Coding for

Audio Seminar/Webinar April 2, 2009

Practical Tools for Seminar Learning

© Copyright 2009 American Health Information Management Association. All rights reserved.

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AHIMA 2009 Audio Seminar Series • http://campus.ahima.org/audio i American Health Information Management Association • 233 N. Michigan Ave., 21st Floor, Chicago, Illinois

Faculty

Robert S. Gold, MD

Dr. Gold is founder and CEO of DCBA, Inc., a consulting firm that provides physician-to-physician clinical documentation improvement programs (CDIP), as well as audit and education services to healthcare organizations. Dr. Gold has over 42 years of experience as a physician, medical director, and consultant. He is also a frequent speaker on clinical data quality, coding, and compliance issues for AHIMA and other organizations.

AHIMA 2009 Audio Seminar Series ii

Table of Contents

Disclaimer ...... i Faculty ...... ii Objectives ...... 1 Agenda ...... 1 Concepts and Definitions Clinically Speaking… Conundrum: Myel/Myelo- ...... 2 Blood Cell Lines ...... 2 Peripheral Blood and Diagram ...... 3 Peripheral Blood and Bone Marrow ...... 3 Get to Know Your Blood Cells ...... 4 Hematology Tests: Reference Value Examples ...... 4 Get to Know Your Blood Cells ...... 5 WBC Differentials and “Shifts” ...... 5 Red Cells Common Codes ...... 6 Subcategory 285.2x, Anemia in Chronic Illnesses ...... 6 Anemia Designations ...... 7 Coding Clinic References ...... 7 Myelodysplastic Conditions Myeloproliferative Disorders ...... 8 Coding Perspective and DRG Assignment ...... 8-9 Blood Cell Lines ...... 9-10 Coding Perspective and DRG Assignment ...... 10-11 White Cells Blood Cell Lines ...... 11 Rationale & Clinical Insight ...... 12 Coding Perspective and DRG Assignment ...... 12 Blood Cell Lines ...... 13 Rationale & Clinical Insight ...... 13 Coding Perspective and DRG Assignment ...... 14 Neutropenias ...... 14 Blood Cell Lines ...... 15 Coding Perspective and DRG Assignment ...... 15 Leukemoid Reaction – 288.62 ...... 16 Other –osis ...... 16 Blood Cell Lines ...... 17 Clinical Insight ...... 17 Platelets Primary Thrombocytopenia ...... 18 Thrombocytes (platelets) ...... 18 Rationale ...... 19

(CONTINUED) AHIMA 2009 Audio Seminar Series

Table of Contents

Clinical Aspects Platelets and Platelet Deficiencies ...... 19 The Primary Thrombocytopenias ...... 20 Chapter 4 Diseases of the Blood and Blood-Forming Organs (280-289) ...... 21 Current Status ...... 22 Lymphatic Cell Lines ...... 22 Clinical Perspective REAL ...... 23 Mature B-Cell Tumors (NHL) ...... 23-24 Mature T-Cell and Natural Killer Cell Tumors (NHL)...... 24-25 Hodgkin’s Lymphoma ...... 25 -Associated Lymphoproliferative Disorders ...... 26 Histiocytic and Dendritic Cell Neoplasms (CNS) ...... 26 Classification by Immunologic Subtype and Aggressiveness ...... 27 Our Newer Subdivisions (2007) ...... 27 Leukemias (204 – 208 series) ...... 28 Maturation in the Bone Marrow ...... 28 Leukemias ...... 29 Other Hematologic Conditions Code series 289.8x ...... 29 Hypercoagulable States ...... 30 Coding – Primary Hypercoagulable State (289.81) ...... 30 Coding – Secondary Hypercoagulable State (289.82) ...... 31 Coding – HIT – Heparin-Induced Thrombocytopenia (289.84) ...... 31 Coding Clinic Reference ...... 32 Bone Marrow Procedures Procedure Issues in Hematology ...... 32 CPT® Assistant Reference ...... 33 Bone Marrow Aspiration (38220) ...... 33 Procedure : Bone Marrow Aspiration ...... 34 Bone Marrow Biopsy (38221) ...... 34 Procedure : Bone Marrow Biopsy ...... 35 Bone Marrow Aspiration (38220) vs. Biopsy (38221) ...... 35 Resource/Reference List ...... 36

Audio Seminar Discussion ...... 36 Become an AHIMA Member Today! ...... 37 Audio Seminar Information Online ...... 37 Upcoming Audio Seminars ...... 38 Thank You/Evaluation Form and CE Certificate (Web Address) ...... 38

