Spring 2013 number 37

Making Research Relevant & Ready The Donaghue Foundation Newsletter: Focused on research and knowledge uptake initiatives.

Inside This Issue

Page 3 Women’s Health Celebrates

Page 4 R3 Grant Awards

Page 6 Behavorial Economics Research New grant program for 2013 Another Look: Better Health for Elders Page 3 in Care Facilities Donaghue Q&A Page 6 Sometimes a good data set needs another look. that there are relevant datasets. So Donaghue is using its new grant program to This program is open to investigators in New Donaghue-AAMC Grant get additional research knowledge out of existing England and New York. In 2013, the Foundation Page 7 data sets. will invest approximately $450,000 in this grant This new grant program, which reaffirms program. Our goal is to award up to four two- Beyond Eureka! 2013 Donaghue’s support for research that has the year projects. Grantees may use this award to near term potential to improve health, will augment funding for a project already funded provide funding for medical and health-related through another grant. Practically Speaking is published three times a research projects that can improve the quality The application process will have two phases. year by the Donaghue Foundation to commu- of care and the quality of life for the elderly Phase 1 is a letter of intent that is due by May 10, nicate its grantmaking and knowledge uptake population in nursing homes or other care 2013. In Phase 2, some of the applicants will be activities. Readers are welcome to contact the facilities. Specifically, this program invites invited to submit a full application. Donaghue Foundation office for more information about researchers interested in addressing a particular will be using a new review method for its letters the work of the Donaghue Foundation by calling problem affecting the elderly population in care of intent phase; all letters will be reviewed 860.521.9011 or by sending an email. facilities to analyze data that already exist to solely for the quality of the research idea that address their research question. New data is proposed, and information about applicants President and Trustee: Lynne L. Garner, PhD collection will not be allowed in this program. and their institutions will not be a part of this [email protected] Researchers applying for this grant must evaluation. Full applications will be reviewed identify a stakeholder in the care delivery or by the entire science review committee, and Vice President: Nancy C. Yedlin, MPH policy arena with whom they will either consult committee members will have access to all [email protected] or collaborate and who is willing to work with information from the application, including Grants Administrator: Stacy Cloud the researcher to develop a research product the applicant’s qualifications and his or her [email protected] that may be readily used to improve care or institution. quality of life. In order to receive the award, the Administrative Assistant: Wendy Vachon applicant must demonstrate how their research For more information about the Another Look [email protected] question is important to the stakeholder and grant program, go to www.donaghue.org.

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Letter from the Trustees

n addition to planning for new grant programs, the Donaghue office is busy getting ready for the May 3 Beyond Eureka! conference. We believe this year’s topic about science is critically important, Iand we’re confident that our speakers will provide you with a morning filled with important insights. Our excitement is growing as we look forward to this event. But we also have to admit to a slight feeling of nostalgia as we face doing our last Beyond Eureka! — at least, the last one for the foreseeable future. We’ve given a lot of thought to the question of when is the best time to put the series on hold, and it wasn’t an easy decision for us to make. But now that we’ve gone through the process of weighing the pros and cons and discussing it with our Lynne Garner, PhD, President and Trustee advisers, we’re confident that it’s the right time to make this decision. and Amy R. Lynch, JD, U.S. Trust, Bank of America, Trustee There’s isn’t any one specific reason why we decided not to continue Beyond Eureka!, but here is a major factor: it’s a big effort and Donaghue is a small foundation. Each year, the Donaghue staff starts working on developing themes and scouting speakers soon after the dust has settled from the previous one. Then for the next twelve months, it’s a staple on the office meeting agendas. This means, of course, that the time we spend on planning and executing a conference cannot be spent on other activities. Yet Ethel Donaghue gave us an exciting and expansive purpose that requires us to always think creatively about the best ways to achieve our mission. We look forward to having this “open space” to do just that. In the meantime, we still have those final planning details to attend to, and we look forward to seeing you at Beyond Eureka! on May 3.

Amy R. Lynch, JD Lynne Garner, PhD U.S. Trust, Bank of America, Trustee President and Trustee

Donaghue Foundation BeyondEureka! Conferences

2012 BeyondEureka! Evaluating risk — 2009 BeyondEureka! Innovation in the 2007 BeyondEureka! Closing the gap How perception shapes our health quest for better health: Patient-driven between health research & use: New Speakers: transformations in research, technology approaches from philanthropy, business David Ropeik and treatments and healthcare Author & consultant, Ropeik and Associates Speakers: Speakers: Brian Zikmund‐Fisher, PhD Alejandro (Alex) Jadad, MD, DPhil Scott Johnson Assistant Professor, University of Michigan Chief Innovator & Founder, Centre for Global Founder & President, Myelin Repair Foundation eHealth Innovation Michael Mustille, MD 2011 BeyondEureka! Design thinking — Sharon F. Terry, MA Associate Executive Director for External Affairs, Design thinking for health: Better President & CEO, Genetic Alliance Kaiser Permanente information, experience & outcomes Ben Heywood Dale Whitney Speakers: Co-Founder & President, PatientsLikeMe Vice Chair Leapfrog Group, Past President, Jeneanne Rae Bridges to Excellence Founder, Motiv Strategies 2008 BeyondEureka! Turning what we Camille Kubie know into what we do. Reflections, success 2006 Beyond Eureka! Discovery to action Manager, Global Brand & Design, GE stories and cautionary tales How can we bridge the gap between sci‐ Ben Fry Speakers: ence and the public’s health? Principal, Fathom Atul Gawande, MD, MPH Speakers: Surgeon, author Diane Meier, MD 2010 BeyondEureka! Why is getting healthy Harlan Krumholz, MD, SM Founder, Center to Advance Palliative Care so hard? And what we can do about it. Professor of Medicine, Yale University Alan Andreasen, PhD Behavioral and cultural perspectives Elizabeth Pivonka, PhD, RD Professor of Marketing, Georgetown University Speakers: President and CEO, Paul Raeburn Dan Ariely, PhD Produce for Better Health Foundation Science journalist Behavioral Economist, Duke University and MIT, Veronica Nieva, PhD Author of Predictably Irrational Vice President, Westat Val Curtis, PhD Health Anthropologist, London School of Hygiene and Tropical Medicine

2 Spring 2013 Practically Speaking The Patrick and Catherine Weldon Donaghue Medical Research Foundation

Donaghue & to answer the research be reviewed. Therefore, as we began to design Q It’s always good to see questions related to that initial this program we knew that we wanted to have a new grant program from Donaghue, Agrant, but many other important studies can a more tightly drawn topic area. We also knew but this one has me puzzled.Q Why is it also be supported by these data. Too often, that we wanted it to be in an area of patient only open to researchers using an existing data however, the requirements to begin collecting care that could have near-term impact. Our early source? Why only for research on nursing homes? data for the next research project can get in the discussions with advisers and colleagues And why are you going outside Connecticut for this? way of conducting those additional studies. In reinforced our idea that patient care for elders our small way, we’re encouraging researchers to in group facilities was an area that had sufficient A These are three good questions about our add to the value of these public or privately-held data sources to support research and that new “Another Look: Better Health for Elders in databases by using them again. research could provide near-term benefit to Care Facilities” program. Let’s take them in the We also have to add, in all honestly, that this patients. order you presented them. provides a high value way for Donaghue to fund New England and New York. Careful readers research, and that is still an important issue for of our annual reports and of this newsletter Using secondary data sources. Donaghue has us. The cost of data collection can take up to know that Donaghue has funded research certainly funded quite a bit of research that uses 50% or more of the project’s budget, so we’re outside Connecticut. Though in the past it was existing data sources, but this is the first time able to support more studies this way. a rare occurrence, we find it increasingly makes we’re limiting all applications in a grant program Improving care in nursing homes. It’s difficult sense to open our grant programs to a broader to that approach. We’re doing this because we to have a high quality peer review for a grant geographic region. Because “Another Look,” know that there are many sources available to program that has a wide array of topics, because is focusing on one topic, we felt that requiring answer important research questions, so this is we would need to have at least two experts in applicants to be from Connecticut institutions quite feasible. But we’re also persuaded by the each of the topics that applicants proposed. might prevent us from getting an ample number reality that a tremendous amount of research By limiting the field of research, we can recruit of letters of intent. For this program, we will be that has been funded by public or charitable a group of experts who are an excellent match soliciting applications from all six New England dollars have gone to collect data that is used for the number of applications that will need to states and New York.

Women’s Health Research at Yale Celebrates 15 Years

This year, Women’s Health Research at Yale is “The center is the national leader celebrating its 15th anniversary as a research center focused on women’s health and gender in jumpstarting innovative studies differences in health and disease. It was started on crucial areas of women’s health, with an initial investment from Donaghue of a five-year, $6.5 million grant, Donaghue’s largest integrating the study of gender to date. differences into the nation’s bio- Today, Women’s Health Research at Yale, self- medical research agenda, training supported through private funds, is a model for interdisciplinary women’s health research. The the next generation of women’s center is the national leader in jumpstarting health researchers, connecting with innovative studies on crucial areas of women’s the community through educational health, integrating the study of gender differences into the nation’s biomedical research agenda, outreach, and, above all, translating training the next generation of women’s health discoveries into real-world improve- researchers, connecting with the community needed to obtain larger, external funding to ments in health and healthcare.” through educational outreach, and, above all, further their research in their laboratories and translating discoveries into real-world improve- clinical settings, and this continues today. The ments in health and healthcare. Women’s Health quality of the research is ensured through a strin- women; ovarian cancer, the most lethal gyneco- Research at Yale’s Advisory Council is composed gent review of the annual grant applications by logical cancer; depression, twice as common in of community leaders with a shared commitment a committee of experts from diverse disciplines. women as in men; osteoporosis, a greater health to advancing women’s health research; Council Selections come from an outstanding pool of risk for women compared with men, and smoking members provide advice, raise awareness about researchers at Yale, and adhere to the highest cessation, more difficult for women than men. the center, and lead efforts to ensure that Women’s standards of scientific excellence and ethics. “As we celebrate our 15th anniversary in 2013, Health Research at Yale will exist in perpetuity. High-impact health findings flowed from the we again thank the Donaghue Foundation for its A research center focused on women’s health earliest grants, and continue to be generated. generosity, forward-looking vision and true part- and gender differences existed only as a conceptual To date, the center has awarded more than $4.4 nership in ensuring that research on women’s proposal when Raymond Andrews, then the trustee million in seed grants, and the results of these health and gender differences is advanced and of the Foundation, began meeting more than 15 pilot studies enabled the funded scientists to for sharing the belief that improving women’s years ago with Carolyn M. Mazure, PhD, Professor obtain nearly $50 million in external grants to health makes a difference in everyone’s lives,” of Psychiatry at Yale School of Medicine. further their women’s health research. said Dr. Mazure, Director of Women’s Health One of the key aspects of the initial program The studies have focused on an array of crucial Research at Yale. was to provide seed grants to allow Yale areas of women’s health, including cardiovascular For more information about Women’s Health researchers to initiate a study on a key area of disease, the greatest killer of women; breast cancer, Research at Yale or to sign up for the center’s women’s health and generate feasibility data the second-leading cause of cancer deaths among newsletter, go to www.yalewhr.org.

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R3 Grant Award R3 Grant Award Nancy Berlinger, PhD Sharon K. Inouye, MD, MPH The Hastings Center Institute for Aging Research, Hebrew Senior Life Reaching Non-Self Identifiers: Marketing the HELP 2.0 — Relevant, ready and reachable Hastings Guidelines to health care professionals Steady Vision, Project Consultant outside end of life networks Based on 1998 Donaghue Investigator Award BWB Solutions, Project Consultant of $595,000 that helped to develop the HELP Dissemination Program and original website Based on 2006 Donaghue research grant (HELP, the Hospital Elder Life Program, is an Grant Awards of $180,000 for updating and expanding innovation model of care designed to reduce the “Guidelines on the Termination of Life- delirium and functional decline of older inpatients. One year ago, Donaghue announced a new Sustaining Treatment and the Care of the The project will redesign and re-launch HELP’s Rgrant program that we3 call R3 — Making Dying,” originally developed in 1989 decade old website to advance the spread of Research Relevant & Ready. This was a new Using prospective user research, the project the Hospital Elder Life Program by providing venture for us, and we’re excited to seeks to expand the use of the guidelines to enhanced functionality and more robust support announce the six award winners for this clinicians who care for patients facing decisions to current and prospective user hospitals, inter- program. about life-sustaining treatment or nearing ested seniors, family members, and caregivers. R3 was developed to help promote the end of life but do not view themselves as knowledge created from Donaghue-funded providing end of life care. The results will R3 Grant Award research so that it will improve health. In be used to develop and pilot a web-based Linda Mayes, MD and Lois Sadler, PhD Guidelines implementation toolkit tailored for Yale School of Medicine, Child Study Center “In creating this program, these audiences. Minding the Baby® Home Visitation Program: we recognize that expertise Transitioning from research to service R3 Grant Award Frameworks Institute and RPM Health, from disciplines outside those Michelle M. Cloutier, MD Project Consultants traditionally eligible for research Connecticut Children’s Medical Center funding is needed for scaling, Payer-Provider Portal to Enhance Easy Breathing Based on 2005 grant of $240,000 to conduct dissemination, and sustain- Adoption a phase II pilot study of Minding the Baby’s® Rising Tide Health, Project Consultant home visiting intervention program in improving ability of evidence-based health and life course of young first-time at-risk programs and practices.” Based on 1998 grant of $1,200,000 to test mothers, their children, and families. effectiveness of a best-practice model for This project will assist MTB developers in creating this program, we recognize that asthma diagnosis and treatment in Hartford determining the program’s readiness to transition expertise from disciplines outside those pediatric health clinics from a research program to a service program traditionally eligible for research funding The project will develop and pilot a payer- with the potential to sustain itself and grow. is needed for scaling, dissemination, and based provider portal as the vehicle to integrate sustainability of evidence-based programs a web-based Easy Breathing application with R3 Grant Award and practices. Donaghue grantees, past and multiple EHRs. Diane E. Meier, MD present, were eligible for the R3 program. Center To Advance Palliative Care With R3, it’s the Foundation’s goal to R3 Grant Award IT Enhancement/Integration for the National provide researchers with financial support Judith Fifield, PhD Palliative Care Registry™ — Data drives access to to access those experts, thus better posi- University of Connecticut Health Center quality tioning the health interventions to grow Translating Sister Talk for Dissemination in DatStat, Project Consultant and be sustained following the completion New York City of the research phase. The result? Stronger Wellspring Consulting and Burke PR, Based on 2008 grant of $210,363 to CAPC to collect research and improved health. Project Consultants and analyze data associated with successful Each grantee will receive $55,000 to hospital palliative care in order to develop the conduct their project over an 18 month Based on 2002 grant of $900,000 to test National Palliative Care Registry™ a repository period. R3 funds will enable the grantees to effectiveness of a faith-based healthy lifestyle- for benchmarking and comparing hospital-based access experts in areas relevant to scaling, weight loss program, developed and tested palliative care programs spread, and implementation. The winners, collaboratively by researchers, hospital leaders This project will provide resources to undertake their consulting partners, and their projects and the leadership and volunteers of 12 African- fundamental technical improvements to CAPC’s are highlighted here. We hope the R3 American churches National Palliative Care Registry™, so it can produce grant program will help researchers make The project will adapt and rebrand SisterTalk reliable, web-based, scalable systems and progress in preparing their health interven- in a collaboration with Emblem Health, one of immediate real-time results reporting for hundreds tions for adoption and use; we know it will New York’s largest health plans, to meet the of users simultaneously to serve a growing and help Donaghue be smarter in our future expectations, motivations and needs of Emblem diverse set of users in multiple clinical and research grant programs. Look for more and its members in target neighborhoods in community palliative care settings. information about the R3 grantees and Manhattan. their projects on the Donaghue website soon. In the meantime, please contact The Foundation convened an R3 advisory group to provide it with guidance and review the letters the Donaghue office if you wish to learn of intent and applications to the program. See the next page for brief bios of the advisory group more. members.

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Donaghue Foundation: R3 Advisory Group Blinded Reviews?

Thank you to our R3 Advisers who have assisted minorities in two large communities. She is project Letters of intent for Donaghue’s “Another us with this program. director and editor-in-chief for the AHRQ Health Look: Better Health for Elders in Care Facili- Care Innovations Exchange. She served on the ties” grant program will be reviewed for Konstantine Drakonakis Donaghue Foundation’s New Venture Advisory the research idea only. Applicants’ names Director, LaunchCapital, LLC Group (2010-2011) that provided guidance to the and their institutions will not be seen by the Konstantine Drakonakis is an experienced early Foundation on avenues for addressing gaps Donaghue staff and science review com- stage investor focused on proprietary technologies between health research and its use, and she was mittee members who are participating in in New York, New Jersey and Connecticut. He a panelist for Donaghue’s 2008 BeyondEureka! this phase of the review process. When the is a board certified Professional Engineer and conference. Nieva holds a PhD in Organizational full applications are reviewed, however, all is a member of the National Civil Engineering Psychology from the University of Michigan. information contained in the application Honors Society, and as an “entrepreneurial including applicants’ bios and their institu- engineer,” Drakonakis gravitates to technology Laurel Pickering tions will be a part of the review process. companies within the software, med-tech President & CEO, Northeast Business Group on Why is Donaghue doing this? We’re and green-tech markets. Since joining the Health always looking for ways to test innovative LaunchCapital team, he has developed invest- Laurel Pickering is President and CEO of the ideas toward the goal of improving our ment partnerships with leading universities Northeast Business Group on Health, a 190 grants and grantmaking. A recent article such as Yale University, University of Connecticut, member business coalition representing over in Science (May 25, 2012, Volume 336) that Columbia University, the University of 1 million covered lives, committed to market- reported on a National Science Foundation Pennsylvania, and the University of Virginia. based health care reform, quality improvement pilot program called “the Big Pitch” caught Drakonakis holds a Masters in Environmental and value-based purchasing. At NEBGH, our eye. NSF asked two different review Management from Yale University and a Civil Pickering focuses on mobilizing the business groups to rate the same proposals, only and Environmental Engineering degree from the community to drive improvement in healthcare, one review group did not have applicants’ University of Vermont. providing access to health insurance for small names or institutions. The two review businesses by creating a health insurance groups came up with different recommen- Marie Massaro exchange, and organizing health plans to work dations as to which proposals should be Massaro Consulting and member of Donaghue’s together to improve quality. She currently funded. This doesn’t answer the question of Policy Advisory Committee serves on NCQA’s Standards Committee, the which review group produced the “better” Marie Massaro is founder and principal of Boards of Directors for The Leapfrog Group and or “more accurate” rating, but it does point Massaro Consulting, which assists grant makers National Business Coalition on Health, CDC’s to the notion — as others have, too — that and community organizations by conducting Business and Labor Responds to AIDS Board of network or reputation bias can play a large philanthropic research, developing grantmaking Business and Labor Partners, the Commissioner part in the evaluation of research proposals. parameters including RFPs, conducting program of NYC Department of Health and Mental Because this is only the second time that evaluations, and fostering productive community Hygiene’s Advisory Council, and the Community Donaghue has had a multi-state competi- partnerships. Since February 2011, she has Advisory Committee of the New York State tive grant program, we thought it would be served as coordinator for the Wethersfield Early Health Foundation. Pickering received her BA a good idea to focus on the core research Readiness Council, a community collaborative in Anthropology from SUNY Albany and MPH idea at the letter of intent phase. working to improve the health and education from Emory University. outcomes of children ages birth to eight. Before — continued on page 7 starting her own firm, Massaro was a program officer at The Aetna Foundation for nine years. She received her Bachelor’s degree in Economics from the University of Connecticut. She serves on the University of Connecticut School of Dental Medicine Advisory Committee and was on the Wethersfield Board of Education from 2007 to 2009. Massaro joined the Donaghue Foundation Policy Advisory Committee in 2010.

Veronica Nieva Vice President, Westat Ronie Nieva oversees a portfolio of research and dissemination projects at Westat on the improvement of health care safety and quality and has recently launched a new program focusing on the use of health information tech- nology for health improvement. Her research on safety culture has resulted in AHRQ’s public use suite of Patient Safety Culture Measures that is used by over 500 hospitals in the U.S. and in more than 30 countries. Nieva is chair of the expert panel on a NIH-sponsored grant to develop performance measures of community care coordination and is senior adviser for a project to implement comparative effectiveness The Donaghue Foundation R3 Advisory Group (L to R) Marie Massaro, Julio Urbina, C. Todd Staub, research findings to improve health care for Konstantine Drakonakis, Laurel Pickering, and Eleanor L. Tandler. Missing from photo: Veronica Nieva

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The Robert Wood Johnson Foundation and Donaghue Offer Second Round of Grants for Behavioral Economics Research

Progress toward solving tough health and health care problems often has been too slow or limited in scope. However, one area of promise is the application of the theory behind behavioral economics to health and health care. By recognizing that individual decision-making systematically deviates from traditional economic models that typically presume people behave rationally, behavioral economics offers insights that conventional economics models might miss. Donaghue has been working with the Pioneer Ann Bonham, AAMC Chief Scientific Officer portfolio of The Robert Wood Johnson be used to test promising behavioral economic Advancing Effectiveness Research and Foundation and together we are soliciting a approaches. This funding is intended to support Implementation Science in our Own second round of proposals to encourage creative initiatives that have real potential of being used Backyards: A Donaghue-AAMC Grant and rigorous tests of ways to apply behavioral by these organizations after the research phase Opportunity for Academic Medical economics principles to persistent and should these initiatives prove effective. While Centers perplexing health and health care problems. We we are particularly interested in supporting the hope to discover new interventions and insights testing of ideas to reduce utilization of low-value Donaghue is working with the Association that have potential to dramatically improve care, we will also accept any investigator-initiated of American Medical Colleges to study a the way health care is delivered and health is ideas that are consistent with the broader set of new approach to stimulate and enhance the promoted and preserved. We are particularly program goals and have the potential to offer creation of learning health systems within interested in supporting experiments that test breakthrough solutions to persistent and medical schools and teaching hospitals. The innovative solutions to the challenge of reducing perplexing health and health care problems. goal is to facilitate sustainable partnerships the use of low-value services in health care. This Although we expect that many of the most to use evidence from research to improve topic is particularly important given the rising promising proposals will come in the form of quality, safety, equity, and system effective- costs and unaffordability of health care in the prospective experiments that point more clearly ness. Donaghue will provide a four-year, United States, but has been difficult to change to policy solutions, we also recognize that $600,000 grant to AAMC to establish two in part due to perverse incentives in a fee-for- important work can be achieved through careful competitively selected pilot projects that service environment. analyses of existing observational data. will seek new ways to incorporate research findings into clinical care and then conduct “Through this funding opportunity, The Robert Wood Johnson an evaluation of the impact of these two projects. Foundation and Donaghue are particularly interested in funding Donaghue will work with AAMC to proposals in which academic teams collaborate with an outside develop the RFP, review the applications organization, corporation, or partner that has a population and/or and evaluation strategy, and participate in consultations to awardees. AAMC will be an infrastructure that can be used to test promising behavioral working with two of its communities — the economic approaches.” Research on Care Community, representing the health research component health We expect that the projects funded under systems and the Chief Medical Officers Group, this initiative will complement the work of the representing the clinical implementation RWJF-supported Choosing Wisely® initiative and management component — to conduct (www.choosingwisely.org), launched by the We expect to make approximately five awards of the grant program for the two pilot projects, ABIM Foundation and many of the nation’s leading up to $200,000 each under this call for propos- monitor progress, evaluate the changes they medical specialty societies. In partnership with als. Projects will last for up to two years each. have made, and disseminate findings among Consumer Reports, Choosing Wisely aims to help The Robert Wood Johnson Foundation and the AAMC ROCC members (information about physicians and patients engage in conversations Donaghue, in collaboration with the LDI Center the ROCC can be found at www.aamc.org/ about the overuse of tests and procedures; it for Health Incentives and Behavioral Economics initiatives/rocc). also supports physician efforts to help patients at the University of Pennsylvania, began soliciting AAMC Chief Scientific Officer, Ann Bonham, make smart and effective care choices. Applying proposals for this work on March 1, 2013; the noted that “the AAMC is proud to partner behavioral economics to this challenge has the call for proposals will close April 17, 2013. If you with the Donaghue Foundation in this potential to support and extend this work by are interested in learning more, please contact innovative initiative that will enhance the suggesting and testing approaches that encourage [email protected] or call the Donaghue use of science in the process of implementation patients and physicians to choose wisely about office. and generate new knowledge to improve which services to use. healthcare.” Through this funding opportunity, The Robert The call for proposals will be available Wood Johnson Foundation and Donaghue are in May. For more information about this particularly interested in funding proposals in opportunity or AAMC’s Research on Care which academic teams collaborate with an outside Communities, please contact Alex Ommaya organization, corporation, or partner that has at [email protected] a population and/or an infrastructure that can

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Join us for the Foundation’s 2013 Beyond Eureka! Conference on May 3 How is Science Serving Us? Why this question matters and how you can shape the answer

Science can hold the key to resolving many of literacy. Ms. Cavalier will also discuss her work the world’s largest problems — for example, in developing a structure to provide objective how we can provide food to a growing planet, and authoritative analyses of complex scientific treat a pandemic, or understand the roots of and technical issues to the public and elected genocide so we can prevent the next one. But officials. In addition to SciStarter.com, Ms. Cavalier before science can save us, does science need is the creator of “Science Cheerleaders,” to be saved from conditions that threaten comprised of more than 200 NFL and NBA its vibrancy? This issue will be discussed at cheerleaders who are also scientists and engineers. Donaghue’s Beyond Eureka! conference on May Science Cheerleaders playfully challenge stereo- 3 at the Hartford Marriott Farmington between types, inspire young women to consider science 7:30 AM and 12:30 PM. careers, and involve people from all walks of Arturo Casadevall, MD, PhD Our first speaker, Arturo Casadevall, MD, PhD, life in science projects. Cavalier is a senior adviser is the Leo and Julia Forchheimer Professor of at Discover Magazine, and she holds a Masters Microbiology & Immunology at the Albert Einstein Degree in Biology from the University of College of Medicine of Yeshiva University in Pennsylvania. the Bronx, New York. He is Chairman of the After these two presentations, Guy Fish, MD, Department of Microbiology and Immunology MBA, Vice President of Fletcher Spaght, will and served as Director of the Division of moderate a discussion between the two speakers Infectious Diseases at the Montefiore Medical using questions from the audience and his more Center at the Albert Einstein College of Medicine than 25 years of experience in healthcare, life from 2000-2006. Dr. Casadevall will provide a sciences, and biotechnology. historical perspective on modern science and its Concurrent with the conference, Donaghue is Darlene Cavalier, MS contribution to health and prosperity, including organizing a “Science Opportunities Fair” with how the public’s view of science and scientists local science organizations to highlight their has evolved. He will discuss the current external programs that involve children in science. threats to science, such as the lack of science Although registration for the conference is literacy in society, as well as internal threats to required, the conference is free and anyone science related to how research is funded, interested in learning about important trends conducted, and rewarded. in science today are welcome to attend. CME Picking up on Dr. Casadevall’s themes of credits will be available for some disciplines. science and society, Darlene Cavalier, founder of More information, including more extensive SciStarter.com, a popular online citizen science speaker bios and a link to the registration page, community, will focus on citizen involvement in are available on the Foundation’s website the conduct of science and promoting science www.donaghue.org. Guy Fish, MD, MBA

R3 Advisory Group — continued from page 5

C. Todd Staub served as a panel moderator for the Donaghue MBA from New York University’s Stern School Board Chairman, ProHealth Physicians Foundation’s 2011 BeyondEureka! conference. of Business and earned a bachelor’s degree in Todd Staub is the Chairman of the Board and Economics from the University of Massachusetts. a founding member of ProHealth Physicians, Eleanor L. Tandler an integrated primary care group practice in Founder & CEO, NovaTract Surgical Julio Urbina Connecticut established in 1997, and is also a Ellie Tandler is founder and CEO of NovaTract Director, Health Aging Program, practicing internist. ProHealth, which serves Surgical, Inc., a venture-backed start-up company Samuels Foundation 350,000 patients in more than 70 locations focused on innovative devices for minimally inva- Julio Urbina is the Vice President at the Fan Fox throughout the state, was recently selected by sive surgeries. Based on technology developed and Leslie R. Samuels Foundation and is also the Centers for Medicare and Medicaid as one of at Yale University, the company’s first product the Director of its Healthy Aging Program. He is 106 new Accountable Care Organizations. Staub addresses the need for better visualization and responsible for helping the Foundation identify was instrumental in ProHealth’s implementing manipulation of organs during surgery while programs and projects that meet its goals. Prior an integrated EHR/practice management system reducing the number of incisions. Prior to to joining the Samuels Foundation, Urbina held and in achieving NCQA Level 3 Patient-Centered NovaTract, Tandler was the Director of Venture management positions at healthcare agencies Medical Home recognition in all practice sites. Development at UConn R & D Corporation where and hospitals in New York City and Connecticut. He helped establish the Connecticut Center she worked to create new business start-ups In addition, he spent twenty years as a paramedic. for Primary Care, a non-profit organization based on innovative technologies developed by He earned a Bachelor‘s degree in Public Admini- devoted to research and education on primary the faculty and staff at the University. Prior to stration from the City University of New York, an care issues and the Primary Care Coalition that, she spent five years as a venture capital MPH from the Yale University School of Public of Connecticut, which brings together front- investor with Radius Ventures, LLC, a health and Health, and a PhD in Social Policy from the Heller line providers from diverse practice settings life sciences focused, early-stage venture capital School for Social Policy and Management at Brandeis across the state, including physicians, nurse firm based in New York City with approximately University. Urbina was the moderator for practitioners, and physician assistants. He also $230 million under management. She received a Donaghue’s Beyond Eureka! conference in 2010.

7 The Patrick and Catherine Weldon NON-PROFIT ORG Donaghue Medical Research Foundation U.S. POSTAGE 18 North Main Street PAID West Hartford, CT 06107-1919 hartford, CT 860.521.9011 Permit No. 2648 www.donaghue.org

The Patrick and Catherine Weldon Donaghue Medical Research Foundation is a charitable trust created pursuant to the will of Ethel F. Donaghue, late of West Hartford, Connecticut. The Foundation, which began operations in 1991, is governed by Bank of America and Lynne Garner, Trustees. The Foundation is exempt from federal income tax under Section 501(c)(3) of the Internal Revenue Code of 1986, is a private foundation within the meaning of Code Section 509(a), and is subject to the jurisdiction of the Probate Court for the District of West Hartford.

Spring 2013 Practically Speaking The Patrick and Catherine Weldon Donaghue Medical Research Foundation

Join Us on May 3, 2013 Arturo Casadevall, Md, Phd darlene Cavalier, MS Guy Fish, Md

BeyondEurEka! 2013 How is The Trustees of the Patrick and Catherine Weldon Donaghue Medical Research Foundation invite you to our 2013 Conference.

Beyond Eureka! 2013 conference will explore the role of science in our society today by highlighting some of the key issues and trends shaping the way that science is carried out and what this Science means for the future. Serving Us? Friday, May 3, 2013 7:30am – 12:30pm Why this question matters and Hartford Marriott Farmington how you can shape the answer Farmington, Connecticut

Although registration for the conference is required, the conference is free and anyone interested in learning about important trends in science today are welcome to attend. CME credits will be available for some disciplines. More information, including more extensive speaker bios and a link to the registration page, are available on the Foundation’s website www.donaghue.org. See the article on the conference on page 7 of this newsletter.