PATHOLOGY IN FOCUS
Vol 4 Issue 4 November 2010 Message from the Chair Inside this issue: I am pleased to Almeida is a leader in Bioinformat- is well deserved recognition of the Faculty Profile: Dr. Li 2 announce the ics and Health Informatics who has outstanding faculty and students recruitment of two made major contributions to devel- we have in the Department of Pa- 3 Where Are They Now? new faculty mem- oping the computational and thology. Endowed Professorship 3 bers to the UAB mathematical tools needed for Department of identifying biomarkers and molecu- Research funding in the Depart- Farewell to Dr. Huang 4 Pathology. Dr. Yi- lar targets for drug discovery. I ment of Pathology has shown sig- 5 Accolades Ping Li (Forsyth Institute, Harvard welcome both of these accom- nificant growth over the last year, Medical Director Evaluation 5 School of Dentistry; see faculty plished individuals to UAB and the in part due to our successful ef- Pathology Book Review 6 profile in this issue) joined our Department of Pathology. forts to obtain ARRA grant funding. department September 1st as a Our NIH grant portfolio now ex- 7 From the Residents Professor in the Division of Mo- The Molecular and Cellular Pathol- ceeds $17 million and total depart- From the Graduate Students 8-9 lecular and Cellular Pathology. Dr. ogy graduate program was re- mental grant support is approxi- Spotlight on Administration 10 Li is an internationally-recognized cently ranked in the top 15% of mately $27 million. These figures scientific investigator and has programs in its field by the Na- are at or near record highs for the 10-11 Pathology Grant Awards been appointed the inaugural Jay tional Research Council. This rank- Department of Pathology and I A Call for Images 11 M. McDonald Professor in Bone ing was determined through a data commend our faculty, staff and Pathobiology. Dr. Jonas Almeida based assessment of research students for their hard work. (The University of Texas MD Ander- doctorate programs in the United son Cancer Center) will join the States. In addition, our program Department of Pathology in Janu- ranked third out of 78 programs Best wishes, ary, 2011 as Professor and Director for average number of publications Kevin A. Roth, M.D., Ph.D. of the Division of Informatics. Dr. per year per faculty member. This
Pathology In Focus Editorial Committee Faculty Profile: Jill Adamski, M.D. Editor-in-Chief: C. Bruce Alexander, M.D. Jill Adam- UAB Hospital, UAB Highlands Hospi- the Tinsley Harrison Research ski, M.D., tal and the Birmingham Veterans Society. R. Pat Bucy, M.D., Ph.D. Ph.D., is the Affairs Medical Center. Rakesh Patel, Ph.D. newest While completing her M.D., she was Walter C. Bell, M.D. faculty Jill completed her M.D., Ph.D. in the awarded the William Boyd Medal, Marisa B. Marques, M.D. member in elite Medical Scientist Training UAB’s highest award for academic Majd Zayzafoon, M.D., Ph.D. the Division Program at UAB. Her Ph.D. work, achievement in Pathology. This Angie Schmeckebier of Labora- involving the regulation of major award is sponsored by the Ala- Margaret Dotzler tory Medicine. In the summer, she histocompatibility antigen (MHC) bama Association of Pathologists. joined the Division as an Assistant class II gene expression, was com- Professor (tenure earning). She is pleted in the laboratory of Profes- She completed her residency in Dept. of Pathology Website: a member of the Transfusion Medi- sor Etty (Tika) Benveniste, Chair of Clinical Pathology and a fellowship www.path.uab.edu cine section, and she is actively Cell Biology. Jill was also active in in Transfusion Medicine at the involved in all aspects of the UAB student research activities, Hospital of the University of Penn- Newsletter E-Mail: Transfusion Medicine Services at and she was elected President of sylvania, one of America’s leading [email protected] Cont’d on page 2
Pathology In Focus Page 2
Faculty Profile: Jill Adamski, M.D. cont’d. training programs. She is boarded sylvania. She was also recognized ideally suited to building a produc- in Clinical Pathology and Transfu- for teaching of medical students tive academic career. sion Medicine. During her resi- and residents at the University of dency, she was active in residency Pennsylvania-School of Medicine. Jill is a native of Wyoming, and she training oversight at University of received her B.S. degree from the Pennsylvania, having been a mem- Jill has quickly gained the respect University of Wyoming. Although a ber of the Graduate Medical Educa- of her clinical colleagues, our resi- Westerner by birth, she is a con- tion Committee, Treasurer of the dents, technologists, and UAB phy- verted Southerner, and we are House Staff Executive Committee, sicians. Once acclimatized to her glad to have her south of the Ma- and an Evaluator for the ACGME new role, she will focus on clinical son-Dixon Line. She and her hus- Internal Review Committee at the scholarship and medical education. band, Greg Winters, live in Home- Hospital of the University of Penn- Her training and experience are wood.
Faculty Profile: Yi-Ping Li, Ph.D. The Division Staff Associate in the Department CNBP which regulates osteocalcin of Molecular of Immunology at the same institu- expression and is important in body and Cellular tion. For the last 20 years, Dr Li part [head] formation in multiple Pathology has been a major contributor to animal models. was most the Harvard system. He advanced fortunate to through the ranks, moving between Dr. Li has continued to bolster the recently re- the Departments of Cytokine Biol- academic quality of the scholarly cruit, Yi-Ping ogy at the Forsyth and the Depart- activities of his trainees. The ca- Li, Ph.D., Jay ment of Developmental Biology at reers trainees follow after leaving a M. McDonald, M.D. Endowed Profes- the Harvard School of Dental Medi- researcher’s laboratory is an impor- sor of Bone Biology and Senior Vice cine to, in 2007, being named a tant measure of the success of a Director for the Center for Meta- tenured Senior Member. mentor. Dr. Li’s trainees have pur- bolic Bone Disease. sued academic careers at SUNY Dr. Li is perhaps best known for Buffalo, Medical College of Georgia, Dr. Li completed his undergraduate work he did with his mentor, Dr. P. Boston University, UCSF, University education at Zhejiang University, Stashenko on the characterization of Florida and Harvard as well as P.R.C. in 1979 and graduate training of the osteoclast proton pump returned to China and Japan, joining (Ph.D. in Molecular Genetics) in subunit ATP6i and on defining the faculties there. He has been suc- 1988, at the Shanghai Institute of importance of the protease cessful in building a world-class Biochemistry. During that time he cathepsin K in osteoclast function. extramurally funded, peer-reviewed embraced the challenges of aca- He has continued his work in os- research program. It is evident that demic life with two academic ap- teoclast biology focusing on its he provides high quality teaching to pointments including an Assistant gene regulation and differentiation graduate students, post-doctoral Professorship at the Shanghai signaling pathways and on other fellows, and to his colleagues both Institute of Biochemistry. Between subunits of the osteoclast proton within and outside his home institu- 1989 and 1990, Dr. Li was a Post- pump. In order to carry out this tion. “We are extremely fortunate to Doctoral Fellow in Molecular Biol- work, his lab has created a large have recruited him to UAB where I ogy at the Center for Biomedical series of transgenic mice and am confident he will further enhance Research, Rockefeller University, other species. Additional studies an already highly academically pro- NY. He completed a second post- performed in his laboratory have ductive career.” stated Victor Darley doctoral experience at the Forsyth offered key insights into the mo- -Usmar, Vice Chair of Research. Institute, Harvard University in lecular basis of bone formation 1993. Concomitantly, he was a and the importance of the gene Pathology In Focus Page 3
Where are They Now?