Appendix ...... 39 Resource/Reference List ...... 40 CE Certificate Instructions

AHIMA 2009 Audio Seminar Series Coding for Hematology Notes/Comments/Questions

Objectives

Š Identify various hematological disorders and applicable ICD-9-CM diagnostic codes Š Review relevant AHA Coding Clinic references and clinical documentation practices to support accurate hematology coding Š Review bone marrow procedures and related code assignments

1

Agenda

Š Overview of blood cell lines Š Anemia Š Myelodysplastic disease Š Š Leukemoid reaction Š Thrombocytopenia Š Hematologic neoplasms Š Hypercoagulable states 2

AHIMA 2009 Audio Seminar Series 1 Coding for Hematology Notes/Comments/Questions

Clinically Speaking... Conundrum: Myel/Myelo-

Myel/Myelo- Myel/Myelo- “Myel,” as in “myelitis” or “Myel,” as in “myelopathy,” refers to “myelodysplasia” or the spinal cord “myelofibrosis,” refers Š myelitis is inflammation of to the bone marrow the spinal cord Š myelofibrosis is fibrosis of Š myelopathy is disease of the bone marrow the spinal cord Š myelodysplasia exists when the bone marrow does not produce enough mature blood cells

3

Blood Cell Lines

Š 238.71 Essential thrombocythemia Š 238.72 Low grade lesions Š 238.73 High grade myelodysplastic syndrome lesions Š 238.74 Myelodysplastic syndrome with 5q deletion Š 238.75 Myelodysplastic syndrome, unspecified Š 238.76 Myelofibrosis with myeloid metaplasia Š 238.79 Other lymphatic and hematopoietic tissues 4

AHIMA 2009 Audio Seminar Series 2 Coding for Hematology Notes/Comments/Questions

Peripheral Blood and Bone Marrow

5

Peripheral Blood and Bone Marrow

Suffixes: Š -osis – too many of (thrombocytosis – too many platelets, erythrocytosis too many red cells) Š -emia – in the blood (thrombocythemia – too many platelets in the peripheral blood; anemia – not enough blood) Š -ia – excess of ( – too many basophils) Š -penia – too few of ( – too few white cells, thrombocytopenia – too few platelets) Š -plasia – production of (aplasia – no production of) 6

AHIMA 2009 Audio Seminar Series 3 Coding for Hematology Notes/Comments/Questions

Get to Know Your Blood Cells

Granulocytes

Platelets among Segmented erythrocytes Basophil

Lymphocyte Mononuclear white cells 7

Hematology Tests: Reference Value Examples

Cell Type Too Few Range Too Many

Red Cells Anemia Hb 13(12) - 18(16) Erythrocytosis

Platelets Thrombocytopenia 150,000 - 400,000 Thrombocytosis

All White Cells Leukocytopenia 4,300 - 10,800 fGranulocytes Granulocytopenia Granulocytosis Polymorphonuclears (PMNs)

- Neutropenia 50% - 70%

- 1% - 3%

-Basophils Basophilopenia 0.4% - 1% Basophilia fAgranulocytes Agranulocytopenia Mononuclears - Lymphocytopenia 25% - 35%

- 4% - 6% 8

AHIMA 2009 Audio Seminar Series 4 Coding for Hematology Notes/Comments/Questions

Get to Know Your Blood Cells

Mononuclears Polymorphonuclear leukocytes

9

WBC Differentials and “Shifts”

"Normal" Differential

Mets Bands SegmentedNeutrophils/PolymorphonuclearLeukocytes Lymphocytes Monocytes Eos Baso 0% 0-5% 60-75% 20-35% 0-10% 0-5% 0-3%

Left Shift

Mets Bands Segmented Neutrophils/Polymorphonuclear Leukocytes Lymphocytes MonosEos Bas

Right Shift

Segmented MetsBands Neutrophils/Polymorphonuclear Lymphocytes Monocytes Eos Baso Leukocytes

10

AHIMA 2009 Audio Seminar Series 5 Coding for Hematology Notes/Comments/Questions

Common Anemia Codes

Š 285.1 – anemia due to acute blood loss FROM… name it Š 280.0 – anemia due to chronic blood loss FROM… name it Š 285.21 – anemia in chronic kidney disease – effect of chronic kidney disease Š 285.22 – anemia in neoplastic disease – effect of the tumor Š 285.29 – anemia in chronic illness – and name that illness (chronic hepatitis, lupus, osteomyelitis, etc.)

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Subcategory 285.2x, Anemia in Chronic Illnesses

Š These codes can be used as the principal/first listed code if the reason for the encounter is to treat the anemia. Š They may also be used as secondary codes if treatment of the anemia is a component of an encounter, but not the primary reason for the encounter. Š When using a code from subcategory 285.2x, it is also necessary to use the code for the chronic condition causing the anemia.

12

AHIMA 2009 Audio Seminar Series 6 Coding for Hematology Notes/Comments/Questions

Anemia Designations

Š 284.89 – Acquired (secondary) aplastic anemia. Includes that due to antineoplastic chemotherapy. Š 285.0 – Refractory (primary) anemia due to drug, toxin or hereditary. Also includes congenital, drug-induced, hereditary, sex-linked hypochromic and vitamin B6- responsive refractory . Š 238.72 – Idiopathic refractory (primary) anemia or that due to myelodysplastic syndrome.

13

Coding Clinic References

Š Anemia of chronic disease • CC 4th Qtr 2008, volume 25, number 4, pages 195-201 • CC 4th Qtr 2000, pgs 39-40 – Diseases associated with anemia in chronic illness – if you don’t know the chronic disease and it’s not linked to the anemia, 285.29 is not the code! Š Anemia due to chemotherapy • CC 2nd Qtr 2008, pg 6 (284.89 + E933.1) 14

AHIMA 2009 Audio Seminar Series 7 Coding for Hematology Notes/Comments/Questions

Myeloproliferative Disorders

Š Conditions resulting from Š Essential thrombocythemia – variations in the bone bone marrow produces too marrow’s ability to many megakaryocytes – release proliferate (produce by too many platelets – reproduction) cell lines spontaneous coagulation, blood Š Acute disorders may be clots, embolism result of stimulants or Š Myelodysplastic syndromes of poisonings other cell lines – neoplasms with Š Chronic disorders may be excessive production of blasts late effects of above or and release of few mature forms primary bone marrow into peripheral blood disorders • Too few red cells, inadequate oxygenation and organ failures Š May be too many or too few in peripheral blood • Too few white cells, subject to overwhelming 15

Coding Perspective and DRG Assignment

Š Alpha: Syndrome, myelodysplastic; Thrombocytopenia Š Tabular: Chapter 2, Neoplasms (140-239) Š IPPS MDC: • MDC 16, Diseases and Disorders of the Blood and Blood-Forming Organs and Immunological Disorders • MDC 17, Myeloproliferative Diseases and Disorders and Poorly Differentiated Neoplasms Š As PrDx: • For 238.71-238.75 • DRG 811 Red blood cell disorders w MCC • DRG 812 Red blood cell disorders w/o MCC 16

AHIMA 2009 Audio Seminar Series 8 Coding for Hematology Notes/Comments/Questions

Coding Perspective and DRG Assignment (cont’d)

Š As PrDx: • For 238.76-238.79 • DRG 823 Lymphoma & non-acute w other O.R. proc w MCC • DRG 824 Lymphoma & non-acute leukemia w other O.R. proc w CC • DRG 825 Lymphoma & non-acute leukemia w other O.R. proc w/o CC/MCC • DRG 840 Lymphoma & non-acute leukemia w MCC • DRG 841 Lymphoma & non-acute leukemia w CC • DRG 842 Lymphoma & non-acute leukemia w/o CC/MCC • DRG 820 Lymphoma & leukemia w major O.R. procedure w MCC • DRG 821 Lymphoma & leukemia w major O.R. procedure w CC • DRG 822 Lymphoma & leukemia w major O.R. procedure w/o CC/MCC

17

Blood Cell Lines

Š 284.01 Constitutional red blood cell aplasia limitation of production of red cell line only due to in utero infection by Parvovirus or other viral infection

Š 284.09 Other constitutional aplastic anemia reduction in all three cell lines – hereditary disorder (Fanconi’s anemia)

18

AHIMA 2009 Audio Seminar Series 9 Coding for Hematology Notes/Comments/Questions

Blood Cell Lines

Š 284.1 Pancytopenia A “lab finding code” showing that all three cell lines are deficient – justifies studies – need conclusions as to etiology. Aplastic anemia's result in pancytopenia.

Š 284.2 Myelophthisis

Invasion of bone marrow with cells or bacteria or fungi that replace and crowd out the cells that make blood or support the cells that make blood, leading to deficiency in all cell lines.

19

Coding Perspective and DRG Assignment

Š Alpha: Syndrome, Blackfan-Diamond; Anemia, Fanconi’s; Pancytopenia, Myelophthisis Š Tabular: Chapter 4, Diseases of the Blood and Blood-Forming Organs (280-289) Š IPPS MDC: • MDC 16, Diseases and Disorders of the Blood and Blood-Forming Organs and Immunological Disorders • MDC 17, Myeloproliferative Diseases and Disorders and Poorly Differentiated Neoplasms Š As PrDx: • For 284.01-284.09 • DRG 811 Red blood cell disorders w MCC • DRG 812 Red blood cell disorders w/o MCC 20

AHIMA 2009 Audio Seminar Series 10 Coding for Hematology Notes/Comments/Questions

Coding Perspective and DRG Assignment (cont’d)

Š As PrDx: • For 284.1-284.2 • DRG 823 Lymphoma & non-acute leukemia w other O.R. proc w MCC • DRG 824 Lymphoma & non-acute leukemia w other O.R. proc w CC • DRG 825 Lymphoma & non-acute leukemia w other O.R. proc w/o CC/MCC • DRG 840 Lymphoma & non-acute leukemia w MCC • DRG 841 Lymphoma & non-acute leukemia w CC • DRG 842 Lymphoma & non-acute leukemia w/o CC/MCC • DRG 820 Lymphoma & leukemia w major O.R. procedure w MCC • DRG 821 Lymphoma & leukemia w major O.R. procedure w CC • DRG 822 Lymphoma & leukemia w major O.R. procedure w/o CC/MCC 21

Blood Cell Lines

Š 288.0 Neutropenia, unspecified Š 288.00 Neutropenia, unspecified Š 288.01 Congenital neutropenia Š 288.02 Š 288.03 Drug induced neutropenia Š 288.04 Neutropenia due to infection Š 288.09 Other neutropenia

22

AHIMA 2009 Audio Seminar Series 11 Coding for Hematology Notes/Comments/Questions

Rationale & Clinical Insight

Š The understanding of Š Neutropenia is a hematological disorders hematological disorder has grown over the years. characterized by an Š Not feasible to reclassify abnormally low number of all of these conditions; neutrophil (a decision to provide specific type of white blood cells). codes. Š Neutrophils make up 50- Š It will be useful for better 70% of all circulating white comparison to differentiate blood cells. the various disorders and Š Neutrophils serve as the to consistently classify primary defense against them between ICD-9-CM by destroying and ICD-10-CM. bacteria in the blood. 23

Coding Perspective and DRG Assignment

Š Alpha: Neutropenia Š Tabular: Chapter 4, Diseases of the Blood and Blood- Forming Organs (280-289) Š IPPS MDC: • MDC 16, Diseases and Disorders of the Blood and Blood-Forming Organs and Immunological Disorders • MDC 25, Human Immunodeficiency Virus Infections Š As PrDx: • DRG 814 Reticuloendothelial and immunity disorders w MCC • DRG 815 Reticuloendothelial and immunity disorders w CC • DRG 816 Reticuloendothelial & immunity disorders w/o CC/MCC • DRG 977 HIV w or w/o other related condition

24

AHIMA 2009 Audio Seminar Series 12 Coding for Hematology Notes/Comments/Questions

Blood Cell Lines

Š 288.4 Hemophagocytic syndromes

destruction of all three cell lines but not from lack of precursor cells – from destruction of maturing cells in bone marrow or in peripheral blood

Š 288.50 Leukocytopenia, unspecified – all white cell lines deficient Š 288.51 Lymphocytopenia – lymphocyte deficiency only Š 288.59 Other decreased count 25

Rationale & Clinical Insight

Š New code for Š disorders macrophage have an excessive and disorders 288.4 was abnormal activation of created due to the , which are mature forms of the rare nature of these monocytes of the blood disorders. and blood marrow. Š Allow better Š These macrophages statistical capture of destroy blood cells, cause this condition. liver damage and promote problems.

26

AHIMA 2009 Audio Seminar Series 13 Coding for Hematology Notes/Comments/Questions

Coding Perspective and DRG Assignment

Š Alpha: Syndrome, hemophagocytic; Hemophagocytic syndrome Š Tabular: Chapter 4, Diseases of the Blood and Blood- Forming Organs (280-289) Š IPPS MDC: MDC 16, Diseases and Disorders of the Blood and Blood-Forming Organs and Immunological Disorders Š As PrDx: • DRG 814 Reticuloendothelial and immunity disorders w MCC • DRG 815 Reticuloendothelial and immunity disorders w CC • DRG 816 Reticuloendothelial & immunity disorders w/o CC/MCC 27

