Supplemental Table 2. List of known commonly affected by radiation in each of the brain tumor cell lines as detected by microarray analysis of polysome-bound RNA. Each cell line was irradiated with 7 Gy and collected for polysome microarray analyses 6h later.

Unigene # Descripiton Fold Change (log 2) U87 SF126 SF539 Hs.429294 ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.5848 1.0814 1.1244 Hs.471461 ACSL3 Acyl-CoA synthetase long-chain family member 3 1.2423 1.5231 1.6914 Hs.268785 ACSL4 Acyl-CoA synthetase long-chain family member 4 1.5629 1.6648 1.5797 Hs.509765 ACTN1 Actinin, alpha 1 1.0011 1.1897 1.5185 Hs.393201 ACTR2 ARP2 -related 2 homolog (yeast) 1.4237 1.0457 1.8676 Hs.150402 ACVR1 activin A receptor, type I=Ser/Thr protein kinase receptor R1 1.2883 1.2529 1.3751 Hs.2442 ADAM9 A disintegrin and metalloproteinase domain 9 (meltrin gamma) 1.6789 1.3432 1.7162 Hs.498313 ADSS Adenylosuccinate synthase 1.1363 1.4457 1.2801 Hs.515053 AES Amino-terminal enhancer of split 1.5198 1.8321 2.1584 Hs.904 AGL Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen 1.251 1.5334 1.7011 debranching , glycogen storage disease type III) Hs.159118 AMD1 Adenosylmethionine decarboxylase 1 1.2026 1.8569 1.8943 Hs.494173 ANXA1 Annexin A1 1.5494 1.4971 1.7382 Hs.406191 AP3S1 Adaptor-related protein complex 3, sigma 1 subunit 2.1708 1.3507 1.4215 Hs.62578 ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 1.6497 1.7298 1.5973 (brefeldin A-inhibited) Hs.6838 ARHE Rho family GTPase 3 1.7558 1.4882 1.5214 Hs.372616 ARL1 ADP-ribosylation factor-like 1 1.0714 1.0162 1.1354 Hs.514870 ATP5F1 ATP synthase, H+ transporting, mitochondrial F0 complex, 1.3973 1.5191 1.7002 subunit b, isoform 1 Hs.429 ATP5G3 ATP synthase, H+ transporting, mitochondrial F0 complex, 1.1642 1.0829 1.4614 subunit c (subunit 9) isoform 3 Hs.533526 ATRX Alpha thalassemia/mental retardation syndrome X-linked 1.2156 1.517 1.9389 (RAD54 homolog, S. cerevisiae) Hs.55220 BAG2 BCL2-associated athanogene 2 1.2491 1.3464 1.3782 Hs.13261 BAI3 Brain-specific angiogenesis inhibitor 3 1.6229 1.6078 1.8126 Hs.513520 BCKDK Branched chain ketoacid dehydrogenase kinase 1.2289 1.3986 1.7656 Hs.489132 BET1 BET1 homolog (S. cerevisiae) 1.061 1.3097 1.0701 Hs.10136 BPHL Biphenyl hydrolase-like (serine hydrolase; breast epithelial 1.1591 1.3581 1.3721 mucin-associated antigen) Hs.499833 C10orf74 10 open reading frame 74 1.5987 1.6633 2.1496 Hs.72925 C11orf13 open reading frame 13 1.2271 1.4682 1.5697 Hs.277517 C11orf2 Chromosome 11 open reading frame2 1.3677 1.5229 1.4956 Hs.204559 C1orf9 open reading frame 9 1.1811 1.791 1.5091 Hs.369284 C20orf6 open reading frame 6 1.5456 1.2165 1.3027 Hs.485588 C6orf142 open reading frame 142 1.0101 1.659 1.1193 Hs.508524 CACYBP Calcyclin binding protein 1.146 1.2077 1.1298 Hs.85137 CCNA2 cyclin A2 1.5967 1.1623 1.2019 Hs.430646 CCNC Cyclin