ASNC 2019 ASNC President @Beanlandsrob

ASNC Policy 2019 SEPTEMBER 12-15, 2019 Special Sessions Intersocietal CHICAGO, ILLINOIS Multimodality Imaging Advanced PET

Cases with the Aces

Abstracts Plenary Team-based Learning Technology Social Media and Techniques Rapid Fire ePosters Image-based Case Management

BE IN THE CONNECT. LEARN. LOOP! DELIVER. FINAL PROGRAM Expected results. Delivered.

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Indication for Use: RUBY-FILL is a closed system used to produce rubidium (Rb-82) chloride injection for intravenous use. Rubidium (Rb-82) chloride injection is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease. New Important Safety Information April 2019 Please note changes in Boxed Warning, Dosage and Administration, Directions for Eluting Rubidium Rb 82 Chloride Injection (2.5), Contraindications (4), Warnings and Precautions, High Level Radiation Exposure with Use of Incorrect Eluent (5.1).

WARNING: HIGH LEVEL RADIATION EXPOSURE WITH USE OF INCORRECT ELUENT AND FAILURE TO FOLLOW QUALITY CONTROL TESTING PROCEDURE Please see full prescribing information for complete boxed warning High Level Radiation Exposure with Use of Incorrect Eluent Using the incorrect eluent can cause high Strontium (Sr 82) and (Sr 85) breakthrough levels (5.1) • Use only additive-free 0.9% Sodium Chloride Injection USP to elute the generator (2.5) • Immediately stop the patient infusion and discontinue the use of the affected RUBY-FILL generator if the incorrect solution is used to elute the generator (4) • Evaluate the patient’s radiation absorbed dose and monitor for the effects of radiation to critical organs such as bone marrow (2.9) Excess Radiation Exposure with Failure to Follow Quality Control Testing Procedure Excess radiation exposure occurs when the levels of Sr 82 or Sr 85 in the rubidium Rb 82 chloride injection exceed specified limits (5.2) • Strictly adhere to the generator quality control testing procedure (2.6) • Stop use of a generator at any of its Expiration Limits (2.7)

The risk information provided here is not comprehensive. Please visit RUBY-FILL.com for full Prescribing Information including BOXED WARNING. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/Safety/MedWatch or call 1-800-FDA-1088.

References: 1. RUBY-FILL [package insert]. Kirkland, Quebec, Canada: Jubilant DraxImage Inc; April 2019. 2. Renaud JM, Wiles M, Garrard L, Beanlands RSB, deKemp RA. New rubidium-82 generator efficiency improves over time.J Nucl Med. 2018;59(suppl 1):1045. 3. Lewin HC, Millard A. Dose accuracy of 82Rb generator systems. Paper presented at: SNMMI Mid-Winter Meeting; January 17–19, 2019; Palm Springs, CA.

RUBY-FILL® is a registered trademark used under license by Jubilant Draxlmage, Inc. Jubilant DraxImage Inc. dba Jubilant Radiopharma, 16751 Trans-Canada Highway, Kirkland, Quebec, Canada H9H 4J4 Phone: 1.888.633.5343 / 514.630. 7080 Fax: 1.866.431.4288 / 514.694.3865 www.jubilantradiopharma.com © Jubilant DraxImage Inc. 2019-US-RUBY-00018 ORGANIZING COMMITTEE TABLE OF CONTENTS Sharmila Dorbala, MD, MPH, FASNC, Chair Karthik Ananthasubramaniam, MD, FASNC President’s Welcome...... 3 Danny A. Basso, CNMT, NCT Chair’s Welcome...... 3 Rob S.B. Beanlands, MD, FASNC ASNC2019 Supporters...... 5 Donna M. Polk, MD, MPH, FASNC Ron Schwartz, MD, MASNC ASNC Education...... 6 Prem Soman, MD, PhD, MASNC Program Tracks...... 8 PROGRAM COMMITTEE Schedule by Track...... 9 Panithaya Chareonthaitawee, MD, Chair Industry Sponsored Satellite Symposia...... 14 Terrence D. Ruddy, MD, FASNC, Vice Chair Program Schedule...... 18 Niti R. Aggarwal, MD, FASNC Firas J. Al Badarin, MD, FASNC ASNC International Partners...... 58 Mouaz Al-Mallah, MD, FASNC Mobile App...... 58 Ron Blankstein, MD, FASNC General Information...... 59 Jamieson M. Bourque, MD, FASNC Renee Bullock-Palmer, MD, FASNC Venue Maps ...... 60 Dennis A. Calnon, MD, MASNC Exhibitor Listing...... 64 Benjamin Chow, MD, FASNC Paul Cremer, MD ASNC2020 Save the Date...... 70 Sarah Cuddy, MB ChB ASNC2019 Faculty...... 74 Marcelo Di Carli, MD, FASNC Vasken Dilsizian, MD, MASNC Author/Faculty Index...... 77 Sharmila Dorbala, MD, MPH, FASNC Rami Doukky, MD, MSc, FASNC W. Lane Duvall, MD, FASNC www.asnc.org/ASNC2019 Andrew J. Einstein, MD, PhD, FASNC Ernest V. Garcia, PhD, MASNC Robert J. Gropler, MD, MASNC Fadi G. Hage, MD, MASNC Thomas A. Holly, MD, FASNC Mark C. Hyun, CNMT, NCT, RT(N), FASNC Wael Jaber, MD Scott D. Jerome, DO, FASNC Nils J. Johnson, MD Saurabh Malhotra, MD, MPH, FASNC Edward J. Miller, MD, PhD, FASNC Shivda Pandey, MD Donna M. Polk, MD, MPH, FASNC Raymond R. Russell, MD, PhD, MASNC Rupa Mehta Sanghani, MD, FASNC Nishant Shah, FASNC Al J. Sinusas, MD, FASNC Piotr J. Slomka, PhD Gary R. Small, MB ChB, PhD Viviany Taqueti, MD, MPH Randall Thompson, MD, FASNC Peter Tilkemeier, MD, MASNC Richard Weinberg, MD, PhD, FASNC THE BRANDS Bringing YOU KNOW THE QUALITY Physiology YOU TRUST and Function to Light on the Pathway of Patient

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TechneLite, NEUROLITE, Cardiolite, QUADRAMET and corporate logo display are registered trademarks of Lantheus Medical Imaging, Inc. ©2019 Lantheus Medical Imaging, Inc. All rights reserved. NUC 112 April 2019 PRESIDENT’S WELCOME CHAIR’S WELCOME I am pleased to welcome you to Dear Colleagues, ASNC2019 at the Chicago Marriott On behalf of the Program Committee, I am Magnificent Mile. We are honored delighted to welcome you to ASNC2019! We to have you all with us for this are looking forward to four wonderful days to exciting meeting. connect as a community and learn about the Panithaya Chareonthaitawee, many exciting developments that the future holds MD and her committee have for nuclear cardiology. I hope you’ll be energized designed an unparalleled opportunity to participate by the breadth of the ASNC2019 program and by the diversity of in personalized, real-world, collaborative education both our faculty and ASNC’s membership. We are fortunate to have focused on quality imaging for optimal patient care. deep and varied scientific and medical backgrounds that support Network and interact with physicians, scientists, our mission of improving cardiovascular outcomes through image- technologists, nurses, colleagues in industry and many guided patient management. others from around the world. ASNC2019 is possible because of the expertise and insights of my co- This year’s annual meeting begins with Clyde Yancy, chair, Terry Ruddy, MD, FASNC; the Program Committee; our outstanding MD, MSc, Cardiology Chief and Vice Dean for Diversity faculty; and ASNC’s dedicated staff. I thank them for their efforts and for and Inclusion at Northwestern University, Feinberg embracing our goal of creating a meeting where we all will Be In The School of Medicine, and his plenary lecture “Addressing Loop, with robust opportunities to Connect, Learn & Deliver. Cardiovascular Disease Disparities: Are We Getting ASNC2019 is packed with interactive sessions and networking events, Closer to the Truth?” all designed to help you connect with faculty, other attendees, friend And don’t miss the 2019 Mario Verani Lecturer, John industry partners and ASNC leaders. ASNC’s popular Cases with the Mahmarian, MD, MASNC, Medical Director of Nuclear Aces, Image-based Case Management, Team-based Learning and Cardiology and Computed Tomography (CT) Services at Walk & Learn Tours are back based on your positive feedback, plus Houston Methodist DeBakey Heart & Vascular Center, we’ve amped up the interactivity with the new Scintillating Learning who will present “A Tale of Two Imaging Technologies: Through Social Media and the Learn with Leaders Hands-on Lab. Be Can Nuclear Cardiology Survive the Emergence of sure to take advantage of the time we’ve built into all of the sessions Cardiac CT?“ on Thursday, Sept. 12 at 5:00 p.m. for you to share your thoughts, questions, challenges and solutions. Thank you for your attendance and support all year- Take time to connect with mentors, colleagues and new friends at round. We would also like to thank our industry partners happy hour activities in the exhibit hall and special events in the for their contributions and I invite you to visit them in new Networking Lounge. And expand your reach even further by the Exhibit Hall to learn about the latest advances in engaging the #ASNC2019 conversations occurring on social media. imaging hardware and software. (New to social media? We’ve also got you covered with a new social media training track.) It is exciting to be part of the field of nuclear cardiology. There are many scientific advances and the field We’ve deployed nuclear cardiology’s best and brightest experts continues to grow and evolve. We have a wonderful across the 12 tracks that reflect where our specialty is today and community of professionals and it is at these meetings where it’s going in the future. No matter what you’re aiming to learn, we grow even stronger. You are ASNC! we have you covered with essential SPECT and cardiac PET protocols, the how-to’s of disease-based care, and the practical challenges of We would like to thank our industry partners for their running a successful nuclear cardiology and imaging practice. While contributions and I invite you to visit them in the Expo I couldn’t possibly list all of the sessions I’d like to recommend, I urge Hall to learn about the latest advances in imaging you to attend Dr. Clyde Yancy’s important keynote on cardiovascular hardware and software. Thank you for your attendance disease disparities and Dr. John Mahmarian’s Mario Verani lecture, “A and engagement all year-round. Tale of Two Imaging Technologies: Can Nuclear Cardiology Survive the The combination of the scientific content, the networking Emergence of Cardiac CT?” opportunities and the vibrant city of Chicago, is sure to From these and ASNC2019’s many other sessions and activities, you’ll yield an outstanding ASNC meeting. Enjoy! refresh your skills, acquire new knowledge, and return home ready to deliver high-quality cardiovascular imaging to more patients in need. I look forward to connecting with you in Chicago and on social media. Tag me @PanithayaC. Rob S. B. Beanlands, MD, FASNC 2019 ASNC President @BeanlandsRob

Panithaya Chareonthaitawee, MD ASNC2019 Program Chair @PanithayaC

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 3 MAYOR’S WELCOME American Society of Nuclear Cardiology would like to thank the International Dear Friends: Atomic Energy Agency (IAEA) for their As Mayor, and on behalf of the City of third year of generous support of live Chicago, I am honored to welcome all streaming of ASNC’s annual scientific those gathered for the Annual Scientific sessions to physicians, technologists Session of the American Society of and other colleagues working in Nuclear Cardiology. developing countries. The American Society of Nuclear Cardiology (ASNC) was founded in 1993 by a group of nuclear cardiologist specialists who saw the need for a professional society dedicated to supporting the needs of those in the specialty. Since its inception, ASNC has grown to over 4,000 members across the world composed of cardiologists, radiologists, physicians, scientist, technologists, imaging specialists, and others in the field of nuclear cardiology. ASNC remains committed to the mission of providing professional education, establishing standards and SO MANY SESSIONS, guidelines for training and practice, advocating for cardiovascular imaging, and supporting members with the SO LITTLE TIME goal of moving nuclear cardiology forward. ASNC2019 MEETING This year’s session will bring over a thousand physicians, ON DEMAND scientists, technologists, and nurses in the field of nuclear cardiology together to network, learn, and inspire. With a full schedule of keynote speakers, PET Lab Tours, Walk & Learn Tours, exhibits, workshops, and networking events, attendees will have the opportunity to participate in a real- world, collaborative education focusing on innovative and quality imaging for optimal patient care. I commend the American Society of Nuclear Cardiology for their continued MOD work in moving the field forward and bringing the best possible care to patients.

I hope that during your stay in Chicago you take the time to see all the City has to offer. Vibrant neighborhoods, an Information about purchasing iconic skyline, and an incredible lakefront invites you to explore Chicago. I hope you have a chance to explore The a CME MOD are provided on 606 Trail and historic South Shore Cultural Center, tour the asnc.org and at registration. vibrant neighborhoods across our city, sample our diverse Earn CME credit for the session cuisine, tour our distinguished universities, and visit our you couldn’t attend with ASNC2019 world-class museums during your stay. Meeting On Demand. I hope your event is memorable and enjoyable. Best wishes for continued success. Claim Your Special Attendee Discount Order during the meeting and pay only

Lori E. Lightfoot Mayor $199

*$199 for members and $249 for non-members. Special offer ends September 15, 2019.

4 www.asnc.org/ASNC2019 ASNC2019 SUPPORTERS

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#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 5 ASNC EDUCATION

PROGRAM DESIGN: technologists. ASNC’s CE credit is accepted by both NMTCB and ARRT. ASNC 2019 has been approved for a maximum of • A scientific forum featuring panel discussions on focused 27* ARRT Category A Credits for technologists. areas of cutting-edge research • State-of-the-art reviews of the key aspects of nuclear Physician Assistants: The American Academy of Physician cardiology by the world’s experts Assistants (AAPA) accepts certificates of participation for TM • A basic core curriculum addressing practical issues in the educational activities certified forAMA PRA Category 1 Credits performance of nuclear cardiology procedures to include from organizations accredited by ACCME. opportunities for maintenance of certification credit Nurse Practitioners: The American Academy of Nurse • Scientific sessions on advances in nuclear cardiology Practitioners Certification Board (AANPCP) recognizes • Ethics session will offer case based scenarios dealing with attendance at CE offerings which provideAMA PRA Category 1 ethical issues CreditsTM for the purpose of recertification. • Intersocietal Multimodality Imaging track dealing with Maintenance of Certification the pathophysiology of multimodality imaging Successful completion of this CME activity, which includes • Presentations addressing technical issues in nuclear participation in the evaluation component, enables the cardiology participant to earn up to 28.5* medical knowledge Maintenance • Oral abstracts featuring the latest clinical studies in of Certification (MOC) points in the American Board of Internal cardiovascular imaging Medicine’s (ABIM) MOC program. Participants will earn MOC • Abstracts of original investigation programmed as Rapid points equivalent to the amount of CME credits claimed for the Fire, poster and e-poster presentations activity. It is the CME activity provider’s responsibility to submit • Sessions offering Maintenance of Certification points participant completion information to ACCME for the purpose • Commercial exhibits displaying the latest in nuclear of granting ABIM MOC points. cardiology technology and services • Cost-related information in the practice and business of nuclear cardiology *subject to change • Cases with the Aces with experts demonstrating how to read a scan with specific vendor software CLAIMING CME OR CE CREDITS • Opportunities to convene and interact with experts in all To receive your CME/CE credit certificate, aspects of nuclear cardiology and cardiovascular imaging you must complete the online evaluation by November 1, 2019. Please follow these STATEMENT OF NEED steps: 1. Visit the Itinerary Planner at https://www. In order to maintain competence and improve performance, abstractsonline.com/pp8/#!/7885 or by imaging professionals must assimilate and integrate using your smart phone’s camera or a QR reader to read this knowledge spanning multiple areas, including clinical data, QR code. technical aspects of imaging, and appropriate application of 2. Sign in using your registration reference number and your imaging (e.g., clinical guidelines and appropriate use criteria). last name. Your reference number is located on your badge Each of these areas is constantly evolving, particularly as and is also in the registration confirmation you received. innovative technologies and novel pharmacologic agents are 3. Select the sessions you attended. introduced. ASNC2019 is an educational activity designed to 4. Complete the individual evaluations for the sessions you help you and other imaging professionals obtain the latest attended. information in clinical practice and review cutting-edge 5. Complete the overall evaluation after you complete all scientific advances in nuclear cardiology and cardiac imaging. individual session evaluations. 6. Select the link to download your CME or CE certificate. ACCREDITATION AND CONTINUING EDUCATION CREDIT Participants will receive an email with the evaluation link and Physicians: The American Society of Nuclear Cardiology instructions immediately after the meeting to help remind is accredited by the Accreditation Council for Continuing participants to claim credit by the deadline date. If you have Medical Education (ACCME) to provide continuing medical not received an email please contact [email protected] education for physicians. ASNC designates this live activity for a maximum of 28.5* AMA PRA Category 1 CreditsTM. Physicians DISCLOSURE should claim only the credit commensurate with the extent of their participation in the activity. ASNC is pledged to ensure balance, independence, objectivity, and scientific rigor in all its supported educational Technologists: The American Society of Nuclear Cardiology activities through disclosure of relationships with commercial is a recognized provider of continuing education credit for

6 www.asnc.org/ASNC2019 ASNC2019 CONFLICT OF INTEREST RESOLUTION FOR ASNC2019

ASNC Board of Directors (BOD) and Committee Members have ASNC Staff completes completed annual financial disclosures. If a potential COI exist, disclosure forms it is vetted through the Education Committee and BOD; Chair of Annual Meeting is selected by the BOD and Executive Council

ASNC Staff reviews all disclosures and identifies potential COI’s for planners, moderators, reviewers and presenters

If speaker does not disclose If speaker has no conflicts, speaker is disqualified speaker is accepted If COI is identified

For moderate to high COI, speakers must For low COI, presentations are reviewed submit presentations in advance for review via the moderators form onsite

Presentations are reviewed by the If presentations are not Annual Meeting Chair/Co-chair received in advance and Working Group Chairs speakers are disqualified

All session moderators are provided an onsite moderator form and are instructed to disqualify faculty if COI is in conflict with content of presentation

companies and resolution of conflict of interest. All planners, GENERAL LEARNING OBJECTIVES moderators, reviewers, and presenters involved with this activity are expected to disclose financial interests with • Demonstrate improved skills in image interpretation and the manufacturer(s) of any commercial product(s) and/or reporting providers of commercial services discussed in an educational • Learn how to recognize and minimize technical problems presentation. A complete list of disclosures will be distributed and artifacts that may be associated with cardiac imaging to all attendees on-site. The American Society of Nuclear • Learn the appropriate use of cardiac imaging techniques Cardiology has reviewed this activity’s faculty disclosures and based on current guidelines resolved or managed all identified conflicts of interest. • Evaluate new imaging technologies, software, and stress techniques • TARGET AUDIENCE Understand the role of nuclear and cardiac CT imaging in This conference is intended for cardiologists, radiologists, overall patient care nuclear medicine specialists, practice administrators, nuclear • Learn the importance of balancing radiation exposure with technologists, nurses, and other health care professionals with image quality an interest in the field of nuclear cardiology. • Describe future directions in cardiac PET, CT, and SPECT/CT in order to anticipate training and equipment needs Overall Purpose: This activity will increase learners’ competence • Understand the clinical implication of CT coronary in solving technical and clinical issues when treating patients with angiography and recognize its value and limitations in CVD. Sessions will present different approaches to cardiac disease clinical cardiology management to how best improve patient outcomes. These sessions will address topics in appropriate use criteria, SPECT best Acknowledgement of Commercial Support practices, PET best practices, new and emergent cardiac imaging This activity is supported in part by an educational grant from Pfizer. procedures, lab performance and procedures, radiation safety, reporting, and lab performance and the application of appropriate guidelines-based treatments.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 7 ASNC EDUCATION

PROGRAM TRACKS Mix and match sessions from across ASNC’s 12 tracks based on your own interests and priorities for a unique meeting personalized just for you. Advanced PET Technology and Techniques Attend these eye-opening sessions This track is PET headquarters. You Developed for technologists, this for updates on cutting-edge will get all of your questions answered track focuses on nuclear cardiology nuclear cardiology technology by faculty who are leading the way procedures. Attend these interactive and innovations, with an emphasis with this powerful imaging modality. sessions for practical guidance on clinical application for optimal on how to provide quality imaging outcomes. Plenary services. Join your nuclear cardiology Cases with the Aces: Interactive community for keynote presentations Reading forecasting how emerging ASNC Booth Hours: Back by popular demand! Roll up technologies, applications and Thursday, September 12 your sleeves and join small-group priorities will impact our field. Prepare 11:00 am – 8:00 pm sessions, each led by faculty from for the future, and help shape it! 5th and 7th Floor Foyer* premier nuclear cardiology training Friday, September 13 programs. You’ll interpret scans Policy 8:30 am – 4:30 pm using commercial software. It’s the Advocacy experts will provide 7th Floor Foyer closest thing to being mentored in updates on health policy issues that your own lab.. are changing how clinical care is Saturday, September 14 delivered and valued. This track will 8:30 am – 4:30 pm th Image-based Case Management provide essential background for 7 Floor Foyer Also known as Read with the Experts, healthcare administrators as well as • Sign up to become an this signature ASNC track is a current and future physician leaders. ASNC Ambassador, perennial favorite. Master clinicians so you can promote will detail how they use imaging to Research/Abstracts the value of being an manage complex cardiovascular Poster and oral abstract ASNC member! diseases.. presentations, young investigator • Take home a Chicago souvenir! oral presentations and competition Make a minimum donation of Intersocietal Multimodality Imaging geared toward basic science and $250 to the IANC Research Fund Representatives from the medical clinical research. and receive a pair of Chicago societies that collaborate on nuclear Transit Authority socks cardiology guidelines, including Special Sessions • Become a 2020 ASNC member patient representatives, will Looking for outside-the-track and receive an ASNC mug. If you participate in this interactive track. educational experiences? Special become a member for 2-years, Attend these sessions for insight into Sessions is home to ethical receive an ASNC hat and mug the research and questions that are considerations, interactive walking While supplies last! driving guidelines and standards of tours, awards and other fun, collegial • Show your ASNC pride! care. learning opportunities. These Purchase ASNC gear and 10% of sessions are a special treat. Indulge! all purchases will go to the IANC Scintillating Learning through Research Grant Award Program. Social Media Team-based Learning • Pick Up ASNC Practice Points Innovative learning through social Global nuclear cardiology teams and Guidelines/Order ASNC media. Discover ways social media share creative solutions to practical Practice Points and Guidelines in can help you stay abreast in the field day-to-day problems in clinical bulk and they can be shipped to of nuclear cardiology, improve your practice. These sessions are geared your practice. practice, benefit your career and towards the entire nuclear imaging *On the 5th floor until 6:00 pm. On the 7th floor impact your patients. team. 6:00 – 8:00 pm.

8 www.asnc.org/ASNC2019 ASNC2019 SCHEDULE AT-A-GLANCE

ImageGuide Registry Booth Hours: Thursday, September 12 • Visit the ImageGuide Registry booth for a personalized demo on how 6:45 pm – 8:00 pm – 7th Floor Foyer the registry can transform your lab in the areas of patient safety and Friday, September 13 quality improvement. 8:30 am – 4:30 pm – 7th Floor Foyer • Learn about the nation’s first registry for non-invasive cardiac imaging Saturday, September 14 aimed at tracking and improving quality for the benefit of patient care. 8:30 am – 4:30 pm – 7th Floor Foyer • Ask your questions on the Merit-Based Incentive Payment System (MIPS) and how the ImageGuide Registry can help with reporting requirements in 2019.

TUESDAY, SEPTEMBER 10 4:00 pm – REGISTRATION OPEN 7:00 pm 5th Floor

WEDNESDAY, SEPTEMBER 11 6:00 am – REGISTRATION OPEN 7:00 pm 5th Floor 6:30 am – Board Exam Preparation Course 6:00 pm Chicago Ballroom D, 5th Floor

THURSDAY, SEPTEMBER 12 6:00 am – REGISTRATION OPEN 7:00 pm 7th Floor 6:30 am – Board Exam Preparation Course 4:30 pm Chicago Ballroom D, 5th Floor 12:00 pm - Opening Keynote 1:00 pm Keynote – Clyde W. Yancy, MD Addressing Cardiovascular Disease Disparities – Are We Getting Closer to the Truth? Marriott Ballroom, 4th Floor 1:00 pm – Networking Break 2:00 pm Connect with your fellow colleagues

2:00 pm – Image-Based Case Team-Based Learning 2:00 pm – 4:00 pm 3:30 pm Management Best Practices for Radiation Reduction Offsite Demographics Dictate: Evaluating Belmont, 4th Floor PET Lab Tour Ischemia in Special Populations PET: Cardiac Program at Rush Armitage, 4th Floor University 3:45 pm – Intersocietal Multimodality Policy Meet at 7th Floor Registration at 1:15 pm 5:00 pm Imaging Overview: ASNC and Reimbursement Shuttle departs at 1:30 pm Imaging for CAD: Which Test is Advocacy Shuttle support provided by Best for Pain in the Chest? Belmont, 4th Floor Siemens Healthineers Armitage, 4th Floor

LEARNING LEVELS Core Intermediate Advanced Expert *Schedule is subject to change.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 9 ASNC2019 SCHEDULE AT-A-GLANCE

THURSDAY, SEPTEMBER 12 5:15 pm – President’s Session and Mario Verani Lecture 6:30 pm Welcome and Introduction of ASNC President – Kathleen Flood, CEO ASNC President’s Welcome and Introduction of Program Chair – Rob S.B Beanlands, MD, FASNC ASNC2019 Program Overview – Panithaya Chareonthaitawee, MD ASNC2019 Program Chair Recognition – Rob S.B Beanlands, MD, FASNC ASNC President’s Address – Rob S.B Beanlands, MD, FASNC Presentation of Leadership Award – Sharmila Dorbala, MD, MPH, FASNC President-Elect’s Address – Sharmila Dorbala, MD, MPH, FASNC Introduction of Mario Verani Lecturer – Manuel D. Cerqueira, MD, MASNC Mario Verani Keynote Lecture - A Tale of Two Imaging Technologies: Can Nuclear Cardiology Survive the Emergence of Cardiac CT? – John J. Mahmarian, MD, MASNC Chicago Ballroom D, 5th Floor 6:30 pm – Welcome Reception and Opening of the Expo Hall 7:45 pm Expo Hall, 7th Floor 6:45 pm – Posters – Foyer of Grand Ballroom 7:45 pm Rapid Fire ePosters – South Alcove, 7th Floor ePosters – North Alcove, 7th Floor

FRIDAY, SEPTEMBER 13 7:00 am – REGISTRATION OPEN 7:00 pm 7th Floor 8:30 am – EXPO HALL OPEN (Closed 12:30 – 1:15 pm) 4:30 pm Expo Hall, 7th Floor 6:30 am – Breakfast Workshop (non-CME) 7:45 am Hereditary Amyloid Transthyretin (hATTR) Amyloidosis: A Clinical Diagnostic Approach Sponsored by Akcea Therapeutics Marriott Ballroom, 4th Floor 7:45 am – ASNC/ACC: Your Societies Working for You – Rob S.B. Beanlands, MD, FASNC and Athena Poppas, MD 8:05 am Pamela S. Douglas, MD - Distinguished Career Award William D. Nelligan, III, CAE, FACC, MASNC - Distinguished Service Award Chicago Ballroom D, 5th Floor 8:05 am – Plenary 9:30 am Quantitative Perfusion Imaging: Time to Go with the Flow Chicago Ballroom D, 5th Floor 9:30 am – Awards Ceremony 10:00 am Chicago Ballroom D, 5th Floor 9:30 am – Posters – 7th Floor Foyer 10:30 am ePosters – North Alcove, 7th Floor 9:30 am – Technology and Techniques 10:30 am How to Recognize and Troubleshoot Imaging Artifacts Belmont, 4th Floor 9:30 am – Hands-on Simulation Lab 3:00 pm SPECT and PET Case Interpretation (non-CME) Expo Hall, 7th Floor

9:45 am – Coffee Break 10:30 am Expo Hall, 7th Floor

LEARNING LEVELS Core Intermediate Advanced Expert *Schedule is subject to change.

10 www.asnc.org/ASNC2019 FRIDAY, SEPTEMBER 13 10:30 am - Advanced Cases with the Aces Intersocietal Policy Social Media 12:00 pm Microvascular Sarcoid Heart Disease Multimodality The Coverage Breaking Boundaries: Disease: More and Inflammation: Imaging Equation: Emerging Social Media and Than Just a Small Cases from Brigham & Anomalous Trends in Nuclear Beyond Problem Women’s Hospital Coronary Artery: Cardiology Chicago Ballroom H, Chicago Ballroom Armitage, 4th Floor Detection and Chicago Ballroom G, 5th Floor E, 5th Floor Management 5th Floor Chicago Ballroom D, 5th Floor 12:15 pm – Lunch and Learn (non-CME) 1:30 pm Practical Considerations for Starting a PET Program Sponsored by Jubilant Radiopharma Marriott Ballroom, 4th Floor 12:15 pm – Young Investigator Competition – Basic Science 1:45 pm Chicago Ballroom D, 5th Floor 1:30 pm – Dessert Reception and Prize Drawing in the Expo Hall 2:00 pm Expo Hall, 7th Floor 2:00 pm – Advanced Cases with the Aces Team-Based Learning Ethics 3:30 pm New Radiotracers Integrating SPECT, PET Assessing Myocardial Viability and Ethics in Nuclear in the Pipeline and CT Calcium Scoring Inflammation Cardiology: Ageism in Chicago Ballroom and CTA: Cases from Chicago Ballroom D, 5th Floor Referral and Improving E, 5th Floor Houston Methodist the Quality of Informed Armitage, 4th Floor Consent Chicago Ballroom G, 5th Floor

3:30 pm – Cases Over Cocktails (non-CME) 4:30 pm Sponsored by Alnylam Pharmaceuticals Expo Hall, 7th Floor Posters – 7th Floor Foyer ePosters – North Alcove, 7th Floor

Technology and Techniques Practical Considerations for Technologists for Radiation Dose Reduction Belmont, 4th Floor 4:30 pm – Image-Based Cases with the Aces Machine Learning Social Media 6:00 pm Case Management PISA to PARIS: Read the Machine Learning in SPECT MPI #SoMe Session Getting to the EUROPEAN WAY: Cases Applications with the Giants: Heart of the from France and Italy Chicago Ballroom G, 5th Floor Controversies with Matter: Cardiac Armitage, 4th Floor Lifestyle Medicine and Amyloidosis Preventive Cardiology Nuclear Scans in Chicago Ballroom D, Practice 5th Floor Chicago Ballroom E, 5th Floor 6:00 pm – Tweet Up Social 6:45 pm Beer and Wine Networking Reception for Tweeters and Tweeter Hopefuls Locaton will be tweeted before the reception Follow the Social Media Ambassadors on Twitter, so you can receive the secret hashtag to tweet for admission. 6:15 pm – The Time is Now: Why Cardiac PET and its Value for Your Practice 8:00 pm Sponsored by Bracco Diagnostics Inc., MiE America, Inc., Molecular Imaging Services, and Siemens Healthineers Marriott Ballroom, 4th Floor

LEARNING LEVELS Core Intermediate Advanced Expert *Schedule is subject to change.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 11 ASNC2019 SCHEDULE AT-A-GLANCE

SATURDAY, SEPTEMBER 14 7:00 am – REGISTRATION OPEN 7:00 pm 7th Floor 8:30 am – EXPO HALL OPEN (Closed 12:30 – 1:15 pm) 4:30 pm Expo Hall, 7th Floor 6:15 am – Breakfast Workshop (non-CME) 7:45 am A New Era in the Diagnosis and Treatment of ATTR-CM Sponsored by Pfizer Rare Disease Marriott Ballroom, 4th Floor 8:00 am – Plenary 9:30 am Amyloidosis Imaging: Bones, Old Dogs and New Tricks Chicago Ballroom D, 5th Floor 9:30 am – ASNC Business Meeting 9:45 am Chicago Ballroom D, 5th Floor 9:30 am – Posters – 7th Floor Foyer 10:30 am ePosters – North Alcove, 7th Floor

Coffee Break Expo Hall, 7th Floor Technology and Techniques Case-Based Cardiac Amyloid PYP Imaging: ASNC Guidelines vs. Institutional Protocols Belmont, 4th Floor 9:30 am – Hands-on Simulation Lab 4:30 pm SPECT and PET Case Interpretation (non-CME) Expo Hall, 7th Floor 10:30 am - Image-Based Cases with the Aces Intersocietal Multimodality Policy 12:00 pm Case Management A Positron Experience: PET for Imaging Health Care Friend and Foe: Ischemia and Hibernation: Cases Cardiac Sarcoidosis: When to Policy: Achieving The Relationship of from the Cleveland Clinic Investigate and How? Success in New SPECT and CT for Armitage, 4th Floor Chicago Ballroom D, 5th Floor Paradigms Diagnosis of CAD Chicago Ballroom Chicago Ballroom E, G, 5th Floor 5th Floor 12:15 pm – Lunch and Learn (non-CME) 1:30 pm Cardiac PET? Jump In, the Water is Fine: Physician and Administrative Experiences Sponsored by Siemens Healthineers Marriott Ballroom, 4th Floor 12:15 pm – Young Investigator Competition – Clinical Research 1:45 pm Chicago Ballroom D, 5th Floor 1:30 pm – Dessert Reception and Prize Drawing 2:00 pm Expo Hall, 7th Floor 2:00 pm – Image-Based Cases with the Aces Intersocietal PET Choosing 3:30 pm Case Management SPECT as a Work Horse for a Multimodality Cardiac PET: Wisely® Augmenting Nuclear Lab: Perfusion and Imaging More Than Just Competition Relative Perfusion: Amyloid: Cases from the Imaging for Perfusion Chicago Ballroom Management University of Pittsburgh Endocarditis Chicago F, 5 th Floor of Complicated Armitage, 4th Floor and Device Ballroom E, 5th Support provided Ischemic Heart Infections: A Hot Floor by Bracco Disease Topic Diagnostics Inc. Chicago Ballroom D, Chicago (Bonus Loop Card 5th Floor Ballroom G, 5th point) Floor

LEARNING LEVELS Core Intermediate Advanced Expert *Schedule is subject to change.

12 www.asnc.org/ASNC2019 SATURDAY, SEPTEMBER 14 3:30 pm – Posters – 7th Floor Foyer 4:30 pm ePosters – North Alcove, 7th Floor Expo Hall Break and Prize Drawing Expo Hall, 7th Floor Technology and Techniques Stress Testing for the Technologists Belmont, 4th Floor Social Media Benefits of Being Engaged in Social Media: What Can SoMe Do for Me? Chicago Ballroom F, 5th Floor 4:30 pm – Advanced Image- Cases with the Aces PET 6:00 pm Predicting the Future: Based Case Focus on Myocardial Blood Flow: Debates in Cardiac PET: Clash of the Machine Learning Management Cases from MidAmerica Heart Photons and Big Data in The “I’s” Have Armitage, 4th Floor Chicago Ballroom E, 5th Floor Cardiac Imaging It: Advanced Chicago Ballroom D, PET Imaging for 5th Floor Inflammation, Infection, and Infiltration Chicago Ballroom G, 5th Floor

4:00 pm – Sail and Learn - Architecture Boat Tour 7:00 pm Appropriate Use Criteria: Incorporating the AUC into Your Practice Meet in Chicago Ballroom H, 5th Floor. Boat Tour starts at 5:30 pm 6:15 pm – Evening Workshop: Coronary Physiology To Guide CAD Management - 7:30 pm Measurements, Meaning and Mortality (Non-CME) Sponsored by Bracco Diagnostics Inc. Marriott Ballroom, 4th Floor (Bonus Loop Card apple gift card drawings)

SUNDAY, SEPTEMBER 15 8:00 am – Plenary 9:30 am Mindful Myocardium: Imaging to Delineate the Brain-Heart Continuum Chicago Ballroom D, 5th Floor 9:45 am – Intersocietal Multimodality PET Team-Based Learning 11:15 am Imaging Myocardial Perfusion by PET Optimize Your Nuclear Lab to Exceed Your Heart Failure of Unknown Etiology: Chicago Ballroom F, 5th Floor Ex-SPECT-ations! What to Know After the Echo? Chicago Ballroom G, 5th Floor Chicago Ballroom E, 5th Floor 11:30 am – PET Team-Based Learning 12:45 pm Perfecting the Performance of PET in A Day in the Life of a Nuclear Cardiology Laboratory Your Practice Chicago Ballroom F, 5th Floor Chicago Ballroom E, 5th Floor

LEARNING LEVELS Core Intermediate Advanced Expert *Schedule is subject to change.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 13 INDUSTRY SPONSORED SATELLITE SYMPOSIA

FRIDAY, SEPTEMBER 13, 2019 FRIDAY BREAKFAST WORKSHOP FRIDAY LUNCH & LEARN FRIDAY PET SATELLITE SESSION 6:30 am – 7:45 am 12:15 pm – 1:30 pm 6:15 pm – 8:00 pm Marriott Ballroom, 4th Floor Marriott Ballroom, 4th Floor Marriott Ballroom, 4th Floor HEREDITARY AMYLOID PRACTICAL CONSIDERATIONS FOR THE TIME IS NOW: WHY CARDIAC TRANSTHYRETIN (hATTR) STARTING A PET PROGRAM PET AND ITS VALUE FOR YOUR AMYLOIDOSIS: A CLINICAL Rupa Mehta Sanghani, MD, PRACTICE DIAGNOSTIC APPROACH FASNC Part I – Cardiac PET: Why and How David G. Wolinsky, MD, Associate Professor, Rush Moderator: Rami Doukky, MD, FASNC MASNC Medical College Section Head Nuclear Director of Nuclear Part II – Interpreting Cardiac PET and Cardiology Cardiology and Stress Laboratory Cardiac PET/CT Medical Director Cardiac Associate Director, Rush Heart Moderator: Rob S.B. Beanlands, MD, FASNC Rehabilitation Center for Women Cleveland Clinic Florida Rush University Medical Center Sponsored by Weston, FL Chicago, IL

Sponsored by

14 www.asnc.org/ASNC2019 Support the IANC Research Fellowship Award and Score Some ASNC Swag!

Support the ASNC Institute for the Advancement of Nuclear cardiac imaging has been proven Nuclear Cardiology (IANC) Research Fellowship Award, to be a clinically effective approach in the created to support promising young researchers in the field diagnosis and prognosis of cardiovascular of nuclear cardiology by donating to the IANC today. Visit disease. A rich foundation of scientific the ASNC Booth in the Expo Hall Foyer (7th Floor) to make evidence set the stage to demonstrate the a donation and get some ASNC Swag! Donations are 100% value and role of nuclear cardiac image in a value-based tax deductible. health care system. ASNC has taken and will continue to take a leadership role in developing and expanding the Thanks to the generosity of ASNC donors, the first IANC field. With the future in mind, ASNC has established the Research Fellowship Grant ($50,000) was awarded at Institute for the Advancement of Nuclear Cardiology (IANC) ASNC2018 to Krishna Patel, MD, to fund her project, to enhance growth and innovation of nuclear cardiology “Patient-centered Reporting in Myocardial Perfusion and its professionals and patients. The IANC will provide Imaging: Development and Pilot-testing a Framework for a framework that will drive continued innovation and Incorporating Patient-centered Decision Support in MPI commitment to the field. Reports.” ASNC is thrilled to support young researchers working on innovative projects and look forward to Dr. Patel’s continued success. Your donation will help ASNC You may also make your donation at continue to enable our future leaders to advance the field www.asnc.org/asncfund of nuclear cardiology.

Join us for the ASNC2019 Cocktail Reception Friday, September 13, 8:30 PM Rooftop of The Gwen Hotel 521 N Rush St Chicago, IL 60611

Featuring the Thallium Stallions Visit Booth #605 to pick up your bracelet for admission and drink tickets.

Sponsored by John J. Mahmarian, MD, ASNC LEADERSHIP AWARD MASNC 18th Annual Mario Verani Rob S. B. Beanlands, MD, Memorial Lecture FASNC A Tale of Two Imaging University of Ottawa Technologies: Can Heart Institute Nuclear Cardiology Survive the Emergence of Cardiac CT?

2019 AWARDEES

Senthil Selvaraj, MD Kenneth Nichols, PhD Carole de Vaugelade, MD 2019 ASNC/IANC Zaret-Beller Journal of Journal of Nuclear Research Award - Nuclear Cardiology Cardiology Comparison of the Distinguished Service Raymond J. Gibbons Short-Term Effect of Award for Best Reviewer Best Basic Research Paper Dietary Carbohydrate Award Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Catherine Gebhard, MD, Ran Klein, PhD Suppression and Timing to Achieve a PhD Journal of Nuclear State of Ketosis Using Serial Imaging on Journal of Nuclear Cardiology a State-of-the Art Total-Body PET System Cardiology H. William Strauss Ken Brown Best Technical Research Award for Best Editorial Paper Saurabh Malhotra, MD, MPH, FASNC Journal of Nuclear Cardiology Frans J. Th. Wackers Best Clinical Research Paper Award 2019 DISTINGUISHED SERVICE AWARD

Jeroen Bax, MD, PhD, K. Lance Gould, MD FASNC McGovern Medical School Universiteit Leiden at The University of Texas Health Science Center at Houston

2019 MASNCs

Jeroen Bax, MD, PhD James Case, PhD K. Lance Gould, MD Universiteit Leiden Cardiovascular Imaging McGovern Medical School Technologies at The University of Texas Health Science Center at Houston

Rob S. B. Beanlands, MD Marcelo Di Carli, MD Rory Hachamovitch, MD University of Ottawa Heart Brigham and Women’s Cleveland Clinic Institute Hospital

2019 FASNCs

Osama Alsara, MD Steven Raible, MD Abdulbaset Sulaiman, MD Carle Foundation Hospital Norton Healthcare Heart Hospital, Doha, Qatar

Lisa Pudusseri, DO Terrence Ruddy, MD Jean-Luc Urbain, MD, PhD, CPE Cardiovascular Consultants University of Ottawa Heart Institute Wake Forest University Advocate Christ Hospital Little Company of Mary Hospital Palos Bartolo Santiago-Delgado, MD Community Hospital VA Caribbean Healthcare System Centro Cardiovascular de Puerto Rico y del Caribe 2019 LDP GRADUATES

Paul Cremer, MD Nishant Shah, MD, MPH, FASNC Richard Weinberg, MD, FASNC Cleveland Clinic Alpert Medical School of Brown University of Michigan Health System University

16 www.asnc.org/ASNC2019 #ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 17 THURSDAY,ASNC SEPTEMBER EDUCATION 12

TUESDAY, SEPTEMBER 10

4:00 PM – 7:00 PM Registration Location: 5th Floor Registration

WEDNESDAY, SEPTEMBER 11

6:00 AM – 7:00 PM Registration Location: 5th Floor Registration

6:30 AM – 6:00 PM Board Exam Preparation Course Location: Chicago Ballroom D, 5th Floor Separate registration

THURSDAY, SEPTEMBER 12

6:00 AM – 7:00 PM Registration Location: 7th Floor Registration

6:30 AM – 4:30 PM Board Exam Preparation Course Location: Chicago Ballroom D, 5th Floor Separate registration

10:00 AM – 6:00 PM Speaker Ready Room Location: Denver, 5th Floor

12:00 PM – 1:00 PM

Plenary PL–01. Opening Keynote Location: Marriott Ballroom, 4th Floor CME/MOC: 1.0; CE: 1.0 12:00 PM Introduction Panithaya Chareonthaitawee, MD 12:05 PM Addressing Cardiovascular Disease Disparities – Are We Getting Closer to the Truth? Clyde W. Yancy, MD 12:45 PM Questions and Answers

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 18 ASNC EDUCATION

THURSDAY, SEPTEMBER 12

2:00 PM – 3:30 PM Team–based Learning TB–01. Best Practices for Radiation Reduction Location: Belmont, 4th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Manuel D. Cerqueira, MD, MASNC and Christopher L. Hansen, MD, FASNC 2:00 PM Where Do We Stand with Radiation Reduction in 2019: An Overview Gary V. Heller, MD, PhD, MASNC 2:15 PM What is the Harm to Patients and Staff with Current Radiation Doses? Aiden Abidov, MD, PhD 2:30 PM Reducing Dose with New Camera Technology and Software Ronald G. Schwartz, MD MS, MASNC 2:45 PM Reducing Radiation Dose with Existing Anger Cameras and Software Ernest G. DePuey, MD, MASNC 3:00 PM How to Apply Stress–First or Stress–Only Imaging in the Real World Saurabh Malhotra, MD, MPH, FASNC 3:15 PM Panel Discussion

Image–based Case Management CM–01. Demographics Dictate: Evaluating Ischemia in Special Populations Location: Armitage, 4th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Dennis A. Calnon, MD, MASNC and Mark Travin, MD, MASNC 2:00 PM Women with Chest Pain – Case Presenter Sarah Cuddy, MB, ChB 2:05 PM Women with Chest Pain – Discussant Lawrence M. Phillips, MD, FASNC 2:20 PM Elderly (≥80 years) Patient with Chest Pain – Case Presenter Hayan Jouni, MD 2:25 PM Elderly (≥80 years) Patient with Chest Pain – Discussant Myron C. Gerson, MD, MASNC 2:40 PM Patient with BMI ≥45 and Chest Pain – Case Presenter Ibrahim M. Saeed, MD 2:45 PM Patient with BMI ≥45 and Chest Pain – Discussant W. Lane Duvall, MD, FASNC 3:00 PM Panel Discussion

19 www.asnc.org/ASNC2019 THURSDAY, SEPTEMBER 12

2:00 PM – 4:00 PM Off–site Education Ticketed event Lab–01. Lab Visit: Cardiac PET Program at Rush: How to Start a PET Program: Practical First Steps Location: Rush University – PET Lab Rush Lab visit shuttle sponsored by Siemens Healthineers CME/MOC: 2.0; CE: 0 1:15 PM Meet at 7th Floor Registration 1:30 PM Shuttle departs from Chicago Marriott Downtown Magnificent Mile 2:00 PM Speakers Rupa Mehta Sanghani, MD, FASNC; Rami Doukky, MD, FASNC; and Mouaz H. Al-Mallah, MD, MSc, FASNC Break into two groups: Visit the PET imaging room and discuss how to get started 3:00 PM Both groups review cases, technical pitfalls, and lessons learned the hard way 3:30 PM Questions and Answers

3:45 PM – 5:00 PM Intersocietal Multimodality Imaging IM–01. Imaging for CAD: Which Test is Best for Pain in the Chest? Location: Armitage, 4th Floor CME/MOC: 1.25; CE: 1.25 Moderators: Daniel S. Berman, MD, MASNC and George A. Beller, MD, MASNC 3:45 PM Anatomy Versus Ischemia Testing Manuel D. Cerqueira, MD, MASNC 4:05 PM Choosing Best Test for Suspected CAD: Pros and Cons of NICE Guidelines Raymond J. Gibbons, MD, MASNC 4:25 PM Novel Applications of Sodium Fluoride in Vascular and Valvular Disease Mehran Sadeghi, MD 4:45 PM Case Presentations Ahmed Aljizeeri, MB BS, FASNC

Policy POL-01. Overview: ASNC and Reimbursement Advocacy Location: Belmont, 4th Floor CME/MOC: 1.25; CE: 1.25 Moderators: Robert C. Hendel MD, MASNC, April Mann, MBA, CNMT, RT(N), NCT, MASNC and David G. Wolinsky, MD, MASNC 3:45 PM Overview David G. Wolinsky, MD, MASNC 4:05 PM Role of AMA RUC and Medical Societies William A. Van Decker, MD, MASNC 4:25 PM Proposed Medicare Reimbursement for 2020 Denise A. Merlino, CPC, MBA, CNMT

Ticketed session.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 20 ASNC EDUCATION

THURSDAY, SEPTEMBER 12

5:15 PM – 6:30 PM Plenary PL–02. President’s Session and Mario Verani Lecture Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.0; CE: 1.0 Welcome and Introduction of ASNC President Kathleen B. Flood, CEO, American Society of Nuclear Cardiology ASNC President’s Welcome and Introduction of Program Chair Rob S.B Beanlands, MD, FASNC ASNC2019 Program Overview Panithaya Chareonthaitawee, MD Recognition Rob S.B Beanlands, MD, FASNC ASNC President’s Address Rob S.B Beanlands, MD, FASNC Presentation of Leadership Award Sharmila Dorbala, MD, MPH, FASNC President Elect’s Address Sharmila Dorbala, MD, MPH, FASNC Introduction of Mario Verani Lecturer Manuel D. Cerqueira, MD, MASNC Mario Verani Keynote Lecture – A Tale of Two Imaging Technologies: Can Nuclear Cardiology Survive the Emergence of Cardiac CT? John J. Mahmarian, MD, MASNC

6:30 PM – 7:45 PM Welcome Reception and Opening of the ASNC2019 Expo Hall Location: Expo Hall, 7th Floor

21 www.asnc.org/ASNC2019 THURSDAY, SEPTEMBER 12

6:45 PM – 7:45 PM 100. Rapid Fire ePosters Location: South Alcove, 7th Floor Poster Discussants: Diwaker Jain, MD, MASNC and Matthew E. Harinstein, MD, FASNC CME/MOC: 0.75; CE: 0

6:45 PM 100–01 Appropriateness of Inpatient Stress Testing: S. Divakaran*,1 A. Singh,2 E. M. DeFilippis,3 T. Implications for Development of Future Clinical W. Churchill,4 V. R. Taqueti,1 S. Dorbala,1 J. Decision Support Mechanisms and Criteria Spalding,5 Y. Xu,5 M. F. Di Carli,6 M. A. Yialamas,6 R. Blankstein7; 1Brigham and Women’s Hospital, Boston, MA, 2Cardiac Amyloidosis Program, Brigham and Women’s Hospital, Boston, MA, 3New York Presbyterian–Columbia University Irving Medical Center, New York, NY, 4Massachusetts General Hospital, Boston, MA, 5Astellas Pharma Global Development, Northbrook, IL, 6Brigham & Women’s Hospital, Boston, MA, 7Brigham & Women’s Hospital, Boston, MA 6:55 PM 100–02 Comparison of Sympathetic Innervation Status S. Cho*,1 J. Cho,2 J. Kim,3 H. Song3; 1Chonnam National Between HFrEF a HFrecEF: A Pilot Cross– University Hospital, Gwang–ju, Korea, Republic sectional Study of, 2Department of Cardiovascular Medicine, Chonnam National University Hospital, Gwangju, Korea, Republic of, 3Chonnam National University Hospital, Gwangju, Korea, Republic of 7:05 PM 100–03 99mTechnetium Pyrophosphate SPECT Improves T. Asif*,1 T. Araujo,2 J. Gomez Valencia,1 V. Singh,3 R. Diagnostic Certainty Of Transthyretin Cardiac Doukky,4 S. Malhotra5; 1Cook County Hospital, Amyloidosis: A Multicenter Experience From Chicago, IL, 2Medicine, Cook County Health System, Underserved Populations Chicago, IL, 3Brigham & Women’s Hospital, Boston, MA, 4Cardiology, Cook County Health and Hospitals System, Chicago, IL, 5Cook County Health System, Chicago, IL 7:15 PM 100–04 Evaluation Of Quantitative CMR Perfusion T. Kero,1 E. Johansson,2 M. Engström,3 J. Sörensen,1 M. Imaging By Comparison With Simultaneous 15O– Lubberink*1; 1Uppsala University, Uppsala, water–PET Sweden, 2Antaros Medical AB, Gothenburg, Sweden, 3GE Healthcare, Stockholm, Sweden 7:25 PM 100–05 Heart Score Does Not Predict An Abnormal C. Sadeghi*,1 M. Nagahama,1 A. Ogunsakin,1 S. Myocardial Perfusion SPECT Among Patients Kattel,1 R. Karki,1 S. Fernandez,1 S. Presenting To The Emergency Department With Malhotra2; 1University at Buffalo, Buffalo, NY, 2Stroger Chest Pain Hospital of Cook County and Rush Medical College, Chicago, IL 7:35 PM 100–06 Utilization Of Coronary Ct Angiography M. Piccinelli*,1 D. Cooke,2 R. Folks,3 E. V. Garcia4; 1Emory Templates For The 4d Visualization Of MPI– University, Atlanta, GA, 2EUH / Radiology, Emory derived LV Myocardial Thickening University, Atlanta, GA, 3Emory University, STONE MOUNTAIN, GA, 4Radiology, Emory University Hospital, Atlanta, GA

*Denotes presenting author.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 22 ASNC EDUCATION

THURSDAY, SEPTEMBER 12

101. ePoster Session I: PET Myocardial Blood Flow Location: North Alcove, 7th Floor Poster Discussant: Marcelo DiCarli, MD, FASNC CME/MOC: 1.0; CE: 0

6:50 PM 101–01 Evaluation Of Myocardial Extraction Fraction S. Thorn*,1 Y. Huang,1 D. Labaree,1 N. Nabulsi,1 P. With Variable Pharmacological Vasodilation For Emery,1 Z. Felchner,1 S. Lee,1R. Avendano,1 C. A Novel Pet Myocardial Perfusion Tracer, 18F– Hawley,1 M. Mamarian,1 T. Treves,2 J. Inkster,2 A. Rho6G Packard,2 A. J. Sinusas1; 1Yale University School of Medicine, New Haven, CT, 2Boston Children’s Hospital, Boston, MA 7:00 PM 101–02 Differential Association Of Diabetes Mellitus K. Wu*, R. McPhedran, N. Timmerman, R. S. And Impaired 82Rb Pet Hyperemic Myocardial Beanlands, R. A. deKemp, A. Chong; University of Blood Flow Across The Spectrum Of Epicardial Ottawa Heart Institute, Ottawa, ON, Canada Coronary Disease 7:10 PM 101–03 Myocardial Flow Reserve From Rubidium–82 C. Gallegos*,1 C. Trejo–Paredes,1 E. Posada,1 Y. Positron Emission Tomography Correlates With Saito,1 Y. Liu,1 B. D. Young,2 E. Spatz,1 E. J. Miller3; 1Yale Coronary Artery Lesion Characteristics And School of Medicine, New Haven, CT, 2Internal Predicts Severity Of Coronary Artery Obstruction Medicine, Yale University School of Medicine, New Haven, CT, 3Yale University, New Haven, CT 7:20 PM 101–04 Effect Of Measurement Uncertainty On Coronary J. B. Moody*,1 A. Poitrasson–Rivière,1 T. Hagio,2 J. Flow Capacity Interpretation Tang,3 R. Weinberg,4 J. R. Corbett,5 V. L. Murthy,6 E. P. Ficaro7; 1INVIA, LLC, Ann Arbor, MI, 2INVIA, Ann Arbor, MI, 3Oakland University, Rochester, MI, 4Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, 5Radiology, University of Michigan, Ann Arbor, MI, 6Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 7University of Michigan Health System, Ann Arbor, MI 7:30 PM 101–05 Analysis Of Time Activity Curves From Two T. Hagio*,1 A. Poitrasson–Rivière,1 J. B. Moody,1 J. Different 82Rubidium Generators R. Corbett,2 R. Weinberg,3 V. L. Murthy,4 E. P. Ficaro1; 1INVIA, Ann Arbor, MI, 2Radiology, University of Michigan, Ann Arbor, MI, 3Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, 4Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI

*Denotes presenting author.