From the Pathology Residency at UAB are attending Dr. Huang’s giopathy, therapeutic plasma ex- Program Blood Bank lectures and going to change, and thrombotic thrombocy- the shooting range during her topenic purpura. Forensics rotation. Yara Park, M.D. Dr. Park is a member of the Ameri- Currently, Dr. Park is an Assistant can Society for Apheresis, where she Dr. Yara Park Professor of Pathology at the Uni- is active on many committees. She received her versity of North Carolina at Chapel is also a member of the American M.D. degree Hill, where she is Medical Director Society for Clinical Pathology, the from the UAB of Therapeutic Apheresis, Director College of American Pathologists, School of Medicine in 2004. While of the Hematopoietic Progenitor and the American Association of in medical school, she completed a Cell Laboratory, and Associate Blood Banks. Dr. Park lives in Chapel Post-Sophomore Fellowship in Director of Transfusion Medicine at Hill, North Carolina, with her hus- Pathology and also was inducted the McLendon Clinical Laborato- band, Harry, and their two sons, two- into Alpha Omega Alpha Honor Soci- ries. year-old James and baby Andrew. ety. Dr. Park finished her resi- dency training at UAB in June of In 2008, Dr. Park was awarded 2007. In 2007-08, she completed “Best Abstract in Rheumatology” a Transfusion Medicine Fellowship by the American Society for at the University of North Carolina, Apheresis. In addition to aphere- Chapel Hill. Dr. Park’s favorite sis, her interests include HIV- memories from her residency days associated thrombotic microan-
The Jay M. McDonald, M.D. Endowed Professorship in Bone Pathology was Endowed Professorship in Bone Pathobiology Established: recently established by the University of Alabama Board of The Univer- department’s efforts. The endow- September 17, 2010. Li received sity of Ala- ment is named in honor of McDon- his doctorate in molecular genet- Trustees bama Sys- ald, who served as department ics from the Shanghai Institute of tem Board chair from 1990 to 2008. Biochemistry at The Academy of of Trustees Sciences in China. His research established interests center on cellular and the Jay M. The University of Alabama System molecular mechanisms of bone McDonald, Board of Trus- resorption and formation, which M.D. Endowed Professorship in tees appointed Yi has important implications for Bone Pathology in the UAB Depart- -Ping Li, Ph.D. to understanding and treating osteo- ment of Pathology at its meeting the Jay M. porosis and other metabolic bone on September 17, 2010. The en- McDonald En- diseases. dowment will provide for the re- dowed Profes- cruitment and retention of a re- sorship in Bone —These stories were reprinted nowned faculty member with ex- Pathology in the from the Media Relations website pertise in bone pathobiology who UAB Department at UAB. can contribute to and further the of Pathology at its meeting on Pathology In Focus Page 4
Farewell Dr. Shu T. Huang...
Farewell Dr. Shu T. Huang… He directed the Transfusion Service reference for other apheresis prac- By Marisa Marques, M.D. for 25 years and during this time he tices, and physicians throughout the instituted numerous policies to ensure Southeast continually send their pa- When Dr. Shu T. Huang arrived at UAB, that every transfusion we delivered tients to UAB for apheresis treatment. I was in my first year of medical was safe and appropriate for our Dr. Huang’s clinical skills and impec- school, IBM introduced the 64,000-bit hospital patients. He modernized the cable bedside manners are certainly memory chip, and Louise Brown, the Blood Bank practices by introducing recognized by his patients who truly first test-tube baby, was born in Eng- the exclusive use of single-donor feel privileged to be cared for by such land. At that time, Dr. Huang was also platelets, automation, universal leuko- a “giant”. making history. He played a major reduction, etc. role in persuading President Jimmy Dr. Huang has taught generations of Carter to sign a bill giving American On December 19, 1980 (on the day my pathologists and clinicians about the workers the option of retiring at age husband and I had our first date!), the art and science of Transfusion Medi- seventy rather than the traditional first therapeutic apheresis procedure cine. As a tribute to his role in educa- mandatory retirement age of sixty- was performed at UAB under Dr. tion, the Pathology Residents’ Award five. Indeed, the bill was signed on Huang’s supervision. Dr. Huang satis- for Excellence in Laboratory Medicine April 6, 1978, just 5 days after he fied his passion for patient care and Education has been named in his started working at UAB. And now, his curiosity for machines while per- honor. Each rotating resident and more than 3 decades later, Dr. Huang forming apheresis. He truly enjoys fellow on the Transfusion Medicine is retiring from UAB when he turns 70 programming the instrument and service has felt the influence and on November 17. changing operational settings to cus- positive impact of Dr. Huang’s lessons tomize the procedure for each patient. on their future careers. And none of For over 32 years, Dr. Huang has Under his guidance the UAB Apheresis us will ever forget the surprised facial served the UAB community and Service soon became recognized as a expressions he displayed whenever he worked diligently to provide high qual- national leader for therapeutic discovered something amiss on the ity care to thousands of our patients. apheresis. We are now a center of Transfusion Medicine service! We learned more than facts from Dr. Huang, through his example we were also taught compassion, professional- ism, and respect for everyone.
I am so grateful that I had an opportu- nity to learn from and work with Dr. Huang for the past 16 years. His con- tributions to the UAB community and to the lives of his patients and col- leagues are innumerable. We thank him from the bottom of our hearts. We are better people, better physi- cians and a better medical institution because of you, Dr. Huang! Pathology In Focus Page 5
Accolades:
C. Bruce Alexan- speaker at the 8th Annual Confer- search Conference on Throm- der, M.D. was ence of the Australian Biospeci- bospondins and other Matricular elected as the mens Network Association (ABNA) Proteins for the 2013 meeting. President Elect of which will be held in Brisbane, Dr. Murphy-Ullrich was also ap- the American Australia on December 2, 2010. He pointed to the JBC editorial board Society of Clinical will speak on “Factors That Affect beginning July 1, 2010. Pathology (ASCP). the Quality and Usefulness of Tis- sues in Biomedical Research”. Ralph Sander-
son, Ph.D. was Jay M. McDonald, awarded William E. Grizzle, M.D., was awarded (jointly with M.D., Ph.D., a the 2010 Out- Dr. Israel Vlo- longtime mem- standing Lifetime davsky in ber of the edi- Achievement Award Haifa, Israel) toral board of in Clinical Chemis- the Neufeld Clinical Cancer try and Laboratory Memorial Research Award given by Research, a journal of the Ameri- Medicine from the American Asso- the United States—Israel Bina- can Association for Cancer Re- ciation for Clinical Chemistry. search (AACR), has accepted an tional Science Foundation. This invitation to serve as a Senior Joanne award is given annually to the Editor. Murphy- most outstanding and original Ullrich, Binational Science Foundation Dr. Grizzle (past president of the Ph.D. was Supported project in the health International Society of Biological elected as sciences. and Environmental Repositories - the Co- ISBER), will be the plenary keynote Chair of the FASEB Summer Re-
Medical Director Evaluations:
Dr. Marisa B. Marques: vices, for her truly outstanding the Blood Bank/Transfusion Ser- evaluation during FY10. Dr. vices, for being one of the four Marques scored a perfect 100 in medical directors who had the every category of the Hospital most outstanding unit-based/area Medical Director’s evaluation and won an award for one of her proc- process improvement projects ess improvement projects. She during FY10. was the top rated Hospital Medical Director for FY10.
Medical Director Evaluations – FY10 High Achievers Award Winner for Process Im- Congratulations to Marisa provement Marques, MD, Medical Director of Congratulations to Marisa the Blood Bank/Transfusion Ser- Marques, MD, Medical Director of Newsletter Title Page 6
Pathology Book Review: Dr. Margaret covering inflammatory, benign and 2006), and the less well-illustrated Brandwein- malignant diseases of the glands, but more heavily referenced text Gensler published jaws and bones. There is an excel- edited by Gnepp (Diagnostic Surgi- her first single- lent and informative mixture of cal Pathology of the Head and authored text- clinical photographs and imaging Neck, Saunders, 2009), which have book, “Head and studies, as well as macroscopic, been reviewed in previous Bulle- Neck: The Cambridge Illustrated histological and cytological illus- tins. Each of these books deserves Surgical Pathology Series”. This trations of all common and most of a place on the shelves of a labora- book is intended to be a practical the uncommon entities that might tory in order to benefit from the visual guide for surgical patholo- be encountered by head and neck vast experience of the contributing gists and residents. The following surgeons and hence find their way authors. Personal preference will review, written by Dr Tim Helliwell, to the laboratory. determine whether, in everyday has been published in The Bulletin life, one opts for the more pictoral of The Royal College of Patholo- Minor criticisms of what is a re- or more text-based assistance on gists; 2010: 152: 208. markably practical book are varia- offer. tions in colour balance between figures (which do not interfere Dr. Tim Helliwell Head and Neck: The Cambridge with the diagnostic appreciation of Consultant Histopathologist Illustrated Surgical Pathology the subject matter) and the ten- Div. of Pathology, Univ. of Liverpool Series dency, in some places, for the text Margaret Brandwein-Gensler; to be dislocated from the accom- Cambridge University Press, panying figures, particularly where 2010 £95 ($159), 630 pp several figures illustrate a specific ISBM 978 0 521 87999 6 entity. The bibliography for each chapter is restricted to key refer- This book provides a practical ences, which may be difficult to guide to the diagnostic histopa- identify as they are not cited in the thology of the head and neck. As text. befits a publication in this series, the aim is to provide a balance The authoritative approach to between adequately informative diagnosis will be of value to both text and an abundance of figures trainees and more experienced that will assist the surgical pa- pathologists, although some read- thologist in arriving at the correct ers may wish to consult more ‘diagnostic section’ of the book, expansive texts to discover more refining their differential diagnosis detailed information on the condi- and avoiding the more obvious tions described. The book com- pitfalls in arriving at a precise pares favourably with other re- diagnosis for a particular speci- cently published texts on head and men. The book undoubtedly suc- neck pathology and fits in well ceeds in this aim and is a tribute between the more succinct vol- to the experience of the author. umes by Cardesa et al (Pathology of the Head and Neck, Springer- The book is organized in a tradi- Verlag, 2006) and Thompson (Head tional manner, which chapters and Neck Pathology, Elsevier, Pathology In Focus Page 7
From the Chief Residents: From the Chief Residents became available (April 2009). Region in Douglasville, GA. Best of Additionally, to determine the luck Jose! Recruiting season for next year’s benefit, if any, of this antibody resident class is underway. Inter- cocktail compared to using p63 Committees views began in late October and alone. Amy Treece attended the ASCP will run through December. meeting October 27-31 in San Thanks to all the residents who Thuy Nguyen with faculty mentor Francisco as the ASCP resident volunteered to take the applicants Dr. Wei representative. Thuy Nguyen to breakfast and lunch. Please “Characterization of breast cancer attended the Residents’ Forum at help us over the