MINISTRY OF PUBLIC HEALTH OF UKRAINE

Department of human resources policy, education and science

Testing Board

Student ID Last name

Variant ______

Test items for licensing examination

Krok 2 PHARMACY

(російськомовний варіант)

General Instruction

Every one of these numbered questions or unfinished statements in this chapter corresponds to answers or statements endings. Choose the

answer (finished statements) that fits best and fill in the circle with the corresponding Latin letter on the answer sheet.

Authors of items: Akzhyhitova I.H., Andreiev V.H., Bilous S.B., Bohdan N.S., Bratenko M.K., Bushuieva I.V., Cholyi L.F., Chornous B.O., Dasiuk Ye.V., Drachuk V.M., Dyba L.D., Hadiak I.V., Haina Zh.M., Hala L.O., Harna N.V., Hasiyk H.D., Herush O.V., Hladkova L.M., Hladyshev V.V., Hlushachenko O.O., Hnidets B.I., Holopykho L.I., Holovkin V.O., Horbata N.Yu., Horoshko O.M., Hromovyk B.P., Hrozav A.M., Hrymaliuk O.I., Hrytsyk A.R., Ivanov E.I., Khokhlenkova N.V., Korovenkova O.M., Koval V.M., Kovalenko S.I., Kovalsky M.Y., Kraidashenko O.V., Kryvoviaz O.V., Lenchyk L.V., Liapunova O.O., Makar R.D., Maksymchuk N.M., Marchyshyn S.M., Mazulin O.V., Melnyk H.I., Muzyka N.Ya., Nemiatykh O.D, Ohar S.V., Okkert I.L., Palamar A.O., Panfilova H.L., Perederyi Ye.O., Pochtar L.Yu., Polova Zh.M., Popova N.V., Rovinsky O.O., Rybak O.T., Rykhlitska K.V., Sakhatska I.M., Shliusar O.I., Sincha N.I., Skryliova N.M., Soboleva B.O., Sofronova I.V., Sokolova L.V., Stadnyichuk R.F., Sych I.A., Syniak, Tereshuk S.I., Tkach Ye.P., Tsveiuk N.P., Tykhonov O.I., Vashchenko K.F., Vereitynova V.P., Vynnyk I.O., Yavorska L.P., Yehorov I.A.,

Yeriomina Z.H., Zaruma L.Ye., Zub L.O. and Committees of professional expertise.

Item reviewers: Burian H.O., Darmograi R.Ye., Hala L.O., Holopykho L.I., Hrytsenko B.I., Khokhlenkova N.V., Korobko D.B., Koval A.Ya., Kovalska N.P., Lenchyk L.V., Lesyk R.B., Levytska O.R., Marchyshyn S.M., Moriak Z.B., Nazarkina B.M., Nemiatykh O.D., Otrishko I.A., Pukhalska I.O., Samohalska O.Ye., Unhurian L.M., Vashchenko K.F., Voitenko L.P., Zhadko S.V.

The book includes test items for use at licensing integrated examination “Krok 2 Pharmacy” and further use in teaching.

The book has been developed for students of pharmaceutical faculties and academic staff of higher medical educational establishments.

Approved by Ministry of Public Health of Ukraine as examination and teaching publication based on expert conclusions (Orders of MPH of Ukraine of 14.08.1998 №251, of 27.12.1999 №303, of 16.10.2002 №374, of 16.04.2003 № 239, of 29.05.2003 №233).

© Copyright Testing Board.

Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 1

1. A pharmacist has prepared powders including extract of A. In a month belladonna in the amount of 0,015 B. In a week per dose. For ten doses he had to C. In 3 days take the following amount of dry D. In 10 days extract: E. In 5 days A. 0,3 g 6. Specify which of the alkaloids gi- B. 0,15 g ven below will react positively to C. 1,5 g xanthines (murexide test): D. 0,03 g E. 0,015 g A. Caffeine B. Atropine sulfate 2. A pharmacy prepared a solution C. Papaverine hydrochloride of macromolecular substance with li- D. Quinine sulfate mited swelling capacity. What soluti- E. Ephedrine hydrochloride on was labelled "warm up before use"? 7. Point out the type of labour division structure of management A. Gelatin personnel: B. Trypsin C. Pepsin A. Horizontal D. Methyl cellulose B. Institutional E. Pancreatin C. Technical D. Administrative 3. A dispensing chemist can E. Upper recommendadrugmadefrom seeds of Aesculus hippocastanum to 8. Losartan is contraindicated for be taken as a veintonic and anti- treatment of arterial hypertension thrombotic agent to treat venous in case of: congestion and veins dilatation of A. Pregnancy lower extremities. This drug is: B. Hyperglycemia A. Aescusan C. Urine acid diathesis B. Phytolysin D. Hyperlipidemia C. Flamin E. Hypokalemia D. Marelin 9. Which of the drugs listed below E. Ajmaline is used for thrombolytic therapy of 4. Specify the normal spoilage ratio myocardial infarction? for toxic drugs, which should be A. Streptokinase taken into account by an inventory B. Heparinum committee during stock-taking. C. Рhenylinum A. 0,95% D. Ticlopidine B. 3,0% E. Acetylsalicylic acid C. 7, 6 % 10. An organisation has been D. No norm defined founded to carry out several E. 1,9% interconnected purposes. What type 5. A schedule of sanitation acti- of organisation is it? ons in pharmacies is regulated by the relevant normative documents. Cleaning day at a pharmacy must be scheduled for at least 1 time: Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 2

A. Complex A. Scopolamine B. Private B. Codeine C. Legal C. Morphine D. Budget D. Platyphyllin E. Small E. Papaverine 11. Representatives of pharmaceuti- 15. Coumarins are natural cal companies have met to discuss compounds with their structure urgent issues of their further work. based on an benzo-alpha-pyrone This meeting belongs to the followi- skeleton. What reaction allows to ng type of organizational groups detect this group of compounds? (teams): A. Lactone test A. Informal groups B. Cyanide test B. Staff C. Iron (III) chloride reaction C. Managed groups D. Wilson’s reaction D. Formal groups E. Trim-Hill reagent E. Role groups 16. The following raw herbal materi- 12. Bellasthesin is a spasmolytic drug al was delivered for analysis: capi- used in treatment of gastrointestinal tulum inflorescence is semicircular diseases. What substance contained or conic in shape; no pedicles or only in Atropa Belladonna provides such their remains; floral disk is naked, an effect of the drug? conic, hollow. Semiflorets are whi- te, disk florets are yellow, involucres A. Hyoscyamine are yellow-green. The smell is speci- B. Morphine fic, aromatic. The taste is bitter-spicy. C. Codeine What raw herbal material is it? D. Reserpine E. Caffeine A. Flores Chamomillae B. Flores Arnicae 13. Stinging nettle (Urtica dioi- C. Flores Calendulae ca) leaves are mostly used as a D. Flores Helichrysi arenarii hemostatic in tinctures and liquid E. Flores Millefolii extract to treat lung, intestinal, and uterine hemorrhages. What bioacti- 17. Standard raw herbal material of ve substance provides hemostatic lily-of-the-valley is obtained by dryi- effect? ng it at a temperature of 50-60oC in order to prevent the possibility of A. Vitamin K the following biochemical process: B. Beta-carotene C. Rutin A. Enzymatic hydrolysis of cardiac D. Reserpine glycosides E. Digitoxin B. Oxidation of phenolic compounds C. Volatilization of essential oils 14. Vitali-Morin’s reaction is used D. Oxidation of resins to identify tropane alkaloids in raw E. Oxidation of terpenoids herbal material. Name the alkaloid that can be detected by this specific 18. A patient with heart failure reaction. induced by long-term coronary vessel disorder can be administered a drug produced out of the following raw herbal material: Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 3

A. Hawthorn berries shape, 4-12 mm in length. The colour B. Calendula flowers of fruit varies from yellow to dark C. Ginseng roots orange. The smell is faint. The taste D. Aralia roots is sour-sweet. What plant is it? E. Berberis roots A. Hippophae rhamnoides 19. A patient came to a pharmacy B. Ammi majus and ordered cowberry leaves. Which C. Aronia melanocarpa of the available raw herbal materials D. Vaccinium myrtillus can be offered as a substitute? E. Coriandrum sativum A. Folium Uvae ursi 24. Cumulating drugs - Digitoxin B. Rizoma Calami and Соrdigitum - are used to treat C. Rizoma et radix Sanquisorbae chronic cardiac insufficiency. What officinalis plant is used as a raw material to D. Herba Achilleae millefolii produce them? E. Radix Taraxaci officinalis A. Digitalis purpurea 20. Specify the pricing strategy of B. Strophanthus kombe international market, which foresees C. Adonis vernalis establishing relatively low prices to D. Convallaria majalis work up the developed countries E. Erysimum canescens market. 25. Business trip can be assigned to A. Penetration strategy employees only with their consent, if B. Premium pricing strategy these employees are: C. Differential pricing strategy D. Price skimming strategy A. Womenwithchildrenfrom3to14 E. Price leveling strategy years of age B. Womenwithchildrenfrom1to3 21. Point out the type of group years of age poll that foresees a single survey of C. Womenwithchildrenlessthan1 several experts to discuss a certain year old problem. D. Any employee E. Women with two children A. Focus group B. Omnibus 26. An analytical chemist working C. Delphi at a pharmacy identifies oxacillin D. Panel sodium salt. As a reagent he uses E. Interview hydroxylamine hydrochloride soluti- on in presence of sodium hydroxide 22. Name the stage of drug life solution and copper nitrate soluti- cycle that is characterized by maxi- on. What structural fragment of the mal sales and profit, and reminder drug molecule can be detected by advertising. these reagents? A. Maturity and saturation A. Beta-lactam cycle B. Growth B. Thiazolidine cycle C. Decline C. Isoxazole cycle D. Introduction D. Furan cycle E. Market exit E. Thiadiazole cycle 23. The following fruit was recei- 27. A pharmaceutical enterprise that ved for analysis: succulent drupes has achieved high sales rates and circular or elongated-ellipsoid in customers’ recognition will reach the Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 4 highest profit at the following stage A. Labour disputes commission of the product life cycle: (LDC) B. Trade union committee A. Maturity C. Highest management bodies of B. Market penetration pharmaceutical service at the regi- C. Growth onal level D. Decrease D. MoH of Ukraine E. Development E. Commercial court 28. A factrory workshop produci- 32. A pharmacist has prepared ng suspensions and emulsions is solution of ethacrydine lactate. developing manufacture of new Name the peculiarity of this drugs. What mechanisms can be substance dissolution. used for ultrasound production of drugs? A. Dissolving in hot water B. Dissolving in freshly distilled A. Liquid whistle, magnetostrictive water source C. Dissolving in cold water B. Dismembrator, electrical impulse D. Grinding in a mortar with water plasmolyzer E. Dissolving in potassium iodide C. Disintegrator, liquid whistle solution D. Rotor-pulsation apparatus, di- smembrator 33. A pharmacy received a prescri- E. Centrifugal mixer with rotating ption for an extemporaneous housing compounded drug. Specify the document that is used to set the pri- 29. A pharmaceutic factory ce for such drug: workshop producing ointments can use the following equipment at the A. Retail price list for drugs packing stage: B. Inventory report C. Certificate of quality A. Screw and piston dosing machines D. Cash receipt voucher B. Rezepin automatic machine E. Certificate of analysis C. Rotary machines D. Eccentric machines 34. Medications Passit and E. Disc machines Novopassit are used as tranquilizing, sedative and mild soporific agents. 30. What preparation is the specific These medications are produced antidote in case of intoxication with from the following grass: iron preparations? A. Purple passionflower A. Deferoxamium B. Three-lobe beggarticks B. Protamine sulfate C. Garden sage C. Bemegridum D. Elecampane D. Atropinum E. Lesser periwinkle E. Penicillamine 35. Thymol is the main component 31. A pharmacist has a labour di- of Thymus serpyllum essential oil. spute with the pharmacy admi- What is the time of harvesting for nistration about rescheduling this raw herbal material? his annual vacation leave. The employee can appeal against the decision of the pharmacy admini- stration to the following body: Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 5

A. Peak florescence period A. Ammonium oxalate B. In autumn after above-ground B. Barium chloride part of a plant dies-off C. Potassium carbonate C. During peak of sap movement D. Silver nitrate D. During fruiting E. Sodium sulfate E. Beginning of vegetation 40. A pharmacy received a prescri- 36. An essential oil is a component ption for vaseline-lanoline based eye of such compound drugs as: ointment. What proportion of vaseli- Inhalypt, Corvalol, Pinosol, ne to lanoline should be chosen by Corvaldin, tooth drops. What raw a pharmacist to make the ointment herbal material is a source of this base? essential oil? A. 9:1 A. Folia Menthae piperitae B. 1:1 B. Folia Betulae C. 5:1 C. Folia Urticae D. 8:2 D. Folia Agavae E. 7:3 E. Folia Absinthii 41. A pharmacist has made an 37. When developing the system althaea root tincture. What proporti- of marketing communications, on of raw herbal material to a company should consider the extractant was chosen by the characteristics of each market pharmacist to make this tincture? promotion means applied for a drug. Which of the following characteristi- A. 1:20 cs is typical for advertising? B. 1:10 C. 1:30 A. Depersonalization (non-personal D. 1:100 communication) E. 1:400 B. Non-mass communication C. Two-way communication 42. Collective labour agreement D. All answers are correct is concluded by a trade union E. There is no correct answer committee with an enterprise owner on behalf of the workforce. Any 38. A pharmaceutical factory collective agreement is worked out produces suspensions and emulsi- in written form. Which article of the ons. Specify the equipment that is Labor Code regulates the duration used for dispersion and mixing in li- of the collective agreement? quid medium: A. 17 A. Rotor-pulsation apparatus, colloid B. 36 mixers C. 38 B. Drum mixers D. 40 C. Oscillating mixers E. 41 D. Anchor mixers E. Gate mixers 43. To stimulate sales a pharmaceuti- cal wholesale company grants its 39. What reagent is used to detect customers a discount according to calcium admixture in medicinal the social contract and on condition substances? of their loyalty. Specify the type of discount: Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 6