Neutropenias

Terminology is important Š Neutropenia only neutrophils are deficient (see leukocytopenia later, 288.50) Š Agranulocytosis (granulocytopenia) implies deficiency of neutrophils, eosinophils and basophils but functionally only impacts neutrophils – 288.0x series Š Granulocytosis is excessive granulocytes (see later, 288.6x)

28

AHIMA 2009 Audio Seminar Series 14 Coding for Hematology Notes/Comments/Questions

Blood Cell Lines

Š 288.60 Leukocytosis, unspecified Š 288.61 Lymphocytosis (symptomatic) Š 288.62 Leukemoid reaction Š 288.63 Monocytosis (symptomatic) Š 288.64 Plasmacytosis Š 288.65 Basophilia Š 288.69 Other elevated white blood cell count 29

Coding Perspective and DRG Assignment

Š Alpha: Leukocytosis; Lymphocytosis; Monocytosis; Plasmacytosis; Basophilia Š Tabular: Chapter 4, Diseases of the Blood and Blood- Forming Organs (280-289) Š IPPS MDC: MDC 16, Diseases and Disorders of the Blood and Blood-Forming Organs and Immunological Disorders Š As PrDx: • DRG 814 Reticuloendothelial and immunity disorders with MCC • DRG 815 Reticuloendothelial and immunity disorders with CC • DRG 816 Reticuloendothelial & immunity disorders w/o CC/MCC 30

AHIMA 2009 Audio Seminar Series 15 Coding for Hematology Notes/Comments/Questions

Leukemoid Reaction – 288.62

Š Excessive production or release of white cells in response to infection Š Number over 50,000 (normal 5,000 – 10,000) Š Must rule out leukemia's Š We are used to seeing WBC increases in response to steroids and assigning 288.8 and E932.0 – NOT a leukemoid reaction 31

Other -osis

Š Leukocytosis – abundance of white cells – does not specify which line • Present in bacterial infections • Must rule out myelogenous leukemia Š Monocytosis – abundance of monocytes • Seen in mononucleosis • Must rule out monocytic leukemia Š Plasmacytosis – abundance of plasma cells • Must rule out (multiple myeloma) 32

AHIMA 2009 Audio Seminar Series 16 Coding for Hematology Notes/Comments/Questions

Blood Cell Lines

Š 289.53 Neutropenic splenomegaly Š 289.83 Myelofibrosis

33

Clinical Insight

Š Neutropenic splenomegaly – a group of conditions in which it is believed that the spleen traps neutrophils through some mechanism and causes a decrease in peripheral circulating neutrophils; synonyms: • Splenic neutropenia • Doan-Wiseman syndrome – 1938, Doan and Wiseman described a condition in which neutropenia was helped by splenectomy. Š Myelofibrosis – primary form is unknown scarring of bone marrow, leading to decrease in all cell lines (another aplastic anemia results) 34

AHIMA 2009 Audio Seminar Series 17 Coding for Hematology Notes/Comments/Questions

Primary Thrombocytopenia

Š 287.30 Primary thrombocytopenia, unspecified Š 287.31 Immune thrombocytopenic purpura Š 287.32 Evan’s syndrome Š 287.33 Congenital and hereditary thrombocytopenic purpura Š 287.39 Other primary thrombocytopenia

35

Thrombocytes (platelets)

36

AHIMA 2009 Audio Seminar Series 18 Coding for Hematology Notes/Comments/Questions

Rationale

Š 287.3 has included non-essential modifiers for a variety of thrombocytopenic conditions, excluding thrombotic thrombocytopenic purpura 446.6 and transient thrombocytopenic purpura of the newborn 776.1. All are primary (not caused by another process) but have different primary etiologies. Š This breakdown permits better designation of the type of the primary etiologies.

37

Clinical Aspects Platelets and Platelet Deficiencies

Š Platelets (or thrombocytes) are very small cellular components of blood that help the clotting process by sticking to the lining of blood vessels. Š Platelets are made in the bone marrow and survive in the circulatory system for an average of 9-10 days before being removed from the body by the spleen. Š Platelets are vital to life, because they help prevent massive blood loss resulting from trauma, as well as blood vessel leakage that would otherwise occur in the course of normal, day-to-day activity. Š Normal counts are about 150,000 to 350,000. With counts under 50,000, a patient is prone to have spontaneous bleeding. 38

AHIMA 2009 Audio Seminar Series 19 Coding for Hematology Notes/Comments/Questions

