Human CD208 / LAMP3 (28-381, His-Tag) - Purified

OriGene Technologies, Inc. OriGene Technologies GmbH

9620 Medical Center Drive, Ste 200 Schillerstr. 5 Rockville, MD 20850 32052 Herford UNITED STATES GERMANY Phone: +1-888-267-4436 Phone: +49-5221-34606-0 Fax: +1-301-340-8606 Fax: +49-5221-34606-11 [email protected] [email protected]

AR52026PU-S Human CD208 / LAMP3 (28-381, His-tag) - Purified

Alternate names: DC-LAMP, DC-lysosome-associated membrane glycoprotein, DCLAMP, Dendritic Cell Marker, Lysosomal-associated membrane protein 3, Lysosome-associated membrane glycoprotein 3, Protein TSC403, TSC403 Quantity: 50 µg Concentration: 0.5 mg/ml (determined by absorbance at 280nm) Background: LAMP3, also known as lysosome-associated membrane glycoprotein 3, is a member of the lysosome-associated membrane protein family. LAMP3 and CD68 share very similar predicted structure. It may play a role in dendritic cell function and in adaptive immunity. Overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. Recombint human LAMP3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventiol chromatography techniques. Uniprot ID: Q9UQV4 NCBI: NP_055213 Species: Human Source: Insect cells Format: State: Liquid purified protein Purity: >90% by SDS – PAGE Buffer System: Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method) Description: AA Sequence: KAFPETRDYS QPTAAATVQD IKKPVQQPAK QAPHQTLAAR FMDGHITFQT AATVKIPTTT PATTKNTATT SPITYTLVTT QATPNNSHTA PPVTEVTVGP SLAPYSLPPT ITPPAHTTGT SSSTVSHTTG NTTQPSNQTT LPATLSIALH KSTTGQKPVQ PTHAPGTTAA AHNTTRTAAP ASTVPGPTLA PQPSSVKTGI YQVLNGSRLC IKAEMGIQLI VQDKESVFSP RRYFNIDPNA TQASGNCGTR KSNLLLNFQG GFVNLTFTKD EESYYISEVG AYLTVSDPET IYQGIKHAVV MFQTAVGHSF KCVSEQSLQL SAHLQVKTTD VQLQAFDFED DHFGNVDECS SDYTLEHHHH HH Molecular weight: 38.8 kDa (362aa) Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. General Readings: Salaun B., et al. (2004) Am J Pathol. 164:861-871. Kanao H., et al. (2005) Cancer Res. 65:8640-8645.

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20160111 1 / 2 AR52026PU-S: Human CD208 / LAMP3 (28-381, His-tag) - Purified

Pictures:

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20160111 2 / 2