Takeda Pharmaceutical Company Limited (4502) Consolidated Financial Statements for Fiscal 2012
2. The Takeda Group The Takeda Group consists of 161 companies, including the parent company submitting these consolidated financial statements, 144 consolidated subsidiaries and 16 affiliates accounted for by the equity method. The following chart shows the main business areas of the Takeda Group, the position of the companies that make up the Group within their respective areas of business, and relationships with each business segment.
Japan Overseas
【Ethical drugs】 【Ethical drugs】 Takeda Pharmaceutical Company Limited Company Takeda Pharmaceutical
And others
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Takeda Pharmaceutical Company Limited (4502) Consolidated Financial Statements for Fiscal 2012
Consolidated Subsidiaries and Affiliates accounted for by the equity method
(Consolidated Subsidiaries)
Capital Voting Relationship Area Company name Address (millions of Principal business shares yen) owned (%) Business transactions Other New York, NY, USD 1 Takeda America Holdings, Inc. Ethical Drugs 100.0*13 — — U.S.A. thousand Amer Takeda Pharmaceuticals Deerfield, IL, 100.0 *1 USD 1 Ethical Drugs — — icas International, Inc. U.S.A. (100.0) Takeda Pharmaceuticals Deerfield, IL, 100.0 *1 Purchases drugs from USD 1 Ethical Drugs — U.S.A., Inc. U.S.A. (100.0) Takeda Sao Paulo, BRL 11 100.0 *6 Takeda Distribuidora Ltda. Ethical Drugs — — Brazil million (100.0) Multilab Indústria e Comércio São Jerônimo, BRL 528 100.0 *6,13 de Produtos Farmacêuticos Ethical Drugs — — Brazil, million (100.0) Ltda. Sao Paulo, BRL 24 100.0 *11
Americas Takeda Pharma Ltda. Ethical Drugs — — Brazil million (100.0) Naucalpan, MXN 387 100.0 *11 Purchases drugs from Takeda Mexico S.A. de C.V. Ethical Drugs — Mexico Million (100.0) Takeda Oakville, CND 58 100.0 *11 Purchases drugs from Ethical Drugs — Takeda Canada Inc. Canada Million (100.0) Takeda Caracas, Bolivar fuerte 100.0 *10 Ethical Drugs — — Takeda S.R.L. Venezuela 2 thousand (100.0) Buenos Aires, ARS 18 100.0 *11 Ethical Drugs — — Takeda Pharma, S.A. Argentina Million (100.0) Handles drug research Millennium Pharmaceuticals, Cambridge, MA, 100.0 *1,13 and development on USD 0.1 Ethical Drugs — Inc. U.S.A. (100.0) behalf of Takeda and contract out to Takeda Handles drug research San Diego, CA, 100.0 *1 Takeda California, Inc. USD 1 Ethical Drugs on behalf of Takeda and — U.S.A. (100.0) collaborative research Jupiter, FL, 100.0 *1 Envoy Therapeutics, Inc. USD 1 Ethical Drugs Collaborative research — U.S.A. (100.0) Takeda Vaccines (Montana), Bozeman, MT, 100.0 *1 USD 1 Ethical Drugs — — Inc. U.S.A. (100.0) Handles drug Takeda Global Research and Deerfield, IL, 100.0 *4 development and USD 1 Ethical Drugs — Development Center, Inc. U.S.A. (100.0) acquisition of approval on behalf of Takeda Palo Alto, CA, 100.0 *1 Takeda Ventures, Inc. USD 1 Ethical Drugs — — U.S.A. (100.0) Amsterdam, EUR 280 Takeda Europe Holdings B.V. Ethical Drugs 100.0 *13 — — Netherlands million Danish *12,13 Roskilde, Takeda A/S kroner 113 Ethical Drugs 100.0 — — Denmark thousand (10.4) Takeda Pharmaceuticals Zurich, CHF 2 100.0 *6 Ethical Drugs — — International GmbH Switzerland million (100.0) Takeda Pharmaceuticals London, GBP 4 100.0 *2 Ethical Drugs — —
