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Catalog Number:ATP123 Anti PON3 polyclonal antibody

Product overview product name Anti PON3 polyclonal antibody catalog No. ATP123

Category Primary antibody

Host Rabbit

Species specificity Human,other species was not test

Tested applications ICC:1:50~200,IHC:1:50~100

Clonality Polyclonal

Conjugation Unconjugated

Immunogen Recombinant of human PON3(Leu22-Leu354).

Alternative Names Serum /lactonase 3,PON3

Uniprot ID Q15166

Product performance

Form Liquid

Buffer PBS,pH7.4,containing 0.05% proclin300,50% glycerol.

Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4°C

for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.

Concentration 0.79mg/ml

Isotype IgG

MW 40kDa

Purity Antigen affinity purification

Dilution range

ICC,IHC

Product experiment picture

Web:www.atagenix.com E-mail: [email protected] Tel: 027-87433958 ATAGENIX LABORATORIES

Catalog Number:ATP123 Anti PON3 polyclonal antibody

Reference

PMID: 15772423;PMID: 16335952;PMID: 32092131

Product background

Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon.

Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The which encode PON1-3 are physically linked and map to human

7q21.3.

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