuclein aggregation. This may decrease the disease progression if it is Language Known: early detected.  English, Hindi, Marathi

SWAPNIL RIJANLAL RAUT Address: J/202 Vanashree Panchavati Khadakpada Road Kalyan (W), Maharashtra-421301. Contact no.: +917738600138 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/swapnil-r-a144a593

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified NIPER JEE 2018 Pharmaceutical Education and Research (NIPER), Ahmedabad with 7.40 CGPA till 2nd & GPAT 2018 semester  Secured First position in  2014-18: Bachelor of Pharmacy from Konkan Gyanpeeth Rahul Dharkar College of Pharmacy, poster presentation ICMR Mumbai University, Maharashtra with 7.23 CGPA. sponsored National Seminar on 14th Jan 2017 Dissertation:  Title: Deciphering the role of Statin in altering mitochondrial function in Ischemic Stroke. Skills:  Description: During ischemic insult, there is the generation of oxidative stress and  Team worker inflammation via inflammasome activation which insidiously damage the cerebral neurons,  Adaptable leading to various complications. Past studies have shown that when oxidized mitochondrial  Perseverance DNA gets exposure of cardiolipin, it leads to inflammasome activation resulting in caspase 1 activation and maturation of proinflammatory cytokines. We hypothesize that Simvastatin may interact and regulate the cardiolipin level resulting in inhibition of inflammasome which will lead Language Known:  to inhibition of Caspase 1 activation and maturation of proinflammatory cytokine. English, Hindi, Marathi

48 SATWIK MAKARAND DASTANE Address: Plot no. 82, Shreenidhi, Nisarg colony, Khode nagar, Nashik-422006 Contact no.: +91 96899 95519 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/satwik-dastane-2980b3178

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Passed elementary and Pharmaceutical Education and Research (NIPER), Ahmedabad with 7.54 CGPA till 2nd intermediate drawing semester exams  2014-18: Bachelor of Pharmacy from Sir Dr. M. S. Gosavi College of Pharmaceutical Education  Passed Maharashtra and Research, Savitribai Phule Pune University, Maharashtra (68.9%) talent search examination Skills: Dissertation:  Laboratory animal handling  Title: Effect of Boronic acid derivative on chemically induced oral carcinoma in mice via and dosing, western blotting, activation of Pyruvate Kinase M2. biochemical assays,  Description: Metabolic reprogramming is considered as one of the hallmarks of cancer. In the sectioning and staining, cancerous tissue there is a marked shift in glycolytic pathway, that it shows glycolysis even in retro-orbital plexus blood the presence of oxygen. In normal cells, PKM2 tetramer is expressed which catalyses the collection conversion of phosphoenolpyruvate (PEP) to pyruvate and ATP. But, in cancer cells alteration  Cryostat, UV multimode in the expression of PKM2 is victimized because of more expression of its dimeric form which reader. is having lesser affinity to its substrate. In lieu, it translocates to nucleus and increases the  ChemBioDraw, EndNote, expression of various transcriptional factors responsible for metastasis and cell proliferation. Mendeley. So, we are investigating the effect of Boronic acid derivative which activates PKM2 to its Language Known: tetrameric form and its effect on oral carcinoma.  English, Hindi, Marathi, Urdu

BIRVA VIPULKULMAR SHAH Address: A-304 Chinmay Towers,Opp Highland Park Hotel, N/R Subhash Chowk, Memnagar,Ahmedabad,Gujarat Contact no.: +917874333324 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/birva-shah-8b4aa4184

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Secured 1st position in Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.60 CGPA till 2nd Pharma Quiz in National semester level event - GTU  2014-18: Bachelor of Pharmacy from LJ Institute of Pharmacy, Gujarat Technological CENTRAL TECHFEST. University, Gujarat with 8.80 CGPA Skills: Dissertation:  Handling of UV spectroscopy, Gel doc,  Title: Exacerbation of Ischemic Stroke Pathology in Chronic kidney disease: Involvement of Cryostat, Microtome Mitochondrial Dysfunction.  In vivo studies, Western  Description: Stroke is the major cause of death and disability worldwide. Renal impairment Blotting, Biochemical Assays has been associated with poor neurological deficit with functional declination and higher  Active listener,Managerial morbidity. Excessive mitochondrial fission leads to increase in fragmentation of mitochondria skills, Communication and results in dysfunction of mitochondria. Drp1 is the master protein responsible for mitochondrial fission. Here, we hypothesize that mitochondrial dysfunction may play a role in Language Known: the exacerbation of ischemic stroke pathology due to CKD.  English, Gujrati, Hindi

49 CHAITALI CHANDRAKANT SHAHA Address: 7/157, Satyam Apartment,near Ranka hospital, Mukundnagar,Pune-411037 Contact no.: +919028634191 E-mail ID: [email protected] LinkedIn Profile: http://www.linkedin.com/in/chaitali-shaha-817870126

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified NIPER JEE Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.40 CGPA till 2nd 2018 & GPAT 2018 semester Skills:  2014-18: Bachelor of Pharmacy from All India Shri Shivaji Memorial society’s college of  Laboratory exposure for pharmacy, Savitribai Phule Pune University, Maharashtra with 75% small animal handling,

protein characterization, Dissertation: molecular techniques  Title: Effect of Boronic acid derivative on chemically induced oral carcinoma in mice via  Good exposure of scientific activation of Pyruvate Kinase M2. retrieval tools and various  Description: Parkinson's disease (PD) is an age-related, progressive, multisystem softwares neurodegenerative disorder resulting in significant morbidity and mortality. Current treatment  Handling of Cell Culture and is centered upon dopamine replacement to alleviate the symptoms. There are still insisting related instruments needs to develop disease modifying drug for treatment of Parkinson’s disease. Therefore, we  Hands on experience of will be screening the newly synthesized compounds for its selective MAO-B inhibitory and histological techniques neuroprotective activities by in silico methods using molecular docking, in vitro studies using neuronal cell lines (SH-SY5Y and PC 12) and in vivo studies using acute rotenone induced Language Known: mice model of Parkinson’s disease. From these studies we may get a novel, therapeutic MAO-  English, Hindi, Marathi, B inhibitor as a disease modifying treatment to relieve Parkinsonism. Gujarati

FALGUNI BAIDYA Address: VILL- HAPANIA, P.O- NAGARUKHRA, P.S- HARINGHATA, DIST- NADIA, STATE - WEST BENGAL. Contact no.: +918906237001 E-mail ID: [email protected] LinkedIn Profile: http://www.linkedin.com/in/falguni-baidya-750761192

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad with 8.8 CGPA till 2nd semester  Qualified CUCET- 2018  2014-18: Bachelor of Pharmacy from NSHM knowledge campus, Kolkata. Maulana Abul  BITS PILANI M. Kalam Azad University of Technology, West Bengal with 8.49 CGPA pharm admission test Dissertation: 2018 Skills:  Title: Investigating the role of Inosine on inflammasome signaling in animal model of ischemic  Handling of small laboratory stroke. animals.  Description: At the early stage of cerebral ischemia activation of immune response causes  Small animal surgery (MCAo, invigoration of inflammasome signaling that leads to brain edema and pyroptosis. Inosine, a cannulation, ovariectomy) naturally occurring purine nucleoside, has shown to promote axonal collateral growth and this  Western blot, Biochemical plasticity improves recovery in ischemic stroke model. In our study, we will check whether i.p estimation (BCA, MDA, Nitrite, GSH, Catalase) administration of inosine inhibits the inflammasome activation & it’s oligomerization in MCAo model, thus prevent neuronal cell death during cerebral ischemia. Language Known:  English, Bengali, Hindi

50 JASWINDER KAUR Address: Vill. Kuthar Kalan, P.O,Distt.,Teh. Una, Himachal Pradesh 174303 Contact no.: +9188946-49237 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/jaswinder-kaur-348177193

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified NIPER JEE & Pharmaceutical Education and Research (NIPER), Ahmedabad with 8.50 CGPA till 2nd GPAT 2018 semester  2014-18: Bachelor of Pharmacy from KC Institute of Pharmaceutical Sciences, Himachal Skills: Pradesh Technical University, Himachal Pradesh with 73.9%  Hand on experience in Dissertation: handling small animals and  Title: Development of progressive intranasal mouse model of Parkinson’s Disease and laboratory techniques. validation through associated Neurodegenerative markers.  Experience in formulation  Description: The project aims to develop a progressive and chronic intranasal mouse model and development. of Parkinson’s disease which will simulate the clinical pathological condition of the disease. To  Good interpersonal and achieve this, we will be inducing aggregation of α-Syn in olfactory bulb upon intranasal communication skills. administration of rotenone mucoadhesive microemulsion, and from there pathology will  disseminate to the other part of brain in chronological manner. Validation of model will be done Scientific software handling by assessment of neurodegenerative marker such as phosphorylated α-Syn, Dopamine Transporter (DAT) and tyrosine hydroxylase (TH). Language Known:  English, Hindi, Punjabi

RITU MITESH SONI Address: B-102 Sukirti Garden, opposite super society, behind ramdevnagar, satellite, Ahmedabad, Gujarat- 380015 Contact no.: +91 9724197239 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/ritu-soni-52372a189

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  1st prize in Pharma quiz Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.52 CGPA till 2nd and Pharma recipe in semester Central GTU Techfest.  2014-18: Bachelor of Pharmacy from LJ Institute of Pharmacy, Gujarat Technological  Gld medalist throughout University, Gujarat with 9.05 CGPA B.Pharm in LJIP. Dissertation: Skills:  Handling of small laboratory  Title: Exploring Neuroprotective role of chlorogenic acid mediated by GLP1 secretion and animals (mice and rats) synergistic effect of chlorogenic acid and caffeine on rotenone induced mouse model of  Molecular techniques Parkinson’s disease. including western blot,  Description: Parkinson’s disease is an age-related disorder which leads to dopamine deficiency biochemical assays (BCA, and motor impairment. Alpha synuclein is a major hallmark of this PD pathology. Recent studies GSH, MDA, Nitrite) have reported that intake of coffee is associated with decreased risk of PD. Thus, we aim to determine effect of coffee constituent chlorogenic acid against alpha-synuclein aggregation mediated Language Known: by GLP1 release in Chronic rotenone mouse model of Parkinson’s disease.  English, Hindi, Gujarati

51 UPASNA SINGH Address: Village: Tarri, Post: Patewa, Teh: Abhanpur, Dist: Raipur (Chhattisgarh) India. 493885 Contact no.: +919098393371 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/upasna-singh-8aa349175

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified NIPER JEE Pharmaceutical Education and Research (NIPER), Ahmedabad with 8.34 CGPA till 2nd 2018 - AIR 1508 & semester Qualified GPAT 2018 -  2014-18: Bachelor of Pharmacy from Pt Ravishankar Shukla university, Raipur (Chhattisgarh) AIR 1135 with 75 % Skills:

Dissertation:  Hard working  Title: Deciphering the role of statin in neurogenesis after focal cerebral ischemia.  Punctual  Description: Ischemic stroke is devastating and a major cause of mortality. Ischemic cascade  Responsible is a complex series of neurochemical processes includes excitotoxicity, oxidative stress, BBB  Co-operative dysfunction and finally cell death. PI3K/Akt pathway is involved in cell survival and neurogenesis. In ischemic stroke deprivation of neurotropic factor BDNF results in deactivation Language Known: of PI3K/Akt pathway, which will lead to decreased neurogenesis. Statins are HMG-CoA  English, Hindi, Chhattisgarhi reductase inhibitor with pleiotropic effects. In this study, we will check the effect of simvastatin on Akt pathway mediated neurogenesis.