Euro Europe, Limited United Kingdom million (100.0) *10,13 Konstanz, EUR 71 Purchases drugs from Takeda GmbH Ethical Drugs 100.0 — p Germany million Takeda e (100.0) Takeda Pharma Vertrieb Berlin, EUR 1 100.0 *11 Ethical Drugs — — GmbH & Co. KG Germany million (100.0) Russian Nycomed Distribution Center Moscow, 100.0 *11 ruble 11 Ethical Drugs — — Limited Liability Company Russia (100.0) thousand Milano, EUR 2 80.0 *10 Purchases drugs from Takeda Italia S.p.A. Ethical Drugs — Italy million (80.0) Takeda Linz, EUR 15 100.0 *11 Takeda Austria GmbH Ethical Drugs — — Austria million (100.0)
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Takeda Pharmaceutical Company Limited (4502) Consolidated Financial Statements for Fiscal 2012
Capital Relationship Voting shares Area Company name Address (millions of Principal business owned (%) yen) Business transactions Other
Vienna, EUR 600 100.0 *11 Purchases drugs from Takeda Pharma Ges.m.b.H Ethical Drugs — Austria thousand (100.0) Takeda Paris, EUR 920 100.0 *11 Purchases drugs from Takeda France S.A.S. Ethical Drugs — France thousand (100.0) Takeda Danish Roskilde, 100.0 *5,13 Purchases drugs from Takeda Pharma A/S kroner 810 Ethical Drugs — Denmark (100.0) Takeda million Norwegian Asker, 100.0 *10 Takeda Nycomed AS kroner 79 Ethical Drugs — — Norway (100.0) million Ukrainian Kiev, 100.0 *11 Takeda Ukraine LLC hryvnia 52 Ethical Drugs — — Ukraine (100.0) thousand Brussels, EUR 449 100.0 *10 Takeda Belgium SCA/CVA Ethical Drugs — — Belgium thousand (100.0) Brussels, EUR 6 100.0 *10 Purchases drugs from Takeda Christiaens SCA/CVA Ethical Drugs — Belgium million (100.0) Takeda Buckinghamshire, GBP 91 100.0 *6,13 Purchases drugs from Takeda UK Limited Ethical Drugs — United Kingdom million (100.0) Takeda Euro Oy Leiras Takeda Helsinki, EUR 1 100.0 *10 Ethical Drugs — — Pharmaceuticals Ab Finland million (100.0) p
e Pfäffikon, CHF 550 100.0 *11 Takeda Pharma AG Ethical Drugs — — Switzerland thousand (100.0) Takeda Farmaceutica Madrid, EUR 1 100.0 *11 Purchases drugs from Ethical Drugs — Espana S.A. Spain million (100.0) Takeda Hoofddorp, EUR 10 100.0 *11 Purchases drugs from Takeda Nederland B.V. Ethical Drugs — Netherlands million (100.0) Takeda Swedish Solna, 100.0 *10 Takeda Pharma AB kroner 2 Ethical Drugs — — Sweden (100.0) million Warsaw, Polish zlotys 100.0 *10 Takeda Pharma Sp.z.o.o. Ethical Drugs — — Poland 191 million (100.0) Athens, EUR 3 100.0 *11 Purchases drugs from Takeda Hellas S.A. Ethical Drugs — Greece million (100.0) Takeda Handles drug Kilruddery, EUR 92 Takeda Ireland Limited Ethical Drugs 100.0 *13 manufacture on behalf of — Ireland million Takeda Cambridge, GBP3 100.0 *2 Handles drug research on Takeda Cambridge Limited Ethical Drugs — United Kingdom million (100.0) behalf of Takeda Handles drug Takeda Global Research and London, GBP800 100.0 *2 development and Development Centre (Europe), Ethical Drugs — United Kingdom thousand (100.0) acquisition of approval Ltd. on behalf of Takeda Takeda (China) Holdings Co., Shanghai, USD 75 Ethical Drugs 100.0 — — Ltd. China million
Takeda Pharmaceuticals (Asia SGD 152 Purchases drugs from Singapore Ethical Drugs 100.0 *13 — million Takeda Pacific) Pte. Ltd. Guangdong Techpool Bio- Guangzhou, CNY 100 51.3 *11 Ethical Drugs — — Pharma Co., Ltd. China million (51.3) Takeda Pharmaceutical (China) Taizhou, USD 62 100.0 *8 Ethical Drugs — —
Asia Company Limited China million (100.0) Tianjin Takeda Pharmaceuticals Tianjin, USD 44 Purchases drugs from Ethical Drugs 100.0 — Co., Ltd. China million Takeda Takeda Pharmaceuticals Korea Seoul, KRW 1,000 100.0 *9 Purchases drugs from Ethical Drugs — Co., Ltd. Korea million (100.0) Takeda Bangkok, THB 102 Purchases drugs from Takeda (Thailand), Ltd. Ethical Drugs 52.0 — Thailand million Takeda Takeda Pharmaceuticals Taipei, TWD 90 Purchases drugs from Ethical Drugs 100.0 — Taiwan, Ltd. Taiwan million Takeda Jakarta, Rp 1,467 Purchases drugs from P.T. Takeda Indonesia Ethical Drugs 70.0 — Indonesia million Takeda
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Takeda Pharmaceutical Company Limited (4502) Consolidated Financial Statements for Fiscal 2012
Capital Relationship Voting shares Area Company name Address (millions of Principal business owned (%) yen) Business transactions Other
Takeda Pharmaceuticals Manila, PHP 97 Purchases drugs from Ethical Drugs 100.0 — (Philippines), Inc. Philippines million Takeda Asia SGD 2 100.0 *3 Takeda Singapore Pte. Limited Singapore Ethical Drugs — — million (100.0) Takeda Global Research & Handle drug SGD 5 Development Center (Asia) Pte. Singapore Ethical Drugs 100.0 development on behalf of — million Ltd. Takeda South African
Others Johannesburg, 100.0 *7 Takeda (Pty.) Ltd. rand 1 Ethical Drugs — — South Africa (100.0) million Takeda Pharmaceuticals Sydney, AUD 451 100.0 *7 Ethical Drugs — — Australia Pty. Ltd. Australia thousand (100.0) Chiyoda-ku, Tokyo, 87.5 Sells drugs, etc., Nihon Pharmaceutical Co., Ltd. 760 Ethical Drugs — Japan (0.2) to Takeda Handle drug Takeda Bio Development Chiyoda-ku, Tokyo, development and 975 Ethical Drugs 100.0 — Center Limited Japan acquisition of approval on behalf of Takeda Ja Leases land p and an Takeda Healthcare Products Fukuchiyama, Consumer Sells over-the-counter 400 100.0 buildings Co., Ltd. Kyoto, Japan Healthcare drugs to Takeda from Takeda Wako Pure Chemical Chuo-ku, Osaka, 70.3 2,340 Others Sells reagents to Takeda — Industries, Ltd. Japan (0.3) Mizusawa Industrial Chemicals, Chuo-ku, Tokyo, 1,519 Others 54.2 — — Ltd. Japan
(Affiliates accounted for by the equity method)
Capital Voting Relationship Area Company name Address (millions of Principal business shares yen) owned (%) Business transactions Other
Amato Pharmaceutical Fukuchiyama City, Consumer Sells over-the-counter Japan 96 30.0 — Products, Ltd. Kyoto, Japan Healthcare drugs to Takeda
(Note): 1. The “Capital” column represents the amount rounded to the nearest million if the company’s capital is more than one million. If the company’s capital is more than one thousand and less than one million, it is rounded to the nearest thousand. 2. The “Principal business” column represents business segment information. 3. Wako Pure Chemical Industries, Ltd. issues a securities report (yuka shoken hokokusho) to the Financial Services Agency in Japan. 4. Figures in parenthesis in “Voting shares owned" represent the percentage indirectly owned by Takeda Pharmaceutical Company Limited. 5. Company (Companies) with *1, *2, *3, *4, *5, *6, *7, *8, and *9 are directly owned by Takeda America Holdings, Inc., Takeda Europe Holdings B.V., Takeda Cambridge Limited, Takeda Pharmaceuticals U.S.A., Inc., Takeda A/S, Takeda Pharma A/S, Takeda GmbH, Takeda (China) Holdings Co., Ltd., Takeda Pharmaceuticals (Asia Pacific) Pte. Ltd., respectively. 6. Companies with *10 and *11 are indirectly owned by Takeda Pharma A/S and Takeda GmbH, respectively. 7. Company with *12 is directly owned by Takeda Pharmaceutical Company Limited(89.6%) and Takeda Europe Holdings B.V.(10.4%), respectively. 8. Companies with *13 are qualified as specified subsidiaries. 9. In April 2012, Takeda Canada Inc. was merged to Nycomed Canada Inc.