A. Bonus A. Phenolic hydroxyl B. Dealer B. Aldehyde group C. Seasonal C. Keto group D. Discounts for quantity of D. Ester group purchased goods E. Alcoholic hydroxyl E. - 48. Production of tablets requires 44. One of the quality indicators for stage-to-stage quality control. What finished ampoules is lack of residual devices are used to determine the stress in the glass. Which operati- particle size distribution (fraction) on at the "Preparation of ampoules of granules? to be filled"stage eliminates this imperfection? A. Standard set of sieves B. Various vibrosieves A. Ampoule annealing C. Friabilators B. Capillary opening D. Laboratory identifiers C. Ampoule washing E. Microscope D. Ampoule drying E. Ampoule sterilization 49. According to the State Pharmacopoeia of Ukraine, in order 45. Companies producing injectable to test a substance for the highest dosage forms apply different level of magnesium impurities an methods of ampoule sealing. Sealing analytical chemist must use the against a jet of inert gases (nitrogen, following solution: argon, carbon dioxide) is suitable for the following injection solutions: A. Hydroxyquinoline B. Resorcin A. Easily oxidable C. Pyridine B. Viscous D. Formaldehyde C. Thermostable E. Benzaldehyde D. Hydrolytically unstable E. Photosensitive 50. Preparations of sorrel roots can have both laxative and astringent 46. A pharmacist prepares a solution effect. Such an effect results from the for injections that must be stabili- presence of the following biologi- zed with 0,1M of hydrochloric acid cally active substances: solution. What solution is to be prepared? A. Anthracene derivatives and tanni- ns A. Novocaine B. Flavonoids and essential oils B. Calcium chloride C. Essential and fatty oils C. Potassium chloride D. Coumarins and phenol glycosides D. Hexamethylenetetramine E. Iridoids and vitamins E. Sodium benzoate 51. Theory of management currently 47. Paracetamol substance has been specifies the four most important sent for analysis. Reaction with approaches to the management. the solution of iron (III) chloride Select the approach that IS NOT resulted in blue-purple colouring. applied in the management theory: This indicates the presence of: Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 7

A. Structured ve chlorine. What reagent is used? B. Process approach C. Systemic A. Ammonium oxalate D. Situational B. Magnesium sulfate E. Different schools dedication C. Potassium chloride approach D. Sodium nitrite E. Ammonium molybdate 52. A pharmacist worked on a holi- day and his work hours were within 56. A set of values, traditi- the norm for the current month. The ons, behavioral norms and vi- employee would be entitled to be ews inherent to an organisation paid: characterize its following feature: A. Fixed salary + one daily rate A. Culture B. Fixed salary + double daily rate B. Success C. According to the standard C. Profitability procedure as for a normal working D. Sapitalization level day E. Self-development capability D. There would be no extra pay E. Single piecework rate 57. Products differentiation (advantages) pursued by a pharmaceutical 53. A pharmacy has a license for company with the aim to surpass its selling narcotic drugs. The warrant competitors in satisfying customers’s for the receipt of these drugs from demands is called: the pharmacy warehouse is valid for: A. Product leadership A. No longer than 10 calendar days B. Benchmarking from the date of issue C. Porter’s generic strategies model B. No longer than 3 months from the D. Penetration strategy date of issue E. Concentration strategy C. No longer than 1 calendar days from the date of issue 58. A patient bought mint leaves at D. No longer than 1 year from the a pharmacy. What recommendati- date of issue ons regarding infusion of this raw E. No longer than 5 calendar days herbal material must be given by a from the date of issue pharmacist? 54. Which of the pharmacy A. The infusion is to be prepared in a departments is responsible for tightly closed vessel checking the quantity and quality of B. The infusion is to be prepared on received goods, their storage and di- open fire spensing to other departments? C. The infusion is to be prepared at room temperature A. Inventory department D. The extract is to be immediately B. Compounding and production filtered after infusing department E. The extract is to be artificially C. Department of finished dosage cooled 15 minutes after infusing forms D. Department of over-the-counter 59. A patient has been administered drugs a solution containing boric acid and E. Department of curative cosmetics camphor. What solvent should his doctor prescribe to prevent physical 55. Chloride of lime is identified by incompatibility? calcium cations after boiling with acetic acid in order to eliminate acti- Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 8

A. Ethyl alcohol 70% 64. A pharmacy makes infusion B. Purified water solutions. Specify the solution that C. Sunflower oil restores water-salt metabolism. D. Glycerol E. Ethyl alcohol 40% A. Ringer-Locke’s solution B. Polyglucinum 60. A patient has chronic pancreati- C. Neohaemodesum tis with apparent presentations of D. Hydrolysine pancreatic exocrine hypofunction. E. Dextran Which of the following drugs would be the most advisable in this case? 65. Prior to making a sodium chlori- de isotonic solution a pharmacist A. Раncreatinum baked the powder in a dry heat box. B. Drotaverine What substances are removed by C. Dе-Nоl this operation? D. Оmерrаzоlе E. Acidin pepsinum A. Pyrogenic substances B. Redox substances 61. A manufacturing company initi- C. Sulfates ates changes to the package insert of D. Chlorides a drug aimed at limitation of its use. E. Moisture What type of marketing is used by the company in this case? 66. Yellow gentian contains bitter glycosides. Raw material of this A. Counteractive plant is recommended for producti- B. Conversion on of drugs with the following effect: C. Remarketing D. Synchromarketing A. Stimulates appetite E. Stimulating B. Tonic C. Diuretic 62. An ampoule workshop produces D. Hepatoprotective injection solutions. What filters are E. Venotonic used for sterile filtering of injection solutions? 67. A pharmacy received a prescri- ption for tincture. What raw herbal A. Membrane and depth filters material can be used to make this B. Druck (pressure) filter dosage form? C. Nutsche (vacuum) filter D. Filter designed at the Kharkiv A. Valerian rootstock Chemico-Pharmaceutical Research B. Rhubarb roots Institute C. Oak bark E. Pressure leaf filter D. Arrow-wood bark E. Buckthorn bark 63. Injection solutions of weak acids and strong bases must be stabilized. 68. A retail pharmacy has been What stabilizers are used for such purchasing goods within an solutions? accounting period. What changes to the balance will result from these A. 0,1 М sodium hydroxide solution business transactions? B. 0,1 М hydrochloric acid solution C. Sodium edetate (Disodium EDTA, Trilon B) D. Ascorbic acid E. Butyloxytoluene Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 9

