TRIM21 Rabbit Polyclonal Antibody – TA327221 | Origene

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA327221

TRIM21 Rabbit Polyclonal Antibody Product data:

Product Type: Primary Antibodies Applications: IF, IHC, WB Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:200;IF 1:10 - 1:100 Reactivity: Human, Mouse, Rat Host: Rabbit Isotype: IgG Clonality: Polyclonal Immunogen: Recombinant protein of human TRIM21 Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 Concentration: lot specific Purification: Affinity purification Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Predicted Protein Size: 54 kDa Gene Name: tripartite motif containing 21 Database Link: NP_003132 Entrez Gene 20821 MouseEntrez Gene 308901 RatEntrez Gene 6737 Human P19474 Background: TRIM21 has multiple N-terminal zinc finger motifs(has E3 ligase activity), a central leucine zipper, and a potential N-glycosylation site. TRIM3 is a E3 ubiquitin-protein ligase. It can form a ubiquitin ligase complex with E2 UBE2D2, which function not only for the uniquitination of USP4 and IKBKB but also for its self-ubiquitination. It has a role in the regulation of the cell cycle progression and could enhance the decapping activity of DCP2. It can exist in all mammalian cells as a ribonucleoprotein particle , which composed of a single polypeptide and 1 of 4 small RNA molecules. Synonyms: RNF81; Ro; RO52; SSA; SSA1

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 3 TRIM21 Rabbit Polyclonal Antibody – TA327221

Protein Families: Druggable Genome

Protein Pathways: Systemic lupus erythematosus

Product images:

Western blot analysis of extracts of various cell lines, using TRIM21 antibody.

Immunohistochemistry of paraffin-embedded mouse heart using TRIM21 antibody at dilution of 1:100 (x40 lens).

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 3 TRIM21 Rabbit Polyclonal Antibody – TA327221

Immunofluorescence analysis of U2OS cell using TRIM21 antibody. Blue: DAPI for nuclear staining.