(Surviving Company), and in May 2012, Nycomed Canada Inc. was renamed to Takeda Canada Inc.. 10. In April 2012, Nycomed France S.A.S. was renamed to Takeda France S.A.S.. 11. In April 2012, Takeda Pharmaceuticals Asia Private Ltd. was merged to Nycomed Holdings (Asia Pacific) Pte. Ltd., and was renamed to Takeda Pharmaceuticals (Asia Pacific) Pte. Ltd.. 12. In May 2012, Nycomed A/S was renamed to Takeda A/S. 13. In May 2012, Takeda Pharma AG was merged to Nycomed Pharma AG (Surviving Company), and Nycomed Pharma AG was renamed to Takeda Pharma AG. 14. In June 2012, Nycomed Belgium SCA/CVA was renamed to Takeda Belgium SCA/CVA. 15. In June 2012, Nycomed Christiaens SCA/CVA was renamed to Takeda Christiaens SCA/CVA. 16. In June 2012, Nycomed B.V. was renamed to Takeda Nederland B.V.. 17. In June 2012, Takeda America Holdings, Inc. acquired URL Pharma, Inc. and its 19 subsidiaries and they became wholly owned subsidiaries of Takeda America Holdings, Inc. Later, in October 2012, the core business was absorbed into Takeda Pharmaceuticals U.S.A., Inc. and in February 2013, the other business was sold.. 18. In July 2012, Takeda Pharma Ges.m.b.H was merged to Nycomed Pharma GmbH (Surviving Company), and Nycomed Pharma GmbH was renamed to Takeda Pharma Ges.m.b.H.
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Takeda Pharmaceutical Company Limited (4502) Consolidated Financial Statements for Fiscal 2012
19. In July 2012, Multilab Indústria e Comércio de Produtos Farmacêuticos Ltda. was acquired and it became a wholly owned subsidiary of Takeda Pharma A/S. 20. In August 2012, Nycomed S.A. de C.V. was renamed to Takeda Mexico S.A. de C.V.. 21. In September 2012, Takeda Pharmaceuticals Korea Co., Ltd. was merged to Nycomed Korea Co., Ltd. (Surviving Company), and Nycomed Korea Co., Ltd. was renamed to Takeda Pharmaceuticals Korea Co., Ltd.. 22. In September 2012, Takeda Farmaceutica Espana S.A. was merged to Nycomed Pharma S.A. (Surviving Company), and Nycomed Pharma S.A. was renamed to Takeda Farmaceutica Espana S.A.. 23. In September 2012, Takeda Pharma Vertrieb GmbH & Co. KG was established. 24. In October 2012, Nycomed Pharma Sp.z.o.o. was renamed to Takeda Pharma Sp.z.o.o.. 25. In October 2012, Takeda America Holdings, Inc. acquired LigoCyte Pharmaceuticals, Inc.. Later, in March 2013, LigoCyte Pharmaceuticals, Inc. was renamed to Takeda Vaccines (Montana), Inc.. 26. In November 2012, Nycomed Venezuela S.R.L. was renamed to Takeda S.R.L.. 27. In November 2012, Nycomed Danmark ApS was renamed to Takeda Pharma A/S. 28. In November 2012, Nycomed Pharma AS was renamed to Takeda Nycomed A/S. 29. In November 2012, Oy Leiras Finland AB was renamed to Oy Leiras Takeda Pharmaceuticals Ab. 30. In November 2012, Nycomed Pty. Ltd. was renamed to Takeda Pharmaceuticals Australia Pty. Ltd.. 31. In November 2012, Takeda America Holdings, Inc. acquired Envoy Therapeutics, Inc.. 32. In November 2012, Takeda Pharma GmbH was merged to Nycomed GmbH (Surviving Company), and Nycomed GmbH was renamed to Takeda GmbH. 33. In November 2012, Takeda Pharmaceutical Company Limited acquired 50% of the shares of Takeda Pharmaceuticals (Philippines), Inc., and Takeda Pharmaceuticals (Philippines), Inc. became a wholly owned subsidiary of Takeda Pharmaceutical Company Limited. 34. In November 2012, Laboratoires Takeda was merged to Takeda France S.A.S. (Surviving Company). 35. In January 2013, Takeda Italia Farmaceutici S.p.A. was merged to Nycomed S.p.A. (Surviving Company), and Nycomed S.p.A. was renamed to Takeda Italia S.p.A.. 36. In February 2013, Nycomed Austria GmbH was renamed to Takeda Austria GmbH. 37. In February 2013, Nycomed Ukraine LLC was renamed to Takeda Ukraine LLC.
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