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WEST VIRGINIA JOURNAL OF SCIENCE AND RESEARCH | FALL 2010

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WEST VIRGINIA RECEIVES LARGEST NSF GRANT o IN STATE HISTORY n 3 The National Science Foundation (NSF) has awarded $20 million to West Virginia’s Experimental Program to Stimulate Competitive Research (EPSCoR), marking the largest single NSF award in state history. This five-year Research Infrastructure Improvement (RII) award will boost academic research and upgrade infrastructure at West Virginia University, Marshall University, West Virginia State University and other institutions. It will be matched by $2 million from the state and $2 million from participating universities. NANOMEDICINE U.S. Senators Jay Rockefeller and Joe Manchin, governor at the time, applauded the RESEARCHER, announcement, which was made by Dr. Stephen J. Kopp, President of Marshall University, TEACHER, at the statewide STaR Symposium in Huntington. “This is about research, innovation and creating good jobs – I have every confidence that AUTHOR LEADS we will see this award intensify as faculty members are recruited, research ramps up and WVNANO new discoveries are made,” said Rockefeller, a long-time champion of EPSCoR. WVNano, West Virginia’s focal “Higher education fuels economic development nationwide, and this is precisely the type point in nanoscale science, of infusion that helps West Virginia grow and diversify,” Manchin said. engineering and education As a result of the RII award, researchers at the three institutions will bring together bionan - that was elevated to a statewide otechnology and molecular sciences to create hand-held devices – essentially a laboratory initiative through the 2006 RII on a chip – that can remotely identify potential environmental threats, pollutants and even award, has its first full-time, diseases. Innovations in these areas have the potential to create new marketable permanent director. Dr. Diandra technologies and devices – and the jobs to manufacture them. L. Leslie-Pelecky comes to WVNano from the Physics Additional institutions will have the competitive opportunity to collaborate on this ground - Department of the breaking research and position themselves for additional funding of their own. University of Texas at Dallas. West Virginia also was recently awarded a nearly $1.2 million award from the NSF through Prior to that position, the American Recovery and Reinvestment Act of 2009 to enhance cyberinfrastructure across she was at the the state’s higher education system over the next two years. As a result, WVU will advance its Nebraska Center for intra-campus cyberinfrastructure to current research standards and MU will work to enable Materials and inter-campus Internet2® access for the state’s predominantly undergraduate institutions, Nanoscience at community and technical colleges and the K-12 community. the University of Nebraska. A prolific writer and sought- Se after speaker, she is ptember 2010 the author of two books, including The Physics of NASCAR in 2008.

about the The Division of Science and Research, Higher Education Policy Commission, provides Division of Science strategic leadership for infrastructure advancement and development of competitive research opportunities in science, technology, engineering and mathematics disciplines. and Research The office directs the National Science Foundation’s Experimental Program to Stimulate Competitive Research (EPSCoR) in West Virginia, coordinates scientific research grants to academic institutions from federal and state agencies, and conducts outreach activities to broaden the public’s understanding of science and technology. More information – www.wvresearch.org

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n e u r o n 6

DIAGNOSING CANCER AT THE HEART OF NANOMATERIALS STUDIES AT WVU

Dr. Nick Wu, an associate professor in the Department of Mechanical & Aerospace Engineering at West Virginia University who was supported by the 2006 National Science Foundation Research Infrastructure Improvement award, is focusing on work that could change lives.

Wu recently received two National Institutes of Health (NIH) grants to develop nano-biotechnology to diagnose cancer and toxicity of nanoparticles. By incorporating nanomaterials with biomolecules, he is working to develop biosensors for detection of cancers, drugs and environmental toxins.

“Our goal is to develop new nano-biotechnology to improve our quality of life and also to protect humans against the side effects of new products,” said Wu, a participant in the WVNano initiative.

More information – www.cemr.wvu.edu Y E A R 50 S LEADERSHIP in HEALTH The Robert C. Byrd Health Sciences Center at WVU recently celebrated its 50th anniversary. WVU CENTER FOR NEUROSCIENCE AWARDED Over the past half-century, thousands of WVU Health $5.5 MILLION NIH GRANT Sciences graduates have cared for patients in every corner of The NIH recently awarded the WVU Center for Neurosciences a five-year, $5.5 million grant to support the state and across the country, new research technologies on the WVU Health Sciences campus. and West Virginians who need specialty care continue to rely The award will be used to further develop five core research facilities – genomics, advanced imaging, on WVU healthcare physicians. transgenic research, non-linear optical microscopy and tissues processing – used extensively by Research is a vital part of these neurosciences faculty and other researchers. efforts. According to a recent study, the state’s economy is The funding was awarded through the NIH National Center for Research Resources Institutional $2.2 billion larger because of Development Award program, designed to build Centers of Biomedical Research Excellence (COBRE). the presence of WVU’s health This is the third COBRE grant awarded to the Center for Neuroscience since 2000, marking a total sciences schools, clinics and investment of more than $23 million – which has spurred an additional $13.5 million in research hospitals. funding from other sources. More information – www.hsc.wvu.edu neuron 7

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neuron 8 t h e n e u r o n R WEST VIRGINIA’S SCIENCE, TECHNOLOGY AND RESEARCH COMMUNITIES 9

This year’s theme, “Sustainability: How Science, Technology and Research Can Sustain Our Future,” was underscored during panel discussions on energy, the environment, cyberinfrastructure and the economy. ptured first place in both categories of the symposium’s udent poster competition.

dical sciences Ph.D. student from Huntington, was recognized e Year.” William A. Kelly (below), an undergraduate biology was named “Undergraduate Researcher of the Year.”

-Kozup of West Virginia University in the graduate student niversity of Charleston in the undergraduate category.

Students enjoying STaR

ngs and presentations, are available at www.wvresearch.org. n e u r o n 10

RESEARCHERS AWARDED MORE THAN $1 MILLION FOR BREAST CANCER STUDIES

Two researchers at Marshall University have been awarded federal funds totaling more than $1 million to assess the effects of omega-3 fatty acids on breast cancer development.

The U.S. Department of Defense Breast Cancer Research Program awarded Dr. Elaine Hardman, associate professor in the Department of Biochemistry and Microbiology at the Joan C. Edwards School of Medicine, and Dr. Philippe Georgel, associate professor in the Department of Biological Sciences, competitive grants of $460,249 and $320,750, respectively. Hardman and Georgel received two of only 18 grants awarded nationwide through the program.

Over the next two years, Hardman and Georgel will use the funds to confirm earlier observations that consumption of canola oil, as a source of omega-3 fatty acid, in the maternal diet of mice could reduce risk for breast cancer in the offspring, and to identify the genetic changes associated with a maternal diet that contains omega-3 fatty acid. They hope to discover how canola oil is altering the expression of genes, with the goal of developing a panel of biomarkers to assess risk for breast cancer development in humans.

A third grant of $266,000 to Hardman from the National Institutes of Health will fund the final year of a related four-year study.

MARSHALL Marshall University has received $4.7 million in federal funding to support the new Center for Diagnostic Nanosystems at the university’s Robert C. Byrd Biotechnology Science Center. As a result, researchers at the RECEIVES center will focus on designing, developing and fabricating state-of-the-art diagnostic devices for cancer, $4.7 MILLION cardiovascular disorders, diabetes, dementia, infant care and air and water quality. “Work at the center will help scientists, physicians and the public better understand and integrate the FOR CENTER implications and applications of nanotechnologies, particularly as they unfold over the next decade,” said Dr. Eric Blough, the center’s director. “The center also will play an important role in stimulating FOR unprecedented interdisciplinary collaboration nationally among faculty members and students in DIAGNOSTIC the medical, biological, chemical, physical and life sciences, and engineering.” This funding, which was announced by U.S. Senator Jay Rockefeller, then-Senator Carte Goodwin NANOSYSTEMS and Congressman Nick Rahall, was added to Fiscal Year 2009 and 2010 Senate Appropriations bills at the request of the late Senator Robert C. Byrd. U.S. Department of Energy officials have formally released $2.9 million, with an additional $1.8 million expected soon.

More information – www.marshall.edu/murc/ n e u r o

WVU BIOMETRICS RESEARCHERS REDEFINING n “NIGHT VISION” 11

Researchers at West Virginia University are developing technology that gives night vision a whole new meaning – focusing on facial recognition and gait to identify a person in the dark.

The Night Biometrics Team at the Center for Identification Technology Research (CITeR) is comprised of Drs. Larry Hornak, Donald Adjeroh, Bojan Cukic, Jeremy Dawson, Xin Li, Arun Ross and Natalia Schmid, along with students in the Lane Department of Computer Science and Electrical Engineering.

“Automated facial recognition at a long distance and under both night and bright daylight environments is critical to fixing the identity of individuals who may pose a potential threat,” said Nathan Kalka, a doctoral student.

Other research is focusing on evaluating a person’s gait.

“We illuminate the person at wavelengths both undetectable by and safe to the human eye,” said fellow doctoral student Brian DeCann. “From the video of their movement, we evaluate the shape characteristics one displays while walking. Such a capability has potential for acquiring biometric traits from individuals at a distance when traditional biometrics such as face and iris are unavailable.”

Their work, funded under an Office of Naval Research award, was integrated into ONR’s Green Devil II initiative, a combination of several emerging ONR and various Marine Corps Programs of Record capabilities.

CITeR is the only National Science Foundation Industry/University Cooperative Research Center focused on the rapidly-growing areas of biometric identification and credibility assessment technology. WVU is the center’s founding and lead site.

More information – www.citer.wvu.edu d y t n

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