next few months bone metastasis” the CAP meeting September 26-29 in making the applicants feel wel- in Chicago, IL. come during their visit to UAB. Rong Li with faculty mentor Dr. DeVilliers Congratulations to… Darrell Sanders and Goal: Investigate the mechanisms …the following former residents Marian Kraemer of the Hedgehog pathway proteins who passed their boards: Jeremy Chief Residents, 2010-2011 in admantinomatous cranio- Henderson passed hematopathol- pharyngiomas (ACPs). The long ogy boards, Diane Peterson term goal is to apply a biological passed forensics boards, and Adams Grant therapeutic approach by targeting Shaoying Li passed AP/CP boards. Residents remain very active in the Hedgehog pathway. research at UAB, thanks to the Resident Socials funding provided by the Adams Ginny Dailey with faculty mentor The residents continue to meet Grant. Listed below are resident Dr. Brandwein-Gensler every other month for a resident recipients from this year. “Mathematical modeling to classify social. The first social was a BBQ tumor pattern of invasion: A feasi- at John Ross’ house in July and Qian Dai with faculty mentor Dr. bility study” the second social was at Ha- Ren baneros Mexican Restaurant in “Diagnostic utility of NPMc+ in Mock Laboratory Inspection September acute myeloid leukemia” During October, residents partici- pated in a mock inspection of the Amberly Nunez with faculty men- UAB laboratories. Residents were tor Dr. D. Jhala paired with a laboratory technolo- “FISH analysis of EUS-FNAB speci- gist to inspect the labs and then mens to aid in the diagnosis of presented their findings at the seep-seated Lymphoma” summation conference on Novem- ber 1st. This mock inspection was Shuting Bai with faculty mentor held prior to the actual unan- Dr. N. Jhala nounced CAP inspection, which will “Characterization of the function occur sometime between Novem- of regulatory T-cells and mast ber and February. Cookie cake from our BBQ resident social. cells in lymphocytic colitis and collagenous colitis” Farewell The residents wished Jose Lima Residents after Mock Lab John Ross with faculty mentor Dr. farewell at a surprise party on Self-Inspection Summation Hameed October 27th. Jose is leaving UAB Goal: To evaluate the indications to become medical director of the and the diagnostic utility of the American Red Cross Blood Ser- CK5/14/p63/CK7/18 antibody vices, Southeast Division-Southern cocktail as used at UAB since it Pathology In Focus Page 8
From the Graduate Students:
Awards/Accolades: Festival. also received a Young Investigator Travel Award. Angelina Londono Joshi was se- Ashlee N. Higdon received travel lected to the Associate Member awards from the Center for Free In October, Angela represented Council for the AACR. She also Radical Biology and Department of UAB School of Dentistry in the 2010 received a Predoctoral Traineeship Pathology. Both awards are to American Dental Association/ Award from DOD Breast Cancer present at the Society for Free Dentistry Student Clinician Re- Research Program. Radical Biology and Medicine search Program, at the ADA Annual (SFRBM) in Orlando, FL in Novem- Session in Orlando, FL. Her poster Angela Gullard was awarded a ber of this year. Her abstract is was entitled "Dental Alterations Young Investigator Travel Award entitled “Bioenergetic Dysfunction Associated with Camurati- for the 10th International Confer- in Endothelial Cells Precedes Cell Engelmann Disease." ence on the Chemistry and Biology Death due to Hemin: Implications of Mineralized Tissues, to be held for Hemolytic Anemias “. Junghyun Kim— Bolisetty S, Nov. 7-12, 2010, in Scotts- Traylor AM, Kim J, Joseph R, Ricart dale, Arizona. Her abstract enti- Joseph Daft attended the Microbes K, Landar A, Agarwal A.: Heme tled "Dental Alterations Associated and Mucosal Immunity (MMI) con- oxygenase-1 inhibits renal tubular with Camurati-Engelmann Disease" ference and the Gastrointestinal macroautophagy in acute kidney was selected for an oral presenta- Response to Injury (GIRI) confer- injury. J Am Soc Nephrol. 