T611234 Anti-RNF7 Rabbit pAb
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Product Information
Description RNF7 rabbit polyclonal Protein full name RING-box protein 2
Synonyms Rbx2, RING finger protein 7, Sensitive to apoptosis gene protein, Rnf7, Rbx2, Sag Immunogen KLH conjugated Synthetic peptide corresponding to Mouse RNF7 Isotype IgG Purity Affinity purification Subcellular Cytoplasm, Nucleus location
Uniprot ID Q9UBF6, Q9WTZ1
Applications
Applications IHC IF
Species Human, Mouse, Rat Human, Mouse, Rat
Dilution 1: 500-1: 1000 1: 500-1: 1000
Positive tissue ovary cancer, colon cancer, testis, spinal cord, kidney, lung, fetal mouse, heart, uterus, lung, spleen kidney
Background
The RNF7 is probable a component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
Images
Immunohistochemistry analysis of paraffin- embedded human ovary cancer using RNF7 (T611234M) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin- embedded human colon cancer using RNF7 (T611234M) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin- embedded mouse testis using RNF7 (T611234M) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin- embedded mouse spinal cord using RNF7 (T611234M) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin- embedded mouse kidney using RNF7 (T611234M) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin- embedded rat lung using RNF7 (T611234M) at dilution of 1: 1000
Immunohistochemistry analysis of paraffin- embedded rat spleen using RNF7 (T611234M) at dilution of 1: 1000
Immunofluorescent analy sis of paraformaldehyde- fixed fetal mouse tumor using RNF7 (T611234M) at dilution of 1: 2000
Immunofluorescent analy sis of paraformaldehyde- fixed mouse heart using RNF7 (T611234M) at dilution of 1: 4000
Immunofluorescent analy sis of paraformaldehyde- fixed mouse uterus using RNF7 (T611234M) at dilution of 1: 2000
Immunofluorescent analy sis of paraformaldehyde- fixed rat lung using RNF7 (T611234M) at dilution of 1: 2000
Immunofluorescent analy sis of paraformaldehyde- fixed rat kidney using RNF7 (T611234M) at dilution of 1: 2000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
NOTE: This product is intended for research only.