SYMPK Antibody Cat. No.: 25-800
SYMPK Antibody
Antibody used in IHC on Human HT29 at 1:50.
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human SYMPK.
TESTED APPLICATIONS: ELISA, WB
SYMPK antibody can be used for detection of SYMPK by ELISA at 1:1562500. SYMPK APPLICATIONS: antibody can be used for detection of SYMPK by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL: 1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
PREDICTED MOLECULAR 141 kDa WEIGHT:
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PURIFICATION: Antibody is purified by peptide affinity chromatography method.
CLONALITY: Polyclonal
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.
CONCENTRATION: batch dependent
For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: SYMPK antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Additional Info
OFFICIAL SYMBOL: SYMPK
ALTERNATE NAMES: SYMPK, FLJ27092, SPK, SYM
ACCESSION NO.: NP_004810
PROTEIN GI NO.: 124028529
GENE ID: 8189
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.This gene encodes a nuclear protein that functions in the regulation of polyadenylation and BACKGROUND: promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
REFERENCES: 1) Cao, Y., (2007) Histopathology 51 (4), 528-538.
ANTIBODIES FOR RESEARCH USE ONLY.
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