2010 tion at this meeting. ence. Topics discussed at the Oct;21(10):1702-12. Epub 2010 Aug conferences included: bacterial- 12. Junghyun Kim received 3rd Place, epithelial interaction, regulators The best poster presentation and effectors of gut inflammation, Jason Waid Ashley—Jason W Ash- award, 21th annual vascular Biol- and microbial and host mediators ley, Erin M McCoy, Daniel A ogy and Hypertension Symposium, of repair and disease. On Septem- Clements, Zhenqi Shi, Taosheng 9/14/2010. ber 29, he presented a poster Chen, Xu Feng. Development of entitled, “Intestinal barrier func- Cell-Based High-Throughput As- Leah Cook has been accepted into tion and susceptibility to diabetes says for the Identification of Inhibi- the Cancer Prevention and Control in the NOD mouse.” This confer- tors of Receptor Activator of Nu- Training Program in August. A T32 ence strengthened his general clear Factor-Kappa B Signaling. fellowship that will supply Leah’s knowledge of gut physiology and Assay and Drug Development Tech- stipend, fund, and travel money. provided him with many ideas for nologies. In Press. new approaches to his current Erin McCoy received a Predoctoral research. Jason presented this paper at the Traineeship Award from DOD "Osteoporosis in Rheumatic Dis- Breast Cancer Research Program. Publications/Presentations: eases" working group at the She also was awarded a Path ASBMR 2010 Annual Meeting, held Travel Grant to present "Potential Angela Gullard was selected for an October 15-19, 2010, in Toronto, Role of CD68 in breast cancer oral presentation at the Ontario, Canada. bone metastasis" at ASBMR 2010 International Conference on (American Society for Bone and the Chemistry and Biology of Min- Tara Edmonds—Publication: Tara G. Mineral Research) in Toronto Oct eralized Tissues (ICCBMT), to be Edmonds, Haitao Ding, Xing Yuan, 15-19th. held in November in Carefree, Qing Wei, Kendra S. Smith, Joan A. Arizona. Her abstract was entitled Conway, Lindsay Wiecsorek, Bruce Tara Edmonds was selected to "Dental Alterations Associated with Brown, Victoria Polonis, John T. attend the Fifth Annual NIH Na- Camurati-Engelmann Disease" For West, David C. Montefiori, John C. tional Graduate Student Research this same meeting, she Kappes and Christina Och- Pathology In Focus Page 9
From the Graduate Students cont’d… senbauer. "Replication competent Colin Reily— Reily C, Chaco B, General News: molecular clones of HIV-1 express- Srivastava A, Johnson MS, Ulasova Pathology Graduate Student Re- ing Renilla luciferase facilitate the E, Agarwal A, Zinn K, Murphy MP, search Day: analysis of antibody inhibition in Kalyanaraman B, Darley-Usmar V. PBMC". Virology 2010. In press. “Prevention of diabetic nephropa- Poster Presentation Awards thy in Ins2+/-AkitaJ mice by the 1st Erin McCoy Tara also has been invited to give mitochondria-targeted therapy 2nd Michael Alberti Graduate Program Director: an oral presentation entitled Mito Q.” Biochem J 2010 Sept 8. 3rd Joseph Daft
“Comparative analysis of transmit- Rakesh Patel, Ph.D. ted/founder virus infectivity in Scott Tanner—“The Role of Postna- Oral Presentation Award macrophages derived from blood tal Acquisition of the Intestinal 1st Jason Ashley Graduate Program Support: and vaginal tissue” at the CHAVI Microbiome in the Early Develop-
6th Annual Retreat. ment of Immune Function” Journal Guest Speaker: Previous UAB Nicole Newton of Pediatric Gastroenterology and Graduate and Center for Metabolic
Jonathan Hensel—Jonathan A. Nutrition, Volume 51, Issue 3 Bone Disease Student, Valerie 934-2445 Hensel, Diptiman Chanda, Sanjay Meyers, PhD, DABT. Dr. Meyers is Kumar, Anandi Sawant, William E. Scott is also presenting a poster employed at National Aeronautics Grizzle, Gene P. Siegal and Selva- entitled "Altered intestinal homing and Space Administration, Johnson rangan Ponnazhagan. molecule expression prevents Space Center, Houston, TX as a LL-37 as a therapeutic target for effective regulatory T cell traffick- Scientist. late stage prostate cancer. Pros- ing in the FVB.mdr1a-/- model of tate. In Press. colitis" at Immunology 2010, Balti- more, MD; May 7-11, 2010. Pathology In Focus Page 10
Spotlight on Administration: Janice Bowlen
Ms. Janice Hospital and the referring physicians grant receives funding!” Being a Bowlen is an outside UAB, a significant source of support person is also very rewarding OAI in the the patient base at the Hospital. for Janice. “I believe that we should Department grow to the fullest in who we truly are. of Pathology, She had the opportunity to work for I am very capable of taking the lead Division of the Division of Molecular and Cellular when needed, but I am most comfort- Anatomic Pathology for one year, where she able in being a team player and sup- Pathology. learned some of the unique facets of porting the individuals who make She provides the laboratory world. “I was first Anatomic Pathology an outstanding support for six faculty members with exposed to grants back then, when place”. a wide range of duties, from ordering they were ‘mounds of paperwork’. I supplies to helping prepare grants. had told myself I would never do Janice has three children, two grown grants again.” sons and a daughter still in college, Janice began her career at UAB in who are her ‘pride and joy’. She in- 1986 in the Hospital Business Office. After joining Anatomic Pathology, she herited an older home in the city and Next, she joined the Department of was introduced to the new electronic delights in making it her own. She Physician Relations where she was the grant world, and has come to truly lives with her dog and a menagerie of ‘database person’ for the department enjoy being a part of the process. ‘It kitties. along with providing support for the is very rewarding when a faculty R.N.s who were liaisons between UAB member you’ve worked with on a
Pathology Grant Awards
The following grants were recently HIROMI KUBAGAWA MOON NAHM awarded to pathology faculty: NIH/NIAID (ARRA) NIH/NIAID Bacterial Respiratory Pathogens If anyone has any news items, Studies and Structure of an Fc Re- Reference Laboratory Support accolades, etc. to be put in the LEONA COUNCIL ceptor for IgM $349,231 08/01/10-07/31/11 $1,062,781 06/30/10-12/31/11 quarterly newsletter, please UAB Minority Health & Health Dis- send it to the Path In Focus e- parities Research Center Chronic HCV Liver Disease and HIROMI KUBAGAWA KEVIN ROTH mail address at: NIH/NIAID (ARRA Admin Suppl) NIH/NINDS (ARRA) [email protected]. Hepatocellular Carcinoma in African Americans Studies of Paired Immunoglobulin- Alabama Neuroscience Blueprint Like Receptors Core Center Thank you. $60,000 10/01/2010-09/30/11 $201,173 08/09/10-05/31/11 $1,044,000 09/01/10-08/31/11
WILLIAM GRIZZLE DOD ROBINNA LORENZ RALPH SANDERSON Biomarkers in the Detection of Pros- NIH US-Israeli Binational Science Foun- tate Cancer in African Americans Medical Scientist Training Program dation $183,125 09/01/10-08/31/11 $41,209 07/01/10-06/30/15 Novel Heparanase Inhibitors for Myeloma Treatment: Basic Aspects WILLIAM GRIZZLE JOSEPH MESSINA and Clinical Significance NIH VA $25,000 10/01/10-09/30/11 UAB/UMN SPORE in Pancreatic Can- Trauma and Hemorrhage-Induced cer (Core B—Tissue Core) Skeletal Muscle Insulin Resistance CASEY WEAVER $183,622 07/01/10-06/30/11 $261,129 08/01/10-07/31/11 NIH/NIDDKD Innate and Adaptive Microbial Immu- nity in BID (PPG Project 3) $320,485 08/01/10-7/31/15
Pathology In Focus Page 11
Pathology Grant Awards Cont’d:
DANNY WELCH JIANHUA ZHANG Susan G. Komen Foundation VA Regulation of Metastasis by Mito- VA-IPA Xiaosen Ouyang chondrial DNA $60,815 08/02/10-07/31/11 $250,000 07/01/10-06/30/11
JIANHUA ZHANG VA Novel Mechanism of Neuroprotection Against Neurotoxins $200,000 08/02/10-07/31/11
A Call for Images:
If anyone has any news items, images will be rotated into a ban- accolades, etc. to be put in the ner at the top of the website, and quarterly newsletter, please will change periodically. These send it to the Path In Focus e- images should be of high quality mail address at: and in jpeg format. Please send [email protected]. the images to Angie Schmeckebier at [email protected]. If you have any Thank you. The Department is looking for questions, please feel free to call pathology images for use on the her at 934-4558. UAB Pathology website. These can be images of lab personnel, gradu- ate students, faculty awards pres- entations, or tissue staining. The