A. Increase in assets and liabilities A. Potassium tetraiodomercurate B. Decrease in assets and liabilities alkaline C. Changes will be caused to the B. Phenolphtalein assets only C. Iron (III) chloride D. Changes will be caused to the D. Acetic acid liabilities only E. Potassium sulfate E. - 73. A pharmacist prepared a drug 69. Which of the following non- according to the following prescri- steroid anti-inflammatory agents has ption: the least harmful effect on mucosa Rp.: Streptocidi of gastrointestinal tract? Dermatoli ana 1,0 Lanolini A. Nimesulide Vaselini ana 5,0 B. Diclofenac M.D.S.: Apply to the affected skin. C. Indomethacin Specify the type of disperse system: D. Piroxicam E. Acetylsalicylic acid A. Suspension ointment B. Solution ointment 70. When doing calculations to C. Hydrophilic ointment determine the limit of the cash D. Combined ointment balance, an accountant must specify E. Extraction ointment the actual amount of cash receipts. What time period should be taken 74. Efficiency of aerosol therapy is into account? to considerable extent determined by the size of disperse particles. A. Three months prior to calculation What factor determines the size of B. Six months prior to calculation aerosol particles during dispersion C. 1 year prior to calculation of an aerosol? D. 10 days prior to calculation E. 7 days prior to calculation A. Exit port diameter, propellent vapour pressure 71. A doctor wrote a prescripti- B. Reduction range, container on for the tincture of digitalis wi- quantity th hydrochloric acid. What is the C. System homogeneity, dispersion reason for their incompatibility? velocity A. Hydrolysis (with no visible D. Percentage of phase, filling temperature change) E. Fractional composition, containers B. Precipitation filling method C. Gassing D. Change in colour 75. A pharmacist makes powders wi- E. Change in odour th papaverine hydrochloride. What hand scales should be used for wei- 72. During the analysis of diethyl ghing out 0,05 g of substance? ether (Aether medicinales) you can determine presence of aldehydes as aspecific admixture. Which of the following reagents can be used for determining presence of aldehyde admixtures? Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 10

A. BP 1,0 (balance beam scale, stered to a patient with diabetes capacity 1,0) mellitus type II being treated with B. BP 5,0 (balance beam scale, glibenclamid? capacity 5,0) A. Co-trimoxazolum C. BP 20,0 (balance beam scale, B. Midecamycin capacity 20,0) C. Gentamycinum D. BP 10,0 (balance beam scale, D. Benzylpenicillinum capacity 10,0) E. Doxycycline E. BP 2,0 (balance beam scale, capacity 2,0) 80. Plantaglucide is used to treat peptic ulcer disease of stomach and 76. Raw herbal material with the duodenum with normal acidity and following features was delivered to hypoacidity. This drug is obtained a laboratory for analysis: fine flat from the following plant: glossy egg-shaped seeds (one end is sharp, other - rounded). Seed A. Plantago major surface is smooth, vary in colour B. Plantago psyllium from pale yellow to brown, has pale C. Plantago media yellow raphe. No smell is detected. D. Plantago stepposa The taste is slimy and oily. Name this E. Plantago lanceolata raw herbal material. 81. Drug A is in the stage of market A. Flax seeds saturation. In order to push up B. Pumpkin seeds intensive sales, management of the C. Plantago psyllium seeds manufacturing company decided to D. Strophanthus seeds use the following type of advertising: E. Peanut seeds A. Aggressive 77. Activated carbon is used in B. Informational production of injection solutions for: C. Personal sales D. Sales promotion A. Purification E. Public relations B. Buffer system creation C. Antioxidant properties increasing 82. Which of the penicillins given D. Chemical resistance of ampoule’s below can be identified by reaction glass increasing with ninhydrin? E. Ampoules residual stress relaxati- A. Ampicillin on B. Benzylpenicillin (penicillin G) 78. Intoxication cases were observed C. Phenoxymethylpenicillin (penici- during harvesting raw herbal materi- llin V) al containing potent and toxic D. Oxacillin substances. What raw herbal materi- E. Carbenicillin al SHOULD NOT be harvested by underage and pregnant? 83. Preparations of common valeri- an are used in medical practice as A. Celandine grass sedative drugs. The main feature B. Walnut leaves that allows to distinguish valerian C. Valerian rootstock from the admixtures is: D. Buckthorn bark E. Blueberries 79. Which of the listed antibacteri- al drugs should NOT be admini- Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 11

A. Specific odor sodium nitrite and beta-naphthol to B. No specific odor the preparation. As a result intense C. Specifictaste red colouring is observed. What D. Specific color of raw materials functional group is identified by this E. Stems remains reaction? 84. An analytical chemist determi- A. Primary aromatic amino group nes the admixture of sulphates in B. Secondary aromatic amino group boric acid. What is the main reagent C. Sulpho group to be added? D. Carboxyl group E. Aldehyde group A. Barium chloride B. Sodium sulphide 89. Pharmaceutical analyst worki- C. Potassium ferrocyanide ng at the laboratory of the State D. Silver nitrate Inspectorate for Quality Control E. Ammonium oxalate of Medicines identifies the drug substance "Glucose anhydrous"with 85. A pharmaceutical company copper-tartrate solution (Fehling’s conducted an age-specific segment reagent). What is the colour of analysis of the regional antihistami- produced precipitate? ne market. It revealed the lack of antihistamines for children. The A. Red company will consider this segment B. Blue as: C. Black D. Purple A. Amarketniche E. White B. An unattractive segment C. Amarketshare 90. Specify the indicator which D. A segment requiring further measures total contribution of vari- research ous solutes to osmotic pressure of a E. A market door solution: 86. Calcium cations present in drugs A. Osmolality canbedetectedwiththefollowing B. Isohydricity solution: C. Isotonicity D. Isoviscosity A. Ammonium oxalate E. Apyrogenicity B. Silver nitrate C. Potassium permanganate 91. When setting up a joint-stock D. Sodium nitrite company the founders discussed the E. Sodium chloride issues of financial liability. What is the liability of the shareholders in a 87. What stage is the last in making joint-stock company? injection solutions? A. Limited to the value of their A. Labeling shares B. Sterilization B. Limited to the double amount of C. Filtering deposits D. Qualitative control C. Limited to the contributions to E. Quantitative control the statutory fund and their property 88. An analyst of the State D. Limited to the amount of deposits Inspectorate for Quality Control E. Unlimited and solidary identifies "Sulfametoxazol"by addi- 92. A pharmacy opens a bank ng solutions of hydrochloric acid, account to store funds and conduct Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 12 ongoing business transactions. What A. Diversification kind of account should be opened? B. Segmentation C. Conglomeration A. Current D. Integration B. Provisional E. Centralization C. Deposit D. Letter of credit 97. To identify a drug an analytical E. Investment chemist of the State Inspectorate for Quality Control performs a lignin 93. Specify the reaction to identi- test. Specify this drug: fy ester-type drugs, which is requi- red by the regulations of the State A. Streptotcid Pharmacopoeia of Ukraine: B. Ascorbic acid C. Cortisone acetate A. Formation of iron hydroxamates D. Methionine B. Formation of azo dye E. Analgin C. Formation of indophenol D. Formation of 3-bromphenol 98. The main active components E. Formation of tayleohin of hawthorn berries are flavonoi- ds. What is their pharmacological 94. Streptocide, sulfacyl sodium, effect? norsulfazole or sulfadimezinum can be identified by the reaction forming A. Hypotensive and sedative the following substance: B. Laxative and sedative C. Tonic and antispasmodic A. Azo dye D. Diuretic and styptic B. Murexide E. Antispasmodic and anti- C. Tayleohin inflammatory D. Fluorescein E. Iodoform 99. An analytical laboratory recei- ved "Adrenalini tartras"substance 95. A pharmacy makes bulk for analysis. According to the purchases of health and hygiene requirements of the Ukrainian products. An agent works under a State Pharmacopoeia, quantitative contract with a manufacturer and analysis of this substance can be operates on his account. The agent carried out by the method of: may be given exclusive right to sell goods in certain regions. Specify this A. Acidimetry in non-aqueous medi- agent: um B. Acidimetry in aqueous medium A. Wholesale agent C. Iodometry B. Consignee D. Nitritometry C. Commission agent E. Bromatometry D. Broker E. Dealer 100. Quality of dried extracts is assessed according to several cri- 96. A pharmaceutical company has teria. Specify the highest acceptable made a decision to expand its activi- amount of moisture in dried ties. The process of the company’s extracts according to the State activity expansion by penetration Pharmacopoeia of Ukraine. into new fields of the branch is called: Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 13

A. 5% A. Bradykinin B. 25% B. Angiotensin I C. 20% C. Renin D. 75% D. Aldosterone E. 95% E. Natriuretic peptide 101. What is the function of 105. Preparations containing cardi- anhydrous lanolin in the suppository osteroids are produced out of the mass used for suppositories made by following raw herbal material: hand rolling? A. Herba Convallariae A. Plasticizer B. Cortex Quercus B. Solvent C. Radix Taraxaci C. Preservative D. Folia Ficusi Caricae D. Solubilizer E. Folia Sennae E. Emollient 106. A pharmacist has prepared a 102. The basic structure of steroid solution of menthol oil. Specify the hormones is hydrocarbon skeleton - dissolution temperature of the acti- cyclopentane perhydrophenanthrene. ve substance: What natural compound is used for A. 40-50oC testosterone propionate producti- o on? B. 60-70 C C. 30-40oC A. Cholesterol D. 70-80oC B. Indole E. 20-30oC C. Naphthalene D. Phenanthrene 107. The risk can arise from some E. Anthracene forms of activity connected wi- th production of goods and servi- 103. A dispensing chemist was ces, their selling, commodity-money addressed by a patient with the and financial operations, commerce, prescription of acetylsalicylic acid as implementation of socioeconomic antiaggregant. What daily dosage in and scientific-and-technical projects. grams should be recommended for This is the definition of the following him to take on a regular basis? concept: A. 0,1—0,3 A. Business risk B. 0,5-1,0 B. Loss of property C. 1,0-2,0 C. Labour loss D. 2,0-3,0 D. Loss of time E. Over 4,0 E. Financial loss 104. A patient with arterial 108. Admixtures can be accidentally hypertension and chronic bronchi- included in raw herbal material in tis suddenly developed dry cough the process of harvesting, drying and and dyspnea; his body temperature primary processing. Mineral admi- remained without changes. It is xtures include: known that the patient takes captopril. This phenomenon can be A. Sand, earth, stones explained by increased synthesis of: B. Metal objects C. Other similar plants D. Droppings of birds and rodents E. Other organs of the same plant Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 14

109. A pharmaceutical enterprise quid dosage form, if it contains calci- produces neogalenic preparations. um gluconate? What preparation is produced by the Soxhlet circulation apparatus? A. Dissolve it in hot solvent or heat it up to full dissolution A. Аdonisidum B. First grind it to powder when it is B. Digoxin dry or with small amount of solvent C. Corglyconum added D. Lantosidum C. Dissolve in water free of redox E. Сеlanidum subsatances D. Add equal amount of sodium 110. The common method for chloride quantitative determination of drugs E. Dissolve in alkaline medium from the group of alkali metal halogenides is: 114. Concentrated solutions CANNOTbeusedinmixture- A. Argentometry making if: B. Permanganatometry C. Chelatometry A. Aromatic water is solvent D. Alkalimetry B. Purified water is solvent E. Nitritometry C. Mixture contains a potent agent D. Mixture contains syrups 111. When a pharmacist was servi- E. Mixture contains tinctures ng a customer who ordered a nonprecription drug he realized that 115. Tyndallization is used at the patient did not apprehend verbal a pharmaceutical factory as information. Name the communi- one of sterilization methods for cative barriers that arise when words thermolabile substances. What is the or symbols may have different essence of this method? meanings for information sender and recipient: A. Triple heating of solution to 40-60 0C with 24-hour-long intervals in A. Semantic barriers between for thermostating B. Neglect of facts B. Autoclaving at 119-121 0C with C. Nonverbal barriers pressure at 1,0-1,1 atm D. Failure to understand the C. Sterilization with flowing steam at importance of information 100 0C E. Stereotype mentation D. Sterilization with dry heat at 180-200 0C for a lengthy period of 112. A pharmacist should make 200 time ml of 3% sodium bicarbonate soluti- E. Sterilization with high-frequency on for injections. What are the speci- and microwave frequency current fics of making this solution? 116. What final document is used for A. Vial should be filled to 2/3 of its preparation of a report on the di- volume; sterilization at 120 0C for 12 screpancies revealed in the course of minutes inventory taking at a pharmacy? B. No sterilization C. Dissolve by heating; sterilization A. Act on inventory results at 120 0C for 12 minutes B. Inventory item description D. Use stabilizing agent C. Checklist E. Use water free of redox substances D. Commercial report E. Invoice 113. What technology should be chosen by a pharmacist to make a li- 117. Select the reductant required for Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 15 determination of arsenic impurity in A. 20,0 drugs (method 2): B. 10,0 C. 1,0 A. Sodium hypophosphite D. 5,0 B. Hydrochloric acid solution E. 4,0 C. Sodium sulfite solution D. Sodium hydroxide solution 122. Which of the liquids given E. Potassium iodide solution below should be measured by volume in making liquid dosage 118. Choose the substance that is a forms? tropane-derived alkaloid: A. 20% solution of sodium bromide A. Cocaine B. Vaseline oil B. Caffeine C. Diethyl ether C. Strychnine D. Eucalyptus oil D. Pilocarpine E. Glycerine E. Platyphyllin 123. A pharmacy received prescripti- 119. A pharmacy produces some ons for compound powders contai- injection solutions that have to be ning colouring agent. Which of apyrogenic. Solution of the followi- powder components given below is ng substance can be depyrogenized a colouring agent? by the method of adsorption with activated carbon: A. Ethacridine lactate (Rivanol) B. Camphor A. Glucose C. Sulfanilamide B. Atropine sulfate D. Bismuth nitrate C. Papaverine hydrochloride E. Silver proteinate (Protargol) D. Scopolamine hydrobromide E. Platyphyllini hydrotartras 124. A teenager with hyporexia has been recommended to dri- 120. A pharmacy received a prescri- nk medicinal herbal tea of the ption for external use powder following composition: Herba Absi- containing a substance difficult to nthii, Herba Millefolii. Specify the pulverize. What liquid can be used characteristic microscopic features by a pharmacist to disperse this of Artemisia absinthium, which indi- substance? cate its presence in the herb mixture: A. Ethyl alcohol A. T-shaped hairs along the leaf edge B. Purified water B. Simple and capitate hairs C. Water for injections C. Branched, simple and ciliated D. Dimethyl sulfoxide hairs E. Isopropyl alcohol D. Retor-shaped hairs E. Branched and capitate hairs 121. Specify the amount of raw herbal material necessary to make 125. A laboratory received some a dosage form according to the raw herbal material for analysis. following prescription: Take 200 ml The plant had flowerheads up to of motherwort herb solution. Di- 4 cm in diameter, marginal flowers spense. Prescribed dosage is 1 table- were agamic, blue, funnel-shaped; spoon 3 times a day. the inner flowers were bisexual, purple, tubular. What plant has these features? Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 16

