Anti-PPP3CA monoclonal antibody, clone DO-C2 (DCABH-8962) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to B

Antigen Description Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated phosphatase. Confers calcium sensitivity.

Specificity This antibody recognises the beta subunit of calcineurin. It does not cross-react with the alpha subunit of calcineurin.

Immunogen Purified bovine brain calcineurin preparation.

Isotype IgM

Source/Host Mouse

Species Reactivity Rat, Cow, Human

Clone DO-C2

Purity Ascites

Conjugate Unconjugated

Applications WB, ELISA, IHC-P

Positive Control Rat brain extract

Format Liquid

Size 100 μl

Buffer Preservative: 15mM Sodium Azide; Constituents: Ascites

Preservative 15mM Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

GENE INFORMATION

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Name PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme [ Bos taurus ]

Official Symbol PPP3CA

Synonyms PPP3CA; protein phosphatase 3, catalytic subunit, alpha isozyme; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; calcineurin A alpha; CAM-PRP catalytic subunit; calmodulin-dependent calcineurin A subunit alpha isoform; protein pho

Entrez Gene ID 286852

Protein Refseq NP_777212

UniProt ID P48452

Pathway Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem;

Function calmodulin binding; calmodulin-dependent protein phosphatase activity; hydrolase activity; metal ion binding; phosphoprotein phosphatase activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved