（Appendix）

(in English)

List of Principal Investigators

・If the number of principal investigators exceeds 10, add columns as appropriate. ・Place an asterisk(*) by the name of the investigators who are considered to be ranked among the world’s top researchers. ・Give age as of 1 April 2017. ・For investigators who cannot participate in the center project from 1 April 2017, indicate the time that their participation will start in the “Notes” column.

Current affiliation Academic Name Age (organization, Notes department and degree specialties) Professor, International M.D., Ph.D. Institute for Integrative 1 Masashi Yanagisawa* 56 , Sleep Medicine, Pharmacology University of Tsukuba

Professor, International Institute for Integrative M.D., Ph.D., 2 Takeshi Sakurai* 52 Sleep Medicine, Neuroscience University of Tsukuba Professor, International Institute for Integrative Sleep Medicine, M.D., Ph.D. 3 Hiromasa Funato* 47 University of Tsukuba Neuroscience Associate Professor, Univ Toho Professor, International Ph.D. Institute for Integrative 4 Yoshihiro Urade* 63 Sleep Medicine, Neuroscience University of Tsukuba

Professor, Department of Psychiatry, University of Texas Southwestern Medical M.D., Ph.D. 5 Robert Greene* 66 Center, Neuroscience Professor, International Institute for Integrative Sleep Medicine, University of Tsukuba Associate Professor, Department of Biochemistry, Ph.D. University of Texas Genetics, Southwestern Medical 6 Qinghua Liu* 45 Molecular Center Professor, , Professor, International Biochemistry Institute for Integrative Sleep Medicine, University of Tsukuba

（Host institution： University of Tsukuba Abbreviation of the Center： IIIS） 1 （Appendix） Current affiliation Academic Name Age (organization, Notes department and degree specialties) Ph.D. Professor, International Medicinal Institute for Integrative 7 Hiroshi Nagase* 69 Chemistry, Sleep Medicine, Organic University of Tsukuba Chemistry

International Institute for Integrative Sleep M.D., Sleep 8 Makoto Satoh* 61 Medicine, University Medicine of Tsukuba

M.D., Ph.D. Professor, Occupational 9 Ichiyo Matsuzaki* 57 Faculty of Medicine, Psychiatric University of Tsukuba Medicine, Space Medicine

Professor, M.D., Ph.D. 10 Hitoshi Shimano* 57 Faculty of Medicine, Endocrinology, University of Tsukuba

Professor, Faculty of Health and Sport Ph.D., Sports 11 Kumpei Tokuyama* 63 Sciences, University of Medicine Tsukuba

Professor, Tsukuba Ph.D., Advanced Research 12 Akiyoshi Fukamizu* 57 Molecular Alliance, University of Biology Tsukuba

Professor, Laboratory Animal Resource Center, M.D., Ph.D. Department of 13 Satoru Takahashi* 55 Developmental and biology Embryology, Faculty of Medicine, University of Tsukuba Professor, Department of Neuroscience, Ph.D., 14 * 65 University of Texas Neuroscience Southwestern Medical Center

（Host institution： University of Tsukuba Abbreviation of the Center： IIIS） 2 （Appendix） Current affiliation Academic Name Age (organization, Notes department and degree specialties) Professor, Ph.D. Department of Molecular Neuroscience, Biology, 15 Carla Green* 54 University of Texas Biochemistry, Southwestern Medical Circadian Cente rhythms Professor, Department of Molecular and Ph.D., 16 Yang Dan* 49 Biology, University of Neurobiology California, Berkeley, HHMI Professor, Department of Neuropsychiatry, M.D., Ph.D., 17 Tetsuo Shimizu* 64 Akita University Psychiatry Graduate School of Medicine Professor, Graduate School of Pharmaceutical Sciences, Kyoto M.D., University 18 Hitoshi Okamura* 64 Ph.D. Professor, International Institute for Integrative Sleep Medicine, University of Tsukuba

Associate Professor, M.D., International Institute Ph.D. 19 Kaspar Vogt 50 for Integrative Sleep , Medicine, University Pharmacology, of Tsukuba Neurobiology

Associate Professor International Institute Ph.D. 20 Michael Lazarus 47 for Integrative Sleep Neuroscience Medicine, University of Tsukuba

Associate Professor, M.D., Ph.D. International Institute Brain 21 Masanori Sakaguchi 40 for Integrative Sleep regeneration Medicine, University and sleep of Tsukuba

（Host institution： University of Tsukuba Abbreviation of the Center： IIIS） 3 （Appendix） Current affiliation Academic Name Age (organization, Notes department and degree specialties) Associate professor, International Institute 22 Yu Hayashi 36 for Integrative Sleep Ph.D. Science Medicine, University of Tsukuba

（Host institution： University of Tsukuba Abbreviation of the Center： IIIS） 4