A. Centaurea cyanus of chronic hepatitis has been di- B. Solidago virgaurea agnosed with pneumonia. Which of C. Polygonum persicaria the following antibacterial drugs can D. Scutellaria baicalensis be applied in this clinical situation? E. Viola tricolor A. Amoxicillin 126. Quantitative content of B. Tetracycline theophylline can be determined by C. Biseptol alkalimetric titration of nitric acid D. Rifampicin that is quantitatively exudated as the E. Vancomycin result of the following theophylline salt production: 131. A 57-year-old patient is di- agnosed with rheumatoid arthri- A. Silver tis. Anamnesis states peptic B. Potassium ulcer disease. What nonsteroidal C. Sodium anti-inflammatory drug can be D. Ammonium recommended for this patient? E. Lithium A. Celecoxib 127. Complexometric titration B. Diclofenac (chelatometry) allows to determine C. Aspirin quantitative content of: D. Indometacin E. Mefenamic acid A. Calcium lactate B. Sodium citrate 132. A patient suffering from C. Potassium iodide moderately severe pneumonia was D. Sodium thiosulfate prescribed ceftriaxonum once a day. E. Potassium chloride Prescription of ceftriaxonum once a day is due to the fact that the drug: 128. A patient suffers from peptic ulcer disease. In the process of A. Is slowly eliminated from the combined pharmacotherapy his body feces became black. Name the drug B. Has bactericidal effect that could be the cause of this. C. Is pluripotential D. Accumulates in the lungs A. Bismuth subcitrate E. Is poorly absorbed from the B. Omeprazole injection site C. Actovegin D. Metronidazole 133. According to the requirements E. Ranitidine of the State Pharmacopoeia of Ukraine (Addendum 1) a pharmacy 129. A patient suffering from analyst has to apply the following bronchial asthma was diagnosed wi- method for quantitative analysis of th essential hypertension. What anti- potassium iodide: hypertensive drug is contraindicated forthispatient? A. Iodatometry B. Complexonometry A. Propranolol C. Acidimetry B. Captopril D. Alkalimetry C. Amlodipine E. Nitritometry D. Hypothiazid (Hydrochlorothiazi- de) 134. A pharmacy received a prescri- E. Verap ami l ption for an alcohol solution of methylene blue with unspecified 130. A man with a long history alcohol concentration. In this case Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 17 a pharmacist must use ethyl alcohol A. 10 years of the following concentration: B. 7 years C. 5 years A. 60% D. 3 years B. 90% E. 2 years C. 70% D. 96% 139. What principle of goods E. 40% and expenses accounting requi- res presenting results of business 135. Ampoule workshop of a transactions within the same reporti- pharmaceutical factory produces ng period when the transaction procaine hydrochloride solution. occurs? This solution is stabilized by addi- ng: A. Accrual B. Matching A. 0,1 mol/l of hydrochloric acid C. Periodicity solution D. Autonomy B. 0,1 mol/l of sodium hydroxide E. Continuity solution C. 0,1 mol/l of sodium hydrogen 140. What method is recommended carbonate solution by the State Pharmacopoeia of D. 20,0 of sodium hydrogen Ukraine for quantitative determi- carbonate nation of potassium chloride E. 1,5 g of amino-propylene glycol substance that is used in treatment of hypokalemia? 136. What stage of drug life cycle is characterized by quick increase A. Argentometry of its sales amount and customers’ B. Bromatometry recognition? C. Iodometry D. Cerimetry A. Growth E. Polarimetry B. Introduction C. Maturity 141. Who is responsible for recepti- D. Decline on of goods and medical products E. Saturation with simultaneous incoming quality control? 137. Prescriptions for controlled drugs dispensed under the rei- A. Authorized representative mbursement program (except for B. Supplier pharmacist narcotic and psychotropic preparati- C. Pharmacist ons in substance) are issued on the D. Head of pharmacy following prescription form: E. Analyst A. №1 in duplicate 142. A pharmaceutical factory B. №1, single copy produces herbal juice out of fresh C. №1 and №3 raw herbal material. What operation D. №3 in duplicate should be performed at the stage of E. №3, single copy juice purification? 138. Log books of stock-taking A. Heating followed by quick cooling records are kept in a pharmacy for: B. Sedimentation C. Adsorption D. Filtration E. Crystallization Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 18