23 www.asnc.org/ASNC2019 THURSDAY, SEPTEMBER 12

102. Poster Session I: National and International Perspectives in Cardiac Imaging Location: 7th Floor Foyer on Sep 12 2019 Poster Discussants: Erick Alexanderson, MD and Dennis A. Calnon, MD, MASNC CME/MOC: 1.0; CE: 0 102-01 Considerations In The Guideline Based Z. Huang, T. Chua, F. Keng*; NHCS, Singapore, Singapore Application Of Obstructive Cad Prediction Model To Select Patients For SPECT Myocardial Perfusion Imaging 102-02 The Use of MUGA in Predicting Right Ventricular V. N. Patel*,1 M. C. Tam,1 M. Palardy,1 M. C. Konerman,1 V. Failure Post Left Ventricular Assist Device L. Murthy2; 1University of Michigan, Ann Arbor, MI, 2Frankel Implantation Cardiovascular Center, University of Michigan, Ann Arbor, MI 102-03 Description Of Effective Radiation Dose Of V. Gomez*,1 A. PUENTE,2 C. Martinez,3 L. Estrada,3 J. Cuero4; Patients After Myocardial Perfusion Studies In A 12Cardiology, Centro Medico Nacional 20 de Noviembre Mexican National Concentration Center. ISSSTE, Mexico, Mexico, 3ISSSTE National Medical Center “20 de Noviembre”, Mexico City, Mexico, 4IMSS Western National Medical Center, Guadalajara, Mexico 102-04 99mTc-labeled RBC-ERNA Study As An Indirect S. K. Vadi*,1 B. R. Mittal,2 A. Sood,3 A. Khadwal,4 M. Parmar,5 Biomarker For Hepatic Iron Overload In Beta K. Kaur,5 A. Bhatia,6 A. Bahl7; 1Post Graduate Institute of Thalassemia Major Patients: Looking Beyond Medical Education and Research, Chandigarh, India, 2Nuclear The Heart -a Pilot Study. Medicine & PET, Postgraduate Institute of Medical Education and Research, Chandigarh, India, 3Nuclear Medicine, PGIMER, Chandigarh, India, 4Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India, 5Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India, 6Department of Radiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India, 7Department of Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India 102-05 Safety And Tolerability Of Regadenoson In P. Z. Stavrou*,1 K. Polytarchou,1 C. Giannopoulou,1 K. Pantos,2 I. Myocardial Perfusion Imaging: A Randomized Mourouzis,2 I. Datseris,1 A. S. Manolis2; 1Evaggelismo General Controlled Study With Dipyridamole Of Patients Hospital, Athens, Greece, 2Athens University School of Medicine, Referred For Pre-operative Evaluation. Athens, Greece 102-06 Heart Score Stratifies The Risk Coronary Artery M. Nagahama*,1 A. Bhardwaj,2 S. Malhotra3; 1University at Disease On Sequential Testing Among Patients Buffalo, Buffalo, NY, 2Rutgers New Jersey Medical School, With Significant Anatomical Disease On Cardiac Newark, NJ, 3Stroger Hospital of Cook County and Rush Computed Tomography Angiography Medical College, Chicago, IL 102-07 Comparison Of Equilibrium Radionuclide K. Chen*,1 N. E. Boutagy,2 A. Feher,3 J. Stendahl,4 C. Liu,5 A. J. Angiocardiography, Echocardiography And Cine Sinusas6; 1Yale University, New Haven, CT, 2Internal Medicine CT For Early Detection Of Doxorubicin-induced (Cardiology), Yale University, New Haven, CT, 3Yale University Cardiotoxicity School of Medicine, Hamden, CT, 4Cardiology, Yale University, New Haven, CT, 5Yale PET Center, New Haven, CT, 6Yale University School of Medicine, New Haven, CT 102-08 Care Pathways And Outcomes For Patients K. Ananthasubramaniam*,1 T. Kitt,2 A. Saxena,3 Q. Feng,3 D. Undergoing Noninvasive Testing For Coronary Nimke,3 J. Spalding,2 Y. Xu2; 1Henry Ford Hospital, Detroit, Disease: A Cohort Study Comparing Outpatient MI, 2Astellas Pharma Global Development, Northbrook, IL, To Emergency Room Visits 3Astellas US LLC, Northbrook, IL

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 24 ASNC EDUCATION

THURSDAY, SEPTEMBER 12

102-09 Missed Opportunities In Primary And Secondary J. L. Meadows*,1 Y. Johnson,2 S. Mattei,2 M. Burg,1 B. Malm,1 Prevention In Patients Referred To Nuclear R. Soufer1; 1Yale School of Medicine, New Haven, CT, 2VHA- Cardiology Connecticut, West Haven, CT 102-10 The Impact Of Coronary Artery Calcium Scoring G. Pershwitz*,1 K. Balakumaran,2 S. Joshi,2 W. Chaudhry,1 On Insurance Approval For PCSK9 Inhibitor W. Duvall3; 1Hartford Hospital, Hartford, CT, 2University Therapy of Connecticut Medical Center, Farmington, CT, 3Nuclear Cardiology, Hartford Hospital, Hartford, CT 102-11 Patient Utilities For Test Results And The E. Rrapo Kaso*,1 J. M. Bourque2; 1University of Virginia Medical Relationship Of Symptom Burden And Center, Charlottesville, VA, 2University of Virginia Health Functional Status In Evaluation Of Suspected Systems, Crozet, VA Coronary Artery Disease: Facilitating A Shared Decision-making Approach 102-12 Inattentional Blindness During Interpretation of D. E. Winchester*, M. M. Kates, R. J. Beyth; University of Florida, Imaging Reports Gainesville, FL 102-13 99mTc-labeled RBC ERNA As An Adjunct A. Sood*,1 S. K. Vadi,1 B. R. Mittal,2 A. Khadwal,3 M. Parmar,1 Imaging Biomarker For Marrow Hyperplasia In K. Kaur,1 A. Bhatia,1 A. Bahl1; 1PGIMER, Chandigarh, India, Thalassemia Major Patients -a Prospective Case 2Nuclear Medicine & PET, Postgraduate Institute of Medical Control Study Education and Research, Chandigarh, India, 3Department of Internal Medicine, PGIMER, Chandigarh, India 102-14 Provider Level Interpretation Heterogeneity A. Small*, W. Schulz, H. Krumholz, E Impacts Myocardial Perfusion Imaging Reporting

*Denotes presenting author.

FRIDAY, SEPTEMBER 13

6:30 AM – 7:45 AM Satellite Session SAT–02. Breakfast Workshop (non–CME) Hereditary Amyloid Transthyretin (hATTR) Amyloidosis: A Clinical Diagnostic Approach David G. Wolinsky, MD, MASNC Section Head Nuclear Cardiology Medical Director, Cardiac Rehabilitation Cleveland Clinic Florida Sponsored by Akcea Therapeutics Location: Marriott Ballroom, 4th Floor

7:00 AM - 7:00 PM Registration Location: 7th Floor Registration

7:00 AM - 5:00 PM Speaker Ready Room Location: Denver, 5th Floor

25 www.asnc.org/ASNC2019 FRIDAY, SEPTEMBER 13

7:45 am - 8:00 am ASNC/ACC: Our Societies Working for You Location: Chicago Ballroom D, 5th Floor 7:45 AM 2019 ASNC President Rob S.B. Beanlands, MD, FASNC President-Elect of the American College of Cardiology Athena Poppas, MD Distinguished Service Award Pamela S. Douglas, MD Ursula Geller Professor for Research in Cardiovascular Disease Duke University School of Medicine Director, Multimodality Imaging Program, Duke Clinical Research Institute Distinguished Service Award – In Memoriam William D. Nelligan, III, CAE, FACC, MASNC

8:05 AM - 9:30 AM Plenary PL-03. Quantitative Perfusion Imaging: Time to Go with the Flow Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Marcelo Di Carli, MD and Thomas H. Schindler, MD 8:05 AM Practical Aspects of PET Quantitative Myocardial Blood Flow Robert A. deKemp, PhD 8:25 AM How is PET Quantitative Myocardial Blood Flow Different from FFR Nils P. Johnson, MD 8:45 AM Quantitative Myocardial Blood Flow with SPECT James A. Case, PhD 9:05 AM Clinical Applications: Cases Indu Poornima, MD, FASNC 9:25 AM Panel Discussion

8:30 AM – 4:30 PM Expo Hall Hours Location: Expo Hall, 7th Floor 9:30 AM Coffee Break 12:30 PM Expo Hall closed for Lunch and Learn 1:15 PM Expo Hall open 1:30 PM Dessert Reception and Prize Drawing 3:30 PM Cases Over Cocktails in the Expo Hall Sponsored by Alnylam Pharmaceuticals

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 26 ASNC EDUCATION

FRIDAY, SEPTEMBER 13

9:30 AM – 10:00 AM ASNC Awards and Recognition Ceremony Location: Chicago Ballroom D, 5th Floor Presentation of 2019 ASNC/IANC Research Fellowship Award to Dr. Senthil Selvaraj Rob S.B. Beanlands, MD, FASNC 2019 ASNC/IANC Research Award – Comparison of the Short–Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using Serial Imaging on a State–of–the Art Total–Body PET System Senthil Selvaraj, MD Pfizer Young Investigator Award Sharmila Dorbala, MD, MPH, FASNC Recognition of the Outgoing Executive Committee, Board Members and the Strategic Organizing Committee Chair Rob S.B Beanlands, MD, FASNC Recognition of the Leadership Development Program Prem Soman, MD, PhD, MASNC FASNC Recognition Rob S.B Beanlands, MD, FASNC MASNC Recognition and Distinguished Service Award Prem Soman, MD, PhD, MASNC Journal of Nuclear Cardiology Awards Ami E. Iskandrian, MD, PhD, MASNC 2019 Zaret Beller JNC Distinguished Service Award for Best Reviewer – Kenneth J. Nichols, PhD Ami E. Iskandrian, MD, PhD, MASNC 2019 Raymond J. Gibbons Basic Research Paper Award – Carole de Vaugelade, MD Ami E. Iskandrian, MD, PhD, MASNC 2019 H. William Strauss Best Technical Research Paper Award – Ran Klein, PhD Ami E. Iskandrian, MD, PhD, MASNC 2019 Frans J. Th. Wackers Best Clinical Research Paper Award – Saurabh Malhotra, MD, MPH, FASNC Ami E. Iskandrian, MD, PhD, MASNC 2019 Ken Brown Award for Best Editorial – Catherine Gebhard, MD, PhD Ami E. Iskandrian, MD, PhD, MASNC

9:30 AM – 10:30 AM Technology & Techniques TT–01. How to Recognize and Troubleshoot Imaging Artifacts Location: Belmont, 4th Floor CME/MOC: 1.0; CE: 1.0 Moderators: Karthikeyan Ananthasubramaniam, MD, FASNC and Maria G. Sciammarella, MD 9:30 AM SPECT Danny A. Basso, CNMT, NCT 9:50 AM PET/CT Mark C. Hyun, CNMT, NCT, RT(N)(R), FASNC 10:10 AM Incidental Findings Robert A. Pagnanelli, CNMT, RT(N)(R), NCT, FASNC

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201. ePoster Session II: New SPECT Technologies Location: North Alcove, 7th Floor Poster Discussant: Lawrence M. Phillips, MD, FASNC CME/MOC: 1.0; CE: 0 201–03 9:35 AM Quantitative Assessment Of Attenuation M. C. Hyun*,1 S. W. Hayes,1 E. Eisenberg,2 B. K. Corrected Vs Two View Supine/prone Tamarappoo,3 L. E. J. Thomson,1 J. D. Friedman,1 D. S. Acquisitions With Stress Single Photon Emission Berman1; 1Cedars–Sinai Medical Center, Los Angeles, Computed Tomography Myocardial Perfusion CA, 2Cardiac Imaging, Cedars–Sinai Medical Center, Imaging: Correlation With Expert Visual Los Angeles, CA, 3Imaging, Cedars Sinai Medical Interpretation Center, Los Angeles, CA 201–01 9:45 AM Comparison of 3D and 2D SPECT Convolutional B. C. Lee*,1 L. Baskaran,1 A. R. van Rosendael,1 G. Neural Networks for Per–Patient Detection Maliakal,1 G. Singh,1 M. Pandey,1 Z. Xu,1 W. of Abnormal Perfusion: The Multicenter Stuijfzand,1 S. J. Al’Aref,1 F. Y. Lin,1 L. J. Shaw,1 J. K. International CREDENCE Trial Min,1 G. S. Thomas2; 1Weill Cornell Medicine, New York, NY, 2MemorialCare, Fountain Valley, CA 201–02 9:55 AM Development and Validation of a SPECT 3D B. C. Lee*,1 L. Baskaran,1 A. R. van Rosendael,1 G. Convolutional Neural Network for Diagnosis Maliakal,1 G. Singh,1 M. Pandey,1 Z. Xu,1 W. of Vascular Territory–Specific Ischemia: The Stuijfzand,1 S. J. Al’Aref,1 F. Y. Lin,1 L. J. Shaw,1 J. K. Multicenter International CREDENCE Trial Min,1 G. S. Thomas2; 1Weill Cornell Medicine, New York, NY, 2MemorialCare, Fountain Valley, CA 201–04 10:05 AM A Novel Method To Detect Excessive Radiotracer A. Sharma*,1 G. Pershwitz,1 T. M. Morneau,2 G. Heald,1 D. At Injection Site During Tc–99m SPECT Pelletier,1 G. Tadeo,1 F. Quevedo,1 W. Duvall3; 1Hartford Myocardial Perfusion Imaging Hospital, Hartford, CT, 2Non–Invasive Cardiology, Hartford Hospital, Hartford, CT, 3Nuclear Cardiology, Hartford Hospital, Hartford, CT 201–05 10:15 AM Heavy Coronary Calcium Burden Measured S. Cho*,1 J. Kim,1 S. Yoo,1 S. Kang,2 S. Kwon,2 H. Song,3 H. By Myocardial Perfusion SPECT/CT Predicts H. Bom4; 1Chonnam National University Hospital, Abnormal Myocardial Perfusion Gwang–ju, Korea, Republic of, 2Chonnam National University Hwasun Hospital, Hwasun–gun, Jeollanam– do, Korea, Republic of, 3Chonnam National University Hospital, Gwangju, Korea, Republic of, 4Nuclear Medicine, CNUHH, Jeonnam, Korea, Republic of

*Denotes presenting author.

202. Poster Session II: Innovations in SPECT Imaging Location: 7th Floor Foyer Poster Discussant: Jamieson M. Bourque, MD, MHS, FASNC CME/MOC: 1.0; CE: 0

202–01 Correlation Between Speckle Tracking S. H. A. Azab*; Faculty of medicine, Alexandria, Egypt Echocardiography And Thallium 201 Scintigraphy In Assessment Of Myocardial Viability 202–02 Is Myocardial Perfusion Imaging Still Useful In A. Khan*,1 I. Agoston2; 1UT Health San Antonio, San Pre–liver Transplant Evaluation? Antonio, TX, 2Medicine, UT Health San Antonio, San Antonio, TX

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202–03 Intermediate–term Outcomes And C. A. Hanson*,1 J. M. Bourque2; University of Virginia Characteristics Of Patients Undergoing Invasive Health System, Charlottesville, VA, 2University of Coronary Angiography Following Positive Stress Virginia Health Systems, Crozet, VA Testing 202–04 Risk Stratification in Patients Undergoing Renal D. Davies*, M. Rodriguez–Porcel; Mayo Clinic, Transplant Rochester, MN 202–05 Do Renal Transplantation Revert Left Ventricular S. K. Vadi*,1 D. Malik,1 A. Sood,2 S. Singh,3 M. Parmar,1 K. Mechanical Dyssynchrony And Remodeling? A Kaur,1 A. Sharma,3 B. R. Mittal4; 1Department of Proof Of Principle Study Based On Gated SPECT Nuclear Medicine, Post Graduate Institute of Medical Myocardial Perfusion Imaging Education and Research, Chandigarh, India,2Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India,3Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India, 4Nuclear Medicine & PET, Post Graduate Institute of Medical Education and Research, Chandigarh, India 202–06 Left Ventricular Systolic And Diastolic C. Wang,1 J. Shi,1 Z. Zhao,1 C. Li,1 H. Tang,2 Z. He,3 D. Dyssynchrony To Predict Cardiac Li,1 W. Zhou*2; 1The First Affiliated Hospital of Nanjing Resynchronization Therapy Response In Heart Medical University, Nanjing, China, 2University of Failure Patients With Dilated Cardiomyopathy Southern Mississippi, Long Beach, MS,3 University of Southern Mississippi, Hattiesburg, MS 202–07 Elevated Right Ventricular Uptake Ratios On B. M. Yuen*,1 N. Chan,2 M. M. Amor,1 B. Kim,1 A. Regadenoson Nuclear Stress Testing as a Auerbach,1 J. N. Makaryus1; 1North Shore University Predictor Of Obstructive Coronary Artery Disease Hospital at Northwell Health, Manhasset, NY, 2Donald and Barbara Zucker School of Medicine at Hofstra/ Northwell, East Garden City, NY

*Denotes presenting author.

9:45 AM – 10:30 AM Coffee Break in the Expo Hall Location: Expo Hall, 7th Floor 10:30 AM – 12:00 PM Intersocietal Multimodality Imaging IM–02. Anomalous Coronary Artery: Detection and Management Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Wael A. Jaber, MD and Amit R. Patel, MD 10:30 AM Clinical Case Presentation: Overview of the Most Common Anomolies Ibrahim M. Saeed, MD 10:50 AM CTA to Identify High Risk Lesions and Features Benjamin Chow, MD, FASNC 11:10 AM Role of Functional Testing Paul Cremer, MD 11:30 AM Role of Invasive Testing William R. Miranda, MD 11:50 AM Case Follow–up and Management Ibrahim M. Saeed, MD

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Social Media SoME–01. Breaking Boundaries: Social Media and Beyond Location: Chicago Ballroom H, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Renee Bullock–Palmer, MD, FASNC and Niti R. Aggarwal, MD, FASNC 10:30 AM What Are the Social Media Platforms Available – Twitter, Facebook, and LinkedIn Parham Eshtehardi, MD 10:45 AM Why Join Social Media? Benefits to You, Your Career and Your Patients Viet Le, PA–C 11:00 AM How to Use Social Media Responsibly – What Are the Pitfalls to Avoid? Annabelle Volgman, MD 11:15 AM Now Let’s Get You Signed Up! Interactive Hands On Session Niti R. Aggarwal, MD, FASNC 11:30 AM Let’s Go Live! Chiara Bucciarelli-Ducci, MD, PhD 11:50 AM Questions and Answers

Advanced A–01. Microvascular Disease: More Than Just a Small Problem Location: Chicago Ballroom E, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: George A. Beller, MD, MASNC and James E. Udelson, MD, MASNC 10:30 AM Patient Case Asim Khan Babar, MD 10:35 AM Patient Interview James E. Udelson, MD, MASNC 10:35 AM Patient Perspective Constance M. Johnson, PhD, RN 10:45 AM Nuclear Techniques: PET MFR Nils P. Johnson, MD 11:05 AM Invasive Techniques: FFR, IMR, Doppler Flow Habib Samady, MD 11:25 AM Treatment/Ongoing Trials Janet Wei, MD 11:45 AM Panel Discussion

Cases with the Aces CA–01. Sarcoid Heart Disease and Inflammation: Cases from Brigham & Women’s Hospital Location: Armitage, 4th Floor CME/MOC: 1.5; CE: 1.5 10:30 AM Case Presenters: Sanjay Divakaran, MD and Ron Blankstein, MD, FASNC

Ticketed session.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 30 ASNC EDUCATION

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Policy POL–02. The Coverage Equation: Emerging Trends in Nuclear Cardiology Location: Chicago Ballroom G, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Prem Soman, MD, PhD, MASNC and Peter Tilkemeier, MD, MASNC 10:30 AM Physician Viewpoint: The Value of Emerging Services Randall C. Thompson, MD, FASNC 10:45 AM Physician Viewpoint: The Value of Emerging Services Sharmila Dorbala, MD, MPH, FASNC 11:00 AM Payer’s Viewpoint: The Assessment and Approval of New Technology and Services Thomas P. Power, MD 11:15 AM Payer’s Viewpoint: The Assessment and Approval of New Technology and Services Julius Torelli, MD 11:30 AM Questions and Answers

12:15 PM – 1:30 PM Satellite Session SAT–03. Lunch and Learn Practical Considerations for Starting a PET program Rupa Mehta Sanghani, MD, FASNC Associate Professor, Rush Medical College Director of Nuclear Cardiology and Stress Laboratory Associate Director, Rush Heart Center for Women Rush University Medical Center Chicago, IL Sponsored by Jubilant Radiopharma Location: Marriott Ballroom, 4th Floor

12:15 PM – 1:45 PM 210. Young Investigator Competition – Basic Science Location: Chicago Ballroom D, 5th Floor Moderator: Piotr J. Slomka, PhD Judges: Robert J. Gropler, MD, MASNC; James A. Case, PhD, FASNC; and Robert A. deKemp, PhD CME/MOC: 1.25; CE: 1.25

12:20 PM 210–01 Feasibility Of Deep Learning To Enhance The H. Liu*, J. Wu, E. Miller, Y. Liu; Yale University, NEW Detection Accuracy Of Myocardial Perfusion HAVEN, CT Abnormality Using Stress–only Imaging Protocol 12:35 PM 210–02 Residual Subtraction For A Rapid 13N–ammonia A. Poitrasson–Rivière*,1 J. B. Moody,1 T. Hagio,1 J. R. Dynamic Acquisition Protocol Corbett,2 R. Weinberg,3 V. L. Murthy,4E. P. Ficaro1; 1INVIA, Ann Arbor, MI, 2Radiology, University of Michigan, Ann Arbor, MI,3Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, 4Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI

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12:50 PM 210–03 Accuracy Of Arterial [18F]–fluorodeoxyglucose J. Toczek*,1 J. Wu,2 A. T. Hillmer,2 J. Han,2 I. Esterlis,2 K. Uptake Quantification; A Kinetic Modeling Study P. Cosgrove,2 C. Liu,2 M. M. Sadeghi1; 1Yale University, School of Medicine & VA CT Healthcare System, New Haven, CT, 2Yale University, School of Medicine, New Haven, CT 1:05 PM 210–04 Novel Macrophage Elastase–targeted Tracers K. B. GONA*,1 J. Toczek,2 M. Salarian,2 P. Boodagh,2 A. For Imaging Vascular Remodeling In Abdominal Golbazi,2 J. Jung,2 G. Kukreja,2 M. M. Sadeghi1; 1Yale Aortic Aneurysm University, School of Medicine & VA Connecticut Healthcare system, New Haven, CT, 2Yale University, School of Medicine, New Haven, CT 1:20 PM 210–05 Development And Validation Of Semi–automatic T. W. Holmes*,1 D. Cooke,2 P. Raggi,3 E. V. Garcia,4 A. CT Coronary Artery Calcification Scoring Pourmorteza5; 1Emory University, Atlanta, Algorithms Integrated For Nuclear Cardiologists’ GA, 2EUH / Radiology, Emory University, Atlanta, During MPI Interpretations GA, 3Mazankowski Alberta Heart Inst., Edmonton, AB, Canada, 4Radiology, Emory University Hospital, Atlanta, GA,5Radiology and imaging sciences, Emory University, Atlanta, GA

1:30 PM – 2:00 PM Dessert Reception and Prize Drawing Location: Expo Hall, 7th Floor

2:00 PM – 3:30 PM Team–based Learning TB–02. Assessing Myocardial Viability and Inflammation Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Gabriel B. Grossman, MD, PhD, FASNC and James E. Udelson, MD, MASNC 2:00 PM When to Refer a Patient for Radionuclide Viability Imaging James E. Udelson, MD, MASNC 2:15 PM Thallium or Nitrate Enhanced Tc–99M for Viability Imaging Prem Soman, MD, PhD, MASNC 2:30 PM When to Refer a Patient for Radionuclide Infection/Inflammation Imaging Richard Weinberg, MD, PhD, FASNC 2:45 PM Dietary Preparation for FDG PET for Myocardial Viability and Cardiac Inflammation/Infection Panithaya Chareonthaitawee, MD 3:00 PM PET Acquisition and Processing of FDG Viability and Inflammation Studies R. Glenn Wells, PhD 3:15 PM Panel Discussion

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 32 ASNC EDUCATION

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Special SPC–02. Ethics in Nuclear Cardiology: Ageism in Referral and Improving the Quality of Informed Consent Location: Chicago Ballroom G, 5th Floor CME/MOC: 1.5; CE: 1.5 Podium Moderator: Andrew J. Einstein, MD, PhD, FASNC Floor Moderators: Gregory S. Thomas, MD, MPH, MASNC and Randall C. Thompson, MD, FASNC Panelists: Stephen A. Bloom, MD, FASNC, Jennifer H. Mieres, MD, MASNC, and Jeffrey A. Leppo, MD, MASNC Ageism in Referral for Nuclear Cardiology Testing: A Growing Paradigm 2:00 PM Clinical Case Presentation Nishant Shah, MD, MPH, FASNC 2:10 PM Panel Discussion 2:25 PM Questions and Answers Improving the Quality of Consent Forms in Nuclear Cardiology: How Can We Better Educate our Patients? 2:40 PM Informed Consent in Medicine: The Data on Consent Form Readability and Patient Satisfaction Andrew J. Einstein, MD, PhD, FASNC 2:50 PM Panel Discussion 3:05 PM New ASNC Initiative: Standardized Informed Consent Material for Common Nuclear Cardiology Tests Nishant Shah, MD, MPH, FASNC 3:15 PM Questions and Answers

Cases with the Aces CA–02. Integrating SPECT, PET and CT Calcium Scoring and CTA: Cases from Houston Methodist Location: Armitage, 4th Floor CME/MOC: 1.5; CE: 1.5 2:00 PM Case Presenters: Mouaz H. Al–Mallah, MD, MSc, FASNC and John J. Mahmarian, MD, MASNC

Advanced A–02. New Radiotracers in the Pipeline Location: Chicago Ballroom E, 5th Floor This session is supported by an educational grant from Pfizer. CME/MOC: 1.5; CE: 1.5 Moderators: Robert C. Hendel, MD, MASNC and George A. Beller, MD, MASNC 2:00 PM Flurpiridaz: Update and Future Directions Timothy M. Bateman, MD, MASNC 2:20 PM PET–based Amyloid Tracers (Florbetapir, NaF) Edward J. Miller, MD, PhD, FASNC

Ticketed session.

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2:40 PM Sympathetic Innervation Imaging: Time to Bid Farewell to mIBG? Jeroen J. Bax, MD, PhD, FASNC 3:00 PM Novel Imaging Agents: F18 Rhodamine and Annexin–V Robert J. Gropler, MD, MASNC 3:20 PM Panel Discussion

3:30 PM – 4:30 PM Satellite Session SAT–04. Cases Over Cocktails hATTR Amyloidosis: The Mixed Phenotype Patient Nithasha Sarswat, MD Director, Cardiac Amyloid Program Advanced Heart Failure, Mechanical Circulatory Support and Transplantation University of Chicago Sponsored by Alnylam Pharmaceuticals Location: Expo Hall, 7th Floor

4:30 PM Expo HAll Closes Location: Expo Hall, 7th Floor

3:30 PM – 4:30 PM 221. ePoster Session III: Inflammation and Infiltrative Imaging Location: North Alcove, 7th Floor Poster Discussant: Edward J. Miller, MD, PhD, FASNC CME/MOC: 1.0; CE: 0

3:35 PM 221–01 The Use Of SPECT Quantification Of 99mTc–PYP S. Saucier*,1 A. Rizkallah,2 S. R. McMahon,3 W. Uptake In Evaluation Of Cardiac Amyloid Duvall4; 1Hartford Hospital, Hartford, CT,2Cardiology, University of Connecticut/Hartford Hospital, Hartford, CT, 3Cardiology, Hartford hospital, Hartford, CT, 4Nuclear Cardiology, Hartford Hospital, Hartford, CT 3:45 PM 221–02 Treatment Of Specific Microvascular R. B. Pavão*, A. V. Badran, M. O. Lima–Filho, G. L. Ischemia In Patients With Chagas Disease Figueiredo, J. R. A. Chierice, A. C. L. Barros–Filho, H. Cardiomyopathy Improves Symptoms And T. Moreira, A. O. Pintya, J. A. Marin–Neto; University Myocardial Perfusion of São Paulo – Ribeirão Preto School of Medicine (FMRP–USP), Ribeirão Preto, Brazil 3:55 PM 221–03 Imaging Characteristics And Arrhythmic S. R. Sigman*, V. Polsani, B. S. Stambler, A. T. Outcomes In Patients With Clinically Suspected Darlington, N. Dhruva; Piedmont Heart Institute, Cardiac Sarcoidosis Undergoing Cardiac PET Atlanta, GA And Cardiac MRI

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 34 ASNC EDUCATION

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4:05 PM 221–04 Reproducibility And Repeatability Of 99mTc– V. Singh*,1 S. Cuddy,1 M. F. Kijewski,2 M. Park,1 V. pyrophosphate Scan Interpretation For R. Taqueti,3 H. Skali,1 R. Blankstein,1R. Falk,1 M. Di Diagnosis Of Transthyretin Cardiac Amyloidosis Carli,3 S. Dorbala3; 1Brigham & Women’s Hospital, Boston, MA,2Radiology, Brigham and Women’s Hospital, Boston, MA, 3Brigham and Women’s Hospital, Boston, MA 4:15 PM 221–05 Prognostic Value Of Tc–99m Pyrophosphate A. Yoruk*,1 M. L. Mackin,2 R. G. Schwartz3; 1The CZT SPECT Imaging In Patients Suspected Of University of Rochester Medical Center, Rochester, Cardiac TTR Amyloidosis NY, 2University of Rochester, Rochester, NY, 3Cardiology and Imaging Sciences, University of Rochester Medical Center, Rochester, NY

*Denotes presenting author.

222. Poster Session III: New Horizons in Cardiovascular Infection and Inflammation Imaging Location: 7th Floor Foyer Poster Discussant: Edward J. Miller, MD, PhD, FASNC CME/MOC: 1.0; CE: 0

222–01 Early Phase Versus Late Phase 99mTc–Pyro- C. Régis*,1 D. Juneau,1 P. Martineau,2 J. Grégoire,3 G. N. phosphate Scintigraphy For The Diagnosis Of Abikhzer,4 F. Harel,3 M. Pelletier–Galarneau3;1Division of Cardiac Amyloidosis Nuclear Medicine, Centre Hospitalier de l’Université de Montréal (CHUM), Montreal, QC, Canada, 2Radiology, De- partment of Radiology, University of Manitoba, Winnipeg, MB, Canada,3Department of Medical Imaging, Montreal Heart Institute, Montreal, QC, Canada, 4Nuclear Medicine, Department of Radiology and Nuclear Medicine, Jewish General Hospital, Montreal, QC, Canada 222–02 FDG PET/CT In Assessing The Association C. Rojulpote*,1 W. Y. Raynor,1 T. Werner,1 A. Alavi2; 1Uni- Between Myocardial Glucose Metabolism And versity of Pennsylvania, Philadelphia, PA,2Radiology, Blood Pressure University of Pennsylvania, Philadelphia, PA 222–03 FDG PET/CT In Assessing Inflammation In The C. Rojulpote*,1 W. Y. Raynor,1 L. Arani,1 T. J. Werner,1 P. Thoracic Aorta Of Lung Cancer Patients And Its Hoilund–Carlsen,2 A. Alavi3; 1University of Pennsylvania, Correlation With Blood Pressure Philadelphia, PA, 2Odense University Hospital, Odense, Denmark, 3Radiology, University of Pennsylvania, Phila- delphia, PA 222–04 Quantitative Evaluation Of Myocardial Tc99m– N. Bhave*,1 S. Virmani,2 J. Singh,1 R. Prasad3; 1Rush Univer- PYP Scintigraphy: Impact Of Different Roi And sity Medical Center, Chicago, IL, 2Radiology, Rush Univer- Sequential Acquisition sity Medical Center, Chicago, IL, 3Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL 222–05 The Use Of Combined CT Attenuation Scans And S. Saucier*,1 T. M. Smith,2 A. Rizkallah,3 W. Duvall,4 S. R. SPECT Imaging In Assessment Of 99mTc–PYP McMahon5; 1Hartford Hospital, Hartford, CT,2Diagnostic Uptake For Evaluation Of Cardiac Amyloid Radiology, Hartford Hospital, Hartford, CT, 3Cardiology, University of Connecticut/Hartford Hospital, Hartford, CT, 4Nuclear Cardiology, Hartford Hospital, Hartford, CT,5Cardiology, Hartford Hospital, Hartford, CT

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222–06 Cardiac Sarcoid Mimicking Arrhyth- D. A. Sivaratnam*,1 M. Lichtenstein,2 P. B. Sparks3; 1The mogenic Right ventricular Dysplasia/ Royal Melbourne Hospital, Melbourne, Australia, 2Nucle- Cardiomyopathy(arvd/c) ar Medicine, The Royal Melbourne Hospital, Melbourne, Australia, 3Cardiology, The Royal Melbourne Hospital, Melbourne, Australia 222–07 Noninvasive Diagnosis Of Cardiac Amyloidosis M. Kostkiewicz*; Jagiellonian University Collegium Medi- Using 99mtc–3,3–diphosphono–1,2–propanodi- cum Hospital John Paul II, Krakow, Poland carboxylic Acid Scintigraphy

*Denotes presenting author.

3:30 PM – 4:30 PM Technology & Techniques TT–02. Practical Considerations for Technologists for Radiation Dose Reduction Location: Belmont, 4th Floor CME/MOC: 1.0; CE: 1.0 Moderators: Danny A. Basso, CNMT, NCT and Diwakar Jain, MD, MASNC 3:30 PM Weight–based Dosing and How Low Can We go? Jaime Warren, CNMT, MBA 3:50 PM How to Do Stress Only Successfully April Mann, MBA, CNMT, RT(N), NCT, MASNC 4:10 PM Strategies to Reduce Staff Exposure with PET/SPECT Samia Massalha, MD

4:30 PM – 6:00 PM Social Media SoME–02. #SoMe Session with the Giants: Controversies with Lifestyle Medicine and Preventive Cardiology Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Audience Moderators: Niti R. Aggarwal, MD, FASNC and Renee Bullock–Palmer, MD, FASNC Moderator: Jeroen J. Bax, MD, PhD, FASNC 4:30 PM Lifestyle Medicine: Which is More Heart Healthy? Mediterranean Diet vs. Vegan Diet Where’s the Evidence? Pro – Vegan Diet Kim A. Williams, Sr., MD, MASNC Pro Mediterranean Diet Regina S. Druz, MD, FASNC Rebuttals Live Vote! Discussion and Twitter Poll

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 36 ASNC EDUCATION

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5:15 PM Should CAC Be Used for CV Screening? • Case 1: Diabetic patient hesitant about statins– Can CAC be a useful tool? Power of -O Case Presentation Javier A. Gomez Valencia, MD Tally of Audience Response Expert Opinion and Evidence–based Approach Ron Blankstein, MD, FASNC • Case 2: Young 40–year Old Asymptomatic Female with No PMHx or Significant Risk Factors Other Than a Strong Family History of Premature Sudden Cardiac Death. Is There a Role for CAC Score? Case Presentation Samia Massalha, MD Tally of Audience Response Expert Opinion and Evidence–based Approach Donna M. Polk, MD, MPH, FASNC

4:30 PM – 6:00 PM Image–based Case Management CM–02. Getting to the Heart of the Matter: Cardiac Amyloidosis Nuclear Scans in Practice Location: Chicago Ballroom E, 5th Floor This session is supported by an educational grant from Pfizer. CME/MOC: 1.5; CE: 1.5 Moderators: Jamieson M. Bourque, MD, MHS, FASNC and Sharmila Dorbala, MD, MPH, FASNC 4:30 PM The Approach of HFpEF – Case Presenter Rafael Lopes, MD, PhD 4:35 PM The Approach of HFpEF – Discussant Omar F. Abouezzeddine, MD, CM, MS 4:55 PM African American Male with LVH but no Hypertension – Case Presenter Raghunandan Dudda Subramanya, MD, FASNC 5:00 PM African American Male with LVH, but No Hypertension – Discussant Sabahat Bokhari, MD, FASNC 5:20 PM Asymptomatic ATTR Gene Carrier – Case Presenter Hein J. Verberne, MD, PhD 5:25 PM Asymptomatic ATTR Gene Carrier – Discussant Frederick L. Ruberg, MD 5:45 PM Panel Discussion

Special SPC–03. Machine Learning in SPECT MPI Applications Location: Chicago Ballroom G, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Ernest V. Garcia, PhD, MASNC and Piotr J. Slomka, PhD 4:30 PM 2018 Research Fellowship Award Winner Presentation Krishna K. Patel, MD 4:50 PM AI–driven Structured Report Generation Ernest V. Garcia, PhD, MASNC

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5:10 PM Machine Learning for Automatic LV Segmentation and Volume Quantification Weihua Zhou, PhD 5:30 PM Machine Learning for Quantitative Diagnosis and Risk Prediction in Nuclear Cardiology Piotr J. Slomka, PhD 5:50 PM Questions and Answers

Cases with the Aces CA–03. PISA to PARIS: Read the European Way: Cases from France and Italy Location: Armitage, 4th Floor CME/MOC: 1.5; CE: 1.5 4:30 PM Case Presenters: Fabien Hyafil, MD, PhD; Danilo Neglia, MD, PhD; and Alessia Gimelli, MD

6:00 PM – 6:45 PM Tweet up Social Beer and Wine Networking Reception for Tweeters and Tweeter Hopefuls Location will be tweeted before the reception. Follow the Social Media Ambassadors on Twitter, so you can recieve the secret hash tag to tweet for admission.

6:15 PM – 8:00 PM Satellite Session SAT–05. The Time is Now: Why Cardiac PET and its Value for Your Practice Sponsored by Bracco Diagnostics Inc, MiE America, Inc., Molecular Imaging Services Inc., and Siemens Healthineers. Location: Marriott Ballroom, 4th Floor 6:00 PM Registration and Refreshments Part I – Cardiac PET: Why and How Moderator – Rami Doukky, MD, FASNC 6:15 PM Value of Cardiac PET in 2019 Dennis Calnon, MD, MASNC 6:30 PM Nuts and Bolts of Establishing a Cardiac PET Program in Practice Gary V. Heller, MD, PhD, MASNC 6:45 PM New 2020 Cardiac PET CPT Codes Kathleen B. Flood and Denise A. Merlino, CPC, MBA, CNMT 7:00 PM Panel Discussion Moderators: Rob S.B. Beanlands, MD, FASNC and Rami Doukky, MD, FASNC Part II – Interpreting Cardiac PET and Cardiac PET/CT Moderator: Rob S.B. Beanlands, MD, FASNC 7:15 PM Interpretation of CT Timothy M. Bateman, MD, MASNC 7:30 PM Integrating Blood Flow with Perfusion Marcelo Di Carli, MD, FASNC 7:45 PM Panel Discussion Moderators: Rob S.B. Beanlands, MD, FASNC and Rami Doukky, MD, FASNC

Ticketed session.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 38 ASNC EDUCATION

SATURDAY, SEPTEMBER 14

6:15 AM – 7:45 AM Satellite Session SAT–06. Breakfast Workshop* A New Era in the Diagnosis and Treatment of ATTR–CM Jamieson M. Bourque, MD, MHS, FASNC University of Virginia Health System Charlottesville, VA Sabahat Bokhari, MD, FASNC Columbia University Medical Center New York–Presbyterian Hospital College of Physicians and Surgeons Columbia University New York, NY Sponsored by Pfizer Rare Disease Location: Marriott Ballroom, 4th Floor *A full, hot breakfast will be served

7:00 AM – 7:00 PM Registration Location: 7th Floor Registration

7:00 AM – 5:00 PM Speaker Ready Room Location: Denver, 5th Floor

8:00 AM – 9:30 AM Plenary PL–04. Amyloidosis Imaging: Bones, Old Dogs and New Tricks This session is supported by an educational grant from Pfizer. Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Prem Soman, MD, PhD, MASNC and Marla C. Kiess, MD 8:00 AM TTR Amyloidosis: The Disease and Approved Treatments Omar F. Abouezzeddine, MD, CM, MS 8:20 AM Bone Scintigraphy for Diagnosis of Cardiac Amyloidosis: ASNC/Multisocietal Consensus Recommendations Sharmila Dorbala, MD, MPH, FASNC 8:40 AM Large Scale Screen Strategies for TTR Amyloidosis Frederick L. Ruberg, MD 9:00 AM Diagnostic and Treatment Options on the Horizon Daniel Lenihan, MD 9:20 AM Panel Discussion

39 www.asnc.org/ASNC2019 SATURDAY, SEPTEMBER 14

8:30 AM – 4:30 PM Expo Hall EXH–04. Expo Hall Hours Location: Expo Hall, 7th Floor 9:30 AM Coffee Break 12:30 PM Expo Hall is closed for Lunch and Learn 1:15 PM Expo Hall reopens 1:30 PM Dessert Reception and Prize Drawing 3:30 PM Expo Hall Break 4:30 PM Expo Hall closed

9:30 AM – 9:45 AM Special SPC–04. ASNC Business Meeting Location: Chicago Ballroom D, 5th Floor

9:30 AM – 10:30 AM Technology & Techniques TT–03. Case–based Cardiac Amyloid PYP Imaging: ASNC Guidelines vs. Institutional Protocols This session is supported by an educational grant from Pfizer. Location: Belmont, 4th Floor CME/MOC: 1.0; CE: 1.0 Moderators: Daniel S. Berman, MD, MASNC and Randall C. Thompson, MD, FASNC 9:30 AM PYP Protocols for Cardiac Amyloid Imaging Eric J. Schockling, CNMT 9:50 AM Live! How to Process Images: A Hands On Presentation Sabahat Bokhari, MD, FASNC 10:10 AM Interpretation of PYP Scans for Cardiac Amyloid Scott D. Jerome, DO, FASNC

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 40 ASNC EDUCATION

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301. ePoster Session IV: PET Perfusion: General Location: North Alcove, 7th Floor Poster Discussant: Thomas H. Schindler, MD CME/MOC: 0.75; CE: 0

301–01 9:35 AM Improved Pet Image Quality With Saline–push Is A. Ahmadi, K. Gardner, R. S. Beanlands, R. A. deKemp*; Associated With Parameters Of Heart Function University of Ottawa Heart Institute, Ottawa, ON, Canada 301–02 9:45 AM First Patient Experience Of 13N–ammonia R. L. Weinberg,1 J. Pieper*,1 V. Patel,1 S. Escolero,1 J. R. Myocardial Perfusion PET/CT Using A Compact Nelson,1 C. K. Shreves,2 N. K. Freiburger,2 D. Hubers,1 J. Production System Rothley,1 A. Poitrasson–Rivière,3 J. G. Oliverio,2 J. R. Corbett,4 E. P. Ficaro,5 V. L. Murthy6;1University of Michigan, Ann Arbor, MI, 2Ionetix Corporation, San Francisco, CA, 3INVIA, Ann Arbor, MI, 4Radiology, University of Michigan, Ann Arbor, MI, 5University of Michigan Health System, Ann Arbor, MI, 6Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI 301–03 9:55 AM Diagnostic And Predictive Value Of LV Mass J. Sörensen*,1 T. Baron,2 M. Lubberink,3 S. Measured With 15O–water PET Rosengren,2 F. A. Flachskampf,2 H. J. Harms4; 1Surgical Sciences–NM & PET, Uppsala University, Uppsala, Sweden, 2Medical Sciences, Uppsala University, Uppsala, Sweden, 3Surgical Sciences – Radiology, Uppsala University, Uppsala, Sweden, 4Clinical Institute, Aarhus University, Aarhus, Sweden 301–04 10:05 AM The Influence Of Aortic Stenosis And Left S. Biswas*, S. Mason, J. Ethington, R. McCubrey, Ventricular Hypertrophy On The Transient S. Knight, D. B. Min, K. Meredith, M. Minder, V. Ischemic Dilatation Ratio In Rubidium–82 Le, J. L. Anderson, J. B. Muhlestein, K. Knowlton; Positron Emission Tomography Imaging Intermountain Heart Institute, Murray, UT 301–05 10:15 AM Hyperemic Response Of Patients With A. Aljizeeri*,1 M. Alali Alfaris,1 D. Ahmed,1 J. Farea,1 A. Advanced Renal Dysfunction And End–stage Elneama,1 I. Suliman,1 A. Ahmed,1 M. Alharthi,1A. Renal Disease During Vasodilator Stress On Alsaileek,1 M. H. Al–Mallah2; 1King Abdulaziz Cardiac Positron Emission Tomography Center, Riyadh, Saudi Arabia, 2Houston Methodist DeBakey, Houston, TX

*Denotes presenting author.

41 www.asnc.org/ASNC2019 SATURDAY, SEPTEMBER 14

302. Poster Session IV: Advances in Myocardial Blood Flow Assessment: PET and SPECT Location: 7th Floor Foyer Poster Discussant: Gregory S. Thomas, MD, MPH, MASNC CME/MOC: 1.0; CE: 0

302–01 Characterization of Myocardial Blood Flow in M. H. Stewart,1 J. Englert,1 N. Polin,1 R. End Stage Renal Disease Patients Bober*2; 1Ochsner Heart & Vascular Institute, New Orleans, LA, 2Cardiology, Ochsner Heart and Vascular, New Orleans, LA 302–02 Feasibility Of Exercise Treadmill 13N–ammonia D. Harland*, D. Mahlum, P. Galazka, S. Port; Advocate Positron Emission Tomography Myocardial Aurora Health Care, Milwaukee, WI Perfusion Imaging Using An Off–site Cyclotron 302–03 Sensitivity Of PET Cardiac Stress Testing To J. A. Kvasic*,1 J. A. Rosenblatt2; 1Maine Medical Center, Detect Myocardial Perfusion Defects In The Portland, ME, 2Maine Health Cardiology, South Setting Of Low Global Flow Reserve Portland, ME 302–04 Dobutamine Vs. Dipyridamole As Assessed By M. H. Stewart*,1 J. Englert,2 N. Polin,2 R. Myocardial Blood Flow Bober3; 1Ochsner Heart & Vascular Institute, New Orleans, LA, 2Ochsner Heart & Vascular, New Orleans, LA,3Cardiology, Ochsner Heart and Vascular, New Orleans, LA 302–05 The Influence Of Aortic Stenosis And Left S. Biswas*, S. Mason, J. Ethington, R. McCubrey, S. Ventricular Hypertrophy On Coronary Flow Knight, D. B. Min, K. Meredith, M. Minder, V. Le, J. L. Reserve In Rubidium–82 Positron Emission Anderson, K. Knowlton; Intermountain Heart Institute, Tomography Imaging Murray, UT 302–06 Myocardial Perfusion Gated SPECT In A. Puente*, V. Gomez, C. Martinez, L. Delgado Espejel; Postmenopausal Women With Suspected Or Centro Medico Nacional 20 de Noviembre ISSSTE, Actual Ischemic Heart Disease: Is It Worth? Mexico, Mexico

*Denotes presenting author.

10:30 AM – 12:00 PM

Cases with the Aces CA–04. A Positron Experience: PET for Ischemia and Hibernation: Cases from the Cleveland Clinic Location: Armitage, 4th Floor CME/MOC: 1.5; CE: 1.5 10:30 AM Case Presenters: Paul Cremer, MD and Wael A. Jaber, MD

Ticketed session.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 42 ASNC EDUCATION

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Intersocietal Multimodality Imaging IM–03. Cardiac Sarcoidosis: When to Investigate and How? Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Rob S.B Beanlands, MD, FASNC and Mehran Sadeghi, MD 10:30 AM What Does the Sarcoid Cardiac Specialist Need from Imaging? John Bois, MD 10:50 AM The Role of MRI in Cardiac Sarcoidosis Ron Blankstein, MD, FASNC 11:10 AM PET/CT (FDG and New Tracers) Edward Hulten, MD, MPH, FASNC 11:30 AM Challenging Case Presentations Hicham Skali, MD

Image–based Case Management CM–03. Friend and Foe: The Relationship of SPECT and CT for Diagnosis of CAD Location: Chicago Ballroom E, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Brian G. Abbott, MD, MASNC and Benjamin Chow, MD, FASNC 10:30 AM Equivocal CT: Role of SPECT MPI Marcelo Di Carli, MD, FASNC 10:50 AM Normal SPECT MPI with Calcium Scoring to Diagnose CAD Khurram Nasir, MD, MPH 11:10 AM Prior Normal SPECT: CTA As First Test in Emergency Department W. Lane Duvall, MD, FASNC 11:30 AM Perspective from an Interventionalist Gary R. Small, MD 11:45 AM Panel Discussion

Policy POL–03. Health Care Policy: Achieving Success in New Paradigms Location: Chicago Ballroom G, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Dennis A. Calnon, MD, MASNC and William A. Van Decker, MD, MASNC 10:30 AM Legislative Update, ASNC Advocacy and Lobbying 101 Camille S. Bonta 10:45 AM 2020 Payment Update and The Quality Payment Program Georgia Lawrence, JD 11:00 AM How Does Advocacy Affect My Practice? David G. Wolinsky, MD, MASNC 11:15 AM ImageGuide Nuclear: How the Registry Impacts the Future of the Nuclear Field Peter Tilkemeier, MD, MASNC and Joe Reyes 11:30 AM Questions and Answers

43 www.asnc.org/ASNC2019 SATURDAY, SEPTEMBER 14

12:15 PM – 1:30 PM SAT–07. Lunch and Learn Location: Marriott Ballroom, 4th Floor Cardiac PET? Jump in, the Water is Fine: Physician and Administrative Experiences · Justification in moving cardiac from SPECT to PET · Avoiding loss of SPECT volumes · Elimination of MIBI from inpatient service · Reduced length of stay and overall impact to the health system Jackson W. Kiser, MD Chief of Nuclear Medicine, Carilion Clinic, Roanoke, VA James Crowley, MHA, CNMT Imaging Services Manager, Nuclear Medicine, PET/CT, and Mobile Services, Carilion Clinic, Roanoke, VA Sponsored by Siemens Healthineers 12:15 PM – 1:45 PM 310. Young Investigator Competition – Clinical Research Location: Chicago Ballroom D, 5th Floor Moderator: Brian G. Abbott, MD, MASNC Judges: Gary V. Heller, MD, PhD, MASNC; James A. Arrighi, MD, MASNC; and Timothy M. Bateman, MD, MASNC CME/MOC: 0.75; CE: 0.75 12:20 PM 310–01 Worldwide Diagnostic Reference Levels For C. B. Hirschfeld*,1 M. Dondi,2 T. Pascual,3 J. Administered Activity In Single–photon Emission Vitola,4 N. Better,5 G. Karthikeyan,6 D. Paez,3A. J. Computed Tomographic Myocardial Perfusion Einstein1; 1Columbia University Medical Center, New Imaging: Results From The IAEA Nuclear York, NY, 2Human Health, International Atomic Energy Cardiology Protocols Study (INCAPS) Agency, Vienna, Austria, 3International Atomic Energy Agency, Vienna, Austria, 4Quanta Diagnostico & Terapia, Curitiba, Brazil, 5Nuclear Medicine, Royal Melbourne Hospital, Parkville, Victoria, Australia, 6All India Institute of Medical Sciences, New Delhi, India 12:35 PM 310–02 Association Of Right–ventricular Myocardial H. J. Harms*,1 S. Rosengren,2 T. S. Clemmensen,3 L. Blood Flow With Diastolic Dysfunction, Right– P. Tolbod,1 J. Sörensen4; 1Aarhus University Hospital, ventricular Pressures And Adverse Events In Aarhus, Denmark, 2Uppsala University Hospital, Uppsala, Cardiac Amyloidosis Sweden,3Cardiology, Aarhus University Hospital, Aarhus N, Denmark, 4Uppsala University, Uppsala, Sweden 12:50 PM 310–03 Elevated Right–Ventricular Blood Flow Is H. J. Harms*,1 V. R. Taqueti,2 W. Zhou,3 S. Divakaran,4 T. Associated With Diastolic Dysfunction And Tran,1 L. B. Campbell,1 C. Bibbo,1R. Blankstein,1 S. Adverse Cardiovascular Events, Including Heart Dorbala,2 J. Sörensen,5 M. Di Carli1; 1Brigham & Women’s Failure With Preserved Ejection Fraction Hospital, Boston, MA, 2Brigham and Women’s Hospital, Boston, MA, 3Radiology, Brigham and Women’s Hospital, Boston, MA, 4Brigham & Women’s Hospital, Boston, MA, 5Uppsala University, Uppsala, Sweden 1:05 PM 310–04 Caffeine Effects On Myocardial Stress Perfusion A. K. Babar*, D. Kitkungvan, K. Gould; McGovern With Regadenoson PET Imaging Medical School, Houston, TX 1:20 PM 310–05 Incremental Value Of Transient Ischemic Dilation N. Borges*,1 K. Paschke,1 A. Schenone,1 J. Hansen,1 P. Identified On Regadenoson Rubidium Positron Cremer,2 S. Harb,1 W. A. Jaber3;1Cleveland Clinic, Emission Tomography (PET) Myocardial Perfusion Cleveland, OH, 2Heart and Vascular Institute, Imaging In Patients With Left Ventricular Cleveland Clinic Foundation, Shaker Heights, Dysfunction To Identify Multivessel Coronary OH, 3Cleveland Clinic Foundation, Cleveland, OH Artery Disease

*Denotes presenting author.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 44 ASNC EDUCATION

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1:30 PM – 2:00 PM Dessert Reception and Prize Drawing Location: Expo Hall, 7th Floor

2:00 PM – 3:30 PM

Image–based Case Management CM–04. Augmenting Relative Perfusion: Management of Complicated Ischemic Heart Disease Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Keiichiro Yoshinaga, MD, PhD, FASNC and Stephen A. Bloom, MD, FASNC 2:00 PM Patient with Heart Failure: Viability Study – Case Presenter Shivda Pandey, MD 2:05 PM Patient with Heart Failure: Viability Study – Discussant Vikas Veeranna, MD 2:20 PM Patient with Balanced Ischemia or Epicardial Disease and MVD: Use of MPR/CFR – Case Presenter Firas Al Badarin, MD, FASNC 2:25 PM Patient with Balanced Ischemia or Epicardial Disease and MVD: Use of MPR/CFR – Discussant Nishant Shah, MD, MPH, FASNC 2:40 PM Patient with Complex CAD: Use of Hybrid PET/SPECT–CT Imaging for Lesion Localization – Case Presenter Paco E. Bravo, MD 2:45 PM Patient with Complex CAD: Use of Hybrid PET/SPECT–CT Imaging for Lesion Localization – Discussant Fabien Hyafil, MD, PhD 3:00 PM Panel Discussion

PET–01. Cardiac PET: More than Just Perfusion Location: Chicago Ballroom E, 5th Floor This session is supported by an educational grant from Pfizer. CME/MOC: 1.5; CE: 1.5 Moderators: Sabahat Bokhari, MD, FASNC and Panithaya Chareonthaitawee, MD 2:00 PM Viability Imaging: PET and Other Modalities Paul Cremer, MD 2:15 PM Cardiac Device Infection Mouaz H. Al–Mallah, MD, MSc, FASNC 2:30 PM Sarcoid: Detection and Monitoring Brett W. Sperry, MD 2:45 PM New PET Tracers for Amyloid Jamieson M. Bourque, MD, MHS, FASNC 3:00 PM Vascular and Valvular Disease and Inflammation Ahmed Tawakol, MD 3:15 PM Panel Discussion

45 www.asnc.org/ASNC2019 SATURDAY, SEPTEMBER 14

Special SPC–05. Choosing Wisely® Challenge (non-CME) Location: Chicago Ballroom F, 5th Floor Sponsored by Bracco Diagnostics Inc. Moderator: David G. Wolinsky, MD, MASNC Committee: Paul Cremer, MD; Wael A. Jaber, MD; Todd D. Miller, MD, MASNC; Renee Bullock–Palmer, MD, FASNC, and; Maria G. Sciammarella, MD 2:00 PM Welcome, Introductory Remarks, and Judging Overview 2:10 PM Choosing Wisely® Challenge Presentation – Impact of a Novel Myocardial Perfusion Imaging Risk Classification Scheme on Referral for Coronary Angiography, Revascularization, and Mortality Anirudh Kumar, MD 2:30 PM Choosing Wisely® Challenge Presentation – Development of a Patient–centered, Cost–Effective Algorithm Utilizing 99mTechnetium–Pyrophosphate Imaging to Diagnose ATTR Cardiac Amyloidosis Benita Philip, DO 2:50 PM Choosing Wisely® Challenge Presentation – Multi–pronged Approach to Optimize Nuclear Cardiology Testing and Improve Safety at Kaiser Permanente, Mid–Atlantic States (Virginia, Maryland, Washington DC) Sudip Saha, MD 3:10 PM Judging and Audience Voting 3:25 PM Presentation of Awards

Intersocietal Multimodality Imaging IM–04. Imaging for Endocarditis and Device Infections: A Hot Topic Location: Chicago Ballroom G, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Fadi G. Hage, MD, MASNC and Kim A. Williams Sr., MD, MASNC 2:00 PM Etiologies and Treatment: What Can Imaging Provide the Infectious Disease Specialist? Maryam Mahmood, MD 2:20 PM PET–FDG/WBC Geoffrey Johnson, MD, PhD 2:40 PM CT/MRI Paul Cremer, MD 3:00 PM Challenging Cases Hein J. Verberne, MD, PhD

Cases with the Aces CA–05. SPECT as a Work Horse for a Nuclear Lab: Perfusion and Amyloid: Cases from the University of Pittsburgh This session is supported by an educational grant from Pfizer. Location: Armitage, 4th Floor CME/MOC: 1.5; CE: 1.5 Case Presenters: Ahmad Masri, MD and Prem Soman, MD, PhD, MASNC

Ticketed session.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 46 ASNC EDUCATION

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3:30 PM – 4:30 PM Expo Hall Break and Prize Drawing Location: Expo Hall, 7th Floor

3:30 PM – 4:30 PM

Social Media SoME–03. Benefits of Being Engaged in Social Media: What Can #SoMe Do for Me? Location: Chicago Ballroom F, 5th Floor CME/MOC: 1.0; CE: 1.0 Moderator: Sarah Cuddy, MB ChB 3:30 PM How Has #SoMe Impacted My Knowledge in the Field of Cardiac Imaging? A Fellow In Training Perspective Ahmad Masri, MD How Does #SoMe Impact Career Development? M. Chadi Alraies, MD How Has #SoMe Impacted the Field of Cardiac Imaging and Nuclear Cardiology? Renee Bullock–Palmer, MD, FASNC Impact of #SoMe on Mentoring and Education: A Perspective from an Established Cardiologist Jennifer H. Mieres, MD, MASNC 4:15 PM Questions and Answers

Technology & Techniques TT–04. Stress Testing for Technologists: The Cardiology of Nuclear Location: Belmont, 4th Floor CME/MOC: 1; CE: 1 Moderators: Mark C. Hyun, CNMT, NCT, RT(N)(R), FASNC and Maria L. Mackin, CNMT, RT, RT(N) 3:30 PM Pharmacologic Stress Testing: Who and How? R. Parker Ward, MD, FASNC 3:50 PM Exercise Testing: Who and How? Gregory S. Thomas, MD, MPH, MASNC 4:10 PM Stress Testing Urgencies and Emergencies Thomas A. Holly, MD, FASNC

47 www.asnc.org/ASNC2019 SATURDAY, SEPTEMBER 14

321. ePoster Session V: SPECT Diagnosis and Prognosis Location: North Alcove, 7th Floor Poster Discussant: Raymond R. Russell, III, MD, PhD, MASNC CME/MOC: 1.0; CE: 0

321–01 3:35 PM Global And Regional Coronary Flow Reserve L. Philippe*, C. Prunier–Aesch, Y. El Yaagoubi; Medecine Assessed By Routine 99mTc–tetrofosmin SPECT Nucleaire Tourangelle, Chambray–les–Tours, France 321–02 3:45 PM Correlations Between Left Bundle Branch Block A. Rizkallah*,1 S. L. Liao,2 K. A. Demers,3 J. Gerlach,4 K. Related Perfusion Defects and Left Ventricular Lara,5 P. J. Slomka,4 W. Duvall6; 1University Dyssynchrony of Connecticut – Hartford Hospital, Hartford, CT, 2Cardiology, The Mount Sinai Medical Center, New York, NY, 3Nuclear Cardiology, The Mount Sinai Medical Center, New York, NY, 4Cedars–Sinai Medical Center, Los Angeles, CA, 5Cardiology, Mayo Clinic, Rochester, MN, 6Nuclear Cardiology, University of Connecticut – Hartford Hospital, Hartford, CT 321–03 3:55 PM Effect Of Radiotracer Infiltration On Automated A. Sharma*,1 G. Pershwitz,1 T. M. Morneau,2 G. Heald,1 G. Quantification of SPECT Myocardial Perfusion Tadeo,1 D. Pelletier,1 F. Quevedo,1 S. R. McMahon,3 W. Duvall4; 1Hartford Hospital, Hartford, CT, 2Non–Invasive Cardiology, Hartford Hospital, Hartford, CT, 3Cardiology, Hartford hospital, Hartford, CT, 4Nuclear Cardiology, Hartford Hospital, Hartford, CT 321–04 4:05 PM Percentage Of Normal Patients From A Nuclear C. D. Cooke*,1 R. Eppes,1 K. F. Van Train,1 E. V. Cardiology Database of 120,000 Studies Garcia2; 1Syntermed, Inc., Atlanta, GA, 2Radiology, Emory University Hospital, Atlanta, GA 321–05 4:15 PM SPECT Myocardial Blood Flow Quantification Is L. Wang*,1 J. Li,2 Y. Zheng,3 B. Hsu,4 W. Fang1; 1Chinese Superior To Myocardial Perfusion Imaging For Academy of Medical Sciences Fuwai Hospital, Beijing, Detection Of Coronary Artery Disease: A Multi– China, 2Teda International Cardiovascular Hospital, center Trial Tianjin, China, 3China–Japan Friendship Hospital, Beijing, China, 4Nuclear Science and Engineering Institute, University of Missouri–Columbia, Columbia, MO

*Denotes presenting author.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 48 ASNC EDUCATION

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322. Poster Session V: New Developments in Cardiac PET Location: 7th Floor Foyer Poster Discussant: Venkatesh L. Murthy, MD, PhD, FASNC CME/MOC: 1.0; CE: 0

322–01 Count Rate Performance Evaluation Of 3d PET R. Prasad*,1 M. Malecki,1 A. Rybczynski,1 S. Virmani,2 J. 82 1 1 1 System For Rbcl2 Myocardial Dynamic Imaging Singh, R. Sanghani ; Rush University Medical Center, Chicago, IL, 2Radiology, RUSH University Medical Center, Chicago, IL 322–02 Blood Glucose Status Mediates Microvascular A. Aljizeeri*,1 M. Alali Alfaris,1 D. Ahmed,1 J. Farea,1 A. Dysfunction In Patients Referred For Positron Elneama,1 I. Alharbi,1 I. Suliman,1 A. Ahmed,1 M. Emission Tomography Alharthi,1 A. Alsaileek,1 M. H. Al–Mallah2; 1King Abdulaziz Cardiac Center, Riyadh, Saudi Arabia, 2Houston Methodist DeBakey, Houston, TX 322–03 Normal Values For Myocardial Blood Flow And D. Harland*, D. Mahlum, J. Falk, P. Galazka, S. Port; Myocardial Flow Reserve Using82Rubidium Advocate Aurora Health Care, Milwaukee, WI And A Dedicated Cardiac Positron Emission Tomography (PET) Scanner With A Hybrid 2D/3D Acquisition Protocol 322–04 Does Cardiac PET Myocardial Perfusion Imaging J. Fisher*,1 S. Selvin,2 G. V. Heller,2 S. Curran,1 T. In A Clinical Practice Change Referral For And Mathur,1 L. Immordino,1 S. Chandhok,1 F. Day,1 J. Outcomes At Cardiac Catheterization? Hazel–Dabagian,1 J. Steers,1 G. Harper,1 L. Mendelson,1H. Kramer,1 S. Mangalmurti1; 1Bryn Mawr Hospital, Lankenau Heart Institute, Bryn Mawr, PA, 2Molecular Imaging Services, Newark, DE 322–05 Role Of NaF PET/CT In Assessing Aortic Valve C. Rojulpote*,1 W. Y. Raynor,1 S. Seraj,1 T. J. Calcification And Its Correlation With Age Werner,1 P. Hoilund–Carlsen,2 A. Alavi3; 1University of Pennsylvania, Philadelphia, PA, 2Odense University Hospital, Odense, Denmark, 3Radiology, University of Pennsylvania, Philadelphia, PA

*Denotes presenting author.

4:00 PM – 7:00 PM Off–site Education WL–02. Sail and Learn: Architectural Boat Tour Location: Chicago Ballroom H, 5th Floor CME/MOC: 1; CE: 0 4:00 PM Appropriate Use Criteria: Incorporating the AUC into Your Practice Robert C. Hendel, MD, MASNC and Jeffrey A. Leppo, MD, MASNC 4:45 PM Depart for Boat Tour 5:30 PM Boat Tour begins 7:00 PM Boat Tour ends

49 www.asnc.org/ASNC2019 SATURDAY, SEPTEMBER 14

4:30 PM – 6:00 PM PET PET–02. Debates in Cardiac PET: Clash of the Photons Location: Chicago Ballroom E, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Donna M. Polk, MD, MPH, FASNC and Raymond R. Russell III, MD, PhD, MASNC 4:30 PM Introduction: Cardiac PET Should Replace SPECT Ronald G. Schwartz, MD MS, MASNC Cardiac PET Should Replace SPECT: Pro Venkatesh L. Murthy, MD, PhD, FASNC Cardiac PET Should Replace SPECT: Con Terrence D. Ruddy, MD, FASNC Questions and Answers: Cardiac PET Should Replace SPECT Ronald G. Schwartz, MD MS, MASNC Introduction: PET MFR Should Be Reported Manuel D. Cerqueira, MD, MASNC PET MFR Should Be Reported: Pro K. Lance Gould, MD PET MFR Should Be Reported: Con Todd D. Miller, MD, MASNC Questions and Answers: PET MFR Should Be Reported Manuel D. Cerqueira, MD, MASNC Introduction: Image Cardiac Sarcoidosis: The First Test Should Be ⋯ Mouaz H. Al–Mallah, MD, MSc, FASNC Image Cardiac Sarcoidosis: The First Test Should Be ⋯ MRI Amit R. Patel, MD Image Cardiac Sarcoidosis: The First Test Should Be ⋯ PET Edward J. Miller, MD, PhD, FASNC 5:45 PM Questions and Answers: Image Cardiac Sarcoidosis: The First Test Should Be ⋯ Mouaz H. Al–Mallah, MD, MSc, FASNC

Cases with the Aces CA–06. Focus on Myocardial Blood Flow: Cases from Mid America Heart Location: Armitage, 4th Floor CME/MOC: 1.5; CE: 1.5 Case Presenters: Timothy M. Bateman, MD, MASNC and A. Iain McGhie, MD

Ticketed session.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 50 ASNC EDUCATION

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Advanced A–03. Predicting the Future: Machine Learning and Big Data in Cardiac Imaging Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Myron C. Gerson, MD, MASNC and Ernest V. Garcia, PhD, MASNC 4:30 PM Outcome Prediction Khurram Nasir, MD, MPH 4:50 PM Image Analysis in Nuclear and CT James A. Case, PhD, FASNC 5:10 PM Practice Analytics to Improve Quality Raymond J. Gibbons, MD, MASNC 5:30 PM Imaging Phenotypes Albert J. Sinusas, MD, FASNC 5:50 PM Panel Discussion

Image–based Case Management CM–05. The “I’s” Have It: Advanced PET Imaging for Inflammation, Infection, and Infiltration Location: Chicago Ballroom G, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Ron Blankstein, MD, FASNC and Richard Weinberg, MD, PhD, FASNC 4:30 PM Inflammation: Sarcoid Evaluation with PET and MR – Case Presenter Balaji K. Tamarappoo, MD, PhD 4:35 PM Inflammation: Sarcoid Evaluation with PET and MR – Discussant John Bois, MD 4:50 PM Infection: Device or Valve – Case Presenter Richard Weinberg, MD, PhD, FASNC 4:55 PM Infection: Device or Valve – Discussant Maryam Mahmood, MD 5:10 PM Inflammation: Vasculitis – Case Presenter Fernando Mut, MD 5:15 PM Inflammation: Vasculitis – Discussant Firas Al Badarin, MD, FASNC 5:30 PM Panel Discussion

6:15 PM – 7:30 PM Evening Workshop (non-CME) SAT–08. Coronary Physiology to Guide CAD Management: Measurements, Meaning and Mortality (non–CME) K. Lance Gould, MD Martin Bucksbaum Distinguished University Chair, Professor of Cardiovascular Medicine, and Executive Director, Weatherhead P.E.T. Center for Preventing and Reversing Atherosclerosis, University of Texas Medical School Sponsored by Bracco Diagnostics Inc. Location: Marriott Ballroom, 4th Floor

51 www.asnc.org/ASNC2019 SUNDAY, SEPTEMBER 15

7:00 AM – 12:00 PM Speaker Ready Room Location: Denver, 5th Floor

8:00 AM – 9:30 AM Plenary PL–05. Mindful Myocardium: Imaging to Delineate the Brain–Heart Continuum Location: Chicago Ballroom D, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Robert J. Gropler, MD, MASNC and Jeroen J. Bax, MD, PhD, FASNC 8:00 AM White Matter Hyperintensities in CV Disease Chiara Bucciarelli–Ducci, MD, PhD, FESC, FRCP 8:25 AM Cross Talk Between Emotional Stress and CVD Ahmed Tawakol, MD 8:50 AM Inflammatory Links between ACS and Stroke Robert J. Gropler, MD, MASNC 9:15 AM Panel Discussion

9:45 AM – 11:15 AM Intersocietal Multimodality Imaging IM–05. Heart Failure of Unknown Etiology: What to Know After the ECHO? Location: Chicago Ballroom E, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Gregory S. Thomas, MD, MPH, MASNC and Brian G. Abbott, MD, MASNC 9:45 AM Etiologies and Treatment: What Can Imaging Provide Heart Failure Specialist? Gary R. Small, MD 10:00 AM Evaluation of Possible CAD: Ischemia and Viability Testing Rami Doukky, MD, FASNC 10:15 AM Anatomical Testing (ICA or CTA) Benjamin Chow, MD, FASNC 10:30 AM MRI: Infiltrative Properties Chiara Bucciarelli–Ducci, MD, PhD 10:45 AM Panel Discussion with Case and Follow–up Image Interpretation Gary R. Small, MD

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 52 ASNC EDUCATION

SUNDAY, SEPTEMBER 15

PET–03. Myocardial Perfusion by PET Location: Chicago Ballroom F, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Erick Alexanderson, MD and Raymond R. Russell III, MD, PhD, MASNC 9:45 AM PET vs. CT–FFR and MRI Philipp A. Kaufmann, MD 10:05 AM Prognostic Value of Absolute Blood Flow K. Lance Gould, MD 10:25 AM Microvascular Angina Diagnosed by Flow Quantification Thomas H. Schindler, MD 10:45 AM Selection for Invasive Angiography/Hemodynamics after Cardiac PET Randall C. Thompson, MD, FASNC 11:05 AM Panel Discussion

Team–based Learning TB–03. Optimize Your Nuclear Lab to Exceed Your Ex–SPECT–ations! Location: Chicago Ballroom G, 5th Floor CME/MOC: 1.5; CE: 1.5 Moderators: Ami E. Iskandrian, MD, PhD, MASNC and Saurabh Malhotra, MD, MPH, FASNC 9:45 AM SPECT Imaging Protocols to Improve Laboratory Throughput Vikas Veeranna, MD 10:00 AM Imaging Protocols for Radiation Reduction Saurabh Malhotra, MD, MPH, FASNC 10:15 AM Imaging a Difficult Patient: Obese, Unable to Lie Supine and Motion Maria L. Mackin, CNMT, RT, RT(N) 10:30 AM Choice of SPECT Camera: CZT or Conventional Joseph Dietz, CNMT 10:45 AM Planar and SPECT PYP – Putting it all Together Javier A. Gomez Valencia, MD 11:00 AM Panel Discussion

53 www.asnc.org/ASNC2019 SUNDAY, SEPTEMBER 15

11:30 AM – 12:45 PM

Team–based Learning TB–04. A Day in the Life of a Nuclear Cardiology Laboratory Location: Chicago Ballroom F, 5th Floor CME/MOC: 1.25; CE: 1.25 Moderators: Karthikeyan Ananthasubramaniam, MD, FASNC and Keiichiro Yoshinaga, MD, PhD, FASNC 11:30 AM Stress MPI in a Patient Who is Unable to Achieve Desired Functional Capacity Sarah Voll, ACNP–BC 11:45 AM Vasodilator Reversal in the Era of Aminophylline Shortage Brian G. Abbott, MD, MASNC 12:00 PM Dietary Preparation for Sarcoid PET: Ensuring Adherence and Diagnostic Quality Kori T. Wilcox, RN 12:15 PM Avoiding Artifacts with Cardiac PET Firas Al Badarin, MD, FASNC 12:15 PM Panel Discussion

PET–04. Perfecting the Performance of PET in Your Practice Location: Chicago Ballroom E, 5th Floor CME/MOC: 1.25; CE: 1.25 Moderators: Robert Bober, MD and Manuel D. Cerqueira, MD, MASNC 11:30 AM How to Choose a PET Camera Robert A. deKemp, PhD 11:45 AM Current and Upcoming Radiotracers Jamshid Maddahi, MD, FASNC 12:00 PM Tips and Tricks for PET/CT Acquisition and Processing Mouaz H. Al–Mallah, MD, MSc, FASNC 12:15 PM PET Reporting: Unique Aspects and Challenges Gary V. Heller, MD, PhD, MASNC 12:30 PM Panel Discussion

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 54 SOCIAL MEDIA AMBASSADORS

We encourage you to use the official meeting hashtag #ASNC2019 to:

ASNC • View latest updates SOCIAL MEDIA • Engage with colleagues and ASNC @MyASNC #ASNC2019 • Post and share live from the meeting • For tips and ideas visit asnc.org/socialmediakit

Image Guided Multimodality Plenary Royals Care Angels Mavericks Kim A. Williams, Niti R. Aggarwal, Ron Blankstein, Sr., MD, MASNC MD, FASNC MD, FASNC @cardio10s @NitiCardio @RonBlankstein

Sharmila Dorbala, Suman Tandon, Sarah Cuddy, MB MD, MPH, FASNC MD, FASNC ChB @DorbalaSharmila @heartsmartpro @sarahcud

Renee Bullock- Brett W. Sperry, MD Edward J. Miller, Palmer, MD, FASNC @BrettSperryMD MD, PhD, FASNC @RBP0612 @edwardmillermd RBP0612 \\ Niti R. Aggarwal, MD, FASNC Ahmad Masri, MD @NitiCardio @MasriAhmadMD \\

Team-Based Spirit Parham Eshtehardi, MD @CoronaryDoc

Lawrence M. Phillips, MD, FASNC @LPhillipsMD

55 www.asnc.org/ASNC2019 Policy Patrol Social Media PET Annihilators Heavyweights Krishna K. Patel, Nishant Shah, MD MD, MPH, FASNC Parham Eshtehardi, MD @krishnapatel888 @nishantshahmd @CoronaryDoc

Kim A. Williams, Sr., Abbas Emaminia, MD, MASNC MD Purvi Parwani, MD @cardio10s @RezaEmaminia @purviparwani

Specialty Stars Viet Le, PA-C Advanced Avengers @VietHeartPA Rami Doukky, MD, FASNC @RamiDoukky Mouaz H. Al-Mallah, MD, MSc, FASNC @almallahmo Suman Tandon, MD, FASNC @heartsmartpro M. Chadi Alraies, MD @chadialraies

Tweet Up Social: Come Tweet with Us! Want to join other Tweeters and join in a fun and productive conversation about #ASNC2019? 1. Log into Twitter or open an account at Twitter.com 2. Turn on the Twitter notifications setting. 3. Follow any of the Social Media Ambassadors and watch for them to announce the secret hash tag code. 4. Tweet the secret hash tag code in a Tweet, such as: I am ready for the #ASNC20 #TweetUpSocial! See you there! @MyASNC [Insert secret hash tag code here.] 5. Bring your phone to the event showing your Tweet, so you can receive one free drink ticket.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 56 ASNC2019 Attendees Get your FREE PROFESSIONAL HEADSHOT Update your professional photo at BOOTH 702 during dedicated Expo Hall hours:

September 13, 2019 8:30 AM – 12:15 PM 1:30 PM – 4:30 PM Brought to you by September 14, 2019 8:30 AM – 12:15 PM 1:30 PM – 4:30 PM Visit us at Booth #200

Connect & Network: THE CHOOSING WISELY® CHALLENGE Welcome to Saturday, September 14, 2019 | 2:00 pm - 3:30 pm | Chicago Ballroom F the ASNC2019 Vote for the Winner of the Nuclear Cardiology Choosing Wisely® Challenge See the three finalists present practice innovations that support appropriate use, Networking Lounge optimizing radiation dose, and enhanced communications with referring clinicians Audience voting will combine with a judging panel to select the top prize winner! Take a break, check your (Passport Loop Card Session) email, post a few #ASNC2019 tweets, connect with faculty Multi-pronged approach to optimize nuclear cardiology testing and improve safety at Kaiser Permanente, Mid-Atlantic states (Virginia, Maryland, Washington DC) and attendees. The lounge Sudip Saha, MD; Joseph Lodato, MD; Nancy Ortiz, MPH, CPHQ, PMP is the ASNC2019 hot spot for Mid Atlantic Permanente Medical Group communication, connection, Development of a patient centered, cost effective algorithm utilizing and collaboration! 99mTechnetium-Pyrophosphate imaging to diagnose ATTR cardiac amyloidosis Benita Philip, DO; Barbara Schechter, DO; Denise Kale, CNMT; Renee P. Bullock-Palmer, MD, FASNC Sponsored by Department of Cardiology, Deborah Heart and Lung Center

Impact of a novel myocardial perfusion imaging risk classification scheme on referral for coronary angiography, revascularization, and mortality Anirudh Kumar, MD; Paul Cremer, MD; Rory Hachamovitch, MD, FASNC; Wael Jaber, MD Cleveland Clinic Foundation

Moderator: David G. Wolinsky, MD, MASNC ASNC thanks Bracco Diagnostics Committee: Renee Bullock-Palmer, MD, FASNC; Inc. for support of Maria G. Sciammarella, MD; Wael Jaber, MD; this program. Todd D. Miller, MD, MASNC; Chairperson: Paul Cremer, MD

30mm 57 www.asnc.org/ASNC2019 60mm ASNC’S INTERNATIONAL PARTNERS

Argentine Federation of Cardiology International Atomic Energy Agency (IAEA) Argentine Society of Cardiology Japanese Society of Nuclear Cardiology Asia Oceania Federation of Japanese Society of Nuclear Medicine Nuclear Medicine and Biology Kuwait Society of Nuclear Medicine Brazilian Society of Cardiology Latin American Association of British Nuclear Cardology Society Biology and Nuclear Medicine Canadian Association of Nuclear Medicine Mexican Society of Cardiology Chinese Society of Nuclear Medicine Saudi Heart Association Egyptian Society of Cardiology Spanish Society of Nuclear Medicine and Molecular Imaging European Association of Cardiovascular Imaging Turkish Society of Nuclear Medicine European Association of Nuclear Medicine World Federation of Nuclear European Society of Cardiology Medicine and Biology Inter-American Society of Cardiology

Download the #ASNC2019 Mobile App Get session information, create a personalized agenda, and search exhibitors

Download the ASNC2019 mobile app for FREE on your iPhone, iPad, or Android device and get access to ASNC2019 sessions and events, networking resources, social media updates, and exhibitor information. The app includes these features: • Event Agenda DIRECTIONS: • Speaker and Participant Information 1. Visit your device’s app store 2. Search for ASNC2019 • Interactive Personalized Agenda 3. Click the available link 4. Click Install and accept the • Exhibitor Listings and Floorplan app’s terms of usage • Real-time Polls and Surveys 5. Allow app notifications 6. Click Open to access the • Venue and Area Maps app or visit the device’s home screen and click the • Meeting Information corresponding icon 7. Type in your preferred email • Alerts and Updates address, create your profile and enjoy!

Corporate support provided by

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 58 GENERAL INFORMATION

AMERICANS WITH DISABILITIES ACT COAT AND BAGGAGE CHECK

ASNC supports the Americans with Disabilities Act and we ASNC does not provide coat or baggage check. Bags may be will be glad to assist you with any special needs to make this checked at the bell stand in the hotel lobby. program accessible to you. MOBILE APP ADMISSION REQUIREMENTS Please go to page 57 in this program to view download Admission to all sessions and the exhibit hall is by badge only. instructions for the ASNC2019 mobile app. Entry to the Expo Hall is restricted to individuals over 18 years Corporate support provided by of age.

ASNC BOOTH MOBILE PHONES, PAGERS, OTHER ELECTRONIC DEVICES Located outside the Expo Hall. For consideration of others, please remember to silence all Thursday, September 12, 11:00 am – 8:00 pm – 7th Floor electronic devices while in educational sessions. Grand Ballroom – Opening Reception Friday, September 13, 8:30 am – 4:30 pm – 7th Floor NO SMOKING POLICY Grand Ballroom (Closed 12:15-1:15 pm) Smoking is prohibited in the Marriott Chicago Downtown Saturday, September 14, 8:30 am – 4:30 pm – 7th Floor Magnificent Mile. This includes meeting space, restaurants and Grand Ballroom (Closed 12:15-1:15 pm) sleeping rooms. Your compliance is appreciated.

SPEAKER READY ROOM BEACONS AT ASNC2019 ASNC requests that faculty use the audio-visual equipment in If you are attending ASNC2019 in Chicago, you may notice a the speaker ready room to prepare presentations. The Speaker small rectangular object on the back of your badge. The object Ready room is located in the Denver room located on the 5th is a beacon, a small wireless device that broadcasts a unique Level of the Marriott Chicago Downtown Magnificent Mile. The signal using Bluetooth Smart technology, which can be read room will be staffed with technicians to assist faculty: by receivers located in the session rooms, networking areas, Thursday, September 12, 10:00 a.m. – 6:00 p.m. and Expo Hall. Every session room within the Chicago Marriott Friday, September 13, 7:00 a.m. – 5:00 p.m. Downtown will be set up with receivers to track attendee Saturday, September 14, 7:00 a.m. – 5:00 p.m. movements in and out of sessions. The beacons will also allow us Sunday, September 15, 7:00 a.m. – 12:00 p.m. to facilitate the credit claiming process. The wearable beacon technology will help us make our Annual Scientific Session better, WI-FI AVAILABLE and understand what works and what does not. From recent surveys, we learned that attendees want a more personalized Wi-Fi is available in the Education rooms and public areas of experience. Using beacon technology is a sophisticated way to the Marriott Chicago Downtown Magnificent Mile. enhance our attendees’ experience. We have partnered with Corporate support provided by TurnoutNow to employ their wearable beacon technology and data analytics to provide us with this level of detail. TurnoutNow Access Wi-Fi by entering: does not copy, store, or release any of our data, so it’s the most Username: ASNC2019 secure solution. Review our Privacy Policy on our website, which Password: astellas outlines how and when your data is shared.

ASNC2019 MEETING ON DEMAND

All attendees can obtain an access code to the ASNC2019 The non-CME ASNC2019 Meeting On Demand by visiting Bracco Diagnostics Inc. at Meeting On Demand is MOD sponsored by booth #409 in the Expo Hall. This is a non-CME product. Visit the registration desk to purchase the ASNC2019 CME Meeting On Demand.

30mm 60mm

59 www.asnc.org/ASNC2019 VENUE MAPS

4TH FLOOR EXPO HALL Registration

Satellite Symposia (Marriott Ballroom) Cases With the Aces (Armitage) Ticketed session Technology and Techniques (Belmont)

5TH FLOOR

Registration* Posters ePosters ASNC Booth Expo Hall ImageGuide Booth Rapid Fire ePosters

* Registration is on the 5th floor on Tuesday and Wednesday.

Board Prep and Plenary (Chicago Ballroom D) Breakout (Chicago Ballroom E) Breakout (Chicago Ballroom F) Breakout (Chicago Ballroom G) Breakout (Chicago Ballroom H)

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 60 ASNC2019 EXPO HALL FLOOR

7TH FLOOR

F005

61 www.asnc.org/ASNC2019 EXPO HALL EVENTS

EXPO HALL HOURS SEPTEMBER 13, 2019 Saturday, Sept. 14 Friday, September 13 3:30 PM – 4:30 PM 9:30 AM – 10:30 PM PET Flow 8:30 AM – 12:30 PM CASES OVER COCKTAILS 1: 10:30 AM – 11:30 AM PET Viability 11:30 AM – 12:30 PM SPECT MPI 1:15 PM – 4:30 PM 3:30 PM – 4:00 PM 1:30 PM – 2:30 PM PYP Saturday, September 14 CASES OVER COCKTAILS 2: 2:30 PM – 3:30 PM SPECT MUGA 8:30 AM – 12:30 PM 4:00 PM – 4:30 PM 3:30 PM – 4:30 PM Sarcoid 1:15 PM – 4:30 PM

FRIDAY CASES OVER COCKTAILS Software demos available: FRIDAY, SEPTEMBER 13, 2019 Join Alnylam Pharmaceuticals for aQuant – MedTrace Cocktails and Case Review in the Expo FRIDAY COFFEE BREAK ImagenPRO, ImagenQ, ImagenSPECT Hall during the Friday afternoon break! 9:45 AM – 10:30 AM - Cardiovascular Imaging Technologies There will be two identical presentations (CVIT) FRIDAY DESSERT RECEPTION & PRIZE 3:00 PM – 3:30 PM and DRAWING 3:30 PM – 4:00 PM. Cedars-Sinai Medical Center Cardiac Suite 1:30 PM – 2:00 PM Corridor4DM – INVIA Satellite Session Emory Toolbox – Syntermed FRIDAY CASES OVER COCKTAILS SAT–04. Cases Over Cocktails 3:30 PM – 4:30 PM hATTR Amyloidosis: The Mixed FlowQuant – University of Ottawa Heart Phenotype Patient Institute Nithasha Sarswat, MD HeartSee – Bracco Diagnostics Inc. SATURDAY, SEPTEMBER 14, 2019 Director, Cardiac Amyloid Program SATURDAY COFFEE BREAK Advanced Heart Failure, Mechanical Cir- 9:30 AM – 10:30 AM culatory Support and Transplantation Learn with Leaders! The following University of Chicago leaders (and more!) in the field of nuclear SATURDAY DESSERT Location: Expo Hall, 7th Floor cardiology are scheduled to be in the RECEPTION & PRIZE DRAWING Learning Lab Friday and Saturday. Check 1:30 PM – 2:00 PM Sponsored by the onsite schedule to find out when! SATURDAY EXPO HALL BREAK Timothy M. Bateman, MD, MASNC & PRIZE DRAWING HANDS-ON SIMULATION LAB: Robert Bober, MD, FRCPC 3:30 PM – 4:30 PM LEARN WITH LEADERS James A. Case, PhD, FASNC Shaping September 13 9:30 AM – 3:30 PM Panithaya Chareonthaitawee, MD

THE LOOP CARD A91CC-9639-A1 the future of September 14 9:30 AM – 4:30 PM Robert deKemp, BASc, MSc, PhD, PEng, Bring the ASNC2019 Loop Card with you PPhys healthcareto the Expo Hall and Satellite Sessions to Location: Expo Hall, 7th Floor Sharmila Dorbala, MD, MPH, FASNC At Siemens Healthineers,receive stamps. Give your completed Loop Join leaders in the field of nuclear our purpose is to enable Gary V. Heller, MD, PhD, MASNC healthcare providers to Card to ASNC staff at the conclusion of cardiology to review and discuss cases increase value by empowering Nils P. Johnson, MD, MS them on their journey towardsthe Saturday evening Bracco Diagnostics while testing out various imaging software. expanding precision medicine,Dinner Workshop to be entered into the transforming care delivery, A sign-up sheet will be posted at the Prem Soman, MD, PhD, MASNC and improving patient drawing for one of four Apple gift cards. experience, all enabled by Learning Lab in the Expo Hall. Reserve Randall C. Thompson, MD, MASNC digitalizing healthcare. GOOD LUCK AND HAVE FUN! your one-hour time slot early for this rare R. Glenn Wells, BSc, MSc, PhD, FCCPM siemens-healthineers.us opportunity! The preliminary schedule for case review is below.

30mm 60mm Friday, Sept. 13 9:30 AM – 10:30 AM PET Flow 10:30 AM – 11:30 AM PET Viability 11:30 AM – 12:30 PM SPECT MPI 1:30 PM – 2:30 PM PYP PROOF2:30 PM – 3:30 PM PET MPI *4th Apple Gift Card drawing at Bracco Diagnostics Inc. Evening Workshop. Winner must be present.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 62 Shaping the future of A91CC-9639-A1 healthcare At Siemens Healthineers, our purpose is to enable healthcare providers to increase value by empowering them on their journey towards expanding precision medicine, transforming care delivery, and improving patient experience, all enabled by digitalizing healthcare.

siemens-healthineers.us

63 www.asnc.org/ASNC2019 PROOF EXHIBITOR LISTING

Absolute Imaging Solutions 210 American Society of Nuclear Cardiology Expo Hall Foyer Absolute Imaging Solutions (AIS) is the Molecular Imaging ASNC is the recognized leader in quality, education, advocacy experts in New/Reconditioned SPECT Cameras- Service- and standards in cardiovascular imaging, with more than Processing Workstations and Parts. AIS is the exclusive source 4,500 members worldwide. ASNC establishes standards for the Mediso AnyScan® S, enabling healthcare providers for excellence in cardiovascular imaging through the a cost-effective NEW SPECT alternative with integration into development of clinical guidelines, professional education, various clinical settings. advocacy and research development to improve patient outcomes. www.asnc.org

Akcea Therapeutics, Inc. 604 Akcea Therapeutics, Inc., an affiliate of Ionis Pharmaceuticals, Astellas Pharma US, Inc. 401 Inc. is a biopharmaceutical company focused on developing Astellas Pharma US, Inc., is a U.S. affiliate of Tokyo-based and commercializing drugs to treat patients with serious and Astellas Pharma Inc. Located in Northbrook, Illinois, the rare diseases. Akcea is advancing a mature pipeline of six company serves as the headquarters for the Americas and novel drugs, including TEGSEDI™ (inotersen), WAYLIVRA™ employs nearly 3,000 people. Astellas is a pharmaceutical (volanesorsen), AKCEA-APO(a)-LRx, AKCEA-ANGPTL3-LRx, company dedicated to improving the health of people around AKCEA-APOCIII-LRx, and AKCEA-TTR-LRx, with the potential the world through the provision of innovative and reliable to treat multiple diseases. All six drugs were discovered by pharmaceutical products. and are being co-developed with Ionis, a leader in antisense therapeutics, and are based on Ionis’ proprietary antisense technology. TEGSEDI is approved in the U.S., E.U. and Canada. Bracco Diagnostics Inc. 409 WAYLIVRA is under regulatory review for the treatment of Bracco Diagnostics Inc. (BDI), the U.S.-based subsidiary familial chylomicronemia syndrome, or FCS, and is currently of Bracco Imaging SpA, and part of the Bracco Group, is in Phase 3 clinical development for the treatment of people a leader in innovative contrast imaging agents, specialty with familial partial lipodystrophy, or FPL. Akcea is building the radiopharmaceuticals and medical devices in the U.S. infrastructure to commercialize its drugs globally. Established in 1994, with headquarters and research offices in Monroe Township, NJ, Bracco Diagnostics offers solutions for all key diagnostic imaging modalities: X-Ray Imaging, Magnetic Alnylam Pharmaceuticals 101 Resonance Imaging (MRI), Contrast Enhanced Ultrasound Headquartered in Cambridge, MA, Alnylam is leading the (CEUS), and Nuclear Medicine. translation of RNA interference (RNAi) into a new class of innovative medicines with the potential to transform the lives of people with rare genetic, cardio-metabolic, hepatic CDL Nuclear Technologies 602 infectious, and central nervous system/ocular diseases. Based Cardiac PET Starts Here. CDL Nuclear Technologies is a on Nobel Prize-winning science, RNAi therapeutics represent nationwide nuclear cardiac imaging company that has delivered a clinically validated approach for the treatment of diseases solutions to healthcare providers since 1992. As the nation’s with high unmet need. Alnylam’s first U.S. FDA-approved RNAi largest turnkey cardiac PET provider, we are trusted by more therapeutic is ONPATTRO® (patisiran) available in the U.S. for groups to provide a first-class PET program than any other. Our the treatment of the polyneuropathy of hereditary transthyretin- complete project management and low-risk model, with no mediated amyloidosis in adults. Additionally, Alnylam has six upfront cost to you, removes the key barriers preventing you investigational medicines in late-stage development. from expanding your cardiac imaging program. If turnkey isn’t the right fit for you, ask us about CardioNavix, the nation’s only portable Rb-82 program. American College of Radiology 610 The American College of Radiology (ACR®) is a leading professional medical society dedicated to serving patients and society by empowering radiology professionals to advance the practice, science, and professions of radiological care. ACR Accreditation and Appropriateness Criteria are the standards for safe imaging and patient care. The ACR’s 38,000 members include radiologists, radiation oncologists, nuclear medicine physicians and medical physicists.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 64 EXHIBITOR LISTING

Cardiac Imaging, Inc. 605 Certification Board of Nuclear Cardiology (CBNC) / APCA F004 Cardiac Imaging, Inc. has brought together advanced nuclear medicine technology with convenient care through our turnkey The Certification Board of Nuclear Cardiology (CBNC), the mobile medical clinics and mobile cardiac PET scanning Certification Board of Cardiovascular Computed Tomography exams. Learn more about our medical PET scans and exams. (CBCCT), and the Certification Board of Cardiovascular Our mobile cardiac PET scanning and imaging services allow Magnetic Resonance (CBCMR) certification programs were physicians to treat their patients for cardiac disease with the established to develop and administer practice-related most cutting-edge tools in nuclear medicine, without leaving examinations in the field of Nuclear Cardiology, Cardiovascular the comfort of their practice. We exclusively perform mobile Computed Tomography, and Cardiovascular Magnetic cardiac positron emission tomography (PET) imaging exams, Resonance. In addition, the CBNC, CBCCT and CBCMR were the recognized gold standard across the United States in established to award certification to those physicians who detecting early coronary artery disease before it is evident on successfully complete the examination process. APCA has other imaging tests. By partnering with us, we perform every over 21,000 certified physicians throughout the world and is aspect of the cardiac PET scan and exam so that your main part of the non-profit Inteleos™ family of certification alliances. focus is treating your patient.

Dejavi Innovations, Inc. 612 Cardiovascular Imaging Technologies 513 Dejavi Innovations, Inc. uses a non-surgical sonic device that CVIT is a research and development company focusing on employs light-emitting diodes (LEDs) -- a special type of light practical solutions for achieving high-quality, maximally- source that releases energy in the form of photons – for skin efficient cardiac SPECT, PET, and CT imaging. CVIT offers treatments. Dejavi Innovations, Inc. also offers non-surgical eye training, preceptorships, processing software, and quality treatments. control software designed to improve quality and workflows in cardiac imaging. CVIT organizes, participates in, and Digirad 200 functions as a core imaging lab for research studies leading to advances in the prevention, diagnosis, and treatment of Digirad sets the gold standard in customer service and patient cardiovascular diseases. We have developed, 510(k) cleared, satisfaction with diagnostic solutions that optimize imaging distribute and service the Imagen family of cardiac imaging at the point of care. For healthcare facilities of all sizes, our products: ImagenPRO, ImagenMD, ImagenQ, Imagen3D, and SPECT and PET MPI services, nuclear products, and support ImagenSPECT. offer outstanding flexibility to improve performance, optimize outcomes, and enhance the patient experience.

Cedars-Sinai 611 eMP10, LLC 608 The Artificial Intelligence in Medicine (AIM) Program at Cedars- Sinai provides state-of-the-art software solutions for cardiac Our product employs the latest in TENS technology. With a SPECT and PET imaging. The quantitative software and fully rechargeable lithium battery, our devices are portable and algorithms developed by Cedars-Sinai, including QGSTM and easy to use. QPSTM, are widely considered the gold standard in nuclear cardiology. Visit our booth to learn more about Cedars-Sinai Cardiac Suite and some of its latest features. Empire Tech 609

65 www.asnc.org/ASNC2019 GE Healthcare 307 INVIA Medical Imaging Solutions 503 GE Healthcare provides transformational medical technologies INVIA is dedicated to developing advanced non-invasive and services to meet the demand for increased access, cardiac imaging software for medical professionals to optimize enhanced quality and more affordable healthcare around patient care. Physicians use our software, 4DM, to accurately the world. GE (NYSE: GE) works on things that matter - great quantify, review, and report cardiac perfusion, function, and people and technologies taking on tough challenges. anatomy. 4DM is available integrated with more than 25 From medical imaging, software & IT, patient monitoring camera, workstation, EMR and PACS manufacturers, or as a and diagnostics to drug discovery, biopharmaceutical software-only solution for Windows laptops and workstations. manufacturing technologies and performance improvement Originating at the University of Michigan twenty years ago, we solutions, GE Healthcare helps medical professionals deliver developed 4DM with the patient in mind – enabling physicians great healthcare to their patients. around the world to make accurate interpretations.

Hitachi Healthcare 113 Ionetix 207 Hitachi Healthcare Americas delivers best in class medical Ionetix Corporation is the first national supplier of N-13 ammonia imaging technologies for healthcare providers. Hitachi’s MRI, for use with cardiac Positron Emission Tomography (PET) CT, US and X-Ray and VidiStar’s technologies provide speed, imaging. N-13 Ammonia is a highly accurate myocardial comfort and quality for both radiologists and patients playing perfusion imaging agent used for the detection of coronary an important role in the diagnosis and treatment of disease artery disease (CAD) and is considered a gold standard for while driving social innovation into healthcare. quantification of absolute coronary flow reserve (CFR). Ionetix has developed an ultra-compact, automated, unit dose N-13 ammonia production system. Ionetix will install this system ® ImageGuide Registry F005 directly at the hospital or clinic for on-demand dose availability, The ImageGuide Registry® is the first cardiovascular offering unprecedented access to N-13 Ammonia tracer supply. registry of its kind that provides the framework to support practices committed to continuous patient-centered imaging, practice transformation, and innovation. The ImageGuide Japanese Society of Nuclear Cardiology F001 Registry contains two modules, ImageGuideEcho™ and The Japanese Society of Nuclear Cardiology (JSNC) is the ImageGuideNuclear™, and provides the tools to benchmark leading society for nuclear cardiology in Japan, founded in performance on location, practice, and national levels to achieve October 1998. JSNC includes among its members cardiologists, quality improvement. CMS has recognized the ImageGuide nuclear medicine physicians, radiologists, technologists and Registry as a Qualified Clinical Data Registry (QCDR) since 2015 other professionals dedicated to nuclear cardiology. Every and can be used to meet reporting requirements under the summer we hold annual scientific meeting. Since 2015, we Merit-based Incentive Payment System (MIPS). have published our official English-language journal, Annals of Nuclear Cardiology (http://anc.jsnc.journal.org/), to promote clinical and research work in nuclear cardiology. Intersocietal Accreditation Commission (IAC) F003 For over 25 years IAC has its mission of Improving Health Care Through Accreditation, offering accreditation for vascular Jubilant Radiopharma 201 testing, echocardiography, nuclear/PET, MRI, CT, dental CT, Jubilant DraxImage Inc. develops, manufactures and markets carotid stenting, vein treatment and management, cardiac radiopharmaceuticals and state-of-the-art technologies used for electrophysiology and cardiovascular catheterization. Learn the diagnosis, treatment and/or monitoring of various diseases. about IAC’s tools QI Self-Assessment Tool, QI MOC Activity and They provide high quality and reliable specialty products to QuickFill Reaccreditation at intersocietal.org. hospital-based customers and radiopharmacies worldwide and ultimately through them patients. Their areas of specialization include cardiology, pulmonology, skeletal, and endocrine therapies. They are passionately dedicated to the field and committed to Improving Life through Nuclear Medicine.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 66 EXHIBITOR LISTING

Lantheus Medical Imaging, Inc. 211 MiE America Inc. 507 Lantheus Medical Imaging, Inc. is a global leader in the MiE America leads the way in the re-manufacturing and development, manufacture and commercialization of manufacturing of nuclear medicine imaging equipment. Our innovative diagnostic imaging agents and products. The SPECT and PET scanners are FDA and CE approved and Company provides a broad portfolio of products serving controlled by SCINTRON. This new computer system provides Echocardiography and Nuclear Medicine specialties. Lantheus’ the most current acquisition and processing protocols not only key products include the echocardiography contrast agent to allow Nuclear Medicine, Cardiology providers or researchers DEFINITY® Vial for (Perflutren Lipid Microsphere) Injectable deliver high quality diagnostic scans to their patients, Suspension and TechneLite® (Technetium Tc99m Generator), but also purchase and/or upgrade to today’s technology a technetium-based generator that provides the essential economically: 3D imaging, dose reduction, faster and state-of- medical isotope used in nuclear medicine procedures. the art processing, longevity, more efficient use of your RB-82 Lantheus is headquartered in North Billerica, Massachusetts generator and cost reduction. with offices in Puerto Rico and Canada.

MIM Software Inc. 509 Marquis Medical 109 MIM Software Inc. provides vendor-neutral solutions for Marquis Medical is the nation’s leading ISO 13485:2016 Certified- multi-modality image fusion, processing, and review for Independent Service Organization specializing in PET, PET/ radiology and nuclear medicine. MIMcardiac® is a vendor- CT & CT expert service, quality reconditioned equipment sales, neutral solution for the quantitative analysis of cardiac PET comprehensive maintenance agreements, mobile imaging and SPECT. LV parameters are generated using a robust and solutions and field service equipment training classes. accurate deformable registration method helping to overcome limitations of traditional threshold methods. Fusion between stress/rest images facilitates comparison of corresponding MedAxiom 108 myocardium and perfusion differences are highlighted in a MedAxiom is a community of health care providers and color-coded display. Multi-modality fusion is also used to innovators dedicated to advancing cardiovascular care. register functional images to CCTA and to correct PET/CT and We offer valuable membership services, expert consulting SPECT/CT misalignment. and industry connections for hundreds of cardiovascular organizations across the country. MedAxiom members benefit from access to exclusive data and analytics, program Modern Nuclear 212 optimization tools, premium educational events, vetted Modern Nuclear Inc. is a Nuclear Medicine Diagnostic industry solutions and peer-to-peer learning. company specializing in Nuclear Cardiology since 1992. We offer mobile Rubidium Cardiac PET and portable Cardiac SPECT MPI as well as consulting or complete set-up of in- house PET and SPECT labs. Our turnkey operation includes MedTrace 706 accreditation, billing, staff, equipment, isotopes, and all MedTrace Pharma is a development-stage company making supplies. Our scanners utilize Cedars-Sinai software and 15O-water practically available. The company has invented a interpretation can be performed by our physicians or your own. point-of-care chemistry lab -MT-100 - that is placed next to All reports and studies are stored on our cloud server, to which the PET scanner which - connected to any kind of cyclotron our clients have 24/7 access. Founded in May 1988 by Patrick - can manufacture and automatically infuse 15O-water into J. Laverty, BS, CNMT, CEO, RSO, Modern Nuclear is accredited the patient. Two working prototypes have been installed in by IAC and has been a certified Medicare provider since 2004. Denmark and the US and the company is preparing for the clinical trial phase III. Besides the hardware, MedTrace has developed an analytical software platform - aQuant - for the interpretation of 15O-water PET images, both absolute flow values as well as clear images.

67 www.asnc.org/ASNC2019 Molecular Imaging Services, Inc. 204 Pfizer 206 Molecular Imaging Services, Inc. provides a comprehensive, At Pfizer, we apply science and our global resources to bring cost effective solution that simplifies adding Cardiac PET to your therapies to people that extend and significantly improve their practice in today’s challenging atmosphere. Our Comprehensive lives. We strive to set the standard for quality, safety and value Support approach has redefined the turnkey model with in the discovery, development and manufacture of health unparalleled Clinical, Operational and Reimbursement resources care products. Our global portfolio includes medicines and and solutions. With the support of our Medical Advisor Gary vaccines as well as many of the world’s best-known consumer Heller, MD, we have solidified the physician education and Quality health care products. Every day, Pfizer colleagues work across Assurance to support your transition to a 1st Class PET Program. developed and emerging markets to advance wellness, Let the MIS Team do the Heavy Lifting! prevention, treatments and cures that challenge the most feared diseases of our time.

NorthStar Medical Radioisotopes, LLC 106 NorthStar Medical Radioisotopes, LLC is a nuclear medicine Prescient Imaging, LLC 607 technology company committed to providing reliable, U.S.- A group of scientist and engineers, with private investment, based and environmentally sustainable radioisotope supply. founded Prescient Imaging, LLC in California with the mission of The FDA-approved and commercially available RadioGenix® developing novel configurations of medical imaging scanners. System (technetium 99m generator), based on non-uranium Our PET scanners are protected by issued and pending molybdenum-99 (Mo-99), enables radiopharmacy production patents. Prescient Imaging is actively soliciting potential clinical of technetium-99m for medically important diagnostic investigators for innovative uses of these devices. Investigators imaging. NorthStar currently provides RadioGenix System are required to a) await institutional review board (IRB) and customers with domestic Mo-99 and continues to expand Food and Drug Administration (FDA) approval before allowing Mo-99 supply and production capacity. The Company is any subject to participate, b) obtain informed consent from developing a versatile technology platform to potentially subjects, c) permit the device to be used only with subjects provide solutions in additional diagnostic and therapeutic under the investigator’s supervision, d) report adverse reactions, markets, pending FDA approval. NorthStar Medical e) keep accurate records, and, f) more generally, to conduct Radioisotopes is headquartered in Beloit, Wis. the investigation in accordance with the signed agreement with the sponsor, the investigational plan, FDA’s regulations, and whatever conditions of approval are imposed by the reviewing Nuclear Imaging Services, LLC 511 IRB or FDA. Nuclear Imaging Services, LLC is a leading provider of nuclear cardiology turnkey solutions. We provide refurbished equipment, parts, and nationwide service and clinical support Royal Philips 110 for SPECT, PET, and PET/CT imaging. Royal Philips (NYSE: PHG, AEX: PHIA) is a leading health technology company focused on improving people’s health and enabling better outcomes across the health continuum Nuclear Medicine Technology Certification Board F002 from healthy living and prevention, to diagnosis, treatment and The NMTCB is the Nuclear Medicine Technology Certification home care. Philips leverages advanced technology and deep Board, formed for the purpose of creating and maintaining clinical and consumer insights to deliver integrated solutions. examinations for nuclear medicine technologists (NMTs). Since Headquartered in the Netherlands, the company is a leader in 1978, the NMTCB has offered high-quality certification exams diagnostic imaging, image-guided therapy, patient monitoring for NMTs to become Certified Nuclear Medicine Technologists and health informatics, as well as in consumer health and (CNMT). The NMTCB provides six certification programs: the home care. Philips’ health technology portfolio generated 2017 entry level CNMT credential, the post-primary NMTCB(CT) sales of EUR 17.8 billion and employs approximately 74,000 credential for computed tomography, the PET specialty employees with sales and services in more than 100 countries credential for positron emission tomography certification, the NCT specialty credential for nuclear cardiology, and the NMAA credential for NMT’s who have graduated from a recognized master’s level program as a Nuclear Medicine Advanced Associate. The sixth certification program which began in 2017, the NMTCB(RS), is a radiation safety credential specifically for nuclear medicine technologists.

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 68 EXHIBITOR LISTING

ScImage, Inc. 105 Syntermed, Inc. 100 Secure. Flexible. Accessible. ScImage’s PICOM365 Enterprise Syntermed, Inc., an Atlanta-based imaging and informatics PACS delivers secure on-demand access to all patient software company, is a global leader in providing cardiac images when and where you need them. Whether you’re and neuro solutions for SPECT and PET. Its solutions power an independent practice with no internal IT support or a over 50% of the nuclear medicine departments worldwide. multi-hospital system with specific security requirements, Signature products include Emory Toolbox™, Syntermed Live™, PICOM365 offers options for on-premise, cloud and hybrid Syntermed IDS™, SmartReport™, Synctools™, Adreview™ implementations across all imaging departments. Utilizing Tools, PETtools™, Flowtool™ and NeuroQ™. Syntermed your existing cameras, ScImage’s PICOM365 Enterprise PACS software is compatible with virtually any nuclear medicine offers tight integration with two leading nuclear cardiology workstation or PC/MAC that supports Microsoft® Windows® quantification software solutions. Image sharing, structured operating systems and is available direct or from leading reporting and comprehensive analytics optimize your OEMs, PACs vendors, and Systems Integrators. departmental workflows.

Thinking Systems Corporation 104 Siemens Healthineers 501 Thinking Systems, the recognized industry leader for providing Siemens Healthineers is committed to becoming the trusted comprehensive cloud-based enterprise PACS solutions for all partner of healthcare providers worldwide, enabling them to modalities, especially for molecular imaging, will exhibits its improve patient outcomes while reducing costs. Driven by revolutionary cloud-based PACS – TSXtreme™, which utilizes our long legacy of engineering excellence and our pioneering the latest cloud technology and Windows 64-bit platform. It approach to developing the latest advancements, we are provides comprehensive PACS functionalities for all modalities a global leader in medical imaging, laboratory diagnostics, with specialized clinical tools and hanging protocols. It enables clinical IT, and services. Siemens Healthineers is dedicated to physicians to perform diagnostic interpretation/reporting helping our partners be successful – clinically, operationally and securely from anywhere with consumer grade Internet financially – from prevention through diagnosis and treatment. connections. The comprehensive features include: PET-CT fusion, SPECT-CT fusion; nuclear cardiology processing; general nuclear medicine processing and review; cardiac PET Southwestern Imaging Systems and Service 111 processing; SPECT and PET brain processing; echocardiogram SWISS provides fully refurbished medical imaging equipment in image review and measurements; cardiac cath image review; addition to a broad range of related services for a dependable radiology image review with advanced tools. and economically smart alternative to OEM programs.

Universal Medical Resources 107 Spectrum Dynamics Medical 301 Spectrum Dynamics Medical revolutionized the practice of nuclear cardiology with the 1st clinical & commercially available Wolters Kluwer 102 CZT imaging scanner. The D-SPECT® and D-SPECT-L™ nuclear Wolters Kluwer Health company is a leading international cardiology imaging systems dramatically enhances image publisher of medical books, journals, and electronic media. quality, improves workflow, allows the ability to reduce radiation We proudly offer specialized publications and software for exposure by implementing unique low dose protocols and physicians, nurses, students and clinicians. Please visit our provides the platform for advanced imaging protocols, i.e. booth to browse our comprehensive product line. Dynamic SPECT and Simultaneous Multi Isotope.

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ASNC 2020 SEPTEMBER 24 – 27, 2020 WASHINGTON, DC Marriott Washington Wardman Park

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 70 With hereditary transthyretin-mediated (hATTR) amyloidosis... Patients and their families face ONPATTRO® (patisiran) can reverse a future of functional decline1-3 polyneuropathy manifestations of the disease4 A novel RNAi-based approach that may transform the future for your patients1,4-6 ONPATTRO is indicated for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults.

At 18 months, ONPATTRO demonstrated:

Study Design Reversal in neuropathy impairment4 The efficacy of ONPATTRO was demonstrated in • Mean change from baseline in mNIS+7 of -6.0 points a randomized, double-blind, placebo-controlled, vs 28.0 with placebo, a treatment difference of Important Safety Information multicenter clinical trial in adults with hATTR -34 points (95% CI: -39.9, -28.1; p<0.001) Infusion-Related Reactions (IRRs) Reduced Serum Vitamin A Levels and amyloidosis with polyneuropathy. Patients were 4 randomized to receive ONPATTRO 0.3 mg/kg (N=148) Improvement in quality of life In a controlled clinical study, 19% of ONPATTRO- Recommended Supplementation • Mean change from baseline in Norfolk QoL-DN treated patients experienced IRRs, compared to ONPATTRO treatment leads to a decrease in or placebo (N=77) via intravenous infusion once every 3 weeks for 18 months. score of -6.7 points vs 14.4 with placebo, a 9% of placebo-treated patients. The most common serum vitamin A levels. Supplementation at the treatment difference of -21.1 points (95% CI: symptoms of IRRs with ONPATTRO were flushing, back recommended daily allowance (RDA) of vitamin A Primary endpoint: The modified Neuropathy -27.2, -15.0; p<0.001) pain, nausea, abdominal pain, dyspnea, and headache. is advised for patients taking ONPATTRO. Impairment Score + 7 (mNIS+7) is an objective To reduce the risk of IRRs, patients should receive Patients should be referred to an ophthalmologist 304-point assessment of neuropathy that measures Reduction in autonomic symptoms6,7 cranial nerve function, muscle strength, reflexes, premedication with a corticosteroid, acetaminophen, and if they develop ocular symptoms suggestive of • Mean change from baseline in COMPASS 31 postural blood pressure, quantitative sensory testing, antihistamines (H1 and H2 blockers) at least 60 minutes vitamin A deficiency (e.g. night blindness). of -5.3 points vs 2.2 with placebo, a treatment and peripheral nerve electrophysiology. prior to ONPATTRO infusion. Monitor patients during Adverse Reactions difference of -7.5 points (95% CI: -11.9, -3.2; p<0.001) the infusion for signs and symptoms of IRRs. If an IRR The most common adverse reactions that Key secondary endpoint: The Norfolk Quality of occurs, consider slowing or interrupting the infusion. occurred in patients treated with ONPATTRO Life-Diabetic Neuropathy (QoL-DN) scale is a patient- CI=confidence interval; RNA=ribonucleic acid; RNAi=RNA interference. In the case of a serious or life-threatening IRR, the were upper respiratory tract infections (29%) and reported assessment that evaluates neuropathy in the infusion should be discontinued and not resumed. infusion-related reactions (19%). following domains: physical functioning/large fiber neuropathy, activities of daily living, symptoms, small Visit www.onpattro.com to Please see brief summary of full Prescribing fiber neuropathy, and autonomic neuropathy (score get your patients started. Information following this ad. range -4 to 136). References: 1. Ando Y, Coelho T, Berk JL, et al. Orphanet J Rare Dis. 2013; 8:31. 2. Coutinho P, Martins Select secondary endpoint: The Composite da Silva A, Lopes Lima JL, et al. Amyloid and amyloidosis: Proceedings of the Third International Symposium on Amyloidosis, Póvoa de Varzim, Portugal, 23-28 September 1979. Amsterdam: Autonomic Symptom Score 31 (COMPASS 31) Excerpta Medica; 1980:88-98. 3. Vinik EJ, Vinik AI, Paulson JF, et al. J Peripher Nerv Syst . is a patient-reported questionnaire that evaluates 2014;19:104-119. 4. ONPATTRO [package insert]. Cambridge, MA: Alnylam Pharmaceuticals, Inc; 2018. Adams D, Coelho T, Obici L, et al. Neurology. 2015;85(8):675-682. Adams D, Gonzalez-Duarte 6 autonomic domains: orthostatic intolerance, 5. 6. ONPATTRO is a registered trademark A, O’Riordan WD, et al. N Engl J Med. 2018;379(1):11-21. 7.Center for Drug Evaluation and Research. of Alnylam Pharmaceuticals, Inc. vasomotor, secretomotor, gastrointestinal, bladder, and NDA 210922—patisiran—cross-discipline team leader review. U.S. Department of Health and Human © 2019 Alnylam Pharmaceuticals, Inc. Services, Food and Drug Administration; 2018. All rights reserved. TTR02-USA-00048-052018-V2 pupillomotor (score range 0 to 100). Brief summary of Full Prescribing Information for ONPATTRO, as serum vitamin A levels do not reflect the total vitamin A In animal studies, intravenous administration of patisiran lipid ONPATTRO® (patisiran) injection—Please consult in the body. complex (patisiran-LC) to pregnant rabbits resulted in developmental Full Prescribing Information. Patients should be referred to an ophthalmologist if they develop toxicity (embryofetal mortality and reduced fetal body weight) at ocular symptoms suggestive of vitamin A deficiency (e.g., doses that were also associated with maternal toxicity. No adverse INDICATIONS AND USAGE night blindness). developmental effects were observed when patisiran-LC or a rodent- ONPATTRO is indicated for the treatment of the polyneuropathy of specific (pharmacologically active) surrogate were administered to hereditary transthyretin-mediated amyloidosis in adults. ADVERSE REACTIONS pregnant rats (see Data). Clinical Trials Experience DOSAGE AND ADMINISTRATION In the U.S. general population, the estimated background risk of major Because clinical studies are conducted under widely varying birth defects and miscarriage in clinically recognized pregnancies is Dosing Information conditions, adverse reaction rates observed in the clinical studies of ONPATTRO should be administered by a healthcare professional. 2 to 4% and 15 to 20%, respectively. The background risk of major birth ONPATTRO cannot be directly compared to rates in the clinical studies defects and miscarriage for the indicated population is unknown. ONPATTRO is administered via intravenous (IV) infusion. Dosing is of another drug and may not reflect the rates observed in practice. Data based on actual body weight. For patients weighing less than 100 kg, A total of 224 patients with polyneuropathy caused by hereditary the recommended dosage is 0.3 mg/kg once every 3 weeks. For transthyretin-mediated amyloidosis (hATTR amyloidosis) received Animal Data patients weighing 100 kg or more, the recommended dosage is ONPATTRO in the placebo-controlled and open-label clinical studies, Intravenous administration of patisiran-LC (0, 0.15, 0.50, or 1.5 mg/kg) 30 mg once every 3 weeks. including 186 patients exposed for at least 1 year, 137 patients exposed or a rodent-specific (pharmacologically active) surrogate (1.5 mg/kg) to Missed dose for at least 2 years, and 52 patients exposed for at least 3 years. In the female rats every week for two weeks prior to mating and continuing If a dose is missed, administer ONPATTRO as soon as possible. placebo-controlled study, 148 patients received ONPATTRO for up to throughout organogenesis resulted in no adverse effects on fertility If ONPATTRO is administered within 3 days of the missed dose, 18 months (mean exposure 17.7 months). or embryofetal development. continue dosing according to the patient’s original schedule; however, Upper respiratory tract infections and infusion-related reactions were Intravenous administration of patisiran-LC (0, 0.1, 0.3, or 0.6 mg/kg) if ONPATTRO is administered more than 3 days after the missed dose, the most common adverse reactions. One patient (0.7%) discontinued to pregnant rabbits every week during the period of organogenesis continue dosing every 3 weeks thereafter. ONPATTRO because of an infusion-related reaction. produced no adverse effects on embryofetal development. In a separate study, patisiran-LC (0, 0.3, 1, or 2 mg/kg), administered to Required Premedication Table 1: Adverse Reactions from the Placebo-Controlled Trial that pregnant rabbits every week during the period of organogenesis, All patients should receive premedication prior to ONPATTRO Occurred in at Least 5% of ONPATTRO-treated Patients and at Least resulted in embryofetal mortality and reduced fetal body weight administration to reduce the risk of infusion-related reactions 3% More Frequently than in Placebo-treated Patients at the mid and high doses, which were associated with maternal (IRRs) [see Warnings and Precautions (5.1)]. Each of the following ONPATTRO Placebo toxicity. premedications should be given on the day of ONPATTRO infusion Intravenous administration of patisiran-LC (0, 0.15, 0.50, or 1.5 mg/kg) at least 60 minutes prior to the start of infusion: intravenous Adverse Reaction N=148 N=77 % % or a rodent-specific surrogate (1.5 mg/kg) to pregnant rats every corticosteroid (e.g., dexamethasone 10 mg, or equivalent); week throughout pregnancy and lactation resulted in no adverse oral acetaminophen (500 mg); intravenous H1 blocker (e.g., Upper respiratory tract 29 21 developmental effects on the offspring. diphenhydramine 50 mg, or equivalent); and intravenous H2 blocker infectionsa (e.g., ranitidine 50 mg, or equivalent). Infusion-related reactionb 19 9 Lactation For premedications not available or not tolerated intravenously, Dyspepsia 8 4 Risk Summary equivalents may be administered orally. There is no information regarding the presence of ONPATTRO in Dyspneac,d 8 0 For patients who are tolerating their ONPATTRO infusions but human milk, the effects on the breastfed infant, or the effects on milk experiencing adverse reactions related to the corticosteroid Muscle spasmsc 8 1 production. The developmental and health benefits of breastfeeding premedication, the corticosteroid may be reduced by 2.5 mg Arthralgiac 7 0 should be considered along with the mother’s clinical need for increments to a minimum dose of 5 mg of dexamethasone Erythemac 7 3 ONPATTRO and any potential adverse effects on the breastfed infant (intravenous), or equivalent. from ONPATTRO or from the underlying maternal condition. Bronchitise 7 3 Some patients may require additional or higher doses of one or In lactating rats, patisiran was not detected in milk; however, the more of the premedications to reduce the risk of IRRs [see Warnings Vertigo 5 1 lipid components (DLin-MC3-DMA and PEG2000-C-DMG) were present and Precautions (5.1)]. aIncludes nasopharyngitis, upper respiratory tract infection, in milk. CONTRAINDICATIONS respiratory tract infection, pharyngitis, rhinitis, sinusitis, viral upper Pediatric Use respiratory tract infection, upper respiratory tract congestion. None. Safety and effectiveness in pediatric patients have not been bInfusion-related reaction symptoms include, but are not limited established. WARNINGS AND PRECAUTIONS to: arthralgia or pain (including back, neck, or musculoskeletal Geriatric Use Infusion-Related Reactions pain), flushing (including erythema of face or skin warm), nausea, Infusion-related reactions (IRRs) have been observed in patients abdominal pain, dyspnea or cough, chest discomfort or chest pain, No dose adjustment is required in patients ≥65 years old [see treated with ONPATTRO. In clinical studies, all patients received headache, rash, chills, dizziness, fatigue, increased heart rate or Clinical Pharmacology (12.3)]. A total of 62 patients ≥65 years of premedication with a corticosteroid, acetaminophen, and palpitations, hypotension, hypertension, facial edema. age, including 9 patients ≥75 years of age, received ONPATTRO in the placebo-controlled study. No overall differences in safety or antihistamines (H1 and H2 blockers) to reduce the risk of IRRs. c Not part of an infusion-related reaction. effectiveness were observed between these patients and younger In a controlled clinical study, 19% of ONPATTRO-treated patients d Includes dyspnea and exertional dyspnea. patients, but greater sensitivity of some older individuals cannot be experienced IRRs, compared to 9% of placebo-treated patients. e Includes bronchitis, bronchiolitis, bronchitis viral, lower respiratory ruled out. Among ONPATTRO-treated patients who experienced an IRR, 79% tract infection, lung infection. experienced the first IRR within the first 2 infusions. The frequency Hepatic Impairment of IRRs decreased over time. IRRs led to infusion interruption in 5% Four serious adverse reactions of atrioventricular (AV) heart block No dose adjustment is necessary in patients with mild hepatic of patients. IRRs resulted in permanent discontinuation of ONPATTRO (2.7%) occurred in ONPATTRO-treated patients, including 3 cases of impairment (bilirubin ≤1 x ULN and AST >1 x ULN, or bilirubin >1.0 to in <1% of patients in clinical studies. Across clinical studies, the most complete AV block. No serious adverse reactions of AV block were 1.5 x ULN) [see Clinical Pharmacology (12.3)]. ONPATTRO common symptoms (reported in greater than 2% of patients) of IRRs reported in placebo-treated patients. has not been studied in patients with moderate or severe with ONPATTRO were flushing, back pain, nausea, abdominal pain, Ocular adverse reactions that occurred in 5% or less of ONPATTRO- hepatic impairment. treated patients in the controlled clinical trial, but in at least 2% of dyspnea, and headache [see Adverse Reactions (6.1)]. One patient Renal Impairment in the ONPATTRO expanded access program had a severe adverse ONPATTRO-treated patients, and more frequently than on placebo, reaction of hypotension and syncope during an ONPATTRO infusion. include dry eye (5% vs. 3%), blurred vision (3% vs. 1%), and vitreous No dose adjustment is necessary in patients with mild or moderate floaters (2% vs. 1%). renal impairment (estimated glomerular filtration rate [eGFR] ≥30 Patients should receive premedications on the day of ONPATTRO to <90 mL/min/1.73m2) [see Clinical Pharmacology (12.3)]. ONPATTRO infusion, at least 60 minutes prior to the start of infusion [see Dosage Extravasation was observed in less than 0.5% of infusions in clinical studies, including cases that were reported as serious. Signs and has not been studied in patients with severe renal impairment or and Administration (2.2)]. Monitor patients during the infusion end-stage renal disease. for signs and symptoms of IRRs. If an IRR occurs, consider slowing symptoms included phlebitis or thrombophlebitis, infusion or or interrupting the ONPATTRO infusion and instituting medical injection site swelling, dermatitis (subcutaneous inflammation), Manufactured for: Alnylam Pharmaceuticals, Inc. management (e.g., corticosteroids or other symptomatic treatment) as cellulitis, erythema or injection site redness, burning sensation, or 300 Third Street, Cambridge, MA 02142 clinically indicated. If the infusion is interrupted, consider resuming at injection site pain. By: Ajinomoto Althea, Inc. a slower infusion rate only if symptoms have resolved. In the case of a USE IN SPECIFIC POPULATIONS 11040 Roselle Street, San Diego, CA 92121 serious or life-threatening IRR, the infusion should be discontinued and Pregnancy not resumed. ONPATTRO is a registered trademark of Alnylam Pharmaceuticals, Inc. Risk Summary © 2019 Alnylam Pharmaceuticals, Inc. All rights reserved. Some patients who experience IRRs may benefit from a slower TTR02-USA-00040-112018 infusion rate or additional or higher doses of one or more of the There are no available data on ONPATTRO use in pregnant women to premedications with subsequent infusions to reduce the risk of IRRs inform a drug-associated risk of adverse developmental outcomes. [see Dosage and Administration (2.2)]. ONPATTRO treatment leads to a decrease in serum vitamin A levels, and vitamin A supplementation is advised for patients Reduced Serum Vitamin A Levels and taking ONPATTRO. Vitamin A is essential for normal embryofetal Recommended Supplementation development; however, excessive levels of vitamin A are associated ONPATTRO treatment leads to a decrease in serum vitamin A with adverse developmental effects. The effects on the fetus of levels. Supplementation at the recommended daily allowance of a reduction in maternal serum TTR caused by ONPATTRO and of vitamin A is advised for patients taking ONPATTRO. Higher doses than vitamin A supplementation are unknown [see Clinical Pharmacology the recommended daily allowance of vitamin A should not be given (12.2), Warnings and Precautions (5.2)]. to try to achieve normal serum vitamin A levels during treatment with

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Brian G. Abbott, MD, MASNC Daniel S. Berman, MD, MASNC Paul Cremer, MD Raymond J. Gibbons, MD, MASNC RI and Miriam Hospital Cedars-Sinai Medical Center Cleveland Clinic Foundation Mayo Clinic Providence, RI Los Angeles, CA Shaker Heights, OH Rochester, MN United States United States United States Aiden Abidov, MD, PhD Wayne State University Ron Blankstein, MD, FASNC Sarah Cuddy, MB ChB Alessia Gimelli, MD West Bloomfield, MI Brigham & Women’s Hospital Brigham & Women’s Hospital University of Pisa United States Boston, MA Boston, MA Pisa United States United States Italy Omar F. Abouezzeddine, MD, CM, MS Mayo Clinic Stephen A. Bloom, MD, FASNC Robert A. deKemp, PhD Javier A. Gomez Valencia, MD Rochester, MN Midwest Heart and Vascular Associates University of Ottawa Heart Institute John H. Stroger Jr. Hospital United States Overland Park, KS Ottawa, ON Chicago, IL United States Canada United States Niti R. Aggarwal, MD, FASNC UW Health Robert Bober, MD Ernest G. DePuey, MD, MASNC K. Lance Gould, MD Madison, WI Ochsner Heart and Vascular Mount Sinai St. Luke’s Hospital University of Texas Medical School United States New Orleans, LA New York, NY Houston, TX United States United States United States Firas Al Badarin, MD, FASNC Prairie Heart Institute of Southern Illinois John Bois, MD Marcelo Di Carli, MD, FASNC Robert J. Gropler, MD, MASNC Carbondale, IL Mayo Clinic Brigham & Women’s Hospital Washington University United States Rochester, MN Boston, MA St. Louis, MO United States United States United States Erick Alexanderson, MD Instituto Nacional de Cardiologia Sabahat Bokhari, MD, FASNC Joseph Dietz, CNMT Gabriel B. Grossman, MD, PhD, FASNC Mexico City Columbia University Medical Center UPMC Cardiovascular Institute Hospital Moinhos de Vento Mexico Green Brook, NJ Pittsburgh, PA Porto Alegre United States United States Brazil Ahmed Aljizeeri, MB BS, FASNC King Abdulaziz Cardiac Center Camille S. Bonta Sanjay Divakaran, MD Fadi G. Hage, MD, MASNC Riyadh Summit Health Care Consulting Brigham & Womens Hospital University of Alabama at Birmingham Saudi Arabia Washington, DC Boston, MA Vestavia, AL United States United States United States Mouaz H. Al-Mallah, MD, MSc, FASNC Houston Methodist DeBakey Heart & Jamieson M. Bourque, MD, MHS, Sharmila Dorbala, MD, MPH, FASNC Christopher L. Hansen, MD, FASNC Vascular Center FASNC Brigham and Women’s Hospital Jefferson Heart Institute Houston, TX University of Virginia Health Systems Boston, MA Philadelphia, PA United States Charlottesville, VA United States United States United States Karthikeyan Ananthasubramaniam, Rami Doukky, MD, FASNC Matthew E. Harinstein, MD, FASNC MD, FASNC Paco E. Bravo, MD Cook County Health and Hospitals UPMC Heart and Vascular Institute Henry Ford Hospital University of Pennsylvania System Pittsburgh, PA Detroit, MI Philadelphia, PA Chicago, IL United States United States United States United States Gary V. Heller, MD, PhD, MASNC James A. Arrighi, MD, MASNC Chiara Bucciarelli-Ducci, MD, PhD Regina S. Druz, MD, FASNC Morristown Medical Center Rhode Island Hospital Bristol Heart Institute, University St. Francis Hosp. Catholic Health Svc New Haven, CT Providence, RI Hospitals Bristol NHS Foundation Trust of LI United States United States Bristol Roslyn, NY Robert C. Hendel, MD, MASNC United Kingdom United States Asim Khan Babar, MD Tulane University School of Medicine McGovern Medical School Renee Bullock-Palmer, MD, FASNC W. Lane Duvall, MD, FASNC New Orleans, LA Houston, TX Deborah Heart and Lung Hospital Hartford Hospital United States United States Browns Mills, NJ Hartford, CT Thomas A. Holly, MD, FASNC United States United States Danny A. Basso, CNMT, NCT Northwestern University University Hospital Dennis A. Calnon, MD, MASNC Andrew J. Einstein, MD, PhD, FASNC Chicago, IL Augusta, GA OhioHealth Heart & Vascular Physicians Columbia University Medical Center United States United States Columbus, OH New York, NY Edward Hulten, MD, MPH, FASNC United States United States Timothy M. Bateman, MD, MASNC Walter Reed National Military Medical St. Luke’s Mid America Heart Institute James A. Case, PhD, FASNC Parham Eshtehardi, MD Center Kansas City, MO Cardiovascular Imaging Technologies Atlanta, GA Bethesda, MD United States Kansas City, MO United States United States United States Jeroen J. Bax, MD, PhD, FASNC Kathleen B. Flood Fabien Hyafil, MD, PhD Leiden University Medical Center Manuel D. Cerqueira, MD, MASNC American Society of Nuclear Cardiology Hopitaux de Paris Leiden Cleveland Clinic Foundation Fairfax, VA Paris Netherlands Cleveland, OH United States France United States Rob S.B Beanlands, MD, FASNC Ernest V. Garcia, PhD, MASNC Mark C. Hyun, CNMT, NCT, RT(N)(R), University of Ottawa Heart Institute Panithaya Chareonthaitawee, MD Emory University Hospital FASNC Ottawa, ON Mayo Clinic Atlanta, GA Cedars-Sinai Medical Center Canada Rochester, MN United States Los Angeles, CA United States United States George A. Beller, MD, MASNC Myron C. Gerson, MD, MASNC University of Virginia Health System Benjamin Chow, MD, FASNC University of Cincinnati Medical Center Ami E. Iskandrian, MD, PhD, MASNC Charlottesville, VA University of Ottawa Heart Institute Cincinnati, OH University of Alabama at Birmingham United States Ottawa, ON United States Birmingham, AL Canada United States

#ASNC2019 /myASNC @myASNC American Society of Nuclear Cardiology 74 ASNC2019 FACULTY continued

Wael A. Jaber, MD Jamshid Maddahi, MD, FASNC Khurram Nasir, MD, MPH Mehran Sadeghi, MD Cleveland Clinic Foundation David Geffen School of Medicine at Yale School of Medicine Yale Unviersity Cleveland, OH UCLA New Haven, CT New Haven, CT United States Los Angeles, CA United States United States United States Diwakar Jain, MD, MASNC Danilo Neglia, MD, PhD Ibrahim M. Saeed, MD Westchester Medical Center John J. Mahmarian, MD, MASNC Fondazione Toscana Gabriele St. Luke’s Mid America Heart Institute Valhalla, NY Methodist DeBakey Cardiology Monasterio Kansas City, MO United States Associates Pisa United States Houston, TX Italy Scott D. Jerome, DO, FASNC Habib Samady, MD United States University of Maryland School of Robert A. Pagnanelli, CNMT, RT(N)(R), Emory School of Medicine Medicine Maryam Mahmood, MD NCT, FASNC Atlanta, GA Westminster, MD Mayo Clinic Duke University Medical Center United States United States Rochester, MN Hillsborough, NC Rupa Mehta Sanghani, MD, FASNC United States United States Constance M. Johnson, PhD, RN Rush University Medical Center The University of Texas Health Science Saurabh Malhotra, MD, MPH, FASNC Shivda Pandey, MD Chicago, IL Center at Houston University of Buffalo Boston Medical Center United States Houston, TX Buffalo, NY Boston, MA Thomas H. Schindler, MD United States United States United States Johns Hopkins University Geoffrey Johnson, MD, PhD April Mann, MBA, CNMT, RT(N), NCT, Amit R. Patel, MD Baltimore, MD Mayo Clinic MASNC University of Chicago United States Rochester, MN Hartford Hospital Chicago, IL Eric J. Schockling, CNMT United States South Hadley, MA United States Norton Cardiovascular Diagnostics United States Nils P. Johnson, MD Krishna K. Patel, MD Lanesville, IN University of Texas Medical School at Ahmad Masri, MD St. Luke’s Mid America Heart Institute United States Houston University of Pittsburgh Medical Center Kansas City, MO Ronald G. Schwartz, MD MS, MASNC Houston, TX Pittsburgh, PA United States University of Rochester Medical Center United States United States Lawrence M. Phillips, MD, FASNC Rochester, NY Hayan Jouni, MD Samia Massalha, MD NYU School of Medicine United States Mayo Clinic University of Ottawa Heart Institute New York, NY Maria G. Sciammarella, MD Rochester, MN Ottawa, ON United States UCSF United States Canada Donna M. Polk, MD, MPH, FASNC San Francisco, CA Philipp A. Kaufmann, MD A. Iain McGhie, MD Brigham & Women’s Hospital United States University Hospital Zurich St. Luke’s Mid America Heart Institute Boston, MA Senthil Selvaraj, MD Zurich Kansas City, MO United States Penn Medicine Switzerland United States Indu Poornima, MD Philadelphia, PA Marla C. Kiess, MD Denise A. Merlino, CPC, MBA, CNMT Allegheny General Hospital United States St. Paul’s Hospital Merlino Healthcare Consulting Corp. Pittsburgh, PA Nishant Shah, MD, MPH, FASNC Vancouver, BC Gloucester, MA United States Alpert Medical School of Brown Canada United States Athena Poppas, MD University Georgia Lawrence, JD Jennifer H. Mieres, MD, MASNC RI and Miriam Hospital Providence, RI ASNC North Shore — Long Island Jewish Providence, RI United States Fairfax, VA Health System Thomas P. Power, MD Albert J. Sinusas, MD, FASNC United States Lake Success, NY AIM Specialty Health Yale University School of Medicine United States Viet Le, PA-C Chicago, IL New Haven, CT Intermountain Medical Center Edward J. Miller, MD, PhD, FASNC United States United States Salt Lake City, UT Yale University Joe Reyes Hicham Skali, MD United States New Haven, CT ASNC Brigham & Womens’ Hospital United States Daniel Lenihan, MD Fairfax, VA Boston, MA Washington University School of Todd D. Miller, MD, MASNC United States United States Medicine in St. Louis Mayo Clinic Frederick L. Ruberg, MD Piotr J. Slomka, PhD St. Louis, MO Rochester, MN Boston University School of Medicine Cedars-Sinai Medical Center United States United States Boston, MA Los Angeles, CA Jeffrey A. Leppo, MD, MASNC William R. Miranda, MD United States United States Berkshire Medical Center Mayo Clinic Terrence D. Ruddy, MD, FASNC Gary R. Small, MD Pittsfield, MA Rochester, MN University of Ottawa Heart Institute Ottawa Heart Institute United States United States Ottawa, ON Ottawa, ON Rafael Lopes, MD, PhD Venkatesh L. Murthy, MD, PhD, FASNC Canada Canada Hospital do Coracao University of Michigan Raymond R. Russell III, MD, PhD, Prem Soman, MD, PhD, MASNC Sao Paolo Ann Arbor, MI MASNC UPMC Heart and Vascular Institute Brazil United States Rhode Island Hospital Pittsburgh, PA Maria L. Mackin, CNMT, RT, RT(N) Fernando Mut, MD Providence, RI United States University of Rochester Spanish Association Hospital United States Brett W. Sperry, MD Rochester, NY Montevideo St. Luke’s MidAmerica Heart United States Uruguay Kansas City, MO United States

75 www.asnc.org/ASNC2019 ASNC2019 FACULTY continued

Raghunandan Dudda Subramanya, Mark Travin, MD, MASNC R. Parker Ward, MD, FASNC David G. Wolinsky, MD, MASNC MD, FASNC Montefiore Medical Center University of Chicago Medical Center Cleveland Clinic Florida Virtua Cardiology Group Bronx, NY Chicago, IL Weston, FL Voorhees, NJ United States United States United States United States James E. Udelson, MD, MASNC Jaime Warren, CNMT, MBA Clyde W. Yancy, MD Balaji K. Tamarappoo, MD, PhD Tufts-New England Medical Center Norton Healthcare Northwestern University Cedars Sinai Medical Center Boston, MA Louisville, KY Chicago, IL Los Angeles, CA United States United States United States United States William A. Van Decker, MD, MASNC Janet Wei, MD Keiichiro Yoshinaga, MD, PhD, FASNC Ahmed Tawakol, MD Temple University Hospital Cedars-Sinai National Institute Radiological Science Massachusetts General Hospital Philadelphia, PA West Hollywood, CA Chiba Waltham, MA United States United States Japan United States Vikas Veeranna, MD Richard Weinberg, MD, PhD, FASNC Weihua Zhou, PhD Gregory S. Thomas, MD, MPH, MASNC Berkshire Medical Center University of Michigan University of Southern Mississippi Long Beach Memorial Medical Center Pittsfield, MA Ann Arbor, MI Hattiesburg, MS Long Beach, CA United States United States United States United States Hein J. Verberne, MD, PhD R. Glenn Wells, PhD Randall C. Thompson, MD, FASNC Academic Medical Center University of Ottawa Heart Institute St Luke’s Mid America Heart Institute Amsterdam Ottawa, ON Kansas City, MO Netherlands Canada United States Annabelle Volgman, MD Kori T. Wilcox, RN Peter Tilkemeier, MD, MASNC Rush University Mayo Clinic Greenville Health System Chicago, IL Rochester, MN Greenville, SC United States United States United States Sarah Voll, ACNP-BC Kim A. Williams Sr., MD, MASNC Julius Torelli, MD Rush Medical College Rush University School of Medicine eviCore Healthcare Chicago, IL Chicago, IL Franklin, TN United States United States United States

Nuclear Best Practices for Today, Cardiology Innovations for Tomorrow Today April 17-19, 2020 2020 The Ritz-Carlton, Tysons Corner, McLean, VA Don’t miss this two-and-a-half day interactive course for physicians, technologists and other healthcare professionals that provides the latest updates in nuclear cardiology imaging. ASNC designates this live activity for AMA PRA Category 1 Credits™ for physicians, and ARRT Category A credits for technologists.

