Anti-HPN Monoclonal Antibody (DCABH-11924) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-HPN monoclonal antibody (DCABH-11924) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description This gene encodes a type II transmembrane serine protease. The encoded protein has an extracellular region that consists of two domains, a catalytic serine protease domain and a non- catalytic scavenger receptor cysteine-rich domain. This protein may be involved in diverse cellular functions including blood coagulation, maintenance of cell morphology and the growth and progression of certain cancers, particularly prostate cancer. Alternative splicing results in multiple transcript variants

Immunogen A synthetic peptide of human HPN is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications Western Blot (Transfected lysate); ELISA

Size 1 ea

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name HPN hepsin [ Homo sapiens ]

Official Symbol HPN

Synonyms HPN; hepsin; serine protease hepsin; TMPRSS1; transmembrane protease; serine 1; transmembrane protease serine 1; transmembrane protease, serine 1; serine protease hepsin catalytic chain; serine protease hepsin non-catalytic chain;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Protein Refseq NP_002142

UniProt ID P05981

Chromosome Location 19q11-q13.2

Function calcium-activated potassium channel activity; peptidase activity; protein binding; scavenger receptor activity; serine-type endopeptidase activity; serine-type exopeptidase activity; serine- type peptidase activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]