143. Cash transactions at a pharmacy and acyclovir tablets increases the are recorded in the cashbook. Which risk of: of the following cash transactions IS NOT a receipt transaction? A. Nephrotoxicity B. Hepatotoxicity A. Issuing cash to be accounted for C. Cardiotoxicity B. Recognizing cash receipts from D. Neurotoxicity sales at a pharmacy E. Allergic reactions C. Recognizing cash receipts from sales at pharmacy outlets and kiosks 148. Simultaneous use of doxycycli- D. Return of unused disbursement ne hydrochloride and oral contracepti- funds ve causes: E. Recognizing accrued salaries and advance payable A. Reduction of oral contraceptives effectiveness 144. Which of the following diuretics B. Increase of oral contraceptives SHOULD NOT be administered to effectiveness patients with impaired hearing? C. Increase of antibacterial effect of doxycycline A. Furosemide D. Reduction of antibacterial effect B. Spironolactone of doxycycline C. Clopamide E. - D. Indapamide E. Chlorthalidone 149. In case of simultaneous use of metronidazole and oral anti- 145. A patient, who has been coagulants derived from coumarin taking acetylsalicylic acid, has patients must be warned about: developed hemorrhages of mucous membranes. This phenomenon is A. Potentiation of anticoagulants associated with: effect and risk of bleeding B. Reduction of anticoagulants effect A. Inhibition of prothrombin C. Potentiation of metronidazole synthesis effect B. Increased absorption in gastroi- D. Reduction of metronidazole effect ntestinal tract E. Higher neurotoxicity C. Decreased absorption in gastroi- ntestinal tract 150. Apart from goods sales, there D. Disorder of protein binding are other business transactions that E. Changed volume of distribution can be characterized as goods di- sposal. Which of the following busi- 146. Simultaneous use of paracetamol ness transactions reduces stock at and acetylcysteine causes: pharmacies? A. Reduction of paracetamol A. Disposal of products for business hepatotoxicity needs B. Reduction of anti-inflammatory B. Reclassifying other supplies as action of paracetamol goods C. Inhibition of paracetamol C. Posting oversupply absorption D. Revaluation for packing and D. Increase of mucolytic action of laboratory work acetylcysteine E. Posting glassware E. Increase of paracetamol nephrotoxicity 151. Phenobarbital drug has a sedati- ve, soporific and anti-epileptic effect. 147. Simultaneous use of gentamicin What is its international nonpropri- Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 19 etary name? 156. A drug was delivered to a private pharmacy. The chemi- A. Luminal cal name of the drug acti- B. Nitrofurazone ve ingredient is 2-chloro-10-(3’- C. Chloramphenicol dimethylaminopropyl)-phenothiazine D. Diazepam hydrochloride. Specify this drug: E. Salol A. Chlorpromazine hydrochloride 152. A 70-year-old patient wi- B. Promethazine hydrochloride th stenocardia claims that the C. Trifluoperazine hydrochloride pharmacy sold him a drug that reli- D. Clonidine hydrochloride eved an attack of stenocardia but E. Diphenhydramine hydrochloride instead caused an acute bursting headache. What antihypertensive 157. A pharmacy performs both cash drug can be characterized by such and non-cash transactions. Financial asideeffect? intermediary in the latter is a: A. Nitrosorbid A. Bank B. Amlodipine B. Central regional pharmacy C. Nifedipine C. City administration D. Trimetazidine D. City administration department E. Metoprolol for pharmacy management E. Regional control-analytical 153. Commercial and financial acti- laboratory vity of a pharmacy involves using returnable packaging. Which of the 158. The main method of quantitati- following containers are returned to ve determination of corticosteroids a supplier? is: A. Metal cylinders A. Spectrophotometry B. Packaging materials B. Potentiometry C. Paper boxes C. Cerimetry D. Glass-stoppered bottles D. Argentometry E. Glassware E. Acidimetry 154. To make a liquid №2 159. Thyme grass is used for by Demyanovych prescription production of herbal medical hydrochloric acid should be taken products for treatment of respi- in the following concentration: ratory tract infections. Under the State Pharmacopoeis of Ukraine, A. 24,8 – 25,2% the raw herbal material is subject B. 0,83% to chromatographic identification by C. 98% means of thin-layer chromatography. D. 30% What substances are detected on E. 10% the chromatographic plate after its 155. Menthol has anesthetic and treatment with due reagent? antiseptic effect. What plant is the A. Thymol and carvacrol source of menthol? B. Atropine and hyoscyamine A. Folia Menthae piperitae C. Quercetin and rutin B. Folia Uvae ursi D. Apigenin and luteolin C. Folia Eucalypti E. Arbutin and methyl arbutin D. Folia Salviae 160. Specify the base for antibiotic E. Folia Absinthii ointments: Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 20

A. Protamine sulfate A. 6partsofvaseline+4partof B. Phenindione (Phenylin) lanolin C. Dipiridamol B. 8partsofvaseline+2partof D. Pentoxifylline lanolin E. Theophylline C. 5partsofvaseline+5partof lanolin 165. Which drug of the given D. 7partsofvaseline+3partof below is a first aid antidote for lanolin acute poisoning caused by arsenic, E. 5partsofvaseline+1partof mercury, chromium, and bismuth lanolin compounds? 161. A pharmaceutical company A. Dimercaprol (Unithiol) plans to produce hexamethylenetetrami- B. Prednisolone ne tablets. What production method C. Atropine is optimal for such tablets? D. Adrenaline E. Morphine A. Direct compression with adjuvants B. Forming 166. A 59-year-old patient has been C. Direct compression without using furosemide for a long time to adjuvants treat his cardiac insufficiency. What D. Compression preceded by wet drug for hypokalemia prevention granulation should be used in the given case? E. Compression preceded by dry granulation A. Panangin (Potassium aspartate and magnesium aspartate) 162. Granulation is used to increase: B. Thiotriazolinum C. Acetylsalicylic acid A. Flowability D. Trimetazidine B. Breakup E. Enalapril C. Dissolution D. Volume density 167. A 32-year-old woman that had E. Porosity been undergoing antibiotic therapy for her pneumonia has developed 163. A 46-year-old patient is di- intestine disbacteriosis. What drugs agnosed with cardiac infarction. should she be prescribed? What drug should be prescribed for thrombolytic therapy? A. Probiotics B. Immune-response modulating A. Streptokinase agents B. Nitroglycerine C. Choleretics C. Spironolactone (Verospiron) D. Antacids D. Drotaverine hydrochloride E. Antispasmodics E. Trimeperidine (Promedol) 168. A 53-year-old woman suffers 164. A patient suffering from from ischemic heart disease and trombophlebitis of his lower angina pectoris. What drug can be extremities has developed symptoms used to stop angina pectoris attacks? of heparin overdosage. What drug can be used as an antidote? A. Nitroglycerine B. Drotaverine hydrochloride C. Propranolol D. Dipiridamol E. Acetylsalicylic acid Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 21

169. A patient is 20 years old. After A. Special tabletting machine for she was stung by a bee the patient forming tablets developed Quincke’s disease; rash B. Dragee pan in the form of blisters and papulae C. Double sided tabletting press appeared on her torso. First aid in machine this case should start with admini- D. Rotary tabletting machine stering the following drug: E. Film coater A. Prednisolone 174. To perform transactions wi- B. Penicillin th customers it is necessary for a C. Freshfrozenplasma pharmacy to have a cash register. D. Rheopolyglukin (Dextran) What cash operation is registered by E. Haemodes a cash register as a service payment? 170. A patient with osteoarthritis A. Cash remaining in cash register at (gonarthrosis) and peptic gastric the beginning of workday ulcer in anamnesis must be prescri- B. Sales proceeds bed a NSAID (nonsteroidal anti- C. Encashment inflammatory drug). What drug D. Per diem costs would be the most safe for this pati- E. Merchandise return payments ent? 175. When servicing customers it A. Meloxicam is necessary to maintain cash desk B. Acetylsalicylic acid discipline. A cashier should make C. Ibuprofen records in the cash book: D. Indometacin A. Immediately after the cash E. Metamizole sodium transaction occurred 171. A 20-year-old man suffers from B. Monthly chronic hyperacid type B gastritis. C. Quarterly Choose the antisecretory agent. D. Weekly E. At the end of workday A. Omeprazole B. Drotaverine hydrochlorid 176. Appropriate labor hours per C. Clarithromycin week are being set for pharmacy D. Levofloxacin staff. How many hours compose E. Metoclopramide a working week for administrative staff? 172. In the course of clinical instrumental examination a 45-year- A. 40 old patient was diagnosed with B. 30 chronic helicobacter-associated type C. 35 B gastritis. What group of drugs D. 45 should be prescribed first of all? E. 63 A. Anti-Helicobacter pylori agents 177. According to the law pharmaci- B. Prokinetic agents es have the right to paid leave. Total C. Antacids duration of main and additional D. Reparative drugs leaves cannot exceed the following E. Anti-Muscarinic agents number of calendar days: 173. What equipment is necessary to make trituration tablets? Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 22

