Drg 04.11.11 12:26 Seite 1

Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:26 Seite 1

Product Information Produktinformation 2012/2013 DRG Notes for catalogue users: Red marked immunoassays on pages 13 - 53 are ELISAS. Black marked kits are radioimmunoassays (RIAS). Yellow marked kits are chemiluminescence immunoassays (CLAS). Green highlighted assays are RIAS or ELISAS suitable for samples from other species (e. g. rat, mouse, porcine, etc.)

Hinweis zur Katalogbenutzung: Bei den “rot” markierten Immunoassays auf den Seiten 13 bis 53 handelt es sich um ELISAS, die “schwarz” markierten sind Radioimmunoassays (RIAS), die “gelb” markierten sind Chemilumineszenz Immunoassays (CLAS). Bei den “grün” hinterlegten Assays handelt es sich um RIAS oder ELISAS zur Bestimmung von Proben anderer Spezies (Ratte, Maus, Schwein usw.)

This edition succeeds all former product lists, which are no longer valid.

Mit Erscheinen dieser Ausgabe verlieren alle vorherigen Produktinformationen ihre Gültigkeit. Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 2

ELISAS that perform

Saliva Diagnostics Diabetes Immunology Gynecologic Endocrinology Prenatal Supervision Tumor Marker Hematology Iron Metabolism Infectious Diseases

Quality DRG works to EN ISO 9001:2008, EN ISO 13485:2003 + AC:2007 standard, certified by TÜV Rheinland Product Safety NEW/Neu ELISAS GmbH, an indication of our commitment to customer service, quality control and Amyloid Beta 1-40 (Serum) improved health care. • Amyloid Beta auto-Ab (Serum) We participate in a number of quality • assessment schemes, which include • 25-OH Vitamin D (total) Instand (Germany) and RfB, Referenz- institut für Bioynalytik, Bonn. • L1-CAM CYR 61 (Cardiac) DRG products meet the essential • requirements of the directive 98/79/EC • NOV of 27. October 1998 on in-vitro diagnostic medical devices. • Renin • Aldosteron • ER-60 (Male Infertility) Benefits • CTGF Simple protocols and room • Afamin temperature incubations reduce errors and technician time. Automatible. • Estrone (improved) Estrone Saliva Versatile. Compatible with most • available equipment.

Added confidence in results. NEW/Neu Assured continuity of supply. Tumormarker Control of production methods results in economic prices. • TM-CA 15-3 TM-CA 125 Microtiter Wells - Breakable • Long shelf life • TM-CA 19-9 Good correlation to RIA’S • TM-CA 72-4 Direct determination TM-CYFRA 21-1 Specific • Convenient and economical Easy to use Fast Sensitive

Diagnostics 2 Preisliste aktuell 10.2011_B+F_Preisl. 2006_04 o.Preis_drg 07.11.11 10:13 Seite 3

DRG ELISAS / EN ISO 9001/13485

DRG-ELISAS Qualität

Einfache Testabläufe bei Raumtemperatur Mikrotiterstrips einzeln brechbar Das DRG Qualitätsmanagement-System reduzieren Fehler bei der Abarbeitung. nach EN ISO 9001:2008, EN ISO 13485:2003 Lange Haltbarkeit + AC:2007 und ISO 13485:2003 CMDCAS DRG ELISAS sind kompatibel zu sämtli- (mind. 12 Monate bei 2-8°C) zertifiziert vom TÜV Rheinland, garantiert eine chen marktgängigen MTPL-Photometern Direkte Bestimmung gleichbleibende, ständig kontrollierte Produkt- und MTPL-Vollautomaten. qualität. Hohe Spezifität und Sensitivität Gleichbleibende, kontrollierte Qualität Zuverlässige Ergebnisse gewährleisten zuverlässige Ergebnisse. Gute Korrelationen mit etablierten RIAS Verbraucherfreundliche Preise bei schnel- Anwenderfreundlich und ökonomisch ler Lieferung gewährleisten eine ökonomi- sche Durchführung. Schnell

Zur Überprüfung und Sicherstellung der Produktqualität nehmen wir regelmäßig an externen Qualitätskontrollen wie z.B. den Ringversuchen der RfB, Referenzinstitut für Bioanalytik in Bonn sowie INSTAND in Düsseldorf teil. Viele DRG Produkte erfül- len die Anforderungen der EU-Richtlinien 98/79/EC vom 27.10.1998 für In-Vitro-Diagnostika (IVD’s) und sind mit dem CE Zeichen gekennzeichnet.

Vollautomatischer Random Access Analyzer für Immunoassays und Klinische Chemie Fully automated Random Access Analyzer for the simultaneous measurement of Immunoassays and Clinical Chemistry

Available Spring 2012

Ab Frühjahr 2012 verfügbar!

ELISAS that perform 3 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 4

Product Groups / Table of Contents Page 6 • Fully automated Random Access Analyzer for Immunoassays and Clinical Chemistry Radioimmunoassays (RIAS) Enzyme Immunoassays (ELISAS) Chemiluminescence Immunoassays (CLAS)

Autoimmune Diseases 13 Chemiluminescence Immunoassays (CLAS) 16 Diabetes/Gastrointestinal and Pankreatic 17 Drug Monitoring 22 Endocrinology 23 Fertility and Pregnancy 27 Pituitary / Adrenal Function 31 Immunology/Hematology 32 Cardiovascular Diseases 37 Bone and Mineral Metabolism 39 Leukotrienes and Prostaglandins 41 Neuropeptides 42 Thyroid Function 43 Saliva Diagnostics 44 Oncology/Tumor Diagnosis 45 Infectious Diseases 47 Vitamines 52 Growth Factors 53 Equipment: Fully automated Analyzer, Reader, Washer MTPL-Reader, Washer, Incubator/Shaker, Fully Automated MTPL-Analyzer 54 • E-Lizamat 8882/8884 55 • E-Lizamat GS (ELM GS) 57

Disposables for laboratory use 58 Controls 59 Veterinary Diagnostics Immunoassays/Rapid Screen Tests 60 Rapid Screen Tests 63 TOXI-LAB® Drug Identification System 65

Extraction Supplies 79 Index/Abbreviations/DRG Group 84

4 Product Groups Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 5

Produktübersicht / Inhaltsverzeichnis Seite 6 • Vollautomatischer Random Access Analyzer für Immunoassays und klinische Chemie Radioimmunoassays (RIAS) Enzymimmunoassays (ELISAS) Chemilumineszenz-Immunoassays (CLAS)

Autoimmunerkrankungen 13 Chemilumineszenz-Immunoassays (CLAS) 16 Diabetes/Gastrointestinal und Pankreas 17 Drogen- und Arzneimittelspiegel 22 Endokrinologie 23 Fertilität und Schwangerschaft 27 Funktion der Hypophysen-Nebennierenrindenachse 31 Immunologie/Hämatologie 32 Kardiovaskuläre Erkrankungen 37 Knochen- und Mineralstoffwechsel 39 Leukotriene und Prostaglandine 41 Neuropeptide 42 Schilddrüsenfunktion 43 Speichel Diagnostik 44 Tumordiagnostik/Onkologie 45 Virologie/Serologie 47 Vitamine 52 Wachsstumsfaktoren 53

Geräte: Vollautomaten, Photometer, Wascher 54 MTPL-Photometer, Waschgerät, Inkubator, ELISA Vollautomat (offene Systeme) • E-Lizamat 8882/8884 55 • E-Lizamat GS (ELM GS) 57 Laborbedarf 58 Kontrollen 59 Veterinärmedizinische Diagnostika Immunoassays/Schnelltests 60 Schnelltests 63

TOXI-LAB® Drogenidentifikations-System 65

Extraktion 79

Stichwortverzeichnis/Abkürzungen/Serviceleistungen/ 84 Geschäftsbedingungen/DRG Niederlassungen Produktübersicht 5 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 6

Available Spring 2012

Ab Frühjahr 2012 verfügbar!

6 Equipment Configuration Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 7

Equipment Configuration 7 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 8

8 Equipment Configuration Preisliste aktuell 10.2011_B+F_Preisl. 2006_04 o.Preis_drg 04.11.11 15:03 Seite 9

Equipment Configuration 9 Preisliste aktuell 10.2011_B+F_Preisl. 2006_04 o.Preis_drg 04.11.11 15:03 Seite 10

10 Equipment Configuration Preisliste aktuell 10.2011_B+F_Preisl. 2006_04 o.Preis_drg 04.11.11 15:03 Seite 11

Immunoassays 11 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 12

ELISA’S (Enzyme Immunoassays) RIA’S (Radioimmunoassays) CLA’S (Chemiluminescence Immunoassays)

Benefits Simple protocols and room NEW/Neu ELISAS temperature incubations reduce errors and technician time. Automatible. • Amyloid Beta 1-40 (Serum) Versatile. Compatible with most • Amyloid Beta auto-Ab (Serum) available equipment. • 25-OH Vitamin D (total) Added confidence in results. • L1-CAM Assured continuity of supply. CYR 61 (Cardiac) Control of production methods • results in economic prices. • NOV Microtiter Wells - Breakable • Renin Long shelf life • Aldosteron Good correlation to RIA’S • ER-60 (Male Infertility) Direct determination CTGF Specific • Convenient and economical • Afamin Easy to use • Estrone (improved) Fast Estrone Saliva Sensitive • NEW/Neu Tumormarker • TM-CA 15-3 ELISAS that perform • TM-CA 125 • TM-CA 19-9 • TM-CA 72-4 • TM-CYFRA 21-1

Saliva Diagnostics Diabetes Immunology Gynecologic Endocrinology Prenatal Supervision Tumor Marker Hematology Iron Metabolism Infectious Diseases

12 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 13

Autoimmune Diseases New/Neu: Cartilage Oligomeric Matrix Protein Blots: Amyloid Beta Auto Ab ELISA ANA Anti CCP2 ELISA ANCA Acetylcholine Receptor Ab ELISA Gastro Screen S100 A8 / S100 A9 (rat/mouse) ELISA Liver Screen Rheumatoid Arthritis: Myositis Screen ACPA (Anti-Citrunillated Protein Ab) ELISA Nucleo Screen

Product / Method Cat No. No. of Tests Incubation time

Acetylcholin Receptor (AChR) Ab ELISA EIA-4936 96 Wells overnight/60/60/30/30 min Acetylcholin-Rec. Auto-Ab RRA RIA-2956 100 Tests 120/30 min ACPA (anti Citrullinated Protein Ab) EIA-4848 96 Wells 30/15/15 min AMA-M2 ELISA (anti-Mitochondrial Ab) EIA-3604 96 Wells 30/15/15/5 min Amyloid Beta Auto-Ab ELISA EIA-5099 96 Wells 60/30/20 min anti-Alpha-Fodrin ELISA EIA-3978 96 Wells 30/15/15/5 min ANA Screen Blot DOT-5113 16 Strips 5/60/30/10 min ANA Screen Blot DOT-5114 8 Strips 5/60/30/10 min ANA Screen Blot DOT-5115 8 Strips 5/60/30/10 min ANA Screen Blot DOT-5116 16 Strips 5/60/30/10 min ANA Screen ELISA EIA-3562 96 Wells 30/15/15/5 min ANA Combi ELISA EIA-3563 96 Wells 30/15/15/5 min ANA Detect ELISA EIA-4117 96 Wells 30/15/15 min ANCA Screen ELISA EIA-3776 96 Wells 30/15/15/5 min anti- PR-3 (c-ANCA) ELISA EIA-3596 96 Wells 30/15/15/5 min anti-MPO (p-ANCA) ELISA EIA-3597 96 Wells 30/15/15/5 min anti-Annexin V IgG/IgM ELISA EIA-3971 96 Wells 30/15/15/5 min ASCA IgA ELISA EIA-4279 96 Wells 60/30/10 min ASCA IgG ELISA EIA-4280 96 Wells 60/30/10 min anti-ASGPR ELISA EIA-4271 96 Wells 60/30/10 min anti-BPI ELISA EIA-3598 96 Wells 30/15/15/5 min Carbonylprotein ELISA EIA-5141 96 Wells 3 h/20/20/20 min New Cartilage Oliomeric Matrix Protein (Human) ELISA EIA-5265 96 Wells 60/60/30/10 min anti-Cardiolipin IgA ELISA EIA-3588 96 Wells 30/15/15/5 min anti-Cardiolipin IgG/IgM ELISA EIA-3587 96 Wells 30/15/15/5 min anti-Cardiolipin Screen EIA-3589 96 Wells 30/15/15/5 min anti-Cathepsin G ELISA EIA-3600 96 Wells 30/15/15/5 min anti-Centromer B ELISA EIA-3569 96 Wells 30/15/15/5 min anti CCP2 ELISA EIA-5134 96 Wells 60/30/15 min anti-dsDNA IgG ELISA EIA-3438 96 Wells 30/15/15/5 min anti-dsDNA IgM ELISA EIA-3564 96 Wells 30/15/15/5 min anti-dsDNA IgA ELISA EIA-3565 96 Wells 30/15/15/5 min anti-dsDNA Screen ELISA EIA-3566 96 Wells 30/15/15/5 min anti-ssDNA ELISA EIA-3567 96 Wells 30/15/15/5 min

Immunoassays 13 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 14

Autoimmunerkrankungen

Product / Method Cat No. No. of Tests Incubation time

anti-Elastase ELISA EIA-3599 96 Wells 30/15/15/5 min ENA Screen ELISA EIA-3571 96 Wells 30/15/15/5 min ENA Combi ELISA EIA-3572 96 Wells 30/15/15/5 min ENA-6-Profile ELISA EIA-3901 96 Wells 30/15/15/5 min ENA-4-Profile ELISA EIA-3977 4 x 24 Tests 30/15/15/5 min ENA Profile-8 ELISA EIA-4325 96 Wells 30/30/30 min. ENA Screen-6 ELISA EIA-4326 96 Wells 30/30/30 min. anti-GAD65 RLA RIA-2057 100 Tests 120/60/20 min GAD 65 Ab ELISA EIA-4087 96 Wells 60/60/20/20 min anti-GAD ELISA EIA-1910 96 Wells 60/60/30 min Gastro Screen Blot DOT-5117 8 Strips 5/60/30/10 min Gastro Screen Blot DOT-5118 16 Strips 5/60/30/10 min anti-GBM ELISA EIA-3603 96 Wells 30/15/15/5 min Gliadin-Ab IgA ELISA EIA-4069 96 Wells 30/30/30 min Gliadin-Ab IgG ELISA EIA-4070 96 Wells 30/30/30 min Gliadin Screen ELISA EIA-4465 96 Wells 30/15/15 min anti-Beta2 Glycoprotein I IgG/IgM ELISA EIA-3590 96 Wells 30/15/15/5 min anti Beta2 Glycoprotein IgA EIA-3884 96 Wells 30/15/15/5 min anti-Beta2 Glycoprotein I Screen ELISA EIA-3911 96 Wells 30/15/15/5 min HepAK Dot DOT-4274 96 (24x4) Tests 30/30/10 min HepAK plus Dot DOT-4275 120 (24x5) Tests 30/30/10 min anti-Histone ELISA EIA-3568 96 Tests 30/15/15/5 min 21 Hydroxylase Ab RIA RIA-4244 50 Tests Overnight/60/30 min 21-Hydroxylase Ab RIA RIA-4430 100 Tests Overnight/60/30 min anti-IA2 RLA RIA-3761 50 Tests 18 h/30 min IA-2 Ab ELISA EIA-4088 96 Wells 60/60/20/20 min ICA 2-Screen ELISA EIA-4253 96 Wells Overnight/60/20 min ICA (Isle-Cell Autoantibody) ELISA EIA-1594 96 Wells 60/60/30 min Intrinsic Factor ELISA EIA-4392 96 Wells 30/15/15 min anti-Insulin Ab ELISA EIA-3608 96 Wells 30/15/15/5 min anti-Jo-1 IgG ELISA EIA-3581 96 Wells 30/15/15/5 min anti-Lysozyme ELISA EIA-3601 96 Wells 30/15/15/5 min anti-Lactoferrin ELISA EIA-3602 96 Wells 30/15/15/5 min Anti-LC-1 ELISA EIA-4276 96 Wells 30/15/15 min Liver Screen Blot DOT-5119 8 Strips 5/60/30/10 min Liver Screen Blot DOT-5120 16 Strips 5/60/30/10 min Anti-LKM-1 ELISA EIA-4277 96 Wells 30/15/15 min anti-ß2-Microglobulin I ELISA EIA-3609 96 Wells 30/15/15/5 min Myositis Screen Blot DOT-5121 8 Strips 5/60/30/10 min

14 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 15

Autoimmune Diseases

Product / Method Cat No. No. of Tests Incubation time

Myositis Screen Blot DOT-5122 16 Strips 5/60/30/10 min Nucleo Screen Blot DOT-5123 8 Strips 5/60/30/10 min Nucleo Screen Blot DOT-5124 16 Strips 5/60/30/10 min anti-Nucleosomes (SLE) ELISA EIA-3610 96 Wells 30/15/15/5 min Anti-Ovarian Ab ELISA EIA-2937 96 Wells 60/60/30 min anti-Parietal Cell ELISA EIA-3607 96 Wells 30/15/15/5 min anti-Phosphatidyl Serine IgG/IgM ELISA EIA-3592 96 Wells 30/15/15/5 min anti-Phosphatidyl Inositol IgG/IgM ELISA EIA-3593 96 Wells 30/15/15/5 min anti-Phosphatidic Acid IgG/IgM ELISA EIA-3594 96 Wells 30/15/15/5 min anti-Phospholipid Screen IgG/IgM ELISA EIA-3591 96 Wellls 30/15/15/5 min anti-Prothrombin IgG/IgM ELISA EIA-3612 96 Wells 30/15/15/5 min anti-Prothrombin IgA ELISA EIA-3613 96 Wells 30/15/15/5 min anti-Prothrombin Screen ELISA EIA-3614 96 Wells 30/15/15/5 min Rheumatoid Factor IgM ELISA EIA-2005 96 Wells 30/30/10 min Rheumatoid Factor Screen ELISA EIA-3583 96 Wells 30/15/15/5 min Rheumatoid Factor IgG ELISA EIA-3584 96 Wells 30/15/15/5 min Rheumatoid Factor IgA ELISA EIA-3586 96 Wells 30/15/15/5 min Rheumatoid Factor IgM ELISA EIA-3585 96 Wells 30/15/15/5 min anti-Rib-P ELISA (anti Ribosomal P) EIA-3582 96 Wells 30/15/15/5 min anti-RNP/Sm ELISA EIA-3578 96 Wells 30/15/15/5 min anti-RNP-70 Kd ELISA EIA-3579 96 Wells 30/15/15/5 min S100A8/S100A9 (Mouse/Rat) ELISA EIA-5142 96 Wells 60/60/60/5-15 min anti-Scl-70 ELISA EIA-3580 96 Wells 30/15/15/5 min anti-Sm ELISA EIA-3577 96 Wells 30/15/15/5 min anti-SS-A (Ro) ELISA EIA-3573 96 Wells 30/15/15/5 min anti-SS-A 52 ELISA EIA-3574 96 Wells 30/15/15/5 min anti-SS-A 60 ELISA EIA-3575 96 Wells 30/15/15/5 min anti-SS-B (La) ELISA EIA-3576 96 Wells 30/15/15/5 min Secretory IgA ELISA EIA-4601 96 Wells 60/60/5-15 min Sperm Antibody (seminal fluid) ELISA EIA-1826 96 Wells 60/60/30 min Thrombo-Combo IgG/IgM ELISA EIA-3883 96 Wells 30/15/15/5 min Thyroglobulin Ag ELISA EIA-3377 96 Wells 60/60/15/5 min TG Ab (Thyroglobulin Ab) ELISA EIA-3708 96 Wells 30/15/15/5 min TPO Ab (Thyr. Perox. Ab) ELISA EIA-3561 96 Wells 30/15/15/5 min anti Translutaminase Screen EIA-4464 96 Wells 30/15/15 min Transglutaminase IgA ELISA EIA-3611 96 Wells 30/15/15/5 min Transglutaminase IgG ELISA EIA-3882 96 Wells 30/15/15/5 min Transglutaminase IgA ELISA EIA-4259 96 Wells 30/30/30 min Transglutaminase IgG ELISA EIA-4260 96 Wells 30/30/30 min TSH Receptor Autoantibody ELISA (2nd generation) EIA-3369 96 Wells 120/20/20/20 min TSH Receptor Autoantibody ELISA (3rd generation) EIA-4834 96 Wells 120/25 min Immunoassays 15 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 16

Chemiluminescence Immunoassays

Advantages of the DRG New/Neu: Chemiluminescence Immunoassays: CYFRA 21-1 • Super sensitive • Safe and efficient CA 72-4 • Elongated standard curves • Direct determination Prolactin • Short incubation times • Long shelf life Toxo IgG/IgM • Simple and reliable Rubella IgG/IgM HSV 1 IgM

Product / Method Cat No. No. of Tests Incubation time

Aldosterone (Serum) CLA CLA-4650 96 Wells Androstanediol Glucuronide (3a Diol G) CLA CLA-4649 96 Wells CA 72-4 (Serum) CLA CLA-4730 96 Wells Cortisol (Serum) CLA CLA-4666 96 Wells CYFRA 21-1 (Serum) CLA CLA-4731 96 Wells DHEA-S (Serum) CLA CLA-4652 96 Wells Estradiol (Serum) CLA CLA-4664 96 Wells Free Estriol (Salivary) CLA CLA-4653 96 Wells Estrone (Salivary) CLA CLA-4655 96 Wells HSV1 IgM CLA-available soon 96 Wells Progesterone (Serum) CLA CLA-4663 96 Wells 17 OH Progesterone (Serum) CLA CLA-4665 96 Wells Prolactin (Serum) CLA CLA-4729 96 Wells PSA total (Serum) CLA CLA-4657 96 Wells Rubella IgG CLA-availabel soon 96 Wells Rubella IgM CLA-available soon 96 Wells Testosterone (Serum) CLA CLA-4662 96 Wells Testosterone (Salivary) CLA CLA-4661 96 Wells Free Testosterone (Serum) CLA CLA-4660 96 Wells Toxo IgG CLA-available soon 96 Wells Toxo IgM CLA-available soon 96 Wells T4 free (Serum) CLA CLA-4659 96 Wells TSH (Serum) CLA CLA-4658 96 Wells

16 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 17

Diabetes/Gastrointestinal and Pancreatic New/Neu: Animal Insulin ELISAS Adiponectin ELISA Insulin (Feline) (Bovine, Canine, Equine, Ovine, Porcine) Alpha Amylase (Saliva) Leptin Receptor ELISA - Species specific optimized assays Calprotectin Leptin (Rat) ELISA - Monoclonal antibodies (MRP 8/14) ELISA Pepsinogen I/II ELISAS C-Peptide (Rat) ELISA Proinsulin (rat/mouse) ELISA Histamin Intolerance: Ghrelin Visfatin ELISAS DAO active ELISA unacylated ELISA

Product / Method Cat No. No. of Tests Incubation time

Adiponectin (Human) ELISA EIA-4177 96 Wells 120/30/5-10 min Adiponectin (Human) ELISA EIA-4574 96 Wells 120/10 min Adiponectin (Human) (DA) RIA RIA-3765 125 Tests 20-24h/20 min Adiponectin (Human) ELISA EIA-4177 96 Wells 120/10 min Adiponectin (Human) ELISA EIA-4646 96 Wells 60/60/15 min Adiponectin (Human) ELISA EIA-4820 96 Wells 90/30/20 min

Adiponectin Human High Molecular Weight (HMW) ELISA EIA-4645 96 Wells 120/60/30/5-20 min Adiponectin (Mouse) ELISA EIA-4553 96 Wells 60/60/10 min Adiponectin (Mouse) ELISA EIA-4172 96 Wells 120/30/15 min Adiponectin (Mouse/Rat) (DA) RIA RIA-3766 125 Tests 20-24h/20 min Adiponectin Rat ELISA EIA-4570 96 Wells 120/60/30/5-25 min Alpha Amylase Saliva ENZ-5127 96 Wells 3 min Amylase ELISA EIA-4460 96 Wells 30/15 min Amylin (Human) ELISA EIA-3742 96 Wells 10/60/120/20 min Amylin total (Human) ELISA EIA-3741 96 Wells 10/60/120/20 min Animal Insulin Control CTL-4784 3 x 0.5 ml Bombesin (DA) RIA* RIA-0666 125 Tests 16-24/16-24h/90 min Calprotectin Stool ELISA EIA-5190 96 Wells 60/60/10-20 min Calprotectin (MRP 8/14) Blood/Urine ELISA EIA-5111 96 Wells 60/60/60/10-20 min CCK (Cholecystokinin) RIA RIA-4118 100 Tests 2h/4h/60 min C-Peptide (Porcine) (DA) RIA RIA-1256 250 Tests 20-24/20-24h/20 min C-Peptide (Human) (DA) RIA RIA-1252 250 Tests 20-24h/20 min C Peptide (Rat) (DA) RIA RIA-1254 250 Tests 20-24/20-24h/20 min C-Peptide (Canine) (DA) RIA RIA-2953 125 Tests 20-24/20-24h/20 min C-Peptide ELISA EIA-1293 96 Wells 5 min/3 h/60/30 min C-Peptide (Rat) ELISA EIA-4767 96 Wells 60/60/15 min C-Peptide IRMA RIA-4383 96 Tests 3h C-Peptide RIA RIA-1628 100 Tests 4h C-Peptide RIA (cubic size) RIA-4382 384 Tests 3h C-Peptide RIA RIA-4383 96 Tests 3h

Immunoassays 17 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 18

Diabetes/Gastrointestinal und Pankreas

Product / Method Cat No. No. of Tests Incubation time

Cortistatin-29 (Human) (DA) RIA* RIA-2129 125 Tests 16-24/16-24h/90 min Cholecystokinin (CCK) ELISA EIA-4393 96 Wells 2h/1h/1h New DAO ELISA EIA-5240 96 Wells 120/60/60/10-20 min Diabetes-antigen Control (Human) CTL-5132 2x0.5 ml Endostatin (Human) ELISA EIA-4552 96 Wells 60/60/10 min anti GAD ELISA EIA-1910 96 Wells 60/60/30 min GAD 65 Ab ELISA EIA-4087 96 Wells 60/60/20/20 min GAD-65, anti RIA RIA-4598 50 Tests 120/60/20 min Gastrin (DA) RIA RIA-1987 100 Tests 120/15 min Big Gastrin (DA) RIA* RIA-0670 125 Tests 16-24/16-24h/90 min Gastrin ELISA EIA-4187 96 Wells 2/3h Gastrin (Rat) ELISA EIA-4501 96 Wells 2h/3h Gastrin Releas. Pept. (Human) (DA) RIA* RIA-1137 125 Tests 16-24/16-24h/90 min Ghrelin Active ELISA EIA-4710 96 Wells 120/30/15 min Ghrelin Total ELISA EIA-4709 96 Wells 120/30/25 min Ghrelin (acylated) human EIA-4686 96 Wells 3 h/30-60 min Ghrelin (Active) (DA) RIA RIA-3966 125 Tests 20-24/20-24h/20 min Ghrelin (Total) (DA) RIA RIA-3967 125 Tests 20-24/20-24h/20 min Ghrelin (Rat) (DA) RIA* RIA-3546 125 Tests 16-24/16-24h/90 min Ghrelin, Prepro- (Human) (DA) RIA* RIA-3547 125 Tests 16-24/16-24h/90 min New Ghrelin unacylated (Human) ELISA EIA-5257 96 Wells 180/30 min GIP (Gastr. Inhibit. Pept.) (DA) RIA* RIA-0669 125 Tests 16-24/16-24h/90 min GIP (Human) ELISA EIA-4527 96 Wells 90/60/30/20 min GIP (Rat/Mouse) ELISA EIA-4528 96 Wells 90/30/30/18 min GLP-1 total ELISA EIA-5095 96 Wells 20-24h/20 min GLP-1 active ELISA EIA-5096 96 Wells 20-24h/20 min GLP-2 (Human) ELISA EIA-4474 96 Wells overnight/60/30 min GLP-2 (Mouse) ELISA EIA-4476 96 Wells overnight/60/30 min GLP-2 (Rat) ELISA EIA-4478 96 Wells overnight/60/30 min Glicentin (Rat) ELISA EIA-4477 96 Wells overnight/60/30 min Glucagone like Peptide I (total) (DA) RIA RIA-3000 125 Tests 20-24/22-24h/20 min Glucagone like Peptide I (active) (DA) RIA RIA-3001 125 Tests 20-24/22-24h/20 min Glucagone (DA) RIA RIA-0226 50 Tests 6/16 h Glucagon (Rat, Mouse, Human) ELISA EIA-4475 96 Wells overnight/60/20 min Gluc. like Peptide I (active) ELISA (see next line) EIA-3056 96 Wells 20-24h/5 min/2h/20 min DPP-IV, Protease Inhibitor for Gluc. Like Pept. DPP-4 1 ml Glucagone (Pankreas – spec.) (DA) RIA RIA-1258 250 Tests 20-24/20-24h/20 min Glucagone-like Pept.-1 (7-37) (Human) (DA) RIA* RIA-1139 125 Tests 16-24/16-24h/90 min Glucagone-like Peptide-2 (Human) (DA) RIA* RIA-1649 125 Tests 16-24/16-24h/90 min

18 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 19

Diabetes/Gastrointestinal and Pancreatic

Product / Method Cat No. No. of Tests Incubation time

anti-IA2 RLA (former RIA-2086) RIA-3761 50 Tests 18h/30/20 min IAA RIA RIA-4264 50 Tests 16-24h/1h IAA RIA RIA-4265 100 Tests 16-24h/1h IAA ELISA EIA-1593 96 Wells overnight/60/30 min ICA (Isle-Cell Autoantibody) ELISA EIA-1594 96 Wells 60/6030 min ICA 2-Screen ELISA EIA-4253 96 Wells Overnight/60/20 min Insulin (Hum. Insulin spec.) (DA) RIA RIA-1249 250 Tests 24h/20 min Insulin (Human) Ultrasensitive (DA) RIA RIA-1255 250 Tests 18-24/24h/20 min Insulin (Human) (DA) RIA RIA-1435 100 Tests 18 h Insulin IRMA (cubic size) RIA-4375 384 Tests 2h Insulin (Human) IRMA RIA-4376 96 Tests 2h Insulin (Human) ELISA EIA-2935 96 Wells 30/30/15 min Insulin (Human) ELISA EIA-1825 96 Wells 60/15 min Insulin (Human) Ultrasensitive ELISA EIA-2337 96 Wells 60/15 min Insulin, Iso-, ELISA EIA-2336 96 Wells 60/15 min Insulin, Lispro-, (DA) RIA RIA-2923 125 Tests 24h/20 min Insulin (Bovine) ELISA EIA-4748 96 Wells 120/15 min Insulin (Canine) ELISA EIA-4749 96 Wells 120/15 min Insulin (Equine) ELISA EIA-4746 96 Wells 120/15 min Insulin (Mouse) ELISA EIA-3439 96 Wells 120/15 min Insulin (Mouse) Ultrasensitive ELISA EIA-3440 96 Wells 120/30 min Insulin (Porcine) (DA) RIA RIA-1257 250 Tests 18-24 h Insulin (Porcine) ELISA EIA-4747 96 Wells 120/15 min Insulin (Porcine) High Range ELISA EIA-5126 96 Wells 60/15 min Insulin (Rat) (DA) RIA RIA-1253 250 Tests 18-24 h Insulin (Rat) Sensitive (DA) RIA RIA-1819 250 Tests 24/24h/20 min Insulin (Rat) ELISA EIA-2048 96 Wells 120/15 min Insulin (Rat) Ultrasensitive ELISA EIA-2943 96 Wells 120/30 min Insulin (Rat) High Range ELISA EIA-3985 96 Wells 120/15 min Insulin (Rat/Mouse) ELISA EIA-4127 96 Wells 120/30/15 min Insulin (Ovine) ELISA EIA-4739 96 Wells 120/15 min Insulin (Feline) ELISA EIA-4919 96 Wells 120/30 min Leptin (Human, Sandwich) ELISA EIA-2395 96 Wells 120/30/30/15 min Leptin (Human) ELISA EIA-4304 96 Wells 120/30/30 min Leptin (Human) (DA) RIA RIA-1624 250 Tests 24h/20 min Leptin (Human) (DA) RIA RIA-2997 125 Tests 24h/20 min Leptin (Human) Sensitive (DA) RIA RIA-1820 250 Tests 24/24h/20 min Leptin (Multispecies) RIA RIA-1874 250 Tests 24/24h/20 min Leptin (Mouse) ELISA EIA-3114 96 Wells 60/30/30 min

Immunoassays 19 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 20

Diabetes/Gastrointestinal und Pankreas

Product / Method Cat No. No. of Tests Incubation time

Leptin (Rat) ELISA EIA-4607 96 Wells 120/60/30/15 min Leptin (Mouse) (DA) RIA RIA-1625 250 Tests 24/24h/20 min Leptin (Mouse, Rat) ELISA EIA-4564 96 Wells 120/60/30 min Leptin (Murine) ELISA EIA-4551 96 Wells 60/60/30/10 min Leptin (Primate) (DA) RIA RIA-2077 250 Tests 22-24h/20 min Leptin Soluble Receptor ELISA EIA-4176 96 Wells 3h/10 min Lipase ELISA EIA-4459 96 Wells 30/15 min Microalbumin ELISA EIA-3881 96 Wells 30/15 min Orexin A (Human, Mouse, Rat) (DA) RIA* RIA-2391 125 Tests 16-24/16-24h/90 min Orexin B (Human) (DA) RIA* RIA-3149 125 Tests 16-24/16-24h/90 min P2 ANP (C-Type 2 Collagen) EIA-4446 96 Wells 120/30/20 min P-III-P (Procollagen III Peptide) (CT) RIA RIA-3750 100 Tests 5 h Pankreastatin (DA) RIA* RIA-0671 125 Tests 16-24/16-24h/90 min Pankreastatin (Rat) (DA) RIA* RIA-0689 125 Tests 16-24/16-24h/90 min Pancreatic Peptide ELISA EIA-4639 96 Wells 2 h/1 h/ 1 h Pancreatic Polypeptide direct (Hum.) (DA) RIA* RIA-3027 100 Tests 20-24/20-24h/30-60 min Pankrin ELISA EIA-3781 96 Wells 60/30/30/10 min Pepsinogen 1 (Human) ELISA EIA-4604 96 Wells 60/20 min Pepsinogen 11 (Human) ELISA EIA-4603 96 Wells 120/120 min Peptide YY (Porc., Rat) (DA) RIA* RIA-0676 125 Tests 16-24/16-24h/90 min Peptide YY total (Human) RIA RIA-4257 125 Tests 24h/24h/20 min PHM-27 (PHI) (Human) RIA* RIA-0681 125 Tests 16-24/16-24h/90 min Proinsulin ELISA EIA-1560 96 Wells Overnight/60/30 min Proinsulin total ELISA EIA-4156 96 Wells 60/60/30 min Proinsulin (DA) RIA RIA-1626 250 Tests 48/24h/20 min Proinsulin (Rat, Mouse) ELISA EIA-4609 96 Wells 120/30 min PYY (Human) (3-36) Specific RIA RIA-4647 125 Tests 24 h/24 h/20 min PYY (Human) ELISA EIA-4480 96 Wells overnight/120/30 min PYY (Rat) ELISA EIA-4473 96 Wells overnight/120/30 min Resistin human ELISA EIA-4194 96 Wells 90/60/30 min Resistin (human) ELISA EIA-4572 96 Wells 60/60/60/10 min Resistin (43-65) human RIA RIA-4303 125 Tests 4h/24h/90/20 min Resistin (Mouse) ELISA EIA-4554 96 Wells 60/60/30/10 min Resistin (Rat) ELISA EIA-4550 96 Wells 60/60/30/10 min Secretin (Porcine) (DA) RIA* RIA-1988 125 Tests 16-24/16-24h/90 min Somatostatin (DA) RIA RIA-3017 100 Tests 18-24/18-24h/30-60 min Somatostatin-28 (DA) RIA* RIA-0695 125 Tests 16-24/16-24h/90 min

20 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 21

Diabetes/Gastrointestinal und Pankreas

Product / Method Cat No. No. of Tests Incubation time

Substance P (DA) RIA* RIA-0693 125 Tests 16-24/16-24h/90 min Substance P ELISA EIA-3120 96 Wells 2/1h Urocortin (DA) RIA* RIA-2145 125 Tests 16-24/16-24h/90 min Urodilatin (DA) RIA* RIA-4765 125 Tests 16-24/16-24h/90 min VIP (Vasoactive Intestinal Pept.) direct (DA) RIA RIA-3019 100 Tests 20/20h/30 min

Immunoassays 21 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 22

Drug Monitoring Topical/Aktuell: Buprenorphine ELISA Cotinin (Saliva) ELISA Morphine (Urin) ELISA Morphine (Serum/Blood) ELISA Opiate (Urin) ELISA Opiate (Serum/Blood) ELISA

Product / Method Cat No. No. of Tests Incubation time

Amphetamines Metabolites ELISA EIA-2900 96 Wells 20/20 min Buprenorphine ELISA EIA-1498 96 Wells 30 min Chromoglycate ELISA EIA-1500 96 Wells 30 min Cotinin (Urine) ELISA EIA-1377 96 Wells 30/30 min Cotinin (Blood/Serum) ELISA EIA-3242 96 Wells 30/30 min Cotinin (Saliva) ELISA EIA-3243 96 Wells 30/30 min Fentanil ELISA EIA-1504 96 Wells 30 min Glycopyrrolate ELISA EIA-1505 96 Wells 30 min Methamphetamine ELISA EIA-1510 96 Wells 30 min Methylphenidate ELISA EIA-1511 96 Wells 30 min Morphine (Blood/Serum) ELISA EIA-4923 96 Wells 30/15 min Morphine (Blood/Serum) ELISA EIA-4924 480 Wells 30/15 min Morphine (Urine) ELISA EIA-4925 96 Wells 30/30 min Morphine (Urine) ELISA EIA-4926 96 Wells 30/30 min Opiate (Morphine/Heroin/Codein) ELISA EIA-2902 96 Wells 20/20 min Opiates (Urine) ELISA EIA-4922 480 Wells 30/30 min Opiates (Blood/Serum) ELISA EIA-4927 96 Wells 30/30 min Opiates (Blood/Serum) ELISA EIA-4928 480 Wells 30/30 min Opiates (Urine) ELISA EIA-4929 96 Wells 30/30 min Tricyclics ELISA EIA-1518 96 Wells 30 min VMA ELISA EIA-1620 96 Wells 60/25 min

22 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 23

Endocrinology/Endokrinologie New/Neu: CYR 61 mation in the diagnosis of deficiencies of DRG has developed worldwide the Hepcidin 25 (Bioactive) the iron metabolism such as hemochro- first assay for measuring Hepcidin. NOV matoses and anaemia. CTGF ELISA DRG hat den weltweit ersten Lactate Salivary ELISA Assay zur Bestimmung von Hepcidin VDBP ELISA Hepcidin entwickelt. Hepcidin ist ein kleines cysteinreiches t-PA ELISA Peptid, das in der Leber produziert Renin (active ) ELISA wird. Es reguliert ähnlich der Wir- Hepcidin kungsweise von Insulin und Zucker, Hepcidin is a small cystein-rich peptide die Aufnahme von Eisen. produced in the liver. This molecule regu- Die Bestimmung von Prohepcidin oder lates the absorption of iron in the body Hepcidin könnte bei Störungen des similarly to the correlation of insulin and Eisenmetabolismus in Zukunft eine sugar. The determination of Prohepcidin große Rolle zukommen, etwa bei or Hepcidin may provide valuable infor- Hämochromatosen oder Anämien.

Product / Method Cat No. No. of Tests Incubation time

Adipocyte FABP (AFABP, FABP4) Human ELISA EIA-4908 96 Wells 60/60/30/10 min Adrenalin ELISA EIA-1908 96 Wells 14-20h/120/40 min Adrenalin ELISA EIA-4306 96 Wells 3.5h Adrenalin / Epinephrine (DA) RIA RIA-0242 50 Tests 1/18h Adrenalin RIA RIA-4307 50 Tests 3h Adrenalin Research ELISA EIA-4776 96 Wells 30/120/30 min Alpha-1 Microglobulin ELISA EIA-5100 96 Wells 60/30/3x60/15 min Cat Combi (Adrenalin/Noradrenalin) ELISA EIA-3175 2 x 96 Wells 120/90/15 min Cat Combi (Adrenalin/Noradrenalin) ELISA EIA-4309 2 x 96 Wells 3.5h Cat Combi (Adrenalin/Noradrenalin) (DA) RIA RIA-4310 2 x 50 Tests 3h Cat Combi (Adrenalin/Noradrenalin) (DA) RIA RIA-1303 2 x 50 Tests 15-20h/15 min Cat Combi (Adrenalin/Noradrenalin) Saliva RIA RIA-4308 2 x 50 Tests on request CETP ELISA EIA-4621 96 Wells 60/60/10 min TriCat (Adren/Noradren/Dopamin) (DA) RIA RIA-2745 3 x 50 Tests 30/30/30 min TriCat Research ELISA EIA-4891 3 x 96 Wells 2h/15-20h/20-30 min Amyloid Beta 1-40 (Colorimetrisch) COL-3994 96 Tests 6,5 h Amyloid Beta 1-42 (Colorimetisch) COL-3995 96 Tests 6,5 h ANF (Rat) (DA) RIA* RIA-0723 125 Tests 16-24/16-24h/90 min

Met combi Plasma ELISA EIA-4865 2 x 96 Wells 16-20h 2-8°C, 90/15-30 min RT Prepro-ANF 26-55 (Human) (DA) RIA* RIA-1644 125 Tests 16-24/16-24h/90 min Prepro-ANF 56-92 (DA) RIA* RIA-1645 125 Tests 16-24/16-24h/90 min Prepro-ANF 104-116 (DA) RIA* RIA-1646 125 Tests 16-24/16-24h/90 min Prepro-ANF 104-123 (Human) (DA) RIA* RIA-0743 125 Tests 16-24/16-24h/90 min Angiotensin I (Human) (CT) RIA/ Plasma Renin RIA-0180 100 Tests 3 h Angiotensin II (Human) (DA) RIA RIA-3020 100 Tests 6/18-22 h/30-60 min ANP (DA) RIA RIA-3453 100 Tests 18h/overnight/30 min Alpha-ANP 1-28 (hum, can.) (DA) RIA* RIA-0715 125 Tests 16-24/16-24h/90 min ß ANP (Human) (DA) RIA* RIA-1643 125 Tests 16-24/16-24h/90 min

Immunoassays 23 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 24

Endocrinology

Product / Method Cat No. No. of Tests Incubation time

BNP-32 (Rat) (DA) RIA* RIA-0720 125 Tests 16-24/16-24h/90 min BNP-45 (Rat) (DA) RIA* RIA-0719 125 Tests 16-24/16-24h/90 min Prepro BNP 22-46 (Human) (DA) RIA* RIA-1653 125 Tests 16-24/16-24h/90 min Carbonylprotein ELISA EIA-5141 96 Wells 3 h/20/20/20 min Cat Combi Research ELISA EIA-4892 2 x 96 Wells 2h/15-20h/20-30 min Cat Combi (Plasma) ultra sensitive ELISA EIA-5131 2x96 Wells 2h/15-20 h/30/20/20-30m. C-Type Natr. Pept. 22 (Human, Rat) (DA) RIA* RIA-1118 125 Tests 16-24/16-24h/90 min CK-MB ELISA EIA-4361 96 Wells 120/15 min CRP (C-reactive Protein) ELISA EIA-1952 96 Wells 30/30/10 min CRP (C-reactive Protein) High sensitive ELISA EIA-3954 96 Wells 45/20 min CRP (Rat) ELISA EIA-4695 96 Wells 30/30/10 min CRP (Mouse) ELISA EIA-4823 96 Wells 60/30/5-10 min CRP ELISA HS (high sensitive) EIA-4584 96 Wells 30/30/10 min New CTGF ELISA EIA-5195 96 Wells 120/60/30/15 min CYR 61 EIA-5108 96 Wells 120/30/15 min Cystatin C (human) ELISA EIA-4394 96 Wells 30/30/10 min Dopamine (DA) RIA RIA-1983 50 Tests 1/18 h Dopamine (DA) RIA RIA-4311 50 Tests 3 h Dopamine ELISA EIA-4161 96 Wells 30/120/30/30-45 min Dopamine ELISA EIA-4615 96 Wells 120/60/40 min Dopamine Research ELISA EIA-4824 96 Wells 30/120/30/30 min Endothelin ELISA EIA-2374 96 Wells 18/1 h Endothelin-1 ELISA EIA-3111 96 Wells 18-24h/30/30 min Endothelin-1 (Human, Porcine) (DA) RIA* RIA-0660 125 Tests 16-24/16-24h/90 min Endothelin-2 (Human) (DA) RIA* RIA-0661 125 Tests 16-24/16-24h/90 min Endothelin-3 (Human, Rat) (DA) RIA* RIA-0662 125 Tests 16-24/16-24h/90 min Endothelin RIA RIA-4879 100 Tests 18-24/18-24h/30-60 min Big Endothelin-1 ELISA EIA-3110 96 Wells 18-24h/30/30 min Big Endothelin (Rat) ELISA EIA-3617 96 Wells overnight/30/30 min Big Endothelin-I (Human) (DA) RIA* RIA-0663 125 Tests 16-24/16-24h/90 min Big Endothelin-I (22-38) (Hum.) (DA) RIA* RIA-1127 125 Tests 16-24/16-24h/90 min Prepro-Endothelin (18-50) (DA) RIA* RIA-2399 125 Tests 16-24/16-24h/90 min Prepro-Endothelin (94-109) (Porcine) (DA) RIA* RIA-1129 125 Tests 16-24/16-24h/90 min FGF-19 ELISA (Human) ELISA EIA-5156 96 Wells 120/60/30/10 min Galactose neonate (incl. Membrane Plate) ELISA EIA-1486 192 Wells 60/60/30 min Galactose neonate (excl. Membrane Plate) ELISA EIA-1487 192 Wells 60/60/30 min GSTA (Glutathione S-Transferase Alpha) ELISA EIA-4930 96 Wells 60/60/30 min hGH (DA) RIA RIA-0225 100 Tests 120 min hGH IRMA RIA-3650 96 Tests 2 h hGH ELISA EIA-3552 96 Wells 1h/15 min Hepcidin Prohormone ELISA EIA-4644 96 Wells 60/30/15 min

24 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 25

Endokrinologie

Product / Method Cat No. No. of Tests Incubation time

Hepcidin ELISA EIA-4705 96 Wells 1/3 h/30/20 min New Hepcidin 25 (bioactive) ELISA EIA-5258 96 Wells 60/30/15 min 5-HIAA (Urine) ELISA EIA-4482 96 Wells 60/60/30 min Homocysteine ELISA (without controls) NOT FOR ITALY! EIA-2925 96 Wells 30/20/10 min Homocysteine Kit Controls for EIA-2925 EIA-2925C 3 vials HVA ELISA EIA-1573 96 Wells 60/25 min Histamine ELISA EIA-4005 96 Wells 15-20/1h/20-30 min Histamine Food ELISA EIA-4428 48 Wells 30/10/15 min Histamine Cell Cuture ELISA EIA-4616 96 Wells 15/30/10/15 min Histamine Rat RIA RIA-4312 50 Tests on request ICAM -1 ELISA EIA-4781 96 Wells 2h/10 min Lactate Salivary ELISA SLV-4764 96 Wells 30/10 min LDL (oxidized low density Lipoproteins) ELISA EIA-3430 96 Wells 2/1h/15 min LDL ox ELISA comp. EIA-4261 96 Wells 120/60/15 min Lp (a) ELISA EIA-4367 96 Wells 120/30 min Melatonin (direct) Saliva ELISA SLV-4779 96 Wells 16-20/2/1h/15 min Melatonin ELISA EIA-1431 96 Wells 14-20h/120/60 min Melatonin (Rat) RIA RIA-4483 100 Tests 1/1/20-24h/20 min Melatonin-Sulfate ELISA EIA-1432 96 Wells 120/30 min Melatonin (DA) Serum Plasma, Saliva RIA-3972 100 Tests 1h/1h/20-24h/20 min Melatonin Research RIA RIA-4496 100 Tests 1/1/20-24h/20/15 min Metanephrine Plasma ELISA EIA-4313 96 Wells Overnight Metanephrine Plasma RIA RIA-4314 50 Tests Overnight Metanephrine Urine RIA RIA-4316 50 Tests 1.5h Metanephrine Urine ELISA EIA-4315 96 Wells 2h MetCombi Plasma (Metanephrine/Normetan.) (DA) (RIA) RIA-4012 2 x 50 Tests 15 min/15-20h/15 min MetCombi Plasma RIA RIA-4466 2 x 50 Tests overnight/15 min MetCombi Plasma (Metanephrine/Normetan) ELISA EIA-4082 2 x 96 Wells 16-20h/30/20-30 min

MetCombi Plasma ELISA EIA-4865 2 x 96 Wells 16-20h 2-8°C, 90/15-30 min RT MetCombi Urine (Metanephrine/Normetan.) (DA) RIA RIA-4006 2 x 50 Tests 60/15 min MetCombi Urine (Metanephrine/Normetan.) ELISA EIA-4083 2 x 96 Wells 30/30/15-20 min MPO (Myeloperoxidase) ELISA EIA-4571 96 Wells 60/60/15 min Myelin Basic Protein (MBP) ELISA EIA-3725 96 Wells 2/1h/10 min Myoglobin ELISA EIA-3955 96 Wells 45/20 min Noradrenalin ELISA EIA-2049 96 Wells 14-20h/120/20 min Noradrenalin ELISA EIA-4317 96 Wells 3.5h Noradrenalin (DA) RIA RIA-4318 50 Tests 3h Noradrenalin Research ELISA EIA-4706 96 Wells 30/120/30 min Normetanephrine Plasma ELISA EIA-4319 96 Wells Overnight

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Endocrinology

Product / Method Cat No. No. of Tests Incubation time

Normetanephrine Urine ELISA EIA-4321 96 Wells 2h Normetanephrine Urine RIA RIA-4322 50 Tests 1.5h Normetanephrine Plasma RIA RIA-4320 50 Tests Overnight New NOV EIA-4836 96 Wells on request Oxytocin ELISA EIA-3117 96 Wells 18-24/1 h Oxytocin (DA) RIA RIA-0701 125 Tests 16-24/16-24h/90 min PAPP-A (ultrasensitive) ELISA EIA-4512 96 Wells 60/60/30/15 min Phenylalanin Neonate (incl. Membrane Plate) ELISA EIA-1477 192 Wells 60/45 min Phenylalanine Neonate (excl. Membrane Plate) ELISA EIA-1478 192 Wells 60/45 min Phenylalanine (PKU) neonatal Screening Assay ENZ-4743 2400 Wells 30/30 min PKU ENZ-4502 480 Tests 30/30 min PKU ENZ-4530 480 Tests 30/30 min PKU ENZ-4531 2400 Tests 30/30 min Relaxin ELISA EIA-4770 96 Wells 2/2h/20-30 min Renin active ELISA EIA-5125 96 Wells 120/30/15 min Renin IRMA RIA-4541 100 Tests 3h Renin Plasma Activity (PRA) RIA/ Angiotensin I RIA-0180 100 Tests 3h Retinol binding Protein (RBP) ELISA EIA-4391 96 Wells 60/60/20 min RLMB (Mouse) RIA RIA-4389 125 Tests 1h/1h/20 min Serotonin (DA) RIA RIA-3974 100 Tests 30/90/15/15 min Serotonin FAST ELISA EIA-5061 96 Wells 30/15/15 min

Serotonin Research (ultra sensitive) ELISA EIA-4642 96 Wells 30min/15-20h 2-8°C/30/20-30 min Serotonin Research (ultra sensitive) RIA RIA-4704 96 Wells 30min/15-20h/15 min TAU total ELISA EIA-3723 96 Wells 2/1h/30/60 min TAU total ELISA EIA-3724 192 Wells 2/1h/30/60 min t-PA (Human) ELISA EIA-5112 96 Wells 120/15 min TriCat Research ELISA EIA-4891 3x96 Wells 2h/15-20h/30 min TriCat (Adrenalin/Noradrenalin/Dopamin) ELISA EIA-4080 3x96 Wells 30/120/15 min TriCat (Adrenalin/Noradrenalin/Dopamin) ELISA EIA-4634 3x96 Wells 30/20/120/60/40 min TriCat (Adrenalin/Noradrenalin/Dopamin) Saliva RIA RIA-4323 3x50 Tests on request Extraction Set for EIA-4080 EIA-4081 48 Extractions Troponin I ELISA EIA-2952 96 Wells 90/20 min Trypsin Neonate ELISA EIA-1278 192 Wells 18-24h/60/15 min Vasopressin ELISA EIA-3122 96 Wells 18-24/1 h Vasopressin (DA) RIA (ADH, AVP) RIA-3021 100 Tests 24/24h/30 min [Arg8] Vasopressin (DA) RIA RIA-2318 50 Tests 24/24h/30 min VCAM-1 ELISA EIA-3675 192 Wells 3h/30/30 min Vitamin D binding Protein (VDBP) ELISA EIA-5088 96 Wells 60/60/10-20 min VMA ELISA EIA-1620 96 Wells 60/25 min Zeta Globin ELISA EIA-5048 96 Wells 30/30/15 min Zeta Globin ELISA EIA-5048 96 Wells 30/30/15 min

26 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 27

Fertility and Pregnancy/Fertilität PLGF New/Neu: (Placenta Growth Factor) AMH (Anti-Mullerian Hormone) ELISA PLGF is a new marker for Preeclamp- the soluble fms-like tyrosine kinase-1 Androstendione Saliva ELISA sia. is considered to have anti-angiogenic ER-60 (male infertility) ELISA Angiogenesis and vascular transforma- properties. Now a new PLGF-ELISA Estrone Saliva ELISA tion are important processes in the kit for routine diagnostics is available, Chemiluminescence Immunoassays: normal development of the placenta. which offers new possibilities in the 17 OH-Progesterone Abnormal angiogenesis and vascular prediction of preeclampsia. 3 alpha Diol G transformation are considered to DHEA-S be one of the main reasons for pre- The PLGF ELISA allows the early detec- Estradiol eclamptic pregnancies and intrauterine tion (15th week of pregnancy) of Estrone growth factor (PLGF), a member of the developmental risk factors of pre- Free Testosterone the VEGF family, is produced chiefly by eclampsia and is therefore an important Progesterone the placenta and is a potent angiogenic new tool in the health protection of Prolactin factor. The corresponding receptor, mother and child.

Product / Method Cat No. No. of Tests Incubation time

AFP ELISA EIA-1468 96 Wells 30/10 min AMH anti Mullerian Hormone EIA-4643 96 Wells 60/60/30/20-30 min 3 a Diol G CLA CLA-4649 96 Wells 15/15 min 3 alpha DIOL G (Androstandiol Glucuronide) ELISA EIA-4192 96 Wells 30/15 min 3 alpha DIOL G RIA RIA-4387 96 Tests 120 min Androstandiol Glucuronide (DA) RIA RIA-1541 100 Tests 3 h / 15 min Androstandiol Glucuronide (CT) RIA RIA-3376 100 Tests 3 h Androstenedione (DA) RIA RIA-1540 100 Tests 30/15 min Androstenedione (CT) RIA RIA-1539 100 Tests 30 min Androstenedione ELISA EIA-3265 96 Wells 60/15 min Androstenedione ELISA EIA-5050 96 Wells 60/15 min Androstenedione RIA (extraction) RIA-4180 100 Tests 60 min Androstenedione RIA (direct) RIA-4186 100 Tests 30-40 min Androstenedione Saliva ELISA SLV-4347 96 Wells 60/15 min Androstenedione Saliva ELISA SLV-4780 96 Wells 60/15 min Androstenedione RIA RIA-4388 96 Tests 60 min DHEA ELISA EIA-3415 96 Wells 60/15 min DHEA Salivary ELISA SLV-3012 96 Wells 60/20 min DHEA (DA) RIA RIA-1776 100 Tests 60/15 min DHEA (CT) RIA RIA-4053 100 Tests 2h DHEA-Sulfate (DA) RIA RIA-1536 100 Tests 30 min DHEA-Sulfate (CT) RIA RIA-4181 100 Tests 30 min DHEA Sulfate ELISA EIA-1562 96 Wells 60/15 min DHEA-S (Serum) CLA CLA-4667 96 Wells New ER 60 ELISA EIA-5263 96 Wells 45/45/30 min Estradiol ELISA EIA-2693 96 Wells 120/15 min Estradiol (US) ELISA (ultrasensitive) EIA-4399 96 Wells 4h/30 min Estradiol RIA RIA-4381 96 Tests 3h Estradiol (DA) RIA RIA-0220 100 Tests 90 min

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Fertility and Pregnancy

Product / Method Cat No. No. of Tests Incubation time

Estradiol (CT) RIA RIA-0192 100 Tests 90 min Estradiol (CT) RIA RIA-4182 100 Tests 3h Estradiol Salivary (ultrasensitive) SLV-4188 96 Wells 120/15 min Estradiol (Serum) CLA CLA-4664 96 Wells Estriol (Saliva) CLA CLA-4653 96 Wells 45/20/10-15 min Total Estriol ELISA EIA-3717 96 Wells 60/15 min Free Estriol ELISA EIA-1612 96 Wells 60/30 min Free Estriol Salivary ELISA SLV-3653 96 Wells 60/15 min Free Estriol (DA) RIA RIA-1535 100 Tests 30 min Estrogen Total (E1+E2) (DA) RIA RIA-1387 100 Tests 90/60 min Estrone ELISA EIA-4174 96 Wells 60/30 min Estrone (DA) RIA RIA-1543 100 Tests 60/15 min Estrone RIA RIA-4380 100 Tests 120 min New Estrone (Saliva) ELISA SLV-5228 96 Wells on request Estrone (Saliva) CLA CLA-4655 96 Wells 60/30/10-15 min Estrone (Serum) CLA CLA-4654 96 Wells 30/10-15 min Estrone Sulphate (DA) RIA RIA-2957 100 Tests 3h/15 min FSH ELISA EIA-1288 96 Wells 30/10 min FSH IRMA RIA-4378 96 Tests 60 min FSH IRMA (cubic size) RIA-4379 384 Tests 60 min Glycodelin (PP14) ELISA EIA-3779 96 Wells 90/30/15 min HCG ELISA EIA-1469 96 Wells 30/10 min HCG/ßHCG ELISA EIA-1911 96 Wells 60/15 min HCG+beta IRMA RIA-4495 96 Tests 30 min Free ßHCG ELISA EIA-4718 96 Wells 30/30/20 min Free ßHCG IRMA RIA-4492 100 Tests 60/30 min HPL ELISA EIA-1283 96 Wells 30/10 min HPL RIA RIA-4377 96 Tests 60 min 17a Hydroxy-Progesterone (Serum) CLA CLA-4665 96 Wells 17alpha-Hydroxyprogesterone (DA) RIA RIA-0235 100 Tests 60/20 min 17alpha-Hydroxyprogesterone (CT) RIA RIA-1273 100 Tests 150 min 17alpha-Hydroxyprogesterone ELISA EIA-1292 96 Wells 5/60/30 min 17alpha-OH-Progesterone (Salivary) ELISA SLV-3140 96 Wells 60/15 min 17alpha-OH-Prog. Neonate ELISA EIA-1429 192 Wells 18 h/30 min 17 OH Progesterone RIA RIA-4372 96 Tests 3h IGF BP1 (PP12) ELISA EIA-3780 96 Wells 60/15 min Inhibin alpha 1-32 (Human) (DA)* RIA-0686 125 Tests 16-24/16-24h/90 min LH Serum ELISA EIA-1289 96 Wells 30/10 min LH Urine ELISA EIA-1290 96 Wells 30/10 min

28 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 29

Fertilität und Schwangerschaft

Product / Method Cat No. No. of Tests Incubation time

LH IRMA RIA-4373 96 Tests 60 min LH IRMA (cubic size) RIA-4374 384 Tests 60 min Anti-Ovarian Ab (semi-quantitative) ELISA EIA-2937 96 Wells 60/60/30 min Anti-Ovarian Ab Ig-Typing (qualitative) ELISA EIA-3777 96 Wells 60/60/30 min Ovary Ab Latex Agglutination Test RAP-4938 50 Tests 2 min Ovary Ab Haemagglutination Test RAP-4939 40 Tests 90 min PAPP-A (Pregnancy Assoc. Plasma Protein A) ELISA EIA-2397 96 Wells 30/30/15 min PAPP-A (ultrasensitive) ELISA EIA-4512 96 Wells 60/60/30/15 min PLGF ELISA EIA-4529 96 Wells 60/60/30/30 min Pregnenolone ELISA EIA-4170 96 Wells 60/15 min Pregnenolone Serum ELISA EIA-4912 96 Wells 60/30/15 min Progesterone (DA) RIA RIA-0232 100 Tests 60 min Progesterone (CT) RIA RIA-0197 100 Tests 120 min Progesterone (DA) RIA RIA-1537 100 Tests 60/10/15 min Progesterone (CT) RIA RIA-2122 100 Tests 60 min Progesterone (CT) RIA RIA-4183 100 Tests 60 min Progesterone RIA RIA-4494 96 Tests 3h Progesterone (Salivary) ELISA SLV-2931 96 Wells 60/15 min Progesterone (Serum) CLA CLA-4663 96 Wells Progesterone ELISA EIA-1561 96 Wells 5/60/15 min Prolactin CLA CLA-4729 96 Wells Prolactin (CT) RIA RIA-0199 100 Tests 120 min Prolactin ELISA EIA-1291 96 Wells 30/10 min Prolactin IRMA RIA-4370 96 Tests 2h Prolactin IRMA (cubic size) RIA-4371 384 Tests 2h Saliva Control SLV-4576 3 x 2 ml Sperm Ab Latex Agglutinations Test RAP-4608 50 Tests 2 min Sperm Ab Ig-Typing ELISA EIA-4878 96 Wells 60/60/30 min Sperm Antibody ELISA (Serum) EIA-1826 96 Wells 60/60/30 min Sperm Antibody ELISA (Seminal Plasma) EIA-4249 96 Wells 60/60/30 min Sperm Ab Haemagglutination Test RAP-4940 40 Tests 90 min SHBG ELISA EIA-2996 96 Wells 30/15/12 min SHBG IRMA RIA-4184 100 Tests 120 min free Testosterone CLA CLA-4660 96 Wells 30/10-15 min free Testosterone EIA-4638 96 Wells 60/10-15 min Testosterone (DA) RIA RIA-0240 100 Tests 2/1h Testosterone (CT) RIA RIA-0200 100 Tests 120 min Testosterone RIA RIA-4386 96 Tests 3h Testosterone ELISA EIA-1559 96 Wells 60/15 min

Immunoassays 29 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 30

Fertility and Pregnancy

Product / Method Cat No. No. of Tests Incubation time

Testosterone (Salivary), ELISA SLV-3013 96 Wells 60/30 min Testosterone (Saliva) CLA CLA-4661 96 Wells 30/30/10-15 min Testosterone (Serum) CLA CLA-4662 96 Wells Testosterone, dihydro-, ELISA EIA-2330 96 Wells 60/15 min Testosterone, dihydro-, (DA) RIA RIA-2316 100 Tests 2h II-keto Testosterone ELISA EIA-4526 96 Wells 18h/60 min Free Testosterone ELISA EIA-2924 96 Wells 60/15 min Free Testosterone (CT) RIA RIA-0614 100 Tests 60 min Free Testosterone RIA RIA-4369 100 Tests 2.5h Testosterone RIA (extraction) RIA-4179 100 Tests 60 min Testosterone RIA (direct) RIA-4185 100 Tests 3h Zona Pellucida Ab Ig-Typing ELISA EIA-3778 96 Wells 60/60/30 min

30 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 31

Pituitary/Adrenal Function

New/Neu: • Total Assay Time: 3 hours • Sample Volume: 75 µl of EDTA Plasma Renin active ELISA • Crossreactivity with Prorenin: 0.69% Assay characteristics: • Mean Intra Assay Precision: 6.4 • Assay Principle: Sandwich ELISA • Mean Inter Assay Precision: 6.7 • Dynamic Range: 1.13-128 pg/mL of active Renin • Analytical Sensitivity: 1.13 pg/mL Product / Method

ACTH ELISA EIA-3647 96 Wells 4h/30 min ACTH (DA) RIA RIA-0205 50 Tests 16 h ACTH IRMA RIA-1627 100 Tests 18-22 h ACTH IRMA RIA-4735 96 Tests 120/60 min ACTH I-24 (Human) ( DA) RIA* RIA-0710 125 Tests 16-24/16-24h/90 min ACTH 18-39 (Human) (DA) RIA* RIA-1107 125 Tests 16-24/16-24h/90 min ACTH (Rat) (DA) RIA* RIA-1109 125 Tests 16-24/16-24h/90 min New Aldosterone EIA-5298 96 Wells 90/20 min Aldosterone ELISA EIA-4128 96 Wells 60/20 min Aldosterone ELISA EIA-4600 96 Wells 60/10-15 min Aldosterone CLA CLA-4650 96 Wells 60/10 min Aldosterone direct (CT) RIA RIA-2317 100 Tests 3 h Calcitonin Gene Rel. Pept. (CGRP) (Human) (DA) RIA* RIA-0656 125 Tests 16-24/16-24h/90 min CGRP (Rat) (DA) RIA* RIA-0655 125 Tests 16-24/16-24h/90 min Calcitonin Gene Related Peptide II (DA) RIA* RIA-0657 125 Tests 16-24/16-24h/90 min CBG ( Transcortin) (CT) RIA RIA-3671 100 Tests 20/20 min Corticotropin Releasing Factor (Human, Rat) (DA) RIA* RIA-0702 125 Tests 16-24/16-24h/90 min Corticosterone ELISA EIA-4164 96 Wells 60/15 min Corticosterone (Rat, Mouse) (DA) RIA RIA-0210 100 Tests 120 min Corticosterone (Rat, Mouse) (DA) RIA RIA-1364 200 Tests 120 min Cortisol ELISA EIA-1887 96 Wells 60/15 min Cortisol (Saliva) HS (high sensitive) ELISA SLV-4635 96 Wells 60/30 min Cortisol (Salivary) ELISA SLV-2930 96 Wells 60/30 min Cortisol (Serum) CLA CLA-4666 96 Wells 30/10 min Cortisol (Urinary) ELISA EIA-2989 96 Wells 60/15 min Cortisol (DA) RIA RIA-1635 100 Tests 45 min Cortisol (CT) RIA RIA-0189 100 Tests 45 min 11-Desoxycortisol (DA) RIA RIA-4777 100 Tests 2.5h Gastrin (Human) ELISA EIA-4187 96 Wells 2/3h Gastrin I (I-17) Rat ELISA EIA-4501 96 Wells 2/3h Gastrin Releasing Peptide (Human) (DA) RIA* RIA-1137 125 Tests 16-24/16-24h/90 min Growth Hormone RF (Human) (DA) RIA* RIA-0697 125 Tests 16-24/16-24h/90 min Growth Hormone RF (Rat) (DA) RIA* RIA-0699 125 Tests 16-24/16-24h/90 min LH Releasing Hormone (DA) RIA* RIA-0683 125 Tests 16-24/16-24h/90 min Renin active ELISA EIA-5125 96 Wells Transcortin (CBG) (DA) RIA RIA-3671 100 Tests 20/20 min Urotensin II (Human) (DA) RIA* RIA-3448 125 Tests 16-24/16-24h/90 min Urotensin II (Rat) (DA) RIA* RIA-3550 125 Tests 16-24/16-24h/90 min

Immunoassays 31 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 32

Immunology/Hematology

New/Neu: PAP (Plasmin alpha2-antiplasmin complex) current activity of the fibrinolytic system. Elevated The removal of polymerized fibrin from the vas- PAP concentrations have been reported in pati- • Annexin V Antibody ELISA cular system by proteolytic degradation (fibrino- ents with DIC. An increase in PAP concentrations • IP-10 (human) ELISA lysis) is important for maintaining the haemost- has also been observed during fibrinolytic thera- • SHLA-G ELISA atic balance. The key enzyme of the fibrinolytic pies. • Procalcitonin (human) ELISA system is plasmin. Besides its fibrinolytic function DRG PAP ELISA is an enzyme immunoassay for • Interleukin 21 ELISA in the plasma, plasmin also plays a central role the quantitative determination of plasmin/ in the activation of degenerative (e. g. collagen- alpha2-antiplasmin complex in human plasma, ases) and inflammatory (e. g. complement and is intended for use in the diagnosis of hypo- system) processes in the tissue. and hyperfibrinolytic states.

Defects or deficiencies in a component of the C5a fibrinolytic system can lead to thromboembolic A proteolytic product of the complement protein diseases. Conversely, hyperfibrinolytic states C5. C5a is an important proinflammatory increase the risk of haemorrhage through acce- mediator with both anaphylatoxic and che- lerated degradation of fibrinogen. Plasmin is motactic effects. Therefore, it is active in engen- effectively bound in plasma by its inhibitor dering both the vascular und cellular phases of alpha2-antiplasmin, forming the plasmin/ the inflammatory response. alpha2-antiplasmin complex (PAP). The plasma These products were formerly manufac- PAP concentration is thus a measure of the tured by Dade Behring, now exclusive by DRG Instruments.

PAP durch seinen Inhibitor alpha-2-Antiplasmin C5a (Plasmin alpha2-antiplasmin Komplex) unter Bildung des Plasmin-Komplexes (PAP) C5a ist ein an anaphylaktischen Reaktionen Die Entfernung polymarisierten Fibriris aus gebunden. Die Konzentration von PAP im beteiligter Teilkomplex des Komplementsy- dem Gefäßsystem durch proteolytischen Plasma ist somit ein Maß für die aktuelle Akti- stems. Anaphylatoxine wie C5a bewirken Abbau (=Fibrinolyse) ist für die Erhaltung vität des fibrinolytischen Systems. Erhöhte Spasmen der glatten Muskulatur (Bronchi- des hämostatischen Gleichgewichts wichtig. Konzentrationen von PAP werden bei Patien- alspasmen) und die Steigerung der Per- Das Schlüsselenzym des bibrinolytischen ten mit DIC beobachtet. Ein Anstieg der PAP- meabilität der Blutkapillaren sowie der Systems ist Plasmin. Neben seiner fibrinoly- Konzentration wurde auch im Verlauf fibrino- Chemotaxis. Der DRG C5a ELISA wird zur tischen Funktion im Plasma spielt Plasmin logischer Therapien beobachtet. Auf Grund quantitativen Bestimmung von Anaphylato- eine zentrale Rolle bei der Aktivierung der multifunktionellen Aufgaben des Plasmins xin C5a in Plasma oder Urin eingesetzt. degradativer und entzündlicher Prozesse im ist PAP auch bei Patienten mit rheumatischen Die beiden vorgenannten Produkte Gewebe. Erkrankungen erhöht. wurden von Dade Behring ent- Defekte oder Mangelzustände einer Kom- wickelt. Die Produktion und der Ver- ponente des fibrinolytischen Systems kön- DRG PAP ELISA ist ein Enzymimmunoassay trieb der Tests erfolgt durch DRG nen zu thromboembolischen Erkrankungen zur quantitativen Bestimmung von Plasmin- Instruments GmbH. führen. Auf der anderen Seite erhöhen alpha2-Antiplasmin-Komplex in humanen hyperfibrinolytische Zustände durch den Plasma zur Diagnose von hypo- und hyperfi- verstärkten Abbau des Fibrinogens das Blu- brinolytischen Zuständen. tungsrisiko. Plasmin wird im Plasma effektiv

Product / Method Cat No. No. of Tests Incubation time

Aggrecan PG ELISA EIA-3678 96 Wells 120/15 min Akt (Total) (Human, Mouse, Rat) ELISA EIA-3996 96 Wells 120/60/30/30 min Akt [pS473] (Human, Mouse, Rat) ELISA EIA-3997 96 Wells 120/60/30/30 min New Annexin V Antibody EIA-5208 96 Wells 120/60/10 min ARAb RRA (Acetylchol. Rec.Ab) RIA-2956 100 Tests 30 min ARAb RRA (Acetylchol. Rec.Ab) RIA-4520 25 Tests 30 min Caspase-8 (human) ELISA EIA-4863 96 Wells 120/60/20 min Caspase-9 (human) ELISA EIA-4860 96 Wells 120/60/20 min CIq ELISA (Circ. Immune Complexes) ELISA EIA-2332 96 Wells 30/15/15 min CIq ELISA (Circ. Immune Complexes) ELISA EIA-3169 96 Wells 30/30/15 min Complement C3a des Arg ELISA EIA-3641 96 Wells 120/60 min Complement C4a des Arg ELISA EIA-3642 96 Wells 120/60 min C3bi ELISA EIA-3990 96 Wells 30/30/15 min C3d ELISA (Circ. Immune Complexes) EIA-2333 96 Wells 30/15/15 min C3d ELISA (Circ. Immune Complexes) EIA-3170 96 Wells 30/30/15 min

32 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 33

Immunologie/Hämatologie

Product / Method Cat No. No. of Tests Incubation time

C5a ELISA EIA-3327 192 Wells 20/15/15 min sCD14 ELISA EIA-1304 96 Wells 120/60/15 min sCD23 (human) ELISA EIA-4833 96 Wells 120/60/10 min sCD30 (human) ELISA EIA-4849 96 Wells 3h/10 min sCD40 (human) ELISA EIA-4850 96 Wells 120/60/10 min sCD40 Ligand (human) ELISA EIA-4851 96 Wells 2h shaking or overnight sCD40 Ligand (human) High Sensitive ELISA EIA-4852 96 Wells 120/60/10 min CH 50 ELISA EIA-3989 96 Wells 120/15 min Cyclosporin direct RIA RIA-5093 100 Tubes 120 min Cytochrome C (Human) ELISA EIA-4490 96 Wells 60/60/30/30 min DR 4 (Human) ELISA EIA-3998 96 Wells 120/60/30/30 min Endostatin ELISA EIA-4467 96 Wells 3h/30/20 min Erythropoietin ELISA EIA-3646 96 Wells 16-24h/45 min FAS (Apo-1/FAS/CD95) ELISA EIA-3875 96 Wells 60/30/30 min Fibronectin ELISA EIA-1736 96 Wells 60/60 min Galectin-3 (Human) ELISA EIA-4858 96 Wells 120/60/10 min GCSF (Human) ELISA EIA-3876 96 Wells 4 h GM-CSF (Human) ELISA EIA-4859 96 Wells 3 h/10 min GM-CSF (Human) Supersensitive ELISA EIA-3877 96 Wells 90/30/30 min GM-CSF (Mouse) ELISA EIA-3416 192 Wells 4 h GRO/CINC-1 (Cytokine ind. Neutrophile) (Rat) ELISA EIA-3618 96 Wells 60/30/30 min GRO/CINC-3 (Rat) ELISA EIA-3626 96 Wells 60/30/30 min HAMA ELISA EIA-4195 96 Wells 30/15 min Histamin ELISA EIA-4005 96 Wells upon request Histamin (DA) RIA RIA-3975 100 Tests 15/60/15/15 min HNP 1-3 (Human) ELISA EIA-5139 2 x 96 Wells 60/60/60/20-30 min Hsp 60, anti (Human) ELISA EIA-4602 96 Wells 60/60/30/15 min Hsp 70, anti- (Human) ELISA EIA-4470 96 Wells 120/60/15 min HVA ELISA EIA-1573 96 Wells 60/25 min IgA-CIC ELISA EIA-3988 96 Wells 120/60/30 min IgE ELISA EIA-1788 96 Wells 30/30/20 min IgG-CIC ELISA EIA-3986 96 Wells 120/60/30 min IgG (Mouse) ELISA EIA-5052 96 Wells 60/30/10 min IgM-CIC ELISA EIA-3987 96 Wells 120/60/30 min Interferon ß ELISA EIA-2088 96 Wells 16-20h/30 min IFN alpha (Human) ELISA EIA-4766 96 Wells 120/15 min INF-gamma (Human) ELISA EIA-4434 96 Wells 120/15 min INF-gamma (Mouse) ELISA EIA-4931 96 Wells 120/30/30 min INF-gamma (Mouse) ELISA EIA-4932 192 Wells 120/30/30 min

Immunoassays 33 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 34

Immunology/Hematology

Product / Method Cat No. No. of Tests Incubation time

INF-gamma (Mouse) ELISA EIA-3299 96 Wells 3h/ 30 min INF-gamma (Porcine) ELISA EIA-4828 96 Wells 60/60/30/10 min INF-gamma (Rat) ELISA EIA-4582 96 Wells 120/60/45/20 min INF-gamma (Rat) ELISA EIA-4583 192 Wells 120/60/45/20 min Interleukin-1 alpha (Human) ELISA EIA-4839 96 Wells 120/60/10 min Anti-Interleukin-1 alpha (Human) ELISA EIA-4853 96 Wells 120/60/45/20 min Interleukin-1ß (Human) ELISA EIA-4437 96 Wells 120/15 min Interleukin-1ß (Mouse) ELISA EIA-3379 192 wells 3h/30 min Interleukin-1ß (Porcine) ELISA EIA-3181 192 Wells 4 h Interleukin-1ß (Rat) ELISA EIA-4911 96 Wells 120/60/10 min Interleukin IRA ELISA EIA-4500 96 Wells 120/60/30 min Interleukin-2 (Human) ELISA EIA-4436 96 Wells 120/15 min Interleukin-2 (Mouse) ELISA EIA-3163 192 wells 3 h Interleukin-2 Receptor (Human) ELISA EIA-2087 96 Wells 3 h Interleukin-2 Receptor (Human) ELISA EIA-4835 96 Wells 3 h/10 min Interleukin-4 (Human) ELISA EIA-4435 96 Wells 120/30 min Interleukin-4 (Mouse) ELISA EIA-3384 192 Wells 3 h Interleukin-4 (Porcine) ELISA EIA-4091 192 Wells 120/30/30 min Interleukin-5 (Human) ELISA EIA-4832 96 Wells 120/60/10 min Interleukin-6 (Human) ELISA EIA-4640 96 Wells 60/60/15 min Interleukin-6 (Mouse) ELISA EIA-3386 192 Wells 3h/30 min Interleukin-6 (Rat) ELISA EIA-4845 192 Wells 120/60/10 min Interleukin-6 (Porcine) ELISA EIA-1869 96 Wells overnight/120/20/12-15 min Interleukin-6 Receptor ELISA EIA-4844 96 Wells 3 h/10 min Interleukin-6 IRMA RIA-2011 100 Tests 16-20/2 h Interleukin-8 (Human) ELISA EIA-4700 96 Wells 4 h 30 min Interleukin-8 (Porcine) ELISA EIA-3183 192 Wells 4 h Interleukin-10 (Human) ELISA EIA-4699 96 Wells 4 h 30 min Interleukin-10 (Porcine) ELISA EIA-3185 192 Wells 3 h Interleukin-10 (Mouse) ELISA EIA-3380 192 Wells 5h/20 min Interleukin-10 (Rat) ELISA EIA-4773 96 Wells 120/60/15 min Interleukin-12 + p40 (Human) ELISA EIA-4698 96 Wells 4 h 30 min Interleukin-12 p70 (Human) ELISA EIA-4843 96 Wells 120/60/10 min Interleukin-12 p70, (Rat) ELISA EIA-4001 96 Wells 120/60/30/30 min Interleukin-12 p70, (Mouse) ELISA EIA-4842 96 Wells 120/60/10 min Interleukin-12 (Mouse) ELISA EIA-4920 96 Wells 120/60/20 min Interleukin-13 (Human) ELISA EIA-4841 96 Wells 60/10 min Interleukin-13 (Rat) ELISA EIA-3391 192 Wells 3 h Interleukin-15 (Human) ELISA EIA-3392 96 Wells 2 h

34 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 35

Immunologie/Hämatologie

Product / Method Cat No. No. of Tests Incubation time

Interleukin-17 (Human) ELISA EIA-4840 96 Wells 120/60/10 min Interleukin-18 (Rat) ELISA EIA-4002 96 Wells 120/60/30/30 Interleukin-18 (Human) ELISA EIA-4061 96 Wells 60/60/30 min New Interleukin-21 (Human) EIA-5294 96 Wells 180/60/10 min Interleukin-23 (Human) ELISA EIA-5058 96 Wells 120/60/60/15 min Involucrin ELISA EIA-0144 96 Wells overnight/overnigt/30/60 min New IP-10 (Human) ELISA EIA-5244 96 Wells 180/30/30 min LL-37 (Human) ELISA EIA-5140 2 x 96 Wells 60/60/60/20-30 min LIF-HILDA (Leukemia Inhibitory Factor) ELISA EIA-3878 96 Wells 4h/30 min MCP-I (Human) ELISA EIA-4857 96 Wells 120/10 min MCP-1 (Mouse) ELISA EIA-5091 96 Wells 120/60/10 min MCP-1 (Mouse) ELISA (Monocyte Chemoattr.) EIA-4071 192 Wells 120/45/45/20 min MCP-1 (Rat) ELISA (Monocyte Chemoattr.) EIA-4072 192 Wells 90/30/30 min MCP-1 (Rat) ELISA (Monocyte Chemoattr. Protein) EIA-3620 96 Wells 60/30/30 min MIP-1ß (Human) ELISA (Macrophage Inflamm. Prot.) EIA-3788 96 Wells 4 h MIP-2 (Rat) ELISA EIA-3789 96 Wells 3h/30 min MIP-5 (Human) ELISA EIA-3790 96 Wells 3 h MMP-13 (Human) ELISA EIA-4862 96 Wells 120/60/20 min MMP-9 (Human) ELISA EIA-4861 96 Wells 60/10 min Myeloperoxidase (MPO) ELISA EIA-4165 96 Wells 60/60/30/30 min Neopterin ELISA EIA-1476 96 Wells 120/30 min Neopterin ELISA EIA-2949 96 Wells 120/120/30 min PAP micro ELISA (Plasmin a2-antiplasmin complex) EIA-3763 192 Wells 15/15/15 min PAP micro 2000 ELISA EIA-5084 192 Wells 30/30/15 min PMN Elastase (Human) ELISA EIA-4856 96 Wells 60/60/20 min New Procalcitonin (Human) ELISA EIA-5291 96 Wells 120/60/30/10 min Protein A ELISA EIA-1823 96 Wells 60/60/30/15 min sApo1/FAS (Human) ELISA EIA-4854 96 Wells 60/60/10 min sFAS Ligand (Human) ELISA EIA-4855 96 Wells 120/60/10 min sgp130/sCD130 (Human) ELISA EIA-4768 96 Wells 60/30/10-15 min sRankl (free) ELISA EIA-4771 96 Wells 2 h/1/1 h/10 min sRankl (total) ELISA EIA-4772 96 Wells 16 h/1/1 h/10 min sE-Selectin (human) ELISA EIA-4775 96 Wells 120/10 min New sHLA-G ELISA EIA-5290 96 Wells 16-20 h/60/25 min sL-Selectin (human) ELISA EIA-4363 96 Wells 120/15 min sL-Selectin (human) ELISA EIA-4875 96 Wells 120/15 min sP-Selectin (human) ELISA EIA-4874 96 Wells 120/15 min sP-Selectin (human) ELISA EIA-4365 96 Wells 120/15 min

Immunoassays 35 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 36

Immunology/Hematology

Product / Method Cat No. No. of Tests Incubation time

TAFI (Human) ELISA EIA-4606 96 Wells 10/60/60/10 min TGF beta1 ELISA EIA-1864 96 Wells 3/2h/45/45/15 min TGF beta 2 ELISA EIA-2396 96 Wells 3/2h/20/10 min TNF alpha (Human) ELISA EIA-4641 96 Wells 120/120/30 min TNF alpha (Human) RIA RIA-2081 96 Tests 16-20 h TNF alpha (Mouse) ELISA EIA-3167 192 Wells 120/30 min TNF alpha (Porcine) ELISA EIA-3187 192 Wells 4 h TNF alpha (Rat) ELISA EIA-4774 96 Wells 120/60/15 min TNF beta (Human) ELISA EIA-5128 96 Wells 4h/15 min TRAIL (Human) ELISA EIA-4009 96 Wells 120/60/30/30 min Transferrin Receptor (TfR) human ELISA EIA-4256 96 Wells 60/60/10 min sVCAM-1 (human) ELISA EIA-4873 96 Wells 120/15 min sVEGF-1/Receptor 1 (Human) ELISA EIA-4822 96 Wells 120/60/20 min VEGF-A (Human) EIA-4826 96 Wells 3 h/1 h/10 min VEGF-C (Human) EIA-4825 96 Wells 120/60/10 min VEGF-C (Rat) ELISA EIA-5101 96 Wells 120/60/10 min

36 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 37

Cardiovascular Diseases

New/Neu: Renin active ELISA Aldosterone ELISA Assay characteristics: CYR 61 ELISA • Assay Principle: Sandwich ELISA • Dynamic Range: 1.13-128 pg/mL of active Renin Papp-A ultrasensitive ELISA* • Total Assay Time: 3 hours highsensitive CRP ELISA • Sample Volume: 75 µl of EDTA Plasma LDL oxidized ELISA (comp.) • Crossreactivity with Prorenin: 0.69% Fetuin A ELISA • Mean Intra Assay Precision: 6.4 Aldosterone ELISA • Mean Inter Assay Precision: 6.7 • Analytical Sensitivity: 1.13 pg/mL *) not available in USA

Product / Method Cat No. No. of Tests Incubation time

Aldosterone CLA CLA-4586 96 Wells 60/10 min New Aldosterone ELISA EIA-5298 96 Wells 90/20 min Aldosterone ELISA EIA-4128 96 Wells 60/20 min Aldosterone direct (CT) RIA RIA-2317 100 Tests 3 h Aldosterone ELISA EIA-4680 96 Wells 60/10-15 min Apo a ELISA EIA-1907 96 Wells ANP (DA) RIA RIA-3453 100 Tests 18h/overnight/30 min Alpha-ANP 1-28 (hum, can.) (DA) RIA* RIA-0715 125 Tests 16-24/16-24h/90 min ß ANP (Human) (DA) RIA* RIA-1643 125 Tests 16-24/16-24h/90 min Brain Natr. Pept. (BNP 32) (Human) (DA) RIA* RIA-0721 125 Tests 16-24/16-24h/90 min BNP-32 (Rat) (DA) RIA* RIA-0720 125 Tests 16-24/16-24h/90 min BNP-45 (Rat) (DA) RIA* RIA-0719 125 Tests 16-24/16-24h/90 min Prepro BNP 22-46 (Human) (DA) RIA* RIA-1653 125 Tests 16-24/16-24h/90 min CK-MB ELISA EIA-4361 96 Wells 120/15 min CRP (C-reactive Protein) ELISA EIA-1952 96 Wells 30/30/10 min CRP (C-reactive Protein) High sensitive ELISA EIA-3954 96 Wells 45/20 min CRP hs ELISA EIA-4584 96 Wells 30/30/10 min CYR 61 ELISA EIA-5108 96 Wells 120/30/15 min Endothelin-1 (Human, Porcine) (DA) RIA* RIA-0660 125 Tests 16-24/16-24h/90 min Endothelin-2 (Human) (DA) RIA* RIA-0661 125 Tests 16-24/16-24h/90 min Endothelin-3 (Human, Rat) (DA) RIA* RIA-0662 125 Tests 16-24/16-24h/90 min Big Endothelin-1 (Human) (DA) RIA* RIA-0663 125 Tests 16-24/16-24h/90 min Big Endothelin-1 (22-38) (Hum.) (DA) RIA* RIA-1127 125 Tests 16-24/16-24h/90 min Fetuin A ELISA EIA-4522 96 Wells 120/30/20 min Homocysteine ELISA (without controls) NOT FOR ITALY! EIA-2925 96 Wells 30/20/10 min Homocysteine Kit Controls for EIA-2925 EIA-2925 C 3 vials LDL (ox sandwich) ELISA EIA-3430 96 Wells 2/1h/15 min LDL ox ELISA competitive EIA-4261 96 Wells 120/60/15 min Lp (a) ELISA EIA-4367 96 Wells 120/30 min

Immunoassays 37 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 38

Cardiovascular Diseases

Product / Method Cat No. No. of Tests Incubation time

Myoglobin ELISA EIA-3955 96 Wells 45/20 min PAPP-A (ultrasensitive) ELISA (not av. in US) EIA-4512 96 Wells 60/60/30/15 min Troponin 1 ELISA EIA-2952 96 Wells 90/20 min Renin IRMA RIA-4541 100 Tests 3 h Renin active ELISA EIA-5125 96 Wells 90/90/15 min 11-dehydro Thromboxan B2 ELISA EIA-4684 96 Wells 120/60 min

Rapid Screen Tests Product / Method Cat No. No. of Tests Incubation time

CRP Rapid Test RAP-4168 20 Tests 15 min (min. 1000 Tests) CRP (Serum) Cassette Test RAP-4444 25 Tests 10 min Myoglobin/CK-MB/Troponin 1 Combo Test RAP-4443 20 Tests 10 min Myoglobin Whole Blood RAP-3372 20 Tests Cassette Troponin 1/Myoglobin Cassette Test RAP-4442 20 Tests 15 min (min. 1000 Tests)

38 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 39

Bone/Mineral Metabolism New/Neu: 25 OH Vitamin D total ELISA

Product / Method Cat No. No. of Tests Incubation time

Calcitonin IRMA CT RIA-3643 96 tests 18 h Calcitonin (Rat) (DA) RIA* RIA-1121 125 Tests 16-24/16-24h/90 min Calcitonin ELISA EIA-3648 96 Wells 4h/30 min Calcitonin ELISA EIA-1552 96 Wells 18h/30 min cAMP direct ELISA EIA-3065 96 Wells 120/60 min cAMP ELISA EIA-3062 96 Wells 120/60 min cAMP RIA RIA-4750 100 Tests 20-24 h/15 min cGMP direct ELISA EIA-3069 96 Wells 120/60 min cGMP ELISA EIA-3067 96 Wells 120/60 min Deoxypyridinoline (DPD) RIA RIA-5129 100 Tests 120 min Ferritin ELISA EIA-1872 96 Wells 60/20 min Ferritin ELISA EIA-4408 96 Wells 60/10 min Fetuin A ELISA EIA-4522 96 Wells 120/30/20 min FGF-23 ELISA EIA-4737 96 Wells 3 h/30 min Hepcidin Prohormone ELISA EIA-4644 96 Wells 60/30/15 min OPG (Rat/Mouse) ELISA EIA-5155 96 Wells 120/120/20/20 min Osteocalcin intact (Human) ELISA EIA-3375 96 Wells 120/30 min Osteocalcin intact (Human) ELISA EIA-1735 96 Wells 2.5 h/30 min Osteocalcin intact (Human) RIA RIA-3651 96 Tests 120 min Osteocalcin (Human) (DA) RIA RIA-1542 100 Tests 24 h Osteocalcin (Mouse) ELISA EIA-4010 96 Wells 18-24h/30/15 min Osteocalcin (Rat) ELISA EIA-2095 96 Wells 18-24h/60/60/30 min Osteopontin (OPN) ELISA EIA-4716 96 Wells 60/30/30 min Osteopontin (Human) ELISA EIA-3116 96 Wells 60/30/30 min Osteopontin (Mouse) ELISA EIA-3557 96 Wells 60/30/30 min Osteopontin (Mouse) ELISA EIA-4933 96 Wells 60/30/30 min Osteopontin (Rat) ELISA EIA-3556 96 Wells 60/30/30 min Osteopontin (Rat) ELISA EIA-4934 96 Wells 60/30/30 min Osteoprotegerin (Human) ELISA EIA-4573 96 Wells 60/60/30/10 min Osteoprotegerin (OPG) ELISA EIA-3551 96 Wells 18-24h/60/15-20 min Osteoprotegerin (OPG) Mouse ELISA EIA-4734 96 Wells 3/1 h/30 min PTH Intact ELISA EIA-1554 96 Wells 120/30/30 min PTH intact ELISA EIA-3645 96 Wells 3h/30 min PTH Intact IRMA RIA-3649 96 tests 60/60 min

Immunoassays 39 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 40

Bone/Mineral Metabolism

Product / Method Cat No. No. of Tests Incubation time

PTH intact (Rat) ELISA EIA-4935 96 Wells 3h/30 min PTH 1-34 (Human) (DA) RIA* RIA-1152 125 Tests 16-24/16-24h/90 min PTH 1-38 (Human) (DA) RIA* RIA-1153 125 Tests 16-24/16-24h/90 min PTH 1-44 (Human) (DA) RIA* RIA-1651 125 Tests 16-24/16-24h/90 min PTH 1-34 (Rat) (DA) RIA* RIA-1155 125 Tests 16-24/16-24h/90 min Vit. B 12 Folic Acide J-125/Co57 (RIA (SP, no boil) RIA-1990 100 Tests 10/10/80 min 1.25 (OH) 2 Vitamin D ELISA EIA-4193 96 Wells 18h/1h/30 min 1.25 (OH) 2-Vitamin D RIA RIA-4782 48 Tests 15-20h/15 min 25 OH Vitamin D (direct) ELISA EIA-4696 96 Wells 60/overnight/60/25 min 25 OH Vitamin D (CT) RIA RIA-2993 96 Tests 2 h New 25 OH Vitamin D (total) ELISA EIA-5396 96 Wells 30/90/20 min New 25 OH Vitamin D total RIA RIA-5292 96 Wells 120 min

40 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 41

Leukotrienes/Prostaglandins New/Neu: Prostaglandin E2 HS ELISA COX-II (Human) ELISA Cardiovascular Diseases 11-dehydro-Thromboxan B2 ELISA

Product / Method Cat No. No. of Tests Incubation time

COX-II (Human) ELISA EIA-5158 96 Wells 60/30/30 min New Direct 8-iso-PGF2a ELISA EIA-5295 96 Wells 120/45 min 12-HETE ELISA EIA-1584 96 Wells 2/3h 15-HETE ELISA EIA-1411 96 Wells 18-24h/1h Leukotriene B4 ELISA EIA-3088 96 Wells 1/2h Cysteinyl Leukotriene ELISA EIA-3615 96 Wells 2/2h Prostacyclin (Urinary) ELISA EIA-3108 96 Wells 2h/45 min Prostaglandin E1 ELISA EIA-3092 96 Wells 2h/45 min Prostaglandin E2 ELISA EIA-3031 96 Wells 2h/45 min Prostaglandin E2 High Sensitivity ELISA EIA-3097 96 Wells 18-24/1 h Prostaglandin E2 (HS) ELISA EIA-3525 5 x 96 Wells overnight/1 h New Prostaglandin E2 (PGE2) ELISA EIA-5194 96 Wells 120/30 min New Prostaglandin E2 (PGE2) HS ELISA EIA-5203 96 Wells 15 min/16h/30 min 6-Keto Prostaglandin F1 alpha ELISA EIA-3078 96 Wells 2h/45 min Total-8-iso-Prostaglandin F2 alpha ELISA EIA-3080 96 Wells 2h/45 min Prostaglandin F2 alpha ELISA EIA-3101 96 Wells 2h/45 min 9 alpha, 11 beta Prostaglandin F2 alpha ELISA EIA-3084 96 Wells 2/1h 15-deoxy-delta12,14 Prostaglandin J2 ELISA EIA-3640 96 Wells 18-24/1h Thromboxane B2 ELISA EIA-3105 96 Wells 2h/45 min 11-dehydro-Tromboxane B2 ELISA EIA-4684 96 Wells 120/60 min

Immunoassays 41 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 42

Neuropeptides/Neuropeptide New/Neu: Amyloid Beta Auto-Ab ELISA Amyloid Beta 1-40 (Serum) ELISA

Product / Method Cat No. No. of Tests Incubation time

Adrenomedullin (Human) (DA) RIA* RIA-1622 125 Tests 16-24/16-24h/90 min New Amyloid (Human) Beta 1-40 (Serum) ELISA EIA-5231 96 Wells 180/30/20 min Amyloid Beta 1-42 (Colorimetisch) COL-3995 96 Tests 6,5 h Amyloid Beta Auto-Ab (Serum) ELISA EIA-5099 96 Wells 60/60/30 min Pro-ADM 45-92 (Human) (DA) RIA* RIA-2141 125 Tests 16-24/16-24h/90 min Pro-ADM 153-185 (Human) (DA) RIA* RIA-2142 125 Tests 16-24/16-24h/90 min ADM 1-50 (DA) RIA* RIA-2138 125 Tests 16-24/16-24h/90 min Agouti-related protein (83-132) Amide (DA) RIA* RIA-2626 125 Tests 16-24/16-24h/90 min BDNF (Human) ELISA EIA-5106 96 Wells 120/120/30/20 min Dynorphin A (Porcine) (DA) RIA* RIA-0708 125 Tests 16-24/16-24h/90 min Dynorphin A (1-8)(Porcine) (DA) RIA* RIA-0706 125 Tests 16-24/16-24h/90 min ß-Endorphin (Human) (DA) RIA RIA-3023 100 Tests 18-24/18-24h/15 min ß-Endorphin (Rat) (DA) RIA* RIA-1126 125 Tests 16-24/16-24h/90 min Galanin (Human) (DA) RIA* RIA-1648 125 Tests 16-24/16-24h/90 min Galanin (Porcine) (DA) RIA* RIA-0668 125 Tests 16-24/16-24h/90 min. Galanin (Rat) (DA) RIA* RIA-0667 125 Tests 16-24/16-24h/90 min. Leumorphin (Human) (DA) RIA* RIA-0717 125 Tests 16-24/16-24h/90 min MCH (Melanin Conc. Horm. (Rat) (DA) RIA* RIA-2146 125 Tests 16-24/16-24h/90 min alpha-MSH direct (Melanocyte Stim. Horm.) RIA RIA-3024 100 Tests 20-24h/30-60 min ß-MSH (Human) (DA) RIA* RIA-1142 125 Tests 16-24/16-24h/90 min gamma-MSH (Human) (DA) RIA* RIA-1143 125 Tests 16-24/16-24h/90 min Neurokinin A (DA) RIA* RIA-0692 125 Tests 16-24/16-24h/90 min Neurokinin B (DA) RIA* RIA-0691 125 Tests 16-24/16-24h/90 min Neuropeptide Y (Hum, Rat) (DA) RIA* RIA-1144 125 Tests 16-24/16-24h/90 min Neuropeptide Y (Porcine) (DA) RIA* RIA-0675 125 Tests 16-24/16-24h/90 min Orphanin FQ (Nociceptin) (DA) RIA* RIA-2047 125 Tests 16-24/16-24h/90 min PACAP 27-NH2 (Hum, Rat) (DA) RIA* RIA-1166 125 Tests 16-24/16-24h/90 min PACAP 38 (Human, Rat) (DA) RIA* RIA-1241 125 Tests 16-24/16-24h/90 min Peptide YY (3-36) Specific RIA RIA-4647 125 Tests 24 h/24 h/20 min Peptide YY human RIA RIA-4257 125 Tests 24 h/24 h/20 min Peptide YY (PYY) (Human) (DA) RIA* RIA-1654 125 Tests 16-24/16-24h/90 min Peptide YY (Rat, Porcine) (DA) RIA* RIA-0676 125 Tests 16-24/16-24h/90 min Sarafotoxin SG 6 (DA) RIA* RIA-0659 125 Tests 16-24/16-24h/90 min Substance P ELISA EIA-1635 96 Wells 2/1/1 h Substance P ELISA EIA-3120 96 Wells 2/1h Substance P (DA) RIA* RIA-0693 125 Tests 16-24/16-24h/90 min TAU total ELISA EIA-3723 96 Wells 2/1h/30/60 min TAU total ELISA EIA-3724 192 Wells 2/1h/30/60 min

42 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 43

Thyroid Function New/Neu: Chemiluminescence Immunoassays (CLAS)

Free T4 TSH

Product / Method Cat No. No. of Tests Incubation time

T3 total ELISA EIA-1780 96 Wells 60/20 min T3 total ELISA EIA-4569 96 Wells 30/30/10 min Free T3 ELISA EIA-2385 96 Wells 60/15 min T3 total (CT) RIA RIA-4534 96 Tests 60 min Free T3 (CT) RIA RIA-4201 100 Tests 120 min T4 total (CT) RIA RIA-4533 96 Tests 60 min T4 total ELISA EIA-1781 96 Wells 60/20 min T4 total ELISA EIA-4568 96 Wells 5/80/10 min T4 Dog ELISA (small) EIA-3441 32 Wells 60/15 min T4 Dog ELISA EIA-2492 96 Wells 60/15 min T4 Cat ELISA (small) EIA-3442 32 Wells 60/15 min Free T4 CLA CLA-4659 96 Wells 30/10-15 min Free T4 ELISA EIA-2386 96 Wells 60/15 min Free T4 (CT) RIA RIA-4202 100 Tests 90 min T-Uptake ELISA EIA-3267 96 Wells 60/15 min Thyroglobulin Antigen ELISA EIA-3377 96 Wells 60/60/15 min Thyroglobulin Ab (TG Ab) ELISA EIA-3708 96 Wells 30/15/15/5 min Thyroid Peroxidase Ab (TPO Ab) ELISA EIA-3561 96 Wells 30/15/15/5 min New TPO Ab ELISA EIA-4114 96 Wells 60/30/15 min TSH CLA CLA-4658 96 Wells 30/10-15 min TSH ELISA EIA-4171 96 Wells 10/90/20 min TSH ultrasensitive ELISA EIA-1790 96 Wells 120/20 min TSH (CT) IRMA RIA-4200 100 Tests 90 min TSH Neonatal IRMA RIA-1452 100 Tests 18-24 h TSH Neonatal ELISA EIA-1483 192 Wells 18-24h/60/15 min TSH Receptor Auto Ab ELISA (2 nd generation) EIA-3369 96 Wells 120/20/20/20 min TSH Receptor Auto Ab (3 rd generation) EIA-4834 96 Wells 2 h/25 min

Immunoassays 43 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 44

Saliva Diagnostics/Speichel Analytik

Sensitive ELISAS Supersensitive ELISAS for detection of Free Steroids zur Bestimmung von freien and other parameters in Saliva Steroidhormonen und anderen samples Parametern in Speichelproben

Benefits: Vorteile:

• Non invasive sampling, can be done also by patients • Nichtinvasive Probenahme, auch vom Patienten durchführbar

• Measurement of the free (unbounded) fraction of • Messung der freien (ungebundenen) Fraktion von Steroiden steroids • Bessere diagnostische Relevanz mit repräsentativen und • Much higher diagnostic relevance with reproducible aussagefähigen Ergebnissen gegenüber Serum-Analytik and reliable results, compared to serum analytics • Einfaches und patientenfreundliches Erstellen von Hormon- • Simple and patient-friendly measurement of profilen (Tages-, Monatsprofile) hormone profiles (Diurnal-, monthly profiles) • Keine Probleme bei der Probenahme bei Kleinkindern • Easy sampling in babies and kids • Die Messung von Steroiden • The measurement of steroids in ist auch in der veterinary saliva samples in Veterinärdiagnostik possible without any further ohne spezielle Proben- pre-treatment behandlung möglich New/Neu: Estrone Saliva

Product / Method Cat No. No. of Tests Incubation time

Alpha Amylase Saliva ENZ-5127 96 Wells 3 min Androstenedione Saliva ELISA SLV-4780 96 Wells 60/15 min Cortisol (Salivary) ELISA SLV-2930 96 Wells 60/30 min Cortisol High Sensitive (Salivary) ELISA SLV-4635 96 Wells 60/30 min Cotinin (Saliva) ELISA EIA-3243 96 Wells 30/30 min DHEA Salivary ELISA SLV-3012 96 Wells 60/10 min DHEA-S Saliva SLV-4409 96 Wells 15/15 min Estradiol Salivary ELISA high sensitive SLV-4188 96 Wells 120/15 min New Estrone (Saliva) ELISA SLV-5228 96 Wells on request Estrone (Saliva) CLA CLA-4655 96 Wells 60/30/5-20 min Free Estriol Salivary ELISA SLV-3653 96 Wells 60/15 min Free Estriol (Saliva) CLA CLA-4653 96 Wells 45/20/10-15/20 min IgA Salivary ELISA SLV-4636 96 Wells 60/15 min Lactate Salivary ELISA SLV-4764 96 Wells on request Melatonin Salivary ELISA SLV-4779 96 Wells 16-20h/2h/1h/15/15 min 17 alpha-OH-Progesterone (Saliva) ELISA SLV-3140 96 Wells 60/15 min Progesterone Saliva ELISA SLV-2931 96 Wells 60/15 min Testosterone (Saliva) ELISA SLV-3013 96 Wells 60/30 min Testosterone (Saliva) CLA CLA-4661 96 Wells 60/30/10-15/10-30 min Sali Tubes 100 SLV-4158 100 Tubes/Caps Sali Tubes 500 SLV-4157 500 Tubes/Caps

44 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 45

Oncology/Tumor Diagnosis

New ELISA/CLA:TM-CA 72-4 New ELISA/CLA:TM-Cyfra 21-1 CA 72-4 (Cancer antigen 72-4) was ori- choice for the therapeutic monitoring and Cytokeratin 19 is expressed in most body ginally described as an antigenic determi- follow-up care of gastrointestinal cancer tissues. Cyfra 21-1 levels are therefore ele- nant recognized by B 72.3, a murine mono- patients. Suitable second markers are CA vated in many cancer forms. It is predomi- clonal antibody raised against a membrane 19-9 or CEA. Additionally, CA 72-4 has nantly used for the management of patients extract of mamacarcinoma metastasases. been used as an independent marker for suffering from lung cancer. It is particularly Elevated CA 72-4 levels in serum and plas- the therapeutic monitoring and follow-up helpful in the differential diagnosis of bron- ma have been reported in various malignant care of ovarian cancer patients, in particular chial carcinoma. diseases including carcinomas of pancreas, in CA 125 negative patients. stomach, gall, colon, mamma, ovaries, cervix and endometrium. There is a good correla- New/Neu: tion between CA 72-4 levels and tumor CYR-61 ELISA stage and size. CA 72-4 is the marker of Cripto-1 ELISA L1-CAM ELISA Afamin ELISA HMGB ELISA S100B ELISA

Product / Method Cat No.

New Afamin ELISA EIA-5085 96 Wells 60/60/20 min AFP ELISA EIA-1468 96 Wells 30/10 min AFP IRMA (cubic size) RIA-4385 384 Tests 60/60 min Alpha Subunit IRMA RIA-4538 100 Tests 60 min Bax (Human) ELISA EIA-4487 96 Wells 60/60/30/30 min Bcl-2 (Human) ELISA EIA-4488 96 Wells 60/60/30/30 min BRCA-1 total (Human) ELISA EIA-4489 96 Wells 60/120/30/30 min CA 19-9 (CB) RIA RIA-3934 100 Tests 3/3h CA 19-9 IRMA RIA-5046 96 Tests 30/60 min New TM-CA 19-9 ELISA EIA-5069 96 Wells CA 242 ELISA EIA-4581 96 Wells 120/60/30 min CA 242 ELISA EIA-2082 96 Wells 120/60/30 min CA 15-3 IRMA RIA-4426 96 Tests 90/90 min CA 15-3 (CB) RIA RIA-3935 100 Tests 2/3h New TM-CA 15-3 ELISA EIA-5068 96 Wells CA 72-4 CLA CLA-4730 96 Wells CA 72-4 (CB) RIA RIA-3936 100 Tests 4/18h CA 72-4 RIA RIA-4243 96 Tests 4h/16-20h New TM-CA 72-4 ELISA EIA-5071 96 Wells CA 125 IRMA RIA-4438 96 Tests 120/60 min CA 125 II (CB) RIA RIA-3933 100 Tests 20h New TM-CA 125 ELISA EIA-5072 96 Wells CEA ELISA EIA-1868 96 Wells 60/15 min CEA IRMA RIA-4384 96 Tests 120 min Chromogranin A (CgA) ELISA EIA-4937 96 Wells 60/15/15 min Chromogranin A RIA RIA-4562 100 Tests 20-24h/30-60 min New Cripto-1 ELISA EIA-5109 96 Wells 180/30/20 min CYFRA 21-1 CLA CLA-4731 96 Wells CYFRA 21-1 (CB) RIA RIA-3937 100 Tests 16 h New TM-CYFRA 21-1 ELISA EIA-5070 96 Wells New CYR 61 ELISA EIA-5108 96 Wells 120/30/15 min

Immunoassays 45 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 46

Tumordiagnostik/Onkologie

Product / Method Cat No. No. of Tests Incubation time

Ferritin ELISA EIA-1872 96 Tests 45/20 min Ferritin ELISA EIA-4408 96 Wells 60/10 min Ferritin IRMA RIA-5087 100 Tubes 60 min ßHCG/HCG ELISA EIA-1911 96 Wells 60/15 min Free ßHCG ELISA EIA-4718 96 Wells 30/30/20 min New HMGB1 ELISA EIA-5259 96 Wells 20-24h/120/30 min Kathepsin D (CT) RIA RIA-3747 96 Tests 3 h New L1-CAM ELISA EIA-5074 96 Wells 60/30/15 min ß-2 Microglobulin ELISA EIA-3609 96 Wells 30/15/15 min NSE ELISA EIA-4610 96 Wells 60/15 min NSE ELISA EIA-2353 96 Wells 60/30 min NSE ELISA EIA-4424 96 Wells 60/30 min NSE IRMA RIA-4411 96 Wells 120 min Occult Combo Detect RAP-4637 25 Tests 10 min Osteocalcin (Human) ELISA EIA-3375 96 Wells 120/30 min Osteocalcin IRMA RIA-3651 96 Tests 2h Osteocalcin (Human) (DA) RIA RIA-1542 100 Tests 60/15 min p27 (Human) ELISA EIA-4491 96 Wells 60/60/30/30 min p53 total (Human) ELISA EIA-4632 96 Wells 120/60/30 min PAP ELISA EIA-1566 96 Wells 15/15/15 min PSA equimolar ELISA EIA-1551 96 Wells 60/60/30 min PSA total ELISA EIA-3719 96 Wells 60/20 min PSA total CLA CLA-4657 96 Wells 30/30/10-15 min PSA IRMA (CT) RIA-4895 100 Tests 2h free PSA ELISA EIA-1550 96 Wells 60/30/15 min free PSA ELISA EIA-4189 96 Wells 60/60/15 min free PSA IRMA (CT) RIA-4896 50 Tests 2h S100 B ELISA EIA-4555 96 Wells 90/90/10 min New S100 B ELISA EIA-5169 96 Wells 120/60/30 min SCC ELISA EIA-4457 96 Wells 60/30 min sCD44 (human) ELISA EIA-4876 96 Wells 180/15 min sp185 (HER-2) human ELISA EIA-4877 96 Wells 120/10 min Survivin ELISA EIA-4137 96 Wells 60/60/30/30 min TPA (Tissue Polypeptide Antigen) ELISA EIA-2092 96 Wells 120/15 min TPA (Tissue Polypeptide Antigen) IRMA RIA-3437 100 Tests 4 h TPS ELISA (not for export) EIA-2354 96 Wells 120/20 min TPS IRMA (not for export) RIA-3028 100 Tests 2 h Tumormarker Control CTL-4756 1 x 0,5 ml Tumormarker Control CTL-4755 1 x 0,5 ml UBC ELISA (not for export) EIA-2355 96 Wells 120/15 min UBC (CB) IRMA (not for export) RIA-3029 100 Tests 2h

46 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 47

Infectious Diseases

New/Neu: DRG-NOVUM ELISAS At the end of 2003 DRG has taken Hantavirus (Hantaan) over the assets of NOVUM Diagnosti- Hantavirus (Puumala) ka, Dietzenbach. NOVUM has develo- Hantavirus (Dobrava) ped and manufactured a wide range Borrelia IgG/IgM Line of products to identify and manage Fasciola infectious diseases. Rickettsia conorii IgM Meningitis IgG Now DRG is manufacturing these Chikungunya IgG/IgM ELISAS in the same excellent quality and offers these assays at competitive prices.

Product / Method Cat No. No. of Tests Incubation time

Adenovirus antigen (stool) ELISA EIA-3444 96 Wells 30/5/5/5 min Adenovirus IgA ELISA EIA-3445 96 Wells 60/30/15 min Adenovirus IgG ELISA EIA-3446 96 Wells 60/30/15 min Adenovirus IgM ELISA EIA-3447 96 Wells 60/30/15 min Ascaris lumbricoides IgG ELISA EIA-3817 96 Wells 60/60/15 min Aspergillus fumigatus IgA ELISA EIA-2500 96 Wells 60/30/20 min Aspergillus fumigatus IgG ELISA EIA-2501 96 Wells 60/30/20 min Aspergillus fumigatus IgM ELISA EIA-2502 96 Wells 60/30/20 min Astrovirus (stool) ELISA EIA-4456 96 Wells 60/10 min Avian Influenza A Nucleoprotein Ag Capture EIA-4711 192 Wells 30/45/10 min Bordetella pertussis/toxin IgA ELISA EIA-3449 96 Wells 60/30/15 min Bordetella pertussis/toxin IgG ELISA EIA-3450 96 Wells 60/30/15 min Bordetella pertussis/toxin IgM ELISA EIA-3451 96 Wells 60/30/15 min New Borrelia IgG Line Immunoassay EIA-5300 20 Tests 45/3x5/45/3x5/10 min New Borrelia IgM Line Immunoassay EIA-5301 20 Tests 45/3x5/45/3x5/10 min Borrelia IgG recombinant ELISA EIA-4289 96 Wells 60/30/30 min Borrelia IgM recombinant ELISA EIA-4288 96 Wells 60/30/30 min Anti-Borrelia LIA IgG 20 Tests 5/45/45/10 min Anti-Borrelia Blot IgM 20 Tests 5/45/45/10 min Brucella IgA ELISA EIA-3271 96 Wells 60/30/20 min Brucella IgG ELISA EIA-3455 96 Wells 60/30/15 min Brucella IgM ELISA EIA-3456 96 Wells 60/30/15 min Candida albicans IgA ELISA EIA-3457 96 Wells 60/30/15 min Candida albicans IgG ELISA EIA-3458 96 Wells 60/30/15 min Candida albicans IgM ELISA EIA-3459 96 Wells 60/30/15 min Chagas Disease see Tryponosoma Cruzi Chikungunya IgG ELISA EIA-5102 96 Wells 60/30/30/30/15 min Chikungunya IgM ELISA EIA-5103 96 Wells 60/30/30/15 min Chlamydia trachomatis IgA ELISA EIA-3809 96 Wells 60/30/15 min Chlamydia trachomatis IgA ELISA* EIA-3461 96 Wells 60/30/15 min Chlamydia trachomatis IgG ELISA EIA-3810 96 Wells 60/30/15 min Chlamydia trachomatis IgG ELISA* EIA-3462 96 Wells 60/30/15 min Chlamydia trachomatis IgM ELISA EIA-3811 96 Wells 60/30/15 min Chlamydia trachomatis IgM ELISA* EIA-3463 96 Wells 60/30/15 min

* no CE mark Immunoassays 47 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 48

Infectious Diseases

Product / Method Cat No. No. of Tests Incubation time

Chlam. trachomatis Ag ELISA EIA-3460 96 Wells 10/60/20 min Transportmedium for Chlam. trachom. Ag ELISA EIA-3460 TRANS 95 Vials Swabs for Chlamydia trachom. Ag ELISA EIA-3460 SWAB 100 pcs. Chlamydia pneumoniae IgA ELISA EIA-4160 96 Wells 60/30/15 min Chlamydia pneumoniae IgG ELISA EIA-3912 96 Wells 60/30/15 min Chlamydia pneumoniae IgM ELISA EIA-3913 96 Wells 60/30/15 min Clostridium A+B Ag (stool) ELISA EIA-4203 96 Wells 30/10/10 min CMV IgG ELISA (Cytomegalie Virus) EIA-3808 96 Wells 60/30/15 min CMV IgG ELISA* EIA-3468 96 Wells 60/30/10 min CMV IgG (qual.) ELISA EIA-5153 96 Wells 60/30/15 min CMV IgM ELISA EIA-3823 96 Wells 60/30/15 min CMV IgM ELISA* EIA-3469 96 Wells 60/30/10 min CMV IgG Avidity ELISA EIA-3953 96 Wells 60/30/30/10 min Coxiella burnetii Phase 1 IgG ELISA EIA-5188 96 Wells 60/30/15 min Coxiella burnetii Phase 2 IgG ELISA EIA-5189 96 Wells 60/30/15 min Coxiella burnetii Phase 1 IgM ELISA EIA-5187 96 Wells 60/30/15 min Coxsackie B Virus IgM ELISA EIA-5175 96 Wells 60/60/20 min CRP (C-reactive Protein) ELISA EIA-1952 96 Wells 30/30/10 min CRP (C-reactive Protein) High sensitive ELISA EIA-3954 96 Wells 45/20 min Cryptosporidium Ag (stool) ELISA EIA-3467 96 Wells 30/5/5/5 min Corynebacterium Diphteriae (toxin) IgG ELISA EIA-3466 96 Wells 10/5/5 min Dengue IgG ELISA EIA-3470 96 Wells 60/30/15 min Dengue IgM ELISA EIA-3471 96 Wells 60/30/15 min New Dengue (1-4) IgM capture ELISA EIA-5245 96 Wells 60/60/5 min E.coli 0157 (EHEC) Ag (stool) ELISA EIA-4229 96 Wells 30/30/10 min E.coli Verotoxin Ag (stool) ELISA EIA-4204 96 Wells 30/30/10 min Echinococcus IgG ELISA EIA-3472 96 Wells 60/30/15 min Entamoeba histolytica Ag (stool) (Amebiasis) ELISA EIA-3473 96 Wells 30/5/5/5 min Entamoeba histolytica Ag (stool) ELISA EIA-4454 96 Wells 30/30/10 min Entamoeba histolytica IgG (Amebiasis) ELISA EIA-3474 96 Wells 10/5/5 min Epstein-Barr Virus (EA) IgA ELISA EIA-2516 96 Wells 60/30/20 min Epstein-Barr Virus (EA) IgG ELISA EIA-2517 96 Wells 60/30/20 min Epstein-Barr Virus (EA) IgM ELISA EIA-2518 96 Wells 60/30/20 min Epstein-Barr Virus (EBNA-1) IgA ELISA EIA-2519 96 Wells 60/30/20 min Epstein-Barr Virus (EBNA-1) IgG ELISA EIA-4246 96 Wells 60/60/20 min Epstein-Barr Virus (EBNA-1) IgM ELISA EIA-4247 96 Wells 60/60/20 min Epstein-Barr Virus (VCA) IgA ELISA EIA-4472 96 Wells 60/30/15 min Epstein-Barr Virus (VCA) IgG ELISA EIA-3475 96 Wells 60/60/20 min Epstein-Barr Virus (VCA) IgM ELISA EIA-3476 96 Wells 60/60/20 min Fasciola ELISA EIA-4503 96 Wells 60/30/15 min Flavivirus (West Nile) IgG ELISA EIA-4519 96 Wells 60/30/10 min Flavivirus (West Nile) IgM Capture ELISA EIA-4504 96 Wells 60/60/60/5/10/1 min FSME (see "Tickborne encephalitis virus" next page) Giardia lamblia Ag (stool) (Giardiasis) ELISA EIA-3477 96 Wells 30/30/10 min Haemophilus Influenzae B IgG ELISA EIA-2530 96 Wells 60/60/30 min New Hantavirus (Hantaan) IgG/IgM ELISA EIA-5237 96 Wells 45/45/10 min

48 Immunoassays * no CE mark Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 49

Virologie/Serologie

Product / Method Cat No. No. of Tests Incubation time

New Hantavirus (Puumala) IgG/IgM ELISA EIA-5238 96 Wells 45/45/10 min New Hantavirus (Dbrava) IgG/IgM ELISA EIA- 5239 96 Wells 45/45/10 min HAV Ab ELISA EIA-4233 96 Wells 60/60/20 min HAV IgM (µ-capture) ELISA EIA-4432 96 Wells 60/60/20 min HBc Ab (Screening) ELISA* EIA-4086 96 Wells 60/60/20 min HBc Ab (Screening) ELISA EIA-4872 96 Wells 60/70/20 min HBc IgM* (capture) ELISA EIA-4085 96 Wells 60/60/20 min HBc IgM (capture) ELISA EIA-5143 96 Wells 60/60/20 min Hbe Ag/Ab ELISA EIA-5145 96 Wells 60/60/20 min HBe Ag/Ab ELISA* EIA-4162 96 Wells 60/60/20 min Hbs Ab ELISA EIA-5144 96 Wells 60/60/20 min HBs Ab ELISA* EIA-4135 96 Wells 60/60/20 min HBs Ag ELISA* EIA-4545 96 Wells 120/30 min HBs Ag ELISA EIA-4548 96 Wells 120/30 min Hbs Ag ELISA EIA-5051 192 Wells 120/30 min HBs Ag ELISA* EIA-4134 192 Wells 120/30 min

HBs Ag Confirmation EIA-5150 20 Tests 30 min for use with HBs Ag EIA-4134

HBs Ag Confirmation* EIA-3949 20 Tests 30 min for use with HBs Ag EIA-4134

HBs Ag Confirmation EIA-5151 40 Tests 30 min for use with HBs Ag EIA-5151

HBs Ag Confirmation* EIA-5166 40 Tests 30 min for use with HBs Ag EIA-4134 HCV Ab ELISA* EIA-4543 96 Wells 45/45/15 min HCV Ab ELISA* EIA-3903 192 Wells 45/45/15 min HCV Ab ELISA* EIA-3903 192 Wells 45/45/15 min HCV Ab ELISA EIA-4332 192 Wels 45/45/15 min HCV Ab ELISA EIA-4549 96 Wells 45/45/15 min HCV Ab ELISA* EIA-6063 480 Wells 45/45/15 min HCV Ab ELISA* EIA-5165 480 Wells 45/45/15 min HCV Ab Confirmation* EIA-3970 96 Wells 60/60/20 min HCV Ab Confirmation EIA-5149 96 Wells 60/60/20 min HCV IgG ELISA* EIA-3834 96 Wells 60/30/30 min HCV IgM ELISA* EIA-3908 96 Wells 60/60/20 min HCV IgM ELISA EIA-5148 96 Wells 60/60/20 min HDV Ab ELISA EIA-5152 96 Wells 60/60/20 min HDV Ab ELISA* EIA-4269 96 Wells 90/20 min HDV Ag ELISA EIA-5147 96 Wells 120/60/20 min HDV Ag ELISA* EIA-4268 96 Wells 120/60/20 min HDV IgM ELISA EIA-5146 96 Wells 60/60/20 min HDV IgM ELISA* EIA-4120 96 Wells 60/60/20 min HEV Ab ELISA EIA-4416 96 Wells 45/45/15 min HEV IgM ELISA EIA-4417 96 Wells 60/60/20 min HGV Ab ELISA EIA-4360 96 Wells 30/30/10 min Helicobacter Pylori IgA ELISA EIA-3483 96 Wells 60/30/15 min Helicobacter Pylori IgG (Cag A) ELISA EIA-3484 96 Wells 60/30/15 min Helicobacter Pylori IgM ELISA EIA-2111 96 Wells 30/30/20 min Helicobacter Pylori Ag Stool ELISA EIA-4354 48 Wells 120/20 min Helicobacter Pylori Ag Stool Extraction kit EIA-4355 50 Tests

* no CE mark Immunoassays 49 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 50

Infectious Diseases

Product / Method Cat No. No. of Tests Incubation time

Herpes Simplex 1 IgA ELISA EIA-2532 96 Wells 60/30/20 min Herpes Simplex-1 IgG ELISA EIA-3485 96 Wells 60/30/15 min Herpes Simplex-1 IgM ELISA EIA-3486 96 Wells 60/30/15 min Herpes Simplex 2 IgA ELISA EIA-2533 96 Wells 60/30/20 min Herpes Simplex-2 IgG ELISA EIA-3487 96 Wells 60/30/15 min Herpes Simplex-2 IgM ELISA EIA-3488 96 Wells 60/30/15 min Herpes Simplex 1+2 IgG ELISA EIA-3489 96 Wells 60/30/15 min Herpes Simplex 1+2 IgM ELISA EIA-3490 96 Wells 60/30/15 min HIV 1+2 ELISA* EIA-3491 96 Wells 30/15/15 min HIV 1+2 Ab&Ag* screening ELISA EIA-5167 192 Wells 60/30/30/30 min HIV 1+2 Ab & Ag (Screening) ELISA (4th generation) EIA-4847 192 Wells 60/30/30/30 min Human Papilloma Virus IgG ELISA* EIA-4907 96 Wells 60/60/20 min HTLV I&II Ab (Screening) ELISA* EIA-3905 192 Wells 45/45/15 min HTLV I&II Ab (Screening) ELISA* EIA-4404 192 Wells 450/45/15 min JE (Japanese Encephalitis) IgM ELISA EIA-4505 96 Wells 60/60/5/10 min JE (Japanese Encepahlitis) IgG ELISA EIA-4518 96 Wells 60/60/5/10 min Influenza A IgA ELISA EIA-4242 96 Wells 60/30/15 min Influenza A IgG ELISA EIA-4238 96 Wells 60/30/15 min Influenza A IgM ELISA EIA-4240 96 Wells 60/30/15 min Influenza B IgA ELISA EIA-4239 96 Wells 60/30/15 min Influenza B IgG ELISA EIA-4241 96 Wells 60/30/15 min Influenza B IgM ELISA EIA-4237 96 Wells 60/30/15 min Legionella pneum. Ag (Urine) ELISA EIA-4205 96 Wells 30/10/5 min Leishmania IgG ELISA EIA-3492 96 Wells 10/10/5 min Leptospira IgM ELISA EIA-4715 96 Wells 5/10/10/5 min Lyme Borrelia (recombinant Ag) IgG ELISA EIA-4289 96 Wells 60/30/15 min Lyme Borrelia (recombinant Ag) IgM ELISA EIA-4288 96 Wells 60/3015 min Malaria Ab ELISA EIA-4263 96 Wells 30/30/30 min Malaria Ab ELISA EIA-5048 192 Wells 60/30/30/30 min Malaria Ab ELISA EIA-5411 192 Wells 30/20/10 min Measles Virus IgG ELISA EIA-3495 96 Wells 60/30/15 min Measles Virus IgM ELISA EIA-3496 96 Wells 60/30/15 min Meningitis IgG ELISA EIA-4918 96 Wells 60/60/20 min Mumps IgG ELISA EIA-3497 96 Wells 60/30/15 min Mumps IgM ELISA EIA-3498 96 Wells 60/30/15 min Mycoplasma hominis IgA ELISA EIA-5097 96 Wells 60/30/15 min Mycoplasma hominis IgG ELISA EIA-4559 96 Wells 60/30/15 min Mycoplasma hominis IgM ELISA EIA-4560 96 Wells 60/30/15 min Mycoplasma pneumoniae IgA ELISA EIA-3848 96 Wells 60/30/15 min Mycoplasma pneumoniae IgG ELISA EIA-3499 96 Wells 60/30/15 min Mycoplasma pneumoniae IgM ELISA EIA-3500 96 Wells 60/30/15 min Norovirus ELISA* EIA-4864 96 Wells 60/30/15 min Parainfluenza 1/2/3 IgG ELISA EIA-4349 96 Wells 60/30/20 min Parainfluenza 1/2/3 IgM ELISA EIA-4350 96 Wells 60/30/20 min Parvovirus B19 IgG ELISA EIA-3503 96 Wells 60/30/15 min Parvovirus B19 IgM ELISA EIA-3504 96 Wells 60/30/15 min 50 Immunoassays * no CE mark Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 51

Virologie/Serologie

Product / Method Cat No. No. of Tests Incubation time

Rickettsia conorii IgG ELISA EIA-5297 96 Wells 60/30/10 min Rickettsia conorii IgM ELISA EIA-4613 96 Wells 60/30/10 min Rotavirus Ag (stool) ELISA EIA-3509 96 Wells 60/15 min RSV (Respir. Synth. Virus) IgA ELISA EIA-3506 96 Wells 60/30/15 min RSV (Respir. Synth. Virus) IgG ELISA EIA-3507 96 Wells 60/30/15 min RSV (Respir. Synth. Virus) IgM ELISA EIA-3508 96 Wells 60/30/15 min Rubella Virus IgG ELISA EIA-3857 96 Wells 60/30/15 min Rubella Virus IgG ELISA* EIA-3510 96 Wells 60/30/15 min Rubella Virus IgM µ-capture ELISA EIA-3858 96 Wells 60/30/15 min Rubella Virus IgM ELISA* EIA-3511 96 Wells 60/30/15 min Rubella IgG Avidity ELISA* EIA-3952 96 Wells 60/30/30/10 min Salmonella Ag (stool) ELISA EIA-5412 30/20/10 min Schistosoma mansoni IgG (Billharziosis) ELISA EIA-3872 96 Wells 60/15/15 min Strongyloides IgG ELISA EIA-4208 96 Wells 60/30/15 min Syphilis (Treponema) Trep Screen ELISA EIA-4697 96 Wells 60/30/15 min Syphilis (Treponema) Trep Screen (20 µl sample) ELISA EIA-5054 96 Wells 60/30/15 min Syphilis (Treponema pallidum) IgG ELISA EIA-3517 96 Wells 60/30/15 min Syphilis (Treponema pallidum) IgM ELISA EIA-4267 96 Wells 60/30/15 min Syphilis Ab Screen ELISA EIA-4405 192 Wells 45/45/15 min Taenia solium IgG (Cysticercosis) ELISA EIA-3513 96 Wells 10/5/10 min Tetanus toxin (antitoxin) IgG ELISA EIA-3514 96 Wells 60/30/15 min Toxocara canis IgG ELISA EIA-3518 96 Wells 10/5/15 min Toxoplasma gondii IgA ELISA* EIA-3683 96 Wells 60/30/15 min Toxoplasma gondii IgG ELISA (quantitative) EIA-3863 96 Wells 60/30/15 min Toxoplasma gondii IgG ELISA (quantitative)* EIA-3519 96 Wells 60/30/15 min Toxoplasma gondii µ-capture IgM ELISA EIA-3864 96 Wells 60/60/30 min Toxoplasma gondii IgM ELISA (quantitative)* EIA-3520 96 Wells 60/30/15 min Toxoplasma IgG Avidity ELISA EIA-3950 96 Wells 60/30/30/10 min Treponema Pallidum IgM ELISA EIA-4267 96 Wells 60/30/15 min Treponema Pallidum IgG ELISA EIA-3517 96 Wells 60/30/15 min Treponema Screen ELISA EIA-4697 96 Wells 60/30/15 min Treponema Screen (20 µl) ELISA EIA-5054 96 Wells 60/30/15 min Trichinella spiralis IgG (Trichinosis) ELISA EIA-3521 96 Wells 10/5/5 min Trypanosoma cruzi IgG (Chagas Disease) ELISA EIA-3464 96 Wells 60/30/15 min Tuberculosis IgA ELISA EIA-4250 96 Wells 60/30/20 min Tuberculosis IgG ELISA EIA-4252 96 Wells 60/30/20 min Tuberculosis IgG sensitive ELISA EIA-4508 96 Wells 60/30/20 min Tuberculosis IgM ELISA EIA-4251 96 Wells 60/30/20 min Ureaplasma urealyticum IgA ELISA EIA-5098 96 Wells 60/30/15 min Ureaplasma urealyticum IgG ELISA EIA-4623 96 Wells 60/30/15 min Ureaplasma urealyticum IgM ELISA EIA-4561 96 Wells 60/30/15 min Varicella zoster Virus IgA ELISA EIA-3522 96 Wells 60/30/15 min Varicella zoster Virus IgG ELISA EIA-3523 96 Wells 60/30/15 min Varicella zoster Virus IgM ELISA EIA-3524 96 Wells 60/30/15 min West Nile Virus IgG ELISA EIA-4519 96 Wells 60/60/5/10 min West Nile Virus IgM Capture ELISA EIA-4504 96 Wells 60/60/60/5/10/1 min Yersinia enterolitica IgA ELISA EIA-2566 96 Wells 60/30/20 min Yersinia enterocolitica IgG ELISA EIA-2567 96 Wells 60/30/20 min Yersinia enterocolitica IgM ELISA EIA-2568 96 Wells 60/30/20 min * no CE mark Immunoassays 51 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 52

Vitamines/Vitamine New/Neu: Vitamin Analysis without HPLC Microbiological procedure to determine biologically active vitamins in human and veterinary samples saver time and money

Vitamin C (Colorimetric test) Niacin Vitamin B1 Pantothenic acid Vitamin B2 Vitamin B6 Folic-Acid Vitamin B12 Biotin

Product / Method Cat No. No. of Tests Incubation time

Biotin Bio-Assay BIO-4884 96 Wells 48 h Folic Acid Bio-Assay BIO-4886 96 Wells 48 h Niacin Bio-Assay BIO-4882 96 Wells 48 h Panthothenic acid Bio-Assay BIO-4881 96 Wells 24 h Vitamin B1 (Thiamin) Bio-Assay BIO-4880 96 Wells 24 h Vitamin B2 (Riboflavin) Bio-Assay BIO-4887 96 Wells 48 h Vitamin B6 (Pyridoxin) Bio-Assay BIO-4885 96 Wells 48 h Vitamin B12 Bio-Assay BIO-4883 96 Wells 48 h Vitamin B 12 Folic Acide RIA-1990 100 Tests 10/10/80 min Vitamin C ENZ-4888 96 Wells 3h/20 min 1.25 (OH) 2 Vitamin D ELISA EIA-4193* 96 Wells 18h/1h/30 min 1.25 (OH) 2 Vitamin D (CT) RIA RIA-4782* 48 Tests 15-20h/15 min 25 OH Vitamin D ELISA EIA-3153 96 Wells 3/1 h/20-30 min 25 OH Vitamin D ELISA EIA-4116 96 Wells 120/30/30 min New 25 OH Vitamin D (total) ELISA EIA-5396 96 Tests 30/90/20 min New 25 OH Vitamin D (total) RIA RIA-5292 96 Tests 120 min 25 OH Vitamin D (CT) RIA RIA-2993 96 Wells 2 h * please ask for accessories

52 Immunoassays Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 53

Growth Factors

DRG IGF-1 600 ELISA DRG TGF-ß1 ELISA Insulin-like growth factor I (IGF-1) is a poly- Transforming Growth Factor ß1 (TGF-ß1) peptide of 70 amino acids (7650 daltons). is a 25kDa homodimer composed of two The molecule shows approximately 50% 12.5kDa subunits joined by disulfide bonds. sequence homology with Proinsulin and has This molecule is produced by a number of a number of biological activities similar to cells and tissue types, e.g. trombocytes, insulin. The level of IGF-1 correlates with bone tissue, placenta and kidneys. With res- age. The measurement of serum IGF-1 is of pect to the immune system, TGF-ß1 inhibits recognized value in children with growth T and B cell proliferation and acts as an disorders and in the diagnosis and monito- anti-inflammatory molecule both in vitro ring of acromegaly. and in vivo. TGF-ß1 inhibits macrophage maturation and activation. Elevated TGFß-1 levels have been observed in T-cell leukemia, glioblastomas, AIDS and other diseases. Also available DRG TGF-ß2 ELISA.

Product / Method Cat No. No. of Tests Incubation time

EGF (Human) ELISA EIA-3969 96 Wells 120/30/30 min Growth Hormone (Rat/Mouse) ELISA EIA-4614 96 Wells 90/60/30/20 min New hGH Urinary IRMA RIA-5232 25 Tests 18-24h IGF-1 600 ELISA EIA-4140 96 Wells 120/60/30 IGF-1 (Somatomedin C) IRMA RIA-4702 96 Tests 30 min/overnight IGF-1 direct IRMA RIA-4701 96 Tests 30 min/2 h IGF-I (Somatomedin C) IRMA RIA-1633 100 Tests 3h IGF-1 direct IRMA RIA-2320 100 Tests 2h IGF-1 (Rat) ELISA EIA-2984 96 Wells 60/30/30 min IGF-I (Rat) (DA) RIA RIA-2018 100 Tests 3h/20 min IGF-1, free, IRMA RIA-2321 100 Tests 4h IGF-1, free, ELISA EIA-2328 96 Wells 60/30/10 min IGF-2 ELISA EIA-3285 96 Wells 120/60/10 min IGF-2, direct, IRMA RIA-2019 100 Tests 3h/60min IGF-2 IRMA RIA-2322 100 Tests 3h/1h IGF BP1 ELISA EIA-3432 96 Wells 60/30/10 min IGF BP1 (PP12) ELISA EIA-3780 96 Wells 60/15 min IGF BP1 IRMA RIA-2020 100 Tests 4/18-22h IGF BP3 ELISA EIA-5049 96 Wells 120/30 min IGF BP3 IRMA RIA-4732 96 Tests 120 min IGF BP3 IRMA RIA-2022 100 Tests 18-24 h IGF BP6 (DA) RIA RIA-2323 100 Tests 18-22h/30 min TGF-1 (Rat) (DA) RIA* RIA-0696 125 Tests 16-24/16-24h/90 min TGF ß1 ELISA EIA-1864 96 Wells 3/2h/45/45/15 min TGF ß2 ELISA EIA-2396 96 Wells 3/2h/20/10 min VEGF (human) ELISA EIA-4819 96 Wells 120/60/30 min VEGF-A (human) ELISA EIA-4826 96 Wells 3 h/1 h/10 min VEGF-C (human) ELISA EIA-4825 96 Wells 120/60/10 min sVEGF-1 (Receptor-1) ELISA EIA-4822 96 Wells 120/60/20 min

Immunoassays 53 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 54

Equipment Configuration

Reader Equipment configuration for evaluation of MTPL-ELISA’s Take the advantage of the microtiterplate technology. DRG Instruments GmbH offers an efficient equipment configuration for your laboratory, containing MTPL Reader (including software for evaluation of your microtiterplate ELISA’s), as well as a matrix printer. Cat-No.

MTPL-Reader „E-LizaMat“ 3000 ELM-3000

- Fully automatic -High precision in measuring (+/- 1 %) -Integrated interference filters (405, 450, 492, 630 nm) -Integrated shaker -Integrated software -Bichromatic Measuring -RS 232 interface

MTPL-Reader „E-LizaMat“ 3200

Same features as E-LizaMat 3000, but with integrated Thermo-Printer ELM-3200

MTPL-Strip Reader „E-LizaMat“ 2000

ELM-3241 Features: - Accepts all types of strips -Automatic strip transportation -Bichromatic optics. Standard model includes four filters -Easy to use with step-by-step prompting -On-Board graphics printing -Calculates results automatically -Large non-volatile memory stores more than 50 user-entered tests -Standard model includes one 3 x 12 strip carrier for break-apart microwells

Option and Accessories -Six Filter Visible and UV options available -1904 CASE durable padded carrying case with reinforced corners -Dri-Dye®-Check Strips for verifying accuracy, linearity, and repeatability -Optional 3 x 8 strip carrier for non-break-apart microwell strips.

MTPL Incubator / Shaker Cat-No.

MTPL-Incubator/Shaker E-LizaMat 1500 ELM-3961

-Holds two 96 well microplates -Digitally controlled 8-speed shaker with orbital mixing form 575 to 1500 µpm -Temperature adjustable from ambient to 40°C with resolution of 0.1°C -Digital timer controls shaking of can be operated independently. Solely as a timer -Compact and easy to operate -Outer tinted cover provides further insulation an protection from light

54 Equipment Configuration Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 55

Equipment Configuration Washer Cat-No.

Microtiterplate Washer, manual version TR-717

-For dispensing of wash solution from a container bottle -Includes an 8-port manifold -Screw-in adapters allow conversion to different container sizes

DRG-3100 Easy Wash Mikrotiter ELM-2625 Washer

-Economical hand-held microwell washer for the low volume laboratory -Compact, easy to use and maintain. -Wash and Waste bottles included with an 8-probe manifold

DRG-878 Multy Wash Mikrotiterplate ELM-2624 Washer automatic version

-Full or partial row washing of flat, round and V-bottom plates and strips -Up to 50 user-programmable protocols -6 factory programmed wash and rinse modes - All bottles, tubing, aerosol shield and 8 probe manifold (aspirate and dispense heads included)

ELISA Analyzer Cat-No.

E-LizaMat 8882 ELM 8882 Fully automated 2 plate ELISA processor able to operate the dispense, incubation, reading, data processing and storage of results.

Benefits • Open System • 80 Samples • 8 Different Assays • 2 Microtiter Plates • Autodilution in one Session Technical Features Sample racks 80 sample tubes of 13 mm Dilution rack 92 positions Reagents holder modular racks to hold calibrators, controls and reagents for 8 methods on line Liquid reservoirs external tanks equipped with level sensors; 2 washing buffer Microtiter plates 2 plates (96 wells) with incubation capability, from room temperature to 45°C Dispensing system 1 aspirating-Dispensing probe with X-Y-Z movement; dilution system with a syringe of 1000 µl, Washing system two 8 nozzle on line manifolds with automatic adaptation forthe different micro-plates height Washing Residual volume < 3 µl Washing inaccuracy CV < 5 % with 300 µl Reading system 8 independent photometric channels for mono and bichromatic reading Optical filters 2 filters (450 and 630 nm); 2 more on request (max. 4 filters) Reading inaccuracy ± 1 % from 0.000 to 1.500 OD; ± 2 % from 1.500 to 3.000 OD Dispensation from 8 ml with 1µl resolution, inaccuracy ± 1 % with 100 µl Software Windows 98 and XP operating system, to set up the work list, patient reports and results filing; calibration curves storage for each carried-out test Power requirements 230 / 115 VAC, 50-60 Hz, 500 W Measurements cm 79 x 61 x 65 h Weight 76 Kg Optional Bar code reader for sample identification

Equipment Configuration 55 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 56

Open Walk-away System ELISA Analyzer Cat.-No.

E-LizaMat 8884 ELM 8884

Fully automated 4 plate ELISA processor able to operate the dispense, incubation, reading, data processing and storage of results.

Benefits • Open System • 180 Samples • 10 Different Assays in one Session • 4 Microtiter Plates • Autodilution • 2 Independent Needles for fast pipetting (X-Y-Z)

Technical Features Sample racks 180 sample tubes of 13 mm Predilution rack 1 tray with 195 tubes Reagents holder modular racks to hold calibrators, controls and reagents for 10 methods on line Liquid reservoirs external tanks equipped with level sensors; 4 washing buffer bottles Microtiter plates 4 standard plates (96 wells) with incubation capability, from room temperature to 45°C Dispensing system X-Y-Z movement with 2 independent needles; each one equipped with its own liquid sensor Washing system two 8 nozzle on line manifolds able to adapt itself for the different micro-plates height Reading system 8 independent photometric channels for mono and bichromatic reading Optical filters 2 filters (450 and 630 nm); 2 more on request (max. 4 filters) Reading inaccuracy ± 1 % from 0.000 to 1.500 OD; ± 2 % from 1.500 to 3.000 OD Dispensation from 8 µl to 1000 µl; 1µl resolution, inaccuracy ± 1 % with 100 µl Software Windows 2000 and XP operating system, to set up the work list, patient reports and results filing; calibration curves storage for each carried-out test. LIS interface. Communication port USB Power requirements VAC 230/115, Hz 50-60, W 600 Measurements cm 115 x 65 x 65 Weight 103.5 Kg Optional Bar code reader for sample identification

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Equipment Configuration 57 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 58

Disposables for laboratory use

Product Cat No. Quantity

Buffer A (1 % Trifluoroacetic acid) RIK BA-1 500 ml Buffer B (60 % Acetonitril in 1 % Trifluoroacetic acid) RIK BB-1 100 ml C18 Columns, SPEC-3ML-C18 AR 532-19-30 100

DRG Labpette (10 µl fix) MS 110687 DRG Labpette (20-200 µl) MS 171089 Eppendorf Multipette ED 4780 Eppendorf Varipette (10-100 µl) ED 4710 Micro Celite Columns, System I ELE-2058 10 Micro Celite Columns, System II ELE-2059 10 Micro Celite Columns, System III ELE-2060 10 Reaction caps (1,5 ml) ED 3810 500 Ritips 0,5 ml RI 850223 100 Ritips 1,25 ml RI 850224 100 Ritips 12,5 ml RI 850227 100 Ritips 2,5 ml RI 850225 100 Ritips 25 ml RI 850228 100 Ritips 5 ml RI 850226 100 Ritips 50 ml RI 850229 100 Round Bottom Tubes (12 x 75 mm) GR 115101 250 SALI-TUBES 500 SLV-4157 500 SALI-TUBES 100 SLV-4158 100 Solid Phase Extraction Vaccum System TL 580 1 Set Vacuum Manifold (for 12 Extraction tubes) TL 581 1 Yellow Eppendorf-Pipette Tips (for 10-200 µl) EDO 3004 500

58 Disposables for laboratory use Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 59

Controls/Kontrollen Controls Product Cat.-No. Quantity

Diabetes antigen Control, 2 levels for human Insulin EIA-2338 2 x 0,5 ml

Diabetes antigen Control, Mammalian EIA-2746 2 x 0,5 ml (for bovine, rat, porcine, sheep Insulin) 2 levels

Fertility Control Sera (Human), 3 levels BRC-480-5 12 x 5 ml Immunoassay Control Sera, Level I, II, III 4 vials per level, 12 vials in total BRC-370-5 12 x 5 ml

Proinsulin Control Sera, 2 levels EIA-2061 2 x 1 ml

New Rat Control CTL-5262 2 x 1 ml RIA Control Sera, SET 1, Steroid and Thyroid-Control RIA-0230 3 x 5 ml

RIA Control Sera, SET III RIA-0231 3 x 5 ml TDM and Immunoassay Control Sera, Level I, II, III 2 vials per level RIA-0337 6 x 5 ml

Tumor Marker Control CTL-4756 1 x 0.5 ml Tumor Marker Control CTL-4755 1 x 0.5 ml Tumor Marker Control Sera, 2 levels BRC-580-2 2 x 3 x 2 ml Tumormarker control sera, 2 Levels (low/high) RM 16 4 x 3 ml

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Veterinary Diagnostics ELISAS/Rapid Screen Tests Feline (Cat) Product Cat No. No. of Tests

FIV p24/p17 (Immunodeficiency Virus) Ab EIA-2463 96 Wells FPV (Feline Parvovirus) antigen Faeces EIA-2466 96 Wells FPV (Feline Parvovirus) antibodies EIA-2467 96 Wells FCoV (Feline Corona Virus: FIP Disease) EIA-2468 96 Wells FeLV Ag (Feline Leukaemia Virus) RAP-4816 6 Tests FeLV Ag (Feline Leukaemia Virus) RAP-2740 24 Tests

FeLV Ag Whole Blood RAP-4814 6 Tests FeLV Ag Whole Blood RAP-4815 24 Tests FeLV-p27 (Leukaemia Virus) antigen EIA-2469 96 Wells

FeLV-gp70 (Leukaemia Virus) ab, virus coated EIA-2470 96 Wells FHV (Feline Herpes Virus) antibodies EIA-2472 96 Wells FCV (Feline Calici Virus) antibodies EIA-2473 96 Wells

Feline Chlamydia antibodies EIA-2474 96 Wells Feline T4 total EIA-3442 32 Wells FIV Ab (Feline Immunodeficiency Virus) RAP-4801 6 Tests FIV Ab (Feline Immunodeficiency Virus) RAP-4821 24 Tests FIV Ab Whole Blood RAP-4817 6 Tests FIV Ab Whole Blood RAP-4818 24 Tests

FIV Ab/FeLV Ag Combi RAP-4813 6 Tests Parvovirus dog/cat RAP-4806 6 Tests Parvovirus dog/cat RAP-4058 24 Tests

Canine (Dog) Product Cat No. No. of Tests

C-reactive Protein Canine Quantitative EIA-4694 96 Wells Borrelia burgdorferi Canine Ab EIA-4794 96 Wells

CPV (Parvo Virus) IgG antibodies Faeces EIA-2475 96 Wells CPV (Parvo Virus) IgM antibodies Faeces EIA-2476 96 Wells CPV (Parvo Virus) antigen EIA-2477 96 Wells CDV (Distemper Virus) IgG antibodies EIA-2478 96 Wells CDV (Distemper Virus) IgM antibodies EIA-2479 96 Wells CAV (Adeno Virus) IgG antibodies EIA-2480 96 Wells CHV (Herpes Virus) IgG antibodies EIA-2481 96 Wells

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Veterinary Diagnostics ELISAS/Rapid Screen Tests Canine (Dog) Product Cat No. No. of Tests

CCV (Corona Virus) IgG antibodies EIA-2482 96 Wells CCV (Corona Virus) IgM antibodies EIA-2483 96 Wells CRP (C-reactive peptide) RAP-4800 6 Tests CRP (C-reactive peptide) RAP-4799 24 Tests FSH Canine EIA-4536 96 Wells Heartworm antigen Canine EIA-4795 96 Wells Heartworm RAP-4803 6 Tests Heartworm RAP-4802 24 Tests Insulin Canine EIA-4749 96 Wells Leishmania Ab Canine EIA-4796 96 Wells Parvovirus dog/cat RAP-4806 6 Tests Parvovirus dog/cat RAP-4058 24 Tests New Prolactin canine ELISA EIA-5222 96 Wells Rabies IgG antibodies, virus based EIA-2486 96 Wells RabiesRabies IgMKits antibodies, for humans virus based EIA-2487 96 Wells RFProduct (Rheumafactor) CatRAP-4811 No. 6No. Tests of Tests RF (Rheumafactor) RAP-4812 24 Tests Rabies Virus Glycoproteins ELISA EIA-2489 96 Wells CanineRabies Virus Parainfluenza Nucleoproteins Type 5 Ab ELISA EIA-2491EIA-2490 96 Wells Dog T4 ELISA EIA-2492 96 Wells Dog T4 ELISA EIA-3441 32 Wells New TSH (canine) ELISA EIA-5224 96 Wells

Rabies Kits for humans Product Cat No. No. of Tests

Rabies Virus Glycoproteins ELISA EIA-2489 96 Wells Rabies Virus Nucleoproteins ELISA EIA-2490 96 Wells

Bovine (Cow) ELISA Product Cat No. No. of Tests

Brucella antibodies EIA-2497 96 Wells BLV (Bovine Leukemia) p24/p51 MCA based (serum) EIA-2495 192 Wells BLV p24/gp51 antibodies, MCA based (milk) EIA-2496 192 Wells BLV p24 Blocking Ab MCA based EIA-3159 192 Wells Corona Virus RAP-4798 6 Tests Corona Virus RAP-4797 24 Tests IBR Blocking antibodies, 3 steps high sensitivity EIA-3160 96 Wells Insulin Bovine EIA-4748 96 Wells Leptospira hardjo antibodies, MCA based EIA-2498 96 Wells Parainfluenza 3 (P13) Bovine EIA-4429 96 Wells Veterinary Diagnostics 61 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 62

Veterinary Diagnostics ELISAS/Rapid Screen Tests Equine (Horse) ELISA Product Cat No. No. of Tests

Estradiol EIA-2693 96 Wells New Estrone 3-sulfat (Equine) ELISA EIA-5223 96 Wells IGF-1 Equine ELISA EIA-3982 96 Wells Insulin Equine ELISA EIA-4748 96 Wells Pregnant Mare Serum Gonadotropin (PMSG) EIA-1298 96 Wells PMSG (Pregnant Mare Serum Gonadotr.) RAP-4808 6 Tests PMSG (Pregnant Mare Serum Gonadotr.) RAP-4807 24 Tests New PMSG (Pregnant Mare Serum Gonadotr.) EIA-5135 96 Wells

Porcine (Pig) ELISA Product Cat No. No. of Tests

ADV (Aujetzky s Disease) Ig antibodies EIA-2493 96 Wells ADV Porcine (Aujetzky s Disease Virus) 6 Tests ADV Porcine (Aujetzky s Disease Virus) 24 Tests New CRP (Porcine) ELISA EIA-5192 96 Wells Insulin Porcine ELISA EIA-4747 96 Wells

Avian (Chicken) ELISA Product Cat No. No. of Tests

ALV (Avian Leukose Virus) p27 antigen EIA-2499 96 Wells Many of the DRG human Steroid ELISAs were successfully used in different species (sample extraction protocol is available from DRG), e.g. for:

Estradiol EIA-2693 96 Wells Cortisol EIA-1887 96 Wells Progesterone EIA-1561 96 Wells Testosterone EIA-1559 96 Wells

Other human steroid ELISAs available from DRG: Androstenedione, Corticosterone, DHEA-s, DHEA, Free Estriol, 17 OH Progesterone, Free Testosterone, Dihydrotestosterone

All species Product Cat No. No. of Tests

Influenza Ag RAP-4805 6 Tests Influenza Ag RAP-4804 24 Tests Rotavirus Ag Faeces RAP-4810 6 Tests Rotavirus Ag Faeces RAP-4809 24 Tests

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Rapid Screen Tests

Product Cat No. No. of Tests Method

Amphetamines (FDA approved) RAP-2835 50 Cassette Amphetamines (FDA approved) RAP-2834 50 Dipstick Barbiturates (FDA approved) RAP-3009 50 Cassette Barbiturates (FDA approved) RAP-3005 50 Dipstick Benzodiazepines (FDA approved) RAP-3004 50 Dipstick Benzodiazepines (FDA approved) RAP-3008 50 Cassette Benzodiazepine Drug Screen Rapid Test RAP-4916 50 5 min Chagas Ab Simple WB Rapid Test RAP-5399 20 Cassette 10 min Chagas Ab Strip Rapid Test RAP-5400 20 Dipstick 10 min Chlamydia Ag Rapid Test RAP-4722 20 13 min Cocaine (FDA approved) RAP-2838 50 Dipstick Cocaine (FDA approved) RAP-2839 50 Cassette CRP Rapid Rest RAP-4168 20 15 min Cryptosporidium Ag Simple Rapid Test (stool) RAP-5101 20 Cassette 5 min Cryptosporidium Ag Strip Rapid Test (stool) RAP-5402 20 Dipstick 3/1/5 min Crypto/Giardia Ag Simple Rapid Test (stool) RAP-5403 20 Cassette 10 min Crypto/Giardia Ag Strip Rapid Test (stool) RAP-5404 20 Dipstick 3/1/10 min Dengue IgG/IgM Cassette Test RAP-4290 50 Cassette Dengue Rapid Test RAP-4894 25 15 min Drug Screen Pro 5 Panel 1 RAP-3002 5 Device (AMP/COC/OPI/PCP/THC) Drug Screen Pro 5 Panel 2 RAP-3003 5 Device (AMP/COC/MET/OPI/THC) Entamoeba Ag Simple Rapid Test (stool) RAP-5405 20 Cassette 5/5 min Entamoeba Ag Strip Rapid Test (stool) RAP-5406 20 Cassette 5/5 min Giardia Ag Simple Rapid Test (stool) RAP-5407 20 Cassette 5 min Giardia Ag Strip Rapid Test (stool) RAP-5408 20 Dipstick 3/1/5 min Gonorrhoe Rapid RAP-4867 10 20 min H. Pylori Ag Cassette RAP-4751 25 Cassette H. Pylori Ag Dipstick RAP-4752 25 Dipstick H. Pylori Combo (Whole Blood/Serum) RAP-2734 50 Cassette HBs Ag RAP-4396 25 Cassette HCG Rapid Screen RAP-3151 50 Cassette HCV RAP-4753 20 Cassette HCV* RAP-7063 25 Dipstick HCV RAP-4397 25 Cassette HIV Rapid RAP-4769 1 5 min HIV 1+2 Ab Test RAP-5398 50 Cassette 10 min Infectious Mononucleosis RAP-3060 1 Influenza A H1N1 RAP-5105 25 5 min Influenza Ag A/B/H1N1 RAP-5133 10 10 min Leishmania Detect Rapid Test RAP-2906 25 10 min LH Rapid Screen RAP-3176 25 Cassette Malaria Combo RAP-5110 25 20 min Malaria Pf/Pv Cassette Test RAP-4285 50 Cassette

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Rapid Screen Tests

Product Cat No. No. of Tests Method

Malaria P.f. Strip Test RAP-4401 25 Dipstick Malaria P.f. Cassette Test RAP-4402 25 Cassette Malaria Ag Combo Cassette Test RAP-4403 25 Cassette Marijhuana (THC) (FDA approved) RAP-2840 50 Dipstick Produkt Bestell-Nr. Preis (EURO) Bestimmungen Methode MetamphetaminesProduct (FDA approved) RAP-2836Cat No. Price (EURO) 50No. of Tests DipstickMethod Metamphetamines Drug Screen Rapid Test RAP-4915 50 5-10 min Methadone (FDA approved) RAP-3006 50 Dipstick Methadone (FDA approved) RAP-3010 50 Cassette Morphine/Opiates Drug Screen Rapid Test RAP-4917 50 5 min Mycobacterium Tuberculosis IgG Cassette RAP-5089 50 10 min Myoglobin Whole Blood RAP-3372 20 Cassette Mouse Isotyping Test RAP-4461 10 5-10 min Myoglobin/CK-MB/Troponin 1 Combo Test RAP-4443 20 10 min Occult-Detect (FDA approved) (CE-marked) RAP-4236 20 Cassette Occult Detect Advanced Rapid Test RAP-4723 12 8 min Occult Detect Eco-Pro Rapid Test RAP-4721 25 10 min Opiates (FDA approved) RAP-2831 50 Cassette Occult-Detect (FDA) (CE-marked) RAP-4236 20 Opiates (FDA approved) RAP-2830 50 Dipstick Phencyclidine (PCP) (FDA approved) RAP-2832 50 Dipstick Phencyclidine (PCP) (FDA approved) RAP-2833 50 Cassette PSA (Serum) RAP-3373 50 Cassette PSA (Serum Whole Blood) CE RAP-4330 40 Cassette Rheumatoid Factor (RF) Cassette RAP-4445 25 6 min Rotavirus Ag Simple Rapid Test (stool) RAP-5409 20 Cassette 5 min Rotavirus Ag Strip Rapid Test (stool) RAP-5410 20 Dipstick 3/1/5 min SLE (S. Lupus) Latex RAP-2615 50 Syphilis Rapid Test RAP-4736 20 10 min Syphilis Cassette Test RAP-4286 50 Cassette Syphilis Strip Test RAP-4291 50 Dipstick Syphilis Strip Test RAP-4357 25 10-20 min Syphilis Cassette Test RAP-4358 25 10-20 min TB Screen Cassette Test RAP-4284 50 Cassette Active TB Detect Rapid Test RAP-4506 25 10 min Troponin 1 Whole Blood RAP-3374 20 Cassette Troponin I Serum RAP-4166 20 15 min Troponin 1 / Myoglobin Cassette Test RAP-4442 20 15 min Troponin 1 Rapid Test Cassette RAP-5138 20 10 min Tricyclic Antidepressants (TCA) RAP-3007 50 Dipstick Trypanosoma Detect Rapid Test RAP-4517 25 15 min Tuberculosis IgM/IgG Cassette RAP-5090 50 10 min Tuberculosis (TB) Rapid Test RAP-4758 25 15 min Tubex TF (Thyvoid Fever) RAP-4724 30 10 min New UBC (Urinary Bladder Cancer) RAP-5235 10 5-15 min

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TOXI-LAB® 65 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 66

DRG Drug Screening TOXI-LAB® Drug Identificafion Systems-Detection and Identification of more than 700 drugs from urine, serum or gastric speciments in less than 1 hour.

• Standardized Thin Layer Chromatography • Reproducible, analyte specific results • Drug compendium for quick, accurate and reliable drug identification • Intl. Version of the drug compendium • Proficiency Service • Liquid/liquid Extractions for DC/HPLC/GCMS

® Thin-Layer Chromatography TOXI•LAB Products and Accessories

Accessories TOXI-LAB AB 1 Module I, Workstation / Storage Tray TOXI-LAB AB System is a unique and rapid 1 Module II, Workstation thin-layer chromatographic system designed 1 Module III, Ultraviolet Light Unit for broad spectrum drug detection and drug 1 Drummond Microdispenser confirmation. 1 Custom Electric Warmer The Initial TOXI-LAB AB System comes com- 1 Heat Gun plete with hardware and supplies for TOXI-LAB 1 Heat Gun Holder A (100 tests) for the detection of organic base 1 Ultraviolet Light and neutral drugs and TOXI-LAB B (100 tests) 1 Ammonium Hydroxide Vial with Cap for the detecton of barbiturates and some 1 Omega-12 Extraction Solvent Concentrator other acidic/neutral drugs. and Screen Cat. No. TL 100AB-100 1 Chromatograhy Jar with Cap 4 Stock Reagent Bottles 2 Developing Solution Bottles Supplies 6 Dipping Jars with Special Caps 100 TOXI GRAMS A 1 Standoff Jar 100 TOXI GRAMS B 1 Extra Storage Jar Cap 100 TOXI GRAMS Blank A 1 Forceps 100 TOXI GRAMS Blank B 3 Disc-Handling Pins 100 TOXI TUBES A 2 TOXI RACK 3 Sets 100 TOXI TUBES B 500 Disposable Concentration Cups 200 TOXI DISCS Blank A 200 TOXI DISCS Blank B Reference Aids 2 Vials TOXI DIP A-3 Reagent Concentrate 2 Sets TOXI DIP B Reagent Concentrates 1 TOXI-LAB AB Instruction Manual 6 TOXI CONTROLS, one each of 1, 2, 3, 1 TOXI-LAB Drug Compendium and 5; two each of 19 1 Set TOXI-LAB Training Programs 0.5 Liter Ethyl Acetate, TOXI-LAB Grade (2 Programs in Set) 100 Worksheets A 100 Worksheets B Services Basic Workshop

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DRG Drug Screening TOXI-LAB A-PLUS TOXI-LAB A-PLUS is a rapid thin-layer chromatographic method for the detection and identification of basic and neutral drugs. This initial System is complete with hardware and supplies for those laboratories who do not currently have the TOXI-LAB AB System and require high volume throughput. Cat. No. TL400A-11

Supplies (Accessories cont ‘d) 50 TOXI GRAMS Blank A-PLUS 1 TOXI-LAB Chromatography Tank and Lid 100 TOXI TUBES A 1 Developing Solution Bottle 100 TOXI DISCS Blank A 1 Stock Reagent Bottle (A-3) 50 TOXI DISCS A-1 1 TOXI DIP A-1 Reagent Standoff Jar (Large) 50 TOXI DISCS A-2 1 TOXI DIP A-2 Reagent Tank and Lid

50 TOXI DISCS A-3 1 TOXI DIP H2O Reagent Tank and Lid 50 TOXI DISCS A-4 1 TOXI DIP A-3 Reagent Tank and Lid 6 Vials TOXI DIP A-3 Reagent Concentrate 3 TOXI DIP Chromatogram Stands 500 Disposable Concentration Cups 1 Forceps 6 TOXI Controls, one each of 1, 2, 3 and 5; 3 Disc-Handling Pins two each of 19 0.5 Liter Ethyl Acetate, TOXI-LAB Grade 50 TOXI GRAMS PLUS Worksheets Reference Aids 1 TOXI-LAB AB Instruction Manual 1 TOXI-LAB Drug Compendium Accessories 1 Set TOXI-LAB Training Programs (2 Programs in Set) 1 Module I, Workstation / Storage Tray 1 Custom Electric Warmer Services 1 Heat Gun Basic Workshop 1 Heat Gun Holder 1 Ammonium Hydroxide Vial with Cap 1 Omega-12 Extracton Solvent Concentrator and Screen

TOXI-LAB B-PLUS TOXI-LAB B-PLUS is a rapid thin-layer chromatographic method for the detection and identification of acidic and neutral drugs. This initial System is complete with hardware and supplies for those laboratories who do not currently have the TOXI-LAB AB System and require high volume throughput. Cat. No. TL400B-11 (Accessories con ‘t) Supplies 1 Heat Gun Holder 50 TOXI GRAMS Blank B-PLUS 1 Ammonium Hydroxide Vial with Cap 100 TOXI TUBES B 1 Omega-12 Extracton Solvent Concentrator 100 TOXI DISCS Blank B and Screen 50 TOXI DISCS B-1 1 TOXI-LAB Chromatography Tank and Lid 50 TOXI DISCS B-2 1 Developing Solution Bottle 50 TOXI DISCS B-3 3 Stock Reagent Bottle (B-1, B-2, B-3) 50 TOXI DISCS B-4 1 TOXI DIP B-1 Reagent Tank and Lid 6 Vials TOXI DIP B Reagent Concentrate 1 TOXI DIP B-2 Reagent Tank and Lid (B-1, B-2, B-3) 1 TOXI DIP B-3 Reagent Tank and Lid 500 Disposable Concentration Cups 1 TOXI DIP Chromatogram Stand 2 TOXI Controls, one each of 3 and 19 1 Forceps 0.5 Liter Ethyl Acetate, TOXI-LAB Grade 3 Disc-Handling Pins 50 TOXI GRAMS PLUS (11) Worksheets Reference Aids Accessories 1 TOXI-LAB AB Instruction Manual 1 Module I, Workstation / Storage Tray 1 TOXI-LAB Drug Compendium 1 Custom Electric Warmer 1 Heat Gun Services Basic Workshop TOXI-LAB® 67 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 68

DRG Drug Screening

TOXI-LAB AB-PLUS TOXI-LAB AB-PLUS Initial Systems (11-Channel TOXI GRAMS) TOXI-LAB AB-PLUS is the same product in principle as the TOXI-LAB System but uses larger (PLUS) chromatograms, allowing more samples to Supplies be tested per chromatograms, allowing more sam- 100 TOXI TUBES B ples to be tested per chromatogram. These 100 TOXI DISCAS Blank B systems are complete with hardware and supplies 50 TOXI DISCS B-1 for those laboratories who do not currently have 50 TOXI DISCS B-2 the TOXI-LAB AB System and require high volume 50 TOXI DISCS B-3 throughput. 50 TOXI DISCS B-4 Cat. No. TL400AB-11 6 Sets TOXI DIP B Reagent Concentrate (B-1, B-2, B-3) This system consists of the following: Cat. No. TL400A-11 TOXI LAB A-Plus Initial System Cat. No. TL420B-11 TOXI LAB A-Plus Conversion Pack

TOXI-LAB THC II TOXI-LAB THC II is a rapid thin-layer chromatographic method for marijuana metabolite, ∅9-THC-COOH, in urine. TOXI-LAB THC II may be used by hospital, reference, and forensic laboratories to screen or confirm the presence of ∅9-THC-COOH in urine ≥ 15 ng/mL. Contains supplies sufficient for 100 tests. Cat. No. TL261

Supplies Reference Aids 25 TOXI GRAMS Blank THC II (3-Channel) 1 TOXI-LAB THC II Instruction Manual 100 SPEC-C18-I Extraction Cartidges with with Color Detection Guides Sample Reservoirs 50 TOXI DISCS THC 500 Disposable Concentration Cups 2 Vials TOXI DIP THC-I Reagent Concentrate Services 2 30-mL Bottles of Hydrolysis Reagent Basic Workshop 1 50 mL Bottle of TOXI CONTROL THC 100 Worksheets, THC II (3-Channel)

Accessories 1 Custom Electric Warmer (not pictured) 1 Omega-12 Extraction Solvent Concentrator and Screen 2 Chromatography Jars with Caps 1 TOXI DIP Reagent Jar (THC-1) 1 HCI Standoff Jar with Cap 1 Small Standoff Jar with Cap (TOXI DIP THC-2 Reagent) 1 THC Developing Solution Bottle 1 Wash-Reagent-1 Bottle 1 Wash-Reagent-2 Bottle 1 Forceps 3 Disc-Handling Pins

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DRG Drug Screening

TOXI-LAB THC II-PLUS TOXI-LAB THC II-PLUS is an extension of TOXI-LAB THC II that employs larger chromatograms, TOXI GRAMS Blank THC II-PLUS (11), for simultaneous analysis of up to 10 speci- mens. Contains supplies sufficient for 200 tests. Cat. No. TL262 Supplies 50 TOXI GRAMS Blank THC II (11-Channel) 200 SPEC-C18-I Extraction Cartidges with Sample Reservoirs 50 TOXI DISCS THC 4 Vials TOXI DIP THC-I Reagent Concentrate 4 30-mL Bottles of Hydrolysis Reagent 1 50 mL Bottle of TOXI CONTROL THC 100 Worksheets, THC II (11-Channel)

Accessories Reference Aids 1 Custom Electric Warmer 1 TOXI-LAB THC II Instruction Manual Omega-12 Extraction Solvent Concentrator with Color Detection Guides 1 Chromatography Tank with Lid 1 Reagent Tank with Lid (for TOXI DIP THC-1 Reagent) 2 TOXI DIP Reagent Tanks with Lids and Services Standoffs (for TOXI DIP THC-2 Reagent Basic Workshop and HCI Reagent) 1 THC Developing Solution Bottle 1 Wash-Reagent-1 Bottle 1 Wash-Reagent-2 Bottle 1 Forceps

TOXI-LAB LTD Opiate The TOXI-LAB LTD Opiate Initial System is for low threshold detection (200 ng/mL) and differentiation of morphine, codeine, hydrocodone, hydromorphone, and dihydrocodeine. Cat. No. TL310

Supplies 20 TOXI GRAMS LTD Blank Opiate 20 TOXI DISCS LTD OP (Accessories cont ‘d) 20 TOXI DISCS LTD HD 1 Developing Solution I Bottle 20 TOXI DISCS LTD OPI 1 Developing Solution II Bottle 100 TOXI DISCS LDT Blank O 1 Wash Reagent Bottle 2 TOXI CONTROL LTD FM 1 Elution Reagent Bottle 100 SPEC LTD MP31 Columns 1 1M Acetic Acid Reagent Bottle 500 Disposable Concentration Cups 1 TOXI DIP A-2 Reagent Jar 100 LTD Opiate Devel. Sol. I Worksheets 1 TOXI DIP H2O Reagent Jar 100 LTD Opiate Devel. Sol II Worksheets 1 Forceps 3 Dis-Handling Pins Accessories 1 Module I (Workstation/Storage Tray) 1 Drummond Microdispenser Reference Aids 1 Custom Electric Warmer 1 LTD Opiate System Instruction Manual 1 Heat Gun and Color Detection Guides 1 Heat Gun Holder 1 Ammonium Hydroxide Vial with Cap 1 Omega-12 Extraction Solvent Concentrator and Screen Services 2 Chromatography Jars with Cap Basic Workshop

1) A vacuum system is required for use of this product (see page 67) TOXI-LAB® 69 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 70

DRG Drug Screening

TOXI-LAB A-PLUS Conversion Pack This product is for existing TOXI-LAB AB customers needing to expand the number of tests per analysis using TOXI-LAB A. Cat. No. TL420A-11

Supplies 50 TOXI GRAMS Blank A-PLUS 50 TOXI GRAMS PLUS Worksheets

Accessories 1 TOXI-LAB Chromatography Tank and Lid 1 TOXI DIP A-2 Reagent Tank and Lid 1 TOXI DIP H O Reagent Tank and Lid 2 Reference Aids 1 TOXI DIP A-3 Reagent Tank and Lid 3 TOXI DIP Chromatogram Stands 1 TOXI-LAB AB Instruction Manual 1 Large Standoff Jar

TOXI-LAB B-PLUS Conversion Pack This product is for existing TOXI-LAG AB customers needing to expand the number of tests per batch using TOXI-LAB B. Cat. No. TL420B-11

Supplies 50 TOXI GRAMS Blank B-PLUS (11) (500 tests) 50 TOXI GRAMS PLUS (11) Worksheets

Reference Aids 1 TOXI-LAB AB Instruction Manual

Accessories 1 TOXI-LAB Chromatography Tank and Lid 3 Stock Reagent Bottles (B-1, B-2, B-3) 1 TOXI DIP B-1 Reagent Tank and Lid 1 TOXI DIP B-2 Reagent Tank and Lid 1 TOXI DIP B-3 Reagent Tank and Lid 1 TOXI DIP Chromatogram Stand

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DRG Drug Screening

TOXI-LAB LTD Opiate Starter Pack Basic LTD Opiate Starter Pack supply package for laboratories who currently use the TOXI- LAB AB System. 100 tests/pk Cat. No. TL319

Supplies 20 TOXI GRAMS LTD Blank Opiate 20 TOXI DISCS LTD OP 20 TOXI DISCS LTD HD 20 TOXI DISCS LTD OPI 100 TOXI DISCS LDT Blank O 2 TOXI CONTROL LTD FM Reference Aids 100 SPEC LTD MP34 Columns 1 LTD Opiate System Instruction Manual 500 Disposable Concentration Cups and Color Detection Guides 100 LTD Opiate Devel. Sol. I Worksheets 100 LTD Opiate Devel. Sol II Worksheets 1 Developing Solution I bottle 1 Developing Solution II bottle 1 Wash Reagent bottle 1 Elution Reagent bottle 1 1M Acetic Acid Reagent bottle

A vacuum system is required for the extraction of ana- Solid Phase Extraction Vacuum System lytes where SPEC•Solid Phase Extraction columns are used. A581 TOXI•LAB THC II and LTD•Opiate systems employ This manifold allows simultaneous extraction of up to 12 sam- SPEC•columns. The following vacuum products and ples using the SPEC•Solid Phase Extraction columns. Precise equipment are efficient and effective for use in perfor- flow control is provided by simply rotating the independent, ming solid phase extractions. screw-type valves built into the cover, eliminating the need for separate stopcock valves.

The clear glass chamber allows observation of fluids as they pass Solid Phase Extraction Vacuum System through the SPEC•columns. The polypropylene collection-vessel A580 rack is adaptable for use with the aluminum TOXI•LAB Dispos- This system provides all the equipment required for processing able Concentration Cups (Cat. No. A152) or various collection SPEC•column extractions and includes the Solid Phase Extrac- tubes. A vacuum gauge is included with this unit. tion Vacuum Manifold (Cat. No. A581), 115V, 60Hz Vacuum Pump (Cat. No. A582), and Vacuum Trap Assembly (Cat. No. A584). Dimensions: Length, 8 1/4 in; Width, 4 1/2 in; Height, 7 1/2 in. See individual catalog numbers for details. Shipping weight: 8 lbs (approximate) Solid Phase Extraction Vacuum System A580i Identical to Cat. No. A580, but uses the 230V AC, 50 Hz Vacuum Pump (Cat. No. A583).

TL 580 Solid Phase Extraction Vacuum System

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DRG Drug Screening

PACKS TOXI-LAB® Cat. No. Product Description Unit

TL 102A-50 TOXI-PACK A 50 50 Tests/pack

TL 102B-50 TOXI-PACK B 50 50 Tests/pack

CHROMATOGRAMS TOXI-LAB® Cat. No. Product Description Unit

TL 106A TOXI-GRAMS A-100 100 Chromatograms/pack

TL 120A TOXI-GRAMS Blank A-100 100 Chromatograms/pack

TL 405 TOXI-GRAMS Blank A-PLUS (11) 50 Chromatograms/pack

TL 417 TOXI-GRAMS Blank A-PLUS (19) 50 Chromatograms/pack

TL106B-100 TOXI-GRAMS B-100 100 Chromatograms/pack

TL 120B-100 TOXI-GRAMS Blank B-100 100 Chromatograms/pack

TL 421 TOXI-GRAMS Blank B-PLUS (11) 50 Chromatograms/pack

TL 256 TOXI-GRAMS Blank THC II 25 Chromatograms/pack (3-Channel)

TL 255 TOXI-GRAMS Blank THC II-PLUS 50 Chromatograms/pack (11-Channel)

TL 209-100 TOXI-GRAMS Blank THC 100 Chromatograms/pack

TL 311-100 TOXI-GRAMS Blank LTD Opiate 100 Chromatograms/pack (6-Channel)

TL 312-20 TOXI-GRAMS LTD 20 Chromatograms/pkg (6 Channel)

EXTRACTION SUPPLIES TOXI-LAB® Cat. No. Product Description Unit

TL 109A-100 TOXI-TUBES A-100 100 Tubes/pack

TL 109B-100 TOXI-TUBES B-100 100 Tubes/pack

TL 251 SPEC-C18-I 100 /pack

TL 475 Hydrolysis Tubes 50 /pack

TL 210 THC Disposable Glass Tubes 50 Tubes/pack

TL 320 SPEC LTD MP-3 SPEC 100/pack

TL 475 Hydrolysis Tubes with Caps 50 /pack

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DRG Drug Screening

CHEMICALS TOXI-LAB® Cat. No. Product Description Unit

TL 111-A TOXI-DIP A-3 7,5 mL/vial

TL111-B TOXI-DIP B Reagent concentrate 3 vials/set

TL 203 Ethyl Acetate TOXI-LAB Grade 0,5 L

TL 208-I TOXI-DIP THC-I Reagent concentrate 2 vials

TL 207-4 Hydrolysis Reagent 30 mL/bottle

TL 207-I Extraction Tablets 40 Tablets/bottle

DISCS - BLANK TOXI-LAB® Cat. No. Product Description Unit

TL 108A-100 TOXI-DISCS Blank A 100 discs/vial

TL 108B-100 TOXI-DISCS Blank B 100 discs/vial

TL 315 TOXI-DISCS-LTD Blank 100 discs/vial

DISCS - STANDARD TOXI-LAB® Cat. No. Product Description Unit

TL 121 TOXI-DISCS A-1:Morphine, Codeine, Meperidine, Methadone, Propoxyphen 50 discs/vial

TL 122 TOXI-DISCS A-2: Pseudoephedrine, 50 discs/vial Methamphetamine, Amphetamine, Nicotine, Caffeine, Acetaminophen, Cocaine, Diazepam

TL 123 TOXI-DISCS A-3: Quinine, 50 discs/vial Trifluoperazine, Imipramine, Chlorpromazine, Triflupromazine, Trimeprazine, Phencyclidine

TL 124 TOXI-DISCS A-4: Strychnine, 50 discs/vial Nortryptyline, Doxepin, Amitriptyline, Meprobamate, Methaqualone

TL 125 TOXI-DISCS B-1: Phenobarbital, 50 discs/vial Phenytoin, Secobarbital

TL 126 TOXI-DISCS B-2: Aprobarbital, 50 discs/vial Pentobarbital, Glutethimide 50 discs/vial

TL 127 TOXI-DISCS B-3: Amobarbital, 50 discs/vial Ethinamate

TL 128 TOXI-DISCS B-4: Barbital, Butabarbital, 50 discs/vial Diazepam

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DISCS - STANDARD TOXI-LAB® Cat. No. Product Description Unit

TL 208-2 TOXI-DISCS THC: 8-THC-COOH 50 discs/vial TL 314-OP TOXI-DISCS LTD OP: Morphine, 20 discs/vial Hydromorphone, Codeine

TL 314-HD TOXI-DISCS LTD HD: Hydrocodon, 20 discs/vial Dihydrocodeine

TL324-OPI TOXI-DISCS LTD OPI: Morphine, Codeine, 20 discs/vial Dihydocodeine

TL 129 Special Standard TOXI-DISCS 1 Drugs/Disc 10 discs/vial TL 129 A Special Standard TOXI-DISCS 2 Drugs/Disc 10 discs/vial

DISCS - CUSTOM ORDER - OPIATE TOXI-LAB® Cat. No. Product Description Unit

TL 329 TOXI-DISCS LTD OPIATE SPECIAL STANDARD made with one or combination of: Codeine, Hydromorphone, Diacethylmorphine, Dihydrocodeine, 6-Monoacety Imorphine, Hydrocodone, Morphine 1 drug/disc 20 discs/vial TL 329 A TOXI-DISCS LTD OPIATE SPECIAL STANDARD 2 drugs/disc 20 discs/vial TL 329 B TOXI-DISCS LTD OPIATE SPECIAL STANDARD 3 drugs/disc 20 discs/vial TL 157 Heat Gun Ho

TOXI-DISCS - SPECIAL PROCEDURE STANDARD TOXI-LAB® Cat. No. Product Description Unit

TL 129SA Sympathomimetic Amines 50 Discs/vial

(Amphetamines)

TL 129LM Differentiation of Low-Migrating 50 Discs/vial

Stage IV Substances

TL 129MH Morphine and Hydromorphone: 50 Discs/vial

Differentiation

TL 129QQ Quinine and Quinidine; 50 Discs/vial

Differentiation

TL 129BH Benzodiazepines, Hydrolysis Procedures 50 Discs/vial

TL 129BE Benzoylecgonine 50 Discs/vial

TL 129OP Opiate 50 Discs/vial

TL 129RAVE MDMA, MDA, MDEA 50 discs/vial

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DRG Drug Screening

DISCS - CONTROLS TOXI-LAB® Cat. No. Product Description Unit

TL 170A TOXI-CONTROL No. 1 Negative urine 50 mL/vial

TL 170B TOXI-CONTROL No. 2 50 mL/vial

TL 170C TOXI-CONTROL No. 3 50 mL/vial

TL 170E TOXI-CONTROL No. 5 50 mL/vial

TL 191AB TOXI-CONTROL No. 19 50 mL/vial

TL 208-3 TOXI-CONTROL THC 50 mL/vial

TL 313-FM TOXI-CONTROL LTD 50 mL/vial

ACCESSORIES TOXI-LAB® Cat. No. Product Description Unit

TL 151 Module I: Storage Tray for sample each preparation. Includes multiple outlet and fluorescent light TL 154 Moule II: Module for drug detetction; each includes turnable and 8 friction bands TL 155 Module III: Ultraviolet light unit for each use with long-wave Ultraviolet Light (Cat. No. Tl 116). Does not include UV Light. TL 153 OMEGA-121: Extraction solvent each concentrator and screen for use with Custom Electric Warmer- Disposable Concentration Cups and Heat Gun; holds 12 cups TL 118 Custom Electric Warmer: Low-heat each source for solvent evaporation with protective sheet. 220V TL 152 Disposable Concentration Cups: 500 Cups/pack Disposable aluminium evaporation cups for use with OMEGA-12 or with the LTD OPIATE system; holds entire TOXI-TUBES solvent layer TL 156 Heat Gun each Dual-voltage (110 V and 220 V) TL 157 Heat Gun Holder each

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DRG Drug Screening

ACCESSORIES TOXI-LAB® Cat. No. Product Description Unit

TL 116-220 Ultraviolet Light: ULV-21 Black-Ray, each long-wave UV-Light 365-366 nm; for viewing TOXI-GRAMS in Module III

TL 237 UV Light Bulb: Replacement Light Bulb each TL 113 C TOXI-RACK 3 Set: Multiple development set rack for developing up to three TOXI-GRAMS simultaneously, includes Chromatography Jar with Cap TL 184 Forceps (custom stainless steel forceps each for handling TOXI-DISCS) TL 186 Discs-Handling Pins: Pearl-headed 3 pins/pack pins for handling TOXI-DISCS TL 416 TOXI-DIP Chromatogram Stand: each Polypropylene stand for use with TOXI-DIP reagent tank to hold and drain freshly dipped TOXI-GRAMS A-PLUS and B-PLUS TL 190 L Microdispenser each positive displacement pipet 0-50 µL

CONTAINERS AND CAPS TOXI-LAB® Cat. No. Product Description Unit

TL 112 Developing Solution Bottle: each 100-ml bottle for storing developing solution. For use with either TOXI-LAB A or TOXI-LAB B TL 119 Stock Bottle: 500 ml bottle for each storing TOXI-DIP stock solution. For use with TOXI-DIP A-3, TOXI-DIP B-1, TOXI-DIP B-2 or TOXI-DIP B-3 TL 113A Chromatography Jar with Cap: each 13.5 x 5-cm flat-bottom jar for development of TOXI-GRAMS. Can accomodate TOXI-RACK 3 TL 193 Large Stand-off/Desiccating Jar: each 21 x 17-cm jar for use with TOXI-LAB-Products; silica gel desiccant and stand-off included TL 115A TOXI-DIP A-1 Small Stand-off Jar: each 14 x 5.8-cm jar for use with TOXI-DIP A-1 (formaldehyde); includes cap with handle and stand-off

TL 114A2 Reagent for TOXI-DIP A-2 250 ml each

TL 114A3 Reagent for TOXI-DIP A-3 250 ml each

TL 114H2O Reagent for TOXI-DIP H2O 250 ml each TL 114B1 Reagent for TOXI-DIP B-1 250 ml each

TL 114B2 Reagent for TOXI-DIP B-2 250 ml each

TL 114 B3 Reagent for TOXI-DIP B-3 250 ml each TL 211 THC Developing Solution Bottle: each 100 ml-bottle for storing THC developing solution TL 215 Small Stand-off Jar THC-2: 14 x 5.8-cm each jar for use with TOXI-DIP THC-2 (diethylamine); stand-off included 76 TOXI-LAB® Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 77

DRG Drug Screening CONTAINERS AND CAPS TOXI-LAB® Cat.Cat. No. No. ProductProduct Description Description Unit

TL 213 TOXI-DIP THC-1 Reagent Jar each Opaque 250-ml jar for use with TOXI-DIP THC-1 reagent

TL 474 HCI Stand off Jar with cap. 14 x 5.8 cm each

TL 476 Chromatography Jar with cap. 8.3 x 5.2 cm each

TL 331 LTD Opiate IM Acetic Acid Reagent Bottle, 100 mLeach

TL 332 LTD Opiate Wash Reagent Bottle, 100 mL each

TL 333 LTD Opiate Elution Reagent Bottle, 100 mL each TL 334 LTD Opiate Developing Solution I, Bottle, 100 mL each TL 335 LTD Opiate Developing Solution II, Bottle, 100 mL each TL 260 700-ml Chromatography Tank with Lid both TL 408 1200 ml Chromatography tank for each development of TOXI-GRAMS A PLUS TL 258 700-ml tank: for use with all TOXI-DIP THC-2 or HCI vapor/reagents (Includes stand-off and lid) TL 259 700-ml tank (opaque) with lid: both for use with TOXI-DIP THC-1 TL 410 1200-ml tank: for use with TOXI-DIP A-2, each TOXI-DIP H2O, TOXI-DIP A-3, TOXI-DIP B-1, TOXI-DIP B-2, TOXI-DIP B-3 For use with TOXI-GRAMS A-Plus +B-Plus

REFERENCE AIDS TOXI-LAB® Cat. No. Product Description Unit

TL 181AB TOXI-LAB AB Instruction Manual each TL 181CD TOXI-LAB Instruction Manual CD each TL 252 TOXI-LAB THC II Instruction Manual each and Detection Guide

TL 458 TOXI-LAB Alcohol Procedure Instruction Manual each TL 316 TOXI-LAB LTD OPIATE each System Instruction Manual TL 182A Color Detection Guide A: each Color photograph showing TOXI-GRAMS A drug standards in four detection stages TL 182B Color Detection Guide B: Color each photograph showing TOXI-GRAMS B drug standards in two detection stages TL 187-A TOXI-LAB A Worksheets: Worksheets pad depicting TOXI-GRAMS detection stages and standards (100 sheets/pad) TL 187-B TOXI-LAB B Worksheets: Worksheets pad depicting TOXI-GRAMS detection stages and standards (100 sheets/pad) TL 424 TOXI-GRAMS PLUS (11) Worksheets: pad Worksheets for recording observations of detected TOXI-GRAMS PLUS (50 sheets/pad) TL 425 TOXI-GRAMS PLUS (19) Worksheets: pad Worksheets for recording observations of detected TOXI-GRAMS PLUS

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DRG Drug Screening REFERENCE AIDS TOXI-LAB® Cat. No. Product Description Unit

TL 253 THC II Worksheets (3-Channel): pad Worksheets for recording observations of detected TOXI-GRAMS THC II (50 sheets/pad) TL 316 LTD Opiate Instruction Manual each and Detection Guides

TL 317 LTD Opiate Detection Guide each TL 254 THC II-PLUS Worksheets pad (11-Channel): Worksheets for recording observations of detected TOXI-GRAMS THC II (50 sheets/pad) TL 321 TOXI-LAB LTD OPIATE Developing pad Solution I Worksheet: Worksheet for recording observations with the TOXI-LAB LTD Opiate System TL 322 TOXI-LAB LTD OPIATE Developing pad Solution II Worksheet: Worksheet for recording observations with the TOXI-LAB LTD Opiate System TL 201 TOXI-LAB Drug Compendium each (Contains Color Detection Guides A and B), presented in Rolodex V-File TL 2011 TOXI-LAB Drug Compendium, each Intenational Edition (3-ring binder)

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Extraction - Solid Phase Extraction (SPEC) SPEC®

3 and 10 ml Columns

Integrated in a Pipette Tip

96 Well Formate

SPEC• Disc Technology SPEC solid phase extraction disc technology has revolutionized laboratory sample preparation procedures by providing the ana- lyst with an efficient, clean alternative to packed bed SPE products. SPEC discs consist of a glass fiber supporting matrix in which silica and bonded silica particles are embeded. The resulting rigid disc can be considered as an array of interconnected, closely- packed porous particles of small diameter.

SPEC disc technology has the following proven advantages over packed bed SPE:

Reproducibility Recovery Lot-to-lot Selective analyte retention Within-lot Eliminates channeling

Cleanliness More Efficient Processing No frit to contaminate the sample Fewer steps Retention: High analyte Faster throughput (high surface-to-volume ratio) Low nonspecific (interferences) Reduced solvent usage

Numerous technical publications are available that provide in-depth analysis of the above advantages. Please request the SPEC Bibliography for a list of the latest publications.

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Extraction - Solid Phase Extraction (SPEC)

For a 15-mg disc, the total capacity is up to 1.5 mg. SPEC• Disc Capacity For a 35-mg disc (10-mL columns) the total capacity is up SPEC’s efficient analyte retention means that a single 15-mg to 3.5 mg. If additional capacity is required, SPEC 3-mL and disc has sufficient capacity for most applications. We recom- 15-mL columns are available with a 30-mg bed mass. Larger mend using a 15-mg mass to develop applications that take SPEC discs (47- and 90-mm diameter) may be used for larger maximum advantage of SPEC’s low bed mass disc technology. sample volumes (generally greater than 100 mL) such as envi- The 15-mg disc is available in 3-mL columns, 15-mL columns, ronmental samples and for drug metabolism studies. an 96-well plates. Typical capacity of a SPEC disc is 5-10% of The 4-mg disc in the pipette tip, with capacity up to 0.4 mg, is the bed mass. ideal for small sample volumes. SPEC•PLUS Processing plasma and other particulate-laden matrices has system in addition to the SPEC extraction disc to allow rapid proven to be a formidable task for SPE technology. SPEC•PLUS processing of biological samples and other complex matrices. was specifically designed for difficult samples of this type. This fast-flowing filter design prevents clogging, even without SPEC•PLUS products incorporate a special glass fiber filter sample centrifugation or off -line filtration.

How to choose the correct

bonded phase mal phase should minimize interferences without affecting The bonded phase chosen for your extraction should maximize analyte recovery. The more specific the interaction between selectivity for the analyte of interest and minimize affinity for the analyte and the bonded phase, the cleaner the final extract. interfering substances. Retention depends on the interaction between the functional groups of the analyte and those of a Fifteen sorbent materials are currently available. The broad particular bonded phase. range of chemistries allows optimized selectivity for the Separation of matrix interferences from the analyte is optimi- analyte of interest. SPEC’s proprietary disc technology and zed by focusing on the differences in their chemical nature. attention to product quality assure excellent lot-to-lot and While several bonded phases may retain the analyte, the opti- within-lot reproducibility.

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Extraction - Solid Phase Extraction (SPEC)

Product Cat No. Quantity mg bed mass Volume

SPEC PLUS C2 502-01-35 100 pcs/pck 35 10 ml SPEC PLUS C8 502-02-35 100 pcs/pck 35 10 ml SPEC PLUS C18 502-03-35 100 pcs/pck 35 10 ml SPEC PLUS SCX 502-04-35 100 pcs/pck 35 10 ml SPEC PLUS SAX 502-05-35 100 pcs/pck 35 10 ml SPEC PLUS CN 502-06-35 100 pcs/pck 35 10 ml SPEC PLUS NH2 502-07-35 100 pcs/pck 35 10 ml SPEC PLUS SI 502-08-35 100 pcs/pck 35 10 ml SPEC PLUS PH 502-10-35 100 pcs/pck 35 10 ml SPEC PLUS MP1 502-11-35 100 pcs/pck 35 10 ml SPEC PLUS PSA 502-16-35 100 pcs/pck 35 10 ml SPEC PLUS C18AR 502-19-35 100 pcs/pck 35 10 ml SPEC PLUS MP3 502-20-35 100 pcs/pck 35 10 ml SPEC PLUS C18AR/MP3 502-25-70 100 pcs/pck 70 10 ml SPEC C18 531-03-20 100 pcs/pck 15 3 ml SPEC C18 531-03-30 100 pcs/pck 30 3 ml SPEC SCX 531-04-20 100 pcs/pck 15 3 ml SPEC SCX 531-04-30 100 pcs/pck 30 3 ml SPEC MP1 531-11-20 100 pcs/pck 15 3 ml SPEC MP1 531-11-30 100 pcs/pck 30 3 ml SPEC C18AR 531-19-20 100 pcs/pck 15 3 ml SPEC C18AR 531-19-30 100 pcs/pck 30 3 ml SPEC MP3 531-20-20 100 pcs/pck 15 3 ml SPEC MP3 531-20-30 100 pcs/pck 30 3 ml SPEC C18AR/MP3 531-25-30 100 pcs/pck 30 3 ml SPEC PLUS C2 532-01-20 100 pcs/pck 15 3 ml SPEC PLUS C2 532-01-30 100 pcs/pck 30 3 ml SPEC PLUS C8 532-02-20 100 pcs/pck 15 3 ml SPEC PLUS C8 532-02-30 100 pcs/pck 30 3 ml SPEC PLUS C18 532-03-20 100 pcs/pck 15 3 ml SPEC PLUS C18 532-03-30 100 pcs/pck 30 3 ml SPEC PLUS SCX 532-04-20 100 pcs/pck 15 3 ml SPEC PLUS SCX 532-04-30 100 pcs/pck 30 3 ml SPEC PLUS SAX 532-05-20 100 pcs/pck 15 3 ml SPEC PLUS SAX 532-05-30 100 pcs/pck 30 3 ml SPEC PLUS CN 532-06-20 100 pcs/pck 15 3 ml SPEC PLUS CN 532-06-30 100 pcs/pck 30 3 ml SPEC PLUS NH2 532-07-20 100 pcs/pck 15 3 ml SPEC PLUS NH2 532-07-30 100 pcs/pck 30 3 ml

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Extraction - Solid Phase Extraction (SPEC)

Product Cat No. Quantity mg bed mass Volume

SPEC PLUS SI 532-08-20 100 pcs/pck 15 3 ml SPEC PLUS SI 532-08-30 100 pcs/pck 30 3 ml SPEC PLUS PH 532-10-20 100 pcs/pck 15 3 ml SPEC PLUS PH 532-10-30 100 pcs/pck 30 3 ml SPEC PLUS MP1 532-11-20 100 pcs/pck 15 3 ml SPEC PLUS MP1 532-11-30 100 pcs/pck 30 3 ml SPEC PLUS PSA 532-16-20 100 pcs/pck 15 3 ml SPEC PLUS PSA 532-16-30 100 pcs/pck 30 3 ml SPEC PLUS C18AR 532-19-20 100 pcs/pck 15 3 ml SPEC PLUS C18AR 532-19-30 100 pcs/pck 30 3 ml SPEC PLUS MP3 532-20-20 100 pcs/pck 15 3 ml SPEC PLUS MP3 532-20-30 100 pcs/pck 30 3 ml SPEC PLUS C18AR/MP3 532-25-30 100 pcs/pck 30 3 ml SPEC PLUS DAS 532-DAS 100 pcs/pck 3 ml SPEC PLUS DAU 532-DAU 100 pcs/pck 15 3 ml

Pipettenspitzen/Pipettetips SPEC PT C18 572-03 96 pcs/pck SPEC PLUS C18AR 572-19 96 pcs/pck

96-Well-Plate Format SPEC C18 596-03 1 Plate 96-well-plate SPEC PLUS C18AR 596-19 1 Plate 96-well-plate SPEC PLUS Development 596-30 1 Plate 96-well-plate

Accessories: TL 580 Solid Phase Extraction Vacuum System Incl. Manifold for 12 Columns, Vacuum Pump, Trab Assembly

TL 581 Solid Phase Extraction Vacuum Manifold for 12 Columns TL 583 Vacuum Pump (20 in Hg) TL 584 Vacuum Trap Assembly RIK BA-1 Buffer A (1% Trifluoroacetic acid) 500 ml RIK BB-1 Buffer B (60% Acetonitril in 1% Trifluoroacetic Acid) 100 ml

TL 580 Solid Phase Extraction Vacuum System

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Extraction - Liquid/Liquid EXTRACTION SUPPLIES Cat. No. Product Description Uni

TL 109A TOXI-TUBES A-100 100 Tubes/pack Ready to use liquid/liquid extraction tubes for basic and neutral drugs TL 109B TOXI-TUBES B-100 100 Tubes/pack Ready to use liquid/liquid extraction tubes for acidic and neutral drugs

TOXI-Tubes A

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Index (Immunoassays, Rapid Screen Tests) Acetylcholin-Rec. Auto-Ab 13, 32 C1q 32 ACPA 13 C3bi 32 ACTH 11, 31 C3d 32 Adenovirus 47 C5a 33 Adipocyte FABP 13 CA 15-3 10, 45 Adiponectin 17 CA 19-9 10, 45 ADM 1-50 42 CA 72-4 10, 16, 45 Pro-ADM 45-92 42 CA 125 10, 45 Pro-ADM 153-185 42 CA 242 45 Adrenalin (Epinephrine) 23 CagA Assay 49 Adrenalin 23 Calcitonin 39 Adrenomedullin 42 Calcitonin Gene Rel. Peptide (CGRP) 31 ADV (Aujeszky’s Disease) 62 Calcitonin Gene Related Peptide II 31 Afamin 35 Calprotectin 17 AFP 10, 27, 45 Candida albicans 47 Aggrecan PG 32 Carbonylprotein 13, 24 Agouti-related Protein (83-132) 42 Anti-Cardiolipin 13 Akt (Total) 32 Anti-Cardiolipin Screen 13 Akt [pS473] 32 Caspase 32 Aldosterone 9, 16, 31, 37 Cat Combi (Adrenalin/Noradrenalin) 23, 24 Aldosterone ELISA 37 Anti-Cathepsin G 13 Anti-Alpha-Fodrin 13 CAV (Canine Adeno Virus) 60 Alpha-1 Microglobulin 23 Cartilage Oliomeric Matrix Protein 13 Alpha Subunit 45 CBG (Transcortin) 31 AMA-M2 13 CCK (Cholecystokinin) (26-33) 17, 18 AMH (anti-Mullerian Hormone) 27 anti-CCP 2 13 cAMP 39 CCV (Canine Corona Virus) 61 Amphetamine 22 sCD 14 33 Amphetamine Schnelltest 63 sCD 23 33 Amylase 17 sCD 30 33 Amylin 17 sCD 40 33 Amyloid Beta 1-40/1-42 23, 42 CDV (Canine Distemper Virus) 60 Amyloid Beta 13, 23, 42 CEA 10, 45 ANA Combi 13 Anti-Centromer B 13 ANA Detect 13 CETP 23 ANA Screen 13 anti-Centromer B 13 ANCA Combi 13 CH50 42 ANCA Screen 13 Chagas 47 Anti-PR-3 (c-ANCA) 13 Chikungunya 47 Anti-MPO (p-ANCA) 13 Chlamydia Antigen Schnelltest 63 Androstandiol Glucuronide 9, 16, 27 Chlamydia pneumoniae 48 Androstenedione 10, 27, 44 Chlamydia trachomatis 48 ANF 23 Chromoglycate 22 Prepro-ANF 23 Chromogranin A 45 Angiotensin I 23 CHV (Canine Herpes Virus) 60 Angiotensin II 23 CK-MB 24, 37 Anti-Annexin V 13 Clostridium 48 ANP 23, 37 CMV 48 Alpha-ANP 1-28 23, 37 Cocaine Schnelltest 63 ß ANP 23, 37 Complement C3a des Arg 32 Apo A 37 Complement C4a des Arg 32 ARAb RRA (Acetylchol. Rec. Ab) 32 Controls 59 ASCA 13 Corticosterone 31 Ascaris lumbricoides 47 Corticotropin Releas. Factor 31 anti-ASGPR 13 Cortisol 11, 16, 31 Aspergillus fumigatus 47 11-Desoxycortisol 31 Astrovirus 47 Corynebacterium 48 Avian Leukosis Virus-p27 47 Cortistatin-29 18 Barbiturate Schnelltest 63 Cotinin 22, 44 Bax 45 COX-II 41 BCL2 45 Coxiella 48 ßDNF 42 Coxsackievirus 48 Benzodiazepine Schnelltest 63 C-Peptide 10, 17 Biotin Bio-Assay 52 CPV (Canine Parvo Virus) 60 BLV (Bovine Leukemia Virus) 61 Cripto-1 45 Brain Natr. Pept. (BNP 32) 24, 37 CRP (C-reactive Protein) 24, 48 BNP-32 (Rat) 24, 37 Cryptosporidium antigen 48 BNP-45 (Rat) 24, 37 CTGF 24 Prepro BNP 22-46 24, 37 C-Type Natr. Pept. 22 24 Bombesin 17 CYFRA 21-1 10, 16, 45 Bordetella pertussis/toxin 47 Cyclosporin 33 Borrelia burgdorferi „LYME“ 47 CYR-61 24, 37, 45 Anti-BPI 13 Cystatin C 24, 37 BRCA-1 45 Cytochrome C 33 Brucella (Human) 47 DAO 18 Brucella Ab (Bovine) 61 Dengue 48 Buprenorphine 22 Deoxypyridinoline 39 DHEA 10, 27 84 Index Preisliste aktuell 10.2011_B+F_Preisl. 2006_04 o.Preis_drg 07.11.11 09:57 Seite 85

