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Rabbit Anti-NBPF3 antibody

SL19035R

Product Name: NBPF3 Chinese Name: NBPF3蛋白抗体 AE2; NBPF3; NBPF3_HUMAN; Neuroblastoma breakpoint family member 3; Protein Alias: AE2; Protein SHIIIa4; RP11-293F5.5. Organism Species: Rabbit Clonality: Polyclonal React Species: , ELISA=1:500-1000IHC-P=1:400-800IHC-F=1:400-800ICC=1:100-500IF=1:100- 500(Paraffin sections need antigen repair) Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 73kDa Cellular localization: cytoplasmic Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human NBPF3:401-500/633 Lsotype: IgGwww.sunlongbiotech.com Purification: affinity purified by Protein A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed: PubMed This is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated primarily located in segmental duplications on human 1. This gene family has experienced its greatest expansion within Product Detail: the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. DUF1220 copy number variations in human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Feb 2013]

Subcellular Location: Cytoplasm.

Tissue Specificity: Expressed in testis and fetal heart, as well as in non small cell lung carcinoma and neuroblastoma cell line.

Similarity: Belongs to the NBPF family. Contains 5 NBPF domains.

SWISS: Q9H094

Gene ID: 84224

Database links:

Entrez Gene: 84224 Human

SwissProt: Q9H094 Human

Unigene: 325422 Human www.sunlongbiotech.com Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.