The Primary Thrombocytopenias

Š The immune thrombocytopenic Š Evans’ Syndrome is a purpura idiopathic combination of ITP and thrombocytopenic purpura (ITP). autoimmune hemolytic Š Occurs in children after a viral anemia (AIHA). infection and is often self- limited. Š May be associated with neutropenia in 15% of Š In adults, lasts longer, again patients. often following a viral infection or taking some medications or Š Cause is unknown. during a pregnancy. Š Can have transient Š May involve the body’s immune course or be recurrent system developing a tendency to and even fatal. destroy the body’s own platelets. 39

The Primary Thrombocytopenias

Š Congenital and hereditary thrombocytopenia (its title should be that way, not purpura) is a hereditary condition of decreased production of platelets, not of immune origin as is ITP. Normal platelet count Where ITP responds to certain immunologic drugs, as steroids or immune globulins, congenital thrombocytopenia does not. It’s fortunately a rare variety of primary thrombocytopenia. Thrombocythemia (-osis) 40

AHIMA 2009 Audio Seminar Series 20 Coding for Hematology Notes/Comments/Questions

Chapter 4 DISEASES OF THE BLOOD AND BLOOD-FORMING ORGANS (280-289)

Š 287 Purpura and other hemorrhagic conditions • Excludes: hemorrhagic thrombocythemia (238.7) Š 287.3 Primary thrombocytopenia • Evans' syndrome • Megakaryocytic hypoplasia • Purpura, thrombocytopenic • Congenital • Hereditary • Idiopathic 41

Chapter 4 DISEASES OF THE BLOOD AND BLOOD-FORMING ORGANS (280-289) (cont’d)

Š Thrombocytopenia: • Congenital • Hereditary • Primary Š Tidal platelet dysgenesis Š Excludes: • Thrombotic thrombocytopenic purpura (446.6) • Transient thrombocytopenia of newborn (776.1)

42

AHIMA 2009 Audio Seminar Series 21 Coding for Hematology Notes/Comments/Questions

Lymphoma Current Status

Š Lymphomas have been named by their discoverer or by some oddity of their activity, related to other diseases or manifestations

Š Recently divided into Hodgkins and high- grade, intermediate grade and low grade activity Non-Hodgkin’s lymphoma (NHL)

Š WHO (World Health Organization) has standardized the nomenclature proposed by the Revised European-American Lymphoma classification (REAL) 43

Lymphatic Cell Lines

• B-cell lymphocytes • T-cell lymphocytes • Natural killer cell lymphocytes • And other minor groups

44

AHIMA 2009 Audio Seminar Series 22 Coding for Hematology Notes/Comments/Questions

Clinical Perspective REAL Revised European-American Lymphoma Classification

Š First classified by cell type – the cell which, if normal, most closely looks like the tumor cell • B-cell tumors • T-cell tumors • Natural killer cell tumors • And other minor groups

http://dir.niehs.nih.gov/dirlep/liverpath/hyperplastic/lymph5.htm 45

Mature B-Cell Tumors (NHL)

Š Chronic lymphocytic leukemia/small lymphocytic lymphoma Š B-cell prolymphocytic leukemia Š Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia Š Splenic marginal zone lymphoma Š Plasma cell neoplasms – plasma cell myeloma, plasmacytoma, monoclonal deposit disease, heavy chain diseases Š Extranodal marginal zone B cell lymphoma (mucosa-associated lymphoid tissue, MALT lymphoma) 46

AHIMA 2009 Audio Seminar Series 23 Coding for Hematology Notes/Comments/Questions

Mature B-Cell Tumors (NHL) (cont’d)

Š Nodal marginal zone B cell lymphoma Š Š Š Diffuse large B cell lymphoma Š Mediastinal (thymic) large B cell lymphoma Š Intravascular large B cell lymphoma Š Primary effusion lymphoma Š /leukemia Š Lymphomatoid granulomatosis 47

Mature T-Cell and Natural Killer Cell Tumors (NHL)

Š prolymphocytic leukemia Š T cell large granular lymphocytic leukemia Š Aggressive NK cell leukemia Š Adult T cell leukemia/lymphoma Š Extranodal NK/T cell lymphoma, nasal type Š Enteropathy-type T cell lymphoma Š Hepatosplenic T cell lymphoma Š Blastic NK cell lymphoma 48

AHIMA 2009 Audio Seminar Series 24 Coding for Hematology Notes/Comments/Questions

Mature T-Cell and Natural Killer Cell Tumors (NHL) (cont’d)

Š /Sezary syndrome Š Primary cutaneous CD30-positive T cell lymphoproliferative disorders • Primary cutaneous anaplastic large cell lymphoma • Š Angioimmunoblastic T cell lymphoma Š Peripheral T cell lymphoma, unspecified Š Anaplastic large cell lymphoma 49

