Gujarat : An Enduring Strong Economy

. Population : Over 50 million (5.0% of )

. Geographical area : 1,96,000 sq. km (6.2% of India)

. Gross State Domestic Product (GSDP) : US$ 45.3 billion

. Per Capita Income : US$ 915 at current prices

. Urbanisation : 37.4%

. High industrial growth : Gujarat has demonstrated a Composition of GSDP as per economic activity (2006-07) high industrial growth rate of 12.5% from 2002 - 2007

. Industrialisation : Gujarat is home to over 800 large 18.2%

industries and 3,20,000 micro, small and medium Primary Sector 44.0%

enterprises Secondary Sector 37.8% Tertiary Sector

Source: Socio Economic Review 2007-08

2 Gujarat : A Thriving Industrial State

Contribution to National Economy Presence across industry sectors

Stock market capitalization 30.0%

Coastline 22.0% Petroleum products 31.2 %

Exports 21% Chemical & Pharma 22.9 % Engineering Industries 12.6 % 17.0% Fixed capital investment Food & Beverages 9.7 % Textiles & Apparels Value of output 15.6% 6.5 % Mineral based industries 2.9 % Net value added 14.0% by manufacture Metallurgical Industries 7.5 %

No. of Factories 10.0% Others 6.7 %

Employees 9.5% Significant share in key sectors & products

Soda ash production 98.0% . World’s largest producer of castor and cumin Salt processing 85.0%

Diamond processing 80.0% . World’s largest gas based single location sponge iron plant

Plastic industry 65.0% . World’s largest producer of processed diamonds

Petrochemicals 58.0% . World’s 3rd largest producer of denim Chemicals 50.0% . Asia's largest grass root petroleum refinery at Jamnagar Groundnut 42.3% . India's largest producer of cotton Pharmaceuticals 42%

Cotton . 35.0% India's first LNG chemical port terminal at Hazira

Fabrics 30.0%

Source: Socio Economic Review 2007-08

3 Gujarat: Robust Infrastructure

Power Dependable power supply – key to industrial development

. Present power generation capacity is 9,628 MW; plans afoot to raise it to 25,000 MW by 2012 . Per capita power consumption is 1,354 units against the national average of 665 units . Rich availability of natural gas (34 MMCD) and lignite (1,072 MMT) . 24-hour 3-phase uninterrupted power supply

Gujarat is the only State to carry out interlinking of rivers Water

. An extensive water grid network of 75,000 km for irrigation and drinking . It will cover 75% population of the state by 2010

Gas Transformation of economy through natural gas

. Gujarat State Petronet Limited (GSPL) supplies piped gas to 13 districts, 5 more districts will be added . Total length of Integrated Gas Grid will be 2,200 km, of which 1,453 km is complete and the rest is under construction

4 Gujarat: Robust Infrastructure

Rail and Road Surfaced road length – one of the highest in Gujarat

. State-of-the-art road infrastructure: India’s first National Expressway between Ahmedabad to Vadodara operational . Total road length is 74,018 km - 95% surfaced road . Rail length in Gujarat of 5188 km (8.25% of India)

Gujarat Ports opening the gateway to prosperity Ports . 42 ports along 1,600 km coastline, major port at Kandla other important ports at Mundra and Pipavav. . Landmark projects such as LNG port terminal at Hazira developed by Shell India Limited, Green field port at Mundra developed by Gujarat Adani Port Limited, LNG terminal at Dahej developed by Petronet LNG Ltd. and Pipapav port developed by Gujarat Pipapav Port Ltd

Airports Airport connectivity – a cutting edge for business

. 13 airports - Vadodara, Surat, Jamnagar, Rajkot, Bhavnagar, Porbandar, Bhuj, Keshod, Mandvi, Mundra, Kandla, Palanpur, Deesa and Ahmedabad (International Airport)

5 Global Biotechnology: The Sunrise Industry

The Global Biotechnology market generated total revenues of US$84.78 billion in 2007

. The collective revenues of public traded biotech companies grew 8% by Table 1: Global biotechnology industry snapshot

across the globe in 2007, generating total revenues of US$84.78 billion for the Geography Revenue R&D % share % share first time ever U.S. 76.87 81.35 Europe 15.26 14.35 . The research and development costs were up by 7%, clearly demonstrating Canada 3.27 2.8 that a number of new products are expected to come to the market Asia Pacific 4.6 1.5

. Globally, there are a total of 798 public biotech companies and 4,414 private

and public companies Fig 1: Geographic concentration of Biotech players 18%

36% . The biotech industry employs directly about 200,000 people (public 9%

companies only) with highest share of 66% employed by US U.S. Europe Canada Asia-Pacific 37% Source: Ernst & Young Biotechnology report –Beyond Borders 2008

6 Indian Biotechnology: Gaining Momentum

India is one of the five emerging biotech leaders in the Asia-pacific region

. India's biotechnology industry is now a US$3 billion sector, World’s largest producer of Vaccines registered a 30 % growth in 2007-08 over the previous year . Revenues of US$2.08 bn in 2006-07 with a growth of 30.98% World’s largest cultivator of Bt Cotton . Exports of US$1.20 bn with 58% share in total revenues in fiscal

2006-07 1st in terms of growth in transgenic crops . Biopharma generated 71% of total industry revenues in 2006 . Investments of US$580 million in 2006-07, up by 38% 3rd highest with biotech companies in Asia Pacific

Fig 2: Sector - wise Revenue Break up – 2006-07 Table2: Regional distribution of Biotech revenues Map 1: Biotech clusters in India

Region No. of Revenues %

4%2% Companies (INR crore) share 11% Delhi-Gurgaon-Noida Biopharma North 43 1025 12% Bioservices Ahmedabad-Vadodara 13% Bioagri Aurangabad Bioindustrial South 152 3416 40% Bioinformatics Mumbai-Pune 70% Hyderabad West 135 4100 48% Chennai Source: GSBTM Bangalore Total 330 8541 100%

Source: Biospectrum 2006-07 Source: DBT India’s first integrated Biotechnology Incubation Centre (BTIC) to start operations in September 2008

Source: IBEF, Biospectrum,, Ernst & Young Biotechnology report – Beyond Borders 2007.

7 Biotechnology in India: Education Mechanism

. 40 National Research Laboratories employing 15,000 scientists . 300 college-level educational and training institutes . Degrees and diplomas offered in biotechnology, bioinformatics, and biological sciences enrolling 300,000 students annually . 100 medical colleges qualifying 17,000 medical practitioners per year . 100,000 post graduates and 1500 PhDs qualifying in biosciences and engineering each year

Courses offered Institutes Biotechnology Institutions

M.Sc. General Biotechnology 30  Centre for DNA Fingerprinting and Diagnostics M.Sc. Agricultural Biotechnology 7  Institute of Bioresources and Sustainable Master in Medical Biotechnology 1 Development M.Sc. Marine Biotechnology 2  Institute of Life Sciences M.Sc. Neurosciences 3  National Institute of Immunology

M.Sc. Industrial Biotechnology 1  National Centre for Plant Genome Research

M.Tech Biochemical engineering and biotechnology 6  National Brain Research Centre  National Centre for Cell Sciences M.Tech Pharmaceutical Biotechnology 1  Indian Vaccines Corporation Limited Post MD/MS certificate course in Medical Biotechnology 2  Bharat Immunologicals and Biologicals Corporation PG Diploma course in Genetic engineering and Bioprocess development 1 Ltd. PG Diploma course in Molecular and Biochemical Technology 1  Indian Council of Medical Research

Source: Department of Biotechnology

8 Evolution of Biotechnology in India

1980 1982 1983 1986 Formulation of Policy for Setting up of The National Long-term plan in NBTB was replaced by development of Biotechnology Board Biotechnology for India actual government body biotechnology with (NBTB), an official apex issued by National called Department of implementation of India’s body dedicated to Biotechnology Board Biotechnology (DBT) sixth five year plan Biotechnology

Major Milestones in Indian Biotechnology Industry

First decade Second decade Third decade

1978 : Country’s first Biotech company 1991 : National Centre for Biological 2000 : Country’s first bioinformatics BIOCON was established Sciences pursue R&D in molecular biology company Strand genomics formed 1981 : Centre for Cellular and Molecular 2000 : GENOMED, country’s 1st Joint venture 1994 : Syngene International, country’s 1st Biology was set up in Hyderabad between Institute (CBT) and Industry CRC offer R& D services 1984 : Institute for Microbial Technology (Nicholas Piramal) to pursue was set up in Chandigarh 1997 : Shantha Biotech launches India’s pharmaco-genomics 1986 : Department of Biotechnology was first recombinant product, Hep B vaccine 2001 : Reliance sets up Reliance Life established by 1998 : Monsanto research establishes R&D Sciences to pursue stem cell research 1987 : National Institute of Immunology was 2001 : Drug authority implements GCP set up by DBT in New Delhi centre for plant genomics guidelines for clinical trials 1989 : Bangalore GENEI starts its 1998 : DBT approves Mahyco-Monsanto to 2002 : GEAC approves Bt cotton for operations conduct Bt cotton trials commercial planting

Source: Department of Biotechnology, Association of Biotechnology led Enterprises

9 Evolution of Biotechnology in India

Classical biotech companies to modern biotechnology

Company Traditional Business New Business

Biocon Industrial enzymes Insulin, Monoclonal antibodies, Biologicals Serum Institute of India Conventional vaccines rDNA vaccines Bharath Serums and Conventional vaccines rDNA vaccines and Monoclonal antibodies Vaccines rDNA vaccines, Monoclonal antibodies, Panacea Biotech Conventional vaccines Peptides

Indian Immunologicals Conventional vaccines rDNA vaccines Biological E Conventional vaccines rDNA vaccines

Source: Indian Biotechnology Report, Business world

10 Gujarat: An Emerging Biotechnology Hub

For the year 2007, Gujarat State has been given Bio state of the year award

. The landscape of Gujarat biotech industry, consist of more Map 2: Biotechnology in Gujarat – Location Analysis than 50 Biotechnology companies and 66 support Gandhinagar organizations . The thrust areas of Gujarat biotech industry include Patan healthcare, pharmaceuticals, agriculture biotechnology, Mehsana Sabarkantha industrial enzymes, bioinformatics, contract research, marine and environmental biotechnology . The present annual turnover in biotechnology in Gujarat Surendranagar Rajkot has been around US$150 – 175 million Anand . Some of the prominent domestic biotech companies Amreli Bharuch include Zydus Cadila, Concord biotech, Cadila Bhavnagar Pharmaceuticals, Maps India and Intas. Junagadh Surat Players like Sterling Biotech, Zytex Biotech, Bayer

. Cropscience and Quintiles have started their operations in Ahmedabad Biotech Cluster Valsad Gujarat. New start ups include Aumgene Biotech, Augene

Biotech, Enzymes Ltd., etc. Academic institution Vadodara Biotech Cluster Manufacturing organisation R & D organisation Source: Gujarat State Biotechnology Mission, An analytical report on Biotechnology sector in Gujarat, Biospectrum

11 Biotechnology: The Next Big Frontier

Sector Break-up Stakeholders

Academic Others 8% institutions 20% Environment 6%

Industrial 6%

R & D institutions 11% Corporates 67% NGOs Agriculture 20% Healthcare 60% 2%

Gujarat biotech value proposition

Strong base of pharma Rich Rich reservoir of medicinal and Emerging Education and and bioresource marine resources Research base healthcare sector

5% 4 agriculture Marine, 926 species 462 species 783 species pharma sector universities biodiversity Bioinformatics, of medicinal of marine of marine meeting 45% of and 29 of the Agriculture and plants flora fauna nation’s needs biotech country colleges other

Source: iNDEXTb, Gujarat State Biotechnology Mission

12 Investments in Biotechnology - Gujarat

Fig 5: Investments proposed during VGGIS . Global Investor's Summit 2007 witnessed 1800 1541 1600 of US$367 million with a total of 19 MoUs between the state 1400 biotech players and industrialists from abroad and outside 1200 1000 Gujarat 800 600 348 . Some of the players are MJ Bio-Pharma, Oxygen Healthcare and 400

MABS International have shown interest in invest in Gujarat Investments (INR crore) 200 0 2005 2007 Years Major alliances with foreign Investments planned by major players in Gujarat State partners  US-based Stemcyte Corporation has committed to invest in Ahmedabad Altana and Zydus Biogen with an investment of US$ 24 million

Reliance  Hyderabad based NUSUN has finalised its plans to invest in the State GenMedix Life sciences  Vaishnavi Biotech (subsidiary of Hyderabad-based Pratistha group) is Intas Virionics investing in biopesticide project at Bhavnagar district Biopharma Corporation  US-based AMNEAL Pharma is investing around US$12 million for its pre- Parexel and Synchron Innovance clinical facilities at Ahmedabad

 Sterling Biotech has made investments at Vadodara for gelatin production Alembic UCB

Source: Industries Commissionerate, IBEF Biotech report, News articles, GSBTM

13 Value Chain Analysis

Integration and Marketing Basic Drug Transportation product Manufacturing and Services research discovery logistics development sales

Business Areas

. Agriculture . Clinical research biotechnology . Industrial testing . Microbiology . Biochemistry . R&D Sea water, marine Services

. Genetic engineering Marketing algae

. Plant tissue culture Manufacturing . Environmental . Plant and animal . Agriculture . sciences Research Medicinal and Education aromatic plants . Pharma technology Presence across value chain Areas . Blood collection . Industrial and testing biotechnology . Healthcare Marine Industrial Agriculture

Crop Bioinformatics Preventive Biopharma Seeds Pharmaceutical Diagnostics protection medicines therapeutics

Growth Sector areas Nutraceuticals Vaccines stimulator Phyto pharmaceuticals

Source: A Compendium of Biotechnology Organizations in Gujarat, E&Y analysis

14 Gujarat: Industrial Strengths and Opportunities

Agriculture Biotechnology Major players Opportunities  Gujarat has sizeable agrarian economy with major . Bayer Cropscience Ltd. . Tissue culture percentage of land under cultivation in central Gujarat . . Excel Cropcare Ltd. Biofertiliser and Biopesticides  Stakeholders in Agri-biotech segment represent industry, . Biofuel . Gujarat life sciences . Transgenic crops and GM . NGOs, Government PSUs and laboratories and Centres of Gujarat State Fertiliser & crops Chemicals Ltd. Excellence . Organic food

Major players Pharmaceutical and healthcare biotechnology Opportunities

. Zydus Cadila  Gujarat’s pharmaceutical sector accounts for around 45% of . Biopharmaceuticals . Torrent Pharmaceuticals the total pharmaceutical output in the country. . Vaccines . Sun Pharma . Diagnostics . Concord . Monoclonal antibodies  The State has around 3267 registered units with total . Cadila Pharma . Stem cell . investments of US$1.6 billion Intas . Animal healthcarea

Major players Industrial biotechnology Opportunities  Gujarat being home to the chemical industry, has developed . Maps (India) Ltd. . Industrial enzymes . Anil Biochem Ltd. strength s in the industrial enzymes segment and has been . Yeast-based- products . Americos Industries Inc. able to leverage its manufacturing strength in industrial . Specialty chemicals . Zytex Biotech biotechnology . Organic amino acid

Source: Gujarat State Biotechnology Mission, An Analytical Repor t on the Biotechnology Sector in Gujarat

15 Gujarat: Industrial Strengths and Opportunities

Environmental biotechnology Opportunities  Gujarat has varied climate with diverse ecosystem

. Biofuel  Various organisations playing key role in the areas of environment . Bioremediation services conservation include centre for Environment Education, The . Effluent treatment / solid waste management Science Ashram, Gujarat Science Foundation, SRISTI, VIKSAT . Biofertiliser

Bioinformatics  There are eight universities in Gujarat offering graduate and post Opportunities graduate courses in Bioinformatics . Drug discovery and development . Bioinformatics software development  Some of the government and industrial organisations involved in . Proteomics and Molecular modeling research include IIAR, GCRI, B.V.Patel PERD centre, Zydus . Structural and functional genomics Research Centre, Dhirubhai Amb-IICT among othersani . Analysis of online biological databases

Marine biotechnology  Gujarat has 1600 km long coastline, rich in marine resources Opportunities

.  Marine biotechnology has found its application in an array of Bioprospecting . ISO or GMP certified Hatcheries industries like pharmaceuticals / healthcare, consumer products, . Cultivation of Seaweeds for Biomolecules and Biofuel industrial products and processes, agricultural, environmental . Diagnostics for Aquaculture remediation and pollution control Source: Gujarat State Biotechnology Mission, Bioinformatics Compendium, An Analytical Report on the Biotechnology Sector in Gujarat

16 Gujarat Location Analysis: Planned Infrastructure

Proposed biotech zones And biotech parks

Location Biotech zones (Proposed)

Ahmedabad-Surendranagar Biopharma Zone

Jamnagar-Dwarka-Porbandar Marine Biotechnology Zone

Food and food processing Vadodara-Anand-Nadiad Location Biotech parks (Proposed) for Animal Biotechnology Vadodara Industrial Park Vapi-Surat-Bharuch- Biochemical engineering for Ankleshwar Industrial Biotechnology Anand Food Biotechnology Park

Junagadh-Bhavnagar Jamnagar/Bhavnagar Marine Biotechnology Park Banaskantha-Mehsana Agri Biotechnology

Gandhinagar/Mehsana Agri Biotechnology Park

17 Available Infrastructure - Savli Biotech SEZ

. Savli Biotech is earmarked as a Special Economic Zone for Biopharmaceutical companies

. The SEZ has a location advantage because of its proximity to Vadodara. It is also well- connected to Ahmedabad through expressway, and to Mumbai through NH-8 connected to Ahmedabad through expressway, and to Mumbai through Vadodara . Proximity to Vadodara provides access to high quality scientific talent, research and development infrastructure, Ahmedabad - Vadodara commercial corridor and excellent social and urban infrastructure

Would be developed as a Public-Private Venture over 700 acres in three phases

Industry arcade Innovation arcade

 Plots with water supply, telecommunications, uninterrupted  Modular wet labs: To include plug and play modular labs power supply, acid proof drainage system and gas pipelines targeting entrepreneur driven small and mid sized research  Common Utilities: Gas chambers, dedicated power feeders, organisations effluent neutralisation and disposal plants and sewage treatment plants  GAURI (research and training institute): To train readily  Animal house: To conduct toxicology studies employable workforce for the biotechnology industry  Service block: To house logistic companies, venture capital firms, travel desks, etc.  Loaded wet labs: To be furnished by basic equipments required  Amenity and Administrative block: To house business by biotech research enterprises facilitation centre, auditorium, audio visual room and a food  Common Equipment Library court

18 Gujarat : Other SEZ Opportunities

Ahmedabad

Area: 48.83 hectares Bharuch

PHARMEZ (Zydus Cadila)

Area: 200 hectares Area: 130 hectares

PHAEZ (Cadila Pharma) J B Chemicals SEZ

Area: 139 hectares

Dishman Pharma SEZ

19 Gujarat Investment Opportunities

R & D / Manufacturing

Marine Agriculture Pharmaceutical / Healthcare Industrial

• Aquaculture • Ethanol manufacturing unit • Human vaccines manufacturing • Biopolymer unit • Enzymes from marine • Manufacturing of biofertilisers manufacturing resources • Manufacturing of human • Manufacturing of biopesticides • Manufacturing of diagnostic kits • Marine resources for • Manufacturing of plant diagnostic kits industrial biocatalysts new molecules • Manufacturing unit for monoclonal • Biodiesel plant-based on Jatropha antibodies • GM crops with seeds • Veterinary vaccines manufacturing • Tissue culture unit

• Bionutraceuticalsa • Stem cell

Infrastructure Bioservices

• Marine biotechnology park • Contract research (pre-clinical and

• Agricultural biotechnology Park Clinical)

• Biotechnology training centres • Bioremediation • Quality certification / validation facilities

20 Gujarat - Leading Industry Players

Ahmedabad Vadodara

Rajkot

Ankleshwar

Surat

21 Gujarat Leading Industry Players: Existing Business Platform

Company Key activities Business area Key products

. Concord Biotech Ltd. is an Ahmedabad-based . A pure play biotech . Enzymes biotechnology firm manufacturing enzymes and company with specialisation . Statins biopharmaceuticals in : . Immunosuppressant . It is the second company in the world to produce  Healthcare Tacrolimus - Immunosuppressant  Industrial

. Zydus Cadila, headquartered at Ahmedabad has . A diversified pharmaceutical . Vaccines presence in formulations, APIs, diagnostic, herbal company with its focus in . Diagnostic kits and animal healthcare  Healthcare . Nutritional supplements . Its Biotechnology-related research includes . Anti diabetes drugs biogeneric therapeutic proteins, anti bodies, . Women healthcare drugs vaccines, diagnostic kits and search for novel . Anti cancer drugs targets

. Map’s is India’s largest producer and exported of . Pure play biotech company . Industrial enzymes industrial enzymes  Industrial biotechnology . Biochemicals . The company’s portfolio of enzymes include  Environmental amylases, proteases, cellulases, xylanase, biotechnology glucomylase, pectinase and catalase

. The company also produces a range of biochemicals

22 Gujarat Leading Industry Players: Existing Business Platform

Company Key activities Business area Key products

. Intas Pharmaceuticals has a biotechnology . A diversified pharmaceutical . Recombinant proteins subsidiary ‘Indus Biotherapeutics’ company with specialisation (rHu G-CSF) . It focuses on recombinant protein based products in : mainly for oncology and nephrology segments  Healthcare . The manufacturing technology used by the company is cell culture and fermentation based

. Formed in 2002, Bayer Crop Science has emerged . A diversified pharmaceutical . Biopesticides as one of the world’s leading enterprise in crop company with specialization . Growth stimulators protection, seeds, biotechnology and non in : agricultural pest control  Agriculture

. Gujarat Life Sciences is promoted as a joint venture . Company with specialization . Biofertilsers company with Gujarat Agriculture University and in : . Biopesticides Government of Gujarat  Agriculture . Effluent treatment/solid . The company’s business areas include novel  Environment waste biocomposting biotech formulations in agricultural biotechnology, . Organic farming effluent treatment, domestic marketing and export . Horticulture consultancy of biologicals, custom development of new processes/products in technology transfer and biotechnology

23 Gujarat Leading Industry Players: Existing Business Platform

Company Key activities Business area Key products

. Anil Biochem Ltd. is the only company in India that . Diversified chemical . Calcium gluconate manufactures calcium gluconate by fermentation company with focus in: . Sodium gluconate process  Industrial biotechnology . Alpha Amylase Enzyme . The company has state-of-the-art manufacturing  Biochemicals . Protease Enzyme facility, a separate submerged enzyme plant, a tray . Amyloglucosidase plant and well equipped R & D facility Enzyme

. Quintiles is the first global Contract Research . Services company . Drug development Organisation (CRO) to set up their operations in . Study protocol India development . It has experience for studies in oncology, . Phase II through IV trials psychiatry, neurology, anti infective, . Data management gastroenterology, ophthalmology, endocrinology . Biostatistical analysis and cardiology

. Span Diagnostics Ltd. is a pioneer and trend setter . Pure Play . Serology of high quality products for pathology and clinical  Primary Healthcare . Polyclonal and laboratories in the Indian diagnostics industry (Diagnostics) monoclonal antibodies . Clinical chemistry reagent . It is a globally acknowledged and fastest growing . Hematology infectious diagnostic company with a successful track record of over three decades disease . Recombinant antigens based tests

24 Hester Pharmaceuticals: A Success Story

. Hester Pharmaceuticals is a leading biotech company in the field of Sales (INR lacs)

veterinary biologicals located in Ahmedabad 2500 2182.79 2013.70 2000 1623.91 1500

. It is a GMP -based company manufacturing more than 39 types of 1000 768.13 441.28 poultry vaccines since 1997 500

0 2002-03 2003-04 2004-05 2005-06 2006-07 . Its product range include live and killed veterinary vaccines, Source: Company annual report 2006-07 diagnostic kits, and seromonitoring services Hester Pharmaceuticals represent international producers . Ghen Corporation, Japan . It reached 100% capacity utilisation during financial year 2006-07 . Marine Biological Labs, USA producing 1260.28 million doses of poultry vaccines . Biogalgalted Labs, Israel . Kermin Europa, Belgium . Hester has an exclusive marketing tie-up with Merial Inc., World’s . Sinsui Inc., Tokyo largest Animal Health Company and biggest producer of poultry vaccines for marketing their range of poultry vaccines in India “We have the largest number of vaccine licenses registered by any Indian Company” - CEO and MD, Rajiv Gandhi

. The company is in the process of setting up dedicated R&D centre “Hester Pharmaceuticals currently enjoys a tenth of the market. We want to capture a fifth of the market next year” for the development of newer vaccines - CEO and MD, Rajiv Gandhi

25 Novartis-Chiron Synergies: A Success story

Novartis – Swiss-based company Chiron – US-based company Active in the development, production and Active in the development, production and marketing

distribution of medical products, including Blood testing products: equipments and reagents prescription drugs, OTC drugs and Biopharmaceuticals: Oncology, infectious and pulmonary diseases animal health products Human vaccines: Influenza, meningococcal, pediatric and travel

. Novartis acquired California-based company, Chiron, in April 2006, creating Novartis Vaccines and Diagnostics

. Based in Siena, Novartis Vaccines and Diagnostics is a fully integrated biotech company doing research, manufacturing and marketing of vaccines

. It is one of world’s five largest companies and the world’s second largest manufacturer of flu vaccines

. Through Chiron’s acquisition, Novartis has created a new strategic platform focused on human vaccines and also access to the markets of blood testing equipments and biopharmaceuticals

. The company’s portfolio of products include vaccines for influenza, meningitis, rabies, tick borne encephalitis, haemophilus influenza B (Hib), polio, diphtheria, tetanus and pertussis (whooping cough)

26 Educational Infrastructure: The Key driver

. Gujarat has 14 universities and more than half a dozen research institutes imparting post graduate and under graduate courses in biotechnology and related allied sciences

. About 20 institutes offer UG courses, five offer PG courses, six offer doctoral courses and seven offer diploma courses

. The state produces around 5,000 manpower trained in biotechnology which includes Ph.D.s, post graduates, PG diploma, undergraduates and other diploma courses

Under graduate manpower in biotech and allied subjects in Gujarat Post graduate manpower in biotech and allied subjects in Gujarat

116 1660 155 312

822 54

239 290 80 288 120 280 100 29040 101 50 Agriculture Biochemistry Biotechnology Agriculture Biochemistry Biotechnology Microbiotechnology Bio-informatics Bio medical instrumentation Microbiotechnology Bio-informatics Environmental Science Environmental Science Medical technology Others Medical Technology Others

Source: Gujarat State Biotechnology Mission

27 Gujarat Biotechnology Educational Infrastructure: The Key driver

GSBTM education initiatives

. Gujarat Integrated Biotechnology Network (GBioN) linking universities and colleges

. Molecular Biology Bioinformatics teachers training program (MBTeach) for skill development in teachers

. Gujarat Biotechnology Crash residential program (GBCRP) for skill development in students

. GSBTM to start training program in Clinical trials and genetic diagnostics

Source: Gujarat State Biotechnology Mission

28 Gujarat Biotechnology: Academic Infrastructure

Existing Ecosystem of Education and Research Institutes

. Gujarat Cancer Research Institute . Directorate of Forensic Science . B.V. Patel PERD centre . Zydus Research Centre . North Gujarat University . Department of Biotech, Gujarat University . National Research centre for Medicinal and . Nirma Institute of Pharmacy Aromatic Plants . National Dairy Development Board . Gujarat State Fertilisers Corporation . Sun Pharma research centre . National Research Centre for Groundnut . MS University of Vadodara . . Central Salt and Marine Chemicals Research Institute Anand Agriculture University . Department of Life science, Bhavnagar University . Junagadh Agriculture University . Navsari Agriculture University . Department of Bioscience, Saurashtra University

29 Gujarat Biotechnology and Research Institutes

. Anand Agriculture University, Anand . CP college of Agriculture, Sardar Krushinagar . Junagadh Agricultural University, Junagadh Agro Biotech . Navsari Agricultural University, Navsari . National Research Centre in Medicinal and Aromatic plants . Genome Research Centre, Baroda . National Research Centre for Groundnut . L.M. college of pharmacy Banaskantha . B.V. Patel PERD (Pharmaceutical Education and Research Development) Pharma Biotech Centre . Nirma Institute of Pharmacy . Centre for Salt and Marine Chemical Research Institute (CSMCRI) Gandhinagar Marine Biotech . Department of Marine Sciences, Bhavnagar University Ahmedabad . Department of Bioscience, S.P. University . The National Institute of Occupational Health . Department of Microbiology, MS University of Baroda Rajkot Anand Environment Vadodara Biotech . Department of Microbiology, Gujarat University . Department of Life science, Bhavnagar University . Gujarat Ecological Education and Research Foundation Junagadh Bhavnagar . Cancer Research Institute, Ahmedabad Medical Biotech . Genetics centre Ahmedabad Navsari . Department of Microbiology and Biotechnology, MS University of Baroda Biotech . Department of Biotechnology, Hemchandracharya, North Gujarat University Engineering . Department of Biochemistry, MS University of Baroda . Department of Food and Nutrition, MS University of Baroda . MSc in Bioinformatics, Gujarat University . Sardar Patel University, Vallabh Vidhyanagar . MS University of Baroda . Bhavnagar University, Bhavnagar Bioinformatics . Saurashtra University, Rajkot . Indian Institute of Advanced Research, Gandhinagar . Sikkim Manipal University, Ahmedabad Study centre . Bioinformatics Institute of India, Ahmedabad Study centre Source: Gujarat State Biotechnology Mission

30 Research Areas of some Major Institutes

Government / University Research Institutes

National Research Centre for Central Salt and Marine Sardar Patel University Genome Research Centre Medicinal and aromatic plants Chemicals Research Institute . Structural and Functional . Genome analysis and Research focus: Research areas include: genomics bioinformatics for study of plant . Germplasm enhancement of . Cultivation of sea weeds and microbial genomes . Environmental Biotechnology medicinal and aromatic plants . Bioprospecting for Marine . Improvements in conventional . Production of parental lines and . Plant Biochemistry organisms, microbial breeder's stock breeding procedures extremophiles and . Production of transgenic plants . Human Health . Contract research bioremediation

Company Research Institutes

Zydus Research Centre Bioarc Research Solutions Cadila Pharma Research Centre . Research areas : Development . Research areas: Cell culture, Thrust Areas: of biogeneric therapeutic fermentation, downstream . Immunodiagnostics proteins, antibodies and processing, formlation . rDNA proteins for prophylaxis, vaccines research and analytical therapy and diagnosis development . Development of polyclonal . Discovery pipeline: Animal feed . Research initiatives: NDDS for antibodies supplement, diagnostic kits and proteins, cloning facility, . Isolation, purification and developing monoclonal cloning, fermentation and characterisation of biopolymers antibodies and recombinant from natural resources for purification of therapeutic products and molecular development of surgical aids, proteins and vaccines diagnostics therapeutics and prophylactics

31 Government Support

Institution Funding Incentives

• Gujarat State Biotechnology • Gujarat Biotechnology Venture • The State has proposed to provide Mission (GSBTM) has been Fund (GBVF) is set up by the State special package of incentives, on constituted to encourage new to support entrepreneurs with an case-by-case basis for mega BT entrepreneurs into biotech and initial corpus of INR 50 crore projects having an investment of attract investments in the State INR 100 crore or more

Education Policy

• GSBTM has initiated concept called mbtEACH to • State biotechnology policy 2007-2012 generate skilled human resource in the field of Bioinformatics • Under the policy, State proposes to develop • GSBTM has conceptualised GenDioT to promote and develop skilled human resource in Human sector specific biotechnology zones and parks genetics and genetic diagnosis • State proposes to promote biotech research and • Formal biotechnology education body GBioN

• Gujarat Biotechnology Cash Residential Program strengthen industry-academia linkage for students

Source: Biotechnology Policy 2007-2012, Gujarat State Biotechnology Mission

32 Gujarat Biotechnology: Enabling Environment

Biotechnology policy Business Infrastructure facilitation . BT parks . BT zones And . SEZs networking

Gujarat Biotechnology Education . PG courses Entrepreneurial . Specialised courses support . Value added courses

Biotechnology research

33 Invest in Gujarat : A world- class Business Destination

To Delhi

Banaskantha Agroprocessing, Dairy and Engineering Bio-Tech cluster Patan Mehsana Soda ash and salt- Kutch Himmatnagar Gujarat International based industries, Gandhinagar Finance-Tec City cement and steel Ahmedabad pipes Kheda Surendranagar Panchmahal Knowledge corridor Dahod 202 industrial estates Anand Industrial corridor across Gujarat (DMIC) Jamnagar Dholera Savli Biotech Park Rajkot Vadodara Petroleum and brass parts Porbandar Rajpipla Petroleum, Chemicals Bharuch and Petrochemicals Engineering and Bhavnagar Amreli Investment Region ceramics Junagadh (PCPIR) Surat

Soda ash and salt Chemicals, petrochem. based Navsari pharma, textiles and engineering Valsad 18 Captive Ports along Special Investment 55 special economic 1600 km coastline Region (SIR) zones (SEZs) across across Gujarat Gujarat To Mumbai 55 special economic zones (SEZs) across Gujarat 202 industrial estates across Gujarat

34

Biotechnology Page No. 34 Key Contacts

Gujarat State Biotechnology Mission http://www.btm.gujarat.gov.in

Gujarat Akruti – TCG Biotech Limited http://www.akrutibiotech.com

Industries Commissionerate, Government of Gujarat http:// www.ic.gujarat.gov.in

iNDEXTb - Industrial Extension Bureau http://www.indextb.com

Gujarat Industrial Development Corporation http://www.gidc.gov.in

Maps used not to scale N 35