www.asnc.org/nctoday

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 76 AUTHOR/FACULTY INDEX

Abbott, Brian, CM-03, IM-05, TB-04, 310 Cho, Sang-Geon, 100-02, 201-05 Hage, Fadi, IM-04 Abidov, Aiden, TB-01 Chong, Aun-Yeong, 101-02 Hagio, Tomoe, 101-04, 101-05, 210-02 Abikhzer, Gad N., 222-01 Chow, Benjamin, CM-03, IM-02, IM-05 Han, Jinah, 210-03 Abouezzeddine, Omar, CM-02, PL-04 Chua, Terrance Siang Jin, 102-01 Hanson, Christopher A., 202-03, TB-01 Aggarwal, Niti, SOME-01, SOME-02 Churchill, Timothy W., 100-01 Hansen, Jonathan, 310-05 Agoston, Ildiko, 202-02 Clemmensen, Tor S., 310-02 Harb, Serge, 310-05 Ahmadi, Ali, 301-01 Cooke, Charles D., 321-04 Harel, François, 222-01 Ahmed, Amjad, 301-05, 322-02 Cooke, David, 100-06, 210-05 Harinstein, Matthew, 100 Ahmed, Dalia, 301-05, 322-02 Corbett, James R., 101-04, 101-05, 210-02, 301-02 Harland, Daniel R, 302-02, 322-03 Al Badarin, Firas, CM-04, CM-05, TB-04 Cosgrove, Kelly P., 210-03 Harms, Hendrik J., 301-03, 310-02, 310-03 Al’Aref, Subhi J., 201-01, 201-02 Cremer, Paul, CA-04, IM-02, IM-04, PET-01, 310-05 Harper, Glenn, 322-04 Alali Alfaris, Mousa, 301-05, 322-02 Cuddy, Sarah, CM-01, SOME-03, 221-04 Hawley, Christi, 101-01 Alavi, Abass, 222-02, 222-03, 322-05 Cuero, Jose, 102-03 Hayes, Sean W., 201-03 Alexanderson, Erick, PET-03, 102 Curran, Sean, 322-04 Hazel-Dabagian, Janet, 322-04 Alharbi, Ibrahim, 322-02 Darlington, Andrew T., 221-03 He, Zhuo, 202-06 Alharthi, Mohsen, 301-05, 322-02 Datseris, Ioannis, 102-05 Heald, Gary, 201-04, 321-03 Aljizeeri, Ahmed, IM-01, 301-05, 322-02 Davies, Daniel, 202-04 Heller, Gary V., PET-04, SAT-05, TB-01, 322-04, 310 Al-Mallah, Mouaz, CA-02, Lab-01, PET-01, PET-02, PET- Day, Francis, 322-04 Hendel, Robert, A-02, POL-01, WL-02 04, 301-05, 322-02 DeFilippis, Ersilia M., 100-01 Hillmer, Ansel T., 210-03 Alraies, M. Chadi, SOME-03 deKemp, Robert, PET-04, PL-03, 101-02, 301-01, 210 Hirschfeld, Cole B., 310-01 Alsaileek, Ahmed, 301-05, 322-02 Delgado Espejel, Lilian, 302-06 Hoilund-Carlsen, Poul, 222-03, 322-05 Amor, Martin M., 202-07 Demers, Krista A., 321-02 Holly, Thomas, TT-04 Ananthasubramaniam, Karthikeyan, TB-04, TT-01, DePuey, Ernest, TB-01 Holmes, Thomas W., 210-05 102-08 Dhruva, Nimish, 221-03 Hsu, Bailing, 321-05 Anderson, Jeffrey L., 301-04, 302-05 Di Carli, Marcelo, CM-03, PL-03, SAT-05, 100-01, 221-04, Huang, Yiyun, 101-01 Arani, Leila, 222-03 310-03, 101 Huang, Zijuan, 102-01 Araujo, Tiago, 100-03 Dietz, Joseph, TB-03 Hubers, David, 301-02 Arrighi, James, WL-01, 310 Divakaran, Sanjay, CA-01, 100-01, 310-03 Hulten, Edward, IM-03 Asif, Talal, 100-03 Dondi, Maurizio, 310-01 Hyafil, Fabien, CA-03, CM-04 Auerbach, Adam, 202-07 Dorbala, Sharmila, CM-02, PL-02, PL-04, POL-02, 100- Hyun, Mark, TT-01, TT-04. 201-03 Avendano, Ricardo, 101-01 01, 221-04, 310-03 Immordino, Laura, 322-04 Azab, Sahar H. A., 202-01 Doukky, Rami, IM-05, Lab-01, SAT-05, WL-01, 100-03 Inkster, James, 101-01 Babar, Asim, A-01, 310-04 Druz, Regina, SOME-02 Iskandrian, Ami, SPC-01, TB-03 Badran, André V., 221-02 Dudda Subramanya, Raghunandan, CM-02 Jaber, Wael A., CA-04, IM-02, SPC-05, 310-05 Bahl, Ajay, 102-04, 102-13 Duvall, W. Lane, CM-01, CM-03, 102-10, 201-04, 221-01, Jain, Diwakar, TT-02, 100 Balakumaran, Kathir, 102-10 222-05, 321-02, 321-03 Jerome, Scott, TT-03 Baron, Tomasz, 301-03 Einstein, Andrew J., SPC-02, 310-01 Johansson, Edvin, 100-04 Barros-Filho, Antonio C. Leite., 221-02 Eisenberg, Evann, 201-03 Johnson, Constance, A-01 Baskaran, Lohendran, 201-01, 201-02 El Yaagoubi, Yacine, 321-01 Johnson, Geoffrey, IM-04 Basso, Danny, TT-01, TT-02 Elneama, Awadelkarim, 301-05, 322-02 Johnson, Nils, A-01, PL-03 Bateman, Timothy, A-02, CA-06, SAT-05, 310 Emery, Paul, 101-01 Johnson, Ysanne, 102-09 Bax, Jeroen, A-02, PL-05, SOME-02 Englert, Joseph, 302-01, 302-04 Joshi, Saurabh, 102-10 Beanlands, Rob, IM-03, PL-02, SPC-01, SPC-04, 101-02, Engström, Mathias, 100-04 Jouni, Hayan, CM-01 301-01 Eppes, Richard, 321-04 Juneau, Daniel, 222-01 Beller, George, A-01, A-02, IM-01 Escolero, Sylvia, 301-02 Jung, Jae-joon, 210-04 Berman, Daniel, IM-01, TT-03, 201-03 Eshtehardi, Parham, SOME-01 Kang, Sae-Ryung, 201-05 Better, Nathan, 310-01 Esterlis, Irina, 210-03 Karki, Roshan, 100-05 Beyth, Rebecca J., 102-12 Estrada, Luis, 102-03 Karthikeyan, Ganesan, 310-01 Bhardwaj, Aishwarya, 102-06 Ethington, Jon-David, 301-04, 302-05 Kates, Malcolm M., 102-12 Bhatia, Anmol, 102-04, 102-13 Falk, Janelle, 322-03 Kattel, Sharma, 100-05 Bhave, Neetal, 222-04 Falk, Rodney, 221-04 Kaufmann, Philipp, PET-03 Bibbo, Courtney, 310-03 Fang, Wei, 321-05 Kaur, Komalpreet, 102-04, 102-13, 202-05 Biswas, Santanu, 301-04, 302-05 Farea, Jabir, 301-05, 322-02 Keng, Felix Yung Jih, 102-01 Blankstein, Ron, CA-01, CM-05, IM-03, 100-01, 221-04, Feher, Attila, 102-07 Kero, Tanja, 100-04 310-03, SOME-02 Felchner, Zachary, 101-01 Khadwal, Alka, 102-04, 102-13 Bloom, Stephen, CM-04, SPC-02 Feng, Qi, 102-08 Khan, Aazib, 202-02 Bober, Robert, PET-04, 302-01, 302-04 Fernandez, Stanley, 100-05 Kiess, Marla, PL-04 Bois, John, CM-05, IM-03 Ficaro, Edward P., 101-04, 101-05, 210-02, 301-02 Kijewski, Marie F., 221-04 Bokhari, Sabahat, CM-02, PET-01, TT-03 Figueiredo, Geraldo L., 221-02 Kim, Beom Soo, 202-07 Bom, Henry H., 201-05 Fisher, John, 322-04 Kim, Jahae, 100-02, 201-05 Bonta, Camille, POL-03 Flachskampf, Frank A., 301-03 Kitkungvan, Danai, 310-04 Boodagh, Parnaz, 210-04 Flood, Kathleen B., PL-02 Kitt, Therese, 102-08 Borges, Nyal, 310-05 Folks, Russell, 100-06 Knight, Stacey, 301-04, 302-05 Bourque, Jamieson, M., CM-02, PET-01, 102-11, 202-03, Freiburger, Nick K., 301-02 Knowlton, Kirk, 301-04, 302-05 222 Friedman, John D., 201-03 Konerman, Matthew C., 102-02 Boutagy, Nabil E., 102-07 Galazka, Patrycja Z, 302-02, 322-03 Kostkiewicz, Magdalena, 222-07 Bravo, Paco, CM-04 Gallegos, Cesia, 101-03 Kramer, Howard, 322-04 Bucciarelli-Ducci, Chiara, IM-05, PL-05, SOME-01 Garcia, Ernest V., A-03, SPC-03, 100-06, 210-05, 321-04 Krumholz, Harlan, 102-14 Bullock-Palmer, Renee, SOME-01, SOME-02, SOME-03, Gardner, Kimberly, 301-01 Kukreja, Gunjan, 210-04 SPC-05 Gerlach, Jim, 321-02 Kumar, Anirudh, SPC-05 Burg, Matthew, 102-09 Gerson, Myron, A-03, CM-01 Kvasic, Jessica A., 302-03 Calnon, Dennis, CM-01, POL-03, SAT-05, 102 Giannopoulou, Chariklia, 102-05 Kwon, Seong Young, 201-05 Campbell, Laurel B., 310-03 Gibbons, Raymond, A-03, IM-01 Labaree, David, 101-01 Case, James, A-03, PL-03, 210 Gimelli, Alessia, CA-03 Lara, Kyla, 321-02 Cerqueira, Manuel, IM-01, PET-02, PET-04, PL-02, TB-01 Golbazi, Arvene, 210-04 Lawrence, Georgia, POL-03 Chan, Nicholas, 202-07 Gomez Valencia, Javier, SOME-02, TB-03, 100-03 Le, Viet, SOME-01, 301-04, 302-05 Chandhok, Sheetal, 322-04 Gomez, Veronica, 102-03, 302-06 Lee, Benjamin C., 201-01, 201-02 Chareonthaitawee, Panithaya, PET-01, PL-01, PL-02, Gona, Kiran B., 210-04 Lee, Shin Rong, 101-01 TB-02 Gould, K. Lance, PET-02, PET-03, SAT-08, 310-04 Lenihan, Daniel, PL-04 Chaudhry, Waseem, 102-10 Grégoire, Jean, 222-01 Leppo, Jeffrey, SPC-02, WL-02 Chen, Kevin, 102-07 Gropler, Robert, A-02, PL-05, 210 Li, Chunxiang, 202-06 Chierice, João R. Abbud., 221-02 Grossman, Gabriel, TB-02 Li, Dianfu, 202-06 Cho, Jae Yeong, 100-02 Gulati, Martha, SOME-01, SOME-02 Li, Jianming, 321-05

77 www.asnc.org/ASNC2019 AUTHOR/FACULTY INDEX continued

Liao, Steve L., 321-02 Pershwitz, Gene, 102-10, 201-04, 321-03 Spatz, Erica, 101-03 Lichtenstein, Meir, 222-06 Philip, Benita, SPC-05, 201 Sperry, Brett, PET-01 Lima-Filho, Moyses O., 221-02 Philippe, Laurent, 321-01 Stambler, Bruce S., 221-03 Lin, Fay Y., 201-01, 201-02 Phillips, Lawrence, CM-01, 201 Stavrou, Petros Z., 102-05 Liu, Chi, 102-07, 210-03 Piccinelli, Marina, 100-06 Steers, John, 322-04 Liu, Hui, 210-01 Pieper, Justin, 301-02 Stendahl, John, 102-07 Liu, Yi-Hwa, 101-03, 210-01 Pintya, Antonio O., 221-02 Stewart, Merrill H., 302-01, 302-04 Lopes, Rafael, CM-02 Poitrasson-Rivière, Alexis, 101-04, 101-05, 210-02, Stuijfzand, Wijnand, 201-01, 201-02 Lubberink, Mark, 100-04, 301-03 301-02 Suliman, Ihab, 301-05, 322-02 Mackin, Maria L., TB-03, TT-04, 221-05 Polin, Nichole, 302-01, 302-04 Tadeo, Glenn, 201-04, 321-03 Maddahi, Jamshid, PET-04 Polk, Donna, PET-02, SOME-02 Tam, Marty C., 102-02 Mahlum, Debra, 302-02, 322-03 Polsani, Venkateshwar, 221-03 Tamarappoo, Balaji K., 201-03, CM-05 Mahmarian, John, CA-02, PL-02 Polytarchou, Kali, 102-05 Tang, Haipeng, 202-06 Mahmood, Maryam, CM-05, IM-04 Poornima, Indu, PL-03 Tang, Jing, 101-04 Makaryus, John N., 202-07 Poppas, Athena, PL-03 Taqueti, Viviany R., 100-01, 221-04, 310-03 Malecki, Monica, 322-01 Port, Steven C, 302-02, 322-03 Tawakol, Ahmed, PET-01, PL-05 Malhotra, Saurabh, TB-01, TB-03, 100-03, 100-05, Posada, Edith, 101-03 Thomas, Gregory S., 201-01, 201-02, IM-05, SPC-02, 102-06 Pourmorteza, Amir, 210-05 TT-04, 302 Maliakal, Gabriel, 201-01, 201-02 Power, Thomas, POL-02 Thompson, Randall, PET-03, POL-02, SPC-02, TT-03 Malik, Dharmender, 202-05 Prasad, Rameshwar, 222-04, 322-01 Thomson, Louise E. J., 201-03 Malm, Brian, 102-09 Prunier-Aesch, Caroline, 321-01 Thorn, Stephanie, 101-01 Mamarian, Marina, 101-01 Puente, Adriana, 102-03, 302-06 Tilkemeier, Peter, POL-02, POL-03 Mangalmurti, Sarang, 322-04 Quevedo, Federico, 201-04, 321-03 Timmerman, Nicholas, 101-02 Mann, April, POL-01, TT-02 Raggi, Paolo, 210-05 Toczek, Jakub, 210-03, 210-04 Manolis, Antonios S., 102-05 Raynor, William Y., 222-02, 222-03, 322-05 Tolbod, Lars P., 310-02 Marin-Neto, Jose A., 221-02 Régis, Claudine, 222-01 Torelli, Julius, POL-02 Martineau, Patrick, 222-01 Reyes, Joe, POL-03 Tran, Thuan, 310-03 Martinez, Carmen, 102-03, 302-06 Rizkallah, Alain, 221-01, 222-05, 321-02 Travin, Mark, CM-01 Mason, Steve, 301-04, 302-05 Rodriguez-Porcel, Martin, 202-04 Trejo-Paredes, Camila, 101-03 Masri, Ahmad, CA-05, SOME-03 Rojulpote, Chaitanya, 222-02, 222-03, 322-05 Treves, Ted, 101-01 Massalha, Samia, SOME-02, TT-02 Rosenblatt, Jeffrey A., 302-03 Udelson, James, A-01, TB-02 Mathur, Tarun, 322-04 Rosengren, Sara, 301-03, 310-02 Vadi, Shelvin K., 102-04, 102-13, 202-05 Mattei, Sheila, 102-09 Rothley, Jill, 301-02 Van Decker, William, POL-01, POL-03 McCubrey, Raymond, 301-04, 302-05 Rrapo Kaso, Elona, 102-11 van Rosendael, Alexander R., 201-01, 201-02 McGhie, A. Iain, CA-06 Ruberg, Frederick, CM-02, PL-04 Van Train, Kenneth F., 321-04 McMahon, Sean R., 221-01, 222-05, 321-03 Ruddy, Terrence, PET-02 Veeranna, Vikas, CM-04, TB-03 McPhedran, Rachel, 101-02 Russell, Raymond, PET-02, PET-03, 321 Verberne, Hein, CM-02, IM-04 Meadows, Judith L., 102-09 Rybczynski, Adam, 322-01 Virmani, Sumeet, 222-04, 322-01 Mendelson, Lawrence, 322-04 Sadeghi, Mehran M., 210-03, 210-04, IM-01, IM-03 Vitola, Joao, 310-01 Meredith, Kent, 301-04, 302-05 Sadeghi, Cirous, 100-05 Volgman, Annabelle, SOME-01 Merlino, Denise, POL-01 Saeed, Ibrahim, CM-01, IM-02 Voll, Sarah, TB-04 Mieres, Jennifer, SOME-03, SPC-02 Saha, Sudip, SPC-05 Wang, Cheng, 202-06 Miller, Edward J., A-02, PET-02, 101-03, 102-14, 210-01, Saito, Yuichi, 101-03 Wang, Lei, 321-05 221, 222 Salarian, Mani, 210-04 Ward, R. Parker, TT-04 Miller, Todd, PET-02, SPC-05 Samady, Habib, A-01 Warren, Jaime, TT-02 Min, David B., 301-04, 302-05 Sanghani, Rupa, Lab-01, SAT-03, 322-01 Wei, Janet, A-01 Min, James K., 201-01, 201-02 Saucier, Stephanie, 221-01, 222-05 Weinberg, Richard L., 101-04, 101-05, 210-02, 301-02, Minder, Michael, 301-04, 302-05 Saxena, Akansha, 102-08 CM-05, TB-02 Miranda, William, IM-02 Schenone, Aldo, 310-05 Wells, R. Glenn, TB-02 Mittal, Bhagwant R., 102-04, 102-13, 202-05 Schindler, Thomas, PET-03, PL-03, 301 Werner, Thomas J., 222-02, 222-03, 322-05, Moody, Jonathan B., 101-04, 101-05, 210-02 Schockling, Eric, TT-03 Wilcox, Kori, TB-04 Moreira, Henrique T., 221-02 Schulz, Wade, 102-14 Williams, Kim, IM-04, SOME-02 Morneau, Thomas M., 201-04, 321-03 Schwartz, Ronald G., 221-05, PET-02, TB-01 Winchester, David E., 102-12 Mourouzis, Iordanis, 102-05 Sciammarella, Maria, SPC-05, TT-01 Wolinsky, David, POL-01, POL-03 Muhlestein, Joseph B., 301-04 Selvaraj, Senthil, SPC-01 Wu, Jing, 210-01, 210-03 Murthy, Venkatesh L., 101-04, 101-05, 102-02, 210-02, Selvin, Sunil, 322-04 Wu, Kai Yi, 101-02 301-02, PET-02, 322 Seraj, Siavash, 322-05 Xu, Yanqing, 100-01, 102-08 Mut, Fernando, CM-05 Shah, Nishant, CM-04, SPC-02 Xu, Zhuoran, 201-01, 201-02 Nabulsi, Nabeel, 101-01 Sharma, Anjali, 201-04, 321-03 Yancy, Clyde, PL-01 Nagahama, Makoto, 102-06 Sharma, Ashish, 202-05 Yialamas, Maria A., 100-01 Nasir, Khurram, A-03, CM-03 Shaw, Leslee J., 201-01, 201-02 Yoo, Su Woong, 201-05 Neglia, Danilo, CA-03 Shi, Jianzhou, 202-06 Yoruk, Ayhan, 221-05 Nelson, Jacob R., 301-02 Shreves, Chris K., 301-02 Yoshinaga, Keiichiro, CM-04, TB-04 Nimke, David, 102-08 Sigman, Steven R., 221-03 Young, Bryan D., 101-03 Ogunsakin, Adebola, 100-05 Singh, Avinainder, 100-01 Yuen, Brian M., 202-07 Oliverio, Joseph G., 301-02 Singh, Gurpreet, 201-01, 201-02 Zhao, Zhongqiang, 202-06 Packard, Alan, 101-01 Singh, Jagadeesh, 222-04, 322-01 Zheng, Yumin, 321-05 Paez, Diana, 310-01 Singh, Sarbpreet, 202-05 Zhou, Weihua, SPC-03, 202-06 Pagnanelli, Robert, TT-01 Singh, Vasvi, 100-03, 221-04 Zhou, Wunan, 310-03 Palardy, Maryse, 102-02 Sinusas, Albert J., 101-01, 102-07, A-03 Pandey, Shivda, CM-04 Sivaratnam, Dinesh A., 222-06 Pandey, Mohit, 201-01, 201-02 Skali, Hicham, IM-03, 221-04 Pantos, Konstantinos, 102-05 Slomka, Piotr J., 321-02, SPC-03, 210 Park, Mi-Ae, 221-04 Small, Gary, CM-03, IM-05 Parmar, Madan, 102-04, 102-13, 202-05 Small, Aeron, 102-14 Paschke, Kelly, 310-05 Smith, Travis M., 222-05 Pascual, Thomas, 310-01 Soman, Prem, CA-05, PL-04, POL-02, SPC-01, TB-02 Patel, Amit, IM-02, PET-02 Song, Ho-Chun, 100-02, 201-05 Patel, Krishna, SPC-03 Sood, Ashwani, 102-04, 102-13, 202-05 Patel, Vaiibhav N., 102-02 (Unable to attend), 301-02 Sörensen, Jens, 100-04, 301-03, 310-02, 310-03 Pavão, Rafael B., 221-02 Soufer, Robert, 102-09 Pelletier, Diana, 201-04, 321-03 Spalding, James, 100-01, 102-08 Pelletier-Galarneau, Matthieu, 222-01 Sparks, Paul B., 222-06

#ASNC2019 @myasnc /myASNC @myASNC American Society of Nuclear Cardiology 78 SUSPECT ATTR-CM (TRANSTHYRETIN AMYLOID CARDIOMYOPATHY)

A LIFE-THREATENING DISEASE THAT CAN GO UNDETECTED

Life-threatening, underrecognized, and underdiagnosed, ATTR-CM is a rare condition found in mostly older patients in which misfolded transthyretin proteins deposit in the heart.1-7 It is vital to recognize the diagnostic clues so you can identify this disease.

CONSIDER THE FOLLOWING CLINICAL CLUES, ESPECIALLY IN COMBINATION, TO RAISE SUSPICION FOR ATTR-CM AND THE NEED FOR FURTHER TESTING

heart failure with preserved ejection fraction HFpEF in patients typically over 60 years5-7 to standard heart failure therapies INTOLERANCE (ACEi, ARBs, and beta blockers)8-10 between QRS voltage and DISCORDANCE left ventricular (LV) wall thickness11-13

of carpal tunnel syndrome DIAGNOSIS or lumbar spinal stenosis3,9,14-20 showing increased LV ECHO wall thickness6,13,16,21,22 —autonomic nervous system dysfunction- including gastrointestinal complaints or NERVOUS SYSTEM unexplained weight loss6,16,23,24

LEARN HOW TO RECOGNIZE THE CLUES OF ATTR-CM AT: SUSPECTANDDETECT.COM

References: 1. Sipe JD, Benson MD, Buxbaum JN, et al. Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 Nomenclature Guidelines. Amyloid. 2016;23(4):209-213. 2. Maurer MS, Elliott P, Comenzo R, Semigran M, Rapezzi C. Addressing common questions encountered in the diagnosis and management of cardiac amyloidosis. Circulation. 2017;135(14):1357-1377. 3. Connors LH, Sam F, Skinner M, et al. Heart failure due to age-related cardiac amyloid disease associated with wild-type transthyretin: a prospective, observational cohort study. Circulation. 2016;133(3):282-290. 4. Pinney JH, Whelan CJ, Petrie A, et al. Senile systemic amyloidosis: clinical features at presentation and outcome. J Am Heart Assoc. 2013;2(2):e000098. 5. Mohammed SF, Mirzoyev SA, Edwards WD, et al. Left ventricular amyloid deposition in patients with heart failure and preserved ejection fraction. JACC Heart Fail. 2014;2(2):113-122. 6. Maurer MS, Hanna M, Grogan M, et al. Genotype and phenotype of transthyretin cardiac amyloidosis: THAOS (Transthyretin Amyloid Outcome Survey). J Am Coll Cardiol. 2016;68(2):161-172. 7. González-López E, Gallego-Delgado M, Guzzo-Merello G, et al. Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction. Eur Heart J. 2015;36(38):2585-2594. 8. Narotsky DL, Castano A, Weinsaft JW, Bokhari S, Maurer MS. Wild-type transthyretin cardiac amyloidosis: novel insights from advanced imaging. Can J Cardiol. 2016;32(9):1166.e1-1166.e10. 9. Brunjes DL, Castano A, Clemons A, Rubin J, Maurer MS. Transthyretin cardiac amyloidosis in older Americans. J Card Fail. 2016;22(12):996-1003. 10. Castaño A, Drach BM, Judge D, Maurer MS. Natural history and therapy of TTR-cardiac amyloidosis: emerging disease-modifying therapies from organ transplantation to stabilizer and silencer drugs. Heart Fail Rev. 2015;20(2):163-178. 11. Carroll JD, Gaasch WH, McAdam KP. Amyloid cardiomyopathy: characterization by a distinctive voltage/mass relation. Am J Cardiol. 1982;49:9-13. 12. Cyrille NB, Goldsmith J, Alvarez J, Maurer MS. Prevalence and prognostic significance of low QRS voltage among the three main types of cardiac amyloidosis. Am J Cardiol. 2014;114(7):1089-1093. 13. Quarta CC, Solomon D, Uraizee I, et al. Left ventricular structure and function in transthyretin-related versus light-chain cardiac amyloidosis. Circulation. 2014;129(18):1840-1849. 14. Connors LH, Prokaeva T, Lim A, et al. Cardiac amyloidosis in African Americans: Comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis. Am Heart J. 2009;158(4):607-614. 15. Nakagawa M, Sekijima Y, Yazaki M, et al. Carpal tunnel syndrome: a common initial symptom of systemic wild-type ATTR (ATTRwt) amyloidosis. Amyloid. 2016;23(1):58-63. 16. Rapezzi C, Merlini G, Quarta CC, et al. Systemic cardiac amyloidoses: disease profiles and clinical courses of the 3 main types.Circulation . 2009;120(13):1203-1212. 17. Sperry BW, Reyes BA, Ikram A, et al. Tenosynovial and cardiac amyloidosis in patients undergoing carpal tunnel release. J Am Coll Cardiol. 2018;72(17): 2040-2050. 18. Westermark P, Westermark GT, Suhr OB, Berg S. Transthyretin-derived amyloidosis: probably a common cause of lumbar spinal stenosis. Ups J Med Sci. 2014;119(3):223-228. 19. Yanagisawa A, Ueda M, Sueyoshi T, et al. Amyloid deposits derived from transthyretin in the ligamentum flavum as related to lumbar spinal canal stenosis.Mod Pathol. 2015;28(2):201-207. 20. Sueyoshi T, Ueda M, Jono H, et al. Wild-type transthyretin-derived amyloidosis in various ligaments and tendons. Hum Pathol. 2011;42(9):1259-1264. 21. Phelan D, Collier P, Thavendiranathan P, et al. Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis. Heart. 2012;98(19):1442-1448. 22. Ternacle J, Bodez D, Guellich A, et al. Causes and consequences of longitudinal LV dysfunction assessed by 2D strain echocardiography in cardiac amyloidosis. JACC Cardiovasc Imaging. 2016;9(2):126-138. 23. Coelho T, Maurer MS, Suhr OB. THAOS - The Transthyretin Amyloidosis Outcomes Survey: initial report on clinical manifestations in patients with hereditary and wild-type transthyretin amyloidosis. Curr Med Res Opin. 2013;29(1):63-76. 24. Swiecicki PL, Zhen DB, Mauermann ML, et al. Hereditary ATTR amyloidosis: a single-institution experience with 266 patients. Amyloid. 2015;22(2):123-131.

This is a non-CME program and not part of the ASNC2019 Scientific Session as developed by the ASNC Program Committee.

ATTR-CM = transthyretin amyloid cardiomyopathy

A NEW ERA IN THE DIAGNOSIS AND TREATMENT OF ATTR-CM

JOIN US FOR THIS BREAKFAST SYMPOSIUM!

FACULTY Jamieson M. Bourque, MD, MHS University of Virginia Health System Charlottesville, VA Sabahat Bokhari, MD Columbia University Medical Center/ NewYork-Presbyterian Hospital College of Physicians and Surgeons SATURDAY, SEPTEMBER 14, 2019 | 6:30–7:45 am Columbia University New York, NY Chicago Marriott Magnificent Mile Marriott Ballroom, 4th Floor

Hot breakfast will be served at 6:15 am

Please also visit Pfizer Rare Disease at BOOTH 206 throughout the ASNC2019 Scientific Session.

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Approved applicants receive: Paid travel expenses Free registration Interactive discussions on new and eerging technologies with the leaders of nuclear cardiology APPLY BY AUGUST 31, 2019

- FACULTY - MARCELO DI CARLI, MD, HARVARD MEDICAL SCHOOL PREM SOMAN, MD, PHD, MASNC, UNIVERSITY OF PITTSURH RANDALL THOMPSON, MD, FASNC, SAINT LUKE’S HEALTH SYSTEM ASNC.ORG/FUTURELEADERS ™ We are Cardiac PET.

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