Hodgkin’s Lymphoma

Š Nodular lymphocyte-predominant Š Classical Hodgkin lymphoma • • Mixed cellularity • Lymphocyte-rich • Lymphocyte depleted or not depleted

50

AHIMA 2009 Audio Seminar Series 25 Coding for Hematology Notes/Comments/Questions

Immunodeficiency-Associated Lymphoproliferative Disorders

Š Associated with a primary immune disorder Š Associated with the Human Immunodeficiency Virus (HIV) Š Post-transplant Š Associated with Methotrexate therapy

51

Histiocytic and Dendritic Cell Neoplasms (CNS)

Š Histiocytic sarcoma Š Langerhans cell Š Langerhans cell sarcoma Š Interdigitating dendritic cell sarcoma/tumor Š Follicular dendriticcell sarcoma/tumor Š Dendritic cell sarcoma, unspecified

52

AHIMA 2009 Audio Seminar Series 26 Coding for Hematology Notes/Comments/Questions

Classification by Immunologic Subtype and Aggressiveness

Š B cell Š T cell • small lymphocytic • peripheral T-cell • lymphoplasmacytic • anaplastic large • follicular T/null cell • marginal zone, MALT • lymphoblastic • marginal zone, nodal • mantle cell • diffuse large B cell • primary mediastinal large B cell • Burkitt's-like 53

Our Newer Subdivisions (2007)

Š 200.3x Marginal zone Š .x0 Unspecified site Š 200.4x Š .x1 Head, face, neck nodes Š 200.5x Primary CNS Š .x2 Intrathoracic nodes Š 200.6x Anaplastic large Š .x3 Intraabdominal nodes cell Š .x4 Nodes axilla, upper limb Š 200.7x Large cell Š .x5 Inguinal, lower limb lymphoma Š .x6 Pelvic nodes Š 202.70 Peripheral T-cell Š .x7 Spleen Š .x8 Multiple sites 54

AHIMA 2009 Audio Seminar Series 27 Coding for Hematology Notes/Comments/Questions

Leukemias (204 – 208 series)

Š Acute varieties (208.0) Š Chronic varieties (208.1) • Myelogenous – all bone marrow – mostly granulocytes • Granulocytic – neutrophilic, basophilic, eosinophilic precursors – blasts • Histiocytic • Lymphocytic (lymphoid – synonyms) • Monocytic (monocytoid – synonyms) • Megakaryocytic (platelet precursors) • Plasmacytic (plasma cell) 55

Maturation in the Bone Marrow

56

AHIMA 2009 Audio Seminar Series 28 Coding for Hematology Notes/Comments/Questions

Leukemias

Š Chemotherapeutic regimens depend on stage Š Initial acute – remission induction – to induce remission Š In remission – consolidation chemo Š In relapse (recurrence) – may need reinduction to induce remission again Š Beware of chronic lymphoma with TRANSFORMATION! May become acute leukemia! Ask the physician! 57

Code Series 289.8x

This code series has been expanded to include:

Š 289.81 Primary hypercoagulable state Š 289.82 Secondary hypercoagulable state Š 289.84 Heparin-induced thrombocytopenia (HIT) Š 289.89 Other specified diseases of blood and blood-forming organs

58

AHIMA 2009 Audio Seminar Series 29 Coding for Hematology Notes/Comments/Questions

Hypercoagulable States

Š This has become more and more identified in the last two years in patients with DVT and embolic phenomena Š It has led to the use of Coumadin for anticoagulation in addition to the usual DVT patient or the Atrial fibrillation or the patient with MI or occlusive stroke – and the problems that arise from long- term Coumadin use

59

Coding – Primary Hypercoagulable State (289.81) Conditions due to inborn errors and lack of certain chemicals that influence the prevention of clot formation under normal conditions Š Antithrombin deficiency Š Protein C deficiency Š Protein S deficiency Š Activated Protein C Resistance Š Dysfibrinogenemias Š Inherited abnormalities of fibrinolysis 60

AHIMA 2009 Audio Seminar Series 30 Coding for Hematology Notes/Comments/Questions

Coding – Secondary Hypercoagulable State (289.82) Derived conditions leading to tendency to make clots at undesirable times Š Lupus anticoagulant syndrome Š Malignancies, especially pancreas Š Myeloproliferative disorders Š Paroxysmal nocturnal hemoglobinuria Š Pregnancy Š Nephrotic syndrome Š Inflammatory bowel disease (Crohn’s) Š Drug-related 61

Coding – HIT - Heparin-Induced Thrombocytopenia (289.84)