KALE RUHI ARVIND Address: B/5, Ravideep Soc., Near Sarvesh hall, Tilak road, Dombivili east-421201. Contact no.: +919970737172 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/ruhi-black-830795103/

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified NIPER JEE Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.12 CGPA till 2nd 2018 - AIR 189 & Qualified semester GPAT 2018 - AIR 368  2014-18: Bachelor of Pharmacy from K. M. Kundnani College of Pharmacy, Mumbai University,  PharmaRecipe Maharashtra with 7.41 CGPA competition of PharmaVision at RPCP, Dissertation: CHARUSAT University

 Title: Exploring the Role of Caffeine and Caffeine Combined with Chlorogenic Acid on Enteric Nervous System in Rotenone Induced Mouse Model of Parkinson’s Disease Skills:  Description: Parkinson’s disease (PD) is aging neurodegenerative disorder characterized by  Laboratory animal degeneration dopaminergic neuron in SNpc.The hallmark of this disease is the presence of α- handling,western synuclein aggregates. Targeting and identifying the non-motor symptoms is of great blotting.cryosectioning ,IHC. importance as they are seen long before the disease even actually starts. Braak demonstrated  the transfer of α-synuclein from the gut to the CNS. The gut neuronal degeneration is the ChemBioDraw,ImageJ, reason for problems of gut motility such as constipation. There are also evidences of reduced GraphPad Prism. risk of PD in coffee drinkers. Thus, there is a great scope that caffeine might have a role to play by acting at gut level and remedying the non-motor symptoms. Language Known:  English, Hindi, Marathi

52 MARIYA BOHRA Address : Lucky General Store, Tehsil Road, Nathdwara, Rajsamanand,(RAJ). Contact no.: +917737778651 E-mail ID : [email protected] LinkedIn Profile: http://www.linkedin.com/in/mariya-bohra-b16759192

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of Qualified NIPER JEE 2018 & Pharmaceutical Education and Research (NIPER), Ahmedabad with 8.94 CGPA till 2nd GPAT 2018 semester Skills:  2014-18: Bachelor of Pharmacy from Bhupal Nobles’ College of Pharmacy, Udaipur affiliated  In vivo studies, Western to Rajasthan University of Health Sciences with 76.33% Blotting, Biochemical Dissertation: Assays  Title: Investigating the role of inosine in cerebral ischemia via PI3K-AKT Pathway.  UV spectrophotometer,  Description: The project aims to find out the molecular mechanism of inosine in treating Cryostat and Microtome. cerebral ischemia. Ischemia occurs due to occlusion of an artery which results in lack of glucose Prism-GraphPad, GelDoc and blood supply to the brain, culminates in neuronal death. We hypothesise that inosine via and MS office. activation of TRAF-2 will lead to ubiquitination of AKT which further result in its phosphorylation. Language Known: Once AKT is phosphorylated it activate mTOR signalling which stimulates transcription factors  English, Hindi, Gujarati and ultimately progress to cell survival.

PRIYA RAOSAHEB JAGTAP Address: At post Tamaswadi,Jagtap Complex,Tal-Newasa Dist-Ahmednagar pin code:414602 Contact no.: +917387109257 E-mail ID: priyajagtap57gmail.com LinkedIn Profile: https://www.linkedin.com/in/priya-jagtap-11784918a

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  Qualified GPAT and Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.30 CGPA till 2nd NIPER. semester  2014-18: Bachelor of Pharmacy from Modern College of Pharmacy, Pune University, Skills: Maharashtra with 77.66 %  Laboratory exposure for small animal handling, Dissertation: protein characterization,  Title: Exploring the effect of endoplasmic reticulum stress in exacerbation of stroke molecular techniques pathology in chronic kidney disease.  Good exposure of scientific  Description: CKD is now known as an established risk factor for cardiovascular diseases. retrieval tools and various Stroke is a major player of cardiovascular disease and has deep two-way relationships with software’s CKD. CKD is an evident risk factor for stroke, but the magnitude of increased risk and molecular pathway unclear. The link between CKD and stroke has attracted scientist to Language Known: explore more. We aimed at quantifying the changes that takes place in CKD induced stroke  English, Hindi, Marathi model by endoplasmic reticulum stress pathway leading to altered apoptosis.