Index (Immunoassays, Rapid Screen Tests) DHEA Sulfate (DHEA-S) 16, 27, 44 Galactose neon. (exc. Membrane Plate) 24 DHEA-S Saliva 44 Galanin 42 Diabetes Antigen Control 18, 59 Galectin 3 (Human) ELISA 33 Diphteria (antitoxin) 48 Gastrin 18, 31 Anti-dsDNA 13 Big Gastrin 18 Anti-dsDNA Screen 13 Gastro Screen Blot 14 Anti-ssDNA 13 Gastrin Releasing Peptide 18 Disposables 58 Anti-GBM 14 Dopamin 24 GCSF 33 6 ff hGH 24 DR 4 33 GH 24 Drug Screen Pro 5 Schnelltests 63 Ghrelin 18 Dynorphin A (1-8) 42 Ghrelin, Prepro- 18 Dynorphin A (Porcine) 42 Giardia lamblia antigen 48 Echinococcus 48 GIP (Gastr. Inhibit. Pept.) 18 Echovirus 48 Gliadin 14 E.coli 48 Glicentin 18 hEGF 53 GLP 1, GLP 2 18 Elastase-1 14 Glucagone 18 Anti-Elastase 14 Glucagone like Peptide 1 18 E-LizaMat 3000/2000/8882/8884 54 ff Glucagone like Peptide 2 18 ENA Combi 14 3 alpha DIOL Glucoronide 27 ENA Profile 8 14 Glycodelin (PP14) 28 ENA Screen 14 Anti Beta2 Glycoprotein 1 14 ENA-4-Profile 14 Glycopyrrolate 22 ENA-6-Profile 14 GM-CSF 33 ENA-8-Profile 14 cGMP 39 ß-Endorphin 42 Gonorrhea Schnelltest 63 Endostatin 18, 33 GRO/CINC-1 (Cytokine ind. Neutrophile) 33 Endothelin 24, 37 GRO/CINC-3 33 Big Endothelin 24, 37 Growth Hormone RF 31 Endothelin-1 24, 37 GSTA 24 Endothelin-2 24, 37 HAMA 33 Endothelin-3 24, 37 Hantavirus 48 Prepro-Endothelin (18-50) 24 Haemophilus 48 Prepro-Endothelin (94-109) 24 HAV (antibody) 48 Entamoeba histolytica 48 HBc 49 Eppendorf Pipetten 58 HBe 49 Epstein Barr Virus (EA) 48 HBs Ag 49 Epstein Barr Virus (EBNA) 48 HBs Ag Schnelltest 63 Epstein Barr Virus (VCA) 48 HCG 28, 46 Epstein Barr Virus (VCA) IgM Capture 48 HCG Schnelltest 63 ER 60 ELISA 27 ßHCG/HCG 28, 46 Erythropoietin 33 Free ßHCG 28, 46 Estradiol 16, 27, 44 HCV 49 Total Estriol 28 HCV Schnelltest 63 Free Estriol 16, 28, 44 HDV 49 Estrogen Total (E1+E2) 28 hEGF 53 Estrone 16, 28, 44 Helicobacter Pylori IgA 49 Estrone Sulphate 28 Helicobacter Pylori IgM 49 FABP 23 Helicobacter Pylori IgG 49 Fasciola (Hepatica) 48 Helicobacter Pylori (stool) 49 FAS (Apo-1/FAS/CD95) 33, 35 Helicobacter Pylori Combo Schnelltest 63 FCV (Feline Calici Virus) 60 HepAK DOT 14 FeLV-gp70 (Feline Leukemia Virus) 60 Hepcidin 25 Fentanil 22 Hepcidin Prohormone 24, 39 Ferritin 39, 46 sp185 (HER-2) 46 Fertility Control 53 Herpes Simplex 1 16, 50 Festphasenextraktion SPEC 79 ff Herpes Simplex 1+2 50 Fetuin A 37, 39 Herpes Simplex 2 50 FGF-19 24 12-Hete 41 FGF-23 39 15-Hete 41 FHV (Feline Herpes Virus) 60 HEV 49 Fibronectin 33 HGH 53 FIPV (Feline Infectious Peritonitis) 60 HGF (Hepatocyte Growth Factor) 53 FIV (Feline Immunodefency Virus) 60 HGV 49 Flavivirus (West Nile) 48 5-HIAA 33 FPV (Feline Parvo Virus) 60 Histamin 33 Free ßHCG 28, 46 Anti-Histone 44 Free Testosterone 16, 29 HIV 50 Folic Acid 52 HMg BI 33 FSH 28 HNP 1-3 41 FSME „Tickborne encephalitis virus“ 48 Homocysteine 25, 37 Anti-GAD 14, 18 HPL 28 Anti-GAD65 RLA 14, 18 HPV IgG 50 Hsp 60 33 Hsp70 33

Index 85 Preisliste aktuell 10.2011_B+F_Preisl. 2006_04 o.Preis_drg 07.11.11 10:04 Seite 86

Index (Immunoassays, Rapid Screen Tests) HTLV I/II Screening 33, 50 Lp (a) 25, 37 HVA 33 Lyme Borrelia 50 6 ff anti-Lysozyme 14 21 Hydroxilase Ab 14 Malaria 50, 63 Anti-IA2 14, 19 Marijuana Schnelltest 63 IAA 19 MCH 42 HGH 24 MCP 1 35 IBR Blocking Bovine antibodies 62 Measles 50 ICA (Isle-Cell Autoantibody) 14, 19 Melatonin 44 ICA II 14, 19 Melatonin Sulfate 25 ICAM-1 25 Meningitis 50 IEN alpha 33 Metamphetamines 22 IgA Saliva 44 Metamphetamines Schnelltest 63 IgA-CIC 33 Metanephrine 25 IgE-CIC 33 MetCombi (Metanephrine/Normetan.) 25 IgG-CIC 33 Methadone Schnelltest 63 IgM-CIC 33 Methylphenidate 22 IGF BP-1 28 Microalbumin 20 IGF BP-2 53 Micro Celite Columns 58 IGF BP-3 53 Alpha-1 Microglobulin 23 IGF BP-6 53 ß2-Microglobulin 46 IGF-1 600 53 anti-ß2-Microglobulin 1 14 IGF-2 53 Microtiterplate Washer 54 Immunoassay Control Sera 59 Microtiterplate Reader 54 INF gamma 33 Microtiterplate Shaker/Incubator 54 Influenza A 50, 63 MIP-1ß 35 Influenza H1N1 63 MIP-2 35 Influenza B 50, 63 MIP-5 35 Inhibin alpha 1-32 28 MMP-9 35 Insulin 19 MMP-13 35 anti-Insulin Ab 14 Morphine 22 Interferon alpha 33 anti-MPO 25 Interferon gamma 33 alpha-MSH 42 Interferon ß 33 beta-MSH 42 Interleukin-1 a 34 gamma-MSH 42 Interleukin-1 ß 34 Multipette 58 Interleukin-2 34 Mumps 50 Interleukin-2 Receptor 34 Mycoplasma hominis 50 Interleukin-4 34 Mycoplasma Pneumoniae 50 Interleukin-5 34 Myelin Basic Protein (MBP) 25 Interleukin-6 34 Myoglobin 25, 38 Interleukin-8 34 Myoglobin Schnelltest 63 Interleukin-10 34 Myositis Screen Blot 14, 15 Interleukin-12 34 Neopterin 35 Interleukin-13 34 Neurokinin A 42 Interleukin-15 34 Neurokinin B 42 Interleukin-17 35 Neuropeptide Y 42 Interleukin-18 35 Niacin 52 Interleukin-20 35 Noradrenalin (Norepinephrine) 25 Interleukin-23 35 Normetanephrine 25, 26 Intrinsic Factor 14 Norovirus 26 Involucrin 35 NOV 26 IP10 35 NSE 46 JE (Japanese Encephalitis) 50 Nucleo Screen Blot 15 anti-Jo-1 14 anti-Nucleosomes (SLE) 15 Kathepsin D 36 Occult Detect 64 Kontrollen 59 OPG 39 Kontrollurine 59 Opiates 22 L-1 CAM 46 Opiate Schnelltest 63 Lactate Saliva 25, 44 Orexin A 20 anti-Lactoferrin 14 Orexin B 20 anti-LC1 14 Orphanin FQ (Nociceptin)* 42 LDL 37 Osteocalcin 39, 46 Legionella 50 Osteopontin 39 Leishmania 50 Osteoprotegerin 39 Leptin 19, 20 Oxytocin 26 Leptospira IGM 50 Ovarian Antibodies, Anti- 15, 29 Leptospira Grippothyphosa 50 Ovary Ab Latex 29 Leptospira Hardjo Bovine 62 P27 46 Leukotriene B4 41 P53 46 Leumorphin 42 t-PA 26 LH 28 PACAP 27-NH2 42 LH Schnelltest 63 PACAP 38 42 LH Releasing Hormone 31 Pancreatic Peptide 20 LIF-HILDA 35 P2 ANP (C-type 2 Collagen) 20 Lipase 20 Pancreatic Polypeptide 20 Liver Screen Blot 14 Pankreastatin 20 anti-LKM-1 14 Pankrin 20 Panthothenic acid 52 86 Index Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 87

Index (Immunoassays, Rapid Screen Tests) PAP 46 anti-SS-B (La) 15 PAP (Plasmin a2-antiplasmin complex) 35 Stongyloides 51 PAPP-A (Pregnancy Associatied Plasma Protein) 29 Substance P 21, 42 PAPP-A (ultrasensitive) 29, 38 Survivin 46 Parainfluenza 1/2/3 50 Syphilis (Treponema) 51 anti-Parietal Cell 15 Syphilis Schnelltest 64 Parvovirus B19 50 T3 10, 43 PCP Schnelltest 64 T3, free 10, 43 Pepsinogen 20 T4 10, 43 Peptide YY (PYY) 20, 42 T4, free 10, 16 43 Phenylalanin Neonate 26 T4 (Cat) 43 PHM-27 (PHI) 20 T4 (Dog) 43 anti-Phosphatidic Acid 15 Taenia solium (Cysticercosis) 51 anti-Phosphatidyl Inositol 15 TAFI 36 Phosphatidylserin Ab 15 TAU total 26 Phospholipid Antibodies, Anti- 15 TB Rapid Screen 64 Pipetten 58 Testosterone 16, 29, 30, 44 Pipette Tips 58 Testosterone, Dihydro- 30 PKU 26 Testosterone, Free 16 PLGF 10, 29 Testosterone, 11-keto 29, 30 PMN Elastase 35 Tetanus IgG 51 PMSG (Pregnant Mare Serum Gonadotropin) 62 TG Ab (Thyroglobulin Ab) 10, 15 P-111-P (Procollagen 111 Peptide) 20 TGF-1 (rat) 53 anti-Prothrombin 15 Pregnenolone H-3 29 TGF ß1 36, 53 Pregnenolone, 17 a-Hydroxy-, H-3 29 TGF ß2 36, 53 Progesterone 10, 16, 29, 44 Thrombo-Combo 15 Progesterone, 17 a-Hydroxy- 10, 16, 28, 44 Thromboxane B2 38, 41 Progesterone, 17 a-Hydroxy-, Neonate 28 Thyroglobulin Ab (TG Ab) 15, 43 Proinsulin 20 Thyroglobulin Ag 10, 43 Prolactin 10, 16, 29 Thyroid Control Sera 59 Prostacyclin 41 Thyroid Peroxidase Ab (TPO Ab) 10, 43 Prostaglandin E1 41 Thyvoid Fever 58 Prostaglandin E2 41 TNF a 36 Prostaglandin F2a 41 TNF Beta 36 Prostaglandin, 6-Keto-, F1a 41 TOXI•LAB® 65 ff Prostaglandin 8-iso, F2a 41 TOXI Tubes A, B 66 Prostaglandin 9a, 11b, F2a 41 Toxocara canis 51 Prostaglandin 15-deoxy-delta12, 14, J2 41 Toxoplasma gondii 16, 51 Protein A 35 t-PA 26 PSA free 10, 46 TPA 10, 46 PSA 10, 16, 46 TPO Ab (Thyroid Microsomal Ab) 15 PSA Schnelltest 64 TPS (Cyk 18) 10, 46 PTH 1-34 40 TRAIL 36 PTH 1-38 40 Transcortin (CBG) 31 PTH 1-44 40 Transferrin Receptor 36 PTH intact 39 Transglutaminase 15 PYY 20 Treponema 51 Rabies 62 TriCat (Adreanlin/Noradrenalin/Dopamin) 23 sRankl 35 Trichinella IgG 51 Relaxin 26 Tricyclics 22 Renin 10, 26, 31, 38 Troponin 26, 28 Resistin 20 Troponin Schnelltest 64 Retinol Binding Protein 26 Trypanosoma cruzi 51 RF (Rheumatoid Factor) 15 Trypsin Neonate 26 RIA Control Sera 59 TSH 10, 16, 43 Ribosomal P Ab 15 TSH Neonate 43 Rickettsia 51 TSH Receptor 15, 43 Ritips 58 Tuberculosis 51, 64 RLMB 26 anti-RNP/Sm 15 Tumor Marker Control (Sera) 46 anti-RNP/70 Kd 15 T-Uptake 43 Rotavirus 51 UBC (Urinary Bladder Cancer) 46 RSV 51 UBC Schnelltest 64 Rubella 16, 51 Ureaplasma 51 S100A8/S100A9 15 Urocortin 21 S100B 46 Urodilatin 21 SCC 46 Urotensin 11 31 SCD 44 46 Vacuum Manifold (including vacuum pump) 71 Sali Tubes 44 Varicella zoster 51 Saliva Control 29 Vasopressin 26 Salivary Diagnostics 10, 44 VCAM-1 26, 36 Sarafotoxin SG6 47 VDBP 26 Schistosoma (Billharziosis) 51 VEGF (Vasc. Endoth. Gr. Fact.) 36, 53 anti-Scl-70 15 Veterinary Diagnostics 60 ff Secretin 20 VIP (Human, Rat, Porcine) 21 Secretory 15 Vitamines 52 Selectin 35 Vit. B 12/ Folic Acid 40, 52 Serotonin 26 Vit. D, 1.25 Dihydroxy- 40, 52 SHBG 10, 29 Vit. D, 25 (OH) 10, 40, 52 SHLA-6 35 Vitamin D Binding Protein 26 anti-Sm 15 Vitamin C 52 Somatostatin - 28 20 Vitamin D Total 40 Somatostatin 20 VMA 22, 26, 28 SPEC Solid Phase Extraction 79 ff West Nile Virus 51 Sperm Antibody 15, 29 Yersinia enterolitica 51 anti-SS-A (Ro) 15 Zeta Globulin 26 anti-SS-A 52 15 Zona Pellucida Ab 30 anti-SS-A 60 15 Index 87 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 88

Allgemeine Geschäftsbedingungen

1 Umgangsgenehmigung 6 Eigentumsvorbehalt Radioaktive Reagenzien dürfen nur an Personen geliefert wer- Die gelieferte Ware bleibt unser Eigentum bis zur vollen Bezah- den, die im Besitz einer von der zuständigen Behörde ausge- lung. Sicherungsübereignung und Sicherungsverkauf oder Ver- stellten Umgangsgenehmigung sind (Str.SchV vom 30.06.89). pfändung der unter Eigentumsvorbehalt stehenden Ware ist unzulässig. Durch Übernahme von Forderungen in eine laufen- de Rechnung durch Sanierung und Anerkennung des Saldos wird der vereinbarte Eigentumsvorbehalt nicht berührt. 2 Aufträge Mit der Erteilung eines Auftrages erkennt der Kunde unsere all- gemeinen Verkaufsbedingungen an. Abweichende Vereinbarungen bedürfen unserer schriftlichen Bestätigung. 7 Mängelrügen Mängelrügen hat der Käufer spätestens eine Woche nach Empfang der Ware schriftlich zu erheben. Maßgeblich ist der Zeitpunkt des Eingangs der Rüge. Mangelhafte Ware ist zur 3 Preise Verfügung zu stellen, eine Rücksendung bedarf aber grundsätz- Die Listenpreise sind freibleibend und gelten nur für den lich unserer schriftlichen Einverständniserklärung. Inlandsbedarf. Die Berechnung erfolgt stets zu den am Tage der Lieferung gültigen Preisen. Die Mehrwertsteuer ist in den ange- gebenen Preisen nicht enthalten, sie wird zu dem jeweils gelten- den Prozentsatz zusätzlich in Rechnung gestellt. Die Fracht- und 8 Erfüllungsort Verpackungskosten für Inlandslieferungen betragen EURO 12,00 Erfüllungsort ist Marburg/Lahn. für Express-Lieferungen EURO 22,00 und für Radioaktive Sendungen EURO 22,00, gültig ab 1. Mai 2010.

9 Gerichtsstand Gerichtsstand, auch für Wechsel und Scheckeinlagen, 4 Lieferung ist Marburg/Lahn. Sämtliche Sendungen erfolgen auf Gefahr des Käufers. Wir selbst übernehmen keine Verantwortung für Bruch und daraus entstehende Folgen und lehnen Ersatzansprüche ab. Von der Verpflichtung der Lieferung sind wir befreit, wenn uns 10 Verbindlichkeiten durch Umstände, die zu beseitigen nicht in unserer Macht liegt, Durch Erteilung des Auftrages erklärt der Käufer sein Einver- die Lieferung unmöglich macht oder in nicht tragbarer Weise ständnis mit vorstehenden Verkaufsbedingungen. Abweichende erschwert wird. Im Falle begründeter Reklamationen jeglicher Bedingungen des Käufers und mündliche Vereinbarungen sind Art, die im Zusammenhang mit unseren Lieferungen stehen, für uns nur verbindlich, wenn sie von uns ausdrücklich schrift- behalten wir uns vor, den daraus entstandenen Anspruch durch lich bestätigt werden. Die etwaige rechtliche Unwirksamkeit Lieferung mangelfreier Ersatzware oder durch Gutschrift zu eines Teils dieser Verkaufsbedingungen ist auf die Gültigkeit des regulieren. sonstigen Inhalts derselben ohne Einfluß. Weitergehende Ansprüche wegen Nichtlieferung oder nicht rechtzeitiger Lieferung sowie aus jedem anderen tatsächlichen oder rechtlichen Grund sind soweit gesetzlich zulässig, ausge- schlossen.

5 Zahlung Unsere Rechnungen sind zahlbar innerhalb 30 Tagen ohne Abzug oder innerhalb von 10 Tagen nach Rechnungsdatum mit 2 % Skonto. Bei Fristüberschreitung werden Verzugszinsen in Höhe von 2 % über dem offiziellen Diskontsatz berechnet. Eine Zahlung gilt erst dann als geleistet, wenn wir über den Betrag verfügen kön- nen. Nichteinhaltung der Zahlungsbedingungen berechtigen uns zur Einstellung der Lieferung.

DRG Instruments GmbH Frauenbergstraße 18 D-35039 Marburg Tel. +49 (0) 64 21/17 00-0, Fax +49 (0) 64 21/17 00-50 Internet: www.drg-diagnostics.de E-mail: [email protected]

88 Allgemeine Geschäftsbedingungen Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 89

General Terms and Conditions

1 Handling Permittance 6 Reservation of proprietary rights Radioactive reagents may only be supplied to companies or We keep the ownership of the goods delivered until payment persons possessing a handling permittance (Radiation Protec- is concluded. Preventive transference and preventive sale or tion Act of June 30, 1989). mortgage of goods being reserved as our property is inadmis- sible. The reservation of our proprietary rights is not affected by claims, taken on a current invoice by rehabilitating and accepting the balance. 2 Orders The customer acknowledges our General Terms and Conditi- ons by placing an order. Any deviant agreements require our written confirmation. Delivery cantract becomes valid with 7 Complaints our order confir-mation. The customer has to charge complaints in written form within one week after receipt of goods. The time we receive the complaint is decisive. Faulty goods are to be returned at our disposal, strictly subject to our declaration of consent in 3 Prices written form. Prices do not include freight charges. All prices are subject to change without prior notice. Invoices are issued at prices valid for the day on which delivery is executed. 8 Place where the contract is to be fulfilled Marburg, Germany 4 Delivery All deliveries are being effected at the buyer’s risk. DRG does not take on any responsibility for damages and its consequen- 9 Court of Jurisdiction ces and refuse any compensations. We are exempt from any Court of jurisdiction, also in case of bills of exchange or delivery obligations in cases of circumstances, which to sort is cheque transactions is Marburg, Germany. beyond our control and which make it impossible or inaccep- table for us to execute delivery. In case of any justified complaints being faultless replacement or by creditin the amount. Further claims, especially entitlements to compensation due to non-delivery or late delivery as well as for any other real 10 Commitments and Conditions or legal reason are (so far as permissible in law) rejected. By placing an order the customer accepts the preceding terms of sale. Divergent conditions or verbal arrangements are not definite unless we acknowledge them in written form. Possible legal inoperativeness of any part of these General Terms and Conditions have no influence on their further content’s legal 5 Payment force. Our invoices are to be paid by prepayment less 2 % cash discount or at 30 days net. For default of payment we charge 2 % interest (exceeding the official discount rate). Payment is not valid until we have the total amount at our disposal. Non-observance of our payment conditions entitles us to cease delivery.

DRG Instruments GmbH Frauenbergstraße 18 D-35039 Marburg Tel. +49 (0) 64 21/17 00-0, Fax +49 (0) 64 21/17 00-50 Internet: www.drg-diagnostics.de E-mail: [email protected]

General Terms and Conditions 89 Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:27 Seite 90

Abkürzungen Serviceleistungen

1. Assaytype Auftragsannahme und Lieferservice Bestellungen können Sie telefonisch, schriftlich, per Telefax oder e-mail bei uns aufgeben. ELISA (Enzyme Linked Immuno Sorbent Sie erreichen uns während der üblichen Geschäftszeiten: Assay) Montags bis Freitags von 8.00 - 16.30 Uhr. Der ELISA ist eine heterogene, immunologische Bestimmung biologisch aktiver Substanzen in Kör- Wir bemühen uns, Bestellungen, die wir bis 13.00 Uhr erhalten, perflüssigkeiten. Dabei wird die Reaktion zwischen noch am selben Tag auszuführen. Antigen und spezifischem Antikörper durch die Die termingerechte Anlieferung innerhalb von 24 Stunden erledigt nachfolgende Bestimmung eines an das Antigen ein von uns beauftragtes, zuverlässiges Transportunternehmen oder den Antikörper gebundenen Enzyms nachge- (Fa. UPS/TNT). wiesen. Man unterscheidet zwischen kompetitiven und Bei regelmäßigem Bedarf empfehlen wir Ihnen unseren Dauerliefer- Sandwich Assay. service. Sie erhalten die Produkte zu den vereinbarten Terminen und können Abweichun- Der Test eignet sich vor allem für Medikamente, gen von dem genannten Bedarf kurzfristig telefonisch veranlassen. Hormone und Proteine und umgeht bei ähnlicher Empfindlichkeit wie ein RIA den Umgang mit Bestellungen aus Deutschland oder aus EU-Ländern: radioaktiven Stoffen. Telefon +49 (0) 64 21/17 00-14 Auftragsannahme (Birgit Ammenhäuser) Telefon +49 (0) 64 21/17 00-29 Auftragsannahme RIA (RadioImmunoAssay) (Yvonne Leinweber) Dieser kompetitive Immunoassay ist eine etablierte e-mail: [email protected] Methode zur Bestimmung niedriger Konzentrationen von Proteinen und nidermolekularen Substanzen. Telefon +49 (0) 64 21/17 00-0 Zentrale Die Antigenmoleküle und eine konstante Menge Tracer Telefax +49 (0) 64 21/17 00-50 konkurrieren um Bindung an eine vorliegende Menge e-mail: [email protected] des spezifischen Antikörpers. Die nicht gebundenen Teile werden durch Waschen ent- fernt. Beratung und technischer Kundendienst Durch Vergleich der gemessenen Radioaktivität mit Sie haben Fragen zur Testdurchführung? Sie haben ein technisches einer Standardkurve erhält man die Konzentration des Problem? Rufen Sie uns doch einfach an! Unsere wissenschaftlichen gesuchten Analyten. Mitarbeiter beraten Sie gerne und helfen Ihnen bei technischen Problemen und Fragen.

Läßt sich das Problem am Telefon nicht lösen, wird Sie schnellstmöglich einer unserer Mit- arbeiter in Ihrem Labor aufsuchen und Ihnen vor Ort helfen. IRMA (ImmunoRadioMetricAssay) Zweiseitiger immunoradiometrischer Assay mit zwei Bitte wählen Sie: Antikörpern (einer in Lösung, der andere an einer fest- Telefon +49 (0) 64 21/17 00-23 (Julia Räder) en Phase gebunden) gegen verschiedene Epitope des e-mail: [email protected] Analyten. Schulungen Wir veranstalten in regelmäßigen 2. Methode: Abständen Workshops zur Einarbeitung in die ELISA-Technologie sowie Schulun- CB: Coated Beads gen zu den neuesten Entwicklungen im BIO: Mikrobiologischer MTP Assay Bereich der medizinischen Diagnostik. CLA: Chemilumineszenz-Immunoassay Daneben werden laufend interne CT: Coated Tubes Schulungen im Rahmen unseres Qualitäts- DA: Double Antibody management-Systems durchgeführt. DCC: Dextran Coated Charcoal DOT: Dot Blot EIA: Enzymimmunoassay ENZ: Colorimetrischer MTP Assay MTPL: MicrotiterPlate Bitte fordern Sie detaillierte Informationen zu unseren Produkten RAP: Schnelltest telefonisch oder per E-Mail an: RLA: Radio Ligand Assay RRA: Radio Receptor Assay [email protected] SLV: Speichel ELISA Gerne unterbreiten wir Ihnen ein auf ihren Bedarf maßgeschneidertes Angebot, welches Ihnen erlaubt, Ihre Tests zuverlässig und rentabel abzuarbeiten.

Unsere Produkte finden Sie auch im Internet unter: www.drg-diagnostics.de www.drg-international.com 90 Abkürzungen Preisliste aktuell 10.2011_Preisl. 2006_04 o.Preis_drg 04.11.11 12:28 Seite 91

Abbreviations

1. Assaytype 2. Method BIO: Microbiological MTP Assay ELISA (Enzyme Linked Immuno CB: Coated Beads Sorbent Assay) CLA: Chemiluminescence Immunoassays CT: Coated Tubes The ELISA (Enzyme Immuno Assay) is heteroge- DA: Double Antibody neous, immunological determination of substances DCC: Dextran Coated Charcoal in body liquids. The reaction between antigen and DOT: Dot Blot specific antibody is assayed by determination of an EIA: Enzymimmunoassys enzyme which is conjugated to the antigen or anti- ENZ: Colorimetric MTP Assay body. ELISAS may be designed as competitive or MTPL: MicrotiterPlate sandwich assays. ELISAS are used for the determi- RAP: Rapid Screen Test nation of drugs, hormones and proteins and avoid RLA: Radio Ligand Assay handling of radioactive substances at a similar sen- RRA: Radio Receptor Assay sitivity as a RIA. SLV: Saliva ELISAS RIA (RadioImmunoAssay) This competitive immunoassay is an etablished method for the determination of very low concentrations of proteins and other substances. The analyte molecules and a constant amount of tracer compete against a specific antibody. Excessive tracer is removed by washing. Comparison of the measured radioactivity with a standard curve allows the determination of the analyte concentration.

IRMA (ImmunoRadioMetricAssay) Double sided immunoradiometric assay with two antibodys (one in solution the other bound to a solid phase) against different epitopes of the analyte.

If you wish to obtain further information on our products or technical data on our assays, please visit our WEBSITE at: www.drg-diagnostics.de www.drg-international.com

Abbreviations 91 Preisliste aktuell 10.2011_B+F_Preisl. 2006_04 o.Preis_drg 07.11.11 09:55 Seite 92

The DRG Group

Germany USA Headquarters DRG Instruments GmbH DRG International, Inc. Division of DRG International, Inc. 1167 U.S. Highway 22 East Frauenbergstraße 18 Mountainside, N.J. 07092 USA D-35039 Marburg, Germany Tel: +1 (9 08) 2 33-20 79 Tel: +49 (0) 64 21 17 00-0 Fax: +1 (9 08) 2 33-07 58 Fax: +49 (0) 64 21 17 00-50 Dr. C. Geacintov Mr. Saenger, Dr. Roeder E-Mail: [email protected] E-Mail: [email protected] www.drg-international.com www.drg-diagnostics.de

China Czech Republic DRG International Inc. DRG spol. s.r.o. Beijing office Sumavska 33 German Center for Industry and Trade 61254 Brno, Czech Republic Unit 912, Landmark Tower 1 Tel/Fax: 420 (5) 41 23 53 26 8 North Dongsanhuan Road Dr. Pavel Giacintov Chaoyang District E-Mail. [email protected] Beijing 100004 P. R. China Tel: 86 (10) 6590 0239 Fax: 86 (10) 6590 0231 E-Mail: [email protected] www.drg-international.com.cn

Poland Poland DRG MedTek Sp. zo.o. DRG MedTek South Poland ul. Wita Stwosza 24 ul. Piotra Skargi 28 02-661 Warszawa, Poland 44-100 Gliwice, Poland Tel: 48 (22) 8 47 82 44 / 8 47 83 75 Mr. Witold Jurkiewicz Fax: 48 (22) 8 43 72 74 E-Mail: [email protected] Mr. Witold Jurkiewicz www.drg.alpha.pl E-Mail: [email protected] www.drgmedtek.pl

Russia - Moscow Russia - St. Petersburg DRG TechSystems DRG Biomed O.O.O. T. Shevchenko Embankment 3, ul. Serdobolskaja - 1# 183 121248, Moscow, Russia St. Petersburg 19 41 56, Russia Tel: 7 (495) 2 43-52 28 / -56 21/-40 28 Tel: 7 (812) 4 92 56 93 Fax: 7 (495) 2 43-93-00 Fax: 7 (812) 4 96 00 47 Mr. Dmitri Kekalo Dr. V. Berezin E-Mail: [email protected] E-Mail: [email protected] www.drgtech.ru

If you wish to obtain further information on our products or technical data on our assays, please visit our WEBSITE at: www.drg-diagnostics.de www.drg-international.com

92 DRG Group