Š Distinct, relatively common life-threatening clinical condition occurring in 3-5% of all patients receiving unfractionated heparin for at least 5 days. Š Totally different clinical picture from other drug-induced thrombocytopenias. • Presents with arterial or venous thrombosis (DVT, PE, stroke, MI) • Transfusion of platelets generally contraindicated • Patients require therapeutic doses of alternative anticoagulant 62

AHIMA 2009 Audio Seminar Series 31 Coding for Hematology Notes/Comments/Questions

Coding Clinic Reference

Š Heparin-Induced Thrombocytopenia (HIT) CC 4th Qtr 2008, pg 100-101 Š Remember there can be documented Heparin Induced Thrombocytopenia with Thrombosis! (HITT) – same code

63

Procedure Issues in Hematology

Š Bone marrow biopsy/aspiration • ICD-9-CM: 41.31 - same code for both biopsy and aspiration of bone marrow • CPT: • 38220 – bone marrow aspiration only • 38221 – bone marrow biopsy, needle or trocar • HCPCS: G0364 (temporary) - Bone marrow aspiration performed with bone marrow biopsy through the same incision on the same date of service 64

AHIMA 2009 Audio Seminar Series 32 Coding for Hematology Notes/Comments/Questions

CPT® Assistant Reference

Š Bone Marrow Biopsy, Bone Marrow Aspiration, and Bone Biopsy, July 1998, Volume 08, Issue 7, pages 4-7

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Bone Marrow Aspiration (38220)

Š May be performed independent of bone marrow biopsy or may immediately follow a biopsy Š Evaluates cellular population not the alteration of cells due to disease Š Following penetration of bone cortex, syringe is attached to the needle and fluid aspirated

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AHIMA 2009 Audio Seminar Series 33 Coding for Hematology Notes/Comments/Questions

Procedure: Bone Marrow Aspiration

Close-up of technique used to obtain bone marrow sample by aspiration through a needle.

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Bone Marrow Biopsy (38221)

Š Evaluates • Presence and relative quantification of abnormal cells (lymphoma, leukemia, etc.) • Relative abundance of normal marrow cells • Presence of tumor metastasis • Presence of myelofibrosis

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AHIMA 2009 Audio Seminar Series 34 Coding for Hematology Notes/Comments/Questions

Procedure: Bone Marrow Biopsy

Posterior view of pelvic region with target area for bone marrow biopsy highlighted. Posterior view of pelvis with hypodermic needle penetrating skin at an angle to reach the ilium just below the iliac crest. Needle slowly advanced with twisting motion. After penetration of bone, needle/trocar is rotated several times, withdrawn several millimeters, then reinserted to the original depth at a slightly different angle. Rotated again, then withdrawn using the same twisting motion used during insertion. 69

Bone Marrow Aspiration (38220) vs. Biopsy (38221)

Aspiration Biopsy Š Retrieving fluid Š Retrieving from bone marrow cancellous bone Š Obtained via Š Obtained via needle (University needle (e.g. of Illinois) Jamshidi) or trocar Š Does not produce Š Produces core of intact tissue intact marrow

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AHIMA 2009 Audio Seminar Series 35 Coding for Hematology Notes/Comments/Questions

Resource/Reference List

Š National Center for Health Statistics; ICD-9- CM Coordination and Maintenance Committee: http://www.cdc.gov/nchs/about/otheract/icd9/maint/maint.htm Š ASH http://www.hematology.org Š ICD-9-CM Official Coding Guidelines for Coding and Reporting http://www.cdc.gov/nchs/datawh/ftpserv/ftpicd9/icdguide08.pdf Š AHA Coding Clinics Š Coder’s Desk Reference

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Audio Seminar Discussion

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AHIMA 2009 Audio Seminar Series 36 Coding for Hematology Notes/Comments/Questions

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AHIMA 2009 Audio Seminar Series 37 Coding for Hematology Notes/Comments/Questions

Upcoming Seminars/Webinars

Coding for Multi-System Trauma Patients April 9, 2009 Effective Denials Management April 16, 2009 Procedure Coding for Skin Lesions and Lacerations April 30, 2009

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AHIMA 2009 Audio Seminar Series 38 Appendix

Resource/Reference List ...... 40 CE Certificate Instructions

AHIMA 2009 Audio Seminar Series 39

Appendix

Resource/Reference List

http://www.cdc.gov/nchs/datawh/ftpserv/ftpicd9/icdguide08.pdf

http://www.cdc.gov/nchs/about/otheract/icd9/maint/maint.htm

http://www.hematology.org

AHIMA 2009 Audio Seminar Series 40

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