Anti-ABCC10 monoclonal antibody, clone N8J-4 (CABT-26241RH) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rat monoclonal antibody to Human ABCC10.

Antigen Description The encoded by this is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC transport various molecules across extra- and intra-cellular membranes. ABC are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen Fusion protein containing internal amino acids 194 - 272 of Human ABCC10.

Isotype IgG

Source/Host Rat

Species Reactivity Human

Clone N8J-4

Purification Tissue culture supernatant

Conjugate Unconjugated

Applications FC, ICC, IHC-Fr, WB

Sequence Similarities Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.Contains 2 ABC transmembrane type-1 domains.Contains 2 ABC transporter domains.

Format Liquid

Concentration 0.250 mg/ml

Size 500 μl

Buffer Preservative: 0.1% Sodium AzideConstituents: 0.7% BSA, Serum free tissue culture supernatant

Preservative 0.1% Sodium Azide

Storage Store at +4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved GENE INFORMATION

Gene Name ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 [ Homo sapiens ]

Official Symbol ABCC10

Synonyms ABCC10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; multidrug resistance- associated protein 7; ABCC10; ATP binding cassette, sub family C (CFTR/MRP), member 10; ATP binding cassette, subfamily C, member 10; ATP-binding cassette sub-family C member 10; EST182763; mFLJ00002; MRP7; MRP7_HUMAN; Multidrug resistance associated protein 7; Multidrug resistance-associated protein 7; SIMRP7; OTTHUMP00000016438; OTTHUMP00000016441; ATP-binding cassette sub-family C member 10; MRP7; SIMRP7; EST182763;

Entrez Gene ID 89845

Protein Refseq NP_001185863

UniProt ID A0A024RD21

Pathway ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC- family proteins mediated transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem;

Function ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; nucleotide binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved