SYMPK Cat. No.: 25-800

SYMPK Antibody

Antibody used in IHC on Human HT29 at 1:50.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human SYMPK.

TESTED APPLICATIONS: ELISA, WB

SYMPK antibody can be used for detection of SYMPK by ELISA at 1:1562500. SYMPK APPLICATIONS: antibody can be used for detection of SYMPK by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

PREDICTED MOLECULAR 141 kDa WEIGHT:

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PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: SYMPK antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: SYMPK

ALTERNATE NAMES: SYMPK, FLJ27092, SPK, SYM

ACCESSION NO.: NP_004810

PROTEIN GI NO.: 124028529

GENE ID: 8189

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

SYMPK is a nuclear that functions in the regulation of polyadenylation and promotes expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.This gene encodes a nuclear protein that functions in the regulation of polyadenylation and BACKGROUND: promotes . The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

REFERENCES: 1) Cao, Y., (2007) Histopathology 51 (4), 528-538.

ANTIBODIES FOR RESEARCH USE ONLY.

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