53 SIDDHI VIVEK RAKSHE Address: A/202 Paulomi Apartment, Veer Savarkar road, Teen Petrol Pump , Thane west , Maharashtra-400602 Contact no.: +919892772337 E-mail ID: [email protected] LinkedIn Profile: http://linkedin.com/in/siddhi-rakshe-5a27b7134

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmacology and Toxicology from National Institute of  GPAT and NIPER Pharmaceutical Education and Research (NIPER), Ahmedabad with 9.06 CGPA till 2nd Qualified. semester  Finalist for 4th  2014-18: Bachelor of Pharmacy from Oriental College of Pharmacy, Mumbai University, IBRO/APRC Chandigarh Maharashtra with 7.93 CGPA Neuroscience School Dissertation: 2019.  Title: Development of Intranasal Mouse Model of Parkinson’s Disease and its Validation via Skills: presence of phosphorylated Alpha synuclein and Neuroinflammatory Markers.  Analytical Instrument  Parkinson’s disease (PD) is prominently characterized by loss of dopaminergic Description: handling (UV-Spectroscopy, neurons in the Substantia Nigra (SNpc) & presence of Lewy bodies (aggregated ɑ- syn) in the Zeta Sizer, Texture Midbrain. Epidemiological studies suggest a correlation between exposure to environmental toxin & an increased risk of developing PD, especially exposure with the pesticides inhibiting Analyzer). mitochondrial complex I (e.g. rotenone). Braak et al, 2003 suggested that, upon exposure to  Small animal handling, these toxins via inhalation or ingestion, leads to formation of Lewy bodies which progresses Dosing and Behavioral following a stereotypical pattern, starting from olfactory bulbs (OB) & then spreading to the Testing. interconnected brain regions. Researchers have intranasally administered rotenone &  In Vivo techniques (blotting, developed an acute model of PD, but we consider that pathological changes following tissue Staining, Biochemical environmental insults contribute to the initiation of protein aggregation in the olfactory bulb, assays). which later disseminates to other brain regions in a slow & prion-like manner. In this present study, our aim is to develop a progressive intranasal rotenone model of PD using low dose Language Known: nasoretentive rotenone microemulsion, which will act locally on olfactory bulbs rather than  English, Hindi, Marathi, systemically. This may mimic the clinical pathological progression of PD. The validation of the Learning German model will be done via behavioral studies for olfactory dysfunction, motor and memory impairment, presence of phosphorylated ɑ- syn & neuroinflammatory markers.

54

Department Of

Pharmaceutics

Departmental Expertise:  Microemulsion, Nanoemulsion and Nanocrystals for nose to brain delivery of drug  Application of Quality by Design (QbD) in formulation development and optimization of pharmaceutical formulations  Physical characterization of pharmaceuticals using Particle size, Surface zeta potential, Rheology, thermal analysis, and imaging techniques  Solubility enhancement using nanoparticulate approach, electospraying techniques, nanocrystallization, and co-crystallization and their characterization studies  Lipidic nanoformulations and their role in targeting brain, posterior segment of eye, psoriasis etc.

55 TEJAS AVINASH CHAVAN Address: Vasant Vihar, Ozar(MIG), Taluka Niphad, District Nashik, Maharashtra - 422207 Contact no.: +918379899510 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/tejas-chavan-230462189

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualifies NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 8.83 CGPA till 2nd semester Qualified GPAT 2018

 2019-20: PG diploma in Patent Law (Distance learning) from NALSAR university of Skills: Law Hyderabad  Well versed with Electrospinning,  2014-18: Bachelor of Pharmacy from NDMVP College of Pharmacy Nashik, Rotary evaporator, Tablet Savtribai Phule Pune University, Maharashtra with 65.16% compression, Rheometer, HPH, Dissertation: Zetasizer, 3D printer, UV, HPLC,  Title: Development of non-cell, Lipid-polymer based in vitro model for prediction of DSC, FTIR. Permeability through Corneal epithelium  Description: The major obstacle for drug permeability through eye is cornea. Language Known: Currently used ex vivo and in vitro cell culture methods have several disadvantages  English, Hindi, Marathi such as methods are costlier and require number of animals to be sacrificed, etc. Here we aim to prepare a non-cell-based model that can mimic two major barriers of cornea that are corneal epithelium and stroma for study of permeability of various active pharmaceutical ingredients (APIs) and drug formulations.

DEVENDRA KUPARAM CHOUDHARY Address: Shree Ganesh Store, Shop no.6, B-wing, Rameez Baug, Rashid Compound, Kausa Mumbra, Thane. Maharashtra -400612 Contact no.: +919619144172 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/devendra-choudhary-70058715a

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 7.46 CGPA till 2nd semester Qualified GPAT 2018  2014-18: Bachelor of Pharmacy from Dr. L. H. Hiranandani College of Pharmacy,  Secured 2nd position in paper Mumbai University, Maharashtra with 7.67 CGPA presentation at Rx Melange 2018  Secured 1st position in poster Dissertation: presentation at Pharmazest 2017  Title: Effect of Processing Parameters on Reverse Engineering Studies. Skills:  Description: To find out the exact process which is used for the tablet preparation  Handling of equipment’s for (wet granulation, dry granulation or direct compression) by analyzing the surface formulation development and their fracture of tablet by using Scanning Electron Microscope (SEM) in order to develop characterization a generic product in faster and more economical way.  Efficient knowledge of software like Minitab, Design Expert, Endnote, Chembiodraw, MS office, Prism, Graphpad

Language Known:  English, Hindi, Marathi, Marwari

56 GAURAV UTTAMRAO SANAP Address: Plot no.6 ‘Nath Krupa Nivas’, Rajeshri shahu nagar, near sara vrundavan, Bajaj Nagar, Aurangabad, Maharashtra 431136 Contact no.: +918888780021 E-mail ID: [email protected] https://www.linkedin.com/in/gaurav-sanap-8124b4a3 LinkedIn Profile:

Education: Achievements:  2018-20: M. S. (Pharm) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE & GPAT Education and Research (NIPER), Ahmedabad with 8.1 CGPA till 2nd semester 2018  2014-18: Bachelor of Pharmacy from NDMVP College of Pharmacy, Savitribai Phule Pune  Winner of Poster presentation University, Maharashtra with 63 % held at MET Institute, Nasik Dissertation: Skills:  Title: Co- Delivery of Topical Formulation of Apremilast with Vitamin E and Its  Hands on experience of Implication in Psoriatic Arthritis formulation equipment like  Description: Among various routes of administration, topical route is the most preferred optical microscopy, HPLC, UV, and applicable route for drug delivery. Oral administration of Apremilast for Psoriasis and tablet compression machine, psoriatic arthritis shows several systemic side effects such as GIT irritation, headache, tablet coater. abdominal pain etc. thus limiting its use. Thus, formulating the liquid crystalline gel of  Softwares like Chemdraw, apremilast in combination with Vitamin E will not only reduce the systemic side effects Mendeley & MS Office. associated with the oral administration of the drug but also offer enhanced permeability across keratinous barrier. Language Known:  English, Hindi, Marathi

HANMANT DNYANOBA GOYKAR Address: A/P.Gholeshwar, Taluka- Jath, District- Sangli, State- Maharashtra Pin code - 416404 Contact no.: +918600292437 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/hanmant-goykar-70b253177/

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 Education and Research (NIPER), Ahmedabad with 7.9 CGPA till 2nd semester. & GPAT 2018

 2014-18: Bachelor of Pharmacy from Appasaheb Birnale College of pharmacy, Sangli, Skills: Shivaji University Kolhapur, State Maharashtra with 68.20 %  Handling of equipment’s for Dissertation: formulation development and  Title: Crystal engineering as an approach to improve the solubility and dissolution rate their characterization of poorly water-soluble drug.  Efficient knowledge of software  Description: Designing a formulation of poorly soluble drugs face typical problems like like Design Expert, Minitab, too low oral bioavailability and due to their very low saturation solubility and dissolution Endnote, Chembiodraw, MS rate. However, limitations of the existing techniques, warrants the need for new solid forms office, Prism, Graphpad of drug with desirable solid-state property. In current proposal we are planning to formulate a cocrystal of drugs and various coformers by various methods like solid state grinding, Language Known: liquid assisted grinding and electrospraying. These prepared cocrystals will be  English, Hindi, Marathi characterize for various physiochemical attributes along with its solubility and dissolution rates. It will be interesting to study how such cocrystals enhance the solubility and produce controlled release of drug and may emerge as potential solid form for drugs with solubility and release problems.

57 SURAJ RAMVILASH KANNAUJIA Address: Village- Khadicha Post- Dargah District-Mau U.P 276306 Contact no.: +918417096365 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/suraj-kannaujia-88754a186

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 6.8%CGPA till 2nd semester. GPAT 2018  2014-18: Bachelor of Pharmacy from Pranveer Singh institute of technology Kanpur, Skills: UPTU Lucknow, U.P with 78.2%.  FTIR(Bruker) Dissertation:  UV-visible (UV-1800 Shimadzu)  Title: Comparative Evaluation of different Solubility Enhancement Techniques on  Zetasizer(Nano-ZS) Dissolution performance “A Case Study using Olanzapine as Model drug”.  Dissolution apparats USP II and  Description: More than 40% of new chemical entities developed in pharmaceutical IV industries which are practical insoluble in water thus here I am going to technique used  Mastersizer 3000 nanocrystals and solid dispersion preparation and used for enhancing the oral bioavailability then convert into solid dosage form IR tablets and study of precipitation Language Known: during the dissolution studies In-vitro condition. To determine the which formulation is  English, Hindi, Marathi precipitating first out during dissolution studies In-vitro condition.

TUKARAM RAM KARANWAD Address: Triveni nagar, At.post. Kingaon, Tq. Ahmedpur, Dist. Latur, Maharashtra-413523. Contact no.: +918308088208 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/tukaram-karanwad-421b9216a/

Education: Achievements:  2018-20: M. S. (Pharm.) in pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 6.67 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from school of pharmacy, S.R.T.M.U. Nanded,  Securing 1st position in Maharashtra with 6.57 CGPA national level seminar Dissertation: Skills:  Title: Effect of process parameters on study of drug excipients interaction  Efficient Instrument handling like  Description: The stability of formulation depends upon the compatibility of the active FTIR, DSC, HSM, Tablet component with the other ingredients in a mixture. Unless incompatibility is glaringly punching machine, RMG, UV, evident it is necessary to carry out stability study that usually requires weeks or months. HPLC, HPH, Malvern zetasizer, Utilizing DSC, it is possible to obtain significant data rapidly. Enthalpy changes obtained Dissolution apparatus USP I, II from DSC can be successfully used for estimation of stability and compatibility. To and IV determine how far DSC can be relied to accurately predict compatibility issues, in current  Efficient knowledge of software proposal, olanzapine is taken as model drug for the study. Depending upon marketed like Design Expert, Minitab, formulation a compressive list of excipients will be charged for stability studies as well as Endnote, Chembiodraw, MS for DSC analysis. Methods like, solvent evaporation, physical admixture, and slugging will office, Prism, Graphpad be employed for sample preparation to predict the effect of processing condition. On the Language Known: basis of comparative study between DSC and stability studies with different excipients,  English, Hindi, Marathi the excipients will be ranked in decreasing order of stability on the basis of enthalpy.

58 VEDANT PRAKASH GADEKAR Address: At post Ukkalgaon, Shrirampur, Ahmednagar, Maharshtra-413715 Contact no.: +917755995080 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/vedant-gadekar-b5004a184

Education: Achievements:  2018-20: M. S. (Pharm.) in [Branch] from National Institute of Pharmaceutical Education  NIPER JEE 2018 and Research (NIPER), Ahmedabad with 7.51 CGPA till 2nd semester  Qualified GPAT 2018  2019-20: PG Diploma in Patent law from NALSAR university of Law, Hyderabad  State level Volleyball player

 2014-18: Bachelor of Pharmacy from NDMVP College of Pharmacy, Savitribai Phule Pune University, Maharashtra with 63.7 % Skills:  Proficient in HSM, optical Dissertation: microscopy, Tablet compression  Title: Spherical agglomeration to enhance micromeritic properties of high dose API machine, Zetasizer, RMG, FBD,  Description: Exploring Spherical agglomeration as a particle design technique in which HSH, UV, HPLC, DSC, FTIR the compact crystals are transformed into spherical agglomerate to enhance the Language Known: micromeritic properties of high dose API which is facing problem in flowability and direct  English, Hindi, Marathi compression. The resultant spherical agglomerates will offer characteristic size, shape and aspect ratio which could improve its compressibility, packability and flow property.

VRUTI JIGNESHKUMAR PATEL Address: 20,New Houses, Street No.1, At and Post Sojitra, Anand, Gujarat-387240 Contact no.: +918758596554 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/vruti-patel-b13124193

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 9.23 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from A. R. College of Pharmacy and G.H. Patel Institute  Qualified GATE 2018 (Life of Pharmacy, Gujarat Technological University, Gujarat with 8.27 CGPA Sciences)

Dissertation: Skills:  Title: Formulation Development and Characterization of Natural Anti-oxidant based  Handling of equipments for Electrospun Sheet for Oral Cancer formulation development and  Description: Oral cancer is one of the major malignancies in India as well as worldwide. characterization To avoid severe side effects of current therapies; herbal based formulations are preferred  Efficient knowledge of software for prophylaxis and treatment of early stages of cancer. Resveratrol is a natural anti- like Endnote, Chembiodraw, MS office cancer and anti-oxidant; but to solve the issues of solubility and high first pass metabolism associated with this drug it is necessary to deliver it at the site of cancer in the form of Language Known: buccal sheet. Electrospinning is a novel technique which can be explored to form a highly  English, Hindi, Gujarati porous, thin buccal sheet. The sheet can be tailor made as per patient requirement and

helps in reducing drug dose and provides faster onset of action.

59 YOGESHWARI GOKUL BORADE Address: Flat no. 03, Vastusamrudhi society, Shahu nagar, Motwane road, Nashikroad, Nashik, Maharashtra-422101 Contact no.: +917721918090 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/yogeshwari-borade-a1226818a

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  NIPER JEE 2018 Education and Research (NIPER), Ahmedabad with 8.90 CGPA till 2nd semester  GPAT 2018 - AIR 06  2019-20: PG Diploma in Patent law from NALSAR university of Law, Hyderabad  Qualified GATE 2018  2014-18: Bachelor of Pharmacy from NDMVP College of Pharmacy, Savitribai Phule Pune University, Maharashtra with 64.0% Skills:  Well conversant with Zetasizer, Dissertation: UV, HPLC, DSC, FTIR, HPH,  Title: Evaluating the role of stabilizers in solubility enhancement and P-gp efflux Dissolution apparatus, Tablet modulation of poorly soluble P-gp substrate drug compression machine,  Description: Exploring P-glycoprotein (P-gp), is a major efflux transporter responsible for Mastersizer, Rheometer restricting the cellular uptake and distribution of many drugs as well as toxic substances. Lopinavir (BCS class IV) is a P-gp substrate drug which is also having poor solubility Language Known: responsible for its low bioavailability. So, in order to improve its oral absorption, I am  English, Hindi, Marathi currently working on nanocrystals as a formulation approach for lopinavir using different stabilizers that are also known to have P-gp inhibiting potential and evaluation of effect of stabilizers on permeability of lopinavir on everted gut sac model and Caco-2 cell line.

DEBLEENA PAUL Address: 11/12 Mahiskapur Road Durgapur-713205, West Bengal Contact no.: +919830962426 E-mail ID: [email protected] LinkedIn Profile: http://www.linkedin.com/in/debleena-paul-25b306120

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 8.02 CGPA till 2nd semester. GPAT 2018  2014-18: NSHM College of Pharmaceutical Technology, Kolkata, West Bengal with 8.39 CGPA. Skills: Dissertation:  Proficient in handling instruments  Title: Evaluating the Potential of Guar Gum as base material for formulating anti- essential for formulation microbial spray based powder for Diabetic Foot Ulcer preparation and its  Description: Diabetic foot ulcer is associated as the later complications of diabetes. characterization Currently used strategies for the same are hydrogel sheet and amorphous dressings ,  Software skills in Endnote, Honey-impregnated dressings ,Silver-impregnated dressings. ChemDraw, MS Office In this project the potential of Guar gum as base material is investigated for formulating anti-microbial spray based powder for Diabetic Foot Ulcer. Guar gum will be modified Language Known: chemically to introduce cationic group and this modified gaur gum will be characterized.  English, Hindi, Bengali Antimicrobial drug will be incorporated in this powder and it is expected that the powder

will promote synergistic effect.

60 KAJAL SHAILENDRA SHUKLA Address: 51-Marutidham Society, Near Janakpuri, Karodiya Road, Gorwa,Vadodara-391310, Gujarat, India Contact no.: +917069647992 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/kajal-shukla-52051b186

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 Education and Research (NIPER), Ahmadabad with CGPA 8.73 till 2nd semester with AIR 31 & Qualified GPAT  2014-18: Bachelor of Pharmacy from Gujarat Technical University, Gujarat, India with 2018

8.01 CGPA Skills: Dissertation:  Handling experience with  Title: Colon Targeted Delivery System of Chebulinic acid: Formulation Development and instrument like Tablet punching In-vitro Characterization machine, Hot stage, UV- visible  Description: In this project, we are trying to prepare a formulation which might be used spectrophotometer, DSC, to treat colon cancer. To achieve the desired bioavailability and therapeutic activity, it is Dissolution apparatus, etc. required to give the higher amount of drug to colon due to loss of drug in upper GIT which  Software skills in Endnote, also contributes various GI side effects. So, in order to reduce the dose, dosing frequency ChemDraw, MS Office and minimize the side effects we are preparing the microspheres and then enclosing them in to a suitable dosage form like tablet to increase the patient compliance. Here selected Language Known: drug for this formulation is Chebulinic acid which is herbal drug. This prepared dosage  English, Hindi, Gujarati forms will be characterized for different physiochemical parameters.

POOJA BORISA Address: 33, Near Power House, Rose Cottage, P.H.E.D, Mount Abu (Rajasthan) Contact no.: +919460042644 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/pooja-borisa-a57849192

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 9.36 CGPA till 2nd semester Qualified GPAT 2018  2014-18: Bachelor of Pharmacy from B.N. Institute of Pharmaceutical Sciences, Udaipur,  Secured AIR-139 in Students’ Rajasthan University of Health Sciences, Rajasthan with 76.8 % Talent Promotion Examination organized by CWTI Dissertation:  Title: Preparation and Evaluation of Betamethasone Dipropionate Liquid Crystal as Skills: Topical Drug Delivery System for the Treatment of Atopic Dermatitis.  Adept in handling formulation  Description: The topical route of drug delivery possesses the problem of drug permeation equipments and characterization through skin therefore the area of liquid crystals has been explored to overcome this techniques limitation. Liquid Crystals are mesophases which exhibit the properties of liquids as well  Software skills in Endnote, as crystals. They are used for formulating topical drug delivery systems as they mimic the ChemDraw, MS Office structure of stratum corneum and hence enhance the permeation of drug across the skin. Thus, in my research project, liquid crystalline gel of betamethasone dipropionate is Language Known: proposed to be formulated for the treatment of Atopic Dermatitis. This formulation would  English, Hindi, Gujarati also provide hydration effect to the skin and therefore minimize irritation and itching.

61 SANDEEP KAUR Address: V.P.O. Dehriwal, Tehsil Dasuya, Dist. Hoshiarpur, Punjab Contact no.: +918054758655 E-mail ID: [email protected]

Education: Achievements:  2018-20: M. S. (Pharm.) in [Pharmaceutics] from National Institute of Pharmaceutical  Qualified NIPER JEE 2018 & Education and Research (NIPER), Ahmedabad with 8.5 CGPA till 2nd semester GPAT 2018  2014-18: Bachelor of Pharmacy from Rayat Bahra Institute of Pharmacy (Hoshiarpur),  Won Second prize in Singing Punjab Technical University, Punjab with 77.5 %. competition in Annual function in college Dissertation:  Title: Design and development of essential oil loaded microsponges for the treatment of Skills: acne  Efficient in handling M.S. Excel,  Description: Essential oils have enormous applications among which major one is in MS Power point, MS Word etc. aromatherapy. Apart from that these oils also have various healing properties but still their  Handling of instruments use is limited as appropriate carrier system is not available to deliver these on to desired essential for formulation target site. Conventional systems such as direct application and dilution with a vehicle preparation and its suffers from several disadvantages like toxicity and decrease in concentration on dilution characterization as well as rapid volatilization of active medicament. A polymeric carrier known as Microsponge can be the best for delivery of these oils especially for dermatological Language Known: applications.  English, Hindi, Punjabi

SHRUTI VIKAS CHAVAN Address: Plot No. 46, Falgun Colony, Ranapratap Chowk, New Cidco, Nashik-422009 Contact no.: +918796283218 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/shruti-chavan-4b0a67186

Education: Achievements:  2018-20: M. S. (Pharm.) in [Pharmaceutics from National Institute of Pharmaceutical  NIPER JEE 2018 Education and Research (NIPER), Ahmedabad with 7.14 CGPA till 2nd semester  GPAT 2018 - AIR 6  2019-20: PG Diploma in Patent law from NALSAR university of law, Hyderabad  Qualified GATE (life Sciences)  2014-18: Bachelor of Pharmacy from NDMVP’s College of Pharmacy, SPPU, 2018

Maharashtra with 61.08 % Skills: Dissertation:  Technical skills- Electrospraying,  Title: Enhancement of powder properties using electrospraying approach for respiratory Powder Rheometer, DSC, FT-IR, delivery Zeta sizer, UV, Rotary Tablet  Description: Dry powder inhalers have gained tremendous attention in recent times. Punching Machine, HPH Conventionally DPIs are generated using spray drying, jet milling, and spray freeze drying. We are exploring electrospraying technique which can be used to generate low density Language Known: porous powder which can be customized to have desired physicochemical, micromeritic  English, Hindi, Marathi properties which is suitable for delivery to different regions of respiratory tract.

