Product Datasheet

FAM107A Conjugated Antibody

Catalog No: #C36461

Package Size: #C36461-AF350 100ul #C36461-AF405 100ul #C36461-AF488 100ul Orders: [email protected] Support: [email protected] #C36461-AF555 100ul #C36461-AF594 100ul #C36461-AF647 100ul

#C36461-AF680 100ul #C36461-AF750 100ul #C36461-Biotin 100ul

Description

Product Name FAM107A Conjugated Antibody

Host Species Rabbit

Clonality Polyclonal

Species Reactivity Hu

Specificity The antibody detects endogenous levels of total FAM107A protein.

Immunogen Description Full length fusion protein

Conjugates Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

Other Names DRR1; TU3A

Accession No. Swiss-Prot#:O95990NCBI Gene ID:11170NCBI Protein#:BC010561

Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

Storage Store at 4°C in dark for 6 months

Application Details

Suggested Dilution:

AF350 conjugated: most applications: 1: 50 - 1: 250

AF405 conjugated: most applications: 1: 50 - 1: 250

AF488 conjugated: most applications: 1: 50 - 1: 250

AF555 conjugated: most applications: 1: 50 - 1: 250

AF594 conjugated: most applications: 1: 50 - 1: 250

AF647 conjugated: most applications: 1: 50 - 1: 250

AF680 conjugated: most applications: 1: 50 - 1: 250

AF750 conjugated: most applications: 1: 50 - 1: 250

Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Background

FAM107B is a 131 amino acid protein that is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Note: This product is for in vitro research use only and is not intended for use in humans or animals.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2