C 1.3018 1.1578 1.2496 Hs.13291 CCNG2 Cyclin G2 1.9092 1.0385 1.3503 Hs.485518 CD2AP CD2-associated protein 1.4586 1.7699 1.5514 Hs.334562 CDC2 Cell division cycle 2, G1 to S and G2 to M 1.8629 1.8635 1.9916 Hs.433201 CDK2AP1 CDK2-associated protein 1=putative oral tumor suppressor 1.8304 1.4776 1.402 protein (doc-1) Hs.238990 CDKN1B Cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.552 1.0068 1.018 Hs.444818 CGGBP1 CGG triplet repeat binding protein 1 1.3927 1.4676 1.8099 Hs.433732 CLK1 CLK-1=CDC-like kinase 1=PITSLRE alpha 1.3467 1.3712 1.6932 1= associated protein kinase P58/GTA Hs.311346 CMAS Cytidine monophosphate N-acetylneuraminic acid synthetase 1.1631 1.1429 1.1201 Hs.294603 CNIH Cornichon homolog (Drosophila) 1.4687 1.1157 1.0312 Hs.430075 COX7C cytochrome c oxidase subunit VIIc 1.6917 1.3904 1.2413 Hs.191219 CPNE3 Copine III 1.2704 1.7793 1.9871 Hs.13313 CREBL2 CAMP responsive element binding protein-like 2 1.3471 1.5472 1.5717 Hs.534380 CRIPT Postsynaptic protein CRIPT 1.3691 1.25 1.1616

1 Hs.83114 CRYZ Crystallin, zeta (quinone reductase) 1.5132 1.3227 1.418 Hs.181390 CSNK1G2 casein kinase I gamma 2 1.1706 1.3368 1.0717 Hs.410037 CTGF Connective tissue growth factor 1.1562 1.768 2.034 Hs.520136 CUL7 Cullin 7 1.0643 1.1098 1.1391 Hs.467662 DDEF2 Development and differentiation enhancing factor 2 1.142 1.895 1.5628 Hs.484813 DEK DEK oncogene (DNA binding) 1.4515 1.644 1.2979 Hs.323583 DKFZp434L142 Hypothetical protein DKFZp434L142 1.2131 1.7998 1.8116 Hs.549080 DPM1 Dolichyl-phosphate polypeptide 1, 1.2183 1.1294 1.7665 catalytic subunit Hs.1602 DPYD Dihydropyrimidine dehydrogenase 1.1922 1.7474 1.7907 Hs.467084 EIF4G3 Eukaryotic translation initiation factor 4 gamma, 3 1.1455 1.5355 1.6795 Hs.135646 ELF1 ELF-1=ets family transcription factor 1.4939 1.4608 2.146 Hs.46523 ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2.9246 2.0574 2.4751 Hs.76753 ENG Endoglin (Osler-Rendu-Weber syndrome 1) 2.4976 1.1955 1.4164 Hs.93659 ERP70 Protein disulfide isomerase-associated 4 1.1894 1.057 1.0085 Hs.5509 EVI2B Ecotropic viral integration site 2B 1.3678 1.1565 1.4263 Hs.434053 FAM3C Family with sequence similarity 3, member C 1.3729 1.0858 1.239 Hs.216653 FBXO9 F-box protein 9 1.2515 1.5741 1.2176 Hs.6540 FGF13 Fibroblast growth factor 13 1.4068 2.2911 1.9215 Hs.487175 FGFR1OP FGFR1 oncogene partner 1.039 1.1237 1.0912 Hs.267446 FLJ11184 Hypothetical protein FLJ11184 1.4659 1.6112 1.616 Hs.380897 FTS Fused toes homolog (mouse) 1.2809 1.2536 1.5338 Hs.3530 FUSIP1 FUS interacting protein (serine-arginine rich) 1 1.497 1.8062 2.2898 Hs.173859 FZD7 Frizzled homolog 7 (Drosophila) 1.7581 1.4054 1.3722 Hs.502244 GA17 Dendritic cell protein 1.0196 1.0441 1.2466 Hs.9701 GADD45G Growth arrest and DNA-damage-inducible, gamma 1.0964 1.1873 1.2336 Hs.127407 GALNT7 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N- 1.2663 1.9317 2.6477 acetylgalactosaminyltransferase 7 (GalNAc-T7) Hs.1691 GBE1 glucan (1,4-alpha-), branching enzyme 1 (glycogen branching 1.3845 1.4474 1.5023 enzyme, Andersen disease, glycogen storage disease type IV) Hs.546256 GCSH Glycine cleavage system protein H (aminomethyl carrier) 1.6548 1.4259 1.2372 Hs.78619 GGH Gamma-glutamyl hydrolase (conjugase, 1.4216 1.4706 1.3029 folylpolygammaglutamyl hydrolase) Hs.352656 GHITM Growth hormone inducible transmembrane protein 1.4382 1.3515 1.4292 Hs.151413 GMFB Glia maturation factor, beta 1.0785 1.6808 2.0034 Hs.73799 GNAI3 Guanine nucleotide binding protein (G protein), alpha 1.8339 1.1828 1.6953 inhibiting activity polypeptide 3 Hs.534196 GNG10 Guanine nucleotide binding protein (G protein), gamma 10 1.8313 1.2201 1.4066 Hs.344151 GOLGA4 Golgi autoantigen, golgin subfamily a, 4 1.0911 1.2202 1.1886 Hs.411881 GRB14 Growth factor receptor-bound protein 14 1.1773 1.4751 1.3688 Hs.509447 GRLF1 Glucocorticoid receptor DNA binding factor 1 1.2442 1.6065 1.1121 Hs.546259 H3F3A H3 histone, family 3A 1.1954 1.1219 1.1681 Hs.470611 HAT1 Histone acetyltransferase 1 1.5785 1.8707 1.8568 Hs.434953 HMGB2 High-mobility group box 2 1.0481 1.2158 1.2496 Hs.59889 HMGCS2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 1.0643 1.4068 1.5491 (mitochondrial) Hs.356285 HMGN1 High-mobility group nucleosome binding domain 1 1.0779 1.0037 1.0207 Hs.487774 HNRPA2B1 Heterogeneous nuclear ribonucleoprotein A2/B1 1.0385 1.5412 1.4655 Hs.527105 HNRPDL Heterogeneous nuclear ribonucleoprotein D-like 1.1322 1.0862 1.0295 Hs.412707 HPRT1 Hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan 1.2121 1.3099 1.0743 syndrome) Hs.270851 HSHIN1 HIV-1 induced protein HIN-1 1.1584 1.5853 1.7392 Hs.336046 IL13RA2 IL-13 receptor alpha2 1.2674 1.9121 1.3075 Hs.79440 IMP-3 KOC=putative RNA binding protein=IGF-II mRNA-binding 1.5822 1.1597 1.4285 protein 3 Hs.513867 ITGAE Integrin, alpha E (antigen CD103, human mucosal lymphocyte 1.3414 1.326 1.3713 antigen 1; alpha polypeptide) Hs.355722 ITGB8 Integrin beta 8 1.0681 1.5107 1.0231 Hs.409202 JAG1 Jagged 1 (HJ1)=Notch1 ligand 1.0799 1.6292 1.6847 Hs.274531 KIAA0052 Superkiller viralicidic activity 2-like 2 (S. cerevisiae) 1.2467 1.4559 1.4807 Hs.8878 KIF11 Kinesin family member 11 1.0152 1.6651 1.1438 Hs.435557 KIF5C Kinesin family member 5C 1.0305 1.1258 1.1081 Hs.376206 KLF4 GKLF=EZF=KLF4=gut-enriched Kruppel-like zinc finger 1.171 1.3999 1.2704 protein=expressed in vascular endothelial cells

2 Hs.409081 KMO Kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 1.2178 1.1857 1.1677 Hs.496684 LAMP2 Lysosomal-associated membrane protein 2 1.1818 1.4614 1.6648 Hs.23581 LEPR Leptin receptor 1.5677 1.4216 1.4351 Hs.159142 LFNG Lunatic fringe homolog (Drosophila) 1.1112 1.6549 2.2517 Hs.49787 LTBP1 Latent transforming growth factor beta binding protein 1 1.2054 1.5925 1.3879 Hs.406475 LUM Lumican 1.4766 1.766 1.7698 Hs.433332 MAP2K1IP1 Mitogen-activated protein kinase kinase 1 interacting protein 1 1.3425 1.5491 1.8231 Hs.134106 MAP2K4 mitogen-activated protein kinase kinase 1.3857 1.1937 1.5311 4=MEK4=MKK4=sek1=JNK activating kinase 1 Hs.269775 MAP3K7IP2 Mitogen-activated protein kinase kinase kinase 7 interacting 1.328 1.7146 1.5974 protein 2 Hs.432453 MAP3K8 Mitogen-activated protein kinase kinase kinase 8 1.243 1.8433 1.5476 Hs.468239 MAP4K3 Mitogen-activated protein kinase kinase kinase kinase 3 1.3213 1.2249 1.2328 Hs.519909 MARCKS Myristoylated alanine-rich protein kinase C substrate 1.3026 2.0165 1.4611 Hs.510989 MEIS2 Meis1, myeloid ecotropic viral integration site 1 homolog 2 1.2732 1.4984 1.6142 (mouse) Hs.492716 MGC21654 Unknown MGC21654 product 1.0206 1.1366 1.0962 Hs.355750 MGC5306 Hypothetical protein MGC5306 1.4457 1.1792 1.162 Hs.124165 MRPS30 Mitochondrial ribosomal protein S30 1.1026 1.4522 1.4031 Hs.440394 MSH2 MSH2=DNA mismatch repair mutS homologue 1.0043 1.1905 1.4978 Hs.481551 MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase 1.2247 1.2313 1.2713 reductase Hs.513817 MYCPBP C-myc promoter binding protein 1.1029 1.6608 1.7887 Hs.74823 NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 1.1793 1.4133 1.5618 (7.5kD, MWFE) Hs.458657 NEF3 3 (150kDa medium) 1.7859 1.256 1.1492 Hs.481181 NEK1 NIMA (never in mitosis gene a)-related kinase 1 1.1387 1.3974 1.1791 Hs.388613 NEO1 Neogenin homolog 1 (chicken) 1.0655 1.1405 1.1949 Hs.371987 NFAT5 Nuclear factor of activated T-cells 5, tonicity-responsive 1.0228 1.1836 1.128 Hs.404741 NFE2L3 Nuclear factor (erythroid-derived 2)-like 3 1.4793 1.1082 1.0895 Hs.84928 NFYB Nuclear transcription factor Y, beta 1.3025 1.6667 1.2293 Hs.3281 NPTX2 Neuronal pentraxin II 1.5977 1.4776 1.1428 Hs.347991 NR2F2 Nuclear receptor subfamily 2, group F, member 2 1.5194 1.7623 1.2771 Hs.229641 PC4 Activated RNA polymerase II transcription cofactor 4 1.0593 1.1636 1.3652 Hs.78996 PCNA PCNA=proliferating cell nuclear antigen 1.098 1.3478 1.4397 Hs.478150 PDCD10 Programmed cell death 10 1.6695 1.2621 1.3219 Hs.91747 PFN2 profilin 2 1.256 1.403 1.1351 Hs.293653 PIGK Phosphatidylinositol glycan, class K 1.284 1.039 1.0889 Hs.7037 PLDN Pallidin homolog (mouse) 1.291 1.4096 1.3963 Hs.477866 PLOD2 Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 1.237 1.2785 1.3555 Hs.496622 PLS3 Plastin 3 (T isoform) 1.228 1.5561 1.525 Hs.96 PMAIP1 APR=immediate-early-response gene=ATL-derived PMA- 1.2886 1.2218 1.0357 responsive peptide Hs.111749 PMS1 hPMS1=DNA mismatch repair protein=mutL homologue 1.0533 1.2423 1.5771 Hs.331420 PPAT Phosphoribosyl pyrophosphate amidotransferase 1.0423 1.6991 1.7379 Hs.551568 PPIL4 Peptidylprolyl isomerase (cyclophilin)-like 4 1.37 1.1234 1.4937 Hs.523302 PRDX3 Peroxiredoxin 3 1.3215 1.3318 1.3746 Hs.1908 PRG1 Proteoglycan 1, secretory granule 1.7142 1.584 1.777 Hs.280342 PRKAR1A Protein kinase, cAMP-dependent, regulatory, type I, alpha 1.3893 1.6339 1.7229 (tissue specific extinguisher 1) Hs.433068 PRKAR2B Protein kinase, cAMP-dependent, regulatory, type II, beta 1.3611 1.4791 1.0374 Hs.472010 PRNP Prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann- 1.3036 1.621 1.2896 Strausler-Scheinker syndrome, fatal familial insomnia) Hs.11776 PRPF3 PRP3 pre-mRNA processing factor 3 homolog (yeast) 1.3328 1.4992 1.219 Hs.493516 PSIP1 PC4 and SFRS1 interacting protein 1 1.574 1.9009 1.4906 Hs.368121 PSMA3 Proteasome (prosome, macropain) subunit, alpha type, 3 1.2458 1.7098 2.1722 Hs.522752 PSMD10 Proteasome (prosome, macropain) 26S subunit, non-ATPase, 1.0268 1.1187 1.6577 10 Hs.2090 PTGER2 Prostaglandin E receptor 2 (subtype EP2) 53kD 1.2727 1.4201 1.2994 Hs.61812 PTPN12 Protein tyrosine phosphatase, non-receptor type 12 1.2705 1.0927 1.1013 Hs.503860 PTS 6-pyruvoyltetrahydropterin synthase 1.5052 1.1103 1.2892 Hs.310645 RAB1A RAB1A, member RAS oncogene family 1.4087 1.4383 1.6166 Hs.369017 RAB2 RAB2, member RAS oncogene family 1.6558 1.6249 1.6445 Hs.485635 RAB23 RAB23, member RAS oncogene family 1.4432 1.3203 1.6495

3 Hs.78948 RABGGTB Rab geranylgeranyltransferase, beta subunit 1.1742 1.6802 1.8248 Hs.159087 RAD23B RAD23 (S. cerevisiae) homolog B=XPC p58 subunit 1.1888 1.2793 1.3047 Hs.79088 RCN2 Reticulocalbin 2, EF-hand calcium binding domain 1.6559 1.537 1.6327 Hs.388918 RECK Reversion-inducing-cysteine-rich protein with kazal motifs 1.3866 1.7975 1.6726 Hs.235069 RECQL RecQ protein-like (DNA helicase Q1-like) 1.131 1.6179 1.163 Hs.115474 RFC3 Replication factor C (activator 1) 3, 38kDa 1.1543 1.2005 1.1145 Hs.469199 RNF103 Ring finger protein 103 1.7686 1.3637 1.2185 Hs.508993 RNF14 Ring finger protein 14 1.0517 1.134 1.4577 Hs.292804 RNF34 Ring finger protein 34 1.6816 1.8124 1.4071 Hs.136885 RNF6 Ring finger protein (C3H2C3 type) 6 1.8289 2.3766 2.311 Hs.127219 RNGTT RNA guanylyltransferase and 5'-phosphatase 1.4856 1.3937 1.9434 Hs.75914 RNP24 Coated vesicle membrane protein 1.5365 1.493 1.0558 Hs.469264 RPIA Ribose 5-phosphate isomerase A (ribose 5-phosphate 1.1425 1.0425 1.2359 epimerase) Hs.406300 RPL23 Ribosomal protein L23 1.0132 1.5713 1.3264 Hs.119598 RPL3 Ribosomal protein L3 1.4936 1.2586 1.06 Hs.432485 RPL36A Ribosomal protein L36a 1.9083 1.4727 1.1105 Hs.446588 RPS13 Ribosomal protein S13 1.5494 1.1757 1.1351 Hs.372960 RPS21 ribosomal protein S21 1.1462 1.4569 1.6331 Hs.386384 RPS23 Ribosomal protein S23 1.3378 1.3202 1.2649 Hs.156367 RPS29 Ribosomal protein S29 1.4625 1.6216 1.031 Hs.512592 RRM2B p53R2=p53-inducible nuclear ribonucleotide 2.3307 2.133 1.5597 reductase=componant of DNA damage checkpoint pathway Hs.73088 RRP22 RAS-related on chromosome 22 1.0459 1.0695 1.0728 Hs.524809 RSN Restin (Reed-Steinberg cell-expressed - 1.1037 1.4073 1.1192 associated protein) Hs.413835 SAP30 Sin3-associated polypeptide, 30kDa 1.6385 1.5656 1.5743 Hs.427306 SBDSP Shwachman-Bodian-Diamond syndrome pseudogene 1.5985 1.1167 1.3298 Hs.200804 SDCBP Syndecan binding protein (syntenin) 1.547 1.8653 2.0659 Hs.488282 SEC61G Sec61 gamma subunit 1.1066 1.6422 1.7898 Hs.369052 SELT Selenoprotein T 1.3592 1.4827 1.825 Hs.82222 SEMA3B Sema domain, immunoglobulin domain (Ig), short basic 1.2832 1.4765 1.8188 domain, secreted, (semaphorin) 3B Hs.362728 SEP15 15 kDa selenoprotein 1.1509 1.3923 1.7214 Hs.533122 SFRS10 Splicing factor, arginine/serine-rich 10 (transformer 2 1.1267 1.2156 1.559 homolog, Drosophila) Hs.108029 SH3BGRL SH3 domain binding glutamic acid-rich protein like 1.8492 1.7329 1.3591 Hs.104315 SHOC2 Soc-2 suppressor of clear homolog (C. elegans) 1.9334 1.4975 1.3775 Hs.351571 SLC7A6 Solute carrier family 7 (cationic amino acid transporter, y+ 1.4368 1.6525 2.1778 system), member 6 Hs.75862 SMAD4 SMAD, mothers against DPP homolog 4 (Drosophila) 1.3001 1.5597 1.3478 Hs.486357 SMPDL3A Sphingomyelin phosphodiesterase, acid-like 3A 1.8441 1.4504 1.0209 Hs.529887 SMS Spermine synthase 1.1744 1.3562 1.0585 Hs.432755 SNAG1 associated golgi protein 1 1.075 1.2496 1.4951 Hs.280378 SNRPB2 Small nuclear ribonucleoprotein polypeptide B'' 1.0246 1.5028 1.1539 Hs.334612 SNRPE Small nuclear ribonucleoprotein polypeptide E 1.8907 1.6701 1.3204 Hs.105465 SNRPF Small nuclear ribonucleoprotein polypeptide F 1.1184 1.4187 1.9996 Hs.507243 SNX4 Sorting nexin 4 1.4084 1.5024 1.7156 Hs.529462 SOX30 SRY (sex determining region Y)-box 30 1.126 1.0907 1.0865 Hs.483090 SRP19 Signal recognition particle 19kDa 1.0302 1.2777 1.2614 Hs.546301 SSB Sjogren syndrome antigen B (autoantigen La) 1.1221 1.5248 1.2085 Hs.412586 STAG1 Stromal antigen 1 1.4535 1.6211 1.305 Hs.21486 STAT1 STAT1=IFN alpha/beta-responsive transcription factor ISGF3 1.2016 1.9675 1.7718 beta subunits (p91/p84) Hs.370187 STAU Staufen, RNA binding protein (Drosophila) 1.1695 1.6535 1.2794 Hs.472838 STK4 Serine/threonine kinase 4 1.1261 1.0351 1.4317 Hs.96103 TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)- 1.1275 1.3478 1.3932 associated factor, 100kDa Hs.516490 TANK TRAF family member-associated NFKB activator 1.661 1.1899 1.158 Hs.34576 TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 1.038 1.6851 1.3036 Hs.491745 TCEA1 Transcription elongation factor A (SII), 1 1.1849 1.1999 1.5572 Hs.82173 TIEG TGF-beta inducible early protein=TIEG=EGR alpha=early 1.1977 1.202 1.3898 growth response gene alpha=putative zinc finger transcription factor

4 Hs.336224 TMEFF1 Transmembrane protein with EGF-like and two follistatin-like 1.6741 1.6012 1.695 domains 1 Hs.522584 TMSB4X Thymosin, beta 4, X-linked 1.1739 1.5293 1.7693 Hs.329327 TNKS2 Tankyrase, TRF1-interacting -related ADP-ribose 1.2263 1.5208 1.7021 polymerase 2 Hs.26047 TNRC4 Trinucleotide repeat containing 4 1.0859 1.1152 1.2181 Hs.156346 TOP2A Topoisomerase (DNA) II alpha 170kDa 1.0994 1.401 1.1889 Hs.475733 TOP2B Topoisomerase (DNA) II beta 180kDa 1.038 1.1834 1.0493 Hs.490551 UBAP2L Ubiquitin associated protein 2-like 1.2069 1.1868 1.3705 Hs.385986 UBE2B Ubiquitin-conjugating enzyme E2B (RAD6 homolog) 1.5827 1.1143 1.137 Hs.145575 UBL3 Ubiquitin-like 3 1.0956 1.6088 2.1883 Hs.516217 UGP2 UDP-glucose pyrophosphorylase 2 1.0458 1.2555 1.1542 Hs.99819 USP16 Ubiquitin specific protease 16 1.2462 1.1078 1.3207 Hs.448851 USP6 ubiquitin specific protease 6 (Tre-2 oncogene)=highly similar 1.0988 1.593 1.2164 to TL132 Hs.458598 UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A 1.2945 1.233 1.0405 (yeast) Hs.436803 VBP1 Von Hippel-Lindau binding protein 1 1.1505 1.7817 1.2897 Hs.519320 VDAC1 Voltage-dependent anion channel 1 1.2624 1.92 1.2972 Hs.355927 VDAC2 Voltage-dependent anion channel 2 1.7811 1.5669 1.8888 Hs.422662 VRK1 Vaccinia related kinase 1 1.0317 1.0738 1.5676 Hs.516114 WBP1 WW domain binding protein 1 2.3913 1.0373 1.3018 Hs.98510 WDR44 WD repeat domain 44 1.4858 1.4834 1.3055 Hs.50123 ZNF189 Zinc finger protein 189 1.7905 1.4544 1.223 Hs.194718 ZNF265 Zinc finger protein 265 1.8769 1.596 1.2634 Unknown 1.2629 2.086 2.1943 Unknown 1.5064 1.7022 1.8223 Transcribed 1.2216 1.0963 1.2717 Hs.553138 Transcribed locus, strongly similar to XP_518371.1 similar to 1.6016 1.0408 1.0152 tenascin XB isoform 1; tenascin XB1; tenascin XB2; hexabrachion-like [Pan troglodytes]

Hs.388004 AHCY S-adenosylhomocysteine hydrolase -1.3865 -1.3725 -1.4449 Hs.485365 AHCYL1 S-adenosylhomocysteine hydrolase-like 1 -1.8669 -1.9516 -1.7854 Hs.19121 AP2A2 Adaptor-related protein complex 2, alpha 2 subunit -1.2509 -1.2142 -1.0978 Hs.159161 ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -1.5574 -1.1188 -1.2867 Hs.323342 ARPC4 Actin related protein 2/3 complex, subunit 4, 20kDa -1.4041 -1.2334 -1.0225 Hs.406510 ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, -1.2243 -1.0178 -1.138 beta polypeptide Hs.502842 CAPN1 Calpain 1, (mu/I) large subunit -1.6196 -1.3433 -1.3101 Hs.515371 CAPNS1 Calpain, small subunit 1 -1.0672 -1.055 -1.0603 Hs.511952 CBX6 Chromobox homolog 6 -1.4754 -2.0017 -1.9776 Hs.370921 CD151 CD151=platelet-endothelial tetraspan antigen 3 -1.1001 -1.5443 -1.0112 Hs.126688 CHDH Choline dehydrogenase -1.1938 -1.16 -1.2148 Hs.444441 CLPTM1 Cleft lip and palate associated transmembrane protein 1 -1.0038 -1.3244 -1.3087 Hs.289271 CYC1 Cytochrome c-1 -2.1137 -1.965 -1.7977 Hs.108973 DPM2 Dolichyl-phosphate mannosyltransferase polypeptide 2, -1.3445 -1.2119 -1.0143 regulatory subunit Hs.515070 EEF2 Eukaryotic translation elongation factor 2 -1.1612 -2.1626 -2.3667 Hs.433750 EIF4G1 Eukaryotic translation initiation factor 4 gamma, 1 -1.1614 -1.454 -1.2526 Hs.517145 ENO1 Enolase 1, (alpha) -1.2634 -1.9728 -1.3051 Hs.517145 ENO1 Enolase 1, (alpha) -1.4361 -1.3126 -1.4633 Hs.73875 FAH Fumarylacetoacetate hydrolase (fumarylacetoacetase) -1.3411 -1.1612 -1.1639 Hs.7768 FIBP Fibroblast growth factor (acidic) intracellular binding protein -1.2315 -1.2299 -1.3086 Hs.524183 FKBP4 FK506 binding protein 4, 59kDa -1.2505 -1.192 -1.3327 Hs.514590 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate -1.7188 -2.0484 -2.1194 Hs.518805 HMGA1 High mobility group AT-hook 1 -1.5191 -1.4247 -1.7995 Hs.162795 HSD17B2 Hydroxysteroid (17-beta) dehydrogenase 2 -1.6679 -1.4154 -1.2437 Hs.317095 IMPDH1 IMP (inosine monophosphate) dehydrogenase 1 -1.3053 -1.0053 -1.2427 Hs.265829 ITGA3 Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 -1.07 -1.3079 -1.2107 receptor) Hs.517582 MCM5 MCM5 minichromosome maintenance deficient 5, cell -1.8035 -1.2239 -1.1068 division cycle 46 (S. cerevisiae) Hs.438720 MCM7 cdc47=mcm7=minichromosome maintenance deficient (S. -1.5175 -1.6961 -1.6655

5 cerevisiae) 7 Hs.301394 MGC3101 Hypothetical protein MGC3101 -1.1837 -1.0957 -1.3179 Hs.25723 MTVR1 Mouse Mammary Turmor Virus Receptor homolog 1 -1.1025 -1.0339 -1.0806 Hs.179718 MYBL2 myb-related gene B=B-myb -1.4419 -1.3876 -1.4127 Hs.256549 NUBP2 Nucleotide binding protein 2 (MinD homolog, E. coli) -1.0252 -1.1545 -1.5728 Hs.524498 PA2G4 Proliferation-associated 2G4, 38kDa -1.1601 -1.334 -1.4511 Hs.117176 PABPN1 Poly(A) binding protein, nuclear 1 -1.5735 -1.0022 -1.3342 Hs.480311 PDLIM5 PDZ and LIM domain 5 -1.2709 -1.7397 -1.4316 Hs.329989 PLK1 Polo-like kinase 1 (Drosophila) -1.1672 -1.6257 -1.9419 Hs.465506 PPAP2C Phosphatidic acid phosphatase type 2C -1.0794 -1.011 -1.0822 Hs.240457 PPP1CA Protein phosphatase 1, catalytic subunit, alpha isoform -1.3931 -1.4808 -1.0533 Hs.11417 RABAC1 Rab acceptor 1 (prenylated) -1.6231 -1.4007 -1.0658 Hs.179735 RHOC RhoC=GTP-binding protein -1.4802 -1.4102 -1.4016 Hs.252189 SDC4 Syndecan-4 = amphiglycan = ryudocan core protein -1.38 -1.4174 -1.0961 Hs.437056 SUPT5H Suppressor of Ty 5 homolog (S. cerevisiae) -1.3424 -1.1597 -1.1409 Hs.517168 TAGLN2 Transgelin 2 -1.6046 -1.5998 -1.7768 Hs.35052 TEGT Testis enhanced gene transcript (BAX inhibitor 1) -1.4835 -1.1757 -1.2917 Hs.435609 TH Tyrosine hydroxylase -1.0475 -1.1121 -1.0969 Hs.515122 TK1 Thymidine kinase 1, soluble -1.6313 -1.6358 -1.5162 Hs.89643 TKT Transketolase (Wernicke-Korsakoff syndrome) -1.1873 -1.2219 -1.1497 Hs.26518 TM4SF7 Transmembrane 4 superfamily member 7 -1.1399 -1.0912 -1.2494 Hs.30345 TRAP1 TNF receptor-associated protein 1 -1.2209 -1.4003 -1.3188 Hs.467408 TRIM28 Tripartite motif-containing 28 -1.3059 -1.7779 -1.6395 Hs.534360 TRIP6 Thyroid hormone receptor interactor 6 -1.1871 -1.1223 -1.426

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