62 SNEHAL VINAY SHENOY Address: B-606 Dheeraj Kiran CHS, Chincholi bunder road, Near infant Jesus School Malad west Mumbai 400064 Contact no.: +919619953526 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/snehal-shenoy-590b50186

Education: Achievements:  2018-20: M. S. (Pharm) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER JEE & GPAT Education and Research (NIPER), Ahmedabad with 9.5 CGPA till 2nd semester 2018.  2014-18: Bachelor of Pharmacy from Bombay college of pharmacy, Mumbai university,  Recipient of the BIRAC- Maharashtra with 7.68 CGPA SRISTI Appreciation Awards Dissertation: 2017.  Worked as Assistant Editor in  Title: Evaluating the effect of mucoadhesive polymers on nasal retention of formulations Pharma Times, 2015-2017. and nose to brain delivery  Description: Formulations when delivered via the intranasal route usually undergo rapid Skills: mucociliary clearance limiting their absorption via the intranasal route to the brain.  Hands on experience of Formulation of mucoadhesive microemulsion of the selected model drug using different formulation equipment like UV, polymers of varied origin would prove to be a useful approach to increase nasal retention. DSC, FTIR, tablet compression, A comparison between the different selected polymers would assist in the evaluation of coater. comparative mucoadhesive strength of the polymers in their role in enhancing nose to  Software like Mendeley, brain delivery of drugs. This would aid in grading the polymers based on their Chembiodraw & MS Office. mucoadhesive ability and finally in defining the best one. The comparative effect of these Language Known: mucoadhesive polymers on the morphology of nasal mucosa will also be evaluated.  English, Hindi, Marathi, French.

SWATI MAHARU BAGUL Address: Plot no. 26A, Shankar nagar, Behind Dandpaneshwar temple, Nandurbar-425412, Maharashtra Contact no.: +918390476970 E-mail ID: [email protected] LinkedIn Profile: https://in.linkedin.com/in/swati-bagul-004663188

Education: Achievements:  2018-20: M. S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  NIPER JEE 2018 Education and Research (NIPER), Ahmedabad with 7.83 CGPA till 2nd semester  GPAT 2018  2014-18: Bachelor of Pharmacy from NDMVP college of pharmacy, Nashik, Savitribai Skills: Phule Pune University, Maharashtra with 64.12%  Acquainted with UV, HPLC,

DSC, FTIR, Zetasizer, Tablet Dissertation: compression machine, HPH  Title: Development and Characterization of Triamcinolone acetonide loaded Gelatin Texture Analyzer, Dissolution based Ocular nanoformulation apparatus (USP Type I, II & IV),  Description: Exploring gelatin as a biodegradable nanocarrier by using Triamcinolone Optical microscope acetonide as a model drug and its application in topical ocular drug delivery. The developed nanoformulation will have improved bioavailability, better patient compliance Language Known: as the dosing frequency will be reduced by showing controlled drug delivery and it will be  English, Hindi, Marathi non-irritant to the eye.

63 CHITRA RAJANI Address: F-7, Jawahar Nagar, Kota, Rajasthan -324005 Contact no.: +917733011579 E-mail ID: [email protected] LinkedIn Profile: https://www.linkedin.com/in/chitra-rajani-1391bb126

Education: Achievements:  2018-20: M.S. (Pharm.) in Pharmaceutics from National Institute of Pharmaceutical  Qualified NIPER - JEE 2018 Education and Research (NIPER), Ahmedabad with 9.3 CGPA till 2nd semester. and GPAT 2018  2014-18: Bachelor of Pharmacy from Arya College of Pharmacy, Rajasthan University of  Published two book chapters Health and Sciences, Rajasthan with 79% aggregate. in Elsevier in the year 2019.  Got 3rd prize in poster Dissertation: presentation in 12th  Title: Assessment of toxicological aspects of intranasal surfactant rich colloidal International Indo-African nanocarriers on nasal mucosa upon frequent exposure. conference’2018.  Description: Intranasal drug delivery is of great value especially when brain targeting is desired. In this context, various surfactant rich colloidal nanocarrier systems have been Skills: widely explored. Surfactant, co surfactant and oils are majorly used excipients inside these  Technical skills: Efficient systems, which may irritate nasal mucosa and impart a significant level of toxicity. The handling of Malvern Zetasizer, designed project work seeks to investigate the likely toxicity imparted by persistent and FTIR, UV-Spectroscopy, DSC, frequent use of such surfactant rich system on nasal mucosa. Hot Stage Microscopy, As a part of experimental work, nasal formulation comprising of different levels of Dissolution Apparatus (I/II). surfactant will be exposed to ex-vivo conditions and extent of injury will be measured. The  Software skills: Microsoft Office, developed formulation will be characterized for physicochemical parameters, in-vitro drug Endnote, Mendeley, Triplot, diffusion and stability studies. Selected formulation will be subsequently administered to ChemDraw. animals for prolonged duration (approximately 2 months) to check the extent of nasal injury. It is expected that this study will help in evaluating the long-term potential toxicity, Language Known: if any, of delivering surfactant rich colloidal system, via intranasal route.  English, Hindi, Punjabi

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9619144172 Pharmaceutics Devendra Choudhary devendrachoudhary34 @gmail.com

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7718816485 Medicinal Chemistry Tanay Dalvi [email protected] m

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CONTACT US: NIPER Ahmedabad, Opposite Air force Station, Palaj, Gandhinagar-382355, Gujarat, India. Phone: +91 7966745555, +91 7966745501 Fax: +91 7966745560 E-mail: [email protected] Website: www.niperahm.ac.in

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