VERMONT VOL. 50, ISSUE 2 • 2013 medicineUNIVERSITY OF VERMONT COLLEGE OF MEDICINE

PROBING THE MYSTERIES OF TRAUMA Kalev Freeman, M.D., Ph.D., uses the Emergency Department as a living laboratory

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▲ Vermont Medicine Hits a Half-Century ▲ A Tale of Two Neuroscientists VERMONT

UVM COLLEGE OF MEDICINE MAGAZINE

2 From the Dean 3 College News  e Medical Education Center renamed, trauma education put to the test in Boston, a new migraine gene discovered, graduates features have their day, and more. 12 20 26

MEDICAL IRA ALLEN SOCIETY History in the making

e Medical Ira Allen Society has a long history, beginning Probing the Mysteries A 50-Year Record A Tale of Two with the Century Club, initiated by medical alumni in the of Trauma Neuroscientists late 1950s. For more than three decades the College of Few medical schools, if any, can claim Medicine has recognized hundreds of donors each year. Born in an instant of unplanned, violent a magazine with a 50 year pedigree. As A deep personal friendship and shared stress, trauma demands immediate action and Vermont Medicine hits the half-century interest in neuroscience led two ese benefactors have been the mainstay of philanthropy, is inherently di cult to research.  rough mark, we look back fondly over the  ve- longstanding chairs through two decades and their gifts have greatly impacted students, faculty, innovative data-gathering systems, one trauma decade chronicle of the life of the College of collaboration, and the merger of their and research. Just as UVM founder Ira Allen shaped UVM’s physiologist at UVM turns the Emergency of Medicine. two departments. earliest legacies, today’s Medical Ira Allen Society members Department into a living laboratory. By Edward Neuert By Jennifer Nachbur continue to mold the College of Medicine. By Josh Brown

e Ira Allen Society at UVM, and the Medical Ira Allen Society at the College of Medicine, recognize annual gifts Hall A of $2,500 and lifetime giving of $100,000 or more, with WebXtras in this issue: 31 special recognition for donors of $1 million. • View the College’s Commencement Ceremony President’s Corner • A large selection of articles and photos from the last 50 years of Hall A and Vermont Medicine, including: 32 The 1965 construction of the Given Building The rising numbers of women medical The “new” curriculum of 1967, and the students in the 60s and 70s Class Notes development of the Vermont Integrated Early computer use in the 1970s and the 33 Curriculum in 1999 dawn of the World Wide Web in the 90s Read more about the Medical Ira Allen Society at Go to: uvm.edu/medicine/vtmedicine 35 Development News uvmfoundation.org/Iraallen or call the College of Medicine Development and Alumni Relations o ce at (802) 656-4014. ON THE COVER: Assistant Professor of Surgery and Pharmacology Kalev Freeman, M.D., Ph.D., 40 Reunion ’13 in his laboratory in the Given Building. Photograph by Mario Morgado. The College of Medicine is now on Facebook and Twitter. Check in to see what's happening today! 42 Obituaries COLLEGE NEWS

VOL. 50, ISSUE NO. 2 PUBLISHED AUGUST 2013 Medical Education Center FROM THE DEAN Named for Helen and Robert Larner, M.D.’42 As spring began its turn to summer, we graduated 106 Editor Edward Neuert  e University of Vermont new physicians and two-dozen Ph.D. recipients at this announced in May that the Assistant Dean for year’s commencement. ose graduates fanned out across Medical Education Center at the country, with a good number staying a part of our Communications & Planning Carole Whitaker the College of Medicine will academic medical center community, and many more Contributing Writers be named for alumnus and going to residencies and post-doctoral programs at the Jennifer Nachbur Burlington native Robert Larner, most prestigious institutions across the country. Erin Post M.D.’42, and Helen Larner, in The Medical Education Center, above, will be renamed on October 4 for Helen and Nina Shedd tribute to the couple’s decades- Robert Larner, M.D.’42, at left. Soon after graduation comes Medical Reunion, a wonderful time to see the results of Assistant long e orts to make medical commencements past, when successful graduates return to share with us and their fellow Michelle Iasilli education more a ordable. bene tted from the Larner Endowment when they were students. alumni all the news of their busy lives and their accomplishments. is was my  rst Art Director “ e impact of the It is  tting that we honor Bob and Helen in a lasting way by “repeat” reunion — that is, I’ve now been dean of the College long enough to be seeing Steve Wetherby, Wetherby Design Larners’ generosity on the naming this important educational building in recognition of their classes return a second time. With each year, the feeling for how much our alumni value Contributing Photographers College of Medicine and the longstanding dedication to our University.” their medical alma mater deepens. Raj Chawla, Je Clarke, Alec Jacobson, physicians educated there is immeasurable,” noted UVM President Dr. Larner and his wife, who live in California, have a long Sally McCay, Mario Morgado is issue of Vermont Medicine o ers a special window into the College of Medicine. Tom Sullivan. “ eir understanding and support of cutting edge history of giving at the College. In 1985 with an initial gift of Few medical schools can claim to have a magazine whose history stretches back  ve medical education and the importance of access and a ordability for $50,000, they established the Larner Endowment and Student Loan University of Vermont decades. We are fortunate that,  ve decades ago, John Mazuzan, M.D.’54, one of our medical students has impacted many, many lives. Moreover, their Fund. Now totaling over $8 million in assets, the Fund has provided College of Medicine most committed alumni, was tapped to found this publication, then called Hall A. commitment to UVM and its students has sparked a continuous  nancial support to over 1,100 UVM medical students. It receives In these pages, and in the related material on our web site, you can see the depth of our Dean stream of philanthropy from others, including physicians who over 150 contributions annually, growing each year as recipients are history and the unchanging nature of our commitment to the missions of this College. Frederick C. Morin III, M.D. inspired to give back themselves. And if that 50-year view isn’t enough, the story of former chairs Rodney Parsons, Ph.D., Senior Associate Dean for “ The impact of the Larners’ generosity on  e Larners have also supported a number of medical and Robert Hamill, M.D., and their quarter-century of collaboration and leadership Medical Education education initiatives at UVM, including $1 million to build an William Je ries, Ph.D. underscores even more what a close-knit, supportive community we are a part of. the College of Medicine and the physicians innovative Team-Based Learning Classroom, and $300,000 to Senior Associate Dean purchase  ve cardiopulmonary simulators for the UVM/Fletcher We must note two people who are among the many who help us achieve our missions. for Research educated there is immeasurable.” Allen Clinical Simulation Laboratory.  e formal renaming of the Ira Bernstein, M.D.’82 Robert Larner, M.D.’42 and his wife, Helen, have been the most steadfast donors — UVM President Tom Sullivan Medical Education Center will take place on October 4. this institution has ever seen. eir continuing generosity, which particularly bene ts Interim Senior Associate Dean for Clinical A airs medical students and their education, is being recognized with the renaming of our Howard Schapiro, M.D.’80 Medical Education Center. We have an event planned for October 4, during UVM Senior Associate Dean for Homecoming and Family Weekend, and I hope that many of you will be able to join Finance & Administration Lakoski’s Research Finds Link Between Fitness & Cancer Risk in Men us then for the celebration. Brian L. Cote, M.B.A. A high level of cardiovascular ASCO’s o cial Press Program, a measured in a clinical setting.” Meanwhile, the work of researchers at the Vermont Cancer Center has gained important  tness in middle age reduces distinction accorded to less than  e study included more Send Us Your Stories support from the generous contributions of Arthur Perelman, M.D.’52 and his extended men’s risk of developing and one percent of abstracts from than 17,000 men who had a If you have an idea for something that family, which was commemorated with a special event on campus in June. ese and should be covered in Vermont Medicine, dying from lung and colorectal the annual meeting. single cardiovascular  tness all the other e orts of our alumni and friends help maintain the constant renewal and please email: [email protected] cancer, two of the most “While poor  tness is assessment at a mean age of improvement of our school. common cancers a ecting men, already known to predict future Visit Vermont Medicine Online 50 years. Study participants For full current and past issues according to  ndings from a cardiovascular disease, this is were divided into  ve groups and exclusive webXtras at: large, prospective 20-year study. the  rst study to explore  tness according to their measured www.uvm.edu/medicine/vtmedicine Better  tness also reduces the as a marker of future cancer  tness performance. Researchers risk of dying from, though not risk prognosis,” said Lakoski. analyzed Medicare claims data developing, prostate cancer. “ is  nding makes it clear that to identify the participants who Frederick C. Morin III, M.D. Lead study author Susan patients should be advised that had developed lung, colorectal, Dean, University of Vermont College of Medicine Lakoski, M.D., assistant professor they need to achieve a certain or prostate cancer over a median Susan Lakoski, M.D. of medicine, presented these  tness level, and not just be follow-up period of 20–25  ndings at the American told that they need to exercise. years.  ey found that the risk Society of Clinical Oncology And unlike exercise behavior, of being diagnosed with lung or the most  t, relative to those Vermont Medicine is published by the University (ASCO) Annual Meeting in which relies on patient self- colorectal cancer was reduced who were the least  t. Fitness of Vermont College of Medicine. Articles may be Chicago, Ill., in June. Lakoski’s reporting,  tness can be by 68 and 38 percent, was not found to signi cantly reprinted with permission of the editor. Please send address changes, alumni class notes, letters to research was also selected for objectively and accurately respectively, in men who were impact prostate cancer risk. the editor, and other correspondence by visiting: 2 VERMONT MEDICINE www.uvm.edu/medicine/vtmedicine UVM Med Photo VOL 50, ISSUE 2 • 2013 3 Letters on an COLLEGE NEWS Notables COLLEGE NEWS Exceptional Teacher Training Helps Save Lives at Schneider Appointed Director of Cardiovascular Cushman Appointed to AHA Research Institute National Board of Directors

ssistant Professor Emeritus Dallas Boushey Dallas Boushey’s house A on Shelburne Road in Burlington stands square and stately, a reminder of a time decades ago when this was a mostly residential district, practically the outskirts of the town. Now, stores and restaurants are mixed in with the homes, and traffic Marathon Bombing whizzes by at all hours. Behind Boushey’s built a very house sits a black four-door Lincoln that has obviously not been driven in a while. Al’s French Frys is now. It was a rural Mary Cushman, M.D., Dallas Boushey is almost always home place then. We had a lot of truck farmers these days, in the house where he and his out there. We had a neighbor who raised The College of Medicine announced the over 145 publications, late wife, Mary Ann, raised four daughters. asparagus and gladiolas and used to use a At 93, his characteristic vigor is somewhat horse and wagon to bring his wares into diminished. He spends most of his day town in Burlington to peddle them. comfortably ensconced in an easy chair We were too poor for me to pay in a sunny ground-floor parlor room, tuition to Burlington High School (South with everything he needs in easy reach, Burlington didn’t have a high school back including a walker that he now uses to get then), but we were not poor enough to go special record around. His body may be weakened, but on welfare relief and get free tuition, so I his mind is still scalpel-sharp, and he can left school, or it left me, after eighth grade. M.Sc., professor trace back the memories of his nine-plus It was the Depression, so I worked lots of decades as easily as he once tracked the jobs for very little. Before I got to UVM I appointment in July of cardiologist and editorials and book blood vessels of the heart for the thousands did landscape gardening for a house near of medical students he taught during the Redstone campus for 35 cents an hour. all the years he spent in the College of You didn’t break the bank with that, or fill Medicine anatomy lab, a tenure that lasted it up either! And then I got into painting  e email to Professor of Surgery John Fortune, M.D., arrived late in the evening Facing page: Dallas Boushey and two medical students formally from 1940 to 1987, but that — sign painting for a fellow on Center examine “Killer” the skeleton in the anatomy lab in the continued on with informal stints in Street. I was learning gold-leaf lettering and 1950s. Above right: Boushey at home earlier this year; the lab well into the 1990s. getting a dollar a week at that time. I wasn’t and his honorary UVM degree. Above left: Boushey’s during his fi ve handmade model of the trachea and bronchi. making enough to put parts on my bicycle! So you might say I started out pretty small, VERMONT MEDICINE: You have and when I got to UVM it increased a bit. animals that you’re going to get? And the of medicine and some copies on the table next to you of My first job there was seven days a week for doctor said no, not really. And my uncle OF AN publications, such as Yankee, that have 15 dollars a week. said, well I got just the person for you. Professor of Medicine David Schneider, M.D., chapters, and holds ANATOMy written about you over the years. That was me. And that’s where I started. VM: So where did you start at UVM? Katie Shean. DALLAS BOUSHEY: Now that VM: And that was in the old medical of April 15. Its writer was fourth-year senior surgery major “I am sure ExTRAORDINARy LIFE story in there, in Yankee, doesn’t exactly DB: Well the College of Medicine decided building, on the corner of Pearl and In the depths of the Great Depression, a kid from the farm fields of start where I really started. that they needed an animal research Prospect? decades teaching laboratory. And the doctor that was in South Burlington with just an eighth-grade education came to work VM: Where did you start? charge heard of my uncle, who was a sheet DB: The little building next to it. I think metal worker, because they needed a lot now it’s for the Outing Club. And then at the College of Medicine. Fifty years later, he retired as an assistant DB: Most of my family was from here, of cages made for the animals — rats, they put in another building, a Quonset medical director of but I was born in Kampsville, Illinois, pigeons, you name it. So the doctor in hut, behind it, and they moved the professor of anatomy. Now in his tenth decade, in 1919. My parents were separated and charge went over to my uncle’s shop, just animals into that, but that was after my as director of the Cardiovascular Research three U.S. patents DALLAS BOUSHEY at about 6 years old I moved with my before you cross the bridge to Winooski. time. 1937 was when all this happened — shares his memories with Edward Neuert of Vermont Medicine. family to my grandparents’ house in South He was an auto body shop and a sheet when I started with the animal research Burlington. We had a little house that’s metal worker. And my uncle said to him — department. Then in 1940, the job opened at the College of still there, across the street from where you got anybody to take care of all these up in the anatomy and neurobiology you have heard about the bombing that occurred at the Boston Marathon today,” 26 VERMONT MEDICINE Alec Jacobson VOL 50, ISSUE 1 • 2013 27 the Thrombosis and Shean wrote. “I wanted to let you know that I was actually in a restaurant about Institute (CVRI). Schneider, who is director for his development Medicine, so it Hemostasis program comes as no surprise that the interview 20 feet from the second explosion site. Instead of running away, I used what you of cardiology in the department of medicine of methods that at Fletcher Allen Health with Boushey in the last issue of Vermont taught me in ATLS and tried to help the victims.” and medical director of cardiology at Fletcher address issues Care, was elected a Medicine brought forth an unprecedented ATLS stands for Advanced Trauma Life Support, a senior-year course that Allen Health Care, will succeed CVRI founding involving platelets member of the national level of response from alumni who studied every surgery major is required to take. Shean had completed her ATLS training director Burton Sobel, M.D., who passed away — components of David Schneider, M.D. Mary Cushman, M.D., M.Sc. Board of Directors of with him during his years as an active three weeks prior to the marathon. “Part of ATLS was a section on mass trauma,” this spring. Recruited to UVM/Fletcher Allen in blood that assist the American Heart Association (AHA), e ective faculty member, and during voluntary she recalled recently, “and I thought, when am I ever going to see mass casualties?” 1994, Schneider’s innovative discoveries have with clotting. The CVRI, which was launched in May 1, 2013. The AHA is the nation’s oldest, teaching stints in his retirement. On the afternoon of the marathon, Shean and some friends had tried to get helped to better determine bleeding risks after 2002, engages nearly 30 investigators across largest voluntary organization devoted to  ghting an outdoor seat at the Forum restaurant on Boston’s Boylston Street, the exact invasive procedures and reduce the incidence 16 specialty sections, including cardiovascular heart disease and stroke, and is second only to Thank you so much for that fantastic piece on Dallas location where the second of two bombs that detonated that day had been placed. of dangerous clotting. He has an active clinical imaging, coronary artery disease, diabetes and the federal government in money spent to fund Boushey. We had always heard about his legendary  ere were no seats available, so the group instead took indoor seats at another practice and robust research program with heart disease and interventional cardiology. cardiovascular and stroke research. A fellow of the story from Pat Powers and Bruce Fonda, but your restaurant, Max Brenner, one storefront away from Forum and about a block from AHA, Cushman is an international expert in the  eld piece was so comprehensive...a truly Vermont story the race’s  nish line. of cardiovascular disease epidemiology. She has of success and recognition. I’ve written a letter to When the  rst bomb detonated down the street at 2:49 p.m., the crowd in DeStigter Inducted as ACR Fellow served in a number of national, regional and local Mr. Boushey to thank him for all he contributed to Max Brenner’s got suddenly quiet, but it wasn’t clear at  rst what the noise meant. leadership roles for the organization since  rst my education as a surgeon. His models were truly “I decided I would go see what was going on,” said Shean. She was just reaching Associate Professor Meeting and Chapter Leadership Conference in volunteering for the association in the 1990s, after incredible and were crucial for my learning. the door to the sidewalk when the second bomb exploded. Crying, frantic people of Radiology Kristen Washington, D.C. in May. Fellows demonstrate receiving her  rst grant from the AHA in 1996. — JoAn Monaco, M.D.’01 immediately began pushing into the restaurant to take cover. Shean fought against DeStigter, M.D., was a history of service to the College, organized the tide and found her way outside.  ere she found puddles of blood, and several inducted as a fellow radiology, teaching, or research. Approximately I read with much interest and a little tear in my eyes people whose lower limbs had been blown o . Looking down, she saw a severed in the American 10 percent of ACR members achieve this the article about Dallas. I began medical school foot sitting in the street. College of Radiology distinction. DeStigter also serves as vice chair (ACR) during the of radiology and is a radiologist at Fletcher Allen Mawe Receives International three weeks late, taking the place of someone who She quickly collected belts and scarves from bystanders, and began placing GI Disorders Research Award decided it was not for him. I don’t have to tell you tourniquets on victims and replacing tourniquets that had been improperly placed organization’s Annual Health Care. how di cult it was to catch up in all the courses. But the  rst time.  e ATLS course had included a scenario where students get to a Kristen DeStigter, M.D. Professor of Neurological I had a secret weapon for anatomy: Dallas Boushey. bombing site and have to assess and treat very quickly  ve injured victims. Shean Sciences Gary Mawe, He and I spent quite a few one-on-one sessions continued to do just this on Boylston Street, focusing on the victims who were Ph.D., was one of eight over the cadaver. To this day, I know it was the one in the worst shape. At least one of those victims was killed by the bomb. Many Parsons Honored with ATS Distinguished Achievement Award researchers honored at area where I actually got ahead of some of my others survived with life-changing injuries. the 10th International The American Thoracic Society (ATS) presented joined UVM/Fletcher classmates. Dallas deserves every honor that can “I just want to say thank you for teaching me how to handle a trauma,” Symposium the 2013 Distinguished Achievement Award to Allen in 2000 as be given to him. He has my thanks, respect and best Shean wrote in her email to Dr. Fortune several hours later, after she had left the on Functional E.L. Amidon Professor and Chair of Medicine director of pulmonary wishes for good health. site and driven away Gastrointestinal Polly Parsons, M.D., at the organization’s and critical care from Boston. “I Disorders held in Gary Mawe, Ph.D. — Robert J. Hobbie, M.D.’65 annual meeting, held in Philadelphia, Pa., in medicine, and chief did all I could and Milwaukee, Wisc., in May. The award is given to individuals who of critical care it allowed others April. The International Foundation for Functional have made outstanding contributions to services. She was When I began anatomy, our group of four (all to help those who Gastrointestinal Disorders (IFFGD) gave Mawe the  ghting respiratory disease through research, appointed chair of Vermonters) pulled out our cadaver. It was a could be saved.” award in the Senior Basic Investigator category for education, patient care, or advocacy. Parsons medicine in 2006. woman who had been my aunt’s long time renter Shean began Polly Parsons, M.D. his work in the area of chronic digestive disorders. in Bennington. I had known her since I was a little her residency in kid. I stepped back, surprised that she had even general surgery in died, let alone donated her body. Dallas came over, July at St. Elizabeth’s Former Governor Dean Speaks on Healthcare smiled, and veri ed that indeed it was she. We Medical Center in Decreasing spending and improving health care quality and outcomes — the goal of the all decided to defer her for another class. He was Boston. On May 14, Accountable Care Organization model — were among the health care reform issues discussed by sensitive, understanding, compassionate — brilliant at Senior Honors special guest speaker Governor Howard Dean when he spoke to an over ow crowd at the College and humble. All of those attributes make him a Night, she received of Medicine on the evening of April 25 as part of the Spring 2013 Community Medical School series. remarkable educator and person. the Pilcher Award, This free public lecture program is presented jointly during fall and spring semesters by the College — Jim Betts, M.D,’73 presented by and Fletcher Allen Health Care. Katie Shean, M.D.’13, right, receives the Pilcher Award from Professor of Dr. Fortune. Surgery John Fortune, M.D. Former Governor Howard Dean, M.D., makes a point during his April 25 lecture.

4 VERMONT MEDICINE Andy Duback UVM Med Photo, Mario Morgado, Alec Jacobson VOL 50, ISSUE 2 • 2013 5 COLLEGE NEWS Research Notebook COLLEGE NEWS Another Clue Revealed for the Mystery of Migraine Study Probes Genetic Link to Estrogen Responsiveness, Cipolla Potential Impact on Fertility Identifi es New A team co-led by Robert E. Shapiro, M.D., 1 delta (CK1δ).  e group Biomarker Research from Emma Wall, Ph.D., postdoctoral earlier this year, Ph.D., professor of neurological sciences, subsequently found a second for Brain associate in immunobiology, and Cory has implications for has discovered a new gene for migraine, family whose members also Injury during Teuscher, Ph.D., professor of medicine and infertility treatment, a disabling headache disorder that a ects had ASPS along with migraine, Preeclampsia pathology, o ers insight into the genetic and evaluation of up to 60 million Americans each year.  e and who also had a mutation pathways underlying responsiveness to risk for endometrial One of the three leading study, published as the cover story in the in CK1δ, but one that was estrogens and their potential role in fertility, cancer. Findings may causes of maternal May 1, 2013 edition of the journal Science di erent from the mutation Marilyn Cipolla, Ph.D. postmenopausal bone loss, and sensitivity also help to inform disease and death Translational Medicine, prompted news found in the Vermont family. to environmental chemicals that disrupt environmental health worldwide, preeclampsia can lead to kidney coverage from National Public Radio,  e investigators created mice the body’s endrocrine system. The study, policy. and cardiovascular damage, as well as seizures USA Today, CNN, and other outlets. with the Vermont family’s Emma Wall, Ph.D. published online in The FAS B Journal (called eclampsia) and brain injury. Research by “Searching for genes is potentially a CK1δ mutation which proved Marilyn Cipolla, Ph.D., professor of neurological very productive angle to understanding to have sleep/waking behaviors sciences, and colleagues sheds light on a what causes this brain state and therefore comparable to ASPS, as well new biomarker for brain injury in early-onset what might lead to potential therapies,” as multiple behavioral and Higgins & Sigmon Co-Edit Journal Supplement Focused on Incentives & Health preeclampsia (EPE) — oxidized low-density Shapiro said in an interview with the physiological changes strongly lipoproteins (LDL). Having a biomarker for those Burlington Free Press May 15. associated with migraine, Professor of Neurological Sciences Robert Shapiro, M.D., Ph.D., has Stephen Higgins, Ph.D., professor of at risk for brain injury could impact treatment While migraine often runs in families, including heightened sensitivity discovered a gene that is key to the development of migraine. psychiatry and psychology, and Stacey and prevention options as well as delivery only a handful of genes have so far been to touch and temperature. Sigmon, Ph.D., associate professor of decisions in women with preeclampsia. The identi ed that confer some susceptibility Taken together, the studies of families psychiatry, served as co-editors and study appeared in the March 2013 issue of The to variants of the disease. Shapiro and with two di erent human CK1δ mutations Shapiro, a neurologist at Fletcher contributors for a special supplement to FAS B Journal. colleagues initially identi ed a Vermont and the observations of mice with one of Allen, is a national leader in the research the journal Preventive Medicine, titled family with multiple members who these mutations, provide evidence that and treatment of migraine. He founded “Incentives and Health.” The supplement was experience migraine along with an unusual altered functioning of CK1δ can increase the Alliance for Headache Disorders focused on a model developed by Higgins sleep/waking disorder called Advanced susceptibility to migraine.  ese  ndings Advocacy, a consortium of 12 nonpro t that uses  nancial incentives to reward Tracy and Sleep Phase Syndrome (ASPS). Researchers open new lines of investigation towards an organizations with particular concerns for Stacey Sigmon, Ph.D. and Stephen Higgins, Ph.D. healthy behavior. Other UVM contributors to Colleagues found a mutation in a ected members of understanding of the causes of migraine headache disorders. the supplement include Philip Ades, M.D.; Tara M. Higgins,  rst-year medical student; Find Increased this family in a gene called casein kinase and possible new therapies. Ira Bernstein, M.D.; Diann Gaalema, Ph.D.; Mollie Patrick, predoctoral fellow in psychiatry; Heart Attack Hugh Garavan, Ph.D.; Sarah Heil, Ph.D.; Evan Laura Solomon, Ph.D.; and Karen Weierstall, Risk in HIV Hermann, predoctoral fellow in psychiatry; research project assistant in psychiatry. Infected Arthur Perelman, M.D.’52 and Family Establish $1 Million Fund for VCC Individuals A study of more than Russell Tracy, Ph.D. A 1952 alumnus of the College of Medicine Arthur J. Perelman, M.D.’52, of day to honor such a beautiful person. She Wood Research Examines History-Taking in Primary Care 80,000 veterans by and his family have established a $1 million Summit, N.J., sons Robert, Jon, and Carl wanted to make a real di erence, and she Russell Tracy, Ph.D., professor of pathology Marie Wood, M.D., professor of medicine, participants. Their and biochemistry, and colleagues, shows endowed fund at the university to support and their families established the knew that the Vermont Cancer Center was director of the Familial Cancer Program, study concluded the work of the Vermont Cancer Center at Charlotte E. Perelman Cancer Research the place she could do that.” that increased heart disease risk may be an and Vermont Cancer Center (VCC) member, that although there unexpected side e ect of the potent combination UVM and Fletcher Allen Health Care. Fund in honor of their late wife, mother Vermont Cancer Center Directors delivered a talk on “QOPI Family History Study were high rates of and grandmother. Nearly  fty family Claire Verschraegen, M.D., and Gary antiretroviral therapy “cocktails” used to treat and Recommendations” at the American documentation for HIV. The paper Tracy coauthored, published in members and friends were on campus June Stein, Ph.D., along with UVM College of Society for Clinical Oncology (ASCO) Annual  rst-degree family 22 to celebrate the gift and honor the late Medicine Dean Frederick Morin and John JAMA Internal Medicine Online First, analyzed 2013 Meeting held in the  rst week of June history, there were low data from veterans infected with HIV and those Mrs. Perelman. Brumsted, President and CEO of Fletcher in Chicago, Ill. Wood notes that family history rates of documenting Mrs. Perelman had a keen interest Allen Health Care, were at the celebratory uninfected. Results showed that HIV infection of cancer is an integral part of screening family member age Marie Wood, M.D. in the work of the Vermont Cancer event to o er thanks on behalf of their is associated with a 50 percent higher risk of guidelines to identify patients who are at high at cancer diagnosis, heart attack even after adjusting for recognized Center and her husband’s alma mater. institutions and speak on the impact of the risk of colorectal or breast cancer and is among which is “such an important feature for cancer  e Perelman family designated the gift. In acknowledgement of the family’s cardiovascular risk factors. Although the source the referral criteria for genetic counseling diagnosis,” Wood notes. “I would argue that of increased risk isn’t known with certainty, fund to support a wide range of research, gift and the legacy of Mrs. Perelman, a and testing. However, many primary care we can and should be doing better.” Patients educational and advocacy activities. painting by Helen Shulman, the Perelmans’ a di erent but related study demonstrated and specialty physicians are “not very good” referred for genetic testing receive counseling that chronic, well-controlled HIV infection “My family and I are delighted to make niece, entitled “With a Following Wind,” at actually documenting it in practice, Wood and discuss the results with appropriate this gift to the Vermont Cancer Center in and memorial plaque were unveiled in is associated with a level of in ammation says. Wood and her colleagues used ASCO’s documentation, the analysis revealed. However, consistent with increased cardiovascular honor of our beloved Charlotte,” said Dr. the Medical Education Center near the Quality Oncology Practice Initiative (QOPI®) to rates of referral for both counseling and testing Perelman. “ is was our wish together, and entrance to the Dana Medical Library. disease risk. Arthur Perelman, M.D.’52, at center, with family members assess family history taking and referral for are low. “Referral rates must be higher, as this and VCC administrators. I am so happy to share in this remarkable genetic counseling and testing among QOPI really does a ect cancer care,” says Wood.

6 VERMONT MEDICINE UVM Med Photo, Jeff Clarke UVM Med Photo, Mario Morgado VOL 50, ISSUE 2 • 2013 7

COLLEGE NEWS STUDENT NOTES COLLEGE NEWS 3 QUESTIONS New Student Achievement Award Inaugurated for Christa Zehle, M.D.’99 At the College of Medicine’s annual Honors Night Associate Dean for Student A airs and Associate Professor to recognize student achievement, held May 14, of Pediatrics at the UVM College of Medicine the College presented a new award: The Mildred A. Reardon, M.D. Award for service to the College Dr. Zehle, an alumna of the UVM College of Medicine Class of 1999, joined UVM of Medicine. Mayo Fujii, M.D.’13 the inaugural and Fletcher Allen Health Care in 2003 as assistant professor of pediatrics, and winner, is a Vermont native who received an undergraduate degree in neuroscience from was promoted to associate professor in 2011. She successfully launched the Middlebury College. She graduated in May and Pediatric Hospitalist Program at Fletcher Allen, and continues to have a clinical will complete her residency in General Surgery role at Vermont Children’s Hospital along with her responsibilities as Associate at Fletcher Allen Health Care in Burlington. The award is named for Professor of Dean. Inducted into the Alpha Omega Alpha Honor Medical Society in 2008, Medicine Emerita Mildred A. “Mimi” Reardon, M.D.’67, who has for decades been a Zehle is a sought-after mentor by medical students and residents, and has driving force in serving the health care needs of Vermonters. received numerous awards for teaching. She has been honored twice by residents as Clinical Attending of the Year and was nominated for the award  ve Neill Presents Project at Clinton more times, garnering runner-up honors in her  rst year at UVM/Fletcher Allen. Student-run Literary and Arts Global Initiative University Recently, she was also runner up for the Clinical Attending of the Year selected Journal Publishes 2013 Issue Conference by medical students. Christa Zehle, M.D.’99 The Clinton Global Initiative University Conference  e College of Medicine’s publication for the literary and attracts celebrities, political leaders, and social activists visual arts, e Red Wheelbarrow, began its history in the from around the world. This year, medical student 1990s, and has appeared periodically over the years. Now, a Luke Neill, Class of 2016, was there with his childhood student-run initiative is seeking to continue that tradition on a friend, Sam Meyer, to present text messaging software more regular basis.  e journal is named after physician-writer they are developing. Their HIPAA-compliant software VM: What is the your main VM: After medical school, our VM: How has having been program allows patients to enroll at the pharmacy and receive text messages role as Associate Dean for graduates go on to residencies a medical student here William Carlos Williams’ famous 1923 poem. Williams, born in that help them understand their medications and health implications. At this 1883, was one of the leading American poets of his generation, year’s conference in St. Louis, Missouri, in April, their project was recognized Student A airs? here in Vermont and across the infl uenced your role? all while running a busy solo general practice for 40 years in as an exemplary approach to addressing a global public health challenge, and nation. What role do you play Paterson, N.J. they met former President Bill Clinton and his daughter Chelsea. in that next step? Students Matthew Lin ’16 and Nicholas Sinclair ’16 headed up the e ort, founding a student interest group with eight other 155 Miles Later: Med Student Sets volunteers.  e 2013 issue of e Red Wheelbarrow, featuring Record for Indoor Rowing CZ: My main duty is to ensure that we CZ:  e second important piece of CZ: I don’t think it’s necessary to have work by students, faculty, sta , and alumni of the College, is 1 2 3 educate and train high-quality, excellent my job is providing the support and been a student here to succeed in this job, available online at the website of the O ce of Medical Student At about 12:30 p.m. on January 5, 2013, medical student Cornelia Willis, Class of 2016, started rowing physicians. And I want to make sure that resources for our students’ applications to but I think it’s been a very important factor Education (www.uvm.edu/medicine/mededucation). on the machine in her apartment. She didn’t stop until we’re providing the support and resources residency programs, and overall advising. for me. I had an excellent experience here 1 p.m. the next day, breaking the world record for the so that the students’ experience over the All our students know that they want to as a student. I’ve valued that experience longest continual row for her age group. She also broke four-year curriculum is a really positive be physicians, but settling on the type of even more than my undergraduate years. the record for distance traveled in 24 hours as tracked I catalogued each Perhaps most important, I hope you know that I’ll keep the following: pinpoint freckle, hairline wrinkle you reminded me to be mindful The part of me that learned from you one. It’s my team’s responsibility to ensure physician you want to be can be a very I’ve always felt strongly about teaching that road-mapped your dust covered back. of the little things. to listen for the softer sounds - So this is what it feels like Because the thing about the little things, the pit-pat of my sweat to be a cartographer, twice removed. things that make life excellent, hitting the ground when I walk home. by Concept 2, the manufacturer of her machine and To learn the names make life good, The part of me that learned from you of so many parts, but not the whole. is that sometimes they’re too small. to look around every now and then — academic success for each student, or to di cult decision. Some people enjoy and education, and to be able to return bear witness to a thousand tiny universes From you, for the first time Small, they get lost in the valleys and mountains created by the distillation of wind and retrospection. a standard-setter in the industry. The e ort produced some awe-inspiring I learned what it meant to be quiet. of our finger prints; You taught me to speak buried and fossilized The part of you that rekindled in me in the absence of words: in the banks of our nail beds. my faith in all things strange, kind and unknown. provide the resources that students need everything they encounter in the clinical to my home state, and my home medical Language spelled out by All of this numbers: Willis burned over 12,000 calories. Her hands alone — pulling the 16 immense negative spaces. when we try to hold on to them too tightly. 17 Diction through the vacuums The upside of this is that they’re still there, that pull and fill unseen, but surely a part of us. the skeletal backbones “oars” on the rowing machine more than 30,000 times — travelled over 17 miles. to be academically successful. Sometimes, settings, and that can make it really a hard institution, to teach and to impart the of the A’s, E’s, I’s, O’s and U’s we learn from birth. With this, we joked late nights without the certain comedy of consonants. Told secrets, without the vigilance of vowels. In the end, she rowed 250,013 meters, or 155.35 miles, in 24 hours 31 minutes not often, that doesn’t work out — just choice. Some develop a strong liking for lessons I’ve learned and the experiences MATTHEW LIN | UVMCOM 2016 lessons HAND (X-RAY AND PHOTO MANIPULATION) | CHUCK SCHMITT | UVMCOM 1989 and 12 seconds. When Willis isn’t on the rowing machine, she’s on the water with because you get into medical school doesn’t one particular pathway, but maybe it’s I’ve had to today’s students — well, there’s the best women rowers from across the country. Last year she was a member mean that you’ll be able to meet all of the a struggle for them to be competitive in nothing quite like helping to educate of the U.S. National Team and will be trying out again. Her sights are set on the requirements and successfully graduate, that  eld. And some people will question the next generation of physicians. Being World Championships in South Korea in September, where she hopes to once again represent the U.S. in the lightweight women’s quad. so we also oversee the advancement whether they made the right decision. So able to do that at the institution where why write? committee, which determines if someone career advising is really big part of what you’ve trained, for me, has an extra-special I don’t have time to write this now, but if I don’t write it now, it will be lost. is demonstrating satisfactory academic we do. I spend a lot of time meeting with meaning. Many things have de nitely It’s a thought, no, a feeling, which is produced by the reading. I should have delayed the reading until I had time to respond, but the desire is strong to 36 ingest the thoughtful prose of another. I cannot write fast enough. For the 37 immediate response to the reading is most genuine and is often altered by further thought. progress, and plans for students who might students and doing individual advising, and changed since my student days, but the

My experience has been that the writing process is the most powerful; the meditative thought that precedes it and the reading that follows are not nearly as passionate. The organizing of thoughts and feelings, the desire to STEPHEN BELL | UVM CARDIOLOGY RESEARCH express and communicate, and the drive to complete it, are all part of the be struggling. So my o ce is responsible I de nitely enjoy that piece. I remember collaborative nature of the College of packing process that allows me to move on. Until it is done, I am distracted and constrained. The thoughts and emotions prior to writing are powerful, but seem restless and random. The often inflated anticipation of reader response is later tempered by less than engaging reviews. They cannot possibly reproduce through imagination, what I have understood through for academics, providing support and having a challenging decision when Medicine has stayed the same.  ose INTERDIGITATING (ELECTRON PHOTOMICROGRAPH OF GLOMERULAR PODOCYTES) | PAMELA GIBSON, M.D. experience, but that does not hinder me in the process. It must be written. resources to those students, and also deciding that I wanted to be a pediatric who work in the College really value and The latest issue of The Red Wheelbarrow contains poetry, prose, and visual art by overseeing the committee that reviews all hospitalist. I’ve always known I made the respect education and are excited to be members of the College community. students. right decision, and I want to help our here teaching. students get to that same place.

8 VERMONT MEDICINE Photographer Name, Photographer Name At left: UVM Med Photo, Cornelia Willis. Above: Mario Morgado VOL 50, ISSUE 2 • 2013 9 COLLEGE NEWS

Tampas Receives Honorary UVM Madeleine Kunin and John Hennessy, Jr. Degree

For half a century, John Tampas, M.D.’54 has shown UVM President Thomas Sullivan, J.D., and tireless dedication to the John Tampas, M.D.’54 College of Medicine both as a professor of radiology and an active alumnus. At the university’s main commencement ceremony on May 19, this dedication was recognized with an honorary Doctor of Science degree from the institution. In addition to his 1954 medical degree, Dr. Tampas received his bachelor of science from UVM in 1951. He joined the Class marshal Shetal Patel, M.D.’13 UVM faculty in 1962 and chaired the Department of Radiology from 1970 to 1996. Medical students twice named him UVM Teacher of the Year, and he has served for years on several alumni groups and as president and executive secretary for the Medical Alumni Association (MAA). In 1995, Dr. Tampas received the A. Bradley Soule Award, the MAA’s highest honor for a medical alumnus. An endowed faculty position — the A. Bradley Soule, William Hopkins, M.D. M.D.’28 and John P. Tampas, M.D.’54 Green & Gold Professor COMMENCEMENT 2013 of Radiology — funded by the radiology faculty, recognizes the A total of 106 STUDENTS were conferred medical degrees by atmosphere of the College of Medicine, and urged his fellow contributions of both men and their legacy at the College. UVM President Tom Sullivan, J.D., and Dean Rick Morin, M.D., at graduates to remember that feeling with every patient they the College Commencement Ceremony in Ira Allen Chapel on encounter in the years ahead. Also in attendance were former May 19. UVM/Fletcher Allen cardiologist and Associate Professor Vermont Governor and U.S. Ambassador Madeleine Kunin and her of Medicine WILLIAM HOPKINS, M.D., gave the main address, in husband, John Hennessy, Jr. Lyden which he recounted the value of mentors and colleagues in his The new physicians went o to residency programs at career, including the late Professor of Medicine Burton Sobel, prestigious institutions across the region and nation. About one Addresses M.D. JEFFREY MCLAREN, M.D.’13 presented the student address. out of every eight members of the Class of 2013 will remain in New Ph.D. McLaren expressed his appreciation for the unique and caring Vermont for residency training. Graduates

On Saturday, May 18, graduate students from across the David Lyden, M.D., Ph.D.’86 University of Vermont received diplomas and hoods in the Graduate College Commencement Ceremony at the Patrick Gymnasium. Among them were graduates of programs a liated with the College of Medicine in the areas of biochemistry, cell and molecular biology, microbiology and molecular genetics, pharmacology, molecular physiology and biophysics, clinical and translational science, and neuroscience. In total, 27 Ph.D. students from the College of Medicine were recognized at the ceremony. Another eight received a Master of Science degree. David Lyden, M.D., Ph.D.’86, the Stavros S. Niarchos Chair View the 2013 Medical Commencement Ceremony online. and an associate professor of pediatrics and cell and developmental The ceremony was streamed live, and you can watch a biology at Weill Cornell Medical College and a pediatric neuro- recording and see more photos of the event. oncologist at Memorial Sloan-Kettering Cancer Center, was the guest Go to: uvm.edu/medicine/vtmedicine speaker. Lyden was recognized last fall with the Distinguished Graduate Je rey McLaren, M.D.’13 Alumni Award from the UVM Medical Alumni Association.

10 VERMONT MEDICINE Andy Duback, Paul Reynolds, Sally McCay VOL 50, ISSUE 2 • 2013 11 PROBING THE MYSTERIES OF RAUMA Through innovative data-gathering systems, a UVM trauma physiologist turns the Emergency Department into a living laboratory.

by Josh Brown | photographs by Mario Morgado

12 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 13 elen White,* a twenty- collecting blood. Freeman steps out to who is now the chief medical o cer for three-year-old skateboarder, talk with her. “We are going to draw Fletcher Allen. “I knew that there was a Dr. Freeman has been able to develop an grits her teeth and lets out blood from her for the study,” Freeman very strong clinical program in emergency a deep grunting moan. tells Manning. “We’ll enroll her. I medicine, but almost no research arm,” outstanding research program for emergency Her knuckles look like think she’s going to get admitted. Head Freeman recalls. “My  rst love is science, hamburger meat. She has bleeding? Could be. I’m guessing she and I told Steve I thought I could set up a medicine and trauma using a novel model of black akes of blood on her lower lip and broke some of the bones in her face. trauma research program with a shoestring around her nose, a curving laceration She’s pretty crunched.” budget.” Le er wanted to know how. student research assistants. across her forehead, and two glistening  en he sits down at a bank of Modeled on a program at the University — Steven Le er, M.D., UVM Professor of Surgery and gashes in her knee. computers to order some tests for his new of Pennsylvania, Freeman told him, “My Chief Medical O cer, Fletcher Allen Health Care A white-and-orange cervical collar trauma patient. A surgeon strides by in plan is to build an infrastructure using holds White’s head still, but her eyes blue scrubs. More EMTs wheel around undergrad students as a team.” move back and forth as two EMTs in the corner with a bed, pushing an elderly Unlike most medical schools and green jumpsuits wheel her into a room patient the color of ash. Like a chorus of Level 1 trauma centers, UVM and on the main oor of the Emergency electronic frogs, there’s a constant beeping Fletcher Allen are surrounded by Department of Fletcher Allen Health and ringing in the air from telephones undergraduate students, with many Care in Burlington. and monitors. pre-med and science students eager Kalev Freeman, M.D., Ph.D., leans It’s not exactly the quiet, peaceful to get experience in a clinical setting. over the stretcher to look White in the environment a scientist might hope for to Several UVM dorms literally look out eye. “I’m Doctor Freeman. You’re going do research, or a professor might hope for on ambulances arriving at the emergency to be okay,” he says very gently, as a team to instruct college students. department. “We have this unique pair of nurses and technicians pull up trays of But Freeman, who is an assistant of institutions in Vermont where we have supplies. “We’ll get you feeling better here.” professor of surgery and pharmacology, undergrads right around us. Let’s tap in to Freeman turns to one of the nurses, director of Emergency Medicine this motivated young workforce and have Sheena Fisher, R.N., who is adjusting an Research, and the lead investigator of them help us,” Freeman told Le er, who IV line. “Let’s do a hundred of fentanyl,” the Trauma Physiology Laboratory at helped him get started. he tells her and then turns back to his the UVM College of Medicine, does So far, the students have gathered patient. “We’re getting you some medicine both. He conducts research and teaches data for 22 studies, both for Freeman and to help with your pain.” undergraduates and medical students — for other researchers across the College  e EMTs report that White collided right in the emergency room. of Medicine. with a streetlight and fell, face- rst, In return, his research on trauma Le er is impressed by what Freeman over a small concrete wall in downtown — particularly traumatic brain injury has built. “He has been able to develop Winooski. No helmet. “Where are you and blood clotting — depends on the an outstanding research program for hurting, my friend?” Freeman asks. 24-hour-a-day, 7-days-a-week e orts of Emergency Medicine and Trauma using a “My head hurts so bad,” White tells undergraduate students (and a few recent novel model of student research assistants. him, groaning again, and her eyes drift graduates, like Manning) enrolled in two up to a monitor overhead, beeping out a courses he founded: Surgery 200 and 201. record of her breaths and beating heart. Since 2008, he’s had hundreds of students “I’m looking to see what needs stitches,” — in four-hour shifts as the required he says, peering closely at his patient’s lab for the courses — working alongside forehead. But Freeman is more concerned him and other doctors in the emergency about what he can’t see: what might be room, screening and enrolling patients for happening inside White’s skull. clinical studies. “ ey’ll be here at 3 a.m. “Are you able to sit still for a few on a holiday weekend,” he says. pictures?” he asks. “We’re going to take Freeman received his undergraduate some pictures of your head and then we’ll degree from the University of Michigan get you stitched up.” White grunts and gets before earning his M.D. and Ph.D. from whisked down the hall for a CAT scan. the University of Colorado and performing Just outside White’s exam room, a residency in emergency medicine at recent UVM graduate Chelsea Manning, Boston University. When he arrived in At left, a Fletcher Allen Emergency Department team who’s now working as a research assistant Vermont in 2007, he approached Steven practices the kind of trauma situation that results in a blood sample collection. Chelsea Manning, above, in the Department of Surgery, has been Le er, M.D., then head of UVM/Fletcher collected samples and data both as a student and a waiting quietly. She’s holding a vial for Allen’s Division of Emergency Medicine, research assistant.

14 VERMONT MEDICINE * Helen's name and case details have been changed to protect her privacy. VOL 50, ISSUE 2 • 2013 15  is innovative program has been great for  at’s why, just before midnight, problems. Some clot too easily; some don’t In the little lab, Manning spins our patients, academic medical center, and Chelsea Manning is still waiting outside clot well at all. “Trauma surgeons would the blood in a centrifuge and then runs the students.” of Helen White’s examination room.  e love to have this information,” Freeman samples into two machines that will patient has returned from her CAT scan says, “before they begin to operate.” measure its clotting characteristics. “Here and Manning is hoping that a technician we can see how quickly it clots,” she says. With this team, Freeman’s research aims will soon return her vial,  lled with On a computer screen a thin line spreads to understand the relationship between White’s blood. If White gets admitted While Chelsea Manning waits, out into a wide blue band. “ at’s where traumatic injury and blood vessels. Several to the hospital overnight, she’ll qualify Freeman and a medical student sit in the clot is starting,” Manning says, as the of his studies focus on the endothelium for one of the trauma studies Freeman the blue gloom of an image viewing data streams out, forming a bell-shaped — the inner lining of blood vessels that is helping to lead, with a team of other room, looking at glowing scans of Helen pair of curves, beautiful and orderly. regulates smooth muscle, helps form researchers and universities, on the White’s head and spine. “ e big risk Trauma, on the other hand, is, almost blood clots, and provides a barrier to biochemistry of blood clotting. Manning’s for her is bleeding. She’s gotten facial by de nition, disorderly and unpredictable. uid that could leak in the brain. But in job as one of Freeman’s student “chiefs” — trauma, so I’m looking to see if she’s got A blinding rush of headlights. A leg blown trauma the biochemical signals in the having completed the two surgery courses any blood inside the skull,” he says, as o by an IED under your Humvee. A endothelium can go haywire, Freeman and now working for him before applying he scours the ghostly grey images for sudden rending of our gossamer plans by believes, which leads to a cascade of other to medical school — is to take the blood telltale bright-white patches behind the an intrusive, painful snap. “ is is why medical problems. from the technician and go to a tiny lab eye sockets or between bone and brain. we haven’t  gured out the answers to Many physicians think of trauma as just o the trauma bay in the ER.  ere, “You can see she broke her nose here,” many trauma questions, because it is so a mechanical problem requiring a surgical Kalev Freeman, M.D., Ph.D., reviews imaging of a possible head trauma with UVM student research assistant she’ll prepare it for study, to see how fast he says pointing to an unhappy-looking challenging to study; you can’t plan for Heidi Considine in the Fletcher Allen Health Care Emergency Department.  x. Broken bones can be set, amputated and  rm it clots. angle in the picture. “But I don’t see any it,” Freeman says, “ ese are people in the limbs reattached, lacerated skin stitched. “Most of the time there would be threatening bleeding in the skull,” he says. worst of circumstances, in the middle of But brain damage from swelling and the acute brain injury on systemic endothelial simply bleed to death. For some reason, another student here to collect the blood “ at’s good.” the night, and we have to work fast. It’s failure to e ectively form blood clots are function,” Freeman writes. In other words, many severely wounded people can’t form sample, and I’d be prepping everything A few minutes later, Manning steps very hard to get this data. It’s simply a complex problems of vascular biology when a car crash victim with a head blood clots — and Freeman would like to back in the lab, but since I’m on by in the room. “I’m ready to do the blood,” feasibility challenge. An emergency room that defy surgery.  ey’re problems that injury dies of a heart attack a week later, know why. myself tonight I’ll do both,” she says.  e she says. “I’m on call all night; do you is a very di cult environment to do robust involve the endothelium — and they’re it may be because “the cardiac tissue was “You’d think we could just give these study, led by UVM biochemists Kathleen want me to stay with her and do the two- scienti c research.” two of the primary reasons people die damaged by brain trauma. All the blood patients blood transfusions. No one should Brummel-Ziedins, Ph.D., and world- and four-hour draws? Do you think we’re An additional challenge: Freeman after severe trauma. vessels are a ected by the stress of a brain ever die from bleeding, because we can give renowned blood expert Kenneth Mann, ultimately going to use her blood?” needs Helen White’s permission to Every 23 seconds someone in the injury,” Freeman says. them blood!” Freeman says. “But they just Ph.D., aims to get a clearer sense of the “I’m not sure if she’s going to have participate in this clotting study. Informed U.S. sustains a traumatic brain injury, And there’s a similar lack of can’t make a blood clot.”  ere are several natural history of coagulation in trauma an admission injury,” Freeman says, “but consent is a foundation of all ethical the Centers for Disease Control and knowledge about uncontrolled bleeding, theories about why this happens: massive patients.  eir goal: start to develop let’s go ahead and run the blood sample medical research. But how do you get Prevention reports — about 1.7 million one of the major causes of mortality infusions of red blood cells and plasma pro les and possible biomarkers for and get this piece of data and log it. I’ll consent from a patient who just smashed people each year, resulting in 52,000 in trauma. Of U.S. soldiers injured by change the biochemistry of the blood’s people who are going to have coagulation know before midnight.” her face on the concrete? Or worse. “When deaths. Many of these deaths come hours, combat, most of them — 88.9 percent natural clotting mechanisms. Saline someone is bleeding out from everywhere days, or weeks after the initial trauma according to the Army Institute of infusions dilute blood proteins. Dropping and they’re on a ventilator, how can you and are often triggered by failure of other Surgical Research — die on the battle eld. body temperature and build-up of acid get them to sign a consent form to take a body systems outside the brain. “ ere But of those combat injuries that were may contribute. Genes matter. Freeman blood sample?” Freeman asks. is a fundamental knowledge gap in our “potentially survivable,” Freeman says, would like to show how dysfunction of the You can’t. And yet understanding understanding of the long-term impact of more than 90 percent of soldiers who die endothelium is also a culprit. what’s happening with critically injured “We’ve already  gured out most of the patients — just after they’re injured, in possible surgical procedures for trauma, real time — is some of the most important If we can understand what is going but sometimes you stitch up all the holes work in emergency medicine.  at’s why and they’re still bleeding out and there’s Freeman developed special protocols with on with blood vessels after trauma, then not much you can do about it,” he says. the ethics committees of the university “What is there after mechanical surgery?” and hospital. He got permission to get a we can target therapies to help protect Freeman asks. His answer: “Better waiver of consent to take an initial blood biochemistry.” sample from trauma patients. “ en we them and thereby bene t blood clotting “If we can understand what is going don’t do any analysis or reporting on that capabilities and prevent brain swelling. on with blood vessels after trauma,” data until we go back to the patient and get Freeman says, “then we can target their permission,” Freeman explains, “once therapies to help protect them and thereby they’ve recovered.” If they’ve died? “We go — Kalev Freeman, M.D., Ph.D., Assistant Professor of Surgery and Pharmacology, Director of Emergency Medicine Research bene t blood clotting capabilities and Research assistant Abby Wager prepares blood samples as Dr. Freeman observes. Because blood from trauma victims must to a family member and we’ve got thirty prevent brain swelling.” be processed soon after their injury, Freeman built an analysis facility in a former closet at the Emergency Department. days to get consent from the family.”

16 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 17 One could be forgiven for imagining Kalev Freeman saying, “I’m only a real doctor; I don’t play one on TV.” His blue eyes, athletic chin, impish smile, and Gen-X tattoos, barely visible beneath a short-sleeved shirt, might make the cut in Hollywood. And after hearing his slow, gu awing laugh, one could see how he considered a di erent career as a bluegrass  ddler. But spend more time with the man and it becomes clear that here is someone with remarkable drive and sense of mission. “When you’re in the hospital, it’s like Music and the Mind running the marathon,” Freeman says. (He Whether sleeping or sprinting, the healthy would know, having run several editions body has an amazing ability to keep When a soccer player with a concussion comes into the emergency room at Fletcher of the Vermont City Marathon, including constant blood ow to the brain. Allen Health Care, medical student ALEX THOMAS’17, would like to catch him. And, maybe, one where he  nished an overnight shift Testing brain and gut arteries in the emergency room at 7 a.m. and toed from animal models, Freeman and his encourage him to listen to music on his iPod. the starting line downtown at 8 a.m.) “It’s students are exploring how the molecular a very high-intensity activity and I can signaling mechanisms in endothelium, hroughout his undergraduate years at Concussions can produce a range of symptoms symptoms — but the research team saw forget about my lab work while I attend particularly calcium pathways, can UVM leading up to his entrance into the such as headaches, depression, slowed reaction low activation of brain areas associated with to patients.” mis re after a traumatic brain injury times, memory loss and sleep problems. But memory tasks in the patients who didn’t recover T College of Medicine, Alex Thomas has But most days, Freeman wakes up — leading to excessive dilation in the been helping a team of researchers led by beyond these cognitive, behavioral and emotional quickly from their injury, Thomas reports, thinking about his next experiment, he brain and blood vessels. With his mentor, Professor of Psychiatry Magdalena Naylor, M.D., clues — often self-reported — there is no method “whereas there is high activation in those who At top: frequent group meetings give the large research says. And most of his time, other than University Distinguished Professor Mark Ph.D., and emergency medicine specialist and of detecting a head injury in mild cases. will go on to recover and the control group.” team a chance to share ndings. Above: student presenters compare notes before the start of a group meeting. Assistant Professor of Surgery Kalev Freeman, In 2011 and 2012, Thomas and other In other words, in addition to nding his four shifts a month in the Emergency Nelson, Ph.D., chair of the Department M.D., Ph.D. — who are working together to students taking Freeman’s Surgery 200/201 physical evidence of concussions, the Department, is spent on the third oor of of Pharmacology, Freeman has been better understand what’s happening in the courses helped recruit patients with researchers hope that this study may point the Given Building, conducting animal collecting data showing that endothelial animatedly to a radiologist on one brains of patients su ering with mild traumatic concussions to be part of the Head Injury toward techniques that would be predictive studies on the physiology of brain injury. cells are hyperactivated following trauma, of several phones he’s assigned in the brain injuries. Naylor and Freeman are also Testing and Outreach Program (HITOP). Using of who is likely to go on to have long-term Unlike the emergency room, the lab is as a wave of calcium ions move in.  is emergency room. Helen White, it turns testing the idea that people with concussions an advanced MRI machine near the Emergency symptoms — or develop the post-concussive predictable and the work methodical. “You blast of calcium could be a cellular out, is not going to be admitted as an might recover better and faster with Department, the researchers tested 28 of syndrome increasingly seen in NFL players and can always count on the rats to be there at foundation for both swelling of brain in patient to the hospital. Her injuries mindfulness training — a cognitive-behavioral these volunteers soon after their injury and recent combat veterans. 10 a.m.,” he says. tissue and loss of clotting capacity. hurt, but they’re not as serious as they therapy — that uses music as a focusing tool. then seven days later using a state-of-the-art Those patients who still had symptoms He can also count on several hard- Using high-speed video images  rst looked and her head now seems  ne. technique called di usion tensor imaging after a week were invited into the second Of the 1.7 million traumatic brain injuries working students too, like Tram Tran from powerful spinning-disc confocal Some stitches, wound scrubbing, pain in the United States annually, about 1.4 million The team has been looking at the brain’s stage of the study: a six-week program of (UVM’13) and Alex  omas, a Class of microscopes in Nelson’s nearby lab, medications, and she’ll be heading home. are mild, otherwise known as concussions. white matter — axons — to see if shearing mindfulness training supervised by Naylor, who or swelling can be detected, giving a new directs UVM’s Mind/Body Medicine Clinic. The 2017 medical student. “As a freshman in Freeman and his team can observe and “We got the  rst blood sample, which view on mild brain injuries. This imaging is patients met once a week to learn meditation the UVM Honors College, Tran contacted measure calcium, nitric oxide, and other we can use in the comparison group,” very sensitive, and the team hopes to detect and focusing techniques that the researchers Freeman to see if she could help in his signals that move into and through Freeman tells Manning. But because the damage of bers where other techniques can’t. believe can help injured brains recover. lab. He put her to work right away, and, endothelial cells.  eir hope is to help patient is being discharged, she can’t be in The study also tested the patients’ brains at A major focus of the sessions: cognitive four years later, she has become a star point the way toward treatments that the main trauma study. And in that, Helen work, using functional MRI imaging, looking at exercises with music. Young men are major biochemistry student, completing her could block key calcium ion channels, White, lacerated, sutured, and sore, could blood oxygenation levels in several areas of the su erers of concussions, but they are much undergraduate thesis under Freeman’s turn o overabundant calcium signals, and count herself fortunate. brain’s gray matter while the patient worked on, less likely than women to participate in supervision and preparing to apply to maintain clotting pathways: in short, calm “I work in the lab all week,” Freeman for example, a memory task. traditional group therapy. “It’s tough getting medical school. “He’s amazingly dedicated the endothelium. In the long run, Freeman says, “ en I go work a shift in the E.D. On both types of imaging, the researchers NFL guys to sit in group therapy,” Freeman to his students,” says Alex  omas. would like to contribute to long-sought and see someone on Friday night, someone found signi cant di erences between control says, “but iPod therapy could work. These are Above all other tasks, the body seeks therapies for uncontrolled bleeding and in a car accident, with the same injury that patients and those with concussions. Another cognitive exercises, focusing, for example, on Top: Kalev Freeman, M.D., Ph.D. works with medical to send the right amount of blood to the traumatic brain injuries. we’re modeling and studying.  at brings important nding: in the hours right after a certain sounds like a horn or drum beat. It’s like student Alex Thomas’17 and UVM student research brain, feeding its delicate oxygen-gulping But this night, in the hospital, it home. It reminds me why we’re doing assistant Tram Tran. Above: Professor of Psychiatry concussion, many patients have the same a mind gym.” Magdalena Naylor, M.D., Ph.D. network of vessels, neurons, and memories. it’s approaching 1 a.m. Freeman talks the research.” 

18 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 19 trapped into a passenger alumnus complain that “the College only seat of a twin-engine aircraft contacts me when it wants my money.” Sa few hundred feet above “ at’s not true anymore,” said Maeck, White Plains, N.Y., John Mazuzan, pointing at Mazuzan. “He’s going to start M.D.’54, certainly had no time to producing a College magazine to keep think of the next 50 years stretching you informed.” out ahead of him. Having another “And that’s how it all began,” says 50 minutes guaranteed would have Mazuzan. “Within a few months I was been more than enough. laying out the  rst issue at the old Lane It was the spring of 1964, Press building on Pine Street, standing and Mazuzan, who’d only next to the Linotype machine.” Mazuzan recently returned to Burlington wasn’t sure what to call the magazine so, as to practice anesthesiology, a placeholder, he slugged in the title “Hall had joined a group of College A,” the name of the College’s main lecture of Medicine alumni that hall. “I couldn’t come up with another called themselves the “alumni name by press time, so we just kept it in,” raiders,” as they crisscrossed he says. Fifty years later that magazine, now the nation soliciting their fellow known as Vermont Medicine, stands as one graduates in the e ort to raise of the oldest continuously published medical funds to complete the College’s school magazines in the nation. building program, which would Mazuzan was the obvious choice to eventually produce the Given spearhead founding a publication since, as Medical Alumni complex. On he puts it, “It was well-known that I had this particular evening, Mazuzan printer’s ink in my blood.” His father had accompanied John Maeck, M.D.’39 owned and edited the North eld (Vt.) News and Win Eddy, M.D.’45, on a round & Advertiser for many years, and young of visits to alumni in New York City John had grown up running proofs in the and Hartford.  eir day done, the group shop, and writing short news and sport took o from Westchester County Airport pieces from his early teens. He had even at midnight, bound for Vermont. One engine of the small plane soon sputtered, and their pilot skillfully turned back and landed safely. Assuring his passengers that it had only been an easily solved problem of water vapor in their fuel line, the pilot quickly made some adjustments, and they were once again airborne. “ en I turned to John Maeck in AS V RMONT M DICIN HITS the seat beside me,” recalls Mazuzan, “And I said ‘why is he yelling Mayday?’” THE HALF-CENTURY MARK, “Listen,” said Maeck. It was more a matter of what couldn’t be heard: the WE LOOK BACK FONDLY engine had now completely failed.  ey A 50 YEAR again turned back. After one harrowing OVER THE FIVE-DECADE missed pass, the plane  nally bumped CHRONICLE OF THE LIFE OF down safely on the runway.  e shaken  group switched to a car. A few weeks later, on another Written at the Mazuzan kitchen table and laid out at a THE COLLEGE OF MEDICINE Pine Street print shop, the rst issue of Hall A appeared RECORD fundraising visit, the team heard a fellow in the fall of 1964.

20 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 21 Facilities Over 50 years, the College’s campus has not only changed — it’s actually covered General Eisenhower’s visit to moved. Early issues of Hall A detail Curriculum the plans for the Given complex and, Norwich University in 1946 for the paper, in 1968, the move to the top of the Change is a constant in medical education, and nothing has been more and had seen his write-up go national on hill — including the last class in the of an indicator of the constant re nement and improvement of the art the Associated Press wire. old Hall A that had served the school and science of medicine than the continuing evolution of the College’s “I don’t know how I took on creating for more than 60 years. Later years curriculum over the past 50 years. In 1967, the “new” curriculum introduced a magazine and still maintained a full-time saw coverage of the connection to a radical change: early clinical experience. That spirit continued to inform practice,” he says. He soon began to receive Rowell Hall, and the rise of the Health the curriculum development process over the coming decades, eventually some help from the University’s public Sciences Research Facility and the fostering the Vermont Integrated Curriculum’s development in the late relations o ce, but stayed on the magazine’s Medical Education Center. 1990s and early 2000s. Through all those years, the nation’s need for more masthead as editor until the late 1970s. physicians drove the size of the student body to more than double. Five decades after the  rst issue rolled

vermont o the presses, the magazine has gone ▲

through several editorial and production 1965 University of v ermont College of m ediC ine changes. Originally an 8-inch square, it moved up to a full size publication in the early 1980s. Color came to its pages in 2001, as did a name change, since in practice Third-Year Students in the readership had broadened to include their Clerkships

ALs O FEATUr ED:

 Dr. Susan Wallace Studies recipients who had never sat in the Hall A DNA Damage & Repair  Palliative Care in Focus lecture hall, which itself became a thing of ▲ ▲ ▲ spring 2009 1969 2000 2005 ▲ ▲ ▲ the past a few years ago. ( e alumni news 1999 1999 1967 and notes section, in tribute, retains the old lecture hall name.) In the following pages, and through Students Read All About It! articles available on the Vermont Medicine More than anything else, alumni of the College always wish to be kept informed of what it is See the full stories featured here, plus many added articles from the last 50 years. website, readers can get a glimpse of the like to be a medical student today. Across all the “todays” of the last 50 years, the magazine ▲ Go to: uvm.edu/medicine/vtmedicine changing life of the College of Medicine has shown students throughout their daily life — navigating the worlds of the lecture hall and 1999 from the 1960s to today. Even more clinics, learning about the physician’s life, and having a lot of fun along the way. important are the clear indications of what hasn’t changed — the work to educate students and produce research that serves Women patients and the community. It seems almost impossible to realize — Ed Neuert now, but in the 1960s it was headline- Editor, 1998–present worthy to state that “A Medical Student… is Not Always a ‘He’.” Women had rst been admitted to the ▲ College in the early 1920s, but their 1971 numbers in the student body had never been large. Beginning in the ▲ mid-1970s that changed fairly rapidly. 1972 One female student featured in the 1970s was Casja Nordstrom (later Casja Schumacher, M.D.’74), who went on to years of service on the Medical Alumni Association Executive Committee, ▲ including service as the rst female 1977 president of the committee. (Her two daughters also earned their M.D.s at the College.) Today, as has been the case for many years, roughly half the During a recent interview, John Mazuzan, M.D.’54, the student body are women. founding editor of the College of Medicine’s magazine, looks ▲ ▲ ▲ over an early issue of Hall A in his Burlington living room. 2004 1968 2004

Ed Neuert

22 VERMONT MEDICINE ▲ 1997 VOL 50, ISSUE 2 • 2013 23 Technology First and foremost comes the human dimension of medicine: the doctor/patient relationship. But augmenting that is the tremendous tide of technological innovation that has brought forth astounding new Clinical Practice resources for better treatment and increased access The delivery of medical care has changed in many ways over the last 50 years. to and sharing of information. Physicians are lifelong Medicare and Medicaid were introduced a year after the magazine was founded, and learners, and that has been apparent in these pages. the huge changes over the years in practice structures, the introduction of new clinical Computers made an early appearance, the World Wide elds such as emergency medicine, and the continuing need for more primary care Web was born right before our eyes, and in the new doctors have been documented in Hall A and Vermont Medicine. millennium, the College of Medicine Educational Tools (COMET) became a 24/7 platform for medical student Rita Pinard’s health and health care improved when her physician’s practice became a medical home. learning and sharing. Clinical simulation became a Vermont is helping to change the face of primary care with strong presence in the past decade. a new model that makes a medical practice the home for all a patient’s needs. Clinicians and researchers from the College of Medicine are playing integral roles in these efforts.

t was a cold day in January when Rita Pinard’s doctor told her what she didn’t want to hear. “You have diabetes,” Pinard recalls her saying. “If your numbers don’t go down in three months, vermont vol 49, issue 1 • 2012 we’ll need to start you on medication.” Pinard, 57, of St. Johnsbury, was close to tears at the news. She had been told she was pre-diabetic in the

University of v ermont College of m ediC ine past, but somehow that fact had never really sunk in. Fortunately for Pinard, her diagnosis coincided with a transformation in the way care ▲ ▲ ▲ is delivered in her community. Her physician’s practice was recently 1968 1974 1995 recognized as a patient-centered medical home — a model of care by Sona Iyengar | photography by Raj Chawla designed to provide seamless coordination of services.

Mission ▲ in Mind ▲ A look in detail at the accomplishments of faculty, 2009 1973 staff and students across the College of medicine ALSO FEATURED: ❯ Student experience in Guatemala ❯ r esearch Projects Deliver

▲ ▲ ▲ 1997 2007 2012

Research One of the great stories in U.S. medicine over the last ve decades has been the growth of the National Institutes of Health and other funding agencies, and the resulting growth of research work at medical schools throughout the ▲ ▲ ▲ nation. An article in a 1966 issue of Hall A told of the College’s winning one 2006 1986 1979 of the rst ve federal grants for regional heart disease, cancer, and stroke programs — an early e ort at translating the latest medical knowledge into clinical practice. As the College’s research funding has grown, stories about Faculty those e orts have frequently appeared in the magazine. There is no recognized formula for a successful medical school, but if it had to be reduced to a mathematical equation, that would certainly involve adding an intelligent and curious student body to a dedicated, knowledgeable, and caring faculty. Many members of V ermont the College faculty have been celebrated in these pages through the decades — people who helped form the physicians of today, and U NIVERSIty OF V ERm ONt COLLEGE OF mEd ICINE whose reputations and in uence continue. 

Managing Read All About It! Chronic Pain

▲ ▲ 2003 Magdalena Naylor, M.D., Ph.D., See the full stories featured here, plus many finds out where it hurts, and what makes it stop 1966 added articles from the last 50 years. alSO FEa TURED:

❯ There’s No Place like medical Home ❯ A new Heart for the Medical Campus Go to: uvm.edu/medicine/vtmedicine ▲ Fall 2009 ▲ ▲ 2009 2001 1974

24 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 25 by Jennifer Nachbur | photographs by Mario Morgado A TALE OF TWO NEUROSCIENTISTS A DEEP PERSONAL FRIENDSHIP AND SHARED INTEREST IN NEUROSCIENCE LED TWO LONGSTANDING CHAIRS THROUGH TWO DECADES OF COLLABORATION AND THE MERGER OF THEIR DEPARTMENTS.

long the bays and beaches of member recruited to the Department of designed, with Alpert’s permission, the Long Island shoreline, Molecular Physiology and Biophysics by an eight-credit, two-semester a vibrant mix of land and then-chair Norman Alpert, Ph.D., Parsons integrated anatomy and physiology sea creatures captivated the specialized in neuromuscular function. course to teach non-medical, A attention of a little boy so  e common garter snake provided an non-physical therapy students, deeply that he knew by the age of seven optimal model for studying the molecular including those enrolled in the he would one day be a biologist. A couple activity of this function, so Parsons ran ads two-year nursing program, and of hours to the north, in a town east of in the local paper, got a permit to catch medical technology and graduate Hartford, Conn., the son of a widowed them, and enlisted the help of his children technology programs. Physiology Irish maid grew to be an accomplished and neighbors’ kids to  nd these research and Anatomy and Neurobiology athlete who loved coaching children in “subjects” in order to study the synaptic faculty each taught half the course. basketball and other sports. Some forty properties of two types of muscle  bers. Parsons and Steven Freedman, years later, their paths would cross in Ph.D., had previously co-designed Burlington, Vt., when they began laying We built our two the integrated medical student the foundation for what would, in 2012, neuroscience course used at the become the Department of Neurological departments together College until the launch of the Sciences at the University of Vermont. with common interests. Vermont Integrated Curriculum Animals still  gured prominently in the early 2000s. in the mind — and career — of Rodney We thought of it as a “ ere was only limited Parsons, Ph.D., when he arrived at UVM research in the anatomy in 1967. Fresh from a National Institutes mechanism to increase department back in the of Health (NIH) postdoctoral fellowship recruitments, to build seventies,” says Parsons, and at Columbia College of Physicians and there were only about  ve Surgeons, coming to Vermont was a bridges. faculty and one-and-a-half kind of homecoming for the Middlebury — Rodney Parsons, Ph.D. administrative sta in the College alumnus and his wife. He’d department when he became chair. followed through on his early interest,  ings changed, administratively, in It was then that he began to build the and received a biology degree, and then 1979, when Parsons became the chair of theme of neuroscience, changing the moved clear across the country to Stanford the then-Department of Anatomy. While department name to Anatomy and for graduate school before returning to medical, physical therapy, and neuroscience Neurobiology. Originally he promised his native New York.  e third faculty students already had an anatomy course, he then-Dean William Luginbuhl, M.D., Longtime colleagues, collaborators, and close friends Robert Hamill, M.D., left, and Rodney Parsons, Ph.D.

26 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 27 that he’d serve in the chair’s position for birthplace of basketball, volleyball, exercise research group of about 20 people and faculty to talk to each other. As a result,  ve years. His  rst recruit was the late physiology and the YMCA.  anks to enjoyed functioning as their “coach,” they brought faculty member Margaret Bruce Fonda, M.S., a lecturer in anatomy scholarships from his hometown and the hailing back to his original career Vizzard, Ph.D., and later Felix Eckenstein, and neurobiology who was trained by college, Hamill was able to attend. “It really aspirations at Spring eld. In the early Ph.D., on board in Hamill’s department, longtime anatomist Dallas Boushey, who was a life-changing experience,” he says. 1990s, he reached a turning point in and Rae Nishi, Ph.D., in Parsons’. was set to retire after 50 years’ service. Also At Spring eld, he mastered anatomy and his career; he’d been asked to run the “Basic science was small here,” says among Parsons’ early hires was Jerome physiology, biomechanics, and — critical University’s Center on Aging, and Parsons, who recognized the value of his Fiekers, Ph.D., his former postdoctoral to his future path — the brain’s role in colleagues were submitting his name for and Hamill’s collaboration from both a fellow. Over the next twenty years, Parsons movement. After two years, Hamill had chair positions at other institutions.  en research perspective, as well as in the realm THE PARSONS FILE hired nearly twenty more faculty members, set his sights on graduate school, but one he received a letter from UVM. With his of integrated education. “Neuroscience THE HAMILL FILE Rodney Parsons, Ph.D. many of whom remain in the department fateful summer afternoon, a friend’s father deep love of his native New England, the evolved out of other basic science Robert Hamill, M.D. today. Among them was Cynthia Forehand, — a physician — pulled him aside and o er from UVM, which included service disciplines,” he adds. As the  eld grew, ACADEMIC APPOINTMENTS Ph.D., professor of neurological sciences asked him to consider medical school.  e leadership at the then Medical Center he recruited to meet correlating needs, ACADEMIC / CLINICAL APPOINTMENTS Professor of Neurological Sciences, 2013–present and current interim dean of the Graduate suggestion clicked, and he switched to Hospital of Vermont, was the only one he seeking out researchers who could also Professor of Neurological Sciences Emeritus, Professor and Co-Chair, Department of Neurological College, who took on responsibility for pre-med. His senior year, he was accepted seriously considered. teach. Among them were Drs. Gary Mawe, 2013 to present Sciences, 2012–2013 Professor, Department of Neurological Sciences, increasing the scope of the medical student to Wake Forest College’s Bowman Gray “When I came here, I think there Cynthia Forehand, Diane Jaworski, and Professor and Chair, Department of Anatomy 2012–2013 and Neurobiology, 1979–2012 neuroscience course after Freedman’s School of Medicine and, despite more were six of us,” says Hamill, whose new Victor May. Ellen Black, Ph.D., had been Professor and Chair, Department of Neurology, Professor of Physiology & Biophysics, 1973–1979 departure from UVM.  nancial hurdles, the dean of students at department included pediatric neurologist Parsons’ graduate student before he hired 1993–2012 Assoc. Professor of Physiology & Biophysics, 1969–1973 Parsons chaired the search committee the school arranged for a full scholarship. E. Stanley Emery, M.D., who had been her to teach anatomy. After Freedman left, Physician Leader — Neurologist-in-Chief, Neurology Health Care Service, Fletcher Allen Health Care and University of Assistant Professor of Physiology & Biophysics, that brought former Chair of Neurology Hamill was on his way. acting chair; Rup Tandan, M.D., recent Parsons increased the scope of Forehand’s Vermont Medical Group, Burlington, Vt., 1995–2012 1967–1969 Robert Hamill, M.D., to the College in At Wake Forest, Hamill fell in love interim co-chair of neurological sciences responsibilities to include the College’s Professor of Neurology, Neurobiology and Anatomy, and Postdoctoral Fellow in Physiology, Columbia University, 1993. Parsons’ wife had recently passed with both his wife — whom he married Timothy Fries, M.D., Joseph McSherry, neuroscience course. Medicine, University of Rochester School of Medicine and National Institutes of Health, 1965–1967 away, and the two became close friends, his second year — and with neurosciences M.D., Ph.D., and the late Antonio Gomez, Hamill’s and Parsons’ translational Dentistry, Rocheser, N.Y., 1980–1993 with Parsons often serving as Hamill’s and neurology. He spent three years in the M.D. In addition, the late Herbert Martin, science-building theme migrated into EDUCATION EDUCATION “chef” during his Burlington visits. Navy after medical school, then completed M.D., who had retired, was still seeing the curriculum as well. When Hamill 1965: Ph.D., Physiology, Stanford University, 1964–1968: M.D. Bowman Gray School of Medicine, Stanford, California  ey had much in common, including a two-year residency in internal medicine patients part-time. “ ere was limited arrived, the neurology rotation was an Wake Forest University, Winston-Salem, N.C. 1962: A.B., Biology, Middlebury College, the loss of their fathers in early childhood, at Strong Memorial Hospital in Rochester, clinical research and there weren’t any elective, not mandatory.  at status 1960–1964: B.S., Spring eld College, Spring eld, Mass. Middlebury, Vermont but Hamill’s path to UVM was longer, N.Y. A three-year neurology residency NIH grants when I came,” Hamill says. shifted when a movement led by and originated from an unexpected and a four-year NIH research fellowship Hamill’s arrival coincided with the graduating medical students pushed for ■ University Scholar, 1990—1991 starting point. in developmental neurobiology led him early stages of the founding of what the addition of a neurology clerkship.  e ■ 1996–2012: Best Doctors of America ■ Director of the COBRE Center for “I wasn’t even going to go to college,” to New York City, where he studied with would become Fletcher Allen Health Care, development of the Neural Science course ■ Spring eld College Distinguished Neuroscience Excellence grant says Hamill, whose family had emigrated world-class clinical and basic science and additional recruitment plans were in the Vermont Integrated Curriculum Alumnus Award, 2012 from Ireland before his birth. His father mentors at Cornell, and honed his research halted. “ ose were some challenging also augmented the role of neurology later became ill and passed away while expertise in Parkinson’s disease. years,” admits Hamill, who would do four faculty, and Hamill expanded his faculty, AWARDS AND HONORS Hamill was still a boy. He and his mother,  e Hamill family moved to months of hospital service each year, and clustering them around the areas of systems AWARDS AND HONORS 1989–1996 Jacob Javits Neuroscience Investigator Award who worked as a maid near their home Rochester, N.Y., in 1980, where he ran the clinics — M.S. and Stroke — and neuroscience and neural development to Teacher Investigator Development Award, NIH, (NINCDS), 1965–1967 National Institutes of Health Postdoctoral in Manchester, Conn., were what he served as a professor of neurology at the started a Parkinson’s clinic to keep the enhance medical student education. 1978–1980 Fellowship in Physiology, Columbia University Jordan Research Fellowship, National Paraplegia describes as poor. But despite his  nancial University of Rochester. A clinician, teacher department viable.  e two chairs’ joint work also had a Foundation, 1977–1978 disadvantages, Hamill had two things going and researcher, he ran the Alzheimer’s  e concept for a translational science signi cant e ect on research at the College. SELECTED RECENT PUBLICATIONS National Research Service Award, NIH (NINCDS), for him: he was a skilled athlete, and he Center and headed the neurogerontology department grew out of Hamill’s and “ e NIH COBRE grants [Center of 1976–1978 The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: implications was bright. Despite his mother’s urgings to division, as well as neurology at Monroe Parsons’ close camaraderie. “We built our Biomedical Research Excellence] have really Alfred P. Sloan Foundation Fellowship, 1975–1976 for neural control of cardiac excitability. Journal of learn a trade (he studied auto mechanics), Community Hospital. He had built a two departments together with common been instrumental in strengthening the Molecular Cell Cardiology, 2012. his high school guidance counselor had interests,” says Parsons, who recalls the concept of cross-campus neuroscience, and SELECTED RECENT PUBLICATIONS Autonomic dysfunction and plasticity in micturition other plans for him. evolution of the idea beginning with him, have formed support for the importance Predictors of cognitive outcomes in early Parkinson re exes in human a-synuclein mice. Developmental disease patients: The National Institutes of Health Neurobiology, 2012. “He gave me Middlebury, Williams, What de nes Rod Hamill and John Evans, Ph.D. — then of having a translational science program,” exploratory trials in Parkinson disease (NET-PD) Pretreatment with nonselective cationic channel Brown, and Worcester Polytech catalogs,” executive dean of the College of Medicine. he says. While Parsons and Forehand experience. Parkinsonism Related Disorders, 2010. inhibitors blunts the PACAP-induced increase in guinea Parsons as a chair is his says Hamill, who told the counselor, “I “We thought of it as a mechanism to were the Neuroscience COBRE principle Ca eine and progression of Parkinson’s disease. pig cardiac neuron excitability. Journal of Molecular Clinical Neuropharmacology, 2008. Neuroscience, 2012. really can’t go to any of these. I wouldn’t outstanding support of increase recruitments, to build bridges,” investigators, the translational core was A Pilot Clinical Trial of Creatine and Minocycline in Galanin expression in the mouse major pelvic ganglia  t in.”  e counselor didn’t let up, and Parsons shares.  e two knew that run jointly by Hamill, whose combined Early Parkinson’s disease — 18 month results. during explant culture and following cavernous nerve his faculty in all aspects Clinical Neuropharmacology, 2008. transection. Journal of Molecular Neuroscience, 2012. through conversation teased out that heightened competition and the need to clinical-basic science background  t the Hamill would consider becoming a do more translational work supported their role perfectly, and Felix Eckenstein. Subclavian artery stenosis causing transient bilateral Somatic ATP release from guinea pig sympathetic neurons of their careers. brachial diplegia: an unusual cause of anterior spinal does not require calcium-induced calcium release from physical education teacher. So he was concept, and they wanted to develop an “I’m proud of what the COBREs artery syndrome. Journal of Neurosurgery Spine, 2008. — Cynthia Forehand, Ph.D. internal stores. American Journal of Physiology Cell steered toward Spring eld College — the opportunity for basic science and clinical have done.  ey’ve supported a lot of Physiology, 2010. Interim Dean, UVM Graduate College

28 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 29  eld of Parkinson’s disease. “I now work for him — it’s a joy,” exclaims Hamill.  at’s a feeling shared by Boyd. “From my  rst days of residency to today, Dr. Hamill has been the single greatest in uence in my career development,” he says. “Discussing neuroscience with students and residents, Dr. Hamill has the excited expression of a child in a toy store. His passion for the  eld is inspiring and infectious. It has been through his mentorship and by his example that I have become the neurologist and clinical researcher that I am today.” At the College of Medicine Commencement in May, Robert Hamill, M.D., standing at left, listened while his emeritus Now 28 years past his originally citation was read by his friend and colleague Rodney Parsons, Ph.D., at lecturn. Dean Rick Morin observed at right. committed service as chair, Parsons counts running the Anatomical Donor young faculty across the campus,” says a community neurology program. Over Program with limited resources (“it was Parsons, whose role as chair has been the years, he developed a close relationship very smart to modernize and transition it similarly focused. “ e greatest thing has with Neurology Associates of Vermont, to where it is now”) and former student been watching people grow and exceed a private practice group near campus Amy McDermott’s  rst-ever-in-the-world expectations — Cindy Forehand becoming originally headed by the late Kenneth recording of neuronal synaptic currents a major support for the institution. Gary Ciongoli, M.D. He brought the physicians from bullfrog sympathetic ganglion cells Mawe, who has soared.  e development from the practice into his department among his career “highs.” of a University-wide graduate program. and initiated a shared (50/50) faculty “ e hardest part of my years as chair It’s been very satisfying.” position. When Ciongoli became ill, four was when we lost Bruce Fonda,” he admits. “What de nes Rod Parsons as a chair of Hamill’s faculty members picked up his “He was a special person, and an amazing is his outstanding support of his faculty in patients.  e department now manages the teacher. It was a loss for us all.” all aspects of their careers,” says Forehand. Associates o ce. Hamill’s early struggles are far “He supported my development as a “ e goal is to continue to recruit behind him, but not forgotten. Last year, scientist through mentoring and reviews of general neurologists to the community his alma mater Spring eld College my grant applications and supported and neurology program,” explains Hamill, who honored him as an outstanding alumnus. hall In 1905, when the College of Medicine completed its third home at the corner of Prospect and Pearl Streets in President’s Corner encouraged my interests in education and adds that the connection provides excellent Now o cially emeritus as of the Class 32 Burlington, the main lecture room was named Hall A. For the next 63 years, students (such as the members of a administration.” educational opportunities, allowing of 2013 Commencement, he says “It’s a class in the 1950s shown below) learned the science of medicine while perched on those rows of steeply-raked Class Notes 33 Along with the construction of the students and residents to experience the great feeling to start with a department wooden seats. When the College moved to the top of the hill in 1968, the designation of Hall A moved too: to a research enterprise, Hamill was busy environment of a private practice. of six and see where we’ve been able to slightly more comfortable assemblage of orange-upholstered seats on the second oor of the Given Building. Development News 35 building the clinical arm and, in particular, “I’m going emeritus this year,” says grow together.” Today’s learning environment  ts today’s medical curriculum. Students take in lectures as a class in the Sullivan Hamill, ”and we had four graduates go into Indeed, the vision he and Parsons Class Agent Directory Classroom, and they work in small group environments and in UVM’s cutting-edge Clinical Simulation Laboratory. 38 neurology — the clerkship, which is now a launched more than  fteen years ago has The settings have changed, but the mission remains the same: inspiring a lifetime of learning in the service Reunion ’13 It has been through little over three weeks long, has been a big been realized.  ey engineered a proposal of patients. This section of Vermont Medicine, named in honor of that storied hall, serves as a meeting place in 40 boost.” Most schools, he adds, only have to merge their departments into the print for all former students of the College of Medicine. Obituaries [Dr. Hamill’s] mentorship about two percent going into the  eld. Department of Neurological Sciences. 42 His department’s research productivity It was approved by the UVM Board of and by his example has been equally successful. “For a Trustees in 2012 and, in May of this year that I have become the department of our size, the amount of the newly recruited Gregory Holmes, extramural funding per faculty member M.D., took the helm. Hamill and Parsons neurologist and clinical is very high,” says Hamill. One of the couldn’t be more proud. researcher that I am research achievements of which he’s most “ e uniqueness of this department excited is the Michael J. Fox grant, which — it spans an educational realm from today. is headquartered at UVM and led by undergraduates to residents — makes — James Boyd, M.D. James Boyd, M.D., a mentee of Hamill serving as chair challenging,” says Parsons. Assistant Professor of Neurological Sciences whom Hamill proudly shares is now both “We’re glad to leave our legacy in such s s nationally and internationally known in the capable hands.”  1950 1980

30 VERMONT MEDICINE Ed Neuert VOL 50, ISSUE 2 • 2013 31

The University of HALL A | M.D. CLASS NOTES UPCOMING Vermont Foundation If you have news to share, please contact your class agent or the Development & Alumni Relations MEDICAL DEVELOPMENT & o ce at [email protected] or (802) 656-4014. If your email address has changed, EVENTS ALUMNI RELATIONS OFFICE please send it to [email protected]. For complete list of class agents, please see page 38. Interim Team Leader — Medical PRESIDENT’S CORNER Development & Alumni Relations; Vice President and Chief Operating O cer, UVM Foundation Somehow, in the midst of a soggy, wet late spring, we Shane Jacobson 1950s ’63 Neil N. Mann is currently Irwin Paradis writes: “I decided to October 4–6 managed to pull o what I think was one of the nicest working at the Center for retire from the practice of medicine UVM Homecoming & Director, Annual Giving & Major Gifts REUNION 2014: 1954 + 1959 Healthy Aging in Danvers, Mass. at the end of May of this year in Family Weekend reunions ever.  e rain held o just long enough, for Sarah Keblin order to pursue other interests such UVM Campus Marjorie Topkins reports: “I John J. (Jack) Murray received the the most part, and all the class members from across the Senior Director of Development — as historic preservation, gardening, ’50 retired Jan 1, 1996. I returned prestigious A. Bradley Soule Award October 7 decades were able to have a wonderful time here on campus Vermont Cancer Center  shing and travel. I have always to New York-Cornell Medical Center from the College of Medicine at the Alumni reception in conjunction and throughout the Burlington area. Manon O’Connor been grateful for the quality of the Sept. 1, 1998, and worked for 10 2013 Reunion. A South Burlington, with the American College education I received at UVM both Director of Major Gifts months retiring again June 30, 1999 Vt., pediatrician and retired clinical of Surgeons — Annual One thing that struck me was the span of history that our attendees at reunion re ected. In Meredyth Armitage at the undergraduate and graduate — that made 44 years in just one professor of pediatrics at UVM, Murray Clinical Congress the course of one evening, I had the pleasure of talking to Stanley Fieber, M.D.’48, who was level. This education has served me Director, Medical Alumni Relations institution. I spend my days at has served on the UVM Admissions Washington, DC well. Thank you, UVM! I met my future celebrating his 65th anniversary reunion, and later met members of the Class of 2016, who Cristin Gildea Theatre and Dance (observing not Committee and is a class agent. (All local alumni & friends welcome.) wife, Cynthia Fox, Class of 1973, as were part of the contingent of 30 current students who helped out during the weekend. It participating) and playing bridge October 9 Director, Administration Earl Nielsen is president of an undergraduate nursing student was incredible to think about the over 70-year continuum these people represented! and of course doing what most Ginger Lubkowitz ’66 the medical sta and still at UVM. We are still together 40 Graduate Student Research Day octogenarians do — going to Assistant Director, Annual and Major practicing nephrology in Morristown, years later. Our three sons and two UVM Campus I was particularly pleased to meet all the Medical Alumni Association Award winners, who physicians. Eleven and a half years Gifts N.J. His son, Craig, is a graduate of grandchildren all live out west and October 18 ago I went with my daughter and joined us for a celebratory dinner the night before the o cial opening of reunion, and was James Gilbert the medical class of 1994. want us to move out there but New Medical Student White Coat son-in-law to Vietnam where they as engaged as everyone else in attendance at the Celebration of Achievements on Friday England still holds us fast. One of our Ceremony Assistants adopted a son. I also noted with Ursel Danielson writes: “Still night, as the accomplishments of this group of distinguished alumni were detailed to the Jane Aspinall ’67 sons is also a UVM undergraduate. Ira Allen Chapel sadness the passing of Dick enjoying retirement a lot, audience, and each recipient added their thanks to the institution and their classmates. Trish Hartigan Please visit us whenever you might UVM Campus Manjoney and all the others.” spending some time travelling and attending local lectures on medicine be in our neighborhood: Hallowell, October 19  ose “thank yous” were very striking elements of the evening to me. Without exception, University of Vermont “ For some we loved, the loveliest and foreign policy or nature. My son Maine.” Medical Student Family Day these alumni credit the success of their careers and their laudable service and research to the Medical Alumni Association the best that from his Vintage rolling Richard has two children graduated Richard L. Gamelli, senior vice UVM Campus time hath prest, have drunk their cup special quality of this College of Medicine — in particular the caring, personal approach from the University of California ’74 president and provost of the October 26 ALUMNI EXECUTIVE COMMITTEE a round or two before, And one by to each student, and to each patient. You’ll often hear us speak about the need for more system. As time moves on — maybe Health Sciences Division at Loyola Alumni reception in conjunction one crept silently to rest.” scholarship aid for students, but it’s most meaningful to realize that those e orts grow O cers (Two-Year Terms) I have a chance of becoming a University Chicago, was awarded the with the American Academy of — By Omar Khayyam great-grandmother soon. It was so naturally from the tradition of support every graduate of this institution has felt over the President President’s Leadership Award from Pediatrics National Conference Mark Pasanen, M.D.’92 (2012–2014) Charles Miller writes: “Mary and nice to see many classmates at 45th the American Burn Association (ABA) Orlando, Fla. course of the four years he or she spent here on campus. reunion, looking forward to the 50th!” Vice-President I miss our classmates and close at the ABA annual meeting on April 24, (All local alumni & friends welcome.) friends the Janviers, Parkers and 2013, in Palm Springs, Florida. Gamelli If your class year ended in a 4 or a 9, and it’s been a while since you’ve been back on campus, H. James Wallace III, M.D.’88 (2012–2014) December 3 Jenys with whom we spent many is a past president of the ABA and I urge you to start planning now to come back next June, and get in closer touch with the Treasurer Alumni reception in conjunction great times together up until their 1970s currently serves as president of the with Radiological Society North memories and traditions of your medical alma mater. Paul B. Stanilonis, M.D.’65 (2012–2014) passing. It all started on the cadaver.” REUNION 2014: 1974 + 1979 International Society for Burn Injuries America Secretary John Tampas received an (ISBI). He is also a member of the Chicago, Ill. Naomi Leeds, M.D.’00, M.P.H. (2012–2014) Richard L. Teixeira writes: UVM Board of Trustees. ’54 honorary degree from the (All local alumni & friends welcome.) ’72 Natalie and I sold our home in Executive Secretary University of Vermont at its main James Gallagher is a clinical Lincoln, R.I., and have moved into an March 13, 2014 John Tampas, M.D.’54 (Ongoing) commencement ceremony on May ’75 professor of medicine at “over 55” community in East Taunton, Match Day Eve 4th Year Members-at-Large (Six-Year Terms) 19. He was honored for his “tireless Thomas Je erson Medical School in Mass. I continue to work at Lincoln Student Dinner Ernest Bove, M.D.’81 (2012–2018) dedication to the UVM College of Philadelphia, Penn., and is medical Mark Pasanen, M.D.’92 Pediatric Associates three days a Sheraton Hotel, Burlington Mary Cushman, M.D.’89 (2012–2018) Medicine both as a professor of director at Columbia County Associate Professor of Medicine week — but NO night or weekend call. March 14 Betsy L. Sussman, M.D.’81 (2012–2018) radiology and as an active alumnus.” Volunteers in Medicine. Match Day Mark Allegretta, Ph.D.’90 (2012–2016) (A photo of the presentation appears Richard H. Feins received a Robert LeGendre Jr. writes: Noon Suzanne R. Parker, M.D.’73 (2012–2016) on page 11 of this magazine.) ’73 Distinguished Academic “Thanks to Ellen Andrews for all Hoehl Gallery Omar Khan, M.D.’03 (2012–2016) Achievement Award at the College her good work.” UVM Campus Ellen Andrews, M.D.’75 (2012–2016) of Medicine’s Reunion 2013. He is a Don P. Chan, M.D.’77 (2012–2015) 1960s professor of surgery in the division Matthew Zetumer writes: “My May 18 Leslie S. Kerzner, M.D.’95 (2012–2015) of cardiothoracic surgery at the ’76 wife, Lynn, and I hang out with 2:30 p.m. Frederick Mandell, M.D.’64 (2012–2015) REUNION 2014: 1964 + 1969 University of North Carolina School Steve Lampert and Anita Feins when Graduation Ex O cio Member Bruce A. Cha ee reports that of Medicine in Chapel Hill, and is we are able. I am still enjoying private Ira Allen Chapel Dean Frederick C. Morin III, M.D. ’60 he recently remarried to Ruth recognized nationally as a “go-to practice, teaching and my work with UVM Campus JUNE 6–8, 2014 Ann Hansen, a 1958 graduate of UVM, guy” on matters pertaining to the the NFL.” and moved to beautiful Santa Fe, education of future thoracic surgeons For updates on events see: www.uvm.edu/medicine/alumni 1944 1954 1964 1974 1984 1994 2004 New Mexico. and for simulation-based training. College of Medicine graduates are 1949 1959 1969 1979 1989 1999 2 0 0 9 also members of the UVM Alumni Send Us Your Stories Association. See those events at: If you have an idea for something that alumni.uvm.edu should be covered in Vermont Medicine, 32 VERMONT MEDICINE pleasePhotographer email: [email protected] Name, Photographer Name Opposite: UVM Med Photo VOL 50, ISSUE 2 • 2013 33 HALL A | M.D. CLASS NOTES Development News HALL A

’77 Mark Novotny writes that he ’84 Jonathan Glass was among Kellie A. Sprague writes that she Joyce M. Dobbertin received the Annette R. Plante, Daughter of Class College of Medicine is “currently serving as CMO the physicians who performed “became the director of the Bone College of Medicine’s Service to of 1915 Alum, Funds Scholarship Marathon Team Raises for Cooley Dickinson Hospital in the  rst FDA-approved stem cell Marrow Transplant Program at Tufts Medicine & Community Award Northampton, Mass., as we join Mass. injection into a patient's cervical Medical Center in Boston in October at Reunion 2013. She is a family A diversity scholarship fund at the UVM College of Medicine, Funds for Steps to General Hospital. Still bene ting from spine for amyotrophic lateral 2012. Steve is still happy seeing kids physician at Corner Medical O ce established by Annette R. Plante in 2008, will receive an Wellness my UVM education and still hanging sclerosis treatment. The four-hour at Mass. General West.” at Northeastern Vermont Regional additional $198,000 thanks to a generous will provision she This year’s College of Medicine marathon out with Michael Polifka ’78.” operation included  ve cervical spine Hospital (NVRH) in St. Johnsbury, Ingrid Martinez-Andree writes: established. Annette, the daughter of College of Medicine alum team braved a cold and rainy day May 26 to Vt. In addition to being a dedicated John E. Alexander writes that injections containing a combined ’93 “At Children’s Primary Care and active member of her local Ulric R. Plante, Class of 1915, created the scholarship to honor her run the Vermont City Marathon in support of ’78 his daughter, Jane, was more than 500,000 stem cells. He Medical Group and Rady Children’s community, she has for the last father and her brother, Joseph Plante, a UVM alum from the Class cancer survivors who are participants in the married in September 2012. She is a neurologist at The Emory Clinic Hospital in San Diego, Calif. for almost several years served as Volunteer of 1955. The Dr. U.R. and Joseph Plante Endowed Scholarship Fund Steps to Wellness program. More than 70 currently is stationed at Fort Bragg, and professor of neurology at Emory 15 years. No more horseback riding or Medical Director for two weeks each N.C., with her Army husband. University in Atlanta. Glass is a volleyball though played all through supports medical students “with  nancial need who help advance people made up the team, which included 13 member of the American Academy residency and even as an attending. year at the Hillside Medical Clinic in the UVM College of Medicine’s goal of creating a diverse community.” full marathoners, 20 half marathoners, and John J. Ambrosino reports: “I moved of Neurology, American Neurological Lots and lots of gardening — roses Punta Gorda, Belize, and performed In her late 80s when she died in February of 2012, Annette Plante’s about 40 individuals running a leg on one of to Hermitage, Penn., and am still Association, and Society of and da odils! Still remember the similar volunteer work in Kingston working hard at vascular surgery — will provision ensures the scholarship fund will continue to help Ulric R. Plante, M.D.1915 the College’s relay teams. A total of 45 UVM Neuroscience. following from med school: Bruce and throughout Jamaica. hopefully to age 70!” generations of students achieve their goals. medical students, eight graduate students, Michele Gerin-Lajoie writes: Fonda playing hockey with Peter and Anne Gri th Hartigan writes: “Still The Plante family has a strong presence at the College: Annette also honored her father in 2007 10 faculty/sta members, one current Steps ’88 “I am well and practicing in Brad, and Bruce Fonda winning enjoying Michigan, close to family. through the naming of the Plante Student Lounge o the Given Courtyard. Thanks to her generosity, to Wellness patient, and several friends and 1980s Montreal, teaching residents and several intramural volleyball games Elizabeth, age eight, and Benjamin, doing lots of perinatal medicine. with Owen and Russell and Helain age  ve, keep us busy and laughing. students enjoy a space to study, relax and chat with classmates, cook a snack, or watch some family members participated on the team, REUNION 2014: 1984 + 1989 Love to climb big mountains all over. and Marcie, Mark DeMateo and Skippy I practice musculoskeletal medicine television. Dr. Plante practiced medicine for over 60 years; it is believed he delivered some 10,000 which collectively raised more than $24,000 singing "Get an A-I", Lobster Fest and at University of Michigan.” babies in rural northern New York over the course of his career. He cited his days at the College of to bene t Steps to Wellness, a medically Edward P. Havranek received Dinosaur cake! Being voted “Most Medicine as holding some of his fondest memories. ’83 a Distinguished Academic Jason Cook reports: “Settled based rehabilitation program for cancer Likely to Ride O into the Sunset” Achievement Award at the College 1990s ’99 down in Southern California, survivors. Class of 2016 medical students and Dr. Thanassi in biochem being of Medicine’s 2013 reunion. As a REUNION 2014: 1994 + 1999 working in the PICU of Children’s Sabrina Bedell, Tara Higgins, and James Levins the uno cial class photographer. professor of medicine at the Hospital of Orange County and playing IV served as co-leaders for this year’s team. Francis Nolan reports: “Now Snowball  ght during the  rst year University of Colorado School of at home with three lovely ladies Bequest Adds to Fund ’90 in Brisbane, Australia, working during a  re drill.” Fletcher Allen Health Care marathon teams Medicine and a cardiologist and (wife Sonia and daughters Isabella Honoring Harry Anton, EM for a few years. Awesome. See also raised money for Steps to Wellness. director of Health Services Research Stephen Vogt and his wife, and Roxana). Enjoy the beach days M.D. ’40 www.docdownunder.com for anyone at Denver Health Medical Center, ’96 Christine (UVM Class of 1990), in January but miss many things interested in life and EM Down Under. A generous bequest from Evelyn Anton, he has a long-standing interest in “live a well-balanced life in Hood about New England.” Thanks!” measuring and improving the River, Oregon.” When not working, who died at the age of 92 in July of 2011, quality of care for cardiovascular BJ Beck writes: “I continue to they enjoy time with their son Ripley, has added $200,000 to a fund established disease, particularly heart failure. ’91 see patients one day/week at age 4½, windsur ng, biking and 2000s in memory of her husband, Harry His current research focuses on Mass. General Hospital and to work working on their mini farm. REUNION 2014: 2004 + 2009 Anton, M.D. ’40. The endowed fund was causes and solutions to the problems in managed care, but starting this Holly Beeman Nath reports: established in 1987 by Evelyn and her son, of health disparities based on race summer, I am a full-time student at ’97 “I look forward to reconnecting Laura Trask reports: “Practicing Ray Anton, M.D., a member of the Class of and ethnicity. the Mass. College of Art & Design, ’00 endocrinology in Lewiston, with class of 1997 friends in 1970, to honor the elder Dr. Anton. A general working towards my BFA.” Maine. Our daughter, Mabel, just Ray Anton, M.D.’70, center, speaks with Marvin Neirenberg, Douglas W. Losordo received a September. Jackie Jeruss, Ana  nished kindergarten.” surgeon by training, Dr. Harry Anton also M.D.’60,left, and Shane Jacobson of the UVM Foundation, right, Distinguished Academic Achievement Domingues, Charlotte Ariyan, Jen served during his career as a general at Reunion 2012. Award at the College of Medicine’s Gilwee, Julie Smail, Wendy Hawks. Omar Khan received the practitioner in his community. Ray Anton, 2013 Reunion. An interventional Will gather to reminisce during ’03 College of Medicine’s Service to cardiologist and professor of a weekend get away with no Medicine & Community Award at an anesthesiologist, carried on the family’s spirit of involvement at the College; he is a past president of The College of Medicine 2013 Marathon Team medicine at the Northwestern kids, no patients and plenty Reunion 2013. Khan, who also holds the Medical Alumni Association and serves as a class agent. His parents, Evelyn and Harry, married in University Feinberg School of of laughs.” a master’s in health science from 1942; for many years she served as a nurse and o ce manager at his practice in Palmer, Mass. “ I had run VCM as a marathoner for ve years Medicine in Chicago, Ill., his major Halleh Akbarnia, an Johns Hopkins School of Public before and when I found out in January I’d Health, is medical director of research interests encompass ’98 attending emergency need surgery and then chemotherapy I was angiogenesis/vasculogenesis, physician at Presence Saint Preventive Medicine & Community progenitor/adult stem cells, Health and director of the Global Reunion Giving 2013 crushed to think I wouldn't be doing this Francis Hospital in Evanston, Ill., year’s marathon (this is how we runners tissue repair/regeneration, and received the Early Achievement Health Residency Track at Delaware’s vascular biology. Christiana Care Health System. The Celebration of Achievements during Medical think!). Steps to Wellness was that small Award at the College of Medicine’s Reunion May 31–June 2 honored the Class of 1963 Stephen Russell Payne has followed Reunion 2013. Prior to joining Nicole Piscatelli writes: “I shining star that allowed me the avenue to in their 50th anniversary year by introducing class up on the novel he published last Saint Francis Hospital, she was ’04 completed my surgical critical stay active but also, to my surprise, o ered year with a new non- ction work, assistant medical director at care training at Boston Medical Center members in attendance and presenting each individual this chance to be a part of the 25th VCM. Riding My Guitar: The Rick Norcross her residency program, Virginia and have relocated to Phoenix, Ariz. with a medal. The College also celebrated the generosity I am so very pleased to be o ered this Story. The new book chronicles the Commonwealth University where I am working as a trauma of alumni from all of the class years; they collectively chance and the program (in my third week) life of the noted folk singer and Medical Center-Virginia surgeon and surgical critical care Dean Rick Morin, left, accepts a check representing raised $740,781 to support student scholarship and has been amazing for me.” Green Mountain Chew-Chew Commonwealth University Health internist. If any alums are in the area medical education at their alma mater. John Murray, all alumni reunion giving during the Celebration — Brian Hard, founder. It’s available in bookstores System in Richmond, Va., and give me a call!” of Achievements at Reunion 2013. Presenting the M.D.’63 and Alan Walker, M.D.’63 presented Dean Rick Marathon Team member and throughout Vermont and via online was named “Teacher of the Year” check are Class of 1963 class agents Alan Walker, Morin a check at the ceremony on May 31. Steps to Wellness participant sources such as amazon.com. in 2005 by the residents there. M.D., center, and John Murray, M.D., right.

34 VERMONT MEDICINE PhotographerUVM Med Photo Name, Photographer Name VOL 50,49, ISSUE 2 • 20132012 35 HALL A | M.D. CLASS NOTES | Ph .D. CLASS NOTES HALL A | M.D. CLASS HALLNOTES A FLASHBACK 2013–2014 CONTINUING MEDICAL EDUCATION CONFERENCE SCHEDULE

Je ords Quality Care Bridging the Divide Symposium November 8, 2013 September 6, 2013 Hampton Inn Sheraton Hotel Colchester, Vt. Rich Parent reports: “I drove up Alyssa Wittenberg writes: Burlington, Vt. ’05 to the San Francisco Bay Area ’08 “I joined the faculty at USC after 25th Annual Eastern Winter to reunite with another UVM College of residency and I am busy opening a Primary Care Sports Dermatology Conference Medicine Medicine grad and close friend who new OB/GYN practice. I will be getting January 17–20, 2014 September 25–27, 2013 got married last November back in married this summer in Grafton, Topnotch Hotel Sheraton Hotel Vermont. We celebrated her wedding Vermont! My  ancé and I could not be Stowe, Vt. Burlington, Vt. on the West Coast at her sister’s more excited.” Emergency Medicine Update house in Menlo Park. The attendees Justin Stinnett-Donnelly, Imaging Seminar January 26–29, 2014 September 27–29, 2013 were: Rich Parent ’05 and wife Kelly ’10 a resident at Fletcher Allen Stowe Mountain Lodge Sheraton Hotel Parent; Gulnar Odera ’08; Michael Hart Health Care, led a group that gave Stowe, Vt. Burlington, Vt. ’12; Eleonore Werner ’12; Annie Coates a research presentation at the ’07 and new husband Tim Connolly; 23rd Annual Current Association of American Medical Breast Cancer Conference Concepts & Controversies Anne Kieryn ’06.” Colleges Integrating Quality: October 4, 2013 in Surgery ’06 Liz Lycett is “Still in Rochester, Improving Value and Educating Sheraton Hotel January 27–29, 2014 N.Y., and about to start my for Quality meeting in June in Burlington, Vt. Stowe Mountain Lodge chief residency, then likely a year at Rosemont, Ill. The group presented on Stowe, Vt. Critical Care Conference geriatrics. I’ll keep you posted when Fletcher Allen’s “Choosing Wisely” October 17–19, 2013 I hit the primary care market, likely campaign to reduce limited value Hospital Medicine 2014 The Essex in two years!” diagnostic testing. February 6–9, 2014 Essex Junction, Vt. Stowe ake Hotel & Spa Northern New England Stowe, Vt. Neurological Society 19th Annual Vermont Annual Meeting Perspectives in Anesthesia P h .D. NOTES access to treatment. Vaccines to October 25–26, 2013 March 5–9, 2014 cover the diversity of all HIV strains North Conway Grand Hotel Stowe Mountain Lodge Brian Foley writes: I work for have proven very di cult, but much North Conway, N.H. Stowe, Vt. ’95 the HIV Genetic Sequence progress is being made. ? Neurology for the That 70s Show and Immunology Databases at Los ’00 Malcolm Schinstine reports: Non-Neurologist FOR INFORMATION CONTACT: Alamos National Laboratory, primarily “Moved to Calgary, AB in October 25, 2013 Maybe it’s the sideburn-and-full-beard quotient, or the level of plaid, but this photo (whose label identi es its subjects as students in tracking the epidemiology and January — Department of Pathology North Conway Grand Hotel University of Vermont molecular evolution of HIV for aid in & Laboratory Medicine at University North Conway, N.H. Continuing Medical Education the Given Building Hall A) screams “1970s.” Bruce R. MacPherson, M.D.’67, now an associate professor emeritus, leads the class. Note vaccine design. I correspond with of Calgary. Welcome anyone who 128 Lakeside Avenue, Suite 100 the Kodak Carousel and Bell & Howell projectors by the rear wall. This shot was either “ opped” when originally printed, as the window- HIV/AIDS researchers all over the wants to visit— we are near Ban !” Burlington, VT 05401 world, and I have traveled to South (802) 656-2292 wall of Hall A was on the right of the seated audience, or it may actually have been taken in the slightly smaller Hall B. Hall A survived Joshua Farb is currently Africa, Switzerland, Portugal, The www.uvm.edu/medicine/cme ’06 working as a research and until renovations in the Given Building in 2012. Hall B was renovated into o ce space a few years earlier. Medical students today attend Netherlands, India, South Korea and development biochemist for AbbVie lectures in the Sullivan Classroom. Do you recognize yourself, or anyone else in this photo? Send in your IDs to [email protected] Serbia to teach HIV researchers how Biotech. He specializes in protein to characterize HIV strains they have and we will include them in a future issue of Vermont Medicine. puri cation and characterization for isolated from their patients. The early their antibody drug development years of my research, 1995 to CALLING ALL PH.D.S! pipeline. He is currently expanding 1997, were very depressing, reading his group by developing a new about the deaths of thousands of The Graduate Alumni committee of the UVM College of Medicine seeks antibody safety assay that will be The Flashback photo in the previous issue of Vermont Medicine (at left) brought in two quick and AIDS patients as the early drug more news from Ph.D. graduates of the College to share with their fellow used for all antibody drug candidates. de nitive responses from Class of 1954 members Edmund “Mickey” McMahon, M.D., Les Gaelen, monotherapies failed. But community members in the pages of Vermont Medicine. Send your Josh and Melissa Gove Farb (UVM combinations of drugs and especially news to medalumni.relations@ uvm.edu or call (802) 656-4014. and Michael Wiedman, M.D. They pointed out that the photo shows, left to right, 1954 classmates Department of Nutrition and Food the addition of the protease inhibitor George Economos, Wendell Smith, David Shea, Sarita Goodman, John Tampas, Les Gaelen, Sciences 2003) married in 2009 and No need to write another dissertation — just a brief catch-up for your class of drugs has resulted in near are expecting their  rst child in old friends and former faculty on where you are, and what you’re doing! Manfred Goldwein, Herbert Sillman, and Marvin Silk. normal lifespans for most HIV- August of this year. infected people today who have

36 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 37 ClassHALL A | M.D. Agent CLASS NOTES Directory HALL A | M.D. CLASS HALLNOTES A

Class agents are dedicated alumni who ’51 Edward W. Jenkins, 7460 South Pittsburg Ave., ’64 Anthony P. Belmont, 211 Youngs Point Road, ’01 Ladan Farhoomand, 7077 Heron Circle, Carlsbad, CA volunteer their time to serve as the voice of Tulsa, OK 74136 , (918) 492-7960, Wiscasset, ME 04578, (207) 882-6228, 92001, (760) 331-7151, [email protected] [email protected] [email protected] Joel W. Keenan, Greenwich Hospital, Five Perryridge their classmates at the College of Medicine, Road, Greenwich, CT 06830, [email protected] and who work to encourage support of ’52 Arthur Kunin, 226 Windmill Bay Road, Shelburne, VT ’65 George A. Little, 97 Quechee Road, Hartland, VT JoAn Louise Monaco, 1034 Fifth Avenue, New York, the College each year. Agents help deliver 05482, (802) 985-5410, [email protected] 05048, (802) 436-2138, NY 10028, (212) 988-7788, [email protected] Arthur Perelman, 165 Woodland Ave., Summit, NJ [email protected] information to their far- ung friends about 07901, (908) 277-6454, [email protected] Joseph H. Vargas III, 574 US Route 4 East, Rutland, ’02 Jonathan Vinh Mai, 504 Ga ney Road, the ongoing work of the College, and at VT 05701, (802) 775-4671, [email protected] Bristol, TN 37620, (570) 275-4681, the same time help their medical alma ’53 Please email [email protected] [email protected] if you’d like to serve as 1953 class agent. ’66 Robert George Sellig, 31 Overlook Drive, Kerry Lee Landry, (919) 732-9876, mater keep abreast of the news and views Queensbury, NY 12804, (518) 793-7914, John E. Mazuzan, Jr., 366 South Cove Road, [email protected] of their class. If you would like to learn ’54 [email protected] Burlington, VT 05401, (802) 864-5039, Mary O’Leary Ready, [email protected] G. Millard Simmons, 650 Mystic Point Drive, more about serving as a class agent, [email protected] Maureen C. Sarle, [email protected] contact Cristin Gildea at (802) 656-4014 Sun City Hilton Head, Blu ton, SC 29909, Omar Khan, 33 Clearwater Circle, Shelburne, VT or [email protected]. ’55 Richard Bailey, 2100 Lambiance Circle, Apt 201, (843) 705-2264, [email protected] ’03 Naples, FL 34108, [email protected] 05482, (802) 985-1131, [email protected] ’67 John F. Dick II, P.O. Box 60, Salisbury, VT 05769, Scott Goodrich, 309 Barben Avenue, Watertown, NY Ira H. Gessner, 1306 Northwest 31st Street, (802) 352-6625 Francis Arnold Caccavo, 51 Thibault Parkway, ’56 13601, [email protected] ’43 Gainesville, FL 32605, (352) 378-1820, Burlington, VT 05401, (802) 862-3841, David Jay Keller, 262 Maplewood Common, [email protected] .edu ’68 Jillian S. Sullivan, [email protected] [email protected] Class agent Rebecca Brakeley, M.D.’09 ’04 Moretown, VT 05660, (802) 496-2623, Steven D. Lefebvre, [email protected] Carleton R. Haines, 88 Mountain View Road, ’57 Larry Coletti, 34 Gulliver Circle, Norwich, CT 06360, [email protected] Williston, VT 05495, (802) 878-3115 (860) 887-1450 Timothy John Terrien, 14 Deer eld Road, South ’05 Julie A. Alosi, [email protected] Burlington, VT 05403, (802) 862-8395 ’79 Sarah Ann McCarty, [email protected] ’89 Peter M. Nalin, 13216 Gri n Run, Carmel, IN 46033, Richard J. Parent, [email protected] Wilton W. Covey, 357 Weybridge Street, ’44 ’58 Peter Ames Goodhue, Stamford Gynecology, P.C., Todd Gladstone, [email protected] Dennis Plante, [email protected] (317) 962-6656, [email protected] Middlebury, VT 05753, (802) 388-1555 70 Mill River Street, Stamford, CT 06902, (203) ’06 William C. Eward, 101 Wood Valley Corner, Durham, Richard Nicholas Hubbell, 80 Summit Street, Barbara Angelika Dill, 120 Hazel Court, Norwood, NJ 359-3340 Susan Pitman Lowenthal, 200 Kennedy Drive, ’80 ’90 NC 27713, [email protected] Robert E. O’Brien, 414 Thayer Beach Road, ’69 ’45 Torrington, CT 06790, (860) 597-8996, Burlington, VT 05401, (802) 862-5551, 07648, (201) 767-7778, [email protected] Deborah Rabinowitz Abrams, Colchester, VT 05446, (802) 862-0394, Jay E. Selcow, 27 Reservoir Road, Bloom eld, CT [email protected] ’59 susan_w_pitmanlowenthal@p zer.com John Dewey, 15 Eagle Street, Cooperstown, NY 2777 Noll Valley Loop NE, Poulsbo, WA 98370, [email protected] 06002, (860) 243-1359, [email protected] ’91 Bruce Leavitt, 312 Four Sisters Road, South 13326, [email protected] [email protected] H. Gordon Page, 9 East Terrace, South Burlington, VT ’70 Raymond Joseph Anton, 1521 General Knox Road, ’81 05403, (802) 864-7086 ’60 Marvin A. Nierenberg, 15 West 81st Street, Russell, MA 01071, (413) 568-8659, Burlington, VT 05403, [email protected] Allison Collen, [email protected] ’92 Mark Eliot Pasanen, 1234 Spear Street, South ’07 New York, NY 10024, (212) 874-6484, [email protected] Betsy Sussman, 325 Dorset Heights, South Scot Millay, [email protected] Please email [email protected] Burlington, VT 05403, (802) 865-3281, ’46 [email protected] John F. Beamis, Jr., 1296 Kapiolani, Apt. 1605, Burlington, VT 05403, [email protected] Anne Coates, [email protected] if you’d like to serve as 1946 class agent. [email protected] Melvyn H. Wolk, Clinton Street, P.O. Box 772, Honolulu, HI 96814, [email protected] Louis Polish, 11 Vale Drive, South Burlington, VT Waverly, PA 18471, (570) 563-2215, Mark Hunter, 21 Lindenwood Drive, South Edward Crane, MD ’47, P.O. Box 1799, 05403, [email protected] ’93 Joanne Taplin Romeyn, 22 Patterson Lane, Durham, ’08 ’47 [email protected] Wayne E. Pasanen, 117 Osgood Street, CT 06422, (860) 349-6941, [email protected] Burlington, VT 05403, [email protected] Frisco, CO, 80443 ’71 Diane Rippa, [email protected] North Andover, MA 01845, (978) 681-9393, ’82 Brad Watson, [email protected] Alyssa Wittenberg, 1800 N. Normandie Ave. Wilfred L. Fortin, 17 Chapman Street, Nashua, NH S. James Baum, 1790 Fair eld Beach Road, Fair eld, ’61 [email protected] #303, Los Angeles, CA 90027, ’48 03060, (603) 882-6202, [email protected] Holliday Kane Ray eld, P.O. Box 819, Waits eld, VT CT 06430, (203) 255-1013, [email protected] Edwin G. Singsen, 439 Indian Avenue, Portsmouth, ’83 Diane M. Georgeson, 2 Ravine Parkway, ’94 [email protected] 05673, (802) 496-5667, ray [email protected] Ruth Andrea Seeler, 2431 North Orchard, Chicago, IL RI 02871, (401) 849-6482, [email protected] Oneonta, NY 13820, (607) 433-1620, Ashley Zucker, 2209 Albany Street, ’49 Joseph C. Foley, 32 Fairmount Street, Burlington, VT ’62 60614, (773) 472-3432, [email protected] [email protected] Allyson Miller Bolduc, 252 Autumn Hill Road, Durham, NC 27705, [email protected] 05401, (802) 862-0040, [email protected] ’72 F. Farrell Collins, Jr., 205 Page Road, Pinehurst, NC Anne Marie Massucco, 15 Cedar Ledge Road, ’95 28374, (910) 295-2429 South Burlington, VT 05403, (802) 863-4902, Rebecca Brakeley, [email protected] Edward S. Sherwood, 24 Worthley Road, Topsham, ’63 John J. Murray, P.O. Box 607, Colchester, VT 05446, West Hartford, CT 06107, (860) 521-6120, ’09 [email protected] Kate Murray Mitchell, [email protected] VT 05076, (802) 439-5816, [email protected] (802) 865-9390, [email protected] [email protected] ’73 James M. Betts, 715 Harbor Road, Alameda, CA H. Alan Walker, 229 Champlain Drive, Plattsburgh, NY Anne Marie Valente, 66 Winchester St., Campbell Stewart, [email protected] ’50 Simon Dorfman, 8256 Nice Way, Sarasota, FL 94502, (510) 523-1920, [email protected] Richard C. Shumway, 34 Coventry Lane, Avon, CT ’96 12901, (518) 561-8991, [email protected] ’84 Apt. 503, Brookline, MA 02446, Michael Alavian, [email protected] 34238, (941) 926-8126 Philip L. Cohen, 483 Lakewood Drive, Winter Park, 06001, (860) 673-6629, [email protected] ’10 FL 32789, (407) 628-0221, [email protected] [email protected] Pei Chen, [email protected] Patricia Ann King, 832 South Prospect Street, Suzy Parker, [email protected] ’85 Vito Imbasciani, [email protected] Heidi Schumacher, [email protected] Suzy Frisch, [email protected] Burlington, VT 05401, (802) 862-7705, ’74 Douglas M. Eddy, 5 Tanbark Road, Windham, NH [email protected] ’11 Carrie Moats, [email protected] 03087, (603) 434-2164, [email protected] ’86 Darrell Edward White, 29123 Lincoln Road, Bay Nicholas Aunchman, Cajsa Schumacher, 78 Euclid Avenue, Albany, NY Village, OH 44140, (440) 892-4681, ’97 Julie Smail, 390 Bridge St., South Hamilton, MA [email protected] 12203, [email protected] [email protected] 01982, (978) 468-1943 , [email protected] ’12 Melissa Marotta Houser, Halleh Akbarnia, 2011 Prairie Street, Glenview, IL ’75 Ellen Andrews, 195 Midland Road, Pinehurst, NC ’87 J. Michael Jaeger, Grove Road, Charlottesville, VA ’98 [email protected] 28374, (910) 295-6464, [email protected] 22901, [email protected] 60025, (847) 998-0507, [email protected] Auna Leatham, [email protected] Je rey Rosenblatt, 11 McQuillans Hill Drive, Everett Jonathan Lamm, 11 Autumn Lane, Meghan Beucher, [email protected] ’76 Don P. Chan, Cardiac Associates of New Hampshire, ’99 Gorham, ME 04038, je [email protected] Stratham, NH 03885, (603) 580-2666, Martha Choate Monson, Suite 103, 246 Pleasant Street, Concord, NH 03301, Helene Goldsman, 105 Pamunkey Turn, [email protected] (603) 224-6070, [email protected] [email protected] Yorktown, VA 23693, [email protected] Deanne Dixon Haag, 4215 Pond Road, Sheldon, VT ’13 Shetal Patel, [email protected] James C. Hebert, 583 Stockbridge Road, Charlotte, 05483, (802) 524-7528 ’77 ’88 H. James Wallace III, 416 Martel Lane, Idil Aktan, [email protected] VT 05445, [email protected] St. George, VT 05495, (802) 872-8533, Lizzie Anson, [email protected] Mark A. Popovsky, 22 Nauset Road, ’00 Jay Edmond Allard, USNH Yokosuka, PSC 475 Box [email protected] 1757, FPO, AP 96350, [email protected] Sharon, MA 02067, (781) 784-8824, Lawrence I. Wolk, 5724 South Nome Street, [email protected] Michael Jim Lee, 71 Essex Lane, Irvine, CA 92620, Greenwood Village, CO 80111, (303) 771-1289, [email protected] [email protected] ’78 Paul McLane Costello, Essex Pediatrics, Ltd., Naomi R. Leeds, 305 Third St. #204, Cambridge, MA Class agents Jay Selcow, M.D.’59 and James Hebert, M.D.’77. 89 Main Street, Essex Junction, VT 05452, (802) 02142, [email protected] 879-6556, [email protected]

38 VERMONT MEDICINE UVM Med Photo Photographer Name, Photographer Name VOL 50, ISSUE 2 • 2013 39 CLASS REUNIONS

’58 55  R eunion

View Highlights of the celebration of Achievements ’63 that formally opened Reunion 2013. Go to: uvm.edu/medicine/vtmedicine 50  R eunion

’83 30  R eunion

REUNION 2013 ’88 25  R

REUNITED! eunion Alumni of the College of Medicine traveled far and wide to attend Reunion 2013, May 31 to June 2. All told, the attendees represented 25 states plus Canada. Alumni came from as far away as Hawaii, Washington, California, New Mexico, Colorado, and Minnesota to reconnect with their classmates and former teachers, and visit familiar and new areas of the campus. The oldest class ’98 represented was the Class of 1948, with two members attending, and the youngest alumni were

from the Class of 2003. Over 30 current medical students took part in reunion this year, mingling 15  R with and meeting their predecessors on tours and over meals.

If you’re in a class that ends in 4 or 9, mark your calendar for eunion REUNION 2014: JUNE 6–8, 2014!

40 VERMONT MEDICINE VOL 50,49, ISSUE 2 • 20132012 41 Obituaries HALL A | OBITUARIES

’42 Frank E. Harrigan Jr., M.D. and medical degrees from the 1987 to 1989 he was president of the UVM College of Medicine, and Dr. Harrigan died May University of Vermont, and served the Rhode Island Hospital Medical practiced as a medical doctor in 8, 2013. He was 93. Born in for two years with the Army,  rst Sta Association. He also authored Miami Beach, Fla., for many years. Lewiston, Maine, on April 13, as a General Medical O cer and many peer- reviewed scienti c He spent his retirement years in the 1917, he grew up in West Hartford, then as the neurologist at the 5th papers. Dr. Hanson’s professional Berkshires of Massachusetts. Conn. He earned his undergraduate General Hospital in Stuttgart, a liations included the Eastern and medical degrees from the Germany. After returning to the Radiological Society, the European University of Vermont, and was a United States and completing Pediatric Radiology Society and FACULTY member of UVM’s  rst ski team. a residency in pathology at the Radiological Society of North While at UVM, he obtained his Massachusetts General Hospital America. Jim served on numerous Burton E. Sobel, M.D. private pilot’s license, beginning (MGH), and a fellowship in boards, including those of St. Dr. Sobel died at his home in an avocation that lasted the rest neuropathology at MGH and Andrew’s School, Emma Pendleton Colchester, Vt., on May 3, 2013. of his life. From 1942 to 1943, Harvard Medical School, Dr. Bradley School, Rhode Island He received his M.D. at Harvard, Dr. Harrigan was an intern at Collins joined the pathology faculty Magnetic Imaging and Rhode graduating magna cum laude in Walter Reed Army Hospital in at the University of Florida Medical Island Hospital. He was a resident 1962. He completed his internship Washington. D.C. prior to overseas School. During his tenure there of Barrington, R.I. from 1966 to and residency training at the Peter combat duty as a medical o cer he established a new section of 2012. Bent Brigham Hospital in Boston, in the 5th AAF in the Southwest neuropathology and created a fully and his fellowship training at the Paci c through the end of World equipped laboratory of electron ’59 Howard Randall “Randy” National Heart, Lung, and Blood War II. He was brie y stationed microscopy. He was also awarded Deming, M.D. Institute, followed by academic and in Japan following the end of the Distinguished Professor Award Dr. Deming died May 5, 2013. administrative leadership positions con ict. In 1947, Dr. Harrigan for his teaching contributions. Born in St. Albans, Vt., on April at the University of California, resigned his commission with the After 11 years, Dr. Collins left 8, 1932, he attended Bellows Free San Diego, Washington University rank of major to pursue a career as Florida and accepted a position as Academy in St. Albans and later and Barnes Hospital in Saint a civilian physician. He moved to professor of pathology at Upstate entered the Hotchkiss School in Louis (Director, Cardiovascular Manchester in 1948 and established Medical Center in Syracuse, Lakeville, Conn., as a post-graduate Division). In 1994, Dr. Sobel a private medical practice that he N.Y., where he remained until his scholarship student. He graduated began serving as Chair of the Burton E. Sobel, M.D., in 2009. continued for the next forty years. retirement in 1996. Dr. Collins from Dartmouth College in Department of Medicine and the He enthusiastically embraced was a member of four NIH study Hanover, N.H., in 1955, before E.L. Amidon Professor of Medicine the challenges of rural medicine, sections, served on the editorial earning his medical degree from the at the UVM College of Medicine. and quietly gained the reputation board of a neuropathology journal, College of Medicine. He completed His vision and energy revitalized including a Research Career Medicine. Dr. Caldwell completed program in 2008. He practiced he practiced until his retirement in from his peers as one of the best and published nearly 100 scienti c internship and residency training the Department of Medicine, Development Award from the internal medicine training at the locum tenens adult, child and 1997. He was on the medical sta diagnosticians in northern New articles related to brain structure in radiology at the University expanding its research endeavors, National Institutes of Health and Mary Fletcher Hospital. He was adolescent psychiatry in Maine and at Maine Medical Center and the England. During the 1950s and and pathology and to spinal cord Hospital in Burlington and the education programs and clinics. a Distinguished Scientist Award a member of the United States Massachusetts and most recently Mercy Hospital for thirty years. into the 1970s he was the principal injury. In retirement he was actively Boston Children’s Hospital in During his tenure as chair, Dr. from the American College of Public Health Service serving at at the Family Services Inc., in While at Maine Medical Center, provider of care for ski injuries involved in a study of the pathology Boston, Mass. He then entered the Sobel created the Cardiovascular Cardiology, and was a leader in the National Institutes of Health Lawrence, Mass. he was Director of the Division of from Bromley and Snow Valley. of consciousness. U.S. Navy as attending radiologist Research Institute at the UVM subspecialty societies including the from 1963 through 1966, following Internal Medicine from1983–1993 He was also an FAA certi ed at the U.S. Naval Hospital in and Fletcher Allen Health Care to American College of Cardiology, which he returned to the University ’60 Philip G. Whitney, M.D. and Medical Director of Nutrition Aviation Medical Examiner, and ’58 Daniel James “Jim” Hanson, Jacksonville, Fla., where he enhance the research mission of the American Heart Association, of Vermont as an assistant professor Dr. Whitney died at home Support Services 1987–1997. He helped found the Regional Medical M.D. practiced for two years under the both institutions, and in 2005 left and the Society for Experimental of medicine, Department of in Scarborough, Maine, on May was active in teaching medical Examiner system for Vermont, in Dr. Hanson died March 25, 2013, Berry Plan. Upon completion of his his position as Chair to become Biology and Medicine. He had Medicine, College of Medicine in 29, 2013 from pancreatic cancer. interns and residents at Maine which he served throughout most at Tampa General Hospital. Born tour, he joined the Maine Medical the institute’s  rst director. He more than 800 manuscripts the cardiology division, having been He was 79. He grew up in West Medical Center during his entire of his career. He was an active sta June 18, 1929, in St. Clair, Mich., Center Department of Radiology continued to serve as a professor published, and edited major selected as a career development Lebanon, N.H. He attended career, receiving Maine Medical member of the Putnam Memorial he grew up in Calais, Maine. He in the summer of 1965. During of medicine and biochemistry, cardiovascular and medical awardee of the NIH. He left the both college and medical school Center’s Teacher of the Year in 1971 Hospital in Bennington from 1948 received a Bachelor of Science his thirty years of active practice at earning the E.L. Amidon Award scienti c journals. College of Medicine in 1971 to at the University of Vermont. and 1976. He served as Assistant to 1982, and an honorary member degree from Muhlenberg College Maine Medical, he taught residents, for Teaching Excellence in 2007, ere will be a celebration of the become the director of pulmonary After graduating with his M.D., Professor of Clinical Medicine at after that. At the time of his passing in 1950, and served for three years served on multiple committees and and being named a University of life of Dr. Sobel at the Ira Allen medicine and respiratory medicine he completed his internship at Tufts University School of Medicine he was the oldest licensed physician as a captain in the United States chaired the department from 1984 Vermont Distinguished University Chapel on the UVM campus on at the Maine Medical Center Strong Memorial Hospital in 1970 to1982 and associate in the state of Vermont. He served Army. From 1962 to 1965, he was to 1987. He was a member of the Professor in 2009. Dr. Sobel October 11 at 10 a.m. (MMC) in Portland, Maine, until Rochester, N.Y., and his internal professor of clinical medicine at as medical o cer for the Vermont a faculty member in the radiology American Medical Association, was internationally recognized 1982. At MMC he was a member medicine residency at University the College from 1982 to 1997. Wing of the Civil Air Patrol for department at the University Radiological Society of North as a leader in cardiovascular Edgar J. Caldwell III, M.D. of the Pediatric Cystic Fibrosis of Washington Hospital in Seattle, ’58 Team from 1971 through 2002 Washington. He served as Captain over twenty years at the rank of of Kentucky Hospital. He then America, American College of medicine. He pioneered ground- Dr. Caldwell died on We note with sadness the passing and was director and founder of in the US Army at the 21st lieutenant colonel. served as a radiologist at Roger Radiology, and Maine Medical breaking research in cardiology November 25, 2012. He was 79 on July 12, 2013 of Doreen Freeman the Adult Cystic Fibrosis Clinic. Evacuation Hospital in Augsburg, Williams Hospital and Rhode Association. that had a major impact on how years old. He lived most recently who, along with her late husband, George H. Collins, M.D. Dr. Caldwell’s desire to continue Germany, from 1964 to 1966. Dr. Island Hospital in Providence while heart attack patients are treated, in Bolton, Mass. He graduated Houghton, was one of the strongest ’53 to care for those with cystic Whitney began private practice in Dr. Collins died February 23, also holding a faculty position Lawrence Schine, M.D. including extensive research on from Pinkerton Academy in 1950 supporters of the College and of ’60  brosis led him to complete the the Biddeford/Saco area of Maine 2013, at his home in Skaneateles, at Brown University. From 1981 Dr. Schine died April 21, the dissolution of blood clots and and graduated from the University medical education in Vermont. MMC adult psychiatry residency in 1966 and the following year N.Y., after a short illness. He was until his retirement in 1994, Dr. 2013, in Florida. He was 78. Born heart disease in patients with type of New Hampshire in 1954, An appreciation the Freemans program in 2003 and the child joined the Vaughan Street Internal born in Albany, N.Y., in 1927. Hanson was Rhode Island Hospital in 1934 in Connecticut, he was a 2 diabetes. He was the recipient before coming to the College of will appear in the next issue of He earned his undergraduate Radiologist-in-Chief, and from graduate of Harvard University and of numerous prestigious awards and adolescent psychiatry training Medical practice in Portland, where Vermont Medicine.

42 VERMONT MEDICINE VOL 50, ISSUE 2 • 2013 43 June 22, 2013 11:52 a.m. Arthur J. Perelman, M.D.’52 (center) and his sons Robert, left, and Jon, right, listen to speakers commemorating the establishment by the Perelman family and friends of a $1 million endowment at the Vermont Cancer Center to fund the Charlotte E. Perelman Cancer Research Fund, named in memory of Dr. Perelman’s late wife. photograph by Je Clarke Non-Pro t Org. U.S. POSTAGE PAID Burlington VT Permit No. 143

VERMONT MEDICINE 89 Beaumont Ave. Burlington VT 05405

Reconnect with faculty. Revisit the your medical career place where began. Recall the good times. Renew old friendships. old Renew good times. the Recall

JUNE 6–8 2014

ATTENTION CLASSES OF 1944, ’49, ’54, ’59, ’64, ’69, ’74, ’79, ’84, ’89, ’94, ’99, ’04 & ’09!

The UVM Medical Alumni Association invites you and your family to plan now to join your classmates for Reunion 2014 — June 6–8, 2014. Come back to Burlington and the UVM campus, your home during medical school. You may have lost contact with your classmates and former teachers, but Reunion will give you the chance to reconnect, rekindle old friendships, check out favorite places, talk with faculty, meet the medical students of today, and experience rst-hand the growth and evolution For more information, contact the UVM Medical Development & Alumni of your medical alma mater. Relations O ce at (802) 656-4014 or [email protected]

EVENTS INCLUDE: Medical Education Today Session • Tours of the College, including the Clinical Simulation Laboratory Alumni Awards and Reception • Medical Alumni Picnic • Nostalgia Hour • Class Receptions

WWW.UVM.EDU/MEDICINE/ALUMNI