7bc Family Motif Enrichment
AP−2gamma 150 AP−2gamma
AP−2alpha
TEAD TEAD1 Sox6 CEBP
Nanog SCL 100 Sox10 Sox17 Sox3 strand
a − Prop1 a +
PRDM10 AR−halfsite 50
Median Motif Enrichment −log(pValue) ZNF165 MITF En1 Pitx1 Maz MNT Lhx3 PPARE CLOCK NPAS2 Usf2
0
1 3 4 5 6 2a Consensus Sequence Block 7d1 Family Motif Enrichment
Tgif1 1200 BMYB Tgif2 MafF
CEBP
800 Prop1 TEAD Nanog strand TEAD1 a − AR−halfsite a +
400
Median Motif Enrichment −log(pValue) AR−halfsite CRX Nanog Pitx1 RXR Pitx1 PPARa EBF1 PU.1:IRF8 EAR2 VDR SPDEF Hoxa9 Sox3 COUP−TFII 0 PRDM10
1 3 4 5 6 2a Consensus Sequence Block 7d2 Family Motif Enrichment
Tgif1
BMYB Tgif2
MafF
1000 CEBP
AR−halfsite TEAD strand TEAD1 a − Nanog a +
500
Median Motif Enrichment −log(pValue) CRX Nanog Pitx1 AR−halfsite Prop1 SPDEF RXR Pitx1 BMYB PPARa EBF1 PU.1:IRF8 AMYB VDR PRDM10 SCL 0 FOXK2
1 3 4 5 6 2a Consensus Sequence Block 7o Family Motif Enrichment
CEBP
Prop1
TEAD 400 Nanog TEAD1
AP−2gamma AP−2gamma SCL strand
AP−2alpha a − a +
200 Hoxd11 Hoxa9 Hoxa11 Median Motif Enrichment −log(pValue) PPARE AR−halfsite PPARa Hoxd12 CDX4 Cdx2 Sox6 RXR Hoxd13 Hoxa13 Maz Sox3 HOXB13 Hoxd10
0
1 3 4 5 6 2a Consensus Sequence Block 7u1 Family Motif Enrichment
Tgif2 Nanog Eomes Sox3
MafF Tgif1 200 Prop1 Isl1 Ascl1 PU.1−IRF
PU.1:IRF8 PRDM1 ZNF7 HEB IRF8 Atoh1 strand a − a +
100
THRa ZNF416 LRF Median Motif Enrichment −log(pValue) Cdx2 CDX4 SCL Hoxd12 Hoxd13
RUNX2 HOXB13 Hoxa13 Hoxa11 Hoxd11 Hoxd10
0
1 3 4 5 6 2a 2b Consensus Sequence Block 7u2 Family Motif Enrichment
EWS:ERG−fusion ELF5 ELF3
150 EHF
En1 100 Lhx3 SCL strand ZFX Pdx1 Ascl1 a − a + Atoh1
HEB
50 Median Motif Enrichment −log(pValue) Slug Sox6 Ptf1a Maz SCL ZEB1 THRa AR−halfsite KLF14 E2A ZNF165 HEB Sp2 HEB KLF1 Ptf1a Snail1 ZEB2 0
1 3 4 5 6 2a 2b Consensus Sequence Block 7up1 Family Motif Enrichment 1250
Pit1 Nanog
Tgif2 Sox3 1000 Eomes MafF Ascl1 Prop1 ZNF467 BMYB Atoh1 Tgif1 750 AMYB Egr1 HEB strand
LRF a − Isl1 a + 500 ZNF7
THRa Gata2 Gata1 Median Motif Enrichment −log(pValue) Gata4 250 KLF5 Gata6 SCL EKLF ZNF416 KLF1 Sp2 E2F3
0
1 3 4 5 6 2a 2b Consensus Sequence Block 7up2 Family Motif Enrichment 400 Pit1
Nanog 300 Tgif2 Eomes Sox3 ZNF467 Prop1 Ascl1 MafF Atoh1 Tgif1 Egr1 strand
200 a − HEB a + LRF
ZEB1 SCL Median Motif Enrichment −log(pValue) 100 Gata2 Gata1 Hoxd11 THRa KLF5 Hoxa11 Isl1 Gata6 Gata4 KLF1 ZNF7 EKLF Hoxd12 Hoxd10
0
1 3 4 5 6 2a 2b Consensus Sequence Block LTR7B Family Motif Enrichment
GSC CRX Maz Otx2
Sox9 Nkx6.1 En1 1500 LHX9 Lhx2
KLF5
1000 Maz GSC strand AMYB TRPS1 a − KLF3 a + AP−2gamma Klf4 KLF6 AP−2gamma CUX1 Hnf6b Cux2 HNF6 AP−2alpha KLF1 EKLF 500 PSE Nkx3.1 Sp2 Median Motif Enrichment −log(pValue)
Nkx2.2
0
1 3 4 5 6 2a 2b Consensus Sequence Block LTR7C Family Motif Enrichment 600 MITF
Sox10 Sox3 400 CUX1 MYB Sox15 HNF6 AMYB Cux2 Sox4 CUX1 Sox2 BMYB Hnf6b Sox9 strand
a − PR PR a + SPDEF TRPS1 GATA:SCL PR AMYB 200 Gata6 AP−2gamma TEAD4 PR Gata4 Median Motif Enrichment −log(pValue) AP−2gamma PGR PSE
0
1 3 4 5 6 2a 2b Consensus Sequence Block LTR7Y Family Motif Enrichment
ELF3 BMYB ELF5
EWS:ERG−fusion AMYB 150 Maz
ZFX EHF En1 SCL Six2 Lhx3 Sox6 KLF5 Sox9 Hnf6b HNF6 CUX1 GSC 100 AR−halfsite Cux2 KLF1 PSE TRPS1 strand Maz AMYB KLF14 a − Klf4 KLF3 a + KLF6
50 Median Motif Enrichment −log(pValue)
0
1 3 4 5 6 2a 2b Consensus Sequence Block