Viral structures and antibodies
www.abcam.com Herpesviridae
Envelope proteins Genomic DNA Tegument Capsid
Portal vertex
T=16
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HHV8 [LN35] M IHC-Fr, IHC-P 4103 Cytomegalovirus Glycoprotein B [2F12] M ELISA, IF, WB 6499 HSV1 + HSV2 gB [10B7] M ELISA, IF, WB 6506 EBV gp340/220 Envelope Protein [10B5] M ELISA, IF 6525 Varicella Zoster Virus [C90.2.8] M ICC/IF, IHC-P 49708 HHV6 [2Q1958] M ICC/IF, IHC-Fr, IHC-P 64536 Adenoviridae
Fiber Penton base Protease
Protein VI Hexon protein
Protein XI
Core proteins Terminal protein (V, VII and μ) T=25
VA E3 L1 IX L2 L3 L4 E1A E1B L5 TP PROTEIN 3’ ORI 5’ 5’ 3’ORI POL E2B E4 TP PROTEIN IVA2 E2A
Early Genes Late Genes
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Adenovirus Fiber monomer and trimer [4D2] M IF, WB 3233
Adenovirus Type 5 P ELISA, ICC/IF, WB 6982
Adenovirus hexon protein [8C4] M ELISA, Flow Cyt, ICC, ID, sELISA 8249
Adenovirus Type 5 hexon P Flow Cyt, ICC, ICC/IF, WB 24240
Adenovirus E1A [0.N.7] M IF, IHC-P, IP, WB 33183 Reoviridae
T=13 T=2 T=13 T=2 Orthoreovirus Rotavirus
Segment 1 Segment 8 c c VP1 Pol c NSP2 c Segment 5 c c Segment 2 NSp1 Segment 9 c c VP7(1) c VP2 c VP7 (2) Segment 6 Alternative initiation c Segment 3 VP6 c Segment 10 c c c VP3 NSP4 c
Segment 7 Segment 11 Segment 4 c NSp3 c c c VP4 c NSp5 c NSp6 Alternative initiation
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Rotavirus p42 [1-O-15] M ELISA, IP, WB 2598
Rotavirus (FITC) P ELISA, ICC/IF 31435
Rotavirus P ELISA, Neut 33639
Rotavirus P ELISA, IF 34886
Rotavirus P ELISA, ICC/IF, Neut 35417 Flaviviridae
E dimer M protein
Capsid protein
c
Genomic RNA
T=3 Capsid
Genomic polyprotein 5’ c 3’-OH
? CME NS1 NS2A NS2B NS3 NS4A NS4B NS5
Signal peptidase Golgi protease NS3 protease
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Dengue Virus NS1 glycoprotein [DN3] M ICC/IF, WB 41616
Hepatitis C Virus Core Antigen [C7-50] M ELISA, Flow Cyt, IF, IP, WB 2740
Hepatitis C Virus NS3 [8 G-2] M ELISA, ICC/IF, IHC-P, WB 65407
Hepatitis C Virus NS5a P ELISA, ICC/IF, WB 2594
Yellow Fever Virus [3576] M ELISA, IF, WB 22839 Orthomyxoviridae
Hemmaglutinin (HA)
Matrix (M1)
Neuraminidase (NA)
Polymerase complex (PA,PB1, PB2)
Nucleoprotein (NP)
M2 ion channel
Nuclear export protein (NEP)
Segment 1 Segment 7 5’ HO-3’ PB2 Segment 4 HO-3’ M1 5’ HO-3’ HA 5’ M2 Segment 2 HO-3’ PB1 5’ Segment 5 PB1-F2 Segment 8 HO-3’ NP 5’ Segment 3 HO-3’ NS1 5’ HO-3’ PA 5’ NEP Segment 6 HO-3’ NA 5’
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Influenza A Virus P Conjugation, IF, IHC-P 20841
Influenza A Virus Hemagglutinin H1 [B219M] M ELISA, WB 66189
Influenza A Virus Hemagglutinin H5 [15A6] M ELISA 59166
Influenza A Virus M2 Protein [14C2] M Flow Cyt, ICC, ICC/IF, IF, IP, WB 5416
Influenza A Virus Nucleoprotein [AA5H] M ICC, IF 20343 Retroviridae SIV nef SIV [BDI411] gp36 HIV2 [N3] tat HIV1 (HRP) p24 HIV1 [39/5.4A] p24 HIV1 Product VIRION Protease GENOME 5’ 5’ 5’ 5’ 5’ 5’ 5’ LTR c c c c c c c IMMATURE ACA MA CA MA GAG NC NC PR Ribosomal Cleavages by PR frameshift POL RT Reverse-transcriptase Nucleocapsid lnlt Applications Clonality gp120-gp41 IN Integrase Capsid Matrix Altenative initiation vif vif vpr M ELISA, IP, ELISA, WB M WB ELISA, 9071 M ICC/IF, ELISA, WB RipA, M WB P WB ICC, ELISA, P tat genomic RNA vpr vpu tat revrev vpu UTM SU ENV rev rev nef MATURE tat nef www.abcam.com/ab... LTR Data sheet Data 3’ 3’ 3’ 3’ 3’ 3’ 3’ 16129 20452 63957 20365
010-01/09-FF Paramyxoviridae
Matrix protein (M) Hemagglutinin-neuraminidase(HN)
Fusion protein (F) Phosphoprotein (P)
Nucleoprotein (N)
Polymerase (L)
(-) strand RNA genome C 3’ N P M F HN L 5’ leader V Trailer
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Measles nucleoprotein P ELISA, WB 23974
Mumps nucleoprotein [7B10] M I-ELISA, WB 9880
Newcastle Disease virus P ELISA 34402
Respiratory Syncytial Virus [2F7] M ELISA, ICC, IHC-Fr, WB 43812
Respiratory Syncytial Virus (HRP) P ELISA, IHC-P, Neut 20686
Hepadnaviridae
L glycoprotein S glycoprotein
Polymerase M glycoprotein
DNA3’
Core 5’RNA
T=4
preC C preS1 preS2 S X P
c
Pregenomic mRNA c LHBs mRNA c
MHBs & SHBs mRNA c X mRNA
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Hepatitis B Virus Core Antigen [10E11] M ELISA, ICC/IF, IHC-Fr, IHC-P, IP, WB 8639 Hepatitis B Virus E Antigen (HRP) [HBe3] M ELISA, sELISA 11443 Hepatitis B Virus pre S2 Antigen [S26] M ELISA, IHC-FoFr, IHC-Fr, IHC-P, IM, IP, WB 8635 Hepatitis B Virus Surface Antigen P Conjugation, ELISA 20522 Hepatitis B Virus X antigen [3F6-G10] M ELISA, IHC-Fr, IHC-P, WB 235 Polyomaviridae
VP1 VP2 VP3
Histone
Genomic DNA
T=7d
SELP AGNO
ST-Ag
VP2 Polyomavirus SV40 5.2Kb VP3
VP4
g LT-A VP1
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Human Polyoma virus JCV capsid protein VP1 M I-ELISA, WB 34756
Polyoma virus, Medium T antigen M ICC/IF, IP 15085
SV40 T-antigen [PAb416] M ICC, ICC/IF, IP, WB 16879
SV40 VP1 P ICC/IF, IP, WB 53977
SV40 VP2 + VP3 P WB 53983 Filoviridae
VIRION Minor Nucleoprotein (VP30) Glycoprotein (GP)
Nucleoprotein (N)
Polymerase complex protein (VP35) Genomic RNA VP24
Matrix (VP40) Polymerase (L)
(-) strand RNA genome RNA editing
3’-OH NP vp35 vp40 GP vp30 vp24 L 5’ Leader sGP Trailer
c
c L mRNA Vp24 mRNA c Vp30 mRNA c GP mRNA c Vp35 mRNA c Sequential transcription Vp40 mRNA c N mRNA
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Ebola virus [FE18] M ELISA, WB 1918
Ebola virus [FE37] M ELISA, WB 1926
Marburg Virus [FM11] M ELISA, WB 2055
Marburg Virus [FM213] M ELISA, WB 2059
Marburg Virus [FM214] M ELISA, I-ELISA, WB 10003 Antibody licensing and Abreviews
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