bioRxiv preprint doi: https://doi.org/10.1101/2020.12.09.417519; this version posted December 9, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. Intra-host variability in global SARS-CoV-2 genomes as signatures of RNA editing: implications in viral and host response outcomes Running title RNA editing induced diversity in SARS-CoV-2 genomes 1 1 1,2 1 3 3 Ankit K. Pathak , Saman Fatihi , Tahseen Abbas , Bharathram Uppili , Gyan Prakash Mishra , Arup Ghosh , 4 1 1,2 1,2 1,2 Sofia Banu , Rahul C. Bhoyar , Abhinav Jain , Mohit Kumar Divakar , Mohamed Imran , Mohammed 1 4 3 1 1 Faruq , Divya Tej Sowpati , Sunil K. Raghav , Lipi Thukral , Mitali Mukerji * 1 CSIR - Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi, India 2 Academy for Scientific and Innovative Research, Human Resource Development Centre Campus, Ghaziabad, Uttar Pradesh, India 3 Institute of Life Sciences, Bhubaneswar, Odisha, India 4 CSIR - Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, Telangana, India *Correspondence:
[email protected] bioRxiv preprint doi: https://doi.org/10.1101/2020.12.09.417519; this version posted December 9, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license.