A. 59 A. Nitrates B. 30 B. Chlorides C. 24 C. Heavy metals D. 45 D. Ammonium salts E. 63 E. Sulfates 178. According to the regulations of 182. To increase hydrophobic the State Pharmacopoeia of Ukrai- suspension stability a stabilizer is ne the following solution is used to added. Name this stabilizer. detect potassium admixture in medi- cinal substances: A. Polysorbate 80 (Tween 80) B. Sodium chloride A. Sodium tetraphenylborate C. Dimethyl sulfoxide B. Potassium Tetraiodomercurate D. Glucose Solution Alkaline E. Vaseline oil C. Hydroxyquinoline D. Silver nitrate 183. A pharmacy performs stock- E. Tartaric acid taking to check its inventory holdi- ngs. What is the minimal interval 179. What method is used for between inventory checks of fixed quantitative determination of anti- assets? tuberculous drug isoniazid accordi- ng to the regulations of the State A. Once a year Pharmacopoeia of Ukraine? B. Once a quarter C. Twice a year A. Bromatometry, direct titration D. Onceamonth B. Bromatometry, back titration E. Once in 3 years C. Iodometry, back titration D. Iodometry, direct titration 184. A pharmacy performs regular E. Acidimetry, direct titration stock-taking. What is the minimal interval between inventory checks 180. Nitrofural should be identi- of monetary funds and documents? fied by chromatography accordi- ng to the regulations of the State A. Once a quarter Pharmacopoeia of Ukraine. What B. Once in 3 years type of chromatography is used for C. Twice a year such identification? D. Onceamonth E. Once a year A. Thin-layer B. Cation-exchange 185. What inventory holdings of a C. Anion-exchange pharmacy are included by a commi- D. Gas-liquid ttee in a separate inventory during E. Paper partition stock-taking? 181. According to the regulations of A. Medicines delivered to a the State Pharmacopoeia of Ukraine pharmacy during stock-taking diphenylamine solution with sulfuric B. Medical products acid present can be used to detect C. Medicinal herbs the following admixtures in purified D. Bandaging material water: E. Alcoholature 186. Specify the norms of normal spoilage for medicinal leeches, whi- ch should be taken into account by a stock-taking committee. Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 23

A. Amount and nature of disi- A. 7, 6 % ntegrating agents B. 0,65% B. Poor flowability C. 0,85% C. High specific gravity of powders D. No norm defined D. Tablet powder contains lamellar E. 1,9% crystals E. Heterogeneity of granulated 187. A new pharmaceutical enterpri- material se is being founded. Which document of those given below is 192. Hexamethylenetetramine considered to be founding? solution sterility is achieved by: A. Charter A. Filtering through bacterial filters B. Order B. Preserving agents C. Standard act C. Gas diffusion sterilization D. Directive D. Tyndallization method of sterili- E. - zation E. Pressure steam sterilization 188. A pharmaceutical firm uses a set of marketing concepts to manage 193. During qualitative chemical its interactions with consumers. Poi- analysis of nicotinic acid substance nt out one of such concepts. the reaction was conducted, whi- ch resulted in blue colouring. What A. Manufacture improvement reagent was used? B. Staff improvement C. Management improvement A. Copper (II) sulfate solution D. Creative marketing B. Sodium hydroxide solution E. Interactive marketing C. Iron (III) chloride solution 189. Whatratioisusedinmaking D. Thiocyanogen bromide reagent hawthorn tincture? E. Nessler’s reagent A. 1:10 194. What physical constant of a B. 1:2 substance can be used to identi- C. 1:5 fy diphenhydramine hydrochloride D. 1:20 according to the regulations of the E. 1:1000 State Pharmacopoeia of Ukraine? 190. Name the way of injectabulettae A. Fusion temperature application. B. Boiling temperature C. Relative density A. For injection solutions of drugs D. Refractive index B. Peroral E. Specificrotation C. For implantations D. Vaginal 195. Nitroxoline substance is being E. Sublingual analysed for quantitative content of reactant by alkalimetry in non-water 191. What factors affect tablet disi- medium. What titrant and indicator ntegration? are used in the given method? Кrok 2 Pharmacy (англомовнi студенти) 2015 рiк 24

A. Sodium methylate solution, to satisfy the demand for a drug. thymol blue Specify the type of marketing tasked B. Perchloric acid solution, crystal with decrease of excessive demand violet for a product by raising prices, and C. Sulfuric acid solution, stopping advertising and promotion. naphtholbenzein D. Sodium hydrochloride solution, A. Demarketing phenolphthalein B. Creative marketing E. Potassium hydrochloride solution, C. Promotional marketing methyl orange D. Synchromarketing E. Remarketing 196. What department of a wholesale firm is tasked with search 199. What stage of drug life cycle for and analysis of potential suppli- is characterized by a period of slow ers’ commercial offers, as well as increase of sales amount, significant concluding supply contracts and expenses for demand making, and supervision of contract fulfillment? absence of profit? A. Supply department A. Introduction B. Marketing department B. Creation and development C. Shipping department C. Market exit D. Stores development D. Maturity and saturation E. Finance department E. - 197. Pharmaceutical market subjects 200. Grass of yellow hornpoppy that purchase drugs and medical (Glaucium flavum) contains alkaloid products for further resale to make glaucine. What pharmacological aprofit, are called: effect does this plant have because of this alkaloid? A. Dealers B. Manufacturers A. Antitussive C. Consumer organisations B. Expectorant D. Government authorities C. Analgetic E. Individual consumers D. Anti-inflammatory E. Antipyretic 198. A pharmaceutical firm is unable

INSTRUCTIONAL BOOK

Testing Board

TEST ITEMS FOR LICENSING EXAMINATION: KROK 2. PHARMACY.

Kyiv. Testing Board. (English language).

Approved to print 23.03/№25. Paper size 60х84 1/8 Offset paper. Typeface. Times New Roman Cyr. Offset print. Conditional print pages 16. Accounting publishing pages 20. Issue. 261 copies

List of abbreviations

A/G Albumin/globulin ratio A-ANON Alcoholics anonymous ACT Abdominal computed tomography ALT Alanin aminotranspherase AP Arterial (blood) pressure AST Aspartat aminotranspherase BP Blood (arterial) pressure BR Breathing rate bpm Beats per minute C.I. Color Index CBC Complete blood count CHF Chronic heart failure CT Computer tomography DIC Disseminated intravascular coagulation DCC Doctoral controlling committee DM-2 Non-Insulin dependent diabetes mellitus DTP Anti diphtheria-tetanus vaccine ECG Electrocardiogram ESR Erythrocyte sedimentation rate FC Function class FEGDS Fibro-esphago-gastro-duodenoscopy Gy Gray GIT Gastrointestinal tract Hb Hemoglobin HbA1c Glycosylated hemoglobin Hct, Ht Hematocrit HDL High-density lipoproteins HRIDDM HeartInsulin rate dependent diabetes mellitus IHD Ischemic heart disease IU International unit MSEC Medical and sanitary expert committee NIDDM Non-Insulin dependent diabetes mellitus pCO2 CO2 partial pressure pO2 O2 partial pressure Pm Per minute Ps Pulse rate R Roentgen RBC Red blood count Rh Rhesus RR Respiratory rate S1 (S1) Heart sound 1 S2 (S2) Heart sound 2 TU Tuberculin unit U Unit USI Ultrasound investigation V/f Vision field WBC White blood count X-ray Roentgenogram