Product Data Sheet PE anti-human CD143 (Angiotensin-converting )

Catalog # / Size: 2321020 / 100 tests Clone: 5-369 Isotype: Mouse IgG1, κ Reactivity: Human Preparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody. Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). Concentration: Lot-specific GM-CSF-stimulated human monocytes (day-3) stained with the 5-369 PE (gated in CD14+ cell population)

Applications:

Applications: Flow Cytometry Recommended Each lot of this antibody is quality control tested by immunofluorescent staining Usage: with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Description: CD143 (ACE, kininase II, peptidyl 1, peptidase P, carboxycathepsin) is a 171 kD, type I, single chain transmembranal metallopeptidase, whose is zinc. Its main targets are angiotensin I and bradykinin, acting as a blood pressure regulator. CD143 is expressed in endothelial cells; varying amounts of CD143 have been reported in different epithelial cells. The activation of macrophages and histiocytes induces the expression of this molecule. Antigen 1. Nakamura T, et al. 2009. Int Heart J. 50:501. References: 2. Jayasooriya AP, et al. 2008. P. Natl. Acad. Sci. USA 105:6531. 3. Jokubaitis VJ, et al. 2008. Blood 111:4055